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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:VSIG1-MID2

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: VSIG1-MID2
FusionPDB ID: 98554
FusionGDB2.0 ID: 98554
HgeneTgene
Gene symbol

VSIG1

MID2

Gene ID

340547

11043

Gene nameV-set and immunoglobulin domain containing 1midline 2
Synonyms1700062D20Rik|GPA34|dJ889N15.1FXY2|MRX101|RNF60|TRIM1
Cytomap

Xq22.3

Xq22.3

Type of geneprotein-codingprotein-coding
DescriptionV-set and immunoglobulin domain-containing protein 1cell surface A33 antigenglycoprotein A34probable E3 ubiquitin-protein ligase MID2RING finger protein 60RING-type E3 ubiquitin transferase MID2midin 2midline defect 2tripartite motif protein 1tripartite motif-containing protein 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST idsENST00000217957, ENST00000415430, 
ENST00000485533, 		ENST00000262843, 
ENST00000443968, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score4 X 4 X 4=644 X 7 X 5=140
# samples 66
** MAII scorelog2(6/64*10)=-0.0931094043914815
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/140*10)=-1.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: VSIG1 [Title/Abstract] AND MID2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)VSIG1(107288409)-MID2(107169324), # samples:3
Anticipated loss of major functional domain due to fusion event.VSIG1-MID2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
VSIG1-MID2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
VSIG1-MID2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
VSIG1-MID2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
VSIG1-MID2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMID2

GO:0032897

negative regulation of viral transcription

18248090

TgeneMID2

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB signaling

23077300

TgeneMID2

GO:0045087

innate immune response

18248090

TgeneMID2

GO:0046597

negative regulation of viral entry into host cell

18248090

TgeneMID2

GO:1902187

negative regulation of viral release from host cell

18248090


check buttonFusion gene breakpoints across VSIG1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MID2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PAADTCGA-US-A77G-01AVSIG1chrX

107288409

-MID2chrX

107169324

+
ChimerDB4PAADTCGA-US-A77GVSIG1chrX

107288409

+MID2chrX

107169323

+
ChimerDB4PAADTCGA-US-A77GVSIG1chrX

107288409

+MID2chrX

107169324

+
ChimerDB4PRADTCGA-KK-A7B1-01AVSIG1chrX

107288409

-MID2chrX

107169324

+
ChimerDB4STADTCGA-VQ-A91K-01AVSIG1chrX

107301431

-MID2chrX

107159232

+
ChimerDB4STADTCGA-VQ-A91K-01AVSIG1chrX

107301431

+MID2chrX

107159232

+
ChimerDB4STADTCGA-VQ-A91KVSIG1chrX

107301431

+MID2chrX

107159231

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000415430VSIG1chrX107288409+ENST00000262843MID2chrX107169323+94121038820260
ENST00000415430VSIG1chrX107288409+ENST00000443968MID2chrX107169323+94121038820260
ENST00000217957VSIG1chrX107288409+ENST00000262843MID2chrX107169323+89716654776240
ENST00000217957VSIG1chrX107288409+ENST00000443968MID2chrX107169323+89716654776240
ENST00000415430VSIG1chrX107288409+ENST00000262843MID2chrX107169324+94121038820260
ENST00000415430VSIG1chrX107288409+ENST00000443968MID2chrX107169324+94121038820260
ENST00000217957VSIG1chrX107288409+ENST00000262843MID2chrX107169324+89716654776240
ENST00000217957VSIG1chrX107288409+ENST00000443968MID2chrX107169324+89716654776240

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000415430ENST00000262843VSIG1chrX107288409+MID2chrX107169323+0.0114883130.9885117
ENST00000415430ENST00000443968VSIG1chrX107288409+MID2chrX107169323+0.0114883130.9885117
ENST00000217957ENST00000262843VSIG1chrX107288409+MID2chrX107169323+0.0108416560.9891584
ENST00000217957ENST00000443968VSIG1chrX107288409+MID2chrX107169323+0.0108416560.9891584
ENST00000415430ENST00000262843VSIG1chrX107288409+MID2chrX107169324+0.0114883130.9885117
ENST00000415430ENST00000443968VSIG1chrX107288409+MID2chrX107169324+0.0114883130.9885117
ENST00000217957ENST00000262843VSIG1chrX107288409+MID2chrX107169324+0.0108416560.9891584
ENST00000217957ENST00000443968VSIG1chrX107288409+MID2chrX107169324+0.0108416560.9891584

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>98554_98554_1_VSIG1-MID2_VSIG1_chrX_107288409_ENST00000217957_MID2_chrX_107169323_ENST00000262843_length(amino acids)=240AA_BP=37
MRLSLVQASYWHLLLSTNLHTMVFAFWKVFLILSCLAGQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIF
IDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLH

--------------------------------------------------------------

>98554_98554_2_VSIG1-MID2_VSIG1_chrX_107288409_ENST00000217957_MID2_chrX_107169323_ENST00000443968_length(amino acids)=240AA_BP=37
MRLSLVQASYWHLLLSTNLHTMVFAFWKVFLILSCLAGQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIF
IDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLH

--------------------------------------------------------------

>98554_98554_3_VSIG1-MID2_VSIG1_chrX_107288409_ENST00000217957_MID2_chrX_107169324_ENST00000262843_length(amino acids)=240AA_BP=37
MRLSLVQASYWHLLLSTNLHTMVFAFWKVFLILSCLAGQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIF
IDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLH

--------------------------------------------------------------

>98554_98554_4_VSIG1-MID2_VSIG1_chrX_107288409_ENST00000217957_MID2_chrX_107169324_ENST00000443968_length(amino acids)=240AA_BP=37
MRLSLVQASYWHLLLSTNLHTMVFAFWKVFLILSCLAGQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIF
IDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLH

--------------------------------------------------------------

>98554_98554_5_VSIG1-MID2_VSIG1_chrX_107288409_ENST00000415430_MID2_chrX_107169323_ENST00000262843_length(amino acids)=260AA_BP=57
MLGDAQQISQANLGVIEEANLRLSLVQASYWHLLLSTNLHTMVFAFWKVFLILSCLAGQPFKLDPKMTHKKLKISNDGLQMEKDESSLKK
SHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLG

--------------------------------------------------------------

>98554_98554_6_VSIG1-MID2_VSIG1_chrX_107288409_ENST00000415430_MID2_chrX_107169323_ENST00000443968_length(amino acids)=260AA_BP=57
MLGDAQQISQANLGVIEEANLRLSLVQASYWHLLLSTNLHTMVFAFWKVFLILSCLAGQPFKLDPKMTHKKLKISNDGLQMEKDESSLKK
SHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLG

--------------------------------------------------------------

>98554_98554_7_VSIG1-MID2_VSIG1_chrX_107288409_ENST00000415430_MID2_chrX_107169324_ENST00000262843_length(amino acids)=260AA_BP=57
MLGDAQQISQANLGVIEEANLRLSLVQASYWHLLLSTNLHTMVFAFWKVFLILSCLAGQPFKLDPKMTHKKLKISNDGLQMEKDESSLKK
SHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLG

--------------------------------------------------------------

>98554_98554_8_VSIG1-MID2_VSIG1_chrX_107288409_ENST00000415430_MID2_chrX_107169324_ENST00000443968_length(amino acids)=260AA_BP=57
MLGDAQQISQANLGVIEEANLRLSLVQASYWHLLLSTNLHTMVFAFWKVFLILSCLAGQPFKLDPKMTHKKLKISNDGLQMEKDESSLKK
SHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLG

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:107288409/chrX:107169324)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMID2chrX:107288409chrX:107169323ENST00000443968710516_709502.3333333333333706.0DomainB30.2/SPRY
TgeneMID2chrX:107288409chrX:107169324ENST00000443968710516_709502.3333333333333706.0DomainB30.2/SPRY

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneVSIG1chrX:107288409chrX:107169323ENST00000217957+17140_22716.333333333333332388.0DomainNote=Ig-like C2-type
HgeneVSIG1chrX:107288409chrX:107169323ENST00000217957+1722_13216.333333333333332388.0DomainNote=Ig-like V-type
HgeneVSIG1chrX:107288409chrX:107169323ENST00000415430+18140_22716.333333333333332424.0DomainNote=Ig-like C2-type
HgeneVSIG1chrX:107288409chrX:107169323ENST00000415430+1822_13216.333333333333332424.0DomainNote=Ig-like V-type
HgeneVSIG1chrX:107288409chrX:107169324ENST00000217957+17140_22716.333333333333332388.0DomainNote=Ig-like C2-type
HgeneVSIG1chrX:107288409chrX:107169324ENST00000217957+1722_13216.333333333333332388.0DomainNote=Ig-like V-type
HgeneVSIG1chrX:107288409chrX:107169324ENST00000415430+18140_22716.333333333333332424.0DomainNote=Ig-like C2-type
HgeneVSIG1chrX:107288409chrX:107169324ENST00000415430+1822_13216.333333333333332424.0DomainNote=Ig-like V-type
HgeneVSIG1chrX:107288409chrX:107169323ENST00000217957+1722_23216.333333333333332388.0Topological domainExtracellular
HgeneVSIG1chrX:107288409chrX:107169323ENST00000217957+17254_38716.333333333333332388.0Topological domainCytoplasmic
HgeneVSIG1chrX:107288409chrX:107169323ENST00000415430+1822_23216.333333333333332424.0Topological domainExtracellular
HgeneVSIG1chrX:107288409chrX:107169323ENST00000415430+18254_38716.333333333333332424.0Topological domainCytoplasmic
HgeneVSIG1chrX:107288409chrX:107169324ENST00000217957+1722_23216.333333333333332388.0Topological domainExtracellular
HgeneVSIG1chrX:107288409chrX:107169324ENST00000217957+17254_38716.333333333333332388.0Topological domainCytoplasmic
HgeneVSIG1chrX:107288409chrX:107169324ENST00000415430+1822_23216.333333333333332424.0Topological domainExtracellular
HgeneVSIG1chrX:107288409chrX:107169324ENST00000415430+18254_38716.333333333333332424.0Topological domainCytoplasmic
HgeneVSIG1chrX:107288409chrX:107169323ENST00000217957+17233_25316.333333333333332388.0TransmembraneHelical
HgeneVSIG1chrX:107288409chrX:107169323ENST00000415430+18233_25316.333333333333332424.0TransmembraneHelical
HgeneVSIG1chrX:107288409chrX:107169324ENST00000217957+17233_25316.333333333333332388.0TransmembraneHelical
HgeneVSIG1chrX:107288409chrX:107169324ENST00000415430+18233_25316.333333333333332424.0TransmembraneHelical
TgeneMID2chrX:107288409chrX:107169323ENST00000262843710233_301532.3333333333334736.0Coiled coilOntology_term=ECO:0000255
TgeneMID2chrX:107288409chrX:107169323ENST00000443968710233_301502.3333333333333706.0Coiled coilOntology_term=ECO:0000255
TgeneMID2chrX:107288409chrX:107169324ENST00000262843710233_301532.3333333333334736.0Coiled coilOntology_term=ECO:0000255
TgeneMID2chrX:107288409chrX:107169324ENST00000443968710233_301502.3333333333333706.0Coiled coilOntology_term=ECO:0000255
TgeneMID2chrX:107288409chrX:107169323ENST00000262843710340_399532.3333333333334736.0DomainCOS
TgeneMID2chrX:107288409chrX:107169323ENST00000262843710398_531532.3333333333334736.0DomainNote=Fibronectin type-III
TgeneMID2chrX:107288409chrX:107169323ENST00000262843710516_709532.3333333333334736.0DomainB30.2/SPRY
TgeneMID2chrX:107288409chrX:107169323ENST00000443968710340_399502.3333333333333706.0DomainCOS
TgeneMID2chrX:107288409chrX:107169323ENST00000443968710398_531502.3333333333333706.0DomainNote=Fibronectin type-III
TgeneMID2chrX:107288409chrX:107169324ENST00000262843710340_399532.3333333333334736.0DomainCOS
TgeneMID2chrX:107288409chrX:107169324ENST00000262843710398_531532.3333333333334736.0DomainNote=Fibronectin type-III
TgeneMID2chrX:107288409chrX:107169324ENST00000262843710516_709532.3333333333334736.0DomainB30.2/SPRY
TgeneMID2chrX:107288409chrX:107169324ENST00000443968710340_399502.3333333333333706.0DomainCOS
TgeneMID2chrX:107288409chrX:107169324ENST00000443968710398_531502.3333333333333706.0DomainNote=Fibronectin type-III
TgeneMID2chrX:107288409chrX:107169323ENST00000262843710137_184532.3333333333334736.0Zinc fingerB box-type 1%3B degenerate
TgeneMID2chrX:107288409chrX:107169323ENST00000262843710190_232532.3333333333334736.0Zinc fingerB box-type 2
TgeneMID2chrX:107288409chrX:107169323ENST0000026284371030_80532.3333333333334736.0Zinc fingerRING-type
TgeneMID2chrX:107288409chrX:107169323ENST00000443968710137_184502.3333333333333706.0Zinc fingerB box-type 1%3B degenerate
TgeneMID2chrX:107288409chrX:107169323ENST00000443968710190_232502.3333333333333706.0Zinc fingerB box-type 2
TgeneMID2chrX:107288409chrX:107169323ENST0000044396871030_80502.3333333333333706.0Zinc fingerRING-type
TgeneMID2chrX:107288409chrX:107169324ENST00000262843710137_184532.3333333333334736.0Zinc fingerB box-type 1%3B degenerate
TgeneMID2chrX:107288409chrX:107169324ENST00000262843710190_232532.3333333333334736.0Zinc fingerB box-type 2
TgeneMID2chrX:107288409chrX:107169324ENST0000026284371030_80532.3333333333334736.0Zinc fingerRING-type
TgeneMID2chrX:107288409chrX:107169324ENST00000443968710137_184502.3333333333333706.0Zinc fingerB box-type 1%3B degenerate
TgeneMID2chrX:107288409chrX:107169324ENST00000443968710190_232502.3333333333333706.0Zinc fingerB box-type 2
TgeneMID2chrX:107288409chrX:107169324ENST0000044396871030_80502.3333333333333706.0Zinc fingerRING-type


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)
PDB file >>>438_VSIG1_107288409_MID2_107169324_ranked_0.pdbVSIG1107288409107288409ENST00000443968MID2chrX107169324+
MLGDAQQISQANLGVIEEANLRLSLVQASYWHLLLSTNLHTMVFAFWKVFLILSCLAGQPFKLDPKMTHKKLKISNDGLQMEKDESSLKK
SHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLG
260


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
VSIG1_pLDDT.png
all structure
all structure
MID2_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
all structure


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
VSIG1
MID2


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to VSIG1-MID2


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to VSIG1-MID2


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource