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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:ATP11A-CUL4A

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: ATP11A-CUL4A
FusionPDB ID: 7709
FusionGDB2.0 ID: 7709
HgeneTgene
Gene symbol

ATP11A

CUL4A

Gene ID

23250

8451

Gene nameATPase phospholipid transporting 11Acullin 4A
SynonymsATPIH|ATPIS-
Cytomap

13q34

13q34

Type of geneprotein-codingprotein-coding
Descriptionprobable phospholipid-transporting ATPase IHATPase, class VI, type 11AP4-ATPase flippase complex alpha subunit ATP11Aphospholipid-translocating ATPasepotential phospholipid-transporting ATPase IHcullin-4ACUL-4A
Modification date2020031320200327
UniProtAcc

Q6ZP68

Q13619

Ensembl transtripts involved in fusion geneENST idsENST00000283558, ENST00000375630, 
ENST00000375645, ENST00000487903, 
ENST00000419448, 		ENST00000463426, 
ENST00000451881, ENST00000326335, 
ENST00000375440, ENST00000375441, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score20 X 11 X 16=352015 X 13 X 9=1755
# samples 3120
** MAII scorelog2(31/3520*10)=-3.50523530825042
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/1755*10)=-3.1333991254172
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: ATP11A [Title/Abstract] AND CUL4A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)ATP11A(113530255)-CUL4A(113917801), # samples:2
Anticipated loss of major functional domain due to fusion event.ATP11A-CUL4A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ATP11A-CUL4A seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ATP11A-CUL4A seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCUL4A

GO:0016567

protein ubiquitination

26431207


check buttonFusion gene breakpoints across ATP11A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CUL4A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-21-1081-01AATP11Achr13

113344768

+CUL4Achr13

113907395

+
ChimerDB4LUSCTCGA-21-1081ATP11Achr13

113344769

+CUL4Achr13

113907395

+
ChimerDB4LUSCTCGA-21-1081ATP11Achr13

113344769

+CUL4Achr13

113907396

+
ChimerDB4SKCMTCGA-EB-A5UL-06AATP11Achr13

113530255

+CUL4Achr13

113917801

+
ChimerDB4STADTCGA-EQ-8122-01AATP11Achr13

113530255

+CUL4Achr13

113917801

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000283558ATP11Achr13113344769+ENST00000375441CUL4Achr13113907395+76912755768238
ENST00000283558ATP11Achr13113344769+ENST00000451881CUL4Achr13113907395+226412755768237
ENST00000283558ATP11Achr13113344769+ENST00000326335CUL4Achr13113907395+227212755768237
ENST00000283558ATP11Achr13113344769+ENST00000375440CUL4Achr13113907395+76912755768238
ENST00000375630ATP11Achr13113344769+ENST00000375441CUL4Achr13113907395+76912755768238
ENST00000375630ATP11Achr13113344769+ENST00000451881CUL4Achr13113907395+226412755768237
ENST00000375630ATP11Achr13113344769+ENST00000326335CUL4Achr13113907395+227212755768237
ENST00000375630ATP11Achr13113344769+ENST00000375440CUL4Achr13113907395+76912755768238
ENST00000487903ATP11Achr13113344769+ENST00000375441CUL4Achr13113907395+76912755768238
ENST00000487903ATP11Achr13113344769+ENST00000451881CUL4Achr13113907395+226412755768237
ENST00000487903ATP11Achr13113344769+ENST00000326335CUL4Achr13113907395+227212755768237
ENST00000487903ATP11Achr13113344769+ENST00000375440CUL4Achr13113907395+76912755768238
ENST00000375645ATP11Achr13113344769+ENST00000375441CUL4Achr13113907395+76912755768238
ENST00000375645ATP11Achr13113344769+ENST00000451881CUL4Achr13113907395+226412755768237
ENST00000375645ATP11Achr13113344769+ENST00000326335CUL4Achr13113907395+227212755768237
ENST00000375645ATP11Achr13113344769+ENST00000375440CUL4Achr13113907395+76912755768238
ENST00000283558ATP11Achr13113344769+ENST00000375441CUL4Achr13113907396+76912755768238
ENST00000283558ATP11Achr13113344769+ENST00000451881CUL4Achr13113907396+226412755768237
ENST00000283558ATP11Achr13113344769+ENST00000326335CUL4Achr13113907396+227212755768237
ENST00000283558ATP11Achr13113344769+ENST00000375440CUL4Achr13113907396+76912755768238
ENST00000375630ATP11Achr13113344769+ENST00000375441CUL4Achr13113907396+76912755768238
ENST00000375630ATP11Achr13113344769+ENST00000451881CUL4Achr13113907396+226412755768237
ENST00000375630ATP11Achr13113344769+ENST00000326335CUL4Achr13113907396+227212755768237
ENST00000375630ATP11Achr13113344769+ENST00000375440CUL4Achr13113907396+76912755768238
ENST00000487903ATP11Achr13113344769+ENST00000375441CUL4Achr13113907396+76912755768238
ENST00000487903ATP11Achr13113344769+ENST00000451881CUL4Achr13113907396+226412755768237
ENST00000487903ATP11Achr13113344769+ENST00000326335CUL4Achr13113907396+227212755768237
ENST00000487903ATP11Achr13113344769+ENST00000375440CUL4Achr13113907396+76912755768238
ENST00000375645ATP11Achr13113344769+ENST00000375441CUL4Achr13113907396+76912755768238
ENST00000375645ATP11Achr13113344769+ENST00000451881CUL4Achr13113907396+226412755768237
ENST00000375645ATP11Achr13113344769+ENST00000326335CUL4Achr13113907396+227212755768237
ENST00000375645ATP11Achr13113344769+ENST00000375440CUL4Achr13113907396+76912755768238
ENST00000283558ATP11Achr13113530255+ENST00000375441CUL4Achr13113917801+351134155535101152
ENST00000283558ATP11Achr13113530255+ENST00000326335CUL4Achr13113917801+501434155535101151
ENST00000283558ATP11Achr13113530255+ENST00000375440CUL4Achr13113917801+351134155535101152
ENST00000375630ATP11Achr13113530255+ENST00000375441CUL4Achr13113917801+351134155535101152
ENST00000375630ATP11Achr13113530255+ENST00000326335CUL4Achr13113917801+501434155535101151
ENST00000375630ATP11Achr13113530255+ENST00000375440CUL4Achr13113917801+351134155535101152
ENST00000487903ATP11Achr13113530255+ENST00000375441CUL4Achr13113917801+351134155535101152
ENST00000487903ATP11Achr13113530255+ENST00000326335CUL4Achr13113917801+501434155535101151
ENST00000487903ATP11Achr13113530255+ENST00000375440CUL4Achr13113917801+351134155535101152
ENST00000375645ATP11Achr13113530255+ENST00000375441CUL4Achr13113917801+351134155535101152
ENST00000375645ATP11Achr13113530255+ENST00000326335CUL4Achr13113917801+501434155535101151
ENST00000375645ATP11Achr13113530255+ENST00000375440CUL4Achr13113917801+351134155535101152
ENST00000283558ATP11Achr13113344768+ENST00000375441CUL4Achr13113907395+76912755768238
ENST00000283558ATP11Achr13113344768+ENST00000451881CUL4Achr13113907395+226412755768237
ENST00000283558ATP11Achr13113344768+ENST00000326335CUL4Achr13113907395+227212755768237
ENST00000283558ATP11Achr13113344768+ENST00000375440CUL4Achr13113907395+76912755768238
ENST00000375630ATP11Achr13113344768+ENST00000375441CUL4Achr13113907395+76912755768238
ENST00000375630ATP11Achr13113344768+ENST00000451881CUL4Achr13113907395+226412755768237
ENST00000375630ATP11Achr13113344768+ENST00000326335CUL4Achr13113907395+227212755768237
ENST00000375630ATP11Achr13113344768+ENST00000375440CUL4Achr13113907395+76912755768238
ENST00000487903ATP11Achr13113344768+ENST00000375441CUL4Achr13113907395+76912755768238
ENST00000487903ATP11Achr13113344768+ENST00000451881CUL4Achr13113907395+226412755768237
ENST00000487903ATP11Achr13113344768+ENST00000326335CUL4Achr13113907395+227212755768237
ENST00000487903ATP11Achr13113344768+ENST00000375440CUL4Achr13113907395+76912755768238
ENST00000375645ATP11Achr13113344768+ENST00000375441CUL4Achr13113907395+76912755768238
ENST00000375645ATP11Achr13113344768+ENST00000451881CUL4Achr13113907395+226412755768237
ENST00000375645ATP11Achr13113344768+ENST00000326335CUL4Achr13113907395+227212755768237
ENST00000375645ATP11Achr13113344768+ENST00000375440CUL4Achr13113907395+76912755768238

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000283558ENST00000375441ATP11Achr13113344769+CUL4Achr13113907395+0.0013168170.99868315
ENST00000283558ENST00000451881ATP11Achr13113344769+CUL4Achr13113907395+0.0003325810.9996674
ENST00000283558ENST00000326335ATP11Achr13113344769+CUL4Achr13113907395+0.0003273230.99967265
ENST00000283558ENST00000375440ATP11Achr13113344769+CUL4Achr13113907395+0.0013168170.99868315
ENST00000375630ENST00000375441ATP11Achr13113344769+CUL4Achr13113907395+0.0013168170.99868315
ENST00000375630ENST00000451881ATP11Achr13113344769+CUL4Achr13113907395+0.0003325810.9996674
ENST00000375630ENST00000326335ATP11Achr13113344769+CUL4Achr13113907395+0.0003273230.99967265
ENST00000375630ENST00000375440ATP11Achr13113344769+CUL4Achr13113907395+0.0013168170.99868315
ENST00000487903ENST00000375441ATP11Achr13113344769+CUL4Achr13113907395+0.0013168170.99868315
ENST00000487903ENST00000451881ATP11Achr13113344769+CUL4Achr13113907395+0.0003325810.9996674
ENST00000487903ENST00000326335ATP11Achr13113344769+CUL4Achr13113907395+0.0003273230.99967265
ENST00000487903ENST00000375440ATP11Achr13113344769+CUL4Achr13113907395+0.0013168170.99868315
ENST00000375645ENST00000375441ATP11Achr13113344769+CUL4Achr13113907395+0.0013168170.99868315
ENST00000375645ENST00000451881ATP11Achr13113344769+CUL4Achr13113907395+0.0003325810.9996674
ENST00000375645ENST00000326335ATP11Achr13113344769+CUL4Achr13113907395+0.0003273230.99967265
ENST00000375645ENST00000375440ATP11Achr13113344769+CUL4Achr13113907395+0.0013168170.99868315
ENST00000283558ENST00000375441ATP11Achr13113344769+CUL4Achr13113907396+0.0013168170.99868315
ENST00000283558ENST00000451881ATP11Achr13113344769+CUL4Achr13113907396+0.0003325810.9996674
ENST00000283558ENST00000326335ATP11Achr13113344769+CUL4Achr13113907396+0.0003273230.99967265
ENST00000283558ENST00000375440ATP11Achr13113344769+CUL4Achr13113907396+0.0013168170.99868315
ENST00000375630ENST00000375441ATP11Achr13113344769+CUL4Achr13113907396+0.0013168170.99868315
ENST00000375630ENST00000451881ATP11Achr13113344769+CUL4Achr13113907396+0.0003325810.9996674
ENST00000375630ENST00000326335ATP11Achr13113344769+CUL4Achr13113907396+0.0003273230.99967265
ENST00000375630ENST00000375440ATP11Achr13113344769+CUL4Achr13113907396+0.0013168170.99868315
ENST00000487903ENST00000375441ATP11Achr13113344769+CUL4Achr13113907396+0.0013168170.99868315
ENST00000487903ENST00000451881ATP11Achr13113344769+CUL4Achr13113907396+0.0003325810.9996674
ENST00000487903ENST00000326335ATP11Achr13113344769+CUL4Achr13113907396+0.0003273230.99967265
ENST00000487903ENST00000375440ATP11Achr13113344769+CUL4Achr13113907396+0.0013168170.99868315
ENST00000375645ENST00000375441ATP11Achr13113344769+CUL4Achr13113907396+0.0013168170.99868315
ENST00000375645ENST00000451881ATP11Achr13113344769+CUL4Achr13113907396+0.0003325810.9996674
ENST00000375645ENST00000326335ATP11Achr13113344769+CUL4Achr13113907396+0.0003273230.99967265
ENST00000375645ENST00000375440ATP11Achr13113344769+CUL4Achr13113907396+0.0013168170.99868315
ENST00000283558ENST00000375441ATP11Achr13113530255+CUL4Achr13113917801+0.0007591080.9992409
ENST00000283558ENST00000326335ATP11Achr13113530255+CUL4Achr13113917801+0.0002030210.99979705
ENST00000283558ENST00000375440ATP11Achr13113530255+CUL4Achr13113917801+0.0007591080.9992409
ENST00000375630ENST00000375441ATP11Achr13113530255+CUL4Achr13113917801+0.0007591080.9992409
ENST00000375630ENST00000326335ATP11Achr13113530255+CUL4Achr13113917801+0.0002030210.99979705
ENST00000375630ENST00000375440ATP11Achr13113530255+CUL4Achr13113917801+0.0007591080.9992409
ENST00000487903ENST00000375441ATP11Achr13113530255+CUL4Achr13113917801+0.0007591080.9992409
ENST00000487903ENST00000326335ATP11Achr13113530255+CUL4Achr13113917801+0.0002030210.99979705
ENST00000487903ENST00000375440ATP11Achr13113530255+CUL4Achr13113917801+0.0007591080.9992409
ENST00000375645ENST00000375441ATP11Achr13113530255+CUL4Achr13113917801+0.0007591080.9992409
ENST00000375645ENST00000326335ATP11Achr13113530255+CUL4Achr13113917801+0.0002030210.99979705
ENST00000375645ENST00000375440ATP11Achr13113530255+CUL4Achr13113917801+0.0007591080.9992409
ENST00000283558ENST00000375441ATP11Achr13113344768+CUL4Achr13113907395+0.0013168170.99868315
ENST00000283558ENST00000451881ATP11Achr13113344768+CUL4Achr13113907395+0.0003325810.9996674
ENST00000283558ENST00000326335ATP11Achr13113344768+CUL4Achr13113907395+0.0003273230.99967265
ENST00000283558ENST00000375440ATP11Achr13113344768+CUL4Achr13113907395+0.0013168170.99868315
ENST00000375630ENST00000375441ATP11Achr13113344768+CUL4Achr13113907395+0.0013168170.99868315
ENST00000375630ENST00000451881ATP11Achr13113344768+CUL4Achr13113907395+0.0003325810.9996674
ENST00000375630ENST00000326335ATP11Achr13113344768+CUL4Achr13113907395+0.0003273230.99967265
ENST00000375630ENST00000375440ATP11Achr13113344768+CUL4Achr13113907395+0.0013168170.99868315
ENST00000487903ENST00000375441ATP11Achr13113344768+CUL4Achr13113907395+0.0013168170.99868315
ENST00000487903ENST00000451881ATP11Achr13113344768+CUL4Achr13113907395+0.0003325810.9996674
ENST00000487903ENST00000326335ATP11Achr13113344768+CUL4Achr13113907395+0.0003273230.99967265
ENST00000487903ENST00000375440ATP11Achr13113344768+CUL4Achr13113907395+0.0013168170.99868315
ENST00000375645ENST00000375441ATP11Achr13113344768+CUL4Achr13113907395+0.0013168170.99868315
ENST00000375645ENST00000451881ATP11Achr13113344768+CUL4Achr13113907395+0.0003325810.9996674
ENST00000375645ENST00000326335ATP11Achr13113344768+CUL4Achr13113907395+0.0003273230.99967265
ENST00000375645ENST00000375440ATP11Achr13113344768+CUL4Achr13113907395+0.0013168170.99868315

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>7709_7709_1_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000283558_CUL4A_chr13_113907395_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_2_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000283558_CUL4A_chr13_113907395_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_3_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000283558_CUL4A_chr13_113907395_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_4_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000283558_CUL4A_chr13_113907395_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_5_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000375630_CUL4A_chr13_113907395_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_6_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000375630_CUL4A_chr13_113907395_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_7_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000375630_CUL4A_chr13_113907395_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_8_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000375630_CUL4A_chr13_113907395_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_9_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000375645_CUL4A_chr13_113907395_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_10_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000375645_CUL4A_chr13_113907395_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_11_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000375645_CUL4A_chr13_113907395_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_12_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000375645_CUL4A_chr13_113907395_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_13_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000487903_CUL4A_chr13_113907395_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_14_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000487903_CUL4A_chr13_113907395_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_15_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000487903_CUL4A_chr13_113907395_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_16_ATP11A-CUL4A_ATP11A_chr13_113344768_ENST00000487903_CUL4A_chr13_113907395_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_17_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000283558_CUL4A_chr13_113907395_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_18_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000283558_CUL4A_chr13_113907395_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_19_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000283558_CUL4A_chr13_113907395_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_20_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000283558_CUL4A_chr13_113907395_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_21_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000283558_CUL4A_chr13_113907396_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_22_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000283558_CUL4A_chr13_113907396_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_23_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000283558_CUL4A_chr13_113907396_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_24_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000283558_CUL4A_chr13_113907396_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_25_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375630_CUL4A_chr13_113907395_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_26_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375630_CUL4A_chr13_113907395_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_27_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375630_CUL4A_chr13_113907395_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_28_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375630_CUL4A_chr13_113907395_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_29_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375630_CUL4A_chr13_113907396_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_30_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375630_CUL4A_chr13_113907396_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_31_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375630_CUL4A_chr13_113907396_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_32_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375630_CUL4A_chr13_113907396_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_33_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375645_CUL4A_chr13_113907395_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_34_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375645_CUL4A_chr13_113907395_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_35_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375645_CUL4A_chr13_113907395_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_36_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375645_CUL4A_chr13_113907395_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_37_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375645_CUL4A_chr13_113907396_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_38_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375645_CUL4A_chr13_113907396_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_39_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375645_CUL4A_chr13_113907396_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_40_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000375645_CUL4A_chr13_113907396_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_41_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000487903_CUL4A_chr13_113907395_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_42_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000487903_CUL4A_chr13_113907395_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_43_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000487903_CUL4A_chr13_113907395_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_44_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000487903_CUL4A_chr13_113907395_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_45_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000487903_CUL4A_chr13_113907396_ENST00000326335_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_46_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000487903_CUL4A_chr13_113907396_ENST00000375440_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_47_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000487903_CUL4A_chr13_113907396_ENST00000375441_length(amino acids)=238AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_48_ATP11A-CUL4A_ATP11A_chr13_113344769_ENST00000487903_CUL4A_chr13_113907396_ENST00000451881_length(amino acids)=237AA_BP=24
MNGGAGAAGGAMDCSLVRTLVHRYMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEE
IKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVR

--------------------------------------------------------------

>7709_7709_49_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000283558_CUL4A_chr13_113917801_ENST00000326335_length(amino acids)=1151AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

--------------------------------------------------------------

>7709_7709_50_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000283558_CUL4A_chr13_113917801_ENST00000375440_length(amino acids)=1152AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

--------------------------------------------------------------

>7709_7709_51_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000283558_CUL4A_chr13_113917801_ENST00000375441_length(amino acids)=1152AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

--------------------------------------------------------------

>7709_7709_52_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000375630_CUL4A_chr13_113917801_ENST00000326335_length(amino acids)=1151AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

--------------------------------------------------------------

>7709_7709_53_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000375630_CUL4A_chr13_113917801_ENST00000375440_length(amino acids)=1152AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

--------------------------------------------------------------

>7709_7709_54_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000375630_CUL4A_chr13_113917801_ENST00000375441_length(amino acids)=1152AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

--------------------------------------------------------------

>7709_7709_55_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000375645_CUL4A_chr13_113917801_ENST00000326335_length(amino acids)=1151AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

--------------------------------------------------------------

>7709_7709_56_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000375645_CUL4A_chr13_113917801_ENST00000375440_length(amino acids)=1152AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

--------------------------------------------------------------

>7709_7709_57_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000375645_CUL4A_chr13_113917801_ENST00000375441_length(amino acids)=1152AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

--------------------------------------------------------------

>7709_7709_58_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000487903_CUL4A_chr13_113917801_ENST00000326335_length(amino acids)=1151AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

--------------------------------------------------------------

>7709_7709_59_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000487903_CUL4A_chr13_113917801_ENST00000375440_length(amino acids)=1152AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

--------------------------------------------------------------

>7709_7709_60_ATP11A-CUL4A_ATP11A_chr13_113530255_ENST00000487903_CUL4A_chr13_113917801_ENST00000375441_length(amino acids)=1152AA_BP=1
MNGGAGAAGGAMDCSLVRTLVHRYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLI
IFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSS
NRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNT
EKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDF
LAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPH
VICNGQVLPESSGIDMIDSSPSVNGREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLK
DNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE
EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQ
LLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRM
APLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYK
NVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVF
FFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQM

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:113530255/chr13:113917801)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
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6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATP11A

Q6ZP68

CUL4A

Q13619

FUNCTION: Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. DCX(DET1-COP1) directs ubiquitination of JUN. DCX(DDB2) directs ubiquitination of XPC. DCX(DDB2) ubiquitinates histones H3-H4 and is required for efficient histone deposition during replication-coupled (H3.1) and replication-independent (H3.3) nucleosome assembly, probably by facilitating the transfer of H3 from ASF1A/ASF1B to other chaperones involved in histone deposition. DCX(DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitination of TP53 in response to radiation-induced DNA damage and during DNA replication. In association with DDB1 and SKP2 probably is involved in ubiquitination of CDKN1B/p27kip. Is involved in ubiquitination of HOXA9. DCX(DTL) directs autoubiquitination of DTL. The DDB1-CUL4A-DTL E3 ligase complex regulates the circadian clock function by mediating the ubiquitination and degradation of CRY1 (PubMed:26431207). With CUL4B, contributes to ribosome biogenesis (PubMed:26711351). {ECO:0000269|PubMed:14578910, ECO:0000269|PubMed:14609952, ECO:0000269|PubMed:15448697, ECO:0000269|PubMed:15548678, ECO:0000269|PubMed:16537899, ECO:0000269|PubMed:16678110, ECO:0000269|PubMed:23478445, ECO:0000269|PubMed:24209620, ECO:0000269|PubMed:26431207, ECO:0000269|PubMed:26711351}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+28291024_10291109.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+28291051_10681109.01135.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+2829111_2961109.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+28291_611109.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+2829319_3491109.01135.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+2829373_8811109.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+282983_881109.01135.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+2829903_9141109.01135.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+2829935_9641109.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+2829987_10001109.01135.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+28301024_10291109.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+28301051_10681109.02857.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+2830111_2961109.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+28301_611109.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+2830319_3491109.02857.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+2830373_8811109.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+283083_881109.02857.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+2830903_9141109.02857.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+2830935_9641109.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+2830987_10001109.02857.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+28301024_10291109.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+28301051_10681109.02878.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+2830111_2961109.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+28301_611109.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+2830319_3491109.02878.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+2830373_8811109.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+283083_881109.02878.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+2830903_9141109.02878.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+2830935_9641109.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+2830987_10001109.02878.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+28291001_10231109.01135.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+28291030_10501109.01135.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+28291069_10931109.01135.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+2829297_3181109.01135.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+2829350_3721109.01135.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+282962_821109.01135.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+2829882_9021109.01135.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+282989_1101109.01135.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+2829915_9341109.01135.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+2829965_9861109.01135.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+28301001_10231109.02857.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+28301030_10501109.02857.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+28301069_10931109.02857.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+2830297_3181109.02857.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+2830350_3721109.02857.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+283062_821109.02857.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+2830882_9021109.02857.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+283089_1101109.02857.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+2830915_9341109.02857.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+2830965_9861109.02857.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+28301001_10231109.02878.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+28301030_10501109.02878.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+28301069_10931109.02878.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+2830297_3181109.02878.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+2830350_3721109.02878.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+283062_821109.02878.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+2830882_9021109.02878.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+283089_1101109.02878.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+2830915_9341109.02878.0TransmembraneHelical
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+2830965_9861109.02878.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+1291024_102913.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+1291051_106813.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+1291094_113413.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+129111_29613.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+1291_6113.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+129319_34913.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+129373_88113.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+12983_8813.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+129903_91413.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+129935_96413.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+129987_100013.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+1301024_102913.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+1301051_106813.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+1301094_113413.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+130111_29613.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+1301_6113.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+130319_34913.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+130373_88113.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+13083_8813.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+130903_91413.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+130935_96413.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+130987_100013.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+1301024_102913.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+1301051_106813.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+1301094_113413.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+130111_29613.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+1301_6113.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+130319_34913.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+130373_88113.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+13083_8813.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+130903_91413.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+130935_96413.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+130987_100013.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+1291024_102913.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+1291051_106813.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+1291094_113413.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+129111_29613.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+1291_6113.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+129319_34913.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+129373_88113.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+12983_8813.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+129903_91413.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+129935_96413.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+129987_100013.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+1301024_102913.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+1301051_106813.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+1301094_113413.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+130111_29613.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+1301_6113.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+130319_34913.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+130373_88113.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+13083_8813.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+130903_91413.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+130935_96413.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+130987_100013.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+1301024_102913.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+1301051_106813.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+1301094_113413.