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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:ATP2C1-TMEM241

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: ATP2C1-TMEM241
FusionPDB ID: 7897
FusionGDB2.0 ID: 7897
HgeneTgene
Gene symbol

ATP2C1

TMEM241

Gene ID

27032

85019

Gene nameATPase secretory pathway Ca2+ transporting 1transmembrane protein 241
SynonymsATP2C1A|BCPM|HHD|PMR1|SPCA1|hSPCA1C18orf45|hVVT
Cytomap

3q22.1

18q11.2

Type of geneprotein-codingprotein-coding
Descriptioncalcium-transporting ATPase type 2C member 1ATP-dependent Ca(2+) pump PMR1ATPase 2C1ATPase, Ca(2+)-sequesteringATPase, Ca++ transporting, type 2C, member 1HUSSY-28secretory pathway Ca2+/Mn2+ ATPase 1transmembrane protein 241putative vertebrate vrg4-like nucleotide-sugar transporter truncated variant2putative vertebrate vrg4-like nucleotide-sugar transporter variant1transmembrane protein C18orf45
Modification date2020031320200313
UniProtAcc

P98194

Q24JQ0

Ensembl transtripts involved in fusion geneENST idsENST00000328560, ENST00000359644, 
ENST00000393221, ENST00000422190, 
ENST00000428331, ENST00000504381, 
ENST00000504948, ENST00000505330, 
ENST00000507488, ENST00000508532, 
ENST00000510168, ENST00000513801, 
ENST00000533801, ENST00000509150, 
ENST00000542162, ENST00000475185, 
ENST00000399707, ENST00000383233, 
ENST00000450466, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score16 X 17 X 10=27209 X 8 X 6=432
# samples 1911
** MAII scorelog2(19/2720*10)=-3.83953532780675
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/432*10)=-1.97352778863881
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: ATP2C1 [Title/Abstract] AND TMEM241 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)ATP2C1(130660543)-TMEM241(20889708), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneATP2C1

GO:0006816

calcium ion transport

12810057

HgeneATP2C1

GO:0006874

cellular calcium ion homeostasis

12810057


check buttonFusion gene breakpoints across ATP2C1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TMEM241 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-3B-A9HS-01AATP2C1chr3

130660543

+TMEM241chr18

20889708

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000505330ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-1385859226924232
ENST00000505330ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-2975859226984252
ENST00000504381ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-1268742226807193
ENST00000504381ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-2858742226867213
ENST00000507488ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-1379853220918232
ENST00000507488ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-2969853220978252
ENST00000393221ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-1374848215913232
ENST00000393221ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-2964848215973252
ENST00000533801ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-109456852633193
ENST00000533801ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-268456852693213
ENST00000510168ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-160710815501146198
ENST00000510168ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-319710815501206218
ENST00000508532ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-14669404091005198
ENST00000508532ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-30569404091065218
ENST00000504948ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-1211685118750210
ENST00000504948ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-2801685118810230
ENST00000513801ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-1211685118750210
ENST00000513801ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-2801685118810230
ENST00000328560ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-1379853322918198
ENST00000328560ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-2969853322978218
ENST00000428331ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-1292766235831198
ENST00000428331ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-2882766235891218
ENST00000359644ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-1186660129725198
ENST00000359644ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-2776660129785218
ENST00000422190ATP2C1chr3130660543+ENST00000450466TMEM241chr1820889708-1186660129725198
ENST00000422190ATP2C1chr3130660543+ENST00000383233TMEM241chr1820889708-2776660129785218

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000505330ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0005326670.9994673
ENST00000505330ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.001225230.9987747
ENST00000504381ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0004494390.9995505
ENST00000504381ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.0008319890.99916804
ENST00000507488ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0006039740.99939597
ENST00000507488ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.0012238950.99877614
ENST00000393221ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.000577820.9994222
ENST00000393221ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.00130570.99869436
ENST00000533801ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0004074880.9995925
ENST00000533801ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.0008300320.99916995
ENST00000510168ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0041159350.995884
ENST00000510168ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.0024336120.99756646
ENST00000508532ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0034519450.9965481
ENST00000508532ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.0022880680.9977119
ENST00000504948ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0021934550.9978066
ENST00000504948ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.0022504870.9977495
ENST00000513801ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0021934550.9978066
ENST00000513801ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.0022504870.9977495
ENST00000328560ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0016184320.9983816
ENST00000328560ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.0016060.99839395
ENST00000428331ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0011456250.9988544
ENST00000428331ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.0015901660.99840975
ENST00000359644ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0009870360.99901295
ENST00000359644ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.0017044680.9982955
ENST00000422190ENST00000450466ATP2C1chr3130660543+TMEM241chr1820889708-0.0009870360.99901295
ENST00000422190ENST00000383233ATP2C1chr3130660543+TMEM241chr1820889708-0.0017044680.9982955

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>7897_7897_1_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000328560_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=218AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_2_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000328560_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=198AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_3_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000359644_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=218AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_4_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000359644_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=198AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_5_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000393221_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=252AA_BP=211
MDSLLPPSRFSYFKKYPLHAIRRYLSTLRNQRAEEQVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRA
FHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGK

--------------------------------------------------------------

>7897_7897_6_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000393221_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=232AA_BP=211
MDSLLPPSRFSYFKKYPLHAIRRYLSTLRNQRAEEQVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRA
FHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGK

--------------------------------------------------------------

>7897_7897_7_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000422190_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=218AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_8_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000422190_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=198AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_9_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000428331_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=218AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_10_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000428331_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=198AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_11_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000504381_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=213AA_BP=172
MDSLLPPSRFSYFKKYPLHAIRRYLSTLRNQRAEEQVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQFKNPLIMLLLASAVISV
LMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIITAGLSI

--------------------------------------------------------------

>7897_7897_12_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000504381_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=193AA_BP=172
MDSLLPPSRFSYFKKYPLHAIRRYLSTLRNQRAEEQVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQFKNPLIMLLLASAVISV
LMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIITAGLSI

--------------------------------------------------------------

>7897_7897_13_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000504948_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=230AA_BP=189
MRPRSLEEGCPGLWVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQ
FKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDR

--------------------------------------------------------------

>7897_7897_14_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000504948_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=210AA_BP=189
MRPRSLEEGCPGLWVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQ
FKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDR

--------------------------------------------------------------

>7897_7897_15_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000505330_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=252AA_BP=211
MDSLLPPSRFSYFKKYPLHAIRRYLSTLRNQRAEEQVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRA
FHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGK

--------------------------------------------------------------

>7897_7897_16_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000505330_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=232AA_BP=211
MDSLLPPSRFSYFKKYPLHAIRRYLSTLRNQRAEEQVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRA
FHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGK

--------------------------------------------------------------

>7897_7897_17_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000507488_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=252AA_BP=211
MDSLLPPSRFSYFKKYPLHAIRRYLSTLRNQRAEEQVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRA
FHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGK

--------------------------------------------------------------

>7897_7897_18_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000507488_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=232AA_BP=211
MDSLLPPSRFSYFKKYPLHAIRRYLSTLRNQRAEEQVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRA
FHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGK

--------------------------------------------------------------

>7897_7897_19_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000508532_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=218AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_20_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000508532_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=198AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_21_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000510168_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=218AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_22_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000510168_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=198AA_BP=177
MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS
AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIIT

--------------------------------------------------------------

>7897_7897_23_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000513801_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=230AA_BP=189
MRPRSLEEGCPGLWVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQ
FKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDR

--------------------------------------------------------------

>7897_7897_24_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000513801_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=210AA_BP=189
MRPRSLEEGCPGLWVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQ
FKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDR

--------------------------------------------------------------

>7897_7897_25_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000533801_TMEM241_chr18_20889708_ENST00000383233_length(amino acids)=213AA_BP=172
MDSLLPPSRFSYFKKYPLHAIRRYLSTLRNQRAEEQVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQFKNPLIMLLLASAVISV
LMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIITAGLSI

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>7897_7897_26_ATP2C1-TMEM241_ATP2C1_chr3_130660543_ENST00000533801_TMEM241_chr18_20889708_ENST00000450466_length(amino acids)=193AA_BP=172
MDSLLPPSRFSYFKKYPLHAIRRYLSTLRNQRAEEQVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQFKNPLIMLLLASAVISV
LMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEIITAGLSI

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:130660543/chr18:20889708)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATP2C1

P98194

TMEM241

Q24JQ0

FUNCTION: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+7271_70177.0889.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+72792_104177.0889.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+7281_70177.0950.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+72892_104177.0950.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+7281_70211.0974.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+72892_104211.0974.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+7281_70177.0940.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+72892_104177.0940.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+7271_70177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+72792_104177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+7271_70161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+72792_104161.0904.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+7271_70161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+72792_104161.0904.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+7281_70161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+72892_104161.0924.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+8281_70177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+82892_104177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+8281_70177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+82892_104177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+7281_70161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+72892_104161.0924.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727105_123177.0889.0TransmembraneHelical%3B Name%3D2
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+72771_91177.0889.0TransmembraneHelical%3B Name%3D1
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728105_123177.0950.0TransmembraneHelical%3B Name%3D2
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+72871_91177.0950.0TransmembraneHelical%3B Name%3D1
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728105_123211.0974.0TransmembraneHelical%3B Name%3D2
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+72871_91211.0974.0TransmembraneHelical%3B Name%3D1
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728105_123177.0940.0TransmembraneHelical%3B Name%3D2
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+72871_91177.0940.0TransmembraneHelical%3B Name%3D1
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727105_123177.0920.0TransmembraneHelical%3B Name%3D2
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+72771_91177.0920.0TransmembraneHelical%3B Name%3D1
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727105_123161.0904.0TransmembraneHelical%3B Name%3D2
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+72771_91161.0904.0TransmembraneHelical%3B Name%3D1
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727105_123161.0904.0TransmembraneHelical%3B Name%3D2
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+72771_91161.0904.0TransmembraneHelical%3B Name%3D1
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728105_123161.0924.0TransmembraneHelical%3B Name%3D2
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+72871_91161.0924.0TransmembraneHelical%3B Name%3D1
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828105_123177.0920.0TransmembraneHelical%3B Name%3D2
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+82871_91177.0920.0TransmembraneHelical%3B Name%3D1
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828105_123177.0920.0TransmembraneHelical%3B Name%3D2
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+82871_91177.0920.0TransmembraneHelical%3B Name%3D1
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728105_123161.0924.0TransmembraneHelical%3B Name%3D2
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+72871_91161.0924.0TransmembraneHelical%3B Name%3D1
TgeneTMEM241chr3:130660543chr18:20889708ENST000003832331215271_291255.0297.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST0000039970706121_1410124.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST0000039970706146_1660124.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST0000039970706187_2070124.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST0000039970706211_2310124.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST0000039970706250_2700124.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST0000039970706271_2910124.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST000003997070632_520124.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST000003997070667_870124.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST00000399707067_290124.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST000003997070693_1130124.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727124_262177.0889.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727283_294177.0889.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727313_699177.0889.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727720_729177.0889.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727751_770177.0889.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727794_808177.0889.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727829_841177.0889.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727861_875177.0889.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727897_919177.0889.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728124_262177.0950.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728283_294177.0950.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728313_699177.0950.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728720_729177.0950.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728751_770177.0950.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728794_808177.0950.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728829_841177.0950.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728861_875177.0950.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728897_919177.0950.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728124_262211.0974.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728283_294211.0974.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728313_699211.0974.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728720_729211.0974.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728751_770211.0974.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728794_808211.0974.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728829_841211.0974.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728861_875211.0974.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728897_919211.0974.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728124_262177.0940.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728283_294177.0940.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728313_699177.0940.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728720_729177.0940.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728751_770177.0940.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728794_808177.0940.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728829_841177.0940.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728861_875177.0940.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728897_919177.0940.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727124_262177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727283_294177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727313_699177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727720_729177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727751_770177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727794_808177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727829_841177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727861_875177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727897_919177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727124_262161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727283_294161.0904.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727313_699161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727720_729161.0904.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727751_770161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727794_808161.0904.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727829_841161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727861_875161.0904.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727897_919161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727124_262161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727283_294161.0904.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727313_699161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727720_729161.0904.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727751_770161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727794_808161.0904.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727829_841161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727861_875161.0904.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727897_919161.0904.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728124_262161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728283_294161.0924.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728313_699161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728720_729161.0924.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728751_770161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728794_808161.0924.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728829_841161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728861_875161.0924.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728897_919161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828124_262177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828283_294177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828313_699177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828720_729177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828751_770177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828794_808177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828829_841177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828861_875177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828897_919177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828124_262177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828283_294177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828313_699177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828720_729177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828751_770177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828794_808177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828829_841177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828861_875177.0920.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828897_919177.0920.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728124_262161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728283_294161.0924.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728313_699161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728720_729161.0924.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728751_770161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728794_808161.0924.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728829_841161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728861_875161.0924.0Topological domainLumenal
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728897_919161.0924.0Topological domainCytoplasmic
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727263_282177.0889.0TransmembraneHelical%3B Name%3D3
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727295_312177.0889.0TransmembraneHelical%3B Name%3D4
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727700_719177.0889.0TransmembraneHelical%3B Name%3D5
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727730_750177.0889.0TransmembraneHelical%3B Name%3D6
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727771_793177.0889.0TransmembraneHelical%3B Name%3D7
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727809_828177.0889.0TransmembraneHelical%3B Name%3D8
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727842_860177.0889.0TransmembraneHelical%3B Name%3D9
HgeneATP2C1chr3:130660543chr18:20889708ENST00000328560+727876_896177.0889.0TransmembraneHelical%3B Name%3D10
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728263_282177.0950.0TransmembraneHelical%3B Name%3D3
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728295_312177.0950.0TransmembraneHelical%3B Name%3D4
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728700_719177.0950.0TransmembraneHelical%3B Name%3D5
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728730_750177.0950.0TransmembraneHelical%3B Name%3D6
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728771_793177.0950.0TransmembraneHelical%3B Name%3D7
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728809_828177.0950.0TransmembraneHelical%3B Name%3D8
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728842_860177.0950.0TransmembraneHelical%3B Name%3D9
HgeneATP2C1chr3:130660543chr18:20889708ENST00000359644+728876_896177.0950.0TransmembraneHelical%3B Name%3D10
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728263_282211.0974.0TransmembraneHelical%3B Name%3D3
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728295_312211.0974.0TransmembraneHelical%3B Name%3D4
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728700_719211.0974.0TransmembraneHelical%3B Name%3D5
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728730_750211.0974.0TransmembraneHelical%3B Name%3D6
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728771_793211.0974.0TransmembraneHelical%3B Name%3D7
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728809_828211.0974.0TransmembraneHelical%3B Name%3D8
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728842_860211.0974.0TransmembraneHelical%3B Name%3D9
HgeneATP2C1chr3:130660543chr18:20889708ENST00000393221+728876_896211.0974.0TransmembraneHelical%3B Name%3D10
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728263_282177.0940.0TransmembraneHelical%3B Name%3D3
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728295_312177.0940.0TransmembraneHelical%3B Name%3D4
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728700_719177.0940.0TransmembraneHelical%3B Name%3D5
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728730_750177.0940.0TransmembraneHelical%3B Name%3D6
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728771_793177.0940.0TransmembraneHelical%3B Name%3D7
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728809_828177.0940.0TransmembraneHelical%3B Name%3D8
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728842_860177.0940.0TransmembraneHelical%3B Name%3D9
HgeneATP2C1chr3:130660543chr18:20889708ENST00000422190+728876_896177.0940.0TransmembraneHelical%3B Name%3D10
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727263_282177.0920.0TransmembraneHelical%3B Name%3D3
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727295_312177.0920.0TransmembraneHelical%3B Name%3D4
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727700_719177.0920.0TransmembraneHelical%3B Name%3D5
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727730_750177.0920.0TransmembraneHelical%3B Name%3D6
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727771_793177.0920.0TransmembraneHelical%3B Name%3D7
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727809_828177.0920.0TransmembraneHelical%3B Name%3D8
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727842_860177.0920.0TransmembraneHelical%3B Name%3D9
HgeneATP2C1chr3:130660543chr18:20889708ENST00000428331+727876_896177.0920.0TransmembraneHelical%3B Name%3D10
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727263_282161.0904.0TransmembraneHelical%3B Name%3D3
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727295_312161.0904.0TransmembraneHelical%3B Name%3D4
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727700_719161.0904.0TransmembraneHelical%3B Name%3D5
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727730_750161.0904.0TransmembraneHelical%3B Name%3D6
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727771_793161.0904.0TransmembraneHelical%3B Name%3D7
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727809_828161.0904.0TransmembraneHelical%3B Name%3D8
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727842_860161.0904.0TransmembraneHelical%3B Name%3D9
HgeneATP2C1chr3:130660543chr18:20889708ENST00000504948+727876_896161.0904.0TransmembraneHelical%3B Name%3D10
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727263_282161.0904.0TransmembraneHelical%3B Name%3D3
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727295_312161.0904.0TransmembraneHelical%3B Name%3D4
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727700_719161.0904.0TransmembraneHelical%3B Name%3D5
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727730_750161.0904.0TransmembraneHelical%3B Name%3D6
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727771_793161.0904.0TransmembraneHelical%3B Name%3D7
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727809_828161.0904.0TransmembraneHelical%3B Name%3D8
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727842_860161.0904.0TransmembraneHelical%3B Name%3D9
HgeneATP2C1chr3:130660543chr18:20889708ENST00000505330+727876_896161.0904.0TransmembraneHelical%3B Name%3D10
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728263_282161.0924.0TransmembraneHelical%3B Name%3D3
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728295_312161.0924.0TransmembraneHelical%3B Name%3D4
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728700_719161.0924.0TransmembraneHelical%3B Name%3D5
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728730_750161.0924.0TransmembraneHelical%3B Name%3D6
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728771_793161.0924.0TransmembraneHelical%3B Name%3D7
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728809_828161.0924.0TransmembraneHelical%3B Name%3D8
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728842_860161.0924.0TransmembraneHelical%3B Name%3D9
HgeneATP2C1chr3:130660543chr18:20889708ENST00000507488+728876_896161.0924.0TransmembraneHelical%3B Name%3D10
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828263_282177.0920.0TransmembraneHelical%3B Name%3D3
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828295_312177.0920.0TransmembraneHelical%3B Name%3D4
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828700_719177.0920.0TransmembraneHelical%3B Name%3D5
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828730_750177.0920.0TransmembraneHelical%3B Name%3D6
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828771_793177.0920.0TransmembraneHelical%3B Name%3D7
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828809_828177.0920.0TransmembraneHelical%3B Name%3D8
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828842_860177.0920.0TransmembraneHelical%3B Name%3D9
HgeneATP2C1chr3:130660543chr18:20889708ENST00000508532+828876_896177.0920.0TransmembraneHelical%3B Name%3D10
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828263_282177.0920.0TransmembraneHelical%3B Name%3D3
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828295_312177.0920.0TransmembraneHelical%3B Name%3D4
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828700_719177.0920.0TransmembraneHelical%3B Name%3D5
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828730_750177.0920.0TransmembraneHelical%3B Name%3D6
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828771_793177.0920.0TransmembraneHelical%3B Name%3D7
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828809_828177.0920.0TransmembraneHelical%3B Name%3D8
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828842_860177.0920.0TransmembraneHelical%3B Name%3D9
HgeneATP2C1chr3:130660543chr18:20889708ENST00000510168+828876_896177.0920.0TransmembraneHelical%3B Name%3D10
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728263_282161.0924.0TransmembraneHelical%3B Name%3D3
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728295_312161.0924.0TransmembraneHelical%3B Name%3D4
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728700_719161.0924.0TransmembraneHelical%3B Name%3D5
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728730_750161.0924.0TransmembraneHelical%3B Name%3D6
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728771_793161.0924.0TransmembraneHelical%3B Name%3D7
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728809_828161.0924.0TransmembraneHelical%3B Name%3D8
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728842_860161.0924.0TransmembraneHelical%3B Name%3D9
HgeneATP2C1chr3:130660543chr18:20889708ENST00000513801+728876_896161.0924.0TransmembraneHelical%3B Name%3D10
TgeneTMEM241chr3:130660543chr18:20889708ENST000003832331215121_141255.0297.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST000003832331215146_166255.0297.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST000003832331215187_207255.0297.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST000003832331215211_231255.0297.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST000003832331215250_270255.0297.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST00000383233121532_52255.0297.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST00000383233121567_87255.0297.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST0000038323312157_29255.0297.0TransmembraneHelical
TgeneTMEM241chr3:130660543chr18:20889708ENST00000383233121593_113255.0297.0TransmembraneHelical


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
ATP2C1
TMEM241


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to ATP2C1-TMEM241


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to ATP2C1-TMEM241


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource