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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:ATP6V1C1-PML

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: ATP6V1C1-PML
	FusionPDB ID: 8158
	FusionGDB2.0 ID: 8158
		Hgene	Tgene
	Gene symbol	ATP6V1C1	PML
	Gene ID	528	5371
	Gene name	ATPase H+ transporting V1 subunit C1	promyelocytic leukemia
	Synonyms	ATP6C\|ATP6D\|VATC\|Vma5	MYL\|PP8675\|RNF71\|TRIM19
	Cytomap	8q22.3	15q24.1
	Type of gene	protein-coding	protein-coding
	Description	V-type proton ATPase subunit C 1ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1H(+)-transporting two-sector ATPase, subunit CH+ -ATPase C subunitH+-transporting ATPase chain C, vacuolarV-ATPase C subunitV-ATPase subunit C 1subunit C of vacu	protein PMLPML/RARA fusionRING finger protein 71probable transcription factor PMLpromyelocytic leukemia proteinpromyelocytic leukemia, inducer oftripartite motif protein TRIM19tripartite motif-containing protein 19
	Modification date	20200313	20200313
	UniProtAcc	P21283	PRAM1
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000395862, ENST00000518738, ENST00000521514, ENST00000518857,	ENST00000569161, ENST00000268058, ENST00000268059, ENST00000354026, ENST00000359928, ENST00000395132, ENST00000395135, ENST00000435786, ENST00000436891, ENST00000563500, ENST00000564428, ENST00000565898, ENST00000567543, ENST00000569477, ENST00000569965,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	9 X 7 X 6=378	9 X 24 X 6=1296
	# samples	11	28
	** MAII score	log2(11/378*10)=-1.78088271069641 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(28/1296*10)=-2.21056698593966 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: ATP6V1C1 [Title/Abstract] AND PML [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	ATP6V1C1(104054635)-PML(74315168), # samples:1 ATP6V1C1(104054635)-PML(74315169), # samples:1
Anticipated loss of major functional domain due to fusion event.	ATP6V1C1-PML seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ATP6V1C1-PML seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ATP6V1C1-PML seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ATP6V1C1-PML seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	PML	GO:0001666	response to hypoxia	16915281
Tgene	PML	GO:0030308	negative regulation of cell growth	9448006
Tgene	PML	GO:0034097	response to cytokine	9412458
Tgene	PML	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	22406621
Tgene	PML	GO:0045087	innate immune response	18248090
Tgene	PML	GO:0045892	negative regulation of transcription, DNA-templated	9448006
Tgene	PML	GO:0051457	maintenance of protein location in nucleus	17332504
Tgene	PML	GO:0065003	protein-containing complex assembly	12915590
Tgene	PML	GO:0090398	cellular senescence	22002537\|22117195\|23431171
Tgene	PML	GO:1902187	negative regulation of viral release from host cell	18248090

Fusion gene breakpoints across ATP6V1C1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PML (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	UCEC	TCGA-FI-A2F9-01A	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+
ChimerDB4	UCEC	TCGA-FI-A2F9	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000395135	PML	chr15	74315168	+	1816	359	135	1658	507
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000395132	PML	chr15	74315168	+	1399	359	1292	321	323
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000268059	PML	chr15	74315168	+	2690	359	135	2246	703
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000354026	PML	chr15	74315168	+	2546	359	135	2102	655
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000268058	PML	chr15	74315168	+	4169	359	135	2405	756
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000565898	PML	chr15	74315168	+	5066	359	135	2261	708
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000569477	PML	chr15	74315168	+	1926	359	135	1682	515
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000569965	PML	chr15	74315168	+	1825	359	135	1439	434
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000567543	PML	chr15	74315168	+	1092	359	135	1028	297
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000435786	PML	chr15	74315168	+	3331	359	135	1592	485
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000436891	PML	chr15	74315168	+	2698	359	135	1439	434
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000564428	PML	chr15	74315168	+	1673	359	135	1514	459
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000359928	PML	chr15	74315168	+	1414	359	135	1028	297
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000563500	PML	chr15	74315168	+	4249	359	135	1463	442
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000395135	PML	chr15	74315168	+	1820	363	139	1662	507
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000395132	PML	chr15	74315168	+	1403	363	1296	325	323
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000268059	PML	chr15	74315168	+	2694	363	139	2250	703
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000354026	PML	chr15	74315168	+	2550	363	139	2106	655
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000268058	PML	chr15	74315168	+	4173	363	139	2409	756
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000565898	PML	chr15	74315168	+	5070	363	139	2265	708
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000569477	PML	chr15	74315168	+	1930	363	139	1686	515
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000569965	PML	chr15	74315168	+	1829	363	139	1443	434
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000567543	PML	chr15	74315168	+	1096	363	139	1032	297
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000435786	PML	chr15	74315168	+	3335	363	139	1596	485
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000436891	PML	chr15	74315168	+	2702	363	139	1443	434
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000564428	PML	chr15	74315168	+	1677	363	139	1518	459
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000359928	PML	chr15	74315168	+	1418	363	139	1032	297
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000563500	PML	chr15	74315168	+	4253	363	139	1467	442
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000395135	PML	chr15	74315169	+	1816	359	135	1658	507
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000395132	PML	chr15	74315169	+	1399	359	1292	321	323
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000268059	PML	chr15	74315169	+	2690	359	135	2246	703
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000354026	PML	chr15	74315169	+	2546	359	135	2102	655
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000268058	PML	chr15	74315169	+	4169	359	135	2405	756
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000565898	PML	chr15	74315169	+	5066	359	135	2261	708
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000569477	PML	chr15	74315169	+	1926	359	135	1682	515
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000569965	PML	chr15	74315169	+	1825	359	135	1439	434
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000567543	PML	chr15	74315169	+	1092	359	135	1028	297
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000435786	PML	chr15	74315169	+	3331	359	135	1592	485
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000436891	PML	chr15	74315169	+	2698	359	135	1439	434
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000564428	PML	chr15	74315169	+	1673	359	135	1514	459
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000359928	PML	chr15	74315169	+	1414	359	135	1028	297
ENST00000395862	ATP6V1C1	chr8	104054635	+	ENST00000563500	PML	chr15	74315169	+	4249	359	135	1463	442
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000395135	PML	chr15	74315169	+	1820	363	139	1662	507
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000395132	PML	chr15	74315169	+	1403	363	1296	325	323
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000268059	PML	chr15	74315169	+	2694	363	139	2250	703
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000354026	PML	chr15	74315169	+	2550	363	139	2106	655
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000268058	PML	chr15	74315169	+	4173	363	139	2409	756
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000565898	PML	chr15	74315169	+	5070	363	139	2265	708
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000569477	PML	chr15	74315169	+	1930	363	139	1686	515
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000569965	PML	chr15	74315169	+	1829	363	139	1443	434
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000567543	PML	chr15	74315169	+	1096	363	139	1032	297
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000435786	PML	chr15	74315169	+	3335	363	139	1596	485
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000436891	PML	chr15	74315169	+	2702	363	139	1443	434
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000564428	PML	chr15	74315169	+	1677	363	139	1518	459
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000359928	PML	chr15	74315169	+	1418	363	139	1032	297
ENST00000518738	ATP6V1C1	chr8	104054635	+	ENST00000563500	PML	chr15	74315169	+	4253	363	139	1467	442

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000395862	ENST00000395135	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.019116236	0.9808837
ENST00000395862	ENST00000395132	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.012692175	0.98730785
ENST00000395862	ENST00000268059	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.050531566	0.9494685
ENST00000395862	ENST00000354026	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.07402372	0.9259763
ENST00000395862	ENST00000268058	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.008917114	0.9910829
ENST00000395862	ENST00000565898	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.006238618	0.99376136
ENST00000395862	ENST00000569477	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.026103262	0.97389674
ENST00000395862	ENST00000569965	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.018483967	0.981516
ENST00000395862	ENST00000567543	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.00852995	0.99147004
ENST00000395862	ENST00000435786	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.015279641	0.98472035
ENST00000395862	ENST00000436891	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.017740827	0.98225915
ENST00000395862	ENST00000564428	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.017740402	0.98225963
ENST00000395862	ENST00000359928	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.011055579	0.9889444
ENST00000395862	ENST00000563500	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.016479457	0.98352057
ENST00000518738	ENST00000395135	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.01810373	0.9818963
ENST00000518738	ENST00000395132	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.011809649	0.9881904
ENST00000518738	ENST00000268059	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.04898015	0.9510198
ENST00000518738	ENST00000354026	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.072623305	0.9273767
ENST00000518738	ENST00000268058	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.008736209	0.99126387
ENST00000518738	ENST00000565898	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.006109783	0.99389017
ENST00000518738	ENST00000569477	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.025029687	0.97497034
ENST00000518738	ENST00000569965	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.017596425	0.98240364
ENST00000518738	ENST00000567543	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.008260774	0.99173915
ENST00000518738	ENST00000435786	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.014862971	0.985137
ENST00000518738	ENST00000436891	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.016962918	0.98303705
ENST00000518738	ENST00000564428	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.017259106	0.9827408
ENST00000518738	ENST00000359928	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.010460919	0.9895391
ENST00000518738	ENST00000563500	ATP6V1C1	chr8	104054635	+	PML	chr15	74315168	+	0.015917068	0.9840829
ENST00000395862	ENST00000395135	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.019116236	0.9808837
ENST00000395862	ENST00000395132	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.012692175	0.98730785
ENST00000395862	ENST00000268059	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.050531566	0.9494685
ENST00000395862	ENST00000354026	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.07402372	0.9259763
ENST00000395862	ENST00000268058	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.008917114	0.9910829
ENST00000395862	ENST00000565898	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.006238618	0.99376136
ENST00000395862	ENST00000569477	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.026103262	0.97389674
ENST00000395862	ENST00000569965	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.018483967	0.981516
ENST00000395862	ENST00000567543	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.00852995	0.99147004
ENST00000395862	ENST00000435786	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.015279641	0.98472035
ENST00000395862	ENST00000436891	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.017740827	0.98225915
ENST00000395862	ENST00000564428	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.017740402	0.98225963
ENST00000395862	ENST00000359928	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.011055579	0.9889444
ENST00000395862	ENST00000563500	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.016479457	0.98352057
ENST00000518738	ENST00000395135	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.01810373	0.9818963
ENST00000518738	ENST00000395132	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.011809649	0.9881904
ENST00000518738	ENST00000268059	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.04898015	0.9510198
ENST00000518738	ENST00000354026	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.072623305	0.9273767
ENST00000518738	ENST00000268058	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.008736209	0.99126387
ENST00000518738	ENST00000565898	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.006109783	0.99389017
ENST00000518738	ENST00000569477	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.025029687	0.97497034
ENST00000518738	ENST00000569965	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.017596425	0.98240364
ENST00000518738	ENST00000567543	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.008260774	0.99173915
ENST00000518738	ENST00000435786	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.014862971	0.985137
ENST00000518738	ENST00000436891	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.016962918	0.98303705
ENST00000518738	ENST00000564428	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.017259106	0.9827408
ENST00000518738	ENST00000359928	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.010460919	0.9895391
ENST00000518738	ENST00000563500	ATP6V1C1	chr8	104054635	+	PML	chr15	74315169	+	0.015917068	0.9840829

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>8158_8158_1_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000268058_length(amino acids)=756AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELD
DSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFL
SSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFLAALPLIRERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRL
LEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVSFMELLSAHRRDRQGGLKKYSRYLSLQTTTLPPAQPAFNLQAL

--------------------------------------------------------------

>8158_8158_2_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000268059_length(amino acids)=703AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPME
TAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAI
RLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQLQRGISPPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSS

--------------------------------------------------------------

>8158_8158_3_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000354026_length(amino acids)=655AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPP
HQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQ
LQRGISPPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVGAGESRAQTLGAGVPPGDSVRGSMEASQVQVPLEASP

--------------------------------------------------------------

>8158_8158_4_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000359928_length(amino acids)=297AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA

--------------------------------------------------------------

>8158_8158_5_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000395132_length(amino acids)=323AA_BP=1
MGWGSGHGRLCYWPGTQNTGECKGDRSFFLGQRGLEWWLESQPCLSLPLSAREDPGLPAQRSMHSHSFVDSFLNQELMSATLCRACKSMG
WRRQQVNVNRVPGSAGSLWAGFLGYSCIFPLGDARAEVLQAHLELVEAIGAHGSLQALGLLLAQAAERLAQETVHVQHLLVRGVALHPLH
QRAARADALQHSIQAAQPTGHLLVVALVPRVHSLQQLALLSPHVSYHLAHALADQLLGLGTRAAQLADGRVHLRVNRAKGTILLLQRLRH

--------------------------------------------------------------

>8158_8158_6_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000395135_length(amino acids)=507AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELD

--------------------------------------------------------------

>8158_8158_7_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000435786_length(amino acids)=485AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSVSGPEV

--------------------------------------------------------------

>8158_8158_8_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000436891_length(amino acids)=434AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR

--------------------------------------------------------------

>8158_8158_9_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000563500_length(amino acids)=442AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG

--------------------------------------------------------------

>8158_8158_10_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000564428_length(amino acids)=459AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNESGFS

--------------------------------------------------------------

>8158_8158_11_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000565898_length(amino acids)=708AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKI
SQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFLSSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFLAALPLI
RERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRLLEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVS

--------------------------------------------------------------

>8158_8158_12_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000567543_length(amino acids)=297AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA

--------------------------------------------------------------

>8158_8158_13_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000569477_length(amino acids)=515AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSVSSSPQ

--------------------------------------------------------------

>8158_8158_14_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315168_ENST00000569965_length(amino acids)=434AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR

--------------------------------------------------------------

>8158_8158_15_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000268058_length(amino acids)=756AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELD
DSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFL
SSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFLAALPLIRERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRL
LEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVSFMELLSAHRRDRQGGLKKYSRYLSLQTTTLPPAQPAFNLQAL

--------------------------------------------------------------

>8158_8158_16_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000268059_length(amino acids)=703AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPME
TAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAI
RLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQLQRGISPPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSS

--------------------------------------------------------------

>8158_8158_17_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000354026_length(amino acids)=655AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPP
HQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQ
LQRGISPPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVGAGESRAQTLGAGVPPGDSVRGSMEASQVQVPLEASP

--------------------------------------------------------------

>8158_8158_18_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000359928_length(amino acids)=297AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA

--------------------------------------------------------------

>8158_8158_19_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000395132_length(amino acids)=323AA_BP=1
MGWGSGHGRLCYWPGTQNTGECKGDRSFFLGQRGLEWWLESQPCLSLPLSAREDPGLPAQRSMHSHSFVDSFLNQELMSATLCRACKSMG
WRRQQVNVNRVPGSAGSLWAGFLGYSCIFPLGDARAEVLQAHLELVEAIGAHGSLQALGLLLAQAAERLAQETVHVQHLLVRGVALHPLH
QRAARADALQHSIQAAQPTGHLLVVALVPRVHSLQQLALLSPHVSYHLAHALADQLLGLGTRAAQLADGRVHLRVNRAKGTILLLQRLRH

--------------------------------------------------------------

>8158_8158_20_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000395135_length(amino acids)=507AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELD

--------------------------------------------------------------

>8158_8158_21_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000435786_length(amino acids)=485AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSVSGPEV

--------------------------------------------------------------

>8158_8158_22_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000436891_length(amino acids)=434AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR

--------------------------------------------------------------

>8158_8158_23_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000563500_length(amino acids)=442AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG

--------------------------------------------------------------

>8158_8158_24_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000564428_length(amino acids)=459AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNESGFS

--------------------------------------------------------------

>8158_8158_25_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000565898_length(amino acids)=708AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKI
SQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFLSSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFLAALPLI
RERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRLLEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVS

--------------------------------------------------------------

>8158_8158_26_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000567543_length(amino acids)=297AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA

--------------------------------------------------------------

>8158_8158_27_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000569477_length(amino acids)=515AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSVSSSPQ

--------------------------------------------------------------

>8158_8158_28_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000395862_PML_chr15_74315169_ENST00000569965_length(amino acids)=434AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR

--------------------------------------------------------------

>8158_8158_29_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000268058_length(amino acids)=756AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELD
DSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFL
SSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFLAALPLIRERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRL
LEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVSFMELLSAHRRDRQGGLKKYSRYLSLQTTTLPPAQPAFNLQAL

--------------------------------------------------------------

>8158_8158_30_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000268059_length(amino acids)=703AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPME
TAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAI
RLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQLQRGISPPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSS

--------------------------------------------------------------

>8158_8158_31_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000354026_length(amino acids)=655AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPP
HQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQ
LQRGISPPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVGAGESRAQTLGAGVPPGDSVRGSMEASQVQVPLEASP

--------------------------------------------------------------

>8158_8158_32_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000359928_length(amino acids)=297AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA

--------------------------------------------------------------

>8158_8158_33_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000395132_length(amino acids)=323AA_BP=1
MGWGSGHGRLCYWPGTQNTGECKGDRSFFLGQRGLEWWLESQPCLSLPLSAREDPGLPAQRSMHSHSFVDSFLNQELMSATLCRACKSMG
WRRQQVNVNRVPGSAGSLWAGFLGYSCIFPLGDARAEVLQAHLELVEAIGAHGSLQALGLLLAQAAERLAQETVHVQHLLVRGVALHPLH
QRAARADALQHSIQAAQPTGHLLVVALVPRVHSLQQLALLSPHVSYHLAHALADQLLGLGTRAAQLADGRVHLRVNRAKGTILLLQRLRH

--------------------------------------------------------------

>8158_8158_34_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000395135_length(amino acids)=507AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELD

--------------------------------------------------------------

>8158_8158_35_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000435786_length(amino acids)=485AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSVSGPEV

--------------------------------------------------------------

>8158_8158_36_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000436891_length(amino acids)=434AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR

--------------------------------------------------------------

>8158_8158_37_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000563500_length(amino acids)=442AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG

--------------------------------------------------------------

>8158_8158_38_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000564428_length(amino acids)=459AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNESGFS

--------------------------------------------------------------

>8158_8158_39_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000565898_length(amino acids)=708AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKI
SQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFLSSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFLAALPLI
RERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRLLEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVS

--------------------------------------------------------------

>8158_8158_40_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000567543_length(amino acids)=297AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA

--------------------------------------------------------------

>8158_8158_41_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000569477_length(amino acids)=515AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSVSSSPQ

--------------------------------------------------------------

>8158_8158_42_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315168_ENST00000569965_length(amino acids)=434AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR

--------------------------------------------------------------

>8158_8158_43_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000268058_length(amino acids)=756AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELD
DSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFL
SSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFLAALPLIRERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRL
LEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVSFMELLSAHRRDRQGGLKKYSRYLSLQTTTLPPAQPAFNLQAL

--------------------------------------------------------------

>8158_8158_44_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000268059_length(amino acids)=703AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPME
TAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAI
RLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQLQRGISPPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSS

--------------------------------------------------------------

>8158_8158_45_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000354026_length(amino acids)=655AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPP
HQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQ
LQRGISPPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVGAGESRAQTLGAGVPPGDSVRGSMEASQVQVPLEASP

--------------------------------------------------------------

>8158_8158_46_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000359928_length(amino acids)=297AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA

--------------------------------------------------------------

>8158_8158_47_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000395132_length(amino acids)=323AA_BP=1
MGWGSGHGRLCYWPGTQNTGECKGDRSFFLGQRGLEWWLESQPCLSLPLSAREDPGLPAQRSMHSHSFVDSFLNQELMSATLCRACKSMG
WRRQQVNVNRVPGSAGSLWAGFLGYSCIFPLGDARAEVLQAHLELVEAIGAHGSLQALGLLLAQAAERLAQETVHVQHLLVRGVALHPLH
QRAARADALQHSIQAAQPTGHLLVVALVPRVHSLQQLALLSPHVSYHLAHALADQLLGLGTRAAQLADGRVHLRVNRAKGTILLLQRLRH

--------------------------------------------------------------

>8158_8158_48_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000395135_length(amino acids)=507AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELD

--------------------------------------------------------------

>8158_8158_49_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000435786_length(amino acids)=485AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSVSGPEV

--------------------------------------------------------------

>8158_8158_50_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000436891_length(amino acids)=434AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR

--------------------------------------------------------------

>8158_8158_51_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000563500_length(amino acids)=442AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG

--------------------------------------------------------------

>8158_8158_52_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000564428_length(amino acids)=459AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNESGFS

--------------------------------------------------------------

>8158_8158_53_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000565898_length(amino acids)=708AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIG
SEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKI
SQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFLSSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFLAALPLI
RERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRLLEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVS

--------------------------------------------------------------

>8158_8158_54_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000567543_length(amino acids)=297AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA

--------------------------------------------------------------

>8158_8158_55_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000569477_length(amino acids)=515AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR
KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSVSSSPQ

--------------------------------------------------------------

>8158_8158_56_ATP6V1C1-PML_ATP6V1C1_chr8_104054635_ENST00000518738_PML_chr15_74315169_ENST00000569965_length(amino acids)=434AA_BP=75
MRKYLVTNMTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGIYCRGCSKPLCCSCA
LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ
RDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDA
AVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPR

--------------------------------------------------------------

Top

Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:104054635/chr15:74315168)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ATP6V1C1 P21283	PML PRAM1
FUNCTION: Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	670

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268058

228_253

200.66666666666666

883.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268059

228_253

200.66666666666666

830.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000354026

228_253

200.66666666666666

782.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000359928

228_253

200.66666666666666

474.6666666666667

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395132

228_253

200.66666666666666

436.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395135

228_253

200.66666666666666

634.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000435786

228_253

200.66666666666666

612.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000436891

228_253

200.66666666666666

902.6666666666666

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000564428

228_253

200.66666666666666

586.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000565898

228_253

200.66666666666666

835.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000567543

228_253

200.66666666666666

424.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569477

228_253

200.66666666666666

642.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569965

228_253

200.66666666666666

608.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268058

228_253

200.66666666666666

883.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268059

228_253

200.66666666666666

830.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000354026

228_253

200.66666666666666

782.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000359928

228_253

200.66666666666666

474.6666666666667

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395132

228_253

200.66666666666666

436.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395135

228_253

200.66666666666666

634.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000435786

228_253

200.66666666666666

612.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000436891

228_253

200.66666666666666

902.6666666666666

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000564428

228_253

200.66666666666666

586.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000565898

228_253

200.66666666666666

835.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000567543

228_253

200.66666666666666

424.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569477

228_253

200.66666666666666

642.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569965

228_253

200.66666666666666

608.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268058

476_490

200.66666666666666

883.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268059

476_490

200.66666666666666

830.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000354026

476_490

200.66666666666666

782.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000359928

476_490

200.66666666666666

474.6666666666667

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395132

476_490

200.66666666666666

436.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395135

476_490

200.66666666666666

634.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000435786

476_490

200.66666666666666

612.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000436891

476_490

200.66666666666666

902.6666666666666

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000564428

476_490

200.66666666666666

586.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000565898

476_490

200.66666666666666

835.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000567543

476_490

200.66666666666666

424.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569477

476_490

200.66666666666666

642.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569965

476_490

200.66666666666666

608.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268058

476_490

200.66666666666666

883.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268059

476_490

200.66666666666666

830.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000354026

476_490

200.66666666666666

782.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000359928

476_490

200.66666666666666

474.6666666666667

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395132

476_490

200.66666666666666

436.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395135

476_490

200.66666666666666

634.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000435786

476_490

200.66666666666666

612.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000436891

476_490

200.66666666666666

902.6666666666666

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000564428

476_490

200.66666666666666

586.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000565898

476_490

200.66666666666666

835.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000567543

476_490

200.66666666666666

424.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569477

476_490

200.66666666666666

642.0

Motif

Note=Nuclear localization signal

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569965

476_490

200.66666666666666

608.0

Motif

Note=Nuclear localization signal

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268058

3_46

200.66666666666666

883.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268059

3_46

200.66666666666666

830.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000354026

3_46

200.66666666666666

782.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000359928

3_46

200.66666666666666

474.6666666666667

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395132

3_46

200.66666666666666

436.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395135

3_46

200.66666666666666

634.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000435786

3_46

200.66666666666666

612.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000436891

3_46

200.66666666666666

902.6666666666666

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000564428

3_46

200.66666666666666

586.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000565898

3_46

200.66666666666666

835.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000567543

3_46

200.66666666666666

424.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569477

3_46

200.66666666666666

642.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569965

3_46

200.66666666666666

608.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268058

3_46

200.66666666666666

883.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268059

3_46

200.66666666666666

830.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000354026

3_46

200.66666666666666

782.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000359928

3_46

200.66666666666666

474.6666666666667

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395132

3_46

200.66666666666666

436.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395135

3_46

200.66666666666666

634.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000435786

3_46

200.66666666666666

612.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000436891

3_46

200.66666666666666

902.6666666666666

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000564428

3_46

200.66666666666666

586.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000565898

3_46

200.66666666666666

835.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000567543

3_46

200.66666666666666

424.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569477

3_46

200.66666666666666

642.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569965

3_46

200.66666666666666

608.0

Compositional bias

Note=Pro-rich

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268058

124_166

200.66666666666666

883.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268058

183_236

200.66666666666666

883.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268058

57_92

200.66666666666666

883.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268059

124_166

200.66666666666666

830.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268059

183_236

200.66666666666666

830.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000268059

57_92

200.66666666666666

830.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000354026

124_166

200.66666666666666

782.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000354026

183_236

200.66666666666666

782.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000354026

57_92

200.66666666666666

782.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000359928

124_166

200.66666666666666

474.6666666666667

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000359928

183_236

200.66666666666666

474.6666666666667

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000359928

57_92

200.66666666666666

474.6666666666667

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395132

124_166

200.66666666666666

436.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395132

183_236

200.66666666666666

436.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395132

57_92

200.66666666666666

436.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395135

124_166

200.66666666666666

634.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395135

183_236

200.66666666666666

634.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000395135

57_92

200.66666666666666

634.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000435786

124_166

200.66666666666666

612.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000435786

183_236

200.66666666666666

612.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000435786

57_92

200.66666666666666

612.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000436891

124_166

200.66666666666666

902.6666666666666

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000436891

183_236

200.66666666666666

902.6666666666666

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000436891

57_92

200.66666666666666

902.6666666666666

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000564428

124_166

200.66666666666666

586.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000564428

183_236

200.66666666666666

586.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000564428

57_92

200.66666666666666

586.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000565898

124_166

200.66666666666666

835.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000565898

183_236

200.66666666666666

835.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000565898

57_92

200.66666666666666

835.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000567543

124_166

200.66666666666666

424.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000567543

183_236

200.66666666666666

424.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000567543

57_92

200.66666666666666

424.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569477

124_166

200.66666666666666

642.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569477

183_236

200.66666666666666

642.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569477

57_92

200.66666666666666

642.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569965

124_166

200.66666666666666

608.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569965

183_236

200.66666666666666

608.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315168

ENST00000569965

57_92

200.66666666666666

608.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268058

124_166

200.66666666666666

883.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268058

183_236

200.66666666666666

883.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268058

57_92

200.66666666666666

883.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268059

124_166

200.66666666666666

830.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268059

183_236

200.66666666666666

830.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000268059

57_92

200.66666666666666

830.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000354026

124_166

200.66666666666666

782.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000354026

183_236

200.66666666666666

782.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000354026

57_92

200.66666666666666

782.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000359928

124_166

200.66666666666666

474.6666666666667

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000359928

183_236

200.66666666666666

474.6666666666667

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000359928

57_92

200.66666666666666

474.6666666666667

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395132

124_166

200.66666666666666

436.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395132

183_236

200.66666666666666

436.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395132

57_92

200.66666666666666

436.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395135

124_166

200.66666666666666

634.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395135

183_236

200.66666666666666

634.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000395135

57_92

200.66666666666666

634.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000435786

124_166

200.66666666666666

612.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000435786

183_236

200.66666666666666

612.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000435786

57_92

200.66666666666666

612.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000436891

124_166

200.66666666666666

902.6666666666666

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000436891

183_236

200.66666666666666

902.6666666666666

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000436891

57_92

200.66666666666666

902.6666666666666

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000564428

124_166

200.66666666666666

586.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000564428

183_236

200.66666666666666

586.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000564428

57_92

200.66666666666666

586.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000565898

124_166

200.66666666666666

835.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000565898

183_236

200.66666666666666

835.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000565898

57_92

200.66666666666666

835.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000567543

124_166

200.66666666666666

424.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000567543

183_236

200.66666666666666

424.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000567543

57_92

200.66666666666666

424.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569477

124_166

200.66666666666666

642.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569477

183_236

200.66666666666666

642.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569477

57_92

200.66666666666666

642.0

Zinc finger

RING-type

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569965

124_166

200.66666666666666

608.0

Zinc finger

B box-type 1%3B atypical

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569965

183_236

200.66666666666666

608.0

Zinc finger

B box-type 2

Tgene

PML

chr8:104054635

chr15:74315169

ENST00000569965

57_92

200.66666666666666

608.0

Zinc finger

RING-type

Top

Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

PML

GATA2, TDG, CHFR, DAXX, SMAD3, SMAD2, ZFYVE9, MAPK11, MDM2, RPL11, MYB, ANKRD2, TP53, TRIM69, TOPBP1, CCNT1, SRF, CREBBP, SUMO1, NCOR2, SIN3A, NCOR1, HDAC1, SKI, HDAC3, HDAC2, PML, RARA, RXRA, TRIM24, RB1, EIF4E, RELA, HHEX, NR4A1, STAT3, JUN, FOS, ATF2, UBE2I, BCL6, ZBTB16, SP1, ARNT, TRIM27, PLAGL1, UBE2U, NR2C1, KAT5, SATB1, TERT, NR3C1, POLR2E, PPARG, MED7, PCBD2, CHD4, SAP25, ZNF506, FOXO1, HDAC7, TOP2B, SAP130, HNRNPU, RFC4, NPM1, MRTO4, SNRNP40, RUNX1, SIAH1, SF1, SMARCA4, KLHL20, SPI1, BANP, UBE3A, TGIF1, SP100, RS1, PIAS2, SUMO2, SUMO3, AXIN1, MAGEA2, RNF4, SETDB1, PSME3, H2AFX, ATXN3, PIAS1, CSNK2A1, MAF, TERF2IP, ARIH2, BKRF1, USP7, CSNK2B, RL2, YAP1, CTNNB1, RANBP2, RBCK1, MAP2K4, FBXO3, CUL1, SKP1, RBX1, PIN1, UHRF1, HIPK2, TOPORS, IKBKE, ZMYM2, SLC1A2, ORF23, WRN, IER3, RAD51, CHEK2, SYNE2, MAPK3, MAPK1, SIAH2, MYC, UL123, ARID3A, RUNX3, RUNX2, PKM, CSNK2A3, PLCG1, ELF4, BCL2, AURKA, SIRT1, TP63, NFATC1, FAS, MTOR, CSNK1D, EZH2, SUZ12, ECT2, MAPK7, CDK1, CDK2, CDK6, RNF111, LMNA, HDAC6, HDAC11, RNF125, KAT6A, PSMA3, CASP8AP2, ADH1B, NFKB1, PLSCR1, SH3GL1, smt3, GLIS2, JAK1, ATF7IP, ATXN1, HTT, EHMT2, ATRX, H3F3A, HIRA, ASF1A, NCOA2, EGFR, RPL5, RBL2, E2F4, TBX3, TBX2, PYCARD, SKIL, SENP1, Senp2, SNX11, RFPL4B, FHL3, ACOT8, Per2, PER2, NTRK1, TCF7L2, IFI16, PARK7, DNM2, KRAS, CASC5, FIP1L1, DSN1, SQSTM1, PLOD3, HOMER3, ATP5J2, TOMM20, HMGXB4, WDR5, INTS7, TCTN3, UQCRQ, TBC1D14, COLGALT1, SFXN3, DPH7, C1QTNF6, NANP, EME1, GOLGA6A, TIMM23, Rbm8a, Espl1, MAP1LC3B, GATA1, STAT1, STAT2, NACC1, PPARGC1A, NR1I3, CDKN2A, USP11, NF1, TUBA3C, GOPC, TULP3, KLHL40, NDUFS1, TRIML2, WDR45B, NDUFA2, RNF123, PADI3, ARHGEF16, CDH19, SPTA1, TRIM25, TRIM22, CIITA, CACUL1, PCBP1, TES, ZNF451, EGLN3, TRIB3, KPNA4, E6, EIF3K, ESR2, DCPS, TP53BP1, BRCA1, MDC1, SP3, TET2, BMP7, Hipk2, GBAS, DNAJC11, HADHB, VDAC2, VDAC3, APEX1, MAD1L1, PAK7, XRCC1, CBFB, PLEKHA4, FANCD2, E7, BUB3, nsp6, ERCC6, NEK4, KIF14, KIF20A, BRD1, BRD8, PHIP, TRIM66, AIM2, PYHIN1, E2F1, IL12RB1, NFKB2, HULC, NUPR1, BRD4, Apc2, CASP8, RIN3, DNAJB1, DDX58, LMNB1, MAP1LC3A, FXR1, NAA40, C3orf52, XIAP, TRIM52, BIRC2, CALM1, S100B, S100A2, CALML3, TNNC2, TMED7, USF1, PRMT8, SSUH2, ZNF784, TUBB3, HIST1H4A, KMT2A, NSMCE2, SMC5, SMC6, TERF2, APP, MORC3, FBXW7, PTPN11, E2F3, SIRT6, HNF4A,

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
ATP6V1C1
PML

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs to ATP6V1C1-PML

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

Top

Related Diseases to ATP6V1C1-PML

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Tgene	PML	C0023487	Acute Promyelocytic Leukemia	21	CTD_human;ORPHANET
Tgene	PML	C0014518	Toxic Epidermal Necrolysis	1	CTD_human
Tgene	PML	C0017636	Glioblastoma	1	CTD_human
Tgene	PML	C0019207	Hepatoma, Morris	1	CTD_human
Tgene	PML	C0019208	Hepatoma, Novikoff	1	CTD_human
Tgene	PML	C0023904	Liver Neoplasms, Experimental	1	CTD_human
Tgene	PML	C0027627	Neoplasm Metastasis	1	CTD_human
Tgene	PML	C0029401	Osteitis Deformans	1	CTD_human
Tgene	PML	C0033578	Prostatic Neoplasms	1	CTD_human
Tgene	PML	C0036341	Schizophrenia	1	CTD_human
Tgene	PML	C0038325	Stevens-Johnson Syndrome	1	CTD_human
Tgene	PML	C0085183	Neoplasms, Second Primary	1	CTD_human
Tgene	PML	C0086404	Experimental Hepatoma	1	CTD_human
Tgene	PML	C0086696	Neoplasms, Therapy-Associated	1	CTD_human
Tgene	PML	C0334588	Giant Cell Glioblastoma	1	CTD_human
Tgene	PML	C0376358	Malignant neoplasm of prostate	1	CTD_human
Tgene	PML	C0877578	Treatment related secondary malignancy	1	CTD_human
Tgene	PML	C1274933	Drug-Induced Stevens Johnson Syndrome	1	CTD_human
Tgene	PML	C1621958	Glioblastoma Multiforme	1	CTD_human
Tgene	PML	C3658301	Mycoplasma-Induced Stevens-Johnson Syndrome	1	CTD_human
Tgene	PML	C3658302	Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum	1	CTD_human