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+130111_29613.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+1301_6113.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+130319_34913.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+130373_88113.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+13083_8813.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+130903_91413.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+130935_96413.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+130987_100013.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+1291024_102913.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+1291051_106813.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+1291094_113413.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+129111_29613.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+1291_6113.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+129319_34913.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+129373_88113.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+12983_8813.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+129903_91413.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+129935_96413.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+129987_100013.01135.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+1301024_102913.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+1301051_106813.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+1301094_113413.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+130111_29613.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+1301_6113.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+130319_34913.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+130373_88113.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+13083_8813.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+130903_91413.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+130935_96413.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+130987_100013.02857.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+1301024_102913.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+1301051_106813.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+1301094_113413.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+130111_29613.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+1301_6113.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+130319_34913.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+130373_88113.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+13083_8813.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+130903_91413.02878.0Topological domainExtracellular
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+130935_96413.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+130987_100013.02878.0Topological domainExtracellular
HgeneATP11Achr13:113530255chr13:113917801ENST00000283558+28291094_11341109.01135.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000375645+28301094_11341109.02857.0Topological domainCytoplasmic
HgeneATP11Achr13:113530255chr13:113917801ENST00000487903+28301094_11341109.02878.0Topological domainCytoplasmic
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+1291001_102313.01135.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+1291030_105013.01135.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+1291069_109313.01135.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+129297_31813.01135.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+129350_37213.01135.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+12962_8213.01135.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+129882_90213.01135.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+12989_11013.01135.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+129915_93413.01135.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000283558+129965_98613.01135.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+1301001_102313.02857.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+1301030_105013.02857.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+1301069_109313.02857.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+130297_31813.02857.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+130350_37213.02857.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+13062_8213.02857.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+130882_90213.02857.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+13089_11013.02857.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+130915_93413.02857.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000375645+130965_98613.02857.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+1301001_102313.02878.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+1301030_105013.02878.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+1301069_109313.02878.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+130297_31813.02878.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+130350_37213.02878.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+13062_8213.02878.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+130882_90213.02878.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+13089_11013.02878.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+130915_93413.02878.0TransmembraneHelical
HgeneATP11Achr13:113344768chr13:113907395ENST00000487903+130965_98613.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+1291001_102313.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+1291030_105013.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+1291069_109313.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+129297_31813.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+129350_37213.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+12962_8213.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+129882_90213.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+12989_11013.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+129915_93413.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000283558+129965_98613.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+1301001_102313.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+1301030_105013.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+1301069_109313.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+130297_31813.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+130350_37213.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+13062_8213.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+130882_90213.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+13089_11013.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+130915_93413.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000375645+130965_98613.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+1301001_102313.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+1301030_105013.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+1301069_109313.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+130297_31813.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+130350_37213.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+13062_8213.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+130882_90213.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+13089_11013.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+130915_93413.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907395ENST00000487903+130965_98613.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+1291001_102313.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+1291030_105013.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+1291069_109313.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+129297_31813.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+129350_37213.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+12962_8213.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+129882_90213.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+12989_11013.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+129915_93413.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000283558+129965_98613.01135.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+1301001_102313.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+1301030_105013.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+1301069_109313.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+130297_31813.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+130350_37213.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+13062_8213.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+130882_90213.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+13089_11013.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+130915_93413.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000375645+130965_98613.02857.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+1301001_102313.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+1301030_105013.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+1301069_109313.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+130297_31813.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+130350_37213.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+13062_8213.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+130882_90213.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+13089_11013.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+130915_93413.02878.0TransmembraneHelical
HgeneATP11Achr13:113344769chr13:113907396ENST00000487903+130965_98613.02878.0TransmembraneHelical


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
ATP11A_pLDDT.png
all structure
all structure
CUL4A_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
ATP11A
CUL4A


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to ATP11A-CUL4A


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to ATP11A-CUL4A


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource