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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein Structure
	pLDDT scores
	Ramachandran Plot of Fusion Protein Structure
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:UVRAG-ACER3

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: UVRAG-ACER3
	FusionPDB ID: 97779
	FusionGDB2.0 ID: 97779
		Hgene	Tgene
	Gene symbol	UVRAG	ACER3
	Gene ID	7405	55331
	Gene name	UV radiation resistance associated	alkaline ceramidase 3
	Synonyms	DHTX\|VPS38\|p63	APHC\|PHCA\|PLDECO
	Cytomap	11q13.5	11q13.5
	Type of gene	protein-coding	protein-coding
	Description	UV radiation resistance-associated gene proteinbeclin 1 binding proteindisrupted in heterotaxy	alkaline ceramidase 3alkCDase 3alkaline CDase 3alkaline dihydroceramidase SB89alkaline phytoceramidasephytoceramidase, alkaline
	Modification date	20200313	20200320
	UniProtAcc	.	Q9NUN7
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000356136, ENST00000528420, ENST00000531818, ENST00000532130, ENST00000533454, ENST00000539288, ENST00000525872, ENST00000538870,	ENST00000526597, ENST00000530182, ENST00000533873, ENST00000538157, ENST00000544113, ENST00000532485,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	41 X 18 X 15=11070	13 X 10 X 5=650
	# samples	49	15
	** MAII score	log2(49/11070*10)=-4.49772966266634 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(15/650*10)=-2.11547721741994 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: UVRAG [Title/Abstract] AND ACER3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	UVRAG(75728024)-ACER3(76726060), # samples:3 ACER3(76730820)-UVRAG(75826968), # samples:2
Anticipated loss of major functional domain due to fusion event.	ACER3-UVRAG seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ACER3-UVRAG seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. UVRAG-ACER3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. UVRAG-ACER3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. UVRAG-ACER3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. UVRAG-ACER3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	UVRAG	GO:0071900	regulation of protein serine/threonine kinase activity	22542840
Hgene	UVRAG	GO:0097352	autophagosome maturation	28306502
Hgene	UVRAG	GO:0097680	double-strand break repair via classical nonhomologous end joining	22542840
Tgene	ACER3	GO:0043067	regulation of programmed cell death	20068046
Tgene	ACER3	GO:0046512	sphingosine biosynthetic process	20068046
Tgene	ACER3	GO:0046514	ceramide catabolic process	30575723
Tgene	ACER3	GO:0071602	phytosphingosine biosynthetic process	11356846\|20068046

Fusion gene breakpoints across UVRAG (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ACER3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	SARC	TCGA-DX-AB2P-01A	UVRAG	chr11	75728024	+	ACER3	chr11	76726060	+
ChimerDB4	SARC	TCGA-LI-A9QH-01A	UVRAG	chr11	75728024	-	ACER3	chr11	76726060	+
ChimerDB4	SARC	TCGA-LI-A9QH-01A	UVRAG	chr11	75728024	+	ACER3	chr11	76726060	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000356136	UVRAG	chr11	75728024	+	ENST00000532485	ACER3	chr11	76726060	+	8244	1467	163	1773	536
ENST00000528420	UVRAG	chr11	75728024	+	ENST00000532485	ACER3	chr11	76726060	+	7985	1208	96	1514	472
ENST00000533454	UVRAG	chr11	75728024	+	ENST00000532485	ACER3	chr11	76726060	+	7639	862	4219	4752	177
ENST00000531818	UVRAG	chr11	75728024	+	ENST00000532485	ACER3	chr11	76726060	+	7817	1040	447	1346	299
ENST00000532130	UVRAG	chr11	75728024	+	ENST00000532485	ACER3	chr11	76726060	+	7364	587	48	893	281
ENST00000539288	UVRAG	chr11	75728024	+	ENST00000532485	ACER3	chr11	76726060	+	7431	654	4011	4544	177

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000356136	ENST00000532485	UVRAG	chr11	75728024	+	ACER3	chr11	76726060	+	0.00049123	0.99950874
ENST00000528420	ENST00000532485	UVRAG	chr11	75728024	+	ACER3	chr11	76726060	+	0.000679446	0.9993206
ENST00000533454	ENST00000532485	UVRAG	chr11	75728024	+	ACER3	chr11	76726060	+	0.013703251	0.9862968
ENST00000531818	ENST00000532485	UVRAG	chr11	75728024	+	ACER3	chr11	76726060	+	0.015209183	0.98479086
ENST00000532130	ENST00000532485	UVRAG	chr11	75728024	+	ACER3	chr11	76726060	+	0.013536955	0.986463
ENST00000539288	ENST00000532485	UVRAG	chr11	75728024	+	ACER3	chr11	76726060	+	0.013302654	0.9866974

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>97779_97779_1_UVRAG-ACER3_UVRAG_chr11_75728024_ENST00000356136_ACER3_chr11_76726060_ENST00000532485_length(amino acids)=536AA_BP=435
MVGGGKGAAADAGRVPAPPLGGPWIEMSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDT
YFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEII
FGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKI
LVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLN
EHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREVYPWLRGLGYTSLGI

--------------------------------------------------------------

>97779_97779_2_UVRAG-ACER3_UVRAG_chr11_75728024_ENST00000528420_ACER3_chr11_76726060_ENST00000532485_length(amino acids)=472AA_BP=371
MRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLL
IEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGK
EIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFL
KTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDN
INDKLTEKEREVYPWLRGLGYTSLGIFLLGFLFWNIDNIFCESLRNFRKKVPPIIGITTQFHAWWHILTGLGSYLHILFSLYTRTLYLRY

--------------------------------------------------------------

>97779_97779_3_UVRAG-ACER3_UVRAG_chr11_75728024_ENST00000531818_ACER3_chr11_76726060_ENST00000532485_length(amino acids)=299AA_BP=1
MEAVDWSYSYSAILEPPCLFFLKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECT
AKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGS
RSTIKDNINDKLTEKEREVYPWLRGLGYTSLGIFLLGFLFWNIDNIFCESLRNFRKKVPPIIGITTQFHAWWHILTGLGSYLHILFSLYT

--------------------------------------------------------------

>97779_97779_4_UVRAG-ACER3_UVRAG_chr11_75728024_ENST00000532130_ACER3_chr11_76726060_ENST00000532485_length(amino acids)=281AA_BP=180
MFLKKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCR
QLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKERE
VYPWLRGLGYTSLGIFLLGFLFWNIDNIFCESLRNFRKKVPPIIGITTQFHAWWHILTGLGSYLHILFSLYTRTLYLRYRPKVKFLFGIW

--------------------------------------------------------------

>97779_97779_5_UVRAG-ACER3_UVRAG_chr11_75728024_ENST00000533454_ACER3_chr11_76726060_ENST00000532485_length(amino acids)=177AA_BP=
MKIFKCLQKLSSVIIPANSELANALKASNNLRLSYESYENNYLLLNLSFSYQRHVYVTRNCFGPVVYDVLLDKHLCKTEYFKENHLQLEF

--------------------------------------------------------------

>97779_97779_6_UVRAG-ACER3_UVRAG_chr11_75728024_ENST00000539288_ACER3_chr11_76726060_ENST00000532485_length(amino acids)=177AA_BP=
MKIFKCLQKLSSVIIPANSELANALKASNNLRLSYESYENNYLLLNLSFSYQRHVYVTRNCFGPVVYDVLLDKHLCKTEYFKENHLQLEF

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:75728024/chr11:76726060)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	ACER3 Q9NUN7
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.	FUNCTION: Endoplasmic reticulum and Golgi ceramidase that catalyzes the hydrolysis of unsaturated long-chain C18:1-, C20:1- and C20:4-ceramides, dihydroceramides and phytoceramides into sphingoid bases like sphingosine and free fatty acids at alkaline pH (PubMed:20068046, PubMed:26792856, PubMed:20207939, PubMed:11356846, PubMed:30575723). Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (PubMed:20068046). Controls the generation of sphingosine in erythrocytes, and thereby sphingosine-1-phosphate in plasma (PubMed:20207939). Through the regulation of ceramides and sphingosine-1-phosphate homeostasis in the brain may play a role in neurons survival and function (By similarity). By regulating the levels of proinflammatory ceramides in immune cells and tissues, may modulate the inflammatory response (By similarity). {ECO:0000250\|UniProtKB:Q9D099, ECO:0000269\|PubMed:11356846, ECO:0000269\|PubMed:20068046, ECO:0000269\|PubMed:20207939, ECO:0000269\|PubMed:26792856, ECO:0000269\|PubMed:30575723, ECO:0000303\|PubMed:20068046}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

UVRAG

chr11:75728024

chr11:76726060

ENST00000356136

224_305

408.6666666666667

700.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

UVRAG

chr11:75728024

chr11:76726060

ENST00000356136

23_149

408.6666666666667

700.0

Domain

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

163_173

165.66666666666666

268.0

Topological domain

Lumenal

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

195_215

165.66666666666666

268.0

Topological domain

Cytoplasmic

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

237_267

165.66666666666666

268.0

Topological domain

Lumenal

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

109_118

32.666666666666664

135.0

Topological domain

Lumenal

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

140_141

32.666666666666664

135.0

Topological domain

Cytoplasmic

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

163_173

32.666666666666664

135.0

Topological domain

Lumenal

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

195_215

32.666666666666664

135.0

Topological domain

Cytoplasmic

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

237_267

32.666666666666664

135.0

Topological domain

Lumenal

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

56_61

32.666666666666664

135.0

Topological domain

Lumenal

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

83_87

32.666666666666664

135.0

Topological domain

Cytoplasmic

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

174_194

165.66666666666666

268.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

216_236

165.66666666666666

268.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

119_139

32.666666666666664

135.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

142_162

32.666666666666664

135.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

174_194

32.666666666666664

135.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

216_236

32.666666666666664

135.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

34_55

32.666666666666664

135.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

62_82

32.666666666666664

135.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

88_108

32.666666666666664

135.0

Transmembrane

Helical

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

109_118

165.66666666666666

268.0

Topological domain

Lumenal

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

140_141

165.66666666666666

268.0

Topological domain

Cytoplasmic

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

1_33

165.66666666666666

268.0

Topological domain

Cytoplasmic

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

56_61

165.66666666666666

268.0

Topological domain

Lumenal

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

83_87

165.66666666666666

268.0

Topological domain

Cytoplasmic

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000544113

1_33

32.666666666666664

135.0

Topological domain

Cytoplasmic

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

119_139

165.66666666666666

268.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

142_162

165.66666666666666

268.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

34_55

165.66666666666666

268.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

62_82

165.66666666666666

268.0

Transmembrane

Helical

Tgene

ACER3

chr11:75728024

chr11:76726060

ENST00000532485

88_108

165.66666666666666

268.0

Transmembrane

Helical

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Fusion Protein Structures

PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.

Fusion protein PDB link (fusion AA seq ID in FusionPDB)	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	AA seq	Len(AA seq)
PDB file >>>1145_UVRAG_75728024_ACER3_76726060_1145_UVRAG_75728024_ACER3_76726060_ranked_0.pdb	UVRAG	75728024	75728024	ENST00000532485	ACER3	chr11	76726060	+	MVGGGKGAAADAGRVPAPPLGGPWIEMSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDT YFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEII FGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKI LVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLN EHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREVYPWLRGLGYTSLGI	536

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pLDDT score distribution

pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

UVRAG_pLDDT.png

ACER3_pLDDT.png

pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

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Ramachandran Plot of Fusion Protein Structure

Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.

Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
UVRAG
ACER3

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs to UVRAG-ACER3

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to UVRAG-ACER3

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source