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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:TRAF2-CACNA1B

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: TRAF2-CACNA1B
FusionPDB ID: 93643
FusionGDB2.0 ID: 93643
HgeneTgene
Gene symbol

TRAF2

CACNA1B

Gene ID

10010

774

Gene nameTRAF family member associated NFKB activatorcalcium voltage-gated channel subunit alpha1 B
SynonymsI-TRAF|ITRAF|TRAF2BIII|CACNL1A5|CACNN|Cav2.2|DYT23|NEDNEH
Cytomap

2q24.2

9q34.3

Type of geneprotein-codingprotein-coding
DescriptionTRAF family member-associated NF-kappa-B activatorTRAF-interacting proteinvoltage-dependent N-type calcium channel subunit alpha-1BCav2.2 voltage-gated Ca2+ channelbrain calcium channel IIIcalcium channel alpha12.2 subunitcalcium channel, L type, alpha-1 polypeptidecalcium channel, voltage-dependent, L type, alpha 1B subun
Modification date2020031320200313
UniProtAcc

TNIK

Q00975

Ensembl transtripts involved in fusion geneENST idsENST00000247668, ENST00000359662, 
ENST00000536468, ENST00000482854, 
ENST00000277550, ENST00000371365, 
ENST00000371367, ENST00000545473, 
ENST00000277549, ENST00000277551, 
ENST00000371355, ENST00000371357, 
ENST00000371363, ENST00000371372, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score7 X 6 X 6=2527 X 8 X 4=224
# samples 77
** MAII scorelog2(7/252*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/224*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: TRAF2 [Title/Abstract] AND CACNA1B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)TRAF2(139794972)-CACNA1B(140970271), # samples:1
TRAF2(139794972)-CACNA1B(140967940), # samples:1
Anticipated loss of major functional domain due to fusion event.TRAF2-CACNA1B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TRAF2-CACNA1B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TRAF2-CACNA1B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
TRAF2-CACNA1B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCACNA1B

GO:0050804

modulation of chemical synaptic transmission

23376566

TgeneCACNA1B

GO:1904645

response to amyloid-beta

23376566


check buttonFusion gene breakpoints across TRAF2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CACNA1B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-SY-A9G0-01ATRAF2chr9

139794972

-CACNA1Bchr9

140967940

+
ChimerDB4BLCATCGA-SY-A9G0-01ATRAF2chr9

139794972

+CACNA1Bchr9

140970271

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000536468TRAF2chr9139794972+ENST00000277551CACNA1Bchr9140970271+26955391492395748
ENST00000536468TRAF2chr9139794972+ENST00000371372CACNA1Bchr9140970271+53275391492701850
ENST00000536468TRAF2chr9139794972+ENST00000277549CACNA1Bchr9140970271+53275391492701850
ENST00000536468TRAF2chr9139794972+ENST00000371363CACNA1Bchr9140970271+53275391492701850
ENST00000536468TRAF2chr9139794972+ENST00000371355CACNA1Bchr9140970271+53275391492701850
ENST00000536468TRAF2chr9139794972+ENST00000371357CACNA1Bchr9140970271+53275391492701850
ENST00000247668TRAF2chr9139794972+ENST00000277551CACNA1Bchr9140970271+2574418282274748
ENST00000247668TRAF2chr9139794972+ENST00000371372CACNA1Bchr9140970271+5206418282580850
ENST00000247668TRAF2chr9139794972+ENST00000277549CACNA1Bchr9140970271+5206418282580850
ENST00000247668TRAF2chr9139794972+ENST00000371363CACNA1Bchr9140970271+5206418282580850
ENST00000247668TRAF2chr9139794972+ENST00000371355CACNA1Bchr9140970271+5206418282580850
ENST00000247668TRAF2chr9139794972+ENST00000371357CACNA1Bchr9140970271+5206418282580850
ENST00000359662TRAF2chr9139794972+ENST00000277551CACNA1Bchr9140970271+2624468212324767
ENST00000359662TRAF2chr9139794972+ENST00000371372CACNA1Bchr9140970271+5256468212630869
ENST00000359662TRAF2chr9139794972+ENST00000277549CACNA1Bchr9140970271+5256468212630869
ENST00000359662TRAF2chr9139794972+ENST00000371363CACNA1Bchr9140970271+5256468212630869
ENST00000359662TRAF2chr9139794972+ENST00000371355CACNA1Bchr9140970271+5256468212630869
ENST00000359662TRAF2chr9139794972+ENST00000371357CACNA1Bchr9140970271+5256468212630869
ENST00000536468TRAF2chr9139794972-ENST00000277551CACNA1Bchr9140967940+28785391492578809
ENST00000536468TRAF2chr9139794972-ENST00000371372CACNA1Bchr9140967940+55105391492884911
ENST00000536468TRAF2chr9139794972-ENST00000277549CACNA1Bchr9140967940+55105391492884911
ENST00000536468TRAF2chr9139794972-ENST00000371363CACNA1Bchr9140967940+55105391492884911
ENST00000536468TRAF2chr9139794972-ENST00000371355CACNA1Bchr9140967940+55105391492884911
ENST00000536468TRAF2chr9139794972-ENST00000371357CACNA1Bchr9140967940+55105391492884911
ENST00000247668TRAF2chr9139794972-ENST00000277551CACNA1Bchr9140967940+2757418282457809
ENST00000247668TRAF2chr9139794972-ENST00000371372CACNA1Bchr9140967940+5389418282763911
ENST00000247668TRAF2chr9139794972-ENST00000277549CACNA1Bchr9140967940+5389418282763911
ENST00000247668TRAF2chr9139794972-ENST00000371363CACNA1Bchr9140967940+5389418282763911
ENST00000247668TRAF2chr9139794972-ENST00000371355CACNA1Bchr9140967940+5389418282763911
ENST00000247668TRAF2chr9139794972-ENST00000371357CACNA1Bchr9140967940+5389418282763911
ENST00000359662TRAF2chr9139794972-ENST00000277551CACNA1Bchr9140967940+2807468212507828
ENST00000359662TRAF2chr9139794972-ENST00000371372CACNA1Bchr9140967940+5439468212813930
ENST00000359662TRAF2chr9139794972-ENST00000277549CACNA1Bchr9140967940+5439468212813930
ENST00000359662TRAF2chr9139794972-ENST00000371363CACNA1Bchr9140967940+5439468212813930
ENST00000359662TRAF2chr9139794972-ENST00000371355CACNA1Bchr9140967940+5439468212813930
ENST00000359662TRAF2chr9139794972-ENST00000371357CACNA1Bchr9140967940+5439468212813930

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000536468ENST00000277551TRAF2chr9139794972+CACNA1Bchr9140970271+0.066958250.93304175
ENST00000536468ENST00000371372TRAF2chr9139794972+CACNA1Bchr9140970271+0.008950220.99104977
ENST00000536468ENST00000277549TRAF2chr9139794972+CACNA1Bchr9140970271+0.008950220.99104977
ENST00000536468ENST00000371363TRAF2chr9139794972+CACNA1Bchr9140970271+0.008950220.99104977
ENST00000536468ENST00000371355TRAF2chr9139794972+CACNA1Bchr9140970271+0.008950220.99104977
ENST00000536468ENST00000371357TRAF2chr9139794972+CACNA1Bchr9140970271+0.008950220.99104977
ENST00000247668ENST00000277551TRAF2chr9139794972+CACNA1Bchr9140970271+0.063740060.9362599
ENST00000247668ENST00000371372TRAF2chr9139794972+CACNA1Bchr9140970271+0.0083153620.9916847
ENST00000247668ENST00000277549TRAF2chr9139794972+CACNA1Bchr9140970271+0.0083153620.9916847
ENST00000247668ENST00000371363TRAF2chr9139794972+CACNA1Bchr9140970271+0.0083153620.9916847
ENST00000247668ENST00000371355TRAF2chr9139794972+CACNA1Bchr9140970271+0.0083153620.9916847
ENST00000247668ENST00000371357TRAF2chr9139794972+CACNA1Bchr9140970271+0.0083153620.9916847
ENST00000359662ENST00000277551TRAF2chr9139794972+CACNA1Bchr9140970271+0.0478164440.9521836
ENST00000359662ENST00000371372TRAF2chr9139794972+CACNA1Bchr9140970271+0.0051951390.9948048
ENST00000359662ENST00000277549TRAF2chr9139794972+CACNA1Bchr9140970271+0.0051951390.9948048
ENST00000359662ENST00000371363TRAF2chr9139794972+CACNA1Bchr9140970271+0.0051951390.9948048
ENST00000359662ENST00000371355TRAF2chr9139794972+CACNA1Bchr9140970271+0.0051951390.9948048
ENST00000359662ENST00000371357TRAF2chr9139794972+CACNA1Bchr9140970271+0.0051951390.9948048
ENST00000536468ENST00000277551TRAF2chr9139794972-CACNA1Bchr9140967940+0.0451950360.95480496
ENST00000536468ENST00000371372TRAF2chr9139794972-CACNA1Bchr9140967940+0.0051293790.99487066
ENST00000536468ENST00000277549TRAF2chr9139794972-CACNA1Bchr9140967940+0.0051293790.99487066
ENST00000536468ENST00000371363TRAF2chr9139794972-CACNA1Bchr9140967940+0.0051293790.99487066
ENST00000536468ENST00000371355TRAF2chr9139794972-CACNA1Bchr9140967940+0.0051293790.99487066
ENST00000536468ENST00000371357TRAF2chr9139794972-CACNA1Bchr9140967940+0.0051293790.99487066
ENST00000247668ENST00000277551TRAF2chr9139794972-CACNA1Bchr9140967940+0.0432942660.9567057
ENST00000247668ENST00000371372TRAF2chr9139794972-CACNA1Bchr9140967940+0.0047670440.995233
ENST00000247668ENST00000277549TRAF2chr9139794972-CACNA1Bchr9140967940+0.0047670440.995233
ENST00000247668ENST00000371363TRAF2chr9139794972-CACNA1Bchr9140967940+0.0047670440.995233
ENST00000247668ENST00000371355TRAF2chr9139794972-CACNA1Bchr9140967940+0.0047670440.995233
ENST00000247668ENST00000371357TRAF2chr9139794972-CACNA1Bchr9140967940+0.0047670440.995233
ENST00000359662ENST00000277551TRAF2chr9139794972-CACNA1Bchr9140967940+0.0357055330.9642945
ENST00000359662ENST00000371372TRAF2chr9139794972-CACNA1Bchr9140967940+0.0039151880.9960848
ENST00000359662ENST00000277549TRAF2chr9139794972-CACNA1Bchr9140967940+0.0039151880.9960848
ENST00000359662ENST00000371363TRAF2chr9139794972-CACNA1Bchr9140967940+0.0039151880.9960848
ENST00000359662ENST00000371355TRAF2chr9139794972-CACNA1Bchr9140967940+0.0039151880.9960848
ENST00000359662ENST00000371357TRAF2chr9139794972-CACNA1Bchr9140967940+0.0039151880.9960848

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>93643_93643_1_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140967940_ENST00000277549_length(amino acids)=911AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH
PTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNAL
LQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARH

--------------------------------------------------------------

>93643_93643_2_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140967940_ENST00000277551_length(amino acids)=809AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH

--------------------------------------------------------------

>93643_93643_3_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140967940_ENST00000371355_length(amino acids)=911AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH
PTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNAL
LQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARH

--------------------------------------------------------------

>93643_93643_4_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140967940_ENST00000371357_length(amino acids)=911AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH
PTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNAL
LQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARH

--------------------------------------------------------------

>93643_93643_5_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140967940_ENST00000371363_length(amino acids)=911AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH
PTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNAL
LQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARH

--------------------------------------------------------------

>93643_93643_6_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140967940_ENST00000371372_length(amino acids)=911AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH
PTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNAL
LQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARH

--------------------------------------------------------------

>93643_93643_7_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140970271_ENST00000277549_length(amino acids)=850AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSS
PIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSS

--------------------------------------------------------------

>93643_93643_8_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140970271_ENST00000277551_length(amino acids)=748AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQAGSAVGFPNTTPCCRETPSASPWPLALELALTLTWGSVWTVRPLST

--------------------------------------------------------------

>93643_93643_9_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140970271_ENST00000371355_length(amino acids)=850AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSS
PIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSS

--------------------------------------------------------------

>93643_93643_10_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140970271_ENST00000371357_length(amino acids)=850AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSS
PIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSS

--------------------------------------------------------------

>93643_93643_11_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140970271_ENST00000371363_length(amino acids)=850AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSS
PIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSS

--------------------------------------------------------------

>93643_93643_12_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000247668_CACNA1B_chr9_140970271_ENST00000371372_length(amino acids)=850AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSS
PIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSS

--------------------------------------------------------------

>93643_93643_13_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140967940_ENST00000277549_length(amino acids)=930AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRNNFINLSFLRLFRAARLIKLLRQGYTIRILL
WTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATEC
GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPAR
VAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM
IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPH
EARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTP
DRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYS
CDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTS
LPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRR

--------------------------------------------------------------

>93643_93643_14_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140967940_ENST00000277551_length(amino acids)=828AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRNNFINLSFLRLFRAARLIKLLRQGYTIRILL
WTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATEC
GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPAR
VAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM
IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPH
EARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTP
DRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYS
CDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQAGSAVGFPNTTPCCRETPSASPWPLALELALTLTWGSVWTVRPLSTPCLRTLSLSR

--------------------------------------------------------------

>93643_93643_15_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140967940_ENST00000371355_length(amino acids)=930AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRNNFINLSFLRLFRAARLIKLLRQGYTIRILL
WTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATEC
GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPAR
VAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM
IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPH
EARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTP
DRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYS
CDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTS
LPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRR

--------------------------------------------------------------

>93643_93643_16_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140967940_ENST00000371357_length(amino acids)=930AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRNNFINLSFLRLFRAARLIKLLRQGYTIRILL
WTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATEC
GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPAR
VAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM
IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPH
EARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTP
DRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYS
CDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTS
LPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRR

--------------------------------------------------------------

>93643_93643_17_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140967940_ENST00000371363_length(amino acids)=930AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRNNFINLSFLRLFRAARLIKLLRQGYTIRILL
WTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATEC
GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPAR
VAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM
IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPH
EARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTP
DRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYS
CDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTS
LPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRR

--------------------------------------------------------------

>93643_93643_18_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140967940_ENST00000371372_length(amino acids)=930AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRNNFINLSFLRLFRAARLIKLLRQGYTIRILL
WTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATEC
GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPAR
VAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM
IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPH
EARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTP
DRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYS
CDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTS
LPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRR

--------------------------------------------------------------

>93643_93643_19_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140970271_ENST00000277549_length(amino acids)=869AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRVFGNIALDDDTSINRHNNFRTFLQALMLLFR
SATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWA
NLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQ
PVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQL
PQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTF

--------------------------------------------------------------

>93643_93643_20_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140970271_ENST00000277551_length(amino acids)=767AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRVFGNIALDDDTSINRHNNFRTFLQALMLLFR
SATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWA
NLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQ
PVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQAGSAVGFPNTTPCCRETPSASPWPLAL

--------------------------------------------------------------

>93643_93643_21_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140970271_ENST00000371355_length(amino acids)=869AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRVFGNIALDDDTSINRHNNFRTFLQALMLLFR
SATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWA
NLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQ
PVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQL
PQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTF

--------------------------------------------------------------

>93643_93643_22_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140970271_ENST00000371357_length(amino acids)=869AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRVFGNIALDDDTSINRHNNFRTFLQALMLLFR
SATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWA
NLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQ
PVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQL
PQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTF

--------------------------------------------------------------

>93643_93643_23_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140970271_ENST00000371363_length(amino acids)=869AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRVFGNIALDDDTSINRHNNFRTFLQALMLLFR
SATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWA
NLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQ
PVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQL
PQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTF

--------------------------------------------------------------

>93643_93643_24_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000359662_CACNA1B_chr9_140970271_ENST00000371372_length(amino acids)=869AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSVKMPACGMVTEAPAVGSRPRSPSSYDLVLHVPLTGAEACLMSVEEETELLLRVFGNIALDDDTSINRHNNFRTFLQALMLLFR
SATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWA
NLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQ
PVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQL
PQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTF

--------------------------------------------------------------

>93643_93643_25_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140967940_ENST00000277549_length(amino acids)=911AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH
PTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNAL
LQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARH

--------------------------------------------------------------

>93643_93643_26_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140967940_ENST00000277551_length(amino acids)=809AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH

--------------------------------------------------------------

>93643_93643_27_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140967940_ENST00000371355_length(amino acids)=911AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH
PTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNAL
LQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARH

--------------------------------------------------------------

>93643_93643_28_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140967940_ENST00000371357_length(amino acids)=911AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH
PTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNAL
LQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARH

--------------------------------------------------------------

>93643_93643_29_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140967940_ENST00000371363_length(amino acids)=911AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH
PTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNAL
LQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARH

--------------------------------------------------------------

>93643_93643_30_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140967940_ENST00000371372_length(amino acids)=911AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYENNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAM
LFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFL
MLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMT
VHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAP
GGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRS
GALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHR
RRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSH
PTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNAL
LQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARH

--------------------------------------------------------------

>93643_93643_31_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140970271_ENST00000277549_length(amino acids)=850AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSS
PIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSS

--------------------------------------------------------------

>93643_93643_32_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140970271_ENST00000277551_length(amino acids)=748AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQAGSAVGFPNTTPCCRETPSASPWPLALELALTLTWGSVWTVRPLST

--------------------------------------------------------------

>93643_93643_33_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140970271_ENST00000371355_length(amino acids)=850AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSS
PIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSS

--------------------------------------------------------------

>93643_93643_34_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140970271_ENST00000371357_length(amino acids)=850AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSS
PIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSS

--------------------------------------------------------------

>93643_93643_35_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140970271_ENST00000371363_length(amino acids)=850AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSS
PIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSS

--------------------------------------------------------------

>93643_93643_36_TRAF2-CACNA1B_TRAF2_chr9_139794972_ENST00000536468_CACNA1B_chr9_140970271_ENST00000371372_length(amino acids)=850AA_BP=1
MFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGI
SILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYEVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA
CDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPP
LGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEM
TVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSW
GTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRP
RGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSS
SSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSS
PIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSS

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Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:139794972/chr9:140970271)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
TRAF2

TNIK

CACNA1B

Q00975

1360FUNCTION: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are specifically blocked by omega-conotoxin-GVIA (AC P01522) (AC P01522) (By similarity). They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. {ECO:0000250|UniProtKB:Q02294}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRAF2chr9:139794972chr9:140967940ENST00000247668-41134_73122.0502.0Zinc fingerRING-type
HgeneTRAF2chr9:139794972chr9:140967940ENST00000536468-51234_73122.0502.0Zinc fingerRING-type
HgeneTRAF2chr9:139794972chr9:140970271ENST00000247668+41134_73122.0502.0Zinc fingerRING-type
HgeneTRAF2chr9:139794972chr9:140970271ENST00000536468+51234_73122.0502.0Zinc fingerRING-type
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471737_17481558.02340.0Calcium bindingOntology_term=ECO:0000255
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471737_17481619.02340.0Calcium bindingOntology_term=ECO:0000255
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231472050_20541558.02340.0Compositional biasNote=Poly-His
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231472118_21221558.02340.0Compositional biasNote=Poly-Ser
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233472050_20541619.02340.0Compositional biasNote=Poly-His
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233472118_21221619.02340.0Compositional biasNote=Poly-Ser
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471724_17591558.02340.0DomainEF-hand
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471724_17591619.02340.0DomainEF-hand
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471583_16011558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471622_16831558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471709_23391558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471622_16831619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471709_23391619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471564_15821558.02340.0TransmembraneHelical%3B Name%3DS4 of repeat IV
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471602_16211558.02340.0TransmembraneHelical%3B Name%3DS5 of repeat IV
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471684_17081558.02340.0TransmembraneHelical%3B Name%3DS6 of repeat IV
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471684_17081619.02340.0TransmembraneHelical%3B Name%3DS6 of repeat IV

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRAF2chr9:139794972chr9:140967940ENST00000247668-411299_348122.0502.0Coiled coilOntology_term=ECO:0000269
HgeneTRAF2chr9:139794972chr9:140967940ENST00000359662-111299_3480554.0Coiled coilOntology_term=ECO:0000269
HgeneTRAF2chr9:139794972chr9:140967940ENST00000536468-512299_348122.0502.0Coiled coilOntology_term=ECO:0000269
HgeneTRAF2chr9:139794972chr9:140970271ENST00000247668+411299_348122.0502.0Coiled coilOntology_term=ECO:0000269
HgeneTRAF2chr9:139794972chr9:140970271ENST00000359662+111299_3480554.0Coiled coilOntology_term=ECO:0000269
HgeneTRAF2chr9:139794972chr9:140970271ENST00000536468+512299_348122.0502.0Coiled coilOntology_term=ECO:0000269
HgeneTRAF2chr9:139794972chr9:140967940ENST00000247668-411351_496122.0502.0DomainMATH
HgeneTRAF2chr9:139794972chr9:140967940ENST00000359662-111351_4960554.0DomainMATH
HgeneTRAF2chr9:139794972chr9:140967940ENST00000536468-512351_496122.0502.0DomainMATH
HgeneTRAF2chr9:139794972chr9:140970271ENST00000247668+411351_496122.0502.0DomainMATH
HgeneTRAF2chr9:139794972chr9:140970271ENST00000359662+111351_4960554.0DomainMATH
HgeneTRAF2chr9:139794972chr9:140970271ENST00000536468+512351_496122.0502.0DomainMATH
HgeneTRAF2chr9:139794972chr9:140967940ENST00000247668-411124_180122.0502.0Zinc fingerTRAF-type 1
HgeneTRAF2chr9:139794972chr9:140967940ENST00000247668-411177_233122.0502.0Zinc fingerTRAF-type 2
HgeneTRAF2chr9:139794972chr9:140967940ENST00000359662-111124_1800554.0Zinc fingerTRAF-type 1
HgeneTRAF2chr9:139794972chr9:140967940ENST00000359662-111177_2330554.0Zinc fingerTRAF-type 2
HgeneTRAF2chr9:139794972chr9:140967940ENST00000359662-11134_730554.0Zinc fingerRING-type
HgeneTRAF2chr9:139794972chr9:140967940ENST00000536468-512124_180122.0502.0Zinc fingerTRAF-type 1
HgeneTRAF2chr9:139794972chr9:140967940ENST00000536468-512177_233122.0502.0Zinc fingerTRAF-type 2
HgeneTRAF2chr9:139794972chr9:140970271ENST00000247668+411124_180122.0502.0Zinc fingerTRAF-type 1
HgeneTRAF2chr9:139794972chr9:140970271ENST00000247668+411177_233122.0502.0Zinc fingerTRAF-type 2
HgeneTRAF2chr9:139794972chr9:140970271ENST00000359662+111124_1800554.0Zinc fingerTRAF-type 1
HgeneTRAF2chr9:139794972chr9:140970271ENST00000359662+111177_2330554.0Zinc fingerTRAF-type 2
HgeneTRAF2chr9:139794972chr9:140970271ENST00000359662+11134_730554.0Zinc fingerRING-type
HgeneTRAF2chr9:139794972chr9:140970271ENST00000536468+512124_180122.0502.0Zinc fingerTRAF-type 1
HgeneTRAF2chr9:139794972chr9:140970271ENST00000536468+512177_233122.0502.0Zinc fingerTRAF-type 2
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147451_4581558.02340.0Nucleotide bindingATP
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347451_4581619.02340.0Nucleotide bindingATP
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147379_3961558.02340.0RegionBinding to the beta subunit
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347379_3961619.02340.0RegionBinding to the beta subunit
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471137_14191558.02340.0RepeatNote=III
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471456_17111558.02340.0RepeatNote=IV
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147468_7121558.02340.0RepeatNote=II
TgeneCACNA1Bchr9:139794972chr9:140967940ENST00000371372314782_3591558.02340.0RepeatNote=I
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471137_14191619.02340.0RepeatNote=III
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471456_17111619.02340.0RepeatNote=IV
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347468_7121619.02340.0RepeatNote=II
TgeneCACNA1Bchr9:139794972chr9:140970271ENST00000371372334782_3591619.02340.0RepeatNote=I
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147115_1321558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471170_11851558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471206_12171558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471237_12461558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471266_12841558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471305_13911558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471417_14711558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471491_15051558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471526_15331558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147153_1631558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471553_15631558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147184_1871558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471_951558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147207_2251558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147246_3311558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147357_4821558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147502_5161558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147537_5441558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147563_5731558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147593_6111558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147632_6841558.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147710_11511558.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347115_1321619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471170_11851619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471206_12171619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471237_12461619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471266_12841619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471305_13911619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471417_14711619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471491_15051619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471526_15331619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347153_1631619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471553_15631619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471583_16011619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347184_1871619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471_951619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347207_2251619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347246_3311619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347357_4821619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347502_5161619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347537_5441619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347563_5731619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347593_6111619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347632_6841619.02340.0Topological domainExtracellular
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347710_11511619.02340.0Topological domainCytoplasmic
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471152_11691558.02340.0TransmembraneHelical%3B Name%3DS1 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471186_12051558.02340.0TransmembraneHelical%3B Name%3DS2 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471218_12361558.02340.0TransmembraneHelical%3B Name%3DS3 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471247_12651558.02340.0TransmembraneHelical%3B Name%3DS4 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471285_13041558.02340.0TransmembraneHelical%3B Name%3DS5 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147133_1521558.02340.0TransmembraneHelical%3B Name%3DS2 of repeat I
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471392_14161558.02340.0TransmembraneHelical%3B Name%3DS6 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471472_14901558.02340.0TransmembraneHelical%3B Name%3DS1 of repeat IV
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471506_15251558.02340.0TransmembraneHelical%3B Name%3DS2 of repeat IV
TgeneCACNA1Bchr9:139794972chr9:140967940ENST0000037137231471534_15521558.02340.0TransmembraneHelical%3B Name%3DS3 of repeat IV
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147164_1831558.02340.0TransmembraneHelical%3B Name%3DS3 of repeat I
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147188_2061558.02340.0TransmembraneHelical%3B Name%3DS4 of repeat I
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147226_2451558.02340.0TransmembraneHelical%3B Name%3DS5 of repeat I
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147332_3561558.02340.0TransmembraneHelical%3B Name%3DS6 of repeat I
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147483_5011558.02340.0TransmembraneHelical%3B Name%3DS1 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147517_5361558.02340.0TransmembraneHelical%3B Name%3DS2 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147545_5621558.02340.0TransmembraneHelical%3B Name%3DS3 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147574_5921558.02340.0TransmembraneHelical%3B Name%3DS4 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147612_6311558.02340.0TransmembraneHelical%3B Name%3DS5 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140967940ENST000003713723147685_7091558.02340.0TransmembraneHelical%3B Name%3DS6 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140967940ENST00000371372314796_1141558.02340.0TransmembraneHelical%3B Name%3DS1 of repeat I
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471152_11691619.02340.0TransmembraneHelical%3B Name%3DS1 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471186_12051619.02340.0TransmembraneHelical%3B Name%3DS2 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471218_12361619.02340.0TransmembraneHelical%3B Name%3DS3 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471247_12651619.02340.0TransmembraneHelical%3B Name%3DS4 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471285_13041619.02340.0TransmembraneHelical%3B Name%3DS5 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347133_1521619.02340.0TransmembraneHelical%3B Name%3DS2 of repeat I
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471392_14161619.02340.0TransmembraneHelical%3B Name%3DS6 of repeat III
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471472_14901619.02340.0TransmembraneHelical%3B Name%3DS1 of repeat IV
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471506_15251619.02340.0TransmembraneHelical%3B Name%3DS2 of repeat IV
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471534_15521619.02340.0TransmembraneHelical%3B Name%3DS3 of repeat IV
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471564_15821619.02340.0TransmembraneHelical%3B Name%3DS4 of repeat IV
TgeneCACNA1Bchr9:139794972chr9:140970271ENST0000037137233471602_16211619.02340.0TransmembraneHelical%3B Name%3DS5 of repeat IV
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347164_1831619.02340.0TransmembraneHelical%3B Name%3DS3 of repeat I
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347188_2061619.02340.0TransmembraneHelical%3B Name%3DS4 of repeat I
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347226_2451619.02340.0TransmembraneHelical%3B Name%3DS5 of repeat I
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347332_3561619.02340.0TransmembraneHelical%3B Name%3DS6 of repeat I
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347483_5011619.02340.0TransmembraneHelical%3B Name%3DS1 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347517_5361619.02340.0TransmembraneHelical%3B Name%3DS2 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347545_5621619.02340.0TransmembraneHelical%3B Name%3DS3 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347574_5921619.02340.0TransmembraneHelical%3B Name%3DS4 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347612_6311619.02340.0TransmembraneHelical%3B Name%3DS5 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140970271ENST000003713723347685_7091619.02340.0TransmembraneHelical%3B Name%3DS6 of repeat II
TgeneCACNA1Bchr9:139794972chr9:140970271ENST00000371372334796_1141619.02340.0TransmembraneHelical%3B Name%3DS1 of repeat I


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
TRAF2
CACNA1B


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to TRAF2-CACNA1B


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to TRAF2-CACNA1B


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource