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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein Structure
	pLDDT scores
	Ramachandran Plot of Fusion Protein Structure
	Potential Active Site Information
	Potentially Interacting Small Molecules through Virtual Screening
	Biochemical Features of Small Molecules with ADME
	Drug Toxicity Information
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:TPM3-NTRK1

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: TPM3-NTRK1
	FusionPDB ID: 93385
	FusionGDB2.0 ID: 93385
		Hgene	Tgene
	Gene symbol	TPM3	NTRK1
	Gene ID	7170	4914
	Gene name	tropomyosin 3	neurotrophic receptor tyrosine kinase 1
	Synonyms	CAPM1\|CFTD\|HEL-189\|HEL-S-82p\|NEM1\|OK/SW-cl.5\|TM-5\|TM3\|TM30\|TM30nm\|TM5\|TPM3nu\|TPMsk3\|TRK\|hscp30	MTC\|TRK\|TRK1\|TRKA\|Trk-A\|p140-TrkA
	Cytomap	1q21.3	1q23.1
	Type of gene	protein-coding	protein-coding
	Description	tropomyosin alpha-3 chainalpha-tropomyosin, slow skeletalcytoskeletal tropomyosin TM30epididymis luminal protein 189epididymis secretory sperm binding protein Li 82pheat-stable cytoskeletal protein 30 kDatropomyosin 3 nutropomyosin gammatropomyosi	high affinity nerve growth factor receptorOncogene TRKTRK1-transforming tyrosine kinase proteingp140trkneurotrophic tyrosine kinase, receptor, type 1tropomyosin-related kinase Atyrosine kinase receptor A
	Modification date	20200328	20200313
	UniProtAcc	P06753	P04629
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000271850, ENST00000302206, ENST00000323144, ENST00000328159, ENST00000330188, ENST00000341372, ENST00000341485, ENST00000368530, ENST00000368531, ENST00000368533, ENST00000469717,	ENST00000531606, ENST00000358660, ENST00000368196, ENST00000392302, ENST00000524377,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	15 X 22 X 8=2640	25 X 24 X 13=7800
	# samples	24	33
	** MAII score	log2(24/2640*10)=-3.4594316186373 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(33/7800*10)=-4.56293619439116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: TPM3 [Title/Abstract] AND NTRK1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	TPM3(154142876)-NTRK1(156844363), # samples:4
Anticipated loss of major functional domain due to fusion event.	TPM3-NTRK1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. TPM3-NTRK1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. TPM3-NTRK1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. TPM3-NTRK1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. TPM3-NTRK1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. TPM3-NTRK1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. TPM3-NTRK1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. TPM3-NTRK1 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	NTRK1	GO:0006468	protein phosphorylation	15488758
Tgene	NTRK1	GO:0008285	negative regulation of cell proliferation	15488758
Tgene	NTRK1	GO:0010976	positive regulation of neuron projection development	15488758
Tgene	NTRK1	GO:0018108	peptidyl-tyrosine phosphorylation	2927393
Tgene	NTRK1	GO:0043547	positive regulation of GTPase activity	15488758
Tgene	NTRK1	GO:0046579	positive regulation of Ras protein signal transduction	15488758
Tgene	NTRK1	GO:0046777	protein autophosphorylation	15488758
Tgene	NTRK1	GO:0048011	neurotrophin TRK receptor signaling pathway	15488758
Tgene	NTRK1	GO:0051092	positive regulation of NF-kappaB transcription factor activity	15488758
Tgene	NTRK1	GO:0070374	positive regulation of ERK1 and ERK2 cascade	15488758
Tgene	NTRK1	GO:1904646	cellular response to amyloid-beta	11927634

Fusion gene breakpoints across TPM3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across NTRK1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-FD-A6TI-01A	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+
ChimerDB4	SARC	TCGA-DX-A3UA-01A	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+
ChimerDB4	SARC	TCGA-DX-A3UA	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+
ChimerDB4	SARC	TCGA-DX-A3UA	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+
ChimerDB4	THCA	TCGA-EL-A3D4-01A	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+
ChimerKB3	.	.	TPM3	chr1	152422287	-	NTRK1	chr1	155110984	+
ChimerKB3	.	.	TPM3	chr1	154143124	-	NTRK1	chr1	156844362	+
ChiTaRS5.0	N/A	M55336	TPM3	chr1	154155584	-	NTRK1	chr1	156845339	+
ChiTaRS5.0	N/A	M55337	TPM3	chr1	154155584	-	NTRK1	chr1	156845339	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000302206	TPM3	chr1	154143124	-	ENST00000392302	NTRK1	chr1	156844362	+	1880	532	606	1727	373
ENST00000302206	TPM3	chr1	154143124	-	ENST00000368196	NTRK1	chr1	156844362	+	1936	532	606	1727	373
ENST00000302206	TPM3	chr1	154143124	-	ENST00000524377	NTRK1	chr1	156844362	+	1728	532	606	1727	373
ENST00000302206	TPM3	chr1	154143124	-	ENST00000358660	NTRK1	chr1	156844362	+	1806	532	606	1736	376
ENST00000368533	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156844363	+	2065	717	53	1912	619
ENST00000368533	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156844363	+	2121	717	53	1912	619
ENST00000368533	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156844363	+	1913	717	53	1912	620
ENST00000368533	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156844363	+	1991	717	53	1921	622
ENST00000330188	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156844363	+	2098	750	86	1945	619
ENST00000330188	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156844363	+	2154	750	86	1945	619
ENST00000330188	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156844363	+	1946	750	86	1945	620
ENST00000330188	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156844363	+	2024	750	86	1954	622
ENST00000341485	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156844363	+	2053	705	89	1900	603
ENST00000341485	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156844363	+	2109	705	89	1900	603
ENST00000341485	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156844363	+	1901	705	89	1900	604
ENST00000341485	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156844363	+	1979	705	89	1909	606
ENST00000341372	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156844363	+	1999	651	62	1846	594
ENST00000341372	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156844363	+	2055	651	62	1846	594
ENST00000341372	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156844363	+	1847	651	62	1846	595
ENST00000341372	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156844363	+	1925	651	62	1855	597
ENST00000328159	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156844363	+	2012	664	0	1859	619
ENST00000328159	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156844363	+	2068	664	0	1859	619
ENST00000328159	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156844363	+	1860	664	0	1859	619
ENST00000328159	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156844363	+	1938	664	0	1868	622
ENST00000271850	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156844363	+	2163	815	34	2010	658
ENST00000271850	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156844363	+	2219	815	34	2010	658
ENST00000271850	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156844363	+	2011	815	34	2010	659
ENST00000271850	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156844363	+	2089	815	34	2019	661
ENST00000368531	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156844363	+	2023	675	11	1870	619
ENST00000368531	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156844363	+	2079	675	11	1870	619
ENST00000368531	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156844363	+	1871	675	11	1870	620
ENST00000368531	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156844363	+	1949	675	11	1879	622
ENST00000323144	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156844363	+	2057	709	45	1904	619
ENST00000323144	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156844363	+	2113	709	45	1904	619
ENST00000323144	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156844363	+	1905	709	45	1904	619
ENST00000323144	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156844363	+	1983	709	45	1913	622
ENST00000368530	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156844363	+	2316	968	187	2163	658
ENST00000368530	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156844363	+	2372	968	187	2163	658
ENST00000368530	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156844363	+	2164	968	187	2163	659
ENST00000368530	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156844363	+	2242	968	187	2172	661
ENST00000368533	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156845312	+	1906	717	53	1753	566
ENST00000368533	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156845312	+	1962	717	53	1753	566
ENST00000368533	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156845312	+	1754	717	53	1753	567
ENST00000368533	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156845312	+	1832	717	53	1762	569
ENST00000330188	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156845312	+	1939	750	86	1786	566
ENST00000330188	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156845312	+	1995	750	86	1786	566
ENST00000330188	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156845312	+	1787	750	86	1786	567
ENST00000330188	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156845312	+	1865	750	86	1795	569
ENST00000341485	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156845312	+	1894	705	89	1741	550
ENST00000341485	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156845312	+	1950	705	89	1741	550
ENST00000341485	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156845312	+	1742	705	89	1741	551
ENST00000341485	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156845312	+	1820	705	89	1750	553
ENST00000341372	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156845312	+	1840	651	62	1687	541
ENST00000341372	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156845312	+	1896	651	62	1687	541
ENST00000341372	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156845312	+	1688	651	62	1687	542
ENST00000341372	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156845312	+	1766	651	62	1696	544
ENST00000328159	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156845312	+	1853	664	0	1700	566
ENST00000328159	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156845312	+	1909	664	0	1700	566
ENST00000328159	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156845312	+	1701	664	0	1700	566
ENST00000328159	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156845312	+	1779	664	0	1709	569
ENST00000271850	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156845312	+	2004	815	34	1851	605
ENST00000271850	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156845312	+	2060	815	34	1851	605
ENST00000271850	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156845312	+	1852	815	34	1851	606
ENST00000271850	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156845312	+	1930	815	34	1860	608
ENST00000368531	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156845312	+	1864	675	11	1711	566
ENST00000368531	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156845312	+	1920	675	11	1711	566
ENST00000368531	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156845312	+	1712	675	11	1711	567
ENST00000368531	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156845312	+	1790	675	11	1720	569
ENST00000323144	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156845312	+	1898	709	45	1745	566
ENST00000323144	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156845312	+	1954	709	45	1745	566
ENST00000323144	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156845312	+	1746	709	45	1745	566
ENST00000323144	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156845312	+	1824	709	45	1754	569
ENST00000368530	TPM3	chr1	154142876	-	ENST00000392302	NTRK1	chr1	156845312	+	2157	968	187	2004	605
ENST00000368530	TPM3	chr1	154142876	-	ENST00000368196	NTRK1	chr1	156845312	+	2213	968	187	2004	605
ENST00000368530	TPM3	chr1	154142876	-	ENST00000524377	NTRK1	chr1	156845312	+	2005	968	187	2004	606
ENST00000368530	TPM3	chr1	154142876	-	ENST00000358660	NTRK1	chr1	156845312	+	2083	968	187	2013	608
ENST00000368533	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845311	+	1906	717	53	1753	566
ENST00000368533	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845311	+	1962	717	53	1753	566
ENST00000368533	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845311	+	1754	717	53	1753	567
ENST00000368533	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845311	+	1832	717	53	1762	569
ENST00000330188	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845311	+	1939	750	86	1786	566
ENST00000330188	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845311	+	1995	750	86	1786	566
ENST00000330188	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845311	+	1787	750	86	1786	567
ENST00000330188	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845311	+	1865	750	86	1795	569
ENST00000341485	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845311	+	1894	705	89	1741	550
ENST00000341485	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845311	+	1950	705	89	1741	550
ENST00000341485	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845311	+	1742	705	89	1741	551
ENST00000341485	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845311	+	1820	705	89	1750	553
ENST00000341372	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845311	+	1840	651	62	1687	541
ENST00000341372	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845311	+	1896	651	62	1687	541
ENST00000341372	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845311	+	1688	651	62	1687	542
ENST00000341372	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845311	+	1766	651	62	1696	544
ENST00000328159	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845311	+	1853	664	0	1700	566
ENST00000328159	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845311	+	1909	664	0	1700	566
ENST00000328159	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845311	+	1701	664	0	1700	566
ENST00000328159	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845311	+	1779	664	0	1709	569
ENST00000271850	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845311	+	2004	815	34	1851	605
ENST00000271850	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845311	+	2060	815	34	1851	605
ENST00000271850	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845311	+	1852	815	34	1851	606
ENST00000271850	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845311	+	1930	815	34	1860	608
ENST00000368531	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845311	+	1864	675	11	1711	566
ENST00000368531	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845311	+	1920	675	11	1711	566
ENST00000368531	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845311	+	1712	675	11	1711	567
ENST00000368531	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845311	+	1790	675	11	1720	569
ENST00000323144	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845311	+	1898	709	45	1745	566
ENST00000323144	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845311	+	1954	709	45	1745	566
ENST00000323144	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845311	+	1746	709	45	1745	566
ENST00000323144	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845311	+	1824	709	45	1754	569
ENST00000368530	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845311	+	2157	968	187	2004	605
ENST00000368530	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845311	+	2213	968	187	2004	605
ENST00000368530	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845311	+	2005	968	187	2004	606
ENST00000368530	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845311	+	2083	968	187	2013	608
ENST00000368533	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845871	+	1759	717	53	1606	517
ENST00000368533	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845871	+	1815	717	53	1606	517
ENST00000368533	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845871	+	1607	717	53	1606	518
ENST00000368533	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845871	+	1676	717	53	1606	517
ENST00000330188	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845871	+	1792	750	86	1639	517
ENST00000330188	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845871	+	1848	750	86	1639	517
ENST00000330188	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845871	+	1640	750	86	1639	518
ENST00000330188	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845871	+	1709	750	86	1639	517
ENST00000341485	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845871	+	1747	705	89	1594	501
ENST00000341485	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845871	+	1803	705	89	1594	501
ENST00000341485	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845871	+	1595	705	89	1594	502
ENST00000341485	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845871	+	1664	705	89	1594	501
ENST00000341372	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845871	+	1693	651	62	1540	492
ENST00000341372	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845871	+	1749	651	62	1540	492
ENST00000341372	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845871	+	1541	651	62	1540	493
ENST00000341372	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845871	+	1610	651	62	1540	492
ENST00000328159	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845871	+	1706	664	0	1553	517
ENST00000328159	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845871	+	1762	664	0	1553	517
ENST00000328159	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845871	+	1554	664	0	1553	517
ENST00000328159	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845871	+	1623	664	0	1553	517
ENST00000271850	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845871	+	1857	815	34	1704	556
ENST00000271850	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845871	+	1913	815	34	1704	556
ENST00000271850	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845871	+	1705	815	34	1704	557
ENST00000271850	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845871	+	1774	815	34	1704	556
ENST00000368531	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845871	+	1717	675	11	1564	517
ENST00000368531	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845871	+	1773	675	11	1564	517
ENST00000368531	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845871	+	1565	675	11	1564	518
ENST00000368531	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845871	+	1634	675	11	1564	517
ENST00000323144	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845871	+	1751	709	45	1598	517
ENST00000323144	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845871	+	1807	709	45	1598	517
ENST00000323144	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845871	+	1599	709	45	1598	517
ENST00000323144	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845871	+	1668	709	45	1598	517
ENST00000368530	TPM3	chr1	154142875	-	ENST00000392302	NTRK1	chr1	156845871	+	2010	968	187	1857	556
ENST00000368530	TPM3	chr1	154142875	-	ENST00000368196	NTRK1	chr1	156845871	+	2066	968	187	1857	556
ENST00000368530	TPM3	chr1	154142875	-	ENST00000524377	NTRK1	chr1	156845871	+	1858	968	187	1857	557
ENST00000368530	TPM3	chr1	154142875	-	ENST00000358660	NTRK1	chr1	156845871	+	1927	968	187	1857	556

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000368533	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.013049512	0.98695046
ENST00000368533	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.012576977	0.98742306
ENST00000368533	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.012748213	0.98725176
ENST00000368533	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.012450943	0.98754907
ENST00000330188	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.01321825	0.9867818
ENST00000330188	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.012732104	0.9872679
ENST00000330188	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.013084471	0.98691547
ENST00000330188	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.012641598	0.9873584
ENST00000341485	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.011970823	0.9880292
ENST00000341485	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.011594417	0.9884056
ENST00000341485	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.011322442	0.98867756
ENST00000341485	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.012487466	0.9875125
ENST00000341372	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.008624724	0.99137527
ENST00000341372	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.008295167	0.9917048
ENST00000341372	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.008934915	0.9910651
ENST00000341372	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.009093377	0.9909066
ENST00000328159	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.01219977	0.98780024
ENST00000328159	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.011827006	0.98817295
ENST00000328159	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.012216036	0.98778397
ENST00000328159	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.011860859	0.9881392
ENST00000271850	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.008865949	0.9911341
ENST00000271850	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.008594883	0.9914051
ENST00000271850	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.008504424	0.9914956
ENST00000271850	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.009043949	0.990956
ENST00000368531	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.011952227	0.98804784
ENST00000368531	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.011652621	0.98834735
ENST00000368531	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.012075979	0.98792404
ENST00000368531	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.011719914	0.98828006
ENST00000323144	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.013125354	0.98687464
ENST00000323144	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.012619168	0.98738086
ENST00000323144	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.013026797	0.9869732
ENST00000323144	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.012560636	0.98743933
ENST00000368530	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.009718122	0.9902818
ENST00000368530	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.009318773	0.99068123
ENST00000368530	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.009751187	0.99024886
ENST00000368530	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156844363	+	0.010482006	0.989518
ENST00000368533	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009879314	0.99012065
ENST00000368533	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009542638	0.9904573
ENST00000368533	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009687988	0.990312
ENST00000368533	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.010994527	0.9890055
ENST00000330188	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.010278128	0.98972183
ENST00000330188	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009876968	0.990123
ENST00000330188	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.010614105	0.98938584
ENST00000330188	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.011659377	0.9883406
ENST00000341485	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.00945276	0.99054724
ENST00000341485	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.00919983	0.9908002
ENST00000341485	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009340187	0.9906598
ENST00000341485	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009200151	0.99079984
ENST00000341372	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.008185676	0.9918143
ENST00000341372	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.007858476	0.9921415
ENST00000341372	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.007573832	0.99242616
ENST00000341372	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.008374361	0.9916257
ENST00000328159	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009769008	0.990231
ENST00000328159	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009451822	0.9905482
ENST00000328159	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009217746	0.9907823
ENST00000328159	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.010821654	0.9891783
ENST00000271850	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.006042903	0.99395704
ENST00000271850	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.005945774	0.99405426
ENST00000271850	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.00596277	0.9940373
ENST00000271850	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.006500893	0.99349916
ENST00000368531	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009723093	0.99027693
ENST00000368531	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009376534	0.9906234
ENST00000368531	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.009102908	0.9908971
ENST00000368531	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.010797353	0.9892027
ENST00000323144	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.010485414	0.9895146
ENST00000323144	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.010027723	0.98997223
ENST00000323144	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.01038064	0.9896193
ENST00000323144	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.011637682	0.9883624
ENST00000368530	ENST00000392302	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.006900759	0.9930992
ENST00000368530	ENST00000368196	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.006644499	0.9933555
ENST00000368530	ENST00000524377	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.006784597	0.99321544
ENST00000368530	ENST00000358660	TPM3	chr1	154142876	-	NTRK1	chr1	156845312	+	0.007563656	0.99243635
ENST00000368533	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009879314	0.99012065
ENST00000368533	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009542638	0.9904573
ENST00000368533	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009687988	0.990312
ENST00000368533	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.010994527	0.9890055
ENST00000330188	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.010278128	0.98972183
ENST00000330188	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009876968	0.990123
ENST00000330188	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.010614105	0.98938584
ENST00000330188	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.011659377	0.9883406
ENST00000341485	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.00945276	0.99054724
ENST00000341485	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.00919983	0.9908002
ENST00000341485	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009340187	0.9906598
ENST00000341485	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009200151	0.99079984
ENST00000341372	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.008185676	0.9918143
ENST00000341372	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.007858476	0.9921415
ENST00000341372	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.007573832	0.99242616
ENST00000341372	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.008374361	0.9916257
ENST00000328159	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009769008	0.990231
ENST00000328159	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009451822	0.9905482
ENST00000328159	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009217746	0.9907823
ENST00000328159	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.010821654	0.9891783
ENST00000271850	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.006042903	0.99395704
ENST00000271850	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.005945774	0.99405426
ENST00000271850	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.00596277	0.9940373
ENST00000271850	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.006500893	0.99349916
ENST00000368531	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009723093	0.99027693
ENST00000368531	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009376534	0.9906234
ENST00000368531	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.009102908	0.9908971
ENST00000368531	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.010797353	0.9892027
ENST00000323144	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.010485414	0.9895146
ENST00000323144	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.010027723	0.98997223
ENST00000323144	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.01038064	0.9896193
ENST00000323144	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.011637682	0.9883624
ENST00000368530	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.006900759	0.9930992
ENST00000368530	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.006644499	0.9933555
ENST00000368530	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.006784597	0.99321544
ENST00000368530	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845311	+	0.007563656	0.99243635
ENST00000368533	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007774983	0.99222505
ENST00000368533	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007333431	0.99266654
ENST00000368533	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007812809	0.99218714
ENST00000368533	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007347266	0.99265265
ENST00000330188	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.008598889	0.99140114
ENST00000330188	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007897699	0.9921023
ENST00000330188	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.008842953	0.99115705
ENST00000330188	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.008228978	0.99177104
ENST00000341485	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.006691741	0.9933082
ENST00000341485	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.006208628	0.9937914
ENST00000341485	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.006346167	0.9936538
ENST00000341485	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.006213028	0.99378693
ENST00000341372	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.006360445	0.9936395
ENST00000341372	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.006086513	0.9939135
ENST00000341372	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.006209526	0.99379045
ENST00000341372	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.005931438	0.9940686
ENST00000328159	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007550181	0.9924499
ENST00000328159	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007288422	0.99271154
ENST00000328159	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007622613	0.9923774
ENST00000328159	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007051928	0.99294806
ENST00000271850	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.004814345	0.9951857
ENST00000271850	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.004633473	0.9953666
ENST00000271850	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.004777675	0.9952224
ENST00000271850	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.004548646	0.9954514
ENST00000368531	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.00753506	0.9924649
ENST00000368531	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007270349	0.9927296
ENST00000368531	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007517917	0.992482
ENST00000368531	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007029873	0.99297017
ENST00000323144	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.008515767	0.9914842
ENST00000323144	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.007862116	0.99213785
ENST00000323144	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.00876821	0.99123174
ENST00000323144	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.008075357	0.9919247
ENST00000368530	ENST00000392302	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.005668571	0.99433136
ENST00000368530	ENST00000368196	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.005473045	0.9945269
ENST00000368530	ENST00000524377	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.005778578	0.9942214
ENST00000368530	ENST00000358660	TPM3	chr1	154142875	-	NTRK1	chr1	156845871	+	0.005432119	0.9945679

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>93385_93385_1_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000271850_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=608AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKE
ASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGM
VYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPW

--------------------------------------------------------------

>93385_93385_2_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000271850_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=605AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_3_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000271850_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=605AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_4_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000271850_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=606AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_5_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000271850_NTRK1_chr1_156845871_ENST00000358660_length(amino acids)=556AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDI
VLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRF
LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLP
IRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHAR

--------------------------------------------------------------

>93385_93385_6_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000271850_NTRK1_chr1_156845871_ENST00000368196_length(amino acids)=556AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDI
VLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRF
LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLP
IRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHAR

--------------------------------------------------------------

>93385_93385_7_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000271850_NTRK1_chr1_156845871_ENST00000392302_length(amino acids)=556AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDI
VLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRF
LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLP
IRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHAR

--------------------------------------------------------------

>93385_93385_8_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000271850_NTRK1_chr1_156845871_ENST00000524377_length(amino acids)=557AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDI
VLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRF
LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLP
IRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHAR

--------------------------------------------------------------

>93385_93385_9_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000323144_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=569AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
SPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLM
VFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS
TDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQRE

--------------------------------------------------------------

>93385_93385_10_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000323144_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_11_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000323144_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_12_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000323144_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_13_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000323144_NTRK1_chr1_156845871_ENST00000358660_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_14_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000323144_NTRK1_chr1_156845871_ENST00000368196_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_15_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000323144_NTRK1_chr1_156845871_ENST00000392302_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_16_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000323144_NTRK1_chr1_156845871_ENST00000524377_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_17_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000328159_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=569AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
SPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLM
VFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS
TDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQRE

--------------------------------------------------------------

>93385_93385_18_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000328159_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_19_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000328159_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_20_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000328159_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_21_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000328159_NTRK1_chr1_156845871_ENST00000358660_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_22_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000328159_NTRK1_chr1_156845871_ENST00000368196_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_23_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000328159_NTRK1_chr1_156845871_ENST00000392302_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_24_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000328159_NTRK1_chr1_156845871_ENST00000524377_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_25_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000330188_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=569AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
SPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLM
VFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS
TDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQRE

--------------------------------------------------------------

>93385_93385_26_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000330188_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_27_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000330188_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_28_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000330188_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=567AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_29_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000330188_NTRK1_chr1_156845871_ENST00000358660_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_30_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000330188_NTRK1_chr1_156845871_ENST00000368196_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_31_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000330188_NTRK1_chr1_156845871_ENST00000392302_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_32_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000330188_NTRK1_chr1_156845871_ENST00000524377_length(amino acids)=518AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_33_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341372_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=544AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFG
KVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLA
GGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYR
KFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYL

--------------------------------------------------------------

>93385_93385_34_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341372_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=541AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVF
LAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGE
DVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFT
TESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVL

--------------------------------------------------------------

>93385_93385_35_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341372_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=541AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVF
LAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGE
DVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFT
TESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVL

--------------------------------------------------------------

>93385_93385_36_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341372_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=542AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVF
LAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGE
DVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFT
TESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVL

--------------------------------------------------------------

>93385_93385_37_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341372_NTRK1_chr1_156845871_ENST00000358660_length(amino acids)=492AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVR
FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV
KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPP

--------------------------------------------------------------

>93385_93385_38_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341372_NTRK1_chr1_156845871_ENST00000368196_length(amino acids)=492AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVR
FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV
KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPP

--------------------------------------------------------------

>93385_93385_39_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341372_NTRK1_chr1_156845871_ENST00000392302_length(amino acids)=492AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVR
FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV
KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPP

--------------------------------------------------------------

>93385_93385_40_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341372_NTRK1_chr1_156845871_ENST00000524377_length(amino acids)=493AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVR
FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV
KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPP

--------------------------------------------------------------

>93385_93385_41_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341485_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=553AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLK
WELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS
HGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRW
MPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQA

--------------------------------------------------------------

>93385_93385_42_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341485_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=550AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWEL
GEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGP
DAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPP
ESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQ

--------------------------------------------------------------

>93385_93385_43_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341485_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=550AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWEL
GEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGP
DAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPP
ESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQ

--------------------------------------------------------------

>93385_93385_44_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341485_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=551AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWEL
GEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGP
DAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPP
ESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQ

--------------------------------------------------------------

>93385_93385_45_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341485_NTRK1_chr1_156845871_ENST00000358660_length(amino acids)=501AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLT
MLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRN
CLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRE

--------------------------------------------------------------

>93385_93385_46_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341485_NTRK1_chr1_156845871_ENST00000368196_length(amino acids)=501AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLT
MLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRN
CLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRE

--------------------------------------------------------------

>93385_93385_47_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341485_NTRK1_chr1_156845871_ENST00000392302_length(amino acids)=501AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLT
MLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRN
CLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRE

--------------------------------------------------------------

>93385_93385_48_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000341485_NTRK1_chr1_156845871_ENST00000524377_length(amino acids)=502AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLT
MLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRN
CLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRE

--------------------------------------------------------------

>93385_93385_49_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368530_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=608AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKE
ASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGM
VYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPW

--------------------------------------------------------------

>93385_93385_50_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368530_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=605AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_51_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368530_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=605AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_52_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368530_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=606AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_53_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368530_NTRK1_chr1_156845871_ENST00000358660_length(amino acids)=556AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDI
VLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRF
LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLP
IRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHAR

--------------------------------------------------------------

>93385_93385_54_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368530_NTRK1_chr1_156845871_ENST00000368196_length(amino acids)=556AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDI
VLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRF
LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLP
IRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHAR

--------------------------------------------------------------

>93385_93385_55_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368530_NTRK1_chr1_156845871_ENST00000392302_length(amino acids)=556AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDI
VLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRF
LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLP
IRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHAR

--------------------------------------------------------------

>93385_93385_56_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368530_NTRK1_chr1_156845871_ENST00000524377_length(amino acids)=557AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDI
VLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRF
LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLP
IRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHAR

--------------------------------------------------------------

>93385_93385_57_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368531_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=569AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
SPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLM
VFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS
TDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQRE

--------------------------------------------------------------

>93385_93385_58_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368531_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_59_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368531_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_60_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368531_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=567AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_61_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368531_NTRK1_chr1_156845871_ENST00000358660_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_62_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368531_NTRK1_chr1_156845871_ENST00000368196_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_63_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368531_NTRK1_chr1_156845871_ENST00000392302_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_64_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368531_NTRK1_chr1_156845871_ENST00000524377_length(amino acids)=518AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_65_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368533_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=569AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
SPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLM
VFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS
TDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQRE

--------------------------------------------------------------

>93385_93385_66_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368533_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_67_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368533_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_68_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368533_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=567AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_69_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368533_NTRK1_chr1_156845871_ENST00000358660_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_70_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368533_NTRK1_chr1_156845871_ENST00000368196_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_71_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368533_NTRK1_chr1_156845871_ENST00000392302_length(amino acids)=517AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_72_TPM3-NTRK1_TPM3_chr1_154142875_ENST00000368533_NTRK1_chr1_156845871_ENST00000524377_length(amino acids)=518AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>93385_93385_73_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000271850_NTRK1_chr1_156844363_ENST00000358660_length(amino acids)=661AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPV
EKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFS
DASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPL
LMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDI
YSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQ

--------------------------------------------------------------

>93385_93385_74_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000271850_NTRK1_chr1_156844363_ENST00000368196_length(amino acids)=658AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPV
EKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFS
DACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMV
FEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYST
DYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREP

--------------------------------------------------------------

>93385_93385_75_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000271850_NTRK1_chr1_156844363_ENST00000392302_length(amino acids)=658AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPV
EKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFS
DACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMV
FEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYST
DYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREP

--------------------------------------------------------------

>93385_93385_76_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000271850_NTRK1_chr1_156844363_ENST00000524377_length(amino acids)=659AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPV
EKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFS
DACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMV
FEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYST
DYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREP

--------------------------------------------------------------

>93385_93385_77_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000271850_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=608AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKE
ASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGM
VYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPW

--------------------------------------------------------------

>93385_93385_78_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000271850_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=605AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_79_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000271850_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=605AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_80_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000271850_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=606AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_81_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000323144_NTRK1_chr1_156844363_ENST00000358660_length(amino acids)=622AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLP
EQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL
GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFG

--------------------------------------------------------------

>93385_93385_82_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000323144_NTRK1_chr1_156844363_ENST00000368196_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_83_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000323144_NTRK1_chr1_156844363_ENST00000392302_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_84_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000323144_NTRK1_chr1_156844363_ENST00000524377_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_85_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000323144_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=569AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
SPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLM
VFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS
TDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQRE

--------------------------------------------------------------

>93385_93385_86_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000323144_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_87_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000323144_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_88_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000323144_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_89_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000328159_NTRK1_chr1_156844363_ENST00000358660_length(amino acids)=622AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLP
EQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL
GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFG

--------------------------------------------------------------

>93385_93385_90_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000328159_NTRK1_chr1_156844363_ENST00000368196_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_91_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000328159_NTRK1_chr1_156844363_ENST00000392302_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_92_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000328159_NTRK1_chr1_156844363_ENST00000524377_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_93_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000328159_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=569AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
SPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLM
VFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS
TDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQRE

--------------------------------------------------------------

>93385_93385_94_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000328159_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_95_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000328159_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_96_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000328159_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_97_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000330188_NTRK1_chr1_156844363_ENST00000358660_length(amino acids)=622AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLP
EQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL
GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFG

--------------------------------------------------------------

>93385_93385_98_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000330188_NTRK1_chr1_156844363_ENST00000368196_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_99_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000330188_NTRK1_chr1_156844363_ENST00000392302_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_100_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000330188_NTRK1_chr1_156844363_ENST00000524377_length(amino acids)=620AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_101_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000330188_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=569AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
SPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLM
VFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS
TDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQRE

--------------------------------------------------------------

>93385_93385_102_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000330188_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_103_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000330188_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_104_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000330188_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=567AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_105_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341372_NTRK1_chr1_156844363_ENST00000358660_length(amino acids)=597AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLG
GSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQR
EAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHR
DLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDC

--------------------------------------------------------------

>93385_93385_106_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341372_NTRK1_chr1_156844363_ENST00000368196_length(amino acids)=594AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLG
GSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAE
LLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLA
TRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQ

--------------------------------------------------------------

>93385_93385_107_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341372_NTRK1_chr1_156844363_ENST00000392302_length(amino acids)=594AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLG
GSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAE
LLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLA
TRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQ

--------------------------------------------------------------

>93385_93385_108_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341372_NTRK1_chr1_156844363_ENST00000524377_length(amino acids)=595AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLG
GSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAE
LLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLA
TRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQ

--------------------------------------------------------------

>93385_93385_109_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341372_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=544AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFG
KVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLA
GGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYR
KFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYL

--------------------------------------------------------------

>93385_93385_110_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341372_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=541AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVF
LAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGE
DVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFT
TESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVL

--------------------------------------------------------------

>93385_93385_111_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341372_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=541AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVF
LAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGE
DVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFT
TESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVL

--------------------------------------------------------------

>93385_93385_112_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341372_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=542AA_BP=196
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGESRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEA
KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEF
AERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVF
LAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGE
DVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFT
TESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVL

--------------------------------------------------------------

>93385_93385_113_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341485_NTRK1_chr1_156844363_ENST00000358660_length(amino acids)=606AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLA
MSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEAS
ESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVY
LAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQ

--------------------------------------------------------------

>93385_93385_114_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341485_NTRK1_chr1_156844363_ENST00000368196_length(amino acids)=603AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLA
MSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESA
RQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAG
LHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSN

--------------------------------------------------------------

>93385_93385_115_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341485_NTRK1_chr1_156844363_ENST00000392302_length(amino acids)=603AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLA
MSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESA
RQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAG
LHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSN

--------------------------------------------------------------

>93385_93385_116_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341485_NTRK1_chr1_156844363_ENST00000524377_length(amino acids)=604AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLA
MSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESA
RQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAG
LHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSN

--------------------------------------------------------------

>93385_93385_117_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341485_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=553AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLK
WELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS
HGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRW
MPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQA

--------------------------------------------------------------

>93385_93385_118_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341485_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=550AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWEL
GEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGP
DAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPP
ESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQ

--------------------------------------------------------------

>93385_93385_119_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341485_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=550AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWEL
GEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGP
DAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPP
ESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQ

--------------------------------------------------------------

>93385_93385_120_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000341485_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=551AA_BP=205
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADEEKME
LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKL
KEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWEL
GEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGP
DAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPP
ESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQ

--------------------------------------------------------------

>93385_93385_121_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368530_NTRK1_chr1_156844363_ENST00000358660_length(amino acids)=661AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPV
EKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFS
DASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPL
LMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDI
YSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQ

--------------------------------------------------------------

>93385_93385_122_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368530_NTRK1_chr1_156844363_ENST00000368196_length(amino acids)=658AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPV
EKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFS
DACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMV
FEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYST
DYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREP

--------------------------------------------------------------

>93385_93385_123_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368530_NTRK1_chr1_156844363_ENST00000392302_length(amino acids)=658AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPV
EKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFS
DACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMV
FEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYST
DYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREP

--------------------------------------------------------------

>93385_93385_124_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368530_NTRK1_chr1_156844363_ENST00000524377_length(amino acids)=659AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPV
EKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFS
DACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMV
FEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYST
DYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREP

--------------------------------------------------------------

>93385_93385_125_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368530_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=608AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKE
ASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGM
VYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPW

--------------------------------------------------------------

>93385_93385_126_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368530_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=605AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_127_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368530_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=605AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_128_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368530_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=606AA_BP=260
MLMMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS
LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE
RTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDG
LAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE
SARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYL
AGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQL

--------------------------------------------------------------

>93385_93385_129_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368531_NTRK1_chr1_156844363_ENST00000358660_length(amino acids)=622AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLP
EQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL
GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFG

--------------------------------------------------------------

>93385_93385_130_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368531_NTRK1_chr1_156844363_ENST00000368196_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_131_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368531_NTRK1_chr1_156844363_ENST00000392302_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_132_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368531_NTRK1_chr1_156844363_ENST00000524377_length(amino acids)=620AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_133_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368531_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=569AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
SPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLM
VFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS
TDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQRE

--------------------------------------------------------------

>93385_93385_134_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368531_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_135_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368531_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_136_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368531_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=567AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_137_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368533_NTRK1_chr1_156844363_ENST00000358660_length(amino acids)=622AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLP
EQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGL
GQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFG

--------------------------------------------------------------

>93385_93385_138_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368533_NTRK1_chr1_156844363_ENST00000368196_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_139_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368533_NTRK1_chr1_156844363_ENST00000392302_length(amino acids)=619AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_140_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368533_NTRK1_chr1_156844363_ENST00000524377_length(amino acids)=620AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNK
FGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQD
KMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL
LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVL

--------------------------------------------------------------

>93385_93385_141_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368533_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=569AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
SPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLM
VFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS
TDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQRE

--------------------------------------------------------------

>93385_93385_142_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368533_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_143_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368533_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=566AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_144_TPM3-NTRK1_TPM3_chr1_154142876_ENST00000368533_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=567AA_BP=221
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG
MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDA
CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFE
YMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY
YRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ

--------------------------------------------------------------

>93385_93385_145_TPM3-NTRK1_TPM3_chr1_154143124_ENST00000302206_NTRK1_chr1_156844362_ENST00000358660_length(amino acids)=376AA_BP=
MAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDI
VLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRF
LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLP
IRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHAR

--------------------------------------------------------------

>93385_93385_146_TPM3-NTRK1_TPM3_chr1_154143124_ENST00000302206_NTRK1_chr1_156844362_ENST00000368196_length(amino acids)=373AA_BP=
MAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLK
WELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS
HGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRW
MPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQA

--------------------------------------------------------------

>93385_93385_147_TPM3-NTRK1_TPM3_chr1_154143124_ENST00000302206_NTRK1_chr1_156844362_ENST00000392302_length(amino acids)=373AA_BP=
MAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLK
WELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS
HGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRW
MPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQA

--------------------------------------------------------------

>93385_93385_148_TPM3-NTRK1_TPM3_chr1_154143124_ENST00000302206_NTRK1_chr1_156844362_ENST00000524377_length(amino acids)=373AA_BP=
MAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLK
WELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS
HGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRW
MPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQA

--------------------------------------------------------------

Top

Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:154142876/chr1:156844363)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
TPM3 P06753	NTRK1 P04629
FUNCTION: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. {ECO:0000250\|UniProtKB:P09493}.	FUNCTION: Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand (PubMed:1850821, PubMed:1849459, PubMed:1281417, PubMed:8325889, PubMed:15488758, PubMed:22649032, PubMed:17196528, PubMed:27445338). Can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival (By similarity). Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation (PubMed:1281417). Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. {ECO:0000250\|UniProtKB:P35739, ECO:0000250\|UniProtKB:Q3UFB7, ECO:0000269\|PubMed:11244088, ECO:0000269\|PubMed:1281417, ECO:0000269\|PubMed:15488758, ECO:0000269\|PubMed:17196528, ECO:0000269\|PubMed:1849459, ECO:0000269\|PubMed:1850821, ECO:0000269\|PubMed:22649032, ECO:0000269\|PubMed:27445338, ECO:0000269\|PubMed:27676246, ECO:0000269\|PubMed:8155326, ECO:0000269\|PubMed:8325889}.; FUNCTION: [Isoform TrkA-III]: Resistant to NGF, it constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed. {ECO:0000269\|PubMed:15488758}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

510_781

445.3333333333333

791.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

510_781

415.3333333333333

761.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

510_781

451.3333333333333

797.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

510_781

494.3333333333333

791.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

510_781

464.3333333333333

761.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

510_781

500.3333333333333

797.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

510_781

392.3333333333333

791.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

510_781

362.3333333333333

761.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

510_781

398.3333333333333

797.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

510_781

445.3333333333333

791.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

510_781

415.3333333333333

761.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

510_781

451.3333333333333

797.0

Domain

Protein kinase

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

537_541

445.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

607_611

445.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

537_541

415.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

607_611

415.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

537_541

451.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

607_611

451.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

537_541

494.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

607_611

494.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

537_541

464.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

607_611

464.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

537_541

500.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

607_611

500.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

537_541

392.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

607_611

392.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

537_541

362.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

607_611

362.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

537_541

398.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

607_611

398.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

537_541

445.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

607_611

445.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

537_541

415.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

607_611

415.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

537_541

451.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

607_611

451.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

516_524

445.3333333333333

791.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

516_524

415.3333333333333

761.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

516_524

451.3333333333333

797.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

516_524

494.3333333333333

791.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

516_524

464.3333333333333

761.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

516_524

500.3333333333333

797.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

516_524

392.3333333333333

791.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

516_524

362.3333333333333

761.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

516_524

398.3333333333333

797.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

516_524

445.3333333333333

791.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

516_524

415.3333333333333

761.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

516_524

451.3333333333333

797.0

Nucleotide binding

ATP

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

440_796

415.3333333333333

761.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

440_796

392.3333333333333

791.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

440_796

362.3333333333333

761.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

440_796

398.3333333333333

797.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

440_796

415.3333333333333

761.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

424_439

415.3333333333333

761.0

Transmembrane

Helical

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

424_439

392.3333333333333

791.0

Transmembrane

Helical

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

424_439

362.3333333333333

761.0

Transmembrane

Helical

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

424_439

398.3333333333333

797.0

Transmembrane

Helical

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

424_439

415.3333333333333

761.0

Transmembrane

Helical

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TPM3

chr1:154142875

chr1:156845311

ENST00000323144

1_285

221.33333333333334

248.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142875

chr1:156845311

ENST00000330188

1_285

221.33333333333334

249.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142875

chr1:156845311

ENST00000368530

1_285

258.3333333333333

286.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142875

chr1:156845311

ENST00000368531

1_285

221.33333333333334

248.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142875

chr1:156845311

ENST00000368533

1_285

221.33333333333334

249.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142875

chr1:156845871

ENST00000323144

1_285

221.33333333333334

248.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142875

chr1:156845871

ENST00000330188

1_285

221.33333333333334

249.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142875

chr1:156845871

ENST00000368530

1_285

258.3333333333333

286.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142875

chr1:156845871

ENST00000368531

1_285

221.33333333333334

248.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142875

chr1:156845871

ENST00000368533

1_285

221.33333333333334

249.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142876

chr1:156844363

ENST00000323144

1_285

221.33333333333334

248.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142876

chr1:156844363

ENST00000330188

1_285

221.33333333333334

249.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142876

chr1:156844363

ENST00000368530

1_285

258.3333333333333

286.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142876

chr1:156844363

ENST00000368531

1_285

221.33333333333334

248.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142876

chr1:156844363

ENST00000368533

1_285

221.33333333333334

249.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142876

chr1:156845312

ENST00000323144

1_285

221.33333333333334

248.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142876

chr1:156845312

ENST00000330188

1_285

221.33333333333334

249.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142876

chr1:156845312

ENST00000368530

1_285

258.3333333333333

286.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142876

chr1:156845312

ENST00000368531

1_285

221.33333333333334

248.0

Coiled coil

Ontology_term=ECO:0000250

Hgene

TPM3

chr1:154142876

chr1:156845312

ENST00000368533

1_285

221.33333333333334

249.0

Coiled coil

Ontology_term=ECO:0000250

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

148_193

445.3333333333333

791.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

194_283

445.3333333333333

791.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

299_365

445.3333333333333

791.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

148_193

415.3333333333333

761.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

194_283

415.3333333333333

761.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

299_365

415.3333333333333

761.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

148_193

451.3333333333333

797.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

194_283

451.3333333333333

797.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

299_365

451.3333333333333

797.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

148_193

494.3333333333333

791.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

194_283

494.3333333333333

791.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

299_365

494.3333333333333

791.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

148_193

464.3333333333333

761.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

194_283

464.3333333333333

761.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

299_365

464.3333333333333

761.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

148_193

500.3333333333333

797.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

194_283

500.3333333333333

797.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

299_365

500.3333333333333

797.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

148_193

392.3333333333333

791.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

194_283

392.3333333333333

791.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

299_365

392.3333333333333

791.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

148_193

362.3333333333333

761.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

194_283

362.3333333333333

761.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

299_365

362.3333333333333

761.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

148_193

398.3333333333333

797.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

194_283

398.3333333333333

797.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

299_365

398.3333333333333

797.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

148_193

445.3333333333333

791.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

194_283

445.3333333333333

791.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

299_365

445.3333333333333

791.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

148_193

415.3333333333333

761.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

194_283

415.3333333333333

761.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

299_365

415.3333333333333

761.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

148_193

451.3333333333333

797.0

Domain

Note=LRRCT

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

194_283

451.3333333333333

797.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

299_365

451.3333333333333

797.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

116_137

445.3333333333333

791.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

90_113

445.3333333333333

791.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

116_137

415.3333333333333

761.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

90_113

415.3333333333333

761.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

116_137

451.3333333333333

797.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

90_113

451.3333333333333

797.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

116_137

494.3333333333333

791.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

90_113

494.3333333333333

791.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

116_137

464.3333333333333

761.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

90_113

464.3333333333333

761.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

116_137

500.3333333333333

797.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

90_113

500.3333333333333

797.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

116_137

392.3333333333333

791.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

90_113

392.3333333333333

791.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

116_137

362.3333333333333

761.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

90_113

362.3333333333333

761.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

116_137

398.3333333333333

797.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

90_113

398.3333333333333

797.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

116_137

445.3333333333333

791.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

90_113

445.3333333333333

791.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

116_137

415.3333333333333

761.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

90_113

415.3333333333333

761.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

116_137

451.3333333333333

797.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

90_113

451.3333333333333

797.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

33_423

445.3333333333333

791.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

440_796

445.3333333333333

791.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000392302

33_423

415.3333333333333

761.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

33_423

451.3333333333333

797.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

440_796

451.3333333333333

797.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

33_423

494.3333333333333

791.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

440_796

494.3333333333333

791.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

33_423

464.3333333333333

761.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

440_796

464.3333333333333

761.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

33_423

500.3333333333333

797.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

440_796

500.3333333333333

797.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000368196

33_423

392.3333333333333

791.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000392302

33_423

362.3333333333333

761.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142876

chr1:156844363

ENST00000524377

33_423

398.3333333333333

797.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

33_423

445.3333333333333

791.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

440_796

445.3333333333333

791.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000392302

33_423

415.3333333333333

761.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

33_423

451.3333333333333

797.0

Topological domain

Extracellular

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

440_796

451.3333333333333

797.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000368196

424_439

445.3333333333333

791.0

Transmembrane

Helical

Tgene

NTRK1

chr1:154142875

chr1:156845311

ENST00000524377

424_439

451.3333333333333

797.0

Transmembrane

Helical

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000368196

424_439

494.3333333333333

791.0

Transmembrane

Helical

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000392302

424_439

464.3333333333333

761.0

Transmembrane

Helical

Tgene

NTRK1

chr1:154142875

chr1:156845871

ENST00000524377

424_439

500.3333333333333

797.0

Transmembrane

Helical

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000368196

424_439

445.3333333333333

791.0

Transmembrane

Helical

Tgene

NTRK1

chr1:154142876

chr1:156845312

ENST00000524377

424_439

451.3333333333333

797.0

Transmembrane

Helical

Top

Fusion Protein Structures

PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.

Fusion protein PDB link (fusion AA seq ID in FusionPDB)	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	AA seq	Len(AA seq)

PDB file (129) >>>129.pdbFusion protein BP residue: CIF file (129) >>>129.cif	TPM3	chr1	154143124	-	NTRK1	chr1	156844362	+	MAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGG SSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGK VFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIV RFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLG LGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSR DIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTY GKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHS	373
3D view using mol* of 129 (AA BP:)


PDB file (133) >>>133.pdbFusion protein BP residue: CIF file (133) >>>133.cif	TPM3	chr1	154143124	-	NTRK1	chr1	156844362	+	MAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGG SSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGA FGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQ HIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPG PLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFG MSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEI FTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQ	376
3D view using mol* of 133 (AA BP:)

Top

pLDDT score distribution

pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

TPM3_pLDDT.png

NTRK1_pLDDT.png

pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

TPM3_NTRK1_129_PAE.png (AA BP:)

TPM3_NTRK1_129_pLDDT.png (AA BP:)

TPM3_NTRK1_129_pLDDT_and_active_sites.png (AA BP:)

TPM3_NTRK1_129_violinplot.png (AA BP:)

TPM3_NTRK1_133_PAE.png (AA BP:)

TPM3_NTRK1_133_pLDDT.png (AA BP:)

TPM3_NTRK1_133_pLDDT_and_active_sites.png (AA BP:)

TPM3_NTRK1_133_violinplot.png (AA BP:)

Top

Ramachandran Plot of Fusion Protein Structure

Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.

Fusion AA seq ID in FusionPDB and their Ramachandran plots

TPM3_NTRK1_133.png

Top

Potential Active Site Information

The potential binding sites of these fusion proteins were identified using SiteMap, a module of the Schrodinger suite.

Fusion AA seq ID in FusionPDB	Site score	Size	D score	Volume	Exposure	Enclosure	Contact	Phobic	Philic	Balance	Don/Acc	Residues
129	1.036	251	1.065	979.265	0.636	0.726	0.867	0.687	0.953	0.721	1.113	Chain A: 45,46,47,64,65,66,67,68,69,70,73,74,97,98 ,121,123,124,125,129,130,133,134,136,137,140,141,1 44,149,150,164,166,218,223,224,225,226,227,232,243 ,244,245,246,247,250,257,260,261,263,264,265,266,2 67,276,277,278,279,280,281
133	1.105	181	1.068	422.919	0.487	0.855	1.17	1.071	1.179	0.908	0.881	Chain A: 39,41,42,43,44,46,47,48,49,50,51,69,74,99 ,100,101,102,104,124,126,127,128,130,132,133,135,1 36,137,139,140,143,144,167,169,230,234,235,248,249 ,250,251,252,253,256,260

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Potentially Interacting Small Molecules through Virtual Screening

The FDA-approved small molecule library molecules were subjected to virtual screening using the Glide.

Fusion AA seq ID in FusionPDB

ZINC ID

DrugBank ID

Drug name

Docking score

Glide gscore

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Drug information from DrugBank of the top 20 interacting small molecules.

ZINC ID

DrugBank ID

Drug name

Drug type

SMILES

Drug group

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Biochemical Features of Small Molecules

ADME (Absorption, Distribution, Metabolism, and Excretion) of drugs using QikProp(v3.9)

ZINC ID

mol_MW

dipole

SASA

FOSA

FISA

PISA

WPSA

volume

donorHB

accptHB

Human Oral Absorption

Percent Human Oral Absorption

Rule Of Five

Rule Of Three

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Drug Toxicity Information

Toxicity information of individual drugs using eToxPred

ZINC ID

Smile

Surface Accessibility

Toxicity

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene	PPI interactors
NTRK1	ABL1, NGF, MATK, PLCG1, GRB2, CAV1, NTF3, SQSTM1, SH2B1, SHC1, SH2B2, ARHGAP32, FRS2, NTRK1, RAP1A, SHC3, GIPC1, RGS19, PTPN1, TRAF6, NEDD4, CBL, HSP90AA1, HSPA4, CDC37, NEDD4L, MYC, SGSM3, SORBS1, TNK2, SNX17, SNX27, GAREML, SOS2, PIK3CA, GAREM, PIK3C2B, ARHGEF40, PIK3R1, PIK3R2, SOS1, PIK3CB, PML, UBC, AMFR, CBLB, GAB1, EPN1, PIK3C2A, ANKRD13A, DOCK4, TRIO, LGR5, WRNIP1, RABEP1, PDGFRA, KANK2, RABGEF1, VAV2, TBC1D15, PTPN11, GAK, IRS2, PCDHGC3, EPS15, LRRN3, HUWE1, ACVR1B, MIB1, OFD1, PIBF1, ZNF497, TXN, CAT, FABP3, JUP, DSG1, TGM1, CFL1, LCN1, HIST2H4A, DSP, PFN1, LGALS3BP, HIST1H2BL, LTF, S100A9, IGLL5, TGM3, DSC1, LYZ, DCD, LEKR1, ENO2, PPIA, BTN1A1, XRCC5, XRCC6, HLA-A, GSTP1, ABCB7, PA2G4, PRDX1, HDGF, HSPA4L, TBC1D10B, HP1BP3, KIF26B, SYT4, RHOBTB3, NOTCH3, GAB2, ATAD3A, RBM15B, KCNH2, USP15, PDCD11, RBFOX2, RBM14, RNF31, ADNP, ZC3HAV1, MAP7D1, USP4, JAK1, PTPRS, PDGFRB, HIST1H1C, USP11, PPFIBP1, INTS6, VGF, ARHGEF11, SMPD4, SYNPO2, HNRNPM, SLC27A4, DDX41, EGFR, H1FX, ASAP1, HIST1H1B, RRBP1, EPHA2, KIDINS220, CPT1A, UNC5B, IGF1R, DDR2, AUP1, XPR1, RP9, MARK2, REPS1, EMD, SMARCA4, DDX21, DAB2IP, C7, MSTO1, CDC27, ZNF629, ASAP2, NCAPH2, SRBD1, ATAD3B, TCF12, PLEKHA6, INPPL1, PRPF4B, DPM1, SMARCA1, FIP1L1, DLGAP5, PLEKHH3, TRA2A, ACIN1, DDX10, TAX1BP1, SMARCA5, RABEP2, DDX5, MYO1C, SRSF10, DNAJA2, RET, TRA2B, MYEF2, PNPLA6, SLC12A2, TAF6L, RSL1D1, ARAP3, DDX18, ABL2, KHDRBS1, CERK, SRSF7, SPTLC2, PBXIP1, DNAJA1, IQGAP3, DDX31, ZC3H11A, PLRG1, CNP, FMR1, HIP1R, KIAA1429, CDC5L, ARAP1, ZNF316, SMARCC2, EML5, VANGL2, SLC25A1, UNC5C, SLC16A1, RFC1, ZKSCAN1, CHD1, PTK7, SMARCD2, AP3B1, YTHDC2, AKAP8L, RPL15, CTNND1, PHLDB1, ZNF574, DDX27, TOM1, RASA1, MORC2, MTCH2, IMMT, SMARCC1, ROR2, CAPN2, DNAJC11, SYT11, AP2A1, LBR, MEPCE, NCAPD3, CEP97, QKI, LRRC41, LPCAT2, EPS15L1, LAS1L, TMEM131, CWF19L2, NCAPG2, MAP4K5, CCP110, ARHGEF2, ITGAV, ZC3H18, CWC22, VIM, FAM171A1, TMEM132A, SRSF9, SOGA1, NKRF, RBL1, FMNL3, TOP1, PIGT, RBM15, GBAS, EDC3, WDR5, NOP2, GNL2, SLC25A11, RRP1B, FAM115A, INTS5, SLC25A5, AAK1, HERC5, CCNT1, FERMT2, CDC42BPA, MRPL28, UBAP2, WWP2, SEC24B, HNRNPU, GPD2, FXR2, DHX15, SLC25A22, SSR1, PLXNB2, PROX1, TEX10, USP19, FTSJ3, TMEM59, GTF3C2, PGAM5, CPSF1, KLHL22, TMX3, SIN3A, NOP58, PTCD3, RPRD2, DHX9, PICALM, FARP1, SLC25A6, ERLIN2, SMARCD1, RHOT1, ALDH1B1, SGPL1, USP9X, HNRNPF, KIAA1211, MAPK7, DDX17, GSE1, DVL3, MRPL44, DNAJB6, GTPBP4, HNRNPA0, PLXNA4, SFXN3, NAT10, DDX28, SNW1, MYO6, MRPL24, PRRT4, FAM98A, PURA, DHX29, C1QBP, TRIP4, TBK1, RBM28, ZNF609, POLRMT, PCDHB3, XRN1, HSD17B11, DKC1, DHX30, CDK13, SENP3, LPHN2, GPATCH4, NDUFA9, RASA4, MCCC1, DDX24, RPL14, RPS8, ATG2B, MYO1B, PTPN12, CEBPZ, ILVBL, RALY, KIF14, ZC3H7A, MOV10, MAP4K4, DHX57, RBMX, FXR1, MRPS35, SART1, MARK3, DECR1, CCDC88A, ANKLE2, PRPF31, LARP7, RPL10, PACS1, RPL13, FAM120A, SLC25A13, ADAR, CDK1, HNRNPR, CSNK1E, DLG1, LEMD3, NOL9, IFT122, NCLN, STK11IP, GATAD2B, CHERP, LARP4, MAP3K1, HNRNPUL2, PPIL2, ESYT2, MYH10, RPL8, UQCRC2, NDUFA10, HAX1, HELLS, MED14, RBM42, CHCHD3, RPL7, ABCD3, TUBGCP6, MRPS9, SNRNP200, IGF2BP3, LRCH3, MRPL3, RSBN1L, SAFB, TUBG1, ALDH16A1, ARHGEF12, EPB41L5, AP2A2, SRSF6, HLTF, PTPLAD1, TMPO, AGO2, POP1, RPS9, HDAC6, ILF3, VWA8, ABCB1, SCRIB, GTF3C5, YBX1, RBM4, PTPN9, PRPF8, BRD3, TRIM24, CLASP2, MADD, TCF4, MAP4K3, TSC2, DDX23, RPL7A, RRP12, PRKD2, TRMT1L, EDC4, CSTF3, RPS2, NDUFS2, RPL13A, PTPRR, ATP7A, EXD2, IK, HIP1, MATR3, IGSF3, PTPRF, SPATA5L1, EFTUD2, RPS3A, TUBGCP5, TTN, GIT1, PATL1, NUP160, PDE4B, SUN2, PTPN23, RPS6, DCP1A, CDC73, MEX3A, EIF2AK2, RPL3, PPP1R10, SRP72, ELAVL3, NOM1, RPL18, CEP170, THRAP3, MED17, MRPS7, DDX20, PDPR, SH3PXD2A, DBN1, DAP3, OAS3, STT3B, COPE, MED12, AP3D1, CAPRIN1, PHB2, U2SURP, BSG, TECR, FARSA, HSD17B12, RPL4, HNRNPUL1, PPFIA1, MRPS22, TBL3, GNL3, MTA2, CPSF2, ATP2B1, AP3B2, PPIP5K2, DDX56, ASCC3, FMNL2, SMCHD1, MYBBP1A, SRPK2, RHOT2, SRP68, PUM1, SLC25A3, SRPK1, RPL19, BEND3, SEC61A1, LSG1, NOC3L, TNKS1BP1, GTF3C3, TUBGCP3, PRPF40A, TRMT10C, URGCP, XRN2, MSH3, XRCC1, GEMIN4, DIS3L2, BCLAF1, SBF2, DHTKD1, ATXN2, ARID4B, TOR1AIP1, RPL29, NAA16, PRPF6, KIFAP3, TMEM33, WASF2, NACAD, LIG3, POLE, CKAP4, TCEB3, MTA1, GNA13, DHX38, PHF6, ELAVL4, DDX3X, CTR9, PRPF19, CAMSAP2, PRMT3, SH3PXD2B, SCAF8, MAGED1, ILF2, TONSL, PPP1R12A, SRSF5, KIAA0020, PTBP1, CAD, ACSL3, CHD1L, STAU1, MRPL38, DVL2, GNAI3, RPL10A, RPL6, MRPS5, CDK11B, MRPS34, PES1, ATP5C1, STXBP3, HNRNPLL, CHTF18, VPS39, SART3, COPA, PRPF3, UBE2O, ABCF2, HNRNPH3, EARS2, DHX40, ARHGEF7, EMC1, CASK, PTK2, SORT1, OGT, ATP12A, LMNB1, SLC4A7, PFKP, VDAC2, RBM25, ATL3, DHX36, TFIP11, EXOSC10, GTF3C1, SRSF1, PPP6C, TRAPPC9, RAD21, DNAJC13, ACOT1, ZC3H4, SRRM1, NDUFS3, DYRK1A, INTS1, SF3B2, EHHADH, MYO9B, ASCC2, WDR11, RPN1, EHD4, WDR91, SMARCAL1, NBAS, PI4KA, PAF1, EIF2B4, NUP107, EMC2, SYNE1, KLHL13, TBL1XR1, DNAJC10, SEC16A, METTL13, C7orf50, CDC42BPB, CLCN5, PGM3, DOCK7, ALYREF, POLR3A, TOP3A, WDR48, WDR81, DOCK1, CSNK2A2, CYC1, TLE3, THOC2, EIF2S3, MYO5A, SNX9, TARDBP, NAP1L4, CRKL, YTHDF2, PYGB, PABPC1, LTV1, PSMD4, KTN1, UBTF, WDR6, FUBP3, UBXN7, PHB, PDXP, CNOT3, TBL2, LLGL1, PLOD1, AHSA1, AAAS, ERGIC1, LARP4B, CYFIP1, DNM1, TARS2, ACSL1, ATXN1L, WDR59, SUCLA2, MLH1, CSNK2B, SYNCRIP, WDR36, FAM91A1, MTDH, UBE3C, CAPN1, BRIX1, DNAJB11, EDEM3, PLOD3, CLASP1, DPYSL3, MED16, NONO, EPM2AIP1, NT5DC2, ADRBK2, RPTOR, TELO2, MRPL37, PRKACB, ELMO1, TRAPPC8, ANAPC1, NIPSNAP1, EWSR1, PIK3R4, POLD1, IQGAP1, PRRC2A, COG1, ANKRD44, TFRC, DIEXF, FHOD1, SERPINH1, SPATA5, MED1, ABCF3, ZSWIM8, LMNA, HAT1, PABPC4, SMC4, HADH, RNGTT, TUBGCP2, ZNF598, SKIV2L2, GNB2L1, LARP1, DIP2B, BCR, IDH3B, LSM14A, FBL, NDUFS1, APPL2, USP39, SMC2, HCFC1, LANCL1, POLR2B, UPF2, CCBL2, MRPL15, MAGED2, AGK, GNPAT, AIMP1, GTF3C4, KDM1A, SCAMP3, RDH11, SRGAP2, CRNKL1, RFC5, PFKL, SPTBN1, PHOX2A, VDAC3, HNRNPA1, WDR26, DNM2, HAUS5, LCMT2, MCM7, CLINT1, UGDH, ACO1, TRIM46, PHKB, USP10, PCF11, YTHDF3, AARS2, FIGNL1, SFPQ, ATP5A1, NUP133, CPSF3, ANKRD28, PNN, C9orf64, ABCF1, ATL1, NAP1L1, HSPA9, MCCC2, FKBP5, CNOT1, TAF6, NEMF, UHRF1, SDHA, PELP1, HADHB, OAT, NEK9, AP3M1, PRKCA, LPCAT1, MRPL39, AFG3L2, WASF1, HNRNPL, RALGAPB, HK1, GBA, PLD3, CPSF7, HADHA, PDE12, DCX, LIMA1, HNRNPA2B1, POLR2A, MYH9, ZNF207, DDX55, ELP3, EIF2B5, MICAL1, TTI1, NES, HSDL1, GPSM1, PPM1F, C4orf27, SRRM2, OSBPL9, STAT3, IRF2BPL, KLC2, P3H1, STAT5B, UQCRC1, PCK2, CCAR2, TBC1D5, SACM1L, QARS, XPO4, CHD4, KIF2A, TACC3, NCL, BTAF1, RARS2, NCKAP1, EIF3D, RPS3, YME1L1, EIF4A3, HAUS6, HNRNPDL, MON2, G3BP2, WDHD1, CSNK1A1, SDAD1, RPS25, LSM14B, AP1M1, CCDC47, HNRNPK, DNMT1, NUP85, CUL5, TANC1, STAT1, COG5, STOML2, CDC45, OSBPL11, CIC, ABCD2, ARFGEF1, TROVE2, GBF1, SRPRB, UBE3A, GTPBP1, SCCPDH, RPS4X, PRPF4, ACTL6A, CCAR1, KIAA1033, TRAPPC12, HNRNPA3, FASTKD5, LYN, VPS18, PGRMC2, NUP214, AIFM1, TSG101, PPP6R3, OCRL, GANAB, IARS, SARS2, ATP2A2, EXOC1, NCAPH, TTC27, GNE, SRC, MIOS, ZCCHC8, GOLGA2, CARM1, ABCC1, PRMT5, LEO1, LMNB2, USP8, DARS, GYS1, APEH, ZYG11B, AKAP1, ELAVL1, MCM5, LRWD1, PSMC1, MOGS, TRIM28, EXOC6, LUC7L3, ANKFY1, NSUN2, HDAC2, G3BP1, QRICH1, INTS3, UBR1, XAB2, DYNC1LI1, TUFM, GAA, EXOC8, DHX8, LIMCH1, CLTC, SRPR, RNH1, ABI2, AQR, PREP, PPM1E, COG2, SEPT9, IDH2, MFN2, EXOC4, VPS33B, INTS4, GNB1, MSH6, HNRNPC, ERLIN1, EPRS, LRRC49, RPAP1, MCM3, PSMC4, PSMD3, GNL1, TRIP13, CUX1, PFAS, MAP1S, LRCH1, MRPL19, ABCD1, EIF3F, PDS5B, SMC3, KIF4A, FANCD2, IRF2BP1, SMC1A, RNF20, CLPX, NOC2L, DLAT, CTBP1, APPL1, NAA35, VPS45, PUM2, RELA, NUP210, RANBP9, DNAJC9, WRN, PRKAA1, AIMP2, VPS8, MAD1L1, MRE11A, ATP13A1, ATG7, CEP131, TRIM33, SLC25A10, HERC4, LRRFIP1, POLR1C, IPO9, GEMIN5, METAP2, SMG8, WASL, PPP1CB, SCFD1, RANBP3, RB1, CLTA, RNF40, SNRNP70, NCSTN, MGEA5, NARS, EIF4E, INPP4A, TFB2M, SEL1L, ARGLU1, PPP4R1, ANKRD17, TTK, RAD50, KIF2C, GOLGA3, TRAPPC11, GIGYF2, MSI2, CYFIP2, CDK5, HBS1L, IFT81, UFL1, PFKM, SMARCAD1, WDR35, PRIM2, NAMPT, PSMD2, MSH2, SOGA3, HEATR6, SFXN1, ARCN1, OGDH, FDPS, PSMC5, INSR, IRF2BP2, DDOST, ATXN2L, CSNK2A1, EIF2S2, MAP4, LTN1, COPB1, BRAT1, SMC6, SNRPN, RIC8A, SKIV2L, EIF4A1, KIF15, CLPTM1L, KPNA1, VPS16, VPS26B, RNPEP, RBM39, PMS1, FAM129B, RFC3, NUP155, RBM26, KIF21A, GAPVD1, C2CD5, WAPAL, RPS13, ARHGEF1, ACTR1A, KLC4, ISLR2, DCK, LRRC8A, STT3A, BOP1, RPN2, AFTPH, ORC3, FOXK1, CD2BP2, PDHA1, PPP6R1, PANK4, KIAA0196, WDR77, CHUK, DDX1, COLGALT1, VAPA, PPME1, CAMSAP1, RABL6, RTCB, SRRT, PIK3C3, NUMA1, STXBP1, OTUB1, UBAP2L, EXOC5, LRRC59, EXOC3, RQCD1, FLII, COPG2, USP5, XPOT, TIMM44, ATP1A1, SBF1, ARPC1B, PLK1, OSBPL8, BAG6, PPP6R2, FAM98B, VPS52, FADS2, EIF4G2, EIF4G3, HSPA8, POLR1B, PSMC6, SFSWAP, VPS33A, MCM10, AVL9, RINT1, PPIB, FBXL18, MFAP1, KIF13B, ATP2C1, ERCC2, CTTNBP2NL, WDR82, VARS, KPNA6, MIA3, HEATR1, SEC23B, AASDHPPT, POLR3B, ALDH18A1, PIKFYVE, MPP6, MRI1, CAPN7, RAB3GAP2, NCAPD2, UGGT1, IKBKAP, KDM3B, CLNS1A, FEN1, ECH1, AP2B1, HNRNPH1, RARS, AGPS, FANCI, PYCR2, EHD1, BUB3, KIF5B, SYMPK, PC, ACAA2, NDC80, PRRC2C, MTHFD1L, FASN, RANBP6, VPS11, NUP93, STRN, SCYL1, DDX19A, GTF2I, SEC23A, CTNNB1, STAM, VPRBP, VCL, PDHB, SEC24D, ERCC4, GRN, ACADM, HSPA6, ERCC6L, RPL5, ARHGAP17, DDX6, MAPK8IP3, TJP1, RIOK1, ERP29, PARG, NUP205, PALLD, COG4, TPP2, EPB41, VAC14, FUS, ZW10, KIF11, GET4, MCM6, EIF2S1, CSDE1, DHX16, GFM1, RABGAP1, TTC28, XPO1, EXOC2, DCTN1, ACBD3, RFC4, PARP1, COPG1, GPRIN1, EIF3C, CUL1, C14orf166, RTL1, STRIP1, MRPS2, PPP2R5D, EIF4G1, EXOSC4, MCM4, SEC63, WDR1, CUL4B, CRMP1, NSF, RNMT, BLVRA, UBE4A, PCBP1, MLLT4, RNF214, ARVCF, CKAP5, NUP188, SMCR8, CTNNA1, SYT1, PCM1, KNTC1, GFPT1, THYN1, SARM1, LPIN1, TIA1, NUP54, PKN1, SUMO4, DICER1, KIF3A, IPO8, CLIC4, PSMD14, GLG1, ABCE1, SMEK1, NCAPG, PPP5C, RTF1, IARS2, PDS5A, PHGDH, RPS6KA3, LONP1, ROCK1, CDK6, LARS, KPNA3, HNRNPAB, MCM2, PPP2R2A, HSP90AB2P, VCPIP1, PCBP2, RPA1, SEC24A, HECTD3, RCC2, DIS3, SMS, KHSRP, CLGN, GNAS, FOCAD, SEC23IP, ACOT7, HK2, CCDC6, MFN1, WDR7, CNN3, KIAA1524, RAB3GAP1, OXCT1, SBNO1, PRPSAP2, ACTR3, CTPS2, TMEM43, FAM21A, LRRC47, VAPB, SCYL2, STRN4, NAE1, SREK1, TFG, SF3A1, CDK2, GPKOW, GPHN, PDCD4, U2AF2, UNC45A, VPS35, NAA15, ASNS, TOP2B, ACO2, AGAP3, ROCK2, NUDT21, NPEPPS, ADD1, AP1G1, CPSF6, DNAJC2, RPS5, CTPS1, IDH1, SEC24C, KIF3B, ACTR2, CPD, EEF1D, SAMHD1, ETFB, DNM1L, LRPPRC, MCMBP, RBM12, OPA1, FARSB, UPF1, PCMT1, USO1, COG3, CLPTM1, TLK2, PRUNE, ASPSCR1, MARS, PYCR1, TCERG1, MED23, PITPNB, ARPC2, UBE4B, DBR1, ETFA, BICD1, KLC1, WDR70, PXDN, DPYSL4, USP7, CLUH, TBRG4, OGFR, SV2A, PDCD6IP, PDLIM5, PSMC2, TRAP1, DRG1, SMEK2, TCP1, TNPO2, CALD1, ARIH2, POR, FKBP3, DCTN2, NPM1, USP48, IPO13, NUP88, NNT, TAOK1, PPWD1, PSPC1, PABPN1, POLA1, MTR, BCCIP, RUVBL2, C16orf62, SORD, PPP2CA, STRN3, RUVBL1, PPP1CA, CACTIN, RPAP3, VPS51, TUBB3, PRKDC, HSPA5, CCDC132, MRPS27, RBBP4, CAPZA1, SLC4A1AP, THUMPD3, FAF1, CDK4, GSTO1, NCBP1, CAPZB, SNRPA, TXLNG, NELFE, MUT, DYNC1LI2, CTTN, DYNC1I2, TIMELESS, CBS, TTLL12, ESYT1, LAMB1, KARS, PPIL4, LRRC40, TXLNA, RAD23B, TBCE, ACAD9, THADA, GCN1L1, SLK, PNKP, ACLY, ATP6V0A1, VTA1, TXNDC5, OXSR1, ACACA, TNPO3, CCDC93, TIPRL, RAN, HOOK3, PSME4, YWHAQ, PPM1G, PSMC3, SCARB2, EXOC7, DFNA5, TRMT6, CPNE3, SLC3A2, G6PD, EIF2B1, SF3B1, EXOC6B, HGS, DYNC1H1, DNAJC7, CANX, TSR1, TTC37, DARS2, ZPR1, SERBP1, HSP90AB1, TBCB, UCHL5, IMPDH2, PUF60, RANGAP1, PDXDC1, YWHAH, LARS2, ZC3H15, GMPS, YWHAG, SUPV3L1, SPAG9, IMPDH1, HSD17B10, GTF2F1, EXOSC9, CUL3, ARHGAP35, TUBB4B, EIF5B, KIF5C, PDIA6, LDHA, ATL2, SNX1, SF3B3, SRM, MAP2, DIAPH1, DBH, NHLRC2, ELP2, GRPEL1, TWF1, WBP11, ERP44, SERPINB6, VCP, HSPH1, CMTR1, KIF1A, USP47, EML4, PRMT1, ATP6V1B2, GPS1, CAND1, CLPB, PCNA, RPLP0, CORO7, TUBB, ANXA2, API5, SUPT16H, RUFY1, KIAA1279, PDIA3, ACTA1, SF3A3, DCTN4, CUL2, WARS, PGM2, NELFB, XPO5, UGP2, HSP90B1, GSR, SHMT2, IPO11, EIF3E, RDX, DNAJB1, KIAA1598, AARS, EFTUD1, HEATR5B, ENAH, TNPO1, LIG1, NRD1, DLD, STRA6, PAFAH1B1, NT5C2, SSRP1, NTRK3, HDGFRP2, EIF3G, CSE1L, ACAT1, TBCD, NAA10, MTHFD1, RALA, EIF3A, PRPS1, ISOC1, IPO7, HNRNPD, GAPDH, U2AF1, SUPT5H, PSMD8, RPS6KA1, NUF2, GDAP1, VPS26A, TUBB2B, CDH2, TMOD1, CBR1, HDLBP, CS, HSPD1, LMAN1, EIF3B, DDB1, PSMD1, DPYSL2, STRAP, RTN4, FLNA, AHCY, HSD17B4, GOLIM4, SPTAN1, IPO4, PKM, EIF3I, SF1, BZW2, XPO7, ACADVL, STAG2, DPP9, RECQL, GDI1, GARS, MMS19, EIF2A, IPO5, TCOF1, RAB5C, SAP30BP, VDAC1, TUBA1A, SEPT2, DBNL, PLAA, TOMM70A, NOMO1, ISYNA1, CTNNA2, EEF1B2, PAK4, NELFCD, GSPT1, KPNB1, MAP1A, COPS4, YWHAZ, KPNA2, EIF4B, PLS3, COPS3, HSPBP1, AP1B1, NASP, DDX39A, LUC7L2, APMAP, SEC31A, SRSF2, TXNRD1, ATP1A3, RRM2, COG7, FSD1, PRDX4, DCPS, NCAM1, NUDCD1, NAA25, RPL9, NPLOC4, YWHAB, ATP1B1, LSS, DNAAF5, METTL16, COPS6, XPNPEP1, ELAC2, PUS7, CCT3, SFN, AGL, PAPOLA, SRSF11, ALDH2, PSME2, CKMT1B, LDHB, PSMA7, RAB11A, PPP2R1A, GNAO1, LUC7L, COPS5, IMPA1, RRM1, PPID, DPP3, KIAA0368, SLC1A5, YARS, NUP50, TPM4, ITGB1, SARS, SEZ6L2, GTF2F2, GART, ALDOC, PSMD11, EIF6, DFFA, RAP1GDS1, NELFA, CARS, CCT4, P4HB, FSCN1, PSMD13, PSMA5, CCT5, PAPSS1, OSBP, SAE1, ATP6V1A, LMAN2, YWHAE, SRP54, IDE, SNX2, RPSA, BZW1, SND1, UBQLN1, MAPK1, CALR, MARCKSL1, SUGT1, TBC1D4, GLRX3, LETM1, HMGB1, EIF3H, SLC9A3R1, DDX42, LAP3, PRKCSH, EEF2, PSMD6, BCAP31, ANXA11, ACTN1, CCT6A, PSMA4, ANXA5, CCT7, EIF3L, FUBP1, SSB, PGM1, MAPRE1, UBA2, AMPD2, PPAT, CLIC1, CCT2, ECHS1, LTA4H, USP14, CCT8, ANK2, PDIA4, TPR, NRCAM, MAT2A, HTATSF1, THOP1, RANBP1, RSRC2, NMT1, AK2, EEF1G, TPM3, PSMA3, EIF4H, GLUD1, CAP1, TKT, ATP5B, TXNL1, STIP1, HMGB2, GGH, HSPB1, CALU, RPL17, PSMA1, RSRC1, ST13, PRDX6, EIF3J, PNPT1, APEX1, TARS, MARCKS, PSMA6, EEF1A1, COPB2, NUDT5, HSPA1A, ERO1L, ME2, RPH3A, ESD, EIF5, ADSL, RUFY3, DPYSL5, ANXA6, NUDC, NANS, GOT2, GLDC, PSAT1, SET, PAK2, UBA6, UCHL1, L1CAM, PGLS, MAP1B, CCDC124, EIF3M, VAT1, PAFAH1B3, ALDOA, IRGQ, UBQLN2, NACA, OLA1, ACTN4, ARHGDIA, PSMD7, CACYBP, PSMA2, CPNE1, MDH2, PGAM1, DDX46, ACAT2, ALCAM, HARS, CKB, FKBP4, ASNA1, GPI, INA, HYOU1, CHGA, MDH1, EZR, ANP32A, UBA1, ARG1, ANP32B, PAICS, ATIC, TPI1, PPA1, TALDO1, PGK1, DDX39B, TLN1, AKR1B1, ENO1, NGFR, TPTE, GGA1, GGA2, GGA3, USP36, NDFIP1, SOCS2, CDK12, EPHB4, NDUFA4L2, AKT1, SLC5A5, DOT1L, AKT2, SHC4, TRAF4, PTPN6, ERBB2, EGR1, HIPK2, POU4F2,
TPM3	KXD1, TFPT, MCC, EIF4A2, TPM3, TP73, NEK2, RAD21, ELAVL1, SP1, CUL3, CDK2, LRRK2, TPM4, SEC23IP, KYNU, TPM2, TPM1, PRDX1, THOC1, CDC123, SF3A2, SEPT9, HSPB1, BRCA1, MDC1, PAXIP1, HSP90AA1, HSP90AB1, FN1, PAN2, HDAC8, FBXO5, TRAP1, PARK2, FASN, FKBP4, FKBP5, MAGED2, CAP1, MCM3, MGEA5, TP53, HSF2, IFIT3, KCNE1, KIFC3, MAGEA11, PBX3, TRIM27, VPS52, TNNT1, TRIP6, MAD1L1, TLK1, OIP5, BLOC1S6, CCHCR1, THAP1, CCDC146, CCDC102B, CCDC114, SYCE1, IKBIP, C1orf216, LCA5L, FAM9C, HDDC3, WASH3P, LURAP1, SHMT2, MOV10, NXF1, CUL7, OBSL1, RNF2, EGFR, DAPK1, ACTN2, AHCYL1, ATP1A1, CKB, CKMT1B, CKMT1A, COX5A, CYC1, OSTF1, ACTN1, ACTN4, ATP5F1, COX4I1, MTCH1, MYH7B, NDUFB10, PSMA2, PSMA6, STMN1, TBCD, UQCRC2, NTRK1, DVL2, HOOK2, ADD1, CAPZA2, MYH9, PPP1CB, PPP1CC, IQGAP1, PDLIM7, ANLN, MYO5C, MYO19, MYO18A, Actb, Itga5, Myh9, Tpm1, Mis12, Calml3, Myh10, Tpm4, MCM2, RNF20, IMP3, CALCOCO1, JUN, METTL2B, CCDC101, SPAG9, PARK7, PDHA1, VDAC1, TMPO, CTNNB1, LARS, APOE, HDAC4, RXRA, EFTUD2, AAR2, PIH1D1, RPTOR, TNF, FGF11, NOD2, RNF181, AGR2, GPC1, KDM6B, MYC, CDK9, Prkaa1, Prkab1, METTL14, WTAP, ESR2, TET2, DISC1, NR2C2, CSK, AGRN, HOOK3, BMH1, BMH2, VMP1, SNRNP70, BIRC3, ATXN1, TAB2, PSMC5, HSF4, TSKS, NUP54, SNAPIN, TNNI1, PRKCDBP, FGA, PHLDB3, WASH1, THAP7, PLEKHA4, RAD18, PRKD1, SRC, HIST2H2BE, GFM1, MN1, ESR1, MAST2, UNK, DUX4, CIT, AURKB, CHRM3, ECT2, KIF14, KIF20A, SMARCA2, ARHGAP11A, SYDE2, ARHGAP39, Ophn1, MFN2, OPA1, UCHL1, Apc2, FBP1, DTNA, INSIG1, INSIG2, RIN3, TRIM24, PDIA4, SUMO2, MARCKS, CALM1, NEDD4, TKT, CALR, SOD1, FKBP3, TRIM33, RBM8A, PEBP1, PGAM1, CEP78, PTMS, DDX58, CD274, AR, ISG15, UFL1, TMOD1, TRIM37, HTRA4, NAA40, CCDC102A, CCDC6, EXOC4, RBMXL1, TSSC4, KIF5B, EAPP, TPM3P9, PTRF, ZFC3H1, CROCC, NDE1, CCDC96, JUND, ECD, PHF21A, NUF2, NDEL1, HSF1, HOMER2, PRPF8, RCOR1, KDM1A, HOMER1, RCOR3, NES, JUNB, BTF3, TRIM26, FBXW7, DPP4, E, nsp7, ORF7b, ORF8, S, FURIN, nsp4, nsp6, ORF10, CCNF, ANTXR1, FOS, GATA4, KLF10, KLF3, KLF9, ZIC3, NKX2-5, STAT5B,

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
TPM3
NTRK1

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Tgene	NTRK1	chr1:154142875	chr1:156845871	ENST00000368196		10	16	469_490	494.3333333333333	791.0	SQSTM1
Tgene	NTRK1	chr1:154142875	chr1:156845871	ENST00000524377		11	17	469_490	500.3333333333333	797.0	SQSTM1

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Related Drugs to TPM3-NTRK1

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to TPM3-NTRK1

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene	Tgene	Disease	Source	PMID
TPM3	NTRK1	Sarcoma	MyCancerGenome
TPM3	NTRK1	Nos	MyCancerGenome
TPM3	NTRK1	Breast Invasive Ductal Carcinoma	MyCancerGenome
TPM3	NTRK1	Colon Adenocarcinoma	MyCancerGenome
TPM3	NTRK1	Thyroid Gland Papillary Carcinoma	MyCancerGenome
TPM3	NTRK1	Colorectal Neuroendocrine Carcinoma	MyCancerGenome

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	TPM3	C1836448	Nemaline myopathy 1	9	CTD_human;GENOMICS_ENGLAND;UNIPROT
Hgene	TPM3	C0546264	Congenital Fiber Type Disproportion	4	CTD_human;GENOMICS_ENGLAND;UNIPROT
Hgene	TPM3	C0007097	Carcinoma	2	CTD_human
Hgene	TPM3	C0024667	Animal Mammary Neoplasms	2	CTD_human
Hgene	TPM3	C0024668	Mammary Neoplasms, Experimental	2	CTD_human
Hgene	TPM3	C0205696	Anaplastic carcinoma	2	CTD_human
Hgene	TPM3	C0205697	Carcinoma, Spindle-Cell	2	CTD_human
Hgene	TPM3	C0205698	Undifferentiated carcinoma	2	CTD_human
Hgene	TPM3	C0205699	Carcinomatosis	2	CTD_human
Hgene	TPM3	C0206157	Myopathies, Nemaline	2	GENOMICS_ENGLAND
Hgene	TPM3	C1257925	Mammary Carcinoma, Animal	2	CTD_human
Hgene	TPM3	C0001418	Adenocarcinoma	1	CTD_human
Hgene	TPM3	C0007102	Malignant tumor of colon	1	CTD_human
Hgene	TPM3	C0009375	Colonic Neoplasms	1	CTD_human
Hgene	TPM3	C0023893	Liver Cirrhosis, Experimental	1	CTD_human
Hgene	TPM3	C0024623	Malignant neoplasm of stomach	1	CTD_human
Hgene	TPM3	C0038356	Stomach Neoplasms	1	CTD_human
Hgene	TPM3	C0040136	Thyroid Neoplasm	1	CTD_human
Hgene	TPM3	C0151468	Thyroid Gland Follicular Adenoma	1	CTD_human
Hgene	TPM3	C0205641	Adenocarcinoma, Basal Cell	1	CTD_human
Hgene	TPM3	C0205642	Adenocarcinoma, Oxyphilic	1	CTD_human
Hgene	TPM3	C0205643	Carcinoma, Cribriform	1	CTD_human
Hgene	TPM3	C0205644	Carcinoma, Granular Cell	1	CTD_human
Hgene	TPM3	C0205645	Adenocarcinoma, Tubular	1	CTD_human
Hgene	TPM3	C0270960	Congenital myopathy (disorder)	1	GENOMICS_ENGLAND
Hgene	TPM3	C0334121	Inflammatory Myofibroblastic Tumor	1	ORPHANET
Hgene	TPM3	C0546125	Nemaline Myopathy, Childhood Onset	1	ORPHANET
Hgene	TPM3	C0549473	Thyroid carcinoma	1	CTD_human
Hgene	TPM3	C1708349	Hereditary Diffuse Gastric Cancer	1	CTD_human
Hgene	TPM3	C3710589	Cap Myopathy	1	ORPHANET
Tgene	NTRK1	C0020074	HSAN Type IV	17	CTD_human;GENOMICS_ENGLAND;UNIPROT
Tgene	NTRK1	C0238463	Papillary thyroid carcinoma	3	ORPHANET
Tgene	NTRK1	C0002768	Congenital Pain Insensitivity	1	ORPHANET
Tgene	NTRK1	C0005586	Bipolar Disorder	1	CTD_human
Tgene	NTRK1	C0005587	Depression, Bipolar	1	CTD_human
Tgene	NTRK1	C0017638	Glioma	1	CTD_human
Tgene	NTRK1	C0020075	Hereditary Sensory Autonomic Neuropathy, Type 5	1	CTD_human;ORPHANET
Tgene	NTRK1	C0024713	Manic Disorder	1	CTD_human
Tgene	NTRK1	C0027796	Neuralgia	1	CTD_human
Tgene	NTRK1	C0027819	Neuroblastoma	1	CTD_human
Tgene	NTRK1	C0033958	Psychosis, Brief Reactive	1	CTD_human
Tgene	NTRK1	C0033975	Psychotic Disorders	1	CTD_human
Tgene	NTRK1	C0036337	Schizoaffective Disorder	1	CTD_human
Tgene	NTRK1	C0036341	Schizophrenia	1	CTD_human
Tgene	NTRK1	C0036358	Schizophreniform Disorders	1	CTD_human
Tgene	NTRK1	C0038870	Neuralgia, Supraorbital	1	CTD_human
Tgene	NTRK1	C0042656	Neuralgia, Vidian	1	CTD_human
Tgene	NTRK1	C0234247	Neuralgia, Atypical	1	CTD_human
Tgene	NTRK1	C0234249	Neuralgia, Stump	1	CTD_human
Tgene	NTRK1	C0259783	mixed gliomas	1	CTD_human
Tgene	NTRK1	C0273115	Lung Injury	1	CTD_human
Tgene	NTRK1	C0338831	Manic	1	CTD_human
Tgene	NTRK1	C0423711	Neuralgia, Perineal	1	CTD_human
Tgene	NTRK1	C0423712	Neuralgia, Iliohypogastric Nerve	1	CTD_human
Tgene	NTRK1	C0555198	Malignant Glioma	1	CTD_human
Tgene	NTRK1	C0598589	Inherited neuropathies	1	GENOMICS_ENGLAND
Tgene	NTRK1	C0751371	Neuralgia, Ilioinguinal	1	CTD_human
Tgene	NTRK1	C0751372	Nerve Pain	1	CTD_human
Tgene	NTRK1	C0751373	Paroxysmal Nerve Pain	1	CTD_human
Tgene	NTRK1	C0752347	Lewy Body Disease	1	CTD_human
Tgene	NTRK1	C1833921	Familial medullary thyroid carcinoma	1	CTD_human;GENOMICS_ENGLAND;ORPHANET
Tgene	NTRK1	C2350344	Chronic Lung Injury	1	CTD_human