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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:STAT5A-ARNTL2

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: STAT5A-ARNTL2
FusionPDB ID: 87260
FusionGDB2.0 ID: 87260
HgeneTgene
Gene symbol

STAT5A

ARNTL2

Gene ID

6776

56938

Gene namesignal transducer and activator of transcription 5Aaryl hydrocarbon receptor nuclear translocator like 2
SynonymsMGF|STAT5BMAL2|CLIF|MOP9|PASD9|bHLHe6
Cytomap

17q21.2

12p11.23

Type of geneprotein-codingprotein-coding
Descriptionsignal transducer and activator of transcription 5Aepididymis secretory sperm binding proteinaryl hydrocarbon receptor nuclear translocator-like protein 2CYCLE-like factorPAS domain-containing protein 9basic-helix-loop-helix-PAS protein MOP9brain and muscle ARNT-like 2class E basic helix-loop-helix protein 6member of PAS protein 9transcrip
Modification date2020032720200313
UniProtAcc.

Q8WYA1

Ensembl transtripts involved in fusion geneENST idsENST00000345506, ENST00000452307, 
ENST00000546010, ENST00000588868, 
ENST00000590949, ENST00000587646, 
ENST00000539558, ENST00000542388, 
ENST00000261178, ENST00000266503, 
ENST00000311001, ENST00000395901, 
ENST00000544915, ENST00000546179, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score4 X 4 X 3=486 X 5 X 5=150
# samples 47
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/150*10)=-1.09953567355091
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: STAT5A [Title/Abstract] AND ARNTL2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)STAT5A(40447811)-ARNTL2(27538414), # samples:1
Anticipated loss of major functional domain due to fusion event.STAT5A-ARNTL2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
STAT5A-ARNTL2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
STAT5A-ARNTL2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
STAT5A-ARNTL2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSTAT5A

GO:0038026

reelin-mediated signaling pathway

29581031

TgeneARNTL2

GO:0006357

regulation of transcription by RNA polymerase II

12055078

TgeneARNTL2

GO:0007623

circadian rhythm

10864977

TgeneARNTL2

GO:0045893

positive regulation of transcription, DNA-templated

12738229

TgeneARNTL2

GO:0045944

positive regulation of transcription by RNA polymerase II

15147242


check buttonFusion gene breakpoints across STAT5A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARNTL2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-J2-A4AD-01ASTAT5Achr17

40447811

-ARNTL2chr12

27538414

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000345506STAT5Achr1740447811-ENST00000544915ARNTL2chr1227538414+539511926422618658
ENST00000345506STAT5Achr1740447811-ENST00000395901ARNTL2chr1227538414+262011926422618658
ENST00000345506STAT5Achr1740447811-ENST00000546179ARNTL2chr1227538414+252711926422441599
ENST00000345506STAT5Achr1740447811-ENST00000311001ARNTL2chr1227538414+262011926422618658
ENST00000345506STAT5Achr1740447811-ENST00000261178ARNTL2chr1227538414+267711926422618658
ENST00000345506STAT5Achr1740447811-ENST00000266503ARNTL2chr1227538414+298111926422618658
ENST00000590949STAT5Achr1740447811-ENST00000544915ARNTL2chr1227538414+549512927422718658
ENST00000590949STAT5Achr1740447811-ENST00000395901ARNTL2chr1227538414+272012927422718659
ENST00000590949STAT5Achr1740447811-ENST00000546179ARNTL2chr1227538414+262712927422541599
ENST00000590949STAT5Achr1740447811-ENST00000311001ARNTL2chr1227538414+272012927422718659
ENST00000590949STAT5Achr1740447811-ENST00000261178ARNTL2chr1227538414+277712927422718658
ENST00000590949STAT5Achr1740447811-ENST00000266503ARNTL2chr1227538414+308112927422718658
ENST00000546010STAT5Achr1740447811-ENST00000544915ARNTL2chr1227538414+51969935332419628
ENST00000546010STAT5Achr1740447811-ENST00000395901ARNTL2chr1227538414+24219935332419628
ENST00000546010STAT5Achr1740447811-ENST00000546179ARNTL2chr1227538414+23289935332242569
ENST00000546010STAT5Achr1740447811-ENST00000311001ARNTL2chr1227538414+24219935332419628
ENST00000546010STAT5Achr1740447811-ENST00000261178ARNTL2chr1227538414+24789935332419628
ENST00000546010STAT5Achr1740447811-ENST00000266503ARNTL2chr1227538414+27829935332419628
ENST00000452307STAT5Achr1740447811-ENST00000544915ARNTL2chr1227538414+48636601102086658
ENST00000452307STAT5Achr1740447811-ENST00000395901ARNTL2chr1227538414+20886601102086658
ENST00000452307STAT5Achr1740447811-ENST00000546179ARNTL2chr1227538414+19956601101909599
ENST00000452307STAT5Achr1740447811-ENST00000311001ARNTL2chr1227538414+20886601102086658
ENST00000452307STAT5Achr1740447811-ENST00000261178ARNTL2chr1227538414+21456601102086658
ENST00000452307STAT5Achr1740447811-ENST00000266503ARNTL2chr1227538414+24496601102086658
ENST00000588868STAT5Achr1740447811-ENST00000544915ARNTL2chr1227538414+4819616662042658
ENST00000588868STAT5Achr1740447811-ENST00000395901ARNTL2chr1227538414+2044616662042658
ENST00000588868STAT5Achr1740447811-ENST00000546179ARNTL2chr1227538414+1951616661865599
ENST00000588868STAT5Achr1740447811-ENST00000311001ARNTL2chr1227538414+2044616662042658
ENST00000588868STAT5Achr1740447811-ENST00000261178ARNTL2chr1227538414+2101616662042658
ENST00000588868STAT5Achr1740447811-ENST00000266503ARNTL2chr1227538414+2405616662042658

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000345506ENST00000544915STAT5Achr1740447811-ARNTL2chr1227538414+0.0015297570.99847025
ENST00000345506ENST00000395901STAT5Achr1740447811-ARNTL2chr1227538414+0.00737720.99262285
ENST00000345506ENST00000546179STAT5Achr1740447811-ARNTL2chr1227538414+0.0081688230.99183124
ENST00000345506ENST00000311001STAT5Achr1740447811-ARNTL2chr1227538414+0.00737720.99262285
ENST00000345506ENST00000261178STAT5Achr1740447811-ARNTL2chr1227538414+0.0063863290.99361366
ENST00000345506ENST00000266503STAT5Achr1740447811-ARNTL2chr1227538414+0.0039197120.99608034
ENST00000590949ENST00000544915STAT5Achr1740447811-ARNTL2chr1227538414+0.0013869250.998613
ENST00000590949ENST00000395901STAT5Achr1740447811-ARNTL2chr1227538414+0.0047694610.9952305
ENST00000590949ENST00000546179STAT5Achr1740447811-ARNTL2chr1227538414+0.0052527210.9947472
ENST00000590949ENST00000311001STAT5Achr1740447811-ARNTL2chr1227538414+0.0047694610.9952305
ENST00000590949ENST00000261178STAT5Achr1740447811-ARNTL2chr1227538414+0.0043027020.99569726
ENST00000590949ENST00000266503STAT5Achr1740447811-ARNTL2chr1227538414+0.0029723720.9970277
ENST00000546010ENST00000544915STAT5Achr1740447811-ARNTL2chr1227538414+0.0006229630.9993771
ENST00000546010ENST00000395901STAT5Achr1740447811-ARNTL2chr1227538414+0.0034249980.99657494
ENST00000546010ENST00000546179STAT5Achr1740447811-ARNTL2chr1227538414+0.0040769030.99592304
ENST00000546010ENST00000311001STAT5Achr1740447811-ARNTL2chr1227538414+0.0034249980.99657494
ENST00000546010ENST00000261178STAT5Achr1740447811-ARNTL2chr1227538414+0.0028843460.9971156
ENST00000546010ENST00000266503STAT5Achr1740447811-ARNTL2chr1227538414+0.0017258820.9982741
ENST00000452307ENST00000544915STAT5Achr1740447811-ARNTL2chr1227538414+0.0013056960.99869436
ENST00000452307ENST00000395901STAT5Achr1740447811-ARNTL2chr1227538414+0.0051174640.9948826
ENST00000452307ENST00000546179STAT5Achr1740447811-ARNTL2chr1227538414+0.0054021630.9945978
ENST00000452307ENST00000311001STAT5Achr1740447811-ARNTL2chr1227538414+0.0051174640.9948826
ENST00000452307ENST00000261178STAT5Achr1740447811-ARNTL2chr1227538414+0.0044812780.9955187
ENST00000452307ENST00000266503STAT5Achr1740447811-ARNTL2chr1227538414+0.0029955920.99700445
ENST00000588868ENST00000544915STAT5Achr1740447811-ARNTL2chr1227538414+0.0013028080.9986972
ENST00000588868ENST00000395901STAT5Achr1740447811-ARNTL2chr1227538414+0.0049947710.9950052
ENST00000588868ENST00000546179STAT5Achr1740447811-ARNTL2chr1227538414+0.0051524420.99484754
ENST00000588868ENST00000311001STAT5Achr1740447811-ARNTL2chr1227538414+0.0049947710.9950052
ENST00000588868ENST00000261178STAT5Achr1740447811-ARNTL2chr1227538414+0.0042596040.9957404
ENST00000588868ENST00000266503STAT5Achr1740447811-ARNTL2chr1227538414+0.0028484450.99715155

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>87260_87260_1_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000345506_ARNTL2_chr12_27538414_ENST00000261178_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_2_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000345506_ARNTL2_chr12_27538414_ENST00000266503_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_3_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000345506_ARNTL2_chr12_27538414_ENST00000311001_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_4_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000345506_ARNTL2_chr12_27538414_ENST00000395901_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_5_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000345506_ARNTL2_chr12_27538414_ENST00000544915_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_6_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000345506_ARNTL2_chr12_27538414_ENST00000546179_length(amino acids)=599AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT

--------------------------------------------------------------

>87260_87260_7_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000452307_ARNTL2_chr12_27538414_ENST00000261178_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_8_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000452307_ARNTL2_chr12_27538414_ENST00000266503_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_9_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000452307_ARNTL2_chr12_27538414_ENST00000311001_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_10_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000452307_ARNTL2_chr12_27538414_ENST00000395901_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_11_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000452307_ARNTL2_chr12_27538414_ENST00000544915_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_12_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000452307_ARNTL2_chr12_27538414_ENST00000546179_length(amino acids)=599AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT

--------------------------------------------------------------

>87260_87260_13_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000546010_ARNTL2_chr12_27538414_ENST00000261178_length(amino acids)=628AA_BP=153
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQGLTNSYVGSNYRPSFLQDNELRHLILK
TAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDISPREKLIDAKTGLQVHSNLHAGRTRVYSGS
RRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKKDNSNFTCLVAIGRLQPYIVPQNSGEINVKP
TEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKEKILTDSYKFRAKDGSFVTLKSQWFSFTNPW
TKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGTDIANEILDLQRLQSSSYLDDSSPTGLMKDT

--------------------------------------------------------------

>87260_87260_14_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000546010_ARNTL2_chr12_27538414_ENST00000266503_length(amino acids)=628AA_BP=153
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQGLTNSYVGSNYRPSFLQDNELRHLILK
TAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDISPREKLIDAKTGLQVHSNLHAGRTRVYSGS
RRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKKDNSNFTCLVAIGRLQPYIVPQNSGEINVKP
TEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKEKILTDSYKFRAKDGSFVTLKSQWFSFTNPW
TKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGTDIANEILDLQRLQSSSYLDDSSPTGLMKDT

--------------------------------------------------------------

>87260_87260_15_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000546010_ARNTL2_chr12_27538414_ENST00000311001_length(amino acids)=628AA_BP=153
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQGLTNSYVGSNYRPSFLQDNELRHLILK
TAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDISPREKLIDAKTGLQVHSNLHAGRTRVYSGS
RRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKKDNSNFTCLVAIGRLQPYIVPQNSGEINVKP
TEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKEKILTDSYKFRAKDGSFVTLKSQWFSFTNPW
TKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGTDIANEILDLQRLQSSSYLDDSSPTGLMKDT

--------------------------------------------------------------

>87260_87260_16_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000546010_ARNTL2_chr12_27538414_ENST00000395901_length(amino acids)=628AA_BP=153
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQGLTNSYVGSNYRPSFLQDNELRHLILK
TAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDISPREKLIDAKTGLQVHSNLHAGRTRVYSGS
RRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKKDNSNFTCLVAIGRLQPYIVPQNSGEINVKP
TEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKEKILTDSYKFRAKDGSFVTLKSQWFSFTNPW
TKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGTDIANEILDLQRLQSSSYLDDSSPTGLMKDT

--------------------------------------------------------------

>87260_87260_17_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000546010_ARNTL2_chr12_27538414_ENST00000544915_length(amino acids)=628AA_BP=153
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQGLTNSYVGSNYRPSFLQDNELRHLILK
TAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDISPREKLIDAKTGLQVHSNLHAGRTRVYSGS
RRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKKDNSNFTCLVAIGRLQPYIVPQNSGEINVKP
TEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKEKILTDSYKFRAKDGSFVTLKSQWFSFTNPW
TKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGTDIANEILDLQRLQSSSYLDDSSPTGLMKDT

--------------------------------------------------------------

>87260_87260_18_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000546010_ARNTL2_chr12_27538414_ENST00000546179_length(amino acids)=569AA_BP=153
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQGLTNSYVGSNYRPSFLQDNELRHLILK
TAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDISPREKLIDAKTGLQVHSNLHAGRTRVYSGS
RRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKKDNSNFTCLVAIGRLQPYIVPQNSGEINVKP
TEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKEKILTDSYKFRAKDGSFVTLKSQWFSFTNPW
TKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGTDIANEILDLQRLQSSSYLDDSSPTGLMKDT

--------------------------------------------------------------

>87260_87260_19_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000588868_ARNTL2_chr12_27538414_ENST00000261178_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_20_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000588868_ARNTL2_chr12_27538414_ENST00000266503_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_21_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000588868_ARNTL2_chr12_27538414_ENST00000311001_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_22_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000588868_ARNTL2_chr12_27538414_ENST00000395901_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_23_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000588868_ARNTL2_chr12_27538414_ENST00000544915_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_24_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000588868_ARNTL2_chr12_27538414_ENST00000546179_length(amino acids)=599AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT

--------------------------------------------------------------

>87260_87260_25_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000590949_ARNTL2_chr12_27538414_ENST00000261178_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_26_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000590949_ARNTL2_chr12_27538414_ENST00000266503_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_27_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000590949_ARNTL2_chr12_27538414_ENST00000311001_length(amino acids)=659AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_28_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000590949_ARNTL2_chr12_27538414_ENST00000395901_length(amino acids)=659AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_29_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000590949_ARNTL2_chr12_27538414_ENST00000544915_length(amino acids)=658AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT
DIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVNCRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFDALCDNDDT

--------------------------------------------------------------

>87260_87260_30_STAT5A-ARNTL2_STAT5A_chr17_40447811_ENST00000590949_ARNTL2_chr12_27538414_ENST00000546179_length(amino acids)=599AA_BP=183
MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHY
ATQLQKTYDRCPLELVRCIRHILYNEQRLVREANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDI
SPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKK
DNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKE
KILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGEASFLPCSSQSSEESSRQSCMSVPGMSTGTVLGAGSIGT

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:40447811/chr12:27538414)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ARNTL2

Q8WYA1

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers'). The predominant Zeitgeber for the central clock is light, which is sensed by retina and signals directly to the SCN. The central clock entrains the peripheral clocks through neuronal and hormonal signals, body temperature and feeding-related cues, aligning all clocks with the external light/dark cycle. Circadian rhythms allow an organism to achieve temporal homeostasis with its environment at the molecular level by regulating gene expression to create a peak of protein expression once every 24 hours to control when a particular physiological process is most active with respect to the solar day. Transcription and translation of core clock components (CLOCK, NPAS2, ARNTL/BMAL1, ARNTL2/BMAL2, PER1, PER2, PER3, CRY1 and CRY2) plays a critical role in rhythm generation, whereas delays imposed by post-translational modifications (PTMs) are important for determining the period (tau) of the rhythms (tau refers to the period of a rhythm and is the length, in time, of one complete cycle). A diurnal rhythm is synchronized with the day/night cycle, while the ultradian and infradian rhythms have a period shorter and longer than 24 hours, respectively. Disruptions in the circadian rhythms contribute to the pathology of cardiovascular diseases, cancer, metabolic syndromes and aging. A transcription/translation feedback loop (TTFL) forms the core of the molecular circadian clock mechanism. Transcription factors, CLOCK or NPAS2 and ARNTL/BMAL1 or ARNTL2/BMAL2, form the positive limb of the feedback loop, act in the form of a heterodimer and activate the transcription of core clock genes and clock-controlled genes (involved in key metabolic processes), harboring E-box elements (5'-CACGTG-3') within their promoters. The core clock genes: PER1/2/3 and CRY1/2 which are transcriptional repressors form the negative limb of the feedback loop and interact with the CLOCK|NPAS2-ARNTL/BMAL1|ARNTL2/BMAL2 heterodimer inhibiting its activity and thereby negatively regulating their own expression. This heterodimer also activates nuclear receptors NR1D1/2 and RORA/B/G, which form a second feedback loop and which activate and repress ARNTL/BMAL1 transcription, respectively. The CLOCK-ARNTL2/BMAL2 heterodimer activates the transcription of SERPINE1/PAI1 and BHLHE40/DEC1. {ECO:0000269|PubMed:11018023, ECO:0000269|PubMed:12738229, ECO:0000269|PubMed:14672706}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARNTL2chr17:40447811chr12:27538414ENST00000261178215178_250113.33333333333333589.0DomainPAS 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000261178215357_427113.33333333333333589.0DomainPAS 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000261178215432_475113.33333333333333589.0DomainNote=PAC
TgeneARNTL2chr17:40447811chr12:27538414ENST00000266503417178_250161.33333333333334637.0DomainPAS 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000266503417357_427161.33333333333334637.0DomainPAS 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000266503417432_475161.33333333333334637.0DomainNote=PAC
TgeneARNTL2chr17:40447811chr12:27538414ENST00000311001316178_250147.33333333333334623.0DomainPAS 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000311001316357_427147.33333333333334623.0DomainPAS 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000311001316432_475147.33333333333334623.0DomainNote=PAC
TgeneARNTL2chr17:40447811chr12:27538414ENST00000395901215178_250124.33333333333333600.0DomainPAS 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000395901215357_427124.33333333333333600.0DomainPAS 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000395901215432_475124.33333333333333600.0DomainNote=PAC
TgeneARNTL2chr17:40447811chr12:27538414ENST00000542388114107_16076.33333333333333552.0DomainbHLH
TgeneARNTL2chr17:40447811chr12:27538414ENST00000542388114178_25076.33333333333333552.0DomainPAS 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000542388114357_42776.33333333333333552.0DomainPAS 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000542388114432_47576.33333333333333552.0DomainNote=PAC
TgeneARNTL2chr17:40447811chr12:27538414ENST00000544915316178_250127.33333333333333603.0DomainPAS 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000544915316357_427127.33333333333333603.0DomainPAS 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000544915316432_475127.33333333333333603.0DomainNote=PAC
TgeneARNTL2chr17:40447811chr12:27538414ENST00000546179214178_250124.33333333333333541.0DomainPAS 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000546179214357_427124.33333333333333541.0DomainPAS 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000546179214432_475124.33333333333333541.0DomainNote=PAC
TgeneARNTL2chr17:40447811chr12:27538414ENST00000261178215177_187113.33333333333333589.0MotifNuclear export signal 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000261178215392_400113.33333333333333589.0MotifNuclear export signal 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000266503417177_187161.33333333333334637.0MotifNuclear export signal 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000266503417392_400161.33333333333334637.0MotifNuclear export signal 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000311001316177_187147.33333333333334623.0MotifNuclear export signal 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000311001316392_400147.33333333333334623.0MotifNuclear export signal 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000395901215177_187124.33333333333333600.0MotifNuclear export signal 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000395901215392_400124.33333333333333600.0MotifNuclear export signal 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000542388114177_18776.33333333333333552.0MotifNuclear export signal 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000542388114392_40076.33333333333333552.0MotifNuclear export signal 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000544915316177_187127.33333333333333603.0MotifNuclear export signal 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000544915316392_400127.33333333333333603.0MotifNuclear export signal 2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000546179214177_187124.33333333333333541.0MotifNuclear export signal 1
TgeneARNTL2chr17:40447811chr12:27538414ENST00000546179214392_400124.33333333333333541.0MotifNuclear export signal 2

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTAT5Achr17:40447811chr12:27538414ENST00000345506-620589_686183.33333333333334795.0DomainSH2
HgeneSTAT5Achr17:40447811chr12:27538414ENST00000546010-418589_686153.33333333333334765.0DomainSH2
HgeneSTAT5Achr17:40447811chr12:27538414ENST00000590949-519589_686183.33333333333334795.0DomainSH2
TgeneARNTL2chr17:40447811chr12:27538414ENST00000261178215107_160113.33333333333333589.0DomainbHLH
TgeneARNTL2chr17:40447811chr12:27538414ENST00000266503417107_160161.33333333333334637.0DomainbHLH
TgeneARNTL2chr17:40447811chr12:27538414ENST00000311001316107_160147.33333333333334623.0DomainbHLH
TgeneARNTL2chr17:40447811chr12:27538414ENST00000395901215107_160124.33333333333333600.0DomainbHLH
TgeneARNTL2chr17:40447811chr12:27538414ENST00000544915316107_160127.33333333333333603.0DomainbHLH
TgeneARNTL2chr17:40447811chr12:27538414ENST00000546179214107_160124.33333333333333541.0DomainbHLH
TgeneARNTL2chr17:40447811chr12:27538414ENST0000026117821549_54113.33333333333333589.0MotifNuclear localization signal
TgeneARNTL2chr17:40447811chr12:27538414ENST0000026650341749_54161.33333333333334637.0MotifNuclear localization signal
TgeneARNTL2chr17:40447811chr12:27538414ENST0000031100131649_54147.33333333333334623.0MotifNuclear localization signal
TgeneARNTL2chr17:40447811chr12:27538414ENST0000039590121549_54124.33333333333333600.0MotifNuclear localization signal
TgeneARNTL2chr17:40447811chr12:27538414ENST0000054238811449_5476.33333333333333552.0MotifNuclear localization signal
TgeneARNTL2chr17:40447811chr12:27538414ENST0000054491531649_54127.33333333333333603.0MotifNuclear localization signal
TgeneARNTL2chr17:40447811chr12:27538414ENST0000054617921449_54124.33333333333333541.0MotifNuclear localization signal


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
STAT5A
ARNTL2


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneARNTL2chr17:40447811chr12:27538414ENST0000026117821546_258113.33333333333333589.0PER2
TgeneARNTL2chr17:40447811chr12:27538414ENST0000026650341746_258161.33333333333334637.0PER2
TgeneARNTL2chr17:40447811chr12:27538414ENST0000031100131646_258147.33333333333334623.0PER2
TgeneARNTL2chr17:40447811chr12:27538414ENST0000039590121546_258124.33333333333333600.0PER2
TgeneARNTL2chr17:40447811chr12:27538414ENST0000054238811446_25876.33333333333333552.0PER2
TgeneARNTL2chr17:40447811chr12:27538414ENST0000054491531646_258127.33333333333333603.0PER2
TgeneARNTL2chr17:40447811chr12:27538414ENST0000054617921446_258124.33333333333333541.0PER2


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Related Drugs to STAT5A-ARNTL2


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to STAT5A-ARNTL2


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource