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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:RCCD1-BLM

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: RCCD1-BLM
FusionPDB ID: 73298
FusionGDB2.0 ID: 73298
HgeneTgene
Gene symbol

RCCD1

BLM

Gene ID

91433

641

Gene nameRCC1 domain containing 1BLM RecQ like helicase
Synonyms-BS|MGRISCE1|RECQ2|RECQL2|RECQL3
Cytomap

15q26.1

15q26.1

Type of geneprotein-codingprotein-coding
DescriptionRCC1 domain-containing protein 1Bloom syndrome proteinBloom syndrome RecQ like helicaseBloom syndrome, RecQ helicase-likeDNA helicase, RecQ-like type 2recQ protein-like 3
Modification date2020031320200313
UniProtAcc.

Q13867

Ensembl transtripts involved in fusion geneENST idsENST00000556774, ENST00000394258, 
ENST00000555155, ENST00000556618, 
ENST00000355112, ENST00000560509, 
ENST00000560136, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score2 X 8 X 2=327 X 13 X 3=273
# samples 38
** MAII scorelog2(3/32*10)=-0.0931094043914815
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/273*10)=-1.77082904603249
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: RCCD1 [Title/Abstract] AND BLM [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)RCCD1(91498178)-BLM(91326052), # samples:2
Anticipated loss of major functional domain due to fusion event.RCCD1-BLM seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
RCCD1-BLM seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
RCCD1-BLM seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
RCCD1-BLM seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
RCCD1-BLM seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
RCCD1-BLM seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
RCCD1-BLM seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneBLM

GO:0000729

DNA double-strand break processing

21325134

TgeneBLM

GO:0006974

cellular response to DNA damage stimulus

23509288

TgeneBLM

GO:0007095

mitotic G2 DNA damage checkpoint

11309417

TgeneBLM

GO:0010165

response to X-ray

11309417

TgeneBLM

GO:0031297

replication fork processing

17115688

TgeneBLM

GO:0032508

DNA duplex unwinding

11735402|24816114|25901030

TgeneBLM

GO:0044806

G-quadruplex DNA unwinding

11735402

TgeneBLM

GO:0045893

positive regulation of transcription, DNA-templated

11781842

TgeneBLM

GO:0051259

protein complex oligomerization

28228481

TgeneBLM

GO:0051260

protein homooligomerization

28228481

TgeneBLM

GO:0061820

telomeric D-loop disassembly

19734539

TgeneBLM

GO:0071479

cellular response to ionizing radiation

23509288

TgeneBLM

GO:0072711

cellular response to hydroxyurea

23509288

TgeneBLM

GO:0072757

cellular response to camptothecin

23509288


check buttonFusion gene breakpoints across RCCD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BLM (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91498177

+BLMchr15

91326051

+
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91498177

+BLMchr15

91328150

+
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91498178

-BLMchr15

91326052

+
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91498178

+BLMchr15

91326052

+
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91498178

+BLMchr15

91328151

+
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91499113

+BLMchr15

91326052

+
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91500733

+BLMchr15

91326052

+
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91500954

+BLMchr15

91326051

+
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91500954

+BLMchr15

91328150

+
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91500955

+BLMchr15

91326052

+
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91500955

+BLMchr15

91328151

+
ChimerDB4LUADTCGA-38-4630-01ARCCD1chr15

91505004

+BLMchr15

91290619

+
ChimerDB4LUADTCGA-38-4630RCCD1chr15

91498178

+BLMchr15

91326051

+
ChimerDB4LUADTCGA-38-4630RCCD1chr15

91498178

+BLMchr15

91328150

+
ChimerDB4LUADTCGA-38-4630RCCD1chr15

91500955

+BLMchr15

91328150

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394258RCCD1chr1591500955+ENST00000355112BLMchr1591328150+2656881192472817
ENST00000394258RCCD1chr1591500955+ENST00000560509BLMchr1591328150+2134881192079686
ENST00000555155RCCD1chr1591500955+ENST00000355112BLMchr1591328150+264587082461817
ENST00000555155RCCD1chr1591500955+ENST00000560509BLMchr1591328150+212387082068686
ENST00000556618RCCD1chr1591500955+ENST00000355112BLMchr1591328150+25768011222392756
ENST00000556618RCCD1chr1591500955+ENST00000560509BLMchr1591328150+20548011221999625
ENST00000394258RCCD1chr1591500955+ENST00000355112BLMchr1591328151+2656881192472817
ENST00000394258RCCD1chr1591500955+ENST00000560509BLMchr1591328151+2134881192079686
ENST00000555155RCCD1chr1591500955+ENST00000355112BLMchr1591328151+264587082461817
ENST00000555155RCCD1chr1591500955+ENST00000560509BLMchr1591328151+212387082068686
ENST00000556618RCCD1chr1591500955+ENST00000355112BLMchr1591328151+25768011222392756
ENST00000556618RCCD1chr1591500955+ENST00000560509BLMchr1591328151+20548011221999625
ENST00000394258RCCD1chr1591500733+ENST00000355112BLMchr1591326052+2641759192457812
ENST00000394258RCCD1chr1591500733+ENST00000560509BLMchr1591326052+2119759192064681
ENST00000555155RCCD1chr1591500733+ENST00000355112BLMchr1591326052+263074882446812
ENST00000555155RCCD1chr1591500733+ENST00000560509BLMchr1591326052+210874882053681
ENST00000556618RCCD1chr1591500733+ENST00000355112BLMchr1591326052+25616791222377751
ENST00000556618RCCD1chr1591500733+ENST00000560509BLMchr1591326052+20396791221984620
ENST00000394258RCCD1chr1591500954+ENST00000355112BLMchr1591328150+2656881192472817
ENST00000394258RCCD1chr1591500954+ENST00000560509BLMchr1591328150+2134881192079686
ENST00000555155RCCD1chr1591500954+ENST00000355112BLMchr1591328150+264587082461817
ENST00000555155RCCD1chr1591500954+ENST00000560509BLMchr1591328150+212387082068686
ENST00000556618RCCD1chr1591500954+ENST00000355112BLMchr1591328150+25768011222392756
ENST00000556618RCCD1chr1591500954+ENST00000560509BLMchr1591328150+20548011221999625

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394258ENST00000355112RCCD1chr1591500955+BLMchr1591328150+0.0019756060.99802446
ENST00000394258ENST00000560509RCCD1chr1591500955+BLMchr1591328150+0.0100234320.9899766
ENST00000555155ENST00000355112RCCD1chr1591500955+BLMchr1591328150+0.0020194620.99798054
ENST00000555155ENST00000560509RCCD1chr1591500955+BLMchr1591328150+0.0103169140.98968303
ENST00000556618ENST00000355112RCCD1chr1591500955+BLMchr1591328150+0.0021976110.99780244
ENST00000556618ENST00000560509RCCD1chr1591500955+BLMchr1591328150+0.0113788190.9886212
ENST00000394258ENST00000355112RCCD1chr1591500955+BLMchr1591328151+0.0019756060.99802446
ENST00000394258ENST00000560509RCCD1chr1591500955+BLMchr1591328151+0.0100234320.9899766
ENST00000555155ENST00000355112RCCD1chr1591500955+BLMchr1591328151+0.0020194620.99798054
ENST00000555155ENST00000560509RCCD1chr1591500955+BLMchr1591328151+0.0103169140.98968303
ENST00000556618ENST00000355112RCCD1chr1591500955+BLMchr1591328151+0.0021976110.99780244
ENST00000556618ENST00000560509RCCD1chr1591500955+BLMchr1591328151+0.0113788190.9886212
ENST00000394258ENST00000355112RCCD1chr1591500733+BLMchr1591326052+0.0016132630.99838674
ENST00000394258ENST00000560509RCCD1chr1591500733+BLMchr1591326052+0.0065977430.9934023
ENST00000555155ENST00000355112RCCD1chr1591500733+BLMchr1591326052+0.0016416980.9983583
ENST00000555155ENST00000560509RCCD1chr1591500733+BLMchr1591326052+0.0067661580.99323386
ENST00000556618ENST00000355112RCCD1chr1591500733+BLMchr1591326052+0.0017634730.99823654
ENST00000556618ENST00000560509RCCD1chr1591500733+BLMchr1591326052+0.0076647550.99233526
ENST00000394258ENST00000355112RCCD1chr1591500954+BLMchr1591328150+0.0019756060.99802446
ENST00000394258ENST00000560509RCCD1chr1591500954+BLMchr1591328150+0.0100234320.9899766
ENST00000555155ENST00000355112RCCD1chr1591500954+BLMchr1591328150+0.0020194620.99798054
ENST00000555155ENST00000560509RCCD1chr1591500954+BLMchr1591328150+0.0103169140.98968303
ENST00000556618ENST00000355112RCCD1chr1591500954+BLMchr1591328150+0.0021976110.99780244
ENST00000556618ENST00000560509RCCD1chr1591500954+BLMchr1591328150+0.0113788190.9886212

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>73298_73298_1_RCCD1-BLM_RCCD1_chr15_91500733_ENST00000394258_BLM_chr15_91326052_ENST00000355112_length(amino acids)=812AA_BP=241
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRFSMSFNRHNLKYYVLPKKPKKVA
FDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHAS
LPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFC
KKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRHNAERL
FKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGV
HYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHY
FASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFLKPSYA

--------------------------------------------------------------

>73298_73298_2_RCCD1-BLM_RCCD1_chr15_91500733_ENST00000394258_BLM_chr15_91326052_ENST00000560509_length(amino acids)=681AA_BP=241
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRFSMSFNRHNLKYYVLPKKPKKVA
FDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHAS
LPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFC
KKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLESLSSDPEVLLQIDGVTEDKLEKYGA
EVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRK

--------------------------------------------------------------

>73298_73298_3_RCCD1-BLM_RCCD1_chr15_91500733_ENST00000555155_BLM_chr15_91326052_ENST00000355112_length(amino acids)=812AA_BP=241
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRFSMSFNRHNLKYYVLPKKPKKVA
FDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHAS
LPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFC
KKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRHNAERL
FKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGV
HYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHY
FASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFLKPSYA

--------------------------------------------------------------

>73298_73298_4_RCCD1-BLM_RCCD1_chr15_91500733_ENST00000555155_BLM_chr15_91326052_ENST00000560509_length(amino acids)=681AA_BP=241
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRFSMSFNRHNLKYYVLPKKPKKVA
FDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHAS
LPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFC
KKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLESLSSDPEVLLQIDGVTEDKLEKYGA
EVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRK

--------------------------------------------------------------

>73298_73298_5_RCCD1-BLM_RCCD1_chr15_91500733_ENST00000556618_BLM_chr15_91326052_ENST00000355112_length(amino acids)=751AA_BP=180
MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGP
GPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVF
SWGGGRFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWIN
QDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSM
VHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVD
IFLGSKSAKIQSGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVA
KVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSS
PGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTS

--------------------------------------------------------------

>73298_73298_6_RCCD1-BLM_RCCD1_chr15_91500733_ENST00000556618_BLM_chr15_91326052_ENST00000560509_length(amino acids)=620AA_BP=180
MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGP
GPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVF
SWGGGRFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWIN
QDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSM
VHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVD
IFLESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRK

--------------------------------------------------------------

>73298_73298_7_RCCD1-BLM_RCCD1_chr15_91500954_ENST00000394258_BLM_chr15_91328150_ENST00000355112_length(amino acids)=817AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLG
KVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFL

--------------------------------------------------------------

>73298_73298_8_RCCD1-BLM_RCCD1_chr15_91500954_ENST00000394258_BLM_chr15_91328150_ENST00000560509_length(amino acids)=686AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLESLSSDPEVLLQIDGVTEDKL
EKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGS

--------------------------------------------------------------

>73298_73298_9_RCCD1-BLM_RCCD1_chr15_91500954_ENST00000555155_BLM_chr15_91328150_ENST00000355112_length(amino acids)=817AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLG
KVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFL

--------------------------------------------------------------

>73298_73298_10_RCCD1-BLM_RCCD1_chr15_91500954_ENST00000555155_BLM_chr15_91328150_ENST00000560509_length(amino acids)=686AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLESLSSDPEVLLQIDGVTEDKL
EKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGS

--------------------------------------------------------------

>73298_73298_11_RCCD1-BLM_RCCD1_chr15_91500954_ENST00000556618_BLM_chr15_91328150_ENST00000355112_length(amino acids)=756AA_BP=226
MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGP
GPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVF
SWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQ
QKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFN
NLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTM
NMLVDIFLGSKSAKIQSGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQ
KALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSP
AEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSS

--------------------------------------------------------------

>73298_73298_12_RCCD1-BLM_RCCD1_chr15_91500954_ENST00000556618_BLM_chr15_91328150_ENST00000560509_length(amino acids)=625AA_BP=226
MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGP
GPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVF
SWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQ
QKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFN
NLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTM
NMLVDIFLESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRN

--------------------------------------------------------------

>73298_73298_13_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000394258_BLM_chr15_91328150_ENST00000355112_length(amino acids)=817AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLG
KVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFL

--------------------------------------------------------------

>73298_73298_14_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000394258_BLM_chr15_91328150_ENST00000560509_length(amino acids)=686AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLESLSSDPEVLLQIDGVTEDKL
EKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGS

--------------------------------------------------------------

>73298_73298_15_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000394258_BLM_chr15_91328151_ENST00000355112_length(amino acids)=817AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLG
KVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFL

--------------------------------------------------------------

>73298_73298_16_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000394258_BLM_chr15_91328151_ENST00000560509_length(amino acids)=686AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLESLSSDPEVLLQIDGVTEDKL
EKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGS

--------------------------------------------------------------

>73298_73298_17_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000555155_BLM_chr15_91328150_ENST00000355112_length(amino acids)=817AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLG
KVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFL

--------------------------------------------------------------

>73298_73298_18_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000555155_BLM_chr15_91328150_ENST00000560509_length(amino acids)=686AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLESLSSDPEVLLQIDGVTEDKL
EKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGS

--------------------------------------------------------------

>73298_73298_19_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000555155_BLM_chr15_91328151_ENST00000355112_length(amino acids)=817AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLG
KVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFL

--------------------------------------------------------------

>73298_73298_20_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000555155_BLM_chr15_91328151_ENST00000560509_length(amino acids)=686AA_BP=287
MLGHESGACRVLSCRGPGTEIRQLQPLEGQRLASVPLAGSSQESPRARRSQAAAGRGRCSGMAEERPGAWFGFGFCGFGQELGSGRGRQV
HSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEA
EGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQG
LVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGF
NPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLESLSSDPEVLLQIDGVTEDKL
EKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGS

--------------------------------------------------------------

>73298_73298_21_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000556618_BLM_chr15_91328150_ENST00000355112_length(amino acids)=756AA_BP=226
MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGP
GPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVF
SWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQ
QKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFN
NLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTM
NMLVDIFLGSKSAKIQSGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQ
KALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSP
AEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSS

--------------------------------------------------------------

>73298_73298_22_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000556618_BLM_chr15_91328150_ENST00000560509_length(amino acids)=625AA_BP=226
MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGP
GPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVF
SWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQ
QKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFN
NLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTM
NMLVDIFLESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRN

--------------------------------------------------------------

>73298_73298_23_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000556618_BLM_chr15_91328151_ENST00000355112_length(amino acids)=756AA_BP=226
MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGP
GPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVF
SWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQ
QKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFN
NLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTM
NMLVDIFLGSKSAKIQSGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQ
KALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSP
AEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSS

--------------------------------------------------------------

>73298_73298_24_RCCD1-BLM_RCCD1_chr15_91500955_ENST00000556618_BLM_chr15_91328151_ENST00000560509_length(amino acids)=625AA_BP=226
MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGP
GPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVF
SWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSDDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQ
QKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFN
NLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTM
NMLVDIFLESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRN

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:91498178/chr15:91326052)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.BLM

Q13867

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRCCD1chr15:91500733chr15:91326052ENST00000394258+386_56185.66666666666666377.0RepeatNote=RCC1 1
HgeneRCCD1chr15:91500733chr15:91326052ENST00000556618+396_56185.66666666666666447.0RepeatNote=RCC1 1
HgeneRCCD1chr15:91500954chr15:91328150ENST00000394258+48176_227226.33333333333334377.0RepeatNote=RCC1 2
HgeneRCCD1chr15:91500954chr15:91328150ENST00000394258+486_56226.33333333333334377.0RepeatNote=RCC1 1
HgeneRCCD1chr15:91500954chr15:91328150ENST00000556618+49176_227226.33333333333334447.0RepeatNote=RCC1 2
HgeneRCCD1chr15:91500954chr15:91328150ENST00000556618+496_56226.33333333333334447.0RepeatNote=RCC1 1
HgeneRCCD1chr15:91500955chr15:91328150ENST00000394258+48176_227226.33333333333334377.0RepeatNote=RCC1 2
HgeneRCCD1chr15:91500955chr15:91328150ENST00000394258+486_56226.33333333333334377.0RepeatNote=RCC1 1
HgeneRCCD1chr15:91500955chr15:91328150ENST00000556618+49176_227226.33333333333334447.0RepeatNote=RCC1 2
HgeneRCCD1chr15:91500955chr15:91328150ENST00000556618+496_56226.33333333333334447.0RepeatNote=RCC1 1
HgeneRCCD1chr15:91500955chr15:91328151ENST00000394258+48176_227226.33333333333334377.0RepeatNote=RCC1 2
HgeneRCCD1chr15:91500955chr15:91328151ENST00000394258+486_56226.33333333333334377.0RepeatNote=RCC1 1
HgeneRCCD1chr15:91500955chr15:91328151ENST00000556618+49176_227226.33333333333334447.0RepeatNote=RCC1 2
HgeneRCCD1chr15:91500955chr15:91328151ENST00000556618+496_56226.33333333333334447.0RepeatNote=RCC1 1
TgeneBLMchr15:91500733chr15:91326052ENST0000035511211221212_1292851.66666666666661418.0DomainHRDC
TgeneBLMchr15:91500733chr15:91326052ENST000003551121122877_1024851.66666666666661418.0DomainHelicase C-terminal
TgeneBLMchr15:91500954chr15:91328150ENST0000035511212221212_1292887.33333333333341418.0DomainHRDC
TgeneBLMchr15:91500955chr15:91328150ENST0000035511212221212_1292887.33333333333341418.0DomainHRDC
TgeneBLMchr15:91500955chr15:91328151ENST0000035511212221212_1292887.33333333333341418.0DomainHRDC
TgeneBLMchr15:91500733chr15:91326052ENST0000035511211221334_1349851.66666666666661418.0MotifNuclear localization signal
TgeneBLMchr15:91500954chr15:91328150ENST0000035511212221334_1349887.33333333333341418.0MotifNuclear localization signal
TgeneBLMchr15:91500955chr15:91328150ENST0000035511212221334_1349887.33333333333341418.0MotifNuclear localization signal
TgeneBLMchr15:91500955chr15:91328151ENST0000035511212221334_1349887.33333333333341418.0MotifNuclear localization signal
TgeneBLMchr15:91500733chr15:91326052ENST0000035511211221000_1003851.66666666666661418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500733chr15:91326052ENST0000035511211221094_1139851.66666666666661418.0RegionDNA Holliday junction binding
TgeneBLMchr15:91500733chr15:91326052ENST0000035511211221110_1112851.66666666666661418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500733chr15:91326052ENST0000035511211221121_1125851.66666666666661418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500733chr15:91326052ENST0000035511211221160_1166851.66666666666661418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500733chr15:91326052ENST0000035511211221227_1244851.66666666666661418.0RegionNecessary for ssDNA and DNA Holliday junction binding
TgeneBLMchr15:91500733chr15:91326052ENST000003551121122870_873851.66666666666661418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500733chr15:91326052ENST000003551121122897_899851.66666666666661418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500954chr15:91328150ENST0000035511212221000_1003887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500954chr15:91328150ENST0000035511212221094_1139887.33333333333341418.0RegionDNA Holliday junction binding
TgeneBLMchr15:91500954chr15:91328150ENST0000035511212221110_1112887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500954chr15:91328150ENST0000035511212221121_1125887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500954chr15:91328150ENST0000035511212221160_1166887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500954chr15:91328150ENST0000035511212221227_1244887.33333333333341418.0RegionNecessary for ssDNA and DNA Holliday junction binding
TgeneBLMchr15:91500954chr15:91328150ENST000003551121222897_899887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328150ENST0000035511212221000_1003887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328150ENST0000035511212221094_1139887.33333333333341418.0RegionDNA Holliday junction binding
TgeneBLMchr15:91500955chr15:91328150ENST0000035511212221110_1112887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328150ENST0000035511212221121_1125887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328150ENST0000035511212221160_1166887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328150ENST0000035511212221227_1244887.33333333333341418.0RegionNecessary for ssDNA and DNA Holliday junction binding
TgeneBLMchr15:91500955chr15:91328150ENST000003551121222897_899887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328151ENST0000035511212221000_1003887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328151ENST0000035511212221094_1139887.33333333333341418.0RegionDNA Holliday junction binding
TgeneBLMchr15:91500955chr15:91328151ENST0000035511212221110_1112887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328151ENST0000035511212221121_1125887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328151ENST0000035511212221160_1166887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328151ENST0000035511212221227_1244887.33333333333341418.0RegionNecessary for ssDNA and DNA Holliday junction binding
TgeneBLMchr15:91500955chr15:91328151ENST000003551121222897_899887.33333333333341418.0Region3' overhang DNA-binding

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRCCD1chr15:91500733chr15:91326052ENST00000394258+38176_227185.66666666666666377.0RepeatNote=RCC1 2
HgeneRCCD1chr15:91500733chr15:91326052ENST00000394258+38229_317185.66666666666666377.0RepeatNote=RCC1 3
HgeneRCCD1chr15:91500733chr15:91326052ENST00000394258+38318_371185.66666666666666377.0RepeatNote=RCC1 4
HgeneRCCD1chr15:91500733chr15:91326052ENST00000556618+39176_227185.66666666666666447.0RepeatNote=RCC1 2
HgeneRCCD1chr15:91500733chr15:91326052ENST00000556618+39229_317185.66666666666666447.0RepeatNote=RCC1 3
HgeneRCCD1chr15:91500733chr15:91326052ENST00000556618+39318_371185.66666666666666447.0RepeatNote=RCC1 4
HgeneRCCD1chr15:91500954chr15:91328150ENST00000394258+48229_317226.33333333333334377.0RepeatNote=RCC1 3
HgeneRCCD1chr15:91500954chr15:91328150ENST00000394258+48318_371226.33333333333334377.0RepeatNote=RCC1 4
HgeneRCCD1chr15:91500954chr15:91328150ENST00000556618+49229_317226.33333333333334447.0RepeatNote=RCC1 3
HgeneRCCD1chr15:91500954chr15:91328150ENST00000556618+49318_371226.33333333333334447.0RepeatNote=RCC1 4
HgeneRCCD1chr15:91500955chr15:91328150ENST00000394258+48229_317226.33333333333334377.0RepeatNote=RCC1 3
HgeneRCCD1chr15:91500955chr15:91328150ENST00000394258+48318_371226.33333333333334377.0RepeatNote=RCC1 4
HgeneRCCD1chr15:91500955chr15:91328150ENST00000556618+49229_317226.33333333333334447.0RepeatNote=RCC1 3
HgeneRCCD1chr15:91500955chr15:91328150ENST00000556618+49318_371226.33333333333334447.0RepeatNote=RCC1 4
HgeneRCCD1chr15:91500955chr15:91328151ENST00000394258+48229_317226.33333333333334377.0RepeatNote=RCC1 3
HgeneRCCD1chr15:91500955chr15:91328151ENST00000394258+48318_371226.33333333333334377.0RepeatNote=RCC1 4
HgeneRCCD1chr15:91500955chr15:91328151ENST00000556618+49229_317226.33333333333334447.0RepeatNote=RCC1 3
HgeneRCCD1chr15:91500955chr15:91328151ENST00000556618+49318_371226.33333333333334447.0RepeatNote=RCC1 4
TgeneBLMchr15:91500733chr15:91326052ENST000003551121122292_299851.66666666666661418.0Compositional biasNote=Poly-Asp
TgeneBLMchr15:91500733chr15:91326052ENST000003551121122310_316851.66666666666661418.0Compositional biasNote=Poly-Ser
TgeneBLMchr15:91500733chr15:91326052ENST000003551121122557_566851.66666666666661418.0Compositional biasNote=Poly-Asp
TgeneBLMchr15:91500954chr15:91328150ENST000003551121222292_299887.33333333333341418.0Compositional biasNote=Poly-Asp
TgeneBLMchr15:91500954chr15:91328150ENST000003551121222310_316887.33333333333341418.0Compositional biasNote=Poly-Ser
TgeneBLMchr15:91500954chr15:91328150ENST000003551121222557_566887.33333333333341418.0Compositional biasNote=Poly-Asp
TgeneBLMchr15:91500955chr15:91328150ENST000003551121222292_299887.33333333333341418.0Compositional biasNote=Poly-Asp
TgeneBLMchr15:91500955chr15:91328150ENST000003551121222310_316887.33333333333341418.0Compositional biasNote=Poly-Ser
TgeneBLMchr15:91500955chr15:91328150ENST000003551121222557_566887.33333333333341418.0Compositional biasNote=Poly-Asp
TgeneBLMchr15:91500955chr15:91328151ENST000003551121222292_299887.33333333333341418.0Compositional biasNote=Poly-Asp
TgeneBLMchr15:91500955chr15:91328151ENST000003551121222310_316887.33333333333341418.0Compositional biasNote=Poly-Ser
TgeneBLMchr15:91500955chr15:91328151ENST000003551121222557_566887.33333333333341418.0Compositional biasNote=Poly-Asp
TgeneBLMchr15:91500733chr15:91326052ENST000003551121122676_851851.66666666666661418.0DomainHelicase ATP-binding
TgeneBLMchr15:91500954chr15:91328150ENST000003551121222676_851887.33333333333341418.0DomainHelicase ATP-binding
TgeneBLMchr15:91500954chr15:91328150ENST000003551121222877_1024887.33333333333341418.0DomainHelicase C-terminal
TgeneBLMchr15:91500955chr15:91328150ENST000003551121222676_851887.33333333333341418.0DomainHelicase ATP-binding
TgeneBLMchr15:91500955chr15:91328150ENST000003551121222877_1024887.33333333333341418.0DomainHelicase C-terminal
TgeneBLMchr15:91500955chr15:91328151ENST000003551121222676_851887.33333333333341418.0DomainHelicase ATP-binding
TgeneBLMchr15:91500955chr15:91328151ENST000003551121222877_1024887.33333333333341418.0DomainHelicase C-terminal
TgeneBLMchr15:91500733chr15:91326052ENST000003551121122795_798851.66666666666661418.0MotifNote=DEAH box
TgeneBLMchr15:91500954chr15:91328150ENST000003551121222795_798887.33333333333341418.0MotifNote=DEAH box
TgeneBLMchr15:91500955chr15:91328150ENST000003551121222795_798887.33333333333341418.0MotifNote=DEAH box
TgeneBLMchr15:91500955chr15:91328151ENST000003551121222795_798887.33333333333341418.0MotifNote=DEAH box
TgeneBLMchr15:91500733chr15:91326052ENST000003551121122668_672851.66666666666661418.0Nucleotide bindingATP
TgeneBLMchr15:91500733chr15:91326052ENST000003551121122692_696851.66666666666661418.0Nucleotide bindingATP
TgeneBLMchr15:91500954chr15:91328150ENST000003551121222668_672887.33333333333341418.0Nucleotide bindingATP
TgeneBLMchr15:91500954chr15:91328150ENST000003551121222692_696887.33333333333341418.0Nucleotide bindingATP
TgeneBLMchr15:91500955chr15:91328150ENST000003551121222668_672887.33333333333341418.0Nucleotide bindingATP
TgeneBLMchr15:91500955chr15:91328150ENST000003551121222692_696887.33333333333341418.0Nucleotide bindingATP
TgeneBLMchr15:91500955chr15:91328151ENST000003551121222668_672887.33333333333341418.0Nucleotide bindingATP
TgeneBLMchr15:91500955chr15:91328151ENST000003551121222692_696887.33333333333341418.0Nucleotide bindingATP
TgeneBLMchr15:91500733chr15:91326052ENST000003551121122362_414851.66666666666661418.0RegionNecessary for dimerization and homooligomerization
TgeneBLMchr15:91500954chr15:91328150ENST000003551121222362_414887.33333333333341418.0RegionNecessary for dimerization and homooligomerization
TgeneBLMchr15:91500954chr15:91328150ENST000003551121222870_873887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328150ENST000003551121222362_414887.33333333333341418.0RegionNecessary for dimerization and homooligomerization
TgeneBLMchr15:91500955chr15:91328150ENST000003551121222870_873887.33333333333341418.0Region3' overhang DNA-binding
TgeneBLMchr15:91500955chr15:91328151ENST000003551121222362_414887.33333333333341418.0RegionNecessary for dimerization and homooligomerization
TgeneBLMchr15:91500955chr15:91328151ENST000003551121222870_873887.33333333333341418.0Region3' overhang DNA-binding


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
RCCD1
BLM


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to RCCD1-BLM


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to RCCD1-BLM


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource