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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein Structure
	pLDDT scores
	Ramachandran Plot of Fusion Protein Structure
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:SMC5-IMMP2L

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: SMC5-IMMP2L
	FusionPDB ID: 84018
	FusionGDB2.0 ID: 84018
		Hgene	Tgene
	Gene symbol	SMC5	IMMP2L
	Gene ID	23137	83943
	Gene name	structural maintenance of chromosomes 5	inner mitochondrial membrane peptidase subunit 2
	Synonyms	SMC5L1	IMMP2L-IT1\|IMP2\|IMP2-LIKE
	Cytomap	9q21.12	7q31.1
	Type of gene	protein-coding	protein-coding
	Description	structural maintenance of chromosomes protein 5SMC protein 5SMC-5SMC5 structural maintenance of chromosomes 5-like 1hSMC5	mitochondrial inner membrane protease subunit 2IMP2 inner mitochondrial membrane peptidase-likeIMP2 inner mitochondrial membrane protease-likeinner mitochondrial membrane peptidase 2 like
	Modification date	20200313	20200313
	UniProtAcc	SLF2,FAM178A	Q96T52
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000361138, ENST00000471372,	ENST00000450877, ENST00000489381, ENST00000331762, ENST00000405709, ENST00000415362, ENST00000437687, ENST00000447215, ENST00000452895,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	8 X 10 X 4=320	29 X 19 X 14=7714
	# samples	9	32
	** MAII score	log2(9/320*10)=-1.83007499855769 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(32/7714*10)=-4.5913353357414 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: SMC5 [Title/Abstract] AND IMMP2L [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	SMC5(72882891)-IMMP2L(110603621), # samples:4
Anticipated loss of major functional domain due to fusion event.	SMC5-IMMP2L seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. SMC5-IMMP2L seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	SMC5	GO:0006974	cellular response to DNA damage stimulus	11408570\|25931565

Fusion gene breakpoints across SMC5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across IMMP2L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-AO-A124-01A	SMC5	chr9	72882890	+	IMMP2L	chr7	110603620	-
ChimerDB4	BRCA	TCGA-AO-A124-01A	SMC5	chr9	72882891	-	IMMP2L	chr7	110603621	-
ChimerDB4	BRCA	TCGA-AO-A124-01A	SMC5	chr9	72882891	+	IMMP2L	chr7	110603621	-
ChimerDB4	BRCA	TCGA-AO-A124	SMC5	chr9	72882891	+	IMMP2L	chr7	110603621	-

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000361138	SMC5	chr9	72882891	+	ENST00000405709	IMMP2L	chr7	110603621	-	1275	438	34	726	230
ENST00000361138	SMC5	chr9	72882891	+	ENST00000331762	IMMP2L	chr7	110603621	-	1275	438	34	726	230
ENST00000361138	SMC5	chr9	72882891	+	ENST00000452895	IMMP2L	chr7	110603621	-	913	438	34	726	230
ENST00000361138	SMC5	chr9	72882891	+	ENST00000415362	IMMP2L	chr7	110603621	-	727	438	34	726	231
ENST00000361138	SMC5	chr9	72882891	+	ENST00000447215	IMMP2L	chr7	110603621	-	1287	438	590	0	197
ENST00000361138	SMC5	chr9	72882891	+	ENST00000437687	IMMP2L	chr7	110603621	-	532	438	503	0	168
ENST00000361138	SMC5	chr9	72882890	+	ENST00000405709	IMMP2L	chr7	110603620	-	1275	438	34	726	230
ENST00000361138	SMC5	chr9	72882890	+	ENST00000331762	IMMP2L	chr7	110603620	-	1275	438	34	726	230
ENST00000361138	SMC5	chr9	72882890	+	ENST00000452895	IMMP2L	chr7	110603620	-	913	438	34	726	230
ENST00000361138	SMC5	chr9	72882890	+	ENST00000415362	IMMP2L	chr7	110603620	-	727	438	34	726	231
ENST00000361138	SMC5	chr9	72882890	+	ENST00000447215	IMMP2L	chr7	110603620	-	1287	438	590	0	197
ENST00000361138	SMC5	chr9	72882890	+	ENST00000437687	IMMP2L	chr7	110603620	-	532	438	503	0	168

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000361138	ENST00000405709	SMC5	chr9	72882891	+	IMMP2L	chr7	110603621	-	0.02961788	0.9703821
ENST00000361138	ENST00000331762	SMC5	chr9	72882891	+	IMMP2L	chr7	110603621	-	0.02961788	0.9703821
ENST00000361138	ENST00000452895	SMC5	chr9	72882891	+	IMMP2L	chr7	110603621	-	0.065970115	0.9340299
ENST00000361138	ENST00000415362	SMC5	chr9	72882891	+	IMMP2L	chr7	110603621	-	0.06380206	0.93619794
ENST00000361138	ENST00000447215	SMC5	chr9	72882891	+	IMMP2L	chr7	110603621	-	0.012187611	0.98781246
ENST00000361138	ENST00000437687	SMC5	chr9	72882891	+	IMMP2L	chr7	110603621	-	0.017188836	0.9828112
ENST00000361138	ENST00000405709	SMC5	chr9	72882890	+	IMMP2L	chr7	110603620	-	0.02961788	0.9703821
ENST00000361138	ENST00000331762	SMC5	chr9	72882890	+	IMMP2L	chr7	110603620	-	0.02961788	0.9703821
ENST00000361138	ENST00000452895	SMC5	chr9	72882890	+	IMMP2L	chr7	110603620	-	0.065970115	0.9340299
ENST00000361138	ENST00000415362	SMC5	chr9	72882890	+	IMMP2L	chr7	110603620	-	0.06380206	0.93619794
ENST00000361138	ENST00000447215	SMC5	chr9	72882890	+	IMMP2L	chr7	110603620	-	0.012187611	0.98781246
ENST00000361138	ENST00000437687	SMC5	chr9	72882890	+	IMMP2L	chr7	110603620	-	0.017188836	0.9828112

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>84018_84018_1_SMC5-IMMP2L_SMC5_chr9_72882890_ENST00000361138_IMMP2L_chr7_110603620_ENST00000331762_length(amino acids)=230AA_BP=135
MWDAEEARMATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMENFLTYDICEVSPGPHLNMIVGAN
GTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSRGMVEIELSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHH

--------------------------------------------------------------

>84018_84018_2_SMC5-IMMP2L_SMC5_chr9_72882890_ENST00000361138_IMMP2L_chr7_110603620_ENST00000405709_length(amino acids)=230AA_BP=135
MWDAEEARMATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMENFLTYDICEVSPGPHLNMIVGAN
GTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSRGMVEIELSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHH

--------------------------------------------------------------

>84018_84018_3_SMC5-IMMP2L_SMC5_chr9_72882890_ENST00000361138_IMMP2L_chr7_110603620_ENST00000415362_length(amino acids)=231AA_BP=135
MWDAEEARMATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMENFLTYDICEVSPGPHLNMIVGAN
GTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSRGMVEIELSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHH

--------------------------------------------------------------

>84018_84018_4_SMC5-IMMP2L_SMC5_chr9_72882890_ENST00000361138_IMMP2L_chr7_110603620_ENST00000437687_length(amino acids)=168AA_BP=1
MTISPSRAITLLMIFCSGFLGDNSISTMPLEHPLFTKNPTLSARPMKAGFPAKPRQMAHTMLDFPVPLAPTIIFKWGPGDTSQISYVRKF

--------------------------------------------------------------

>84018_84018_5_SMC5-IMMP2L_SMC5_chr9_72882890_ENST00000361138_IMMP2L_chr7_110603620_ENST00000447215_length(amino acids)=197AA_BP=1
MLQSYHLKLSFLSLIRKFLFHILFSFLPSLTISPSRAITLLMIFCSGFLGDNSISTMPLEHPLFTKNPTLSARPMKAGFPAKPRQMAHTM
LDFPVPLAPTIIFKWGPGDTSQISYVRKFSIEMRTIEPSTKGPDDCNSGSCGAEFFLLLGTSDEGSLGRALLEGWGLGVDVFLLGVAILA

--------------------------------------------------------------

>84018_84018_6_SMC5-IMMP2L_SMC5_chr9_72882890_ENST00000361138_IMMP2L_chr7_110603620_ENST00000452895_length(amino acids)=230AA_BP=135
MWDAEEARMATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMENFLTYDICEVSPGPHLNMIVGAN
GTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSRGMVEIELSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHH

--------------------------------------------------------------

>84018_84018_7_SMC5-IMMP2L_SMC5_chr9_72882891_ENST00000361138_IMMP2L_chr7_110603621_ENST00000331762_length(amino acids)=230AA_BP=135
MWDAEEARMATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMENFLTYDICEVSPGPHLNMIVGAN
GTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSRGMVEIELSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHH

--------------------------------------------------------------

>84018_84018_8_SMC5-IMMP2L_SMC5_chr9_72882891_ENST00000361138_IMMP2L_chr7_110603621_ENST00000405709_length(amino acids)=230AA_BP=135
MWDAEEARMATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMENFLTYDICEVSPGPHLNMIVGAN
GTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSRGMVEIELSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHH

--------------------------------------------------------------

>84018_84018_9_SMC5-IMMP2L_SMC5_chr9_72882891_ENST00000361138_IMMP2L_chr7_110603621_ENST00000415362_length(amino acids)=231AA_BP=135
MWDAEEARMATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMENFLTYDICEVSPGPHLNMIVGAN
GTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSRGMVEIELSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHH

--------------------------------------------------------------

>84018_84018_10_SMC5-IMMP2L_SMC5_chr9_72882891_ENST00000361138_IMMP2L_chr7_110603621_ENST00000437687_length(amino acids)=168AA_BP=1
MTISPSRAITLLMIFCSGFLGDNSISTMPLEHPLFTKNPTLSARPMKAGFPAKPRQMAHTMLDFPVPLAPTIIFKWGPGDTSQISYVRKF

--------------------------------------------------------------

>84018_84018_11_SMC5-IMMP2L_SMC5_chr9_72882891_ENST00000361138_IMMP2L_chr7_110603621_ENST00000447215_length(amino acids)=197AA_BP=1
MLQSYHLKLSFLSLIRKFLFHILFSFLPSLTISPSRAITLLMIFCSGFLGDNSISTMPLEHPLFTKNPTLSARPMKAGFPAKPRQMAHTM
LDFPVPLAPTIIFKWGPGDTSQISYVRKFSIEMRTIEPSTKGPDDCNSGSCGAEFFLLLGTSDEGSLGRALLEGWGLGVDVFLLGVAILA

--------------------------------------------------------------

>84018_84018_12_SMC5-IMMP2L_SMC5_chr9_72882891_ENST00000361138_IMMP2L_chr7_110603621_ENST00000452895_length(amino acids)=230AA_BP=135
MWDAEEARMATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMENFLTYDICEVSPGPHLNMIVGAN
GTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSRGMVEIELSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHH

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:72882891/chr7:110603621)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
SMC5 SLF2,FAM178A	IMMP2L Q96T52
1173	FUNCTION: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO. {ECO:0000269\|PubMed:15814844}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SMC5

chr9:72882890

chr7:110603620

ENST00000361138

80_87

126.66666666666667

1102.0

Nucleotide binding

ATP

Hgene

SMC5

chr9:72882891

chr7:110603621

ENST00000361138

80_87

126.66666666666667

1102.0

Nucleotide binding

ATP

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SMC5

chr9:72882890

chr7:110603620

ENST00000361138

207_445

126.66666666666667

1102.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SMC5

chr9:72882890

chr7:110603620

ENST00000361138

647_828

126.66666666666667

1102.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SMC5

chr9:72882890

chr7:110603620

ENST00000361138

888_927

126.66666666666667

1102.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SMC5

chr9:72882891

chr7:110603621

ENST00000361138

207_445

126.66666666666667

1102.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SMC5

chr9:72882891

chr7:110603621

ENST00000361138

647_828

126.66666666666667

1102.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SMC5

chr9:72882891

chr7:110603621

ENST00000361138

888_927

126.66666666666667

1102.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SMC5

chr9:72882890

chr7:110603620

ENST00000361138

991_1026

126.66666666666667

1102.0

Compositional bias

Note=Ala/Asp-rich (DA-box)

Hgene

SMC5

chr9:72882891

chr7:110603621

ENST00000361138

991_1026

126.66666666666667

1102.0

Compositional bias

Note=Ala/Asp-rich (DA-box)

Hgene

SMC5

chr9:72882890

chr7:110603620

ENST00000361138

446_646

126.66666666666667

1102.0

Region

Note=Flexible hinge

Hgene

SMC5

chr9:72882891

chr7:110603621

ENST00000361138

446_646

126.66666666666667

1102.0

Region

Note=Flexible hinge

Tgene

IMMP2L

chr9:72882890

chr7:110603620

ENST00000331762

19_37

79.66666666666667

176.0

Transmembrane

Helical

Tgene

IMMP2L

chr9:72882890

chr7:110603620

ENST00000405709

19_37

79.66666666666667

176.0

Transmembrane

Helical

Tgene

IMMP2L

chr9:72882890

chr7:110603620

ENST00000415362

19_37

79.66666666666667

176.0

Transmembrane

Helical

Tgene

IMMP2L

chr9:72882890

chr7:110603620

ENST00000437687

19_37

79.66666666666667

111.0

Transmembrane

Helical

Tgene

IMMP2L

chr9:72882890

chr7:110603620

ENST00000447215

19_37

79.66666666666667

111.0

Transmembrane

Helical

Tgene

IMMP2L

chr9:72882890

chr7:110603620

ENST00000452895

19_37

79.66666666666667

176.0

Transmembrane

Helical

Tgene

IMMP2L

chr9:72882891

chr7:110603621

ENST00000331762

19_37

79.66666666666667

176.0

Transmembrane

Helical

Tgene

IMMP2L

chr9:72882891

chr7:110603621

ENST00000405709

19_37

79.66666666666667

176.0

Transmembrane

Helical

Tgene

IMMP2L

chr9:72882891

chr7:110603621

ENST00000415362

19_37

79.66666666666667

176.0

Transmembrane

Helical

Tgene

IMMP2L

chr9:72882891

chr7:110603621

ENST00000437687

19_37

79.66666666666667

111.0

Transmembrane

Helical

Tgene

IMMP2L

chr9:72882891

chr7:110603621

ENST00000447215

19_37

79.66666666666667

111.0

Transmembrane

Helical

Tgene

IMMP2L

chr9:72882891

chr7:110603621

ENST00000452895

19_37

79.66666666666667

176.0

Transmembrane

Helical

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Fusion Protein Structures

PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.

Fusion protein PDB link (fusion AA seq ID in FusionPDB)

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

AA seq

Len(AA seq)

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pLDDT score distribution

pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

SMC5_pLDDT.png

IMMP2L_pLDDT.png

pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

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Ramachandran Plot of Fusion Protein Structure

Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.

Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
SMC5
IMMP2L

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs to SMC5-IMMP2L

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to SMC5-IMMP2L

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source