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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:SYCP2-BCL2L1

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: SYCP2-BCL2L1
	FusionPDB ID: 88332
	FusionGDB2.0 ID: 88332
		Hgene	Tgene
	Gene symbol	SYCP2	BCL2L1
	Gene ID	10388	598
	Gene name	synaptonemal complex protein 2	BCL2 like 1
	Synonyms	SCP-2\|SCP2\|SPGF1	BCL-XL/S\|BCL2L\|BCLX\|Bcl-X\|PPP1R52
	Cytomap	20q13.33	20q11.21
	Type of gene	protein-coding	protein-coding
	Description	synaptonemal complex protein 2synaptonemal complex lateral element protein	bcl-2-like protein 1apoptosis regulator Bcl-Xprotein phosphatase 1, regulatory subunit 52
	Modification date	20200313	20200327
	UniProtAcc	.	Q9BZR8
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000357552, ENST00000371001, ENST00000476314,	ENST00000307677, ENST00000376055, ENST00000420653, ENST00000376062,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	4 X 4 X 3=48	10 X 5 X 10=500
	# samples	5	11
	** MAII score	log2(5/48*10)=0.0588936890535686 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(11/500*10)=-2.18442457113743 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: SYCP2 [Title/Abstract] AND BCL2L1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	SYCP2(58440443)-BCL2L1(30253889), # samples:1
Anticipated loss of major functional domain due to fusion event.	SYCP2-BCL2L1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. SYCP2-BCL2L1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. SYCP2-BCL2L1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. SYCP2-BCL2L1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. SYCP2-BCL2L1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. SYCP2-BCL2L1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	BCL2L1	GO:0001836	release of cytochrome c from mitochondria	9843949
Tgene	BCL2L1	GO:0019050	suppression by virus of host apoptotic process	15231831
Tgene	BCL2L1	GO:0034097	response to cytokine	9184696
Tgene	BCL2L1	GO:0043066	negative regulation of apoptotic process	7650367\|9388232
Tgene	BCL2L1	GO:0046902	regulation of mitochondrial membrane permeability	9843949
Tgene	BCL2L1	GO:0051881	regulation of mitochondrial membrane potential	9843949
Tgene	BCL2L1	GO:1900118	negative regulation of execution phase of apoptosis	20673843
Tgene	BCL2L1	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	26582200
Tgene	BCL2L1	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	16608847
Tgene	BCL2L1	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	29507230
Tgene	BCL2L1	GO:1903077	negative regulation of protein localization to plasma membrane	21041309
Tgene	BCL2L1	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	12011449

Fusion gene breakpoints across SYCP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across BCL2L1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LIHC	TCGA-G3-A25X-01A	SYCP2	chr20	58440443	-	BCL2L1	chr20	30253889	-

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000357552	SYCP2	chr20	58440443	-	ENST00000376062	BCL2L1	chr20	30253889	-	6376	4741	151	4878	1575
ENST00000371001	SYCP2	chr20	58440443	-	ENST00000376055	BCL2L1	chr20	30253889	-	6289	4654	64	4791	1575
ENST00000371001	SYCP2	chr20	58440443	-	ENST00000420653	BCL2L1	chr20	30253889	-	6281	4654	64	4791	1575

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000357552	ENST00000376062	SYCP2	chr20	58440443	-	BCL2L1	chr20	30253889	-	0.000430277	0.9995697
ENST00000371001	ENST00000376055	SYCP2	chr20	58440443	-	BCL2L1	chr20	30253889	-	0.000380651	0.99961936
ENST00000371001	ENST00000420653	SYCP2	chr20	58440443	-	BCL2L1	chr20	30253889	-	0.000371849	0.9996282

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>88332_88332_1_SYCP2-BCL2L1_SYCP2_chr20_58440443_ENST00000357552_BCL2L1_chr20_30253889_ENST00000376062_length(amino acids)=1575AA_BP=1530
MEPRACLLVRCLFCLAFFFFLNEVKMPIRPDLQQLEKCIDDALRKNDFKPLKTLLQIDICEDVKIKCSKQFFHKVDNLICRELNKEDIHN
VSAILVSVGRCGKNISVLGQAGLLTMIKQGLIQKMVAWFEKSKDIIQSQGNSKDEAVLNMIEDLVDLLLVIHDVSDEGKKQVVESFVPRI
CSLVIDSRVNICIQQEIIKKMNAMLDKMPQDARKILSNQEMLILMSSMGERILDAGDYDLQVGIVEALCRMTTEKQRQELAHQWFSMDFI
AKAFKRIKDSEFETDCRIFLNLVNGMLGDKRRVFTFPCLSAFLDKYELQIPSDEKLEEFWIDFNLGSQTLSFYIAGDNDDHQWEAVTVPE
EKVQIYSIEVRESKKLLTIILKNTVKISKREGKELLLYFDASLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQILVPES
QISPVGEELVSLKEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNTSIPPRRRRIKPPLQ
MTSSAEKPSVSQTSENRVDNAASLKSRSSEGRHRRDNIDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDN
ICGNKIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQ
QQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQ
KKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNL
NGADDPIIKLGIQEFQATAKEACADRSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSKPQLID
YSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIH
SRMKTVKLPKKQQKVFCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPYPKTSS
LESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESP
HINENYIQSKREESHLASSLSKSSEGREKTWFDMPCDATHVSGPTQHLSRKRIYIEDNLSNSNEVEMEEKGERRANLLPKKLCKIEDADH
HIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMTYETYERLNSEFKRRNNIRHKMLSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQ
FIIIEELENFEKDSQSLKDLEKEFVDFWEKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCNTDSEETVFTSEMCLMKEDMKVLQDRLLKDM

--------------------------------------------------------------

>88332_88332_2_SYCP2-BCL2L1_SYCP2_chr20_58440443_ENST00000371001_BCL2L1_chr20_30253889_ENST00000376055_length(amino acids)=1575AA_BP=1530
MEPRACLLVRCLFCLAFFFFLNEVKMPIRPDLQQLEKCIDDALRKNDFKPLKTLLQIDICEDVKIKCSKQFFHKVDNLICRELNKEDIHN
VSAILVSVGRCGKNISVLGQAGLLTMIKQGLIQKMVAWFEKSKDIIQSQGNSKDEAVLNMIEDLVDLLLVIHDVSDEGKKQVVESFVPRI
CSLVIDSRVNICIQQEIIKKMNAMLDKMPQDARKILSNQEMLILMSSMGERILDAGDYDLQVGIVEALCRMTTEKQRQELAHQWFSMDFI
AKAFKRIKDSEFETDCRIFLNLVNGMLGDKRRVFTFPCLSAFLDKYELQIPSDEKLEEFWIDFNLGSQTLSFYIAGDNDDHQWEAVTVPE
EKVQIYSIEVRESKKLLTIILKNTVKISKREGKELLLYFDASLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQILVPES
QISPVGEELVSLKEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNTSIPPRRRRIKPPLQ
MTSSAEKPSVSQTSENRVDNAASLKSRSSEGRHRRDNIDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDN
ICGNKIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQ
QQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQ
KKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNL
NGADDPIIKLGIQEFQATAKEACADRSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSKPQLID
YSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIH
SRMKTVKLPKKQQKVFCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPYPKTSS
LESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESP
HINENYIQSKREESHLASSLSKSSEGREKTWFDMPCDATHVSGPTQHLSRKRIYIEDNLSNSNEVEMEEKGERRANLLPKKLCKIEDADH
HIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMTYETYERLNSEFKRRNNIRHKMLSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQ
FIIIEELENFEKDSQSLKDLEKEFVDFWEKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCNTDSEETVFTSEMCLMKEDMKVLQDRLLKDM

--------------------------------------------------------------

>88332_88332_3_SYCP2-BCL2L1_SYCP2_chr20_58440443_ENST00000371001_BCL2L1_chr20_30253889_ENST00000420653_length(amino acids)=1575AA_BP=1530
MEPRACLLVRCLFCLAFFFFLNEVKMPIRPDLQQLEKCIDDALRKNDFKPLKTLLQIDICEDVKIKCSKQFFHKVDNLICRELNKEDIHN
VSAILVSVGRCGKNISVLGQAGLLTMIKQGLIQKMVAWFEKSKDIIQSQGNSKDEAVLNMIEDLVDLLLVIHDVSDEGKKQVVESFVPRI
CSLVIDSRVNICIQQEIIKKMNAMLDKMPQDARKILSNQEMLILMSSMGERILDAGDYDLQVGIVEALCRMTTEKQRQELAHQWFSMDFI
AKAFKRIKDSEFETDCRIFLNLVNGMLGDKRRVFTFPCLSAFLDKYELQIPSDEKLEEFWIDFNLGSQTLSFYIAGDNDDHQWEAVTVPE
EKVQIYSIEVRESKKLLTIILKNTVKISKREGKELLLYFDASLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQILVPES
QISPVGEELVSLKEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNTSIPPRRRRIKPPLQ
MTSSAEKPSVSQTSENRVDNAASLKSRSSEGRHRRDNIDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDN
ICGNKIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQ
QQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQ
KKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNL
NGADDPIIKLGIQEFQATAKEACADRSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSKPQLID
YSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIH
SRMKTVKLPKKQQKVFCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPYPKTSS
LESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESP
HINENYIQSKREESHLASSLSKSSEGREKTWFDMPCDATHVSGPTQHLSRKRIYIEDNLSNSNEVEMEEKGERRANLLPKKLCKIEDADH
HIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMTYETYERLNSEFKRRNNIRHKMLSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQ
FIIIEELENFEKDSQSLKDLEKEFVDFWEKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCNTDSEETVFTSEMCLMKEDMKVLQDRLLKDM

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:58440443/chr20:30253889)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	BCL2L1 Q9BZR8
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.	FUNCTION: Plays a role in apoptosis.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SYCP2

chr20:58440443

chr20:30253889

ENST00000357552

655_660

1505.0

1531.0

Compositional bias

Note=Poly-Ser

Hgene

SYCP2

chr20:58440443

chr20:30253889

ENST00000371001

655_660

1505.0

1531.0

Compositional bias

Note=Poly-Ser

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000376055

129_148

125.0

171.0

Motif

Note=BH1

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000376055

180_195

125.0

171.0

Motif

Note=BH2

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000307677

210_226

188.0

234.0

Transmembrane

Helical

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000376055

210_226

125.0

171.0

Transmembrane

Helical

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000376062

210_226

188.0

234.0

Transmembrane

Helical

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000420653

210_226

188.0

234.0

Transmembrane

Helical

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000307677

129_148

188.0

234.0

Motif

Note=BH1

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000307677

180_195

188.0

234.0

Motif

Note=BH2

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000307677

4_24

188.0

234.0

Motif

Note=BH4

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000307677

86_100

188.0

234.0

Motif

Note=BH3

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000376055

4_24

125.0

171.0

Motif

Note=BH4

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000376055

86_100

125.0

171.0

Motif

Note=BH3

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000376062

129_148

188.0

234.0

Motif

Note=BH1

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000376062

180_195

188.0

234.0

Motif

Note=BH2

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000376062

4_24

188.0

234.0

Motif

Note=BH4

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000376062

86_100

188.0

234.0

Motif

Note=BH3

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000420653

129_148

188.0

234.0

Motif

Note=BH1

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000420653

180_195

188.0

234.0

Motif

Note=BH2

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000420653

4_24

188.0

234.0

Motif

Note=BH4

Tgene

BCL2L1

chr20:58440443

chr20:30253889

ENST00000420653

86_100

188.0

234.0

Motif

Note=BH3

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
SYCP2
BCL2L1

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs to SYCP2-BCL2L1

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to SYCP2-BCL2L1

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source