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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:BAZ2A-PRIM1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: BAZ2A-PRIM1
FusionPDB ID: 9047
FusionGDB2.0 ID: 9047
HgeneTgene
Gene symbol

BAZ2A

PRIM1

Gene ID

11176

5557

Gene namebromodomain adjacent to zinc finger domain 2ADNA primase subunit 1
SynonymsTIP5|WALp3p49
Cytomap

12q13.3

12q13.3

Type of geneprotein-codingprotein-coding
Descriptionbromodomain adjacent to zinc finger domain protein 2ATTF-I interacting peptide 5TTF-I-interacting protein 5transcription termination factor I-interacting protein 5DNA primase small subunitDNA primase 1DNA primase 49 kDa subunitDNA primase subunit 48primase (DNA) subunit 1primase p49 subunitprimase polypeptide 1, 49kDaprimase, DNA, polypeptide 1 (49kDa)
Modification date2020031320200313
UniProtAcc

Q9UIF9

.
Ensembl transtripts involved in fusion geneENST idsENST00000179765, ENST00000379441, 
ENST00000549884, ENST00000551812, 
ENST00000553222, 		ENST00000552408, 
ENST00000338193, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score16 X 18 X 8=230411 X 10 X 7=770
# samples 2013
** MAII scorelog2(20/2304*10)=-3.52606881166759
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/770*10)=-2.56634682255381
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: BAZ2A [Title/Abstract] AND PRIM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)BAZ2A(57006799)-PRIM1(57128029), # samples:2
Anticipated loss of major functional domain due to fusion event.BAZ2A-PRIM1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BAZ2A-PRIM1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BAZ2A-PRIM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BAZ2A-PRIM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BAZ2A-PRIM1 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
BAZ2A-PRIM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
BAZ2A-PRIM1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
BAZ2A-PRIM1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
BAZ2A-PRIM1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
BAZ2A-PRIM1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across BAZ2A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PRIM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-HQ-A2OE-01ABAZ2Achr12

57003520

-PRIM1chr12

57128029

-
ChimerDB4BRCATCGA-D8-A140-01ABAZ2Achr12

57006799

-PRIM1chr12

57128029

-
ChimerDB4LUSCTCGA-60-2709-01ABAZ2Achr12

57008798

-PRIM1chr12

57128029

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000379441BAZ2Achr1257006799-ENST00000338193PRIM1chr1257128029-14441232881350420
ENST00000551812BAZ2Achr1257006799-ENST00000338193PRIM1chr1257128029-154713351011453450
ENST00000379441BAZ2Achr1257008798-ENST00000338193PRIM1chr1257128029-103982788945285
ENST00000551812BAZ2Achr1257008798-ENST00000338193PRIM1chr1257128029-11429301011048315
ENST00000379441BAZ2Achr1257003520-ENST00000338193PRIM1chr1257128029-24012189882307739
ENST00000551812BAZ2Achr1257003520-ENST00000338193PRIM1chr1257128029-250422921012410769

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000379441ENST00000338193BAZ2Achr1257006799-PRIM1chr1257128029-0.0017351510.99826485
ENST00000551812ENST00000338193BAZ2Achr1257006799-PRIM1chr1257128029-0.0026546470.9973454
ENST00000379441ENST00000338193BAZ2Achr1257008798-PRIM1chr1257128029-0.0049695020.9950305
ENST00000551812ENST00000338193BAZ2Achr1257008798-PRIM1chr1257128029-0.0040281710.99597186
ENST00000379441ENST00000338193BAZ2Achr1257003520-PRIM1chr1257128029-0.0040552640.9959447
ENST00000551812ENST00000338193BAZ2Achr1257003520-PRIM1chr1257128029-0.0047093940.99529064

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>9047_9047_1_BAZ2A-PRIM1_BAZ2A_chr12_57003520_ENST00000379441_PRIM1_chr12_57128029_ENST00000338193_length(amino acids)=739AA_BP=700
MGGSNTNLYVKWRPKDSEELGGPSLELCQPDMEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLS
TVSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQYPLNGILGGSRQPSSPSHNTNLRAGSQEF
WANGTQSPMGLNFDSQELYDSFPDQNFEEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLELEEEQPELKMCGYNGSVPSVESLHQEVSVL
VPDPTVSCLDDPSHLPDQLEDTPILSEDSLEPFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQ
TSTSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQLHPATSPAVSPTTSPAVSLVVSPAASPEI
SPEVCPAASTVVSPAVFSVVSPASSAVLPAVSLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSG
DVMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRNVVHSVRREHFSFSPRMPVGDFFEERDTPE
GLQWVQLSAEEIPSRIQAITGKRGRPRNTEKAKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQDYKKTSLAPYVKVFEHFLEN

--------------------------------------------------------------

>9047_9047_2_BAZ2A-PRIM1_BAZ2A_chr12_57003520_ENST00000551812_PRIM1_chr12_57128029_ENST00000338193_length(amino acids)=769AA_BP=730
MGGSNTNLYVKWRPKDSEELGGPSLELCQPDMEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLS
TVSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQYPLNGILGGSRQPSSPSHNTNLRAGSQEF
WANGTQSPMGLNFDSQELYDSFPDQNFEVMPNGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLE
LEEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLEPFNSLAPEPVSGGLYGIDDTELMGAEDKL
PLEDSPVISALDCPSLNNATAFSLLADDSQTSTSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTI
QLHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAVSLEVPLTASVTSPKASPVTSPAAAFPTAS
PANKDVSSFLETTADVEEITGEGLTASGSGDVMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSR
NVVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEKAKTKEVPKVKRGRGRPPKVKITELLNKTD

--------------------------------------------------------------

>9047_9047_3_BAZ2A-PRIM1_BAZ2A_chr12_57006799_ENST00000379441_PRIM1_chr12_57128029_ENST00000338193_length(amino acids)=420AA_BP=330
MGGSNTNLYVKWRPKDSEELGGPSLELCQPDMEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLS
TVSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQYPLNGILGGSRQPSSPSHNTNLRAGSQEF
WANGTQSPMGLNFDSQELYDSFPDQNFEEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLELEEEQPELKMCGYNGSVPSVESLHQEVSVL
VPDPTVSCLDDPSHLPDQLEDTPILSEDSLEPFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQ

--------------------------------------------------------------

>9047_9047_4_BAZ2A-PRIM1_BAZ2A_chr12_57006799_ENST00000551812_PRIM1_chr12_57128029_ENST00000338193_length(amino acids)=450AA_BP=360
MGGSNTNLYVKWRPKDSEELGGPSLELCQPDMEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLS
TVSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQYPLNGILGGSRQPSSPSHNTNLRAGSQEF
WANGTQSPMGLNFDSQELYDSFPDQNFEVMPNGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLE
LEEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLEPFNSLAPEPVSGGLYGIDDTELMGAEDKL
PLEDSPVISALDCPSLNNATAFSLLADDSQTSTSIFASPTSPPVLGESVLQDYKKTSLAPYVKVFEHFLENLDKSRKGELLKKSDLQKDF

--------------------------------------------------------------

>9047_9047_5_BAZ2A-PRIM1_BAZ2A_chr12_57008798_ENST00000379441_PRIM1_chr12_57128029_ENST00000338193_length(amino acids)=285AA_BP=246
MGGSNTNLYVKWRPKDSEELGGPSLELCQPDMEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLS
TVSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQYPLNGILGGSRQPSSPSHNTNLRAGSQEF
WANGTQSPMGLNFDSQELYDSFPDQNFEEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLELEEEQPDYKKTSLAPYVKVFEHFLENLDKS

--------------------------------------------------------------

>9047_9047_6_BAZ2A-PRIM1_BAZ2A_chr12_57008798_ENST00000551812_PRIM1_chr12_57128029_ENST00000338193_length(amino acids)=315AA_BP=276
MGGSNTNLYVKWRPKDSEELGGPSLELCQPDMEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLS
TVSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQYPLNGILGGSRQPSSPSHNTNLRAGSQEF
WANGTQSPMGLNFDSQELYDSFPDQNFEVMPNGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLE

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:57006799/chr12:57128029)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BAZ2A

Q9UIF9

.
FUNCTION: Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity). {ECO:0000250}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-1029649_661699.33333333333341906.0DNA bindingNote=A.T hook 1
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-1029670_682699.33333333333341906.0DNA bindingNote=A.T hook 2
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-1029546_617699.33333333333341906.0DomainMBD

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-1029693_792699.33333333333341906.0Coiled coilOntology_term=ECO:0000255
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-529693_792380.33333333333331906.0Coiled coilOntology_term=ECO:0000255
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-329693_792245.333333333333341906.0Coiled coilOntology_term=ECO:0000255
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-10291212_1277699.33333333333341906.0Compositional biasNote=Glu-rich
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-10291290_1411699.33333333333341906.0Compositional biasNote=Pro-rich
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-10291759_1762699.33333333333341906.0Compositional biasNote=Poly-Arg
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-1029660_799699.33333333333341906.0Compositional biasNote=Lys-rich
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-5291212_1277380.33333333333331906.0Compositional biasNote=Glu-rich
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-5291290_1411380.33333333333331906.0Compositional biasNote=Pro-rich
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-5291759_1762380.33333333333331906.0Compositional biasNote=Poly-Arg
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-529660_799380.33333333333331906.0Compositional biasNote=Lys-rich
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-3291212_1277245.333333333333341906.0Compositional biasNote=Glu-rich
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-3291290_1411245.333333333333341906.0Compositional biasNote=Pro-rich
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-3291759_1762245.333333333333341906.0Compositional biasNote=Poly-Arg
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-329660_799245.333333333333341906.0Compositional biasNote=Lys-rich
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-10291186_1198699.33333333333341906.0DNA bindingNote=A.T hook 3
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-10291404_1416699.33333333333341906.0DNA bindingNote=A.T hook 4
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-5291186_1198380.33333333333331906.0DNA bindingNote=A.T hook 3
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-5291404_1416380.33333333333331906.0DNA bindingNote=A.T hook 4
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-529649_661380.33333333333331906.0DNA bindingNote=A.T hook 1
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-529670_682380.33333333333331906.0DNA bindingNote=A.T hook 2
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-3291186_1198245.333333333333341906.0DNA bindingNote=A.T hook 3
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-3291404_1416245.333333333333341906.0DNA bindingNote=A.T hook 4
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-329649_661245.333333333333341906.0DNA bindingNote=A.T hook 1
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-329670_682245.333333333333341906.0DNA bindingNote=A.T hook 2
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-10291810_1880699.33333333333341906.0DomainBromo
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-1029848_913699.33333333333341906.0DomainDDT
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-5291810_1880380.33333333333331906.0DomainBromo
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-529546_617380.33333333333331906.0DomainMBD
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-529848_913380.33333333333331906.0DomainDDT
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-3291810_1880245.333333333333341906.0DomainBromo
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-329546_617245.333333333333341906.0DomainMBD
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-329848_913245.333333333333341906.0DomainDDT
HgeneBAZ2Achr12:57003520chr12:57128029ENST00000551812-10291676_1726699.33333333333341906.0Zinc fingerPHD-type
HgeneBAZ2Achr12:57006799chr12:57128029ENST00000551812-5291676_1726380.33333333333331906.0Zinc fingerPHD-type
HgeneBAZ2Achr12:57008798chr12:57128029ENST00000551812-3291676_1726245.333333333333341906.0Zinc fingerPHD-type
TgenePRIM1chr12:57003520chr12:57128029ENST000003381931013121_131381.3333333333333421.0MotifNote=Zinc knuckle motif
TgenePRIM1chr12:57006799chr12:57128029ENST000003381931013121_131381.3333333333333421.0MotifNote=Zinc knuckle motif
TgenePRIM1chr12:57008798chr12:57128029ENST000003381931013121_131381.3333333333333421.0MotifNote=Zinc knuckle motif


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
BAZ2A
PRIM1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to BAZ2A-PRIM1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to BAZ2A-PRIM1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource