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	Kinase Fusion Gene Summary
	Kinase Fusion Gene Sample Information
	Kinase Fusion ORF Analysis
	Kinase Fusion Amino Acid Sequences
	Multiple Sequence Alignment of All Fusion Protein Isoforms
	Kinase Fusion Protein Functional Features
	Kinase Fusion Protein Structures
	Comparison of Fusion Protein Isoforms
	Comparison of Fusion Protein Sequences/Structures with Known Sequences/Structures from PDB
	pLDDT Scores and Difference Analysis of pLDDT Scores Between the Active Sites (Best) and Non-Active Sites.
	Ramachandran Plot of Kinase Fusion Protein Structure
	Potential Active Site Information
	Virtual Screening Results
	Kinase-Substrate Information
	Related Drugs with This Kinase Fusion Protein
	Related Disease with This Kinase Fusion Protein
	Clinical Trials of the Found Drugs/Small Molecules

Kinase Fusion Gene:BCR_ABL1

Kinase Fusion Protein Summary

Kinase Fusion gene summary

Kinase Fusion partner gene information	Kinase Fusion gene name: BCR_ABL1
	KinaseFusionDB ID: KFG587
	FusionGDB2.0 ID: KFG587
		Hgene	Tgene
	Gene symbol	BCR	ABL1
	Gene ID	613	25
	Gene name	BCR activator of RhoGEF and GTPase	ABL proto-oncogene 1, non-receptor tyrosine kinase
	Synonyms	ALL|BCR1|CML|D22S11|D22S662|PHL	ABL|BCR-ABL|CHDSKM|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl
	Cytomap	22q11.23	9q34.12
	Type of gene	protein-coding	protein-coding
	Description	breakpoint cluster region proteinBCR, RhoGEF and GTPase activating proteinBCR/FGFR1 chimera proteinFGFR1/BCR chimera proteinbreakpoint cluster regionrenal carcinoma antigen NY-REN-26	tyrosine-protein kinase ABL1ABL protooncogene 1 nonreceptor tyrosine kinaseAbelson tyrosine-protein kinase 1BCR-ABL1 p190BCR/ABL e8a2 fusionBCR/ABL1 e1a2 fusion proteinbcr/c-abl oncogene proteinc-abl oncogene 1, receptor tyrosine kinaseproto-oncog
	Modification date	20240416	20240416
	UniProtAcc	P11274	P00519
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000436990, ENST00000305877,  ENST00000359540, ENST00000398512,	ENST00000318560,
Context (manual curation of fusion genes in KinaseFusionDB)	PubMed: BCR [Title/Abstract] AND ABL1 [Title/Abstract] AND fusion [Title/Abstract] Expression of the ABL-BCR Fusion Gene in Philadelphia-Positive Acute Lymphoblastic Leukemia (pmid: 8490164) A Philadelphia-negative chronic myeloid leukemia with a BCR/ABL fusion gene on chromosome 9 (pmid: 9809034)
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	BCR(23632600)-ABL1(133729451), # samples:12 ABL1(133589842)-BCR(23634728), # samples:6

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	BCR	GO:0090630	activation of GTPase activity	7479768
Tgene	ABL1	GO:0006974	DNA damage response	15657060
Tgene	ABL1	GO:0018108	peptidyl-tyrosine phosphorylation	7590236|9144171|10713049|11121037
Tgene	ABL1	GO:0042770	signal transduction in response to DNA damage	9037071|15657060|18280240
Tgene	ABL1	GO:0043065	positive regulation of apoptotic process	9037071
Tgene	ABL1	GO:0046777	protein autophosphorylation	10713049
Tgene	ABL1	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	15657060
Tgene	ABL1	GO:0051353	positive regulation of oxidoreductase activity	12893824
Tgene	ABL1	GO:0051444	negative regulation of ubiquitin-protein transferase activity	20823226
Tgene	ABL1	GO:0070301	cellular response to hydrogen peroxide	10713049
Tgene	ABL1	GO:0071103	DNA conformation change	9558345
Tgene	ABL1	GO:0071901	negative regulation of protein serine/threonine kinase activity	11121037
Tgene	ABL1	GO:1990051	activation of protein kinase C activity	10713049
Tgene	ABL1	GO:2000042	negative regulation of double-strand break repair via homologous recombination	9461559

Kinase Fusion gene breakpoints across BCR (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Kinase Fusion gene breakpoints across ABL1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Kinase Fusion Gene Sample Information

Kinase Fusion gene information.

Kinase Fusion gene information from four resources (ChiTars 5.0, ChimerDB 4.0, COSMIC, and CCLE) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Sample	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
ChimerKB3	.	BCR	chr22	23654023	ABL1	chr9	133729451
ChiTaRS5.0	AF487522	BCR	chr22	23654023	ABL1	chr9	133729451
ChiTaRS5.0	EU394716	BCR	chr22	23652600	ABL1	chr9	133659336
ChimerKB3	.	BCR	chr22	23596172	ABL1	chr9	133762357
ChiTaRS5.0	AF533988	BCR	chr22	23596172	ABL1	chr9	133762357
ChimerDB4	AB069693	BCR	chr22	23615962	ABL1	chr9	133590436
ChiTaRS5.0	AB069693	BCR	chr22	23615962	ABL1	chr9	133590492
ChiTaRS5.0	EU394717	BCR	chr22	23615935	ABL1	chr9	133729435
ChiTaRS5.0	EU447303	BCR	chr22	23632600	ABL1	chr9	133596052
ChiTaRS5.0	FN820248	BCR	chr22	23634778	ABL1	chr9	133640908
ChiTaRS5.0	JQ425244	BCR	chr22	23632564	ABL1	chr9	133614220
ChiTaRS5.0	M19695	BCR	chr22	23632601	ABL1	chr9	133655756
ChimerKB3	.	BCR	chr22	23524426	ABL1	chr9	133738147
ChimerKB3	.	BCR	chr22	23524427	ABL1	chr9	133747512
ChimerKB3	.	BCR	chr22	23596172	ABL1	chr9	133729537
ChimerKB3	.	BCR	chr22	23603179	ABL1	chr9	133729540
ChimerKB3	.	BCR	chr22	23615961	ABL1	chr9	133729450
ChimerKB3	.	BCR	chr22	23631808	ABL1	chr9	133738148
ChimerKB3	.	BCR	chr22	23631809	ABL1	chr9	133747514
ChimerKB3	.	BCR	chr22	23632601	ABL1	chr9	133747516
ChiTaRS5.0	AF192533	BCR	chr22	23634816	ABL1	chr9	133729527
ChiTaRS5.0	DQ898313	BCR	chr22	23524426	ABL1	chr9	133738147
ChiTaRS5.0	DQ898314	BCR	chr22	23631808	ABL1	chr9	133738148
ChiTaRS5.0	DQ912588	BCR	chr22	23524427	ABL1	chr9	133747512
ChiTaRS5.0	DQ912589	BCR	chr22	23631809	ABL1	chr9	133747514
ChiTaRS5.0	DQ912590	BCR	chr22	23632601	ABL1	chr9	133747516
ChiTaRS5.0	EU216059	BCR	chr22	23603622	ABL1	chr9	133729451
ChiTaRS5.0	EU216060	BCR	chr22	23610619	ABL1	chr9	133730198
ChiTaRS5.0	EU216064	BCR	chr22	23603179	ABL1	chr9	133729540
ChiTaRS5.0	EU216070	BCR	chr22	23596172	ABL1	chr9	133729537
ChimerDB4	TCGA-AB-2817-03A	BCR	chr22	23524426	ABL1	chr9	133729451
ChimerDB4	TCGA-AB-2817	BCR	chr22	23524426	ABL1	chr9	133729450
ChimerDB4	TCGA-AB-2901-03A	BCR	chr22	23632600	ABL1	chr9	133729451
ChimerDB4	TCGA-AB-2901	BCR	chr22	23632600	ABL1	chr9	133729450
ChimerKB3	.	BCR	chr22	23524426	ABL1	chr9	133729448
ChimerKB3	.	BCR	chr22	23524426	ABL1	chr9	133729450
ChimerKB3	.	BCR	chr22	23524430	ABL1	chr9	133730185
ChimerKB3	.	BCR	chr22	23613779	ABL1	chr9	133729451
ChimerKB3	.	BCR	chr22	23631779	ABL1	chr9	133729451
ChimerKB3	.	BCR	chr22	23631808	ABL1	chr9	133729449
ChimerKB3	.	BCR	chr22	23631811	ABL1	chr9	133730186
ChimerKB3	.	BCR	chr22	23632600	ABL1	chr9	133729450
ChimerKB3	.	BCR	chr22	23632600	ABL1	chr9	133729451
ChimerKB3	.	BCR	chr22	23632602	ABL1	chr9	133730188
ChiTaRS5.0	AF113911	BCR	chr22	23524426	ABL1	chr9	133729448
ChiTaRS5.0	AJ131466	BCR	chr22	23632600	ABL1	chr9	133729451
ChiTaRS5.0	AJ131467	BCR	chr22	23631808	ABL1	chr9	133729449
ChiTaRS5.0	AM491359	BCR	chr22	23631811	ABL1	chr9	133730186
ChiTaRS5.0	AM491360	BCR	chr22	23632602	ABL1	chr9	133730188
ChiTaRS5.0	AM491361	BCR	chr22	23524430	ABL1	chr9	133730185
ChiTaRS5.0	AM491362	BCR	chr22	23613779	ABL1	chr9	133729451
ChiTaRS5.0	EF423615	BCR	chr22	23631779	ABL1	chr9	133729451
ChiTaRS5.0	KU234180	BCR	chr22	23615905	ABL1	chr9	133710870
ChiTaRS5.0	DQ898315	BCR	chr22	23632732	ABL1	chr9	133738145
ChimerKB3	.	BCR	chr22	23631881	ABL1	chr9	133729090
ChimerKB3	.	BCR	chr22	23632451	ABL1	chr9	133615066
ChimerKB3	.	BCR	chr22	23634575	ABL1	chr9	133607565
ChiTaRS5.0	AM400881	BCR	chr22	23631865	ABL1	chr9	133729719
ChiTaRS5.0	AM600680	BCR	chr22	23632358	ABL1	chr9	133729652
ChiTaRS5.0	AM886138	BCR	chr22	23632056	ABL1	chr9	133729676
ChiTaRS5.0	AY789120	BCR	chr22	23631881	ABL1	chr9	133729090
ChiTaRS5.0	FN820207	BCR	chr22	23633144	ABL1	chr9	133687480
ChiTaRS5.0	FN820208	BCR	chr22	23632390	ABL1	chr9	133660816
ChiTaRS5.0	FN820209	BCR	chr22	23633728	ABL1	chr9	133660179
ChiTaRS5.0	FN820210	BCR	chr22	23632277	ABL1	chr9	133665067
ChiTaRS5.0	FN820212	BCR	chr22	23634036	ABL1	chr9	133662857
ChiTaRS5.0	FN820213	BCR	chr22	23634138	ABL1	chr9	133601947
ChiTaRS5.0	FN820215	BCR	chr22	23631916	ABL1	chr9	133640514
ChiTaRS5.0	FN820216	BCR	chr22	23633418	ABL1	chr9	133627389
ChiTaRS5.0	FN820217	BCR	chr22	23633006	ABL1	chr9	133645620
ChiTaRS5.0	FN820218	BCR	chr22	23632754	ABL1	chr9	133608657
ChiTaRS5.0	FN820219	BCR	chr22	23632172	ABL1	chr9	133620393
ChiTaRS5.0	FN820221	BCR	chr22	23633301	ABL1	chr9	133707488
ChiTaRS5.0	FN820222	BCR	chr22	23634541	ABL1	chr9	133720348
ChiTaRS5.0	FN820223	BCR	chr22	23631960	ABL1	chr9	133594223
ChiTaRS5.0	FN820224	BCR	chr22	23632168	ABL1	chr9	133615399
ChiTaRS5.0	FN820225	BCR	chr22	23642964	ABL1	chr9	133632531
ChiTaRS5.0	FN820226	BCR	chr22	23632024	ABL1	chr9	133718268
ChiTaRS5.0	FN820227	BCR	chr22	23631888	ABL1	chr9	133688104
ChiTaRS5.0	FN820228	BCR	chr22	23632404	ABL1	chr9	133710298
ChiTaRS5.0	FN820229	BCR	chr22	23632149	ABL1	chr9	133659982
ChiTaRS5.0	FN820230	BCR	chr22	23633893	ABL1	chr9	133603228
ChiTaRS5.0	FN820231	BCR	chr22	23632055	ABL1	chr9	133637694
ChiTaRS5.0	FN820232	BCR	chr22	23632363	ABL1	chr9	133628687
ChiTaRS5.0	FN820233	BCR	chr22	23632436	ABL1	chr9	133648360
ChiTaRS5.0	FN820235	BCR	chr22	23632085	ABL1	chr9	133656686
ChiTaRS5.0	FN820236	BCR	chr22	23631879	ABL1	chr9	133704376
ChiTaRS5.0	FN820237	BCR	chr22	23634598	ABL1	chr9	133695869
ChiTaRS5.0	FN820238	BCR	chr22	23632000	ABL1	chr9	133717558
ChiTaRS5.0	FN820239	BCR	chr22	23632092	ABL1	chr9	133669183
ChiTaRS5.0	FN820240	BCR	chr22	23632409	ABL1	chr9	133724937
ChiTaRS5.0	FN820242	BCR	chr22	23634657	ABL1	chr9	133619936
ChiTaRS5.0	FN820243	BCR	chr22	23632403	ABL1	chr9	133620823
ChiTaRS5.0	FN820244	BCR	chr22	23633798	ABL1	chr9	133606780
ChiTaRS5.0	FN820245	BCR	chr22	23633141	ABL1	chr9	133517392
ChiTaRS5.0	FN820246	BCR	chr22	23631980	ABL1	chr9	133605482
ChiTaRS5.0	FN820247	BCR	chr22	23631845	ABL1	chr9	133677896
ChiTaRS5.0	FN820249	BCR	chr22	23632065	ABL1	chr9	133630729
ChiTaRS5.0	FN820250	BCR	chr22	23632677	ABL1	chr9	133721864
ChiTaRS5.0	FN820251	BCR	chr22	23632328	ABL1	chr9	133708513
ChiTaRS5.0	FN820252	BCR	chr22	23633892	ABL1	chr9	133711788
ChiTaRS5.0	FN820255	BCR	chr22	23634312	ABL1	chr9	133714311
ChiTaRS5.0	FN820257	BCR	chr22	23633633	ABL1	chr9	133722745
ChiTaRS5.0	FN820258	BCR	chr22	23633112	ABL1	chr9	133681993
ChiTaRS5.0	FN820261	BCR	chr22	23632771	ABL1	chr9	133682658
ChiTaRS5.0	FN820262	BCR	chr22	23632831	ABL1	chr9	133596999
ChiTaRS5.0	FN820263	BCR	chr22	23632387	ABL1	chr9	133610087
ChiTaRS5.0	FN820264	BCR	chr22	23631891	ABL1	chr9	133649239
ChiTaRS5.0	FN820266	BCR	chr22	23634622	ABL1	chr9	133680092
ChiTaRS5.0	FN820267	BCR	chr22	23631960	ABL1	chr9	133591499
ChiTaRS5.0	JQ425238	BCR	chr22	23634575	ABL1	chr9	133607565
ChiTaRS5.0	JQ425239	BCR	chr22	23632721	ABL1	chr9	133686163
ChiTaRS5.0	JQ425241	BCR	chr22	23633710	ABL1	chr9	133674522
ChiTaRS5.0	JQ425249	BCR	chr22	23633428	ABL1	chr9	133651603
ChiTaRS5.0	JQ425253	BCR	chr22	23632742	ABL1	chr9	133607147
ChiTaRS5.0	KR091980	BCR	chr22	23633762	ABL1	chr9	133644494
ChiTaRS5.0	KR091981	BCR	chr22	23631907	ABL1	chr9	133615409
ChiTaRS5.0	KR091983	BCR	chr22	23634316	ABL1	chr9	133656848
ChiTaRS5.0	KR091984	BCR	chr22	23634094	ABL1	chr9	133716014
ChiTaRS5.0	KR091985	BCR	chr22	23632972	ABL1	chr9	133645075
ChiTaRS5.0	KR091986	BCR	chr22	23634698	ABL1	chr9	133618150
ChiTaRS5.0	KR091987	BCR	chr22	23634664	ABL1	chr9	133604081
ChiTaRS5.0	KR091988	BCR	chr22	23632035	ABL1	chr9	133679658
ChiTaRS5.0	KR091989	BCR	chr22	23633009	ABL1	chr9	133634547
ChiTaRS5.0	KR091990	BCR	chr22	23633604	ABL1	chr9	133716816
ChiTaRS5.0	KR091991	BCR	chr22	23633295	ABL1	chr9	133716070
ChiTaRS5.0	KR091992	BCR	chr22	23633170	ABL1	chr9	133517392
ChiTaRS5.0	KR091993	BCR	chr22	23633012	ABL1	chr9	133606669
ChiTaRS5.0	KR091994	BCR	chr22	23633568	ABL1	chr9	133590657
ChiTaRS5.0	KR091995	BCR	chr22	23634167	ABL1	chr9	133650106
ChiTaRS5.0	KR091996	BCR	chr22	23634065	ABL1	chr9	133724686
ChiTaRS5.0	KR091997	BCR	chr22	23632492	ABL1	chr9	133653642
ChiTaRS5.0	KR091998	BCR	chr22	23633886	ABL1	chr9	133726837
ChiTaRS5.0	KR091999	BCR	chr22	23633966	ABL1	chr9	133651678
ChiTaRS5.0	KR092000	BCR	chr22	23632628	ABL1	chr9	133589802
ChiTaRS5.0	KR092001	BCR	chr22	23632963	ABL1	chr9	133658788
ChiTaRS5.0	KR092002	BCR	chr22	23634207	ABL1	chr9	133616461
ChiTaRS5.0	KR092004	BCR	chr22	23634567	ABL1	chr9	133598296
ChiTaRS5.0	KR092005	BCR	chr22	23633637	ABL1	chr9	133644370
ChiTaRS5.0	KR092006	BCR	chr22	23634681	ABL1	chr9	133660338
ChiTaRS5.0	KR092007	BCR	chr22	23632179	ABL1	chr9	133629979
ChiTaRS5.0	KR092008	BCR	chr22	23632432	ABL1	chr9	133677059
ChiTaRS5.0	KR092009	BCR	chr22	23633071	ABL1	chr9	133635337
ChiTaRS5.0	KR092010	BCR	chr22	23633539	ABL1	chr9	133601330
ChiTaRS5.0	KR092011	BCR	chr22	23632926	ABL1	chr9	133616518
ChiTaRS5.0	KR092012	BCR	chr22	23632255	ABL1	chr9	133643802
ChiTaRS5.0	KR092013	BCR	chr22	23634546	ABL1	chr9	133722214
ChiTaRS5.0	KR092014	BCR	chr22	23634226	ABL1	chr9	133679583
ChiTaRS5.0	KR092015	BCR	chr22	23633667	ABL1	chr9	133590447
ChiTaRS5.0	KR092016	BCR	chr22	23633610	ABL1	chr9	133644123
ChiTaRS5.0	KR092017	BCR	chr22	23632664	ABL1	chr9	133719046
ChiTaRS5.0	KR092018	BCR	chr22	23634603	ABL1	chr9	133717382
ChiTaRS5.0	KR092019	BCR	chr22	23633973	ABL1	chr9	133696184
ChiTaRS5.0	KR092020	BCR	chr22	23633919	ABL1	chr9	133590709
ChiTaRS5.0	KR092022	BCR	chr22	23634507	ABL1	chr9	133592438
ChiTaRS5.0	KR092023	BCR	chr22	23633830	ABL1	chr9	133662471
ChiTaRS5.0	KR092024	BCR	chr22	23632152	ABL1	chr9	133663835
ChiTaRS5.0	M31759	BCR	chr22	23633068	ABL1	chr9	133697851
ChiTaRS5.0	U19399	BCR	chr22	23632845	ABL1	chr9	133727499
ChiTaRS5.0	U19400	BCR	chr22	23633595	ABL1	chr9	133705632
ChiTaRS5.0	U19406	BCR	chr22	23631916	ABL1	chr9	133722533
ChiTaRS5.0	U19408	BCR	chr22	23632451	ABL1	chr9	133615066
COSMIC	2319283	BCR	chr22	23615961	ABL1	chr9	133729451
COSMIC	2319284	BCR	chr22	23631760	ABL1	chr9	133710913
COSMIC	2319478	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2319564	BCR	chr22	23596082	ABL1	chr9	133710840
COSMIC	2319565	BCR	chr22	23596082	ABL1	chr9	133710840
COSMIC	2319566	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324038	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2324039	BCR	chr22	23524426	ABL1	chr9	133730188
COSMIC	2324169	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324170	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324171	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324172	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324173	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324174	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324175	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324176	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324177	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324178	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324179	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324180	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324181	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324182	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324183	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324184	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324185	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324186	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324187	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324188	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324189	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324190	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324191	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324192	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324193	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324194	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324195	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324196	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324197	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324198	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324199	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324200	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324201	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324202	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324203	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324204	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324205	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324206	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324207	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324208	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324209	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324210	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324211	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324212	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324213	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324214	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324215	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324216	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324217	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324218	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324219	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324220	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324221	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324222	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324223	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324224	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324225	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324226	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324227	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324228	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324229	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324230	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324231	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324232	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324233	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324234	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324235	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324236	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324237	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324238	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324239	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324240	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324241	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324242	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324243	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324244	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324245	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324246	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324247	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324248	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324249	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324250	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324251	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324252	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324253	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324254	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324255	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324256	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324257	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324258	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324259	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324260	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324261	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324262	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324263	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324264	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324265	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324266	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324267	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324268	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324269	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324270	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2324271	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329113	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329432	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329433	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329434	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329435	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329436	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329437	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329438	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329439	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329440	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329441	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329442	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329443	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329444	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329445	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329446	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329447	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329448	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329449	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329450	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329451	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329452	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329453	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329454	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329455	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329456	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329457	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329458	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329459	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329460	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329461	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329462	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329463	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329464	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329465	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329466	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329467	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329468	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329469	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329470	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329471	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329472	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329473	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329474	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329475	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329476	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329477	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329478	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329479	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329480	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329481	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329482	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329483	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329484	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329485	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329486	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329487	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329488	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329489	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329490	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329491	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329492	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329493	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329494	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329495	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329496	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329497	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329498	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329499	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329500	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329501	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329502	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329503	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329504	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329505	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329506	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329507	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329508	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329509	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329510	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329511	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329512	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329513	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329514	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329515	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329516	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329517	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329518	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329519	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329520	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329521	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329522	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329523	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329524	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329525	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329526	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329527	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329528	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329529	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329530	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329531	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329532	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329533	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329534	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329535	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329536	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329537	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329538	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329539	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329540	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329541	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329542	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329543	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329544	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329545	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329546	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329547	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329548	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329549	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329550	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329551	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329552	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329553	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329554	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329555	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329556	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329557	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329558	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329559	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329560	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329561	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329562	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329563	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329564	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329565	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329566	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329567	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329568	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329569	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329570	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329571	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329572	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329573	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329574	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329575	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329576	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329577	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329578	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329579	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329580	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329581	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329582	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329583	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329584	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329585	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329586	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329587	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329588	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329589	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329590	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329591	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329592	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329593	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329594	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329595	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329596	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329597	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329598	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329599	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329600	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329601	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329602	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329603	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329604	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329605	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329606	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329607	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329608	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329609	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329610	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329611	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329612	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329613	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329614	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329615	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329616	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329617	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329618	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329619	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329620	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329621	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329622	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329623	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329624	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329625	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329626	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329627	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329628	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329629	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329630	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329631	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329632	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329633	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329634	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329635	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329636	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329637	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329638	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329639	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329640	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329641	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329642	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329643	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329644	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329645	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329646	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329647	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329648	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329649	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329650	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329651	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329652	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329653	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329654	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329655	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329656	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329657	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329658	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329659	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329660	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329661	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329662	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329663	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329664	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329665	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329666	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329667	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329668	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329669	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329670	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329671	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329672	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329673	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329674	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329675	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329676	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329677	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329678	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329679	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329680	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329681	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329682	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329683	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329684	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329685	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329686	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329687	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329688	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329689	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329690	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329691	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329692	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329693	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329694	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329695	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329696	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329697	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329698	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329699	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329700	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329701	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329702	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329703	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329704	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329705	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329706	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329707	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329708	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329709	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329710	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329711	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329712	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329713	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329714	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329715	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329716	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329717	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329718	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329719	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329720	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329721	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329722	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329723	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329724	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329725	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329726	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329727	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329728	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329729	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329730	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329731	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329732	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329733	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329734	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329735	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329736	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329737	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329738	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329739	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329740	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329741	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329742	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329743	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329744	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329745	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329746	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329747	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329748	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329749	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329750	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329751	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329752	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329753	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329754	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329755	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329756	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329757	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329758	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329759	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329760	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329761	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329762	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329763	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329764	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329765	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329766	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329767	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329768	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329769	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329770	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329771	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329772	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329773	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329774	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329775	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329776	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329777	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329778	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329779	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329780	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329781	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329782	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329783	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329784	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329785	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329786	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329787	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329788	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329789	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329790	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329791	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329792	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329793	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329794	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329795	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329796	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329797	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329798	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329799	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329800	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329801	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329802	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329803	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329804	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329805	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329806	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329807	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329808	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329809	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329810	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329811	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329812	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329813	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329814	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329815	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329816	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329817	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329818	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329819	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329820	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329821	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329822	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329823	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329824	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329825	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329826	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329827	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329828	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329829	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329830	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329831	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329832	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329833	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329834	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329835	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329836	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329837	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329838	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329839	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329840	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329841	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329842	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329843	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329844	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329845	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329846	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329847	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329848	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329849	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329850	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329851	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329852	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329853	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329854	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329855	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329856	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329857	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329858	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329859	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329860	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329861	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329862	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329863	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329864	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329865	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329866	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329867	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329868	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329869	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329870	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329871	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329872	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329873	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329874	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329875	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329876	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329877	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329878	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329879	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329880	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2329881	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2332622	BCR	chr22	23631808	ABL1	chr9	133730188
COSMIC	2332623	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2332624	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2332625	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2332626	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2346030	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346031	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346032	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346033	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346034	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346035	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346036	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346037	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346038	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346039	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346040	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346041	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346042	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346043	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346044	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346045	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2346955	BCR	chr22	23631808	ABL1	chr9	133730188
COSMIC	2346956	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2347551	BCR	chr22	23524426	ABL1	chr9	133730188
COSMIC	2347552	BCR	chr22	23524426	ABL1	chr9	133730188
COSMIC	2348707	BCR	chr22	23524426	ABL1	chr9	133730188
COSMIC	2348927	BCR	chr22	23524426	ABL1	chr9	133730188
COSMIC	2348928	BCR	chr22	23631808	ABL1	chr9	133730188
COSMIC	2348954	BCR	chr22	23631808	ABL1	chr9	133730188
COSMIC	2350658	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350659	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350660	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350661	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350662	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350663	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350664	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350665	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350666	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350692	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350797	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350798	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350799	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350800	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350801	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350802	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350803	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350804	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350805	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350806	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350807	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350808	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350809	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350810	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350811	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350812	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350813	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350855	BCR	chr22	23654023	ABL1	chr9	133710453
COSMIC	2350858	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350859	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350860	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350861	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350862	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350863	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350864	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350865	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350866	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350867	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350868	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350869	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350870	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350871	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350872	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350873	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350874	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350875	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350876	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350877	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350878	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350879	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350880	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350881	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350882	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350883	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350884	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350885	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350886	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350887	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350888	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350889	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350890	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350891	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350892	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2350948	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352378	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352379	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352380	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352381	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352382	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352383	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352384	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352385	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352386	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352387	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352388	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352389	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352390	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352391	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352392	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352393	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352394	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352395	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352396	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352397	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352398	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352399	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352400	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352401	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352402	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352403	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352404	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352405	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352406	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352407	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352408	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352409	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352410	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352411	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352412	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352413	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352414	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352415	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352416	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352417	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352418	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352419	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352420	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352421	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352422	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352423	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352424	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352425	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352426	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352427	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352428	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352429	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352443	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352455	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352456	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352457	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352458	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352459	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352460	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352461	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352814	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352815	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352816	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352817	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352818	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352819	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352820	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352821	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352822	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352823	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352824	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352825	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352826	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352827	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352828	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352829	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352830	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352831	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352832	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352833	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352834	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352835	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352836	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352837	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352838	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352839	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352840	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352841	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352842	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352898	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352899	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352900	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352901	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352902	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352903	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352904	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352905	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352906	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352907	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352908	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352909	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352910	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352911	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352912	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352913	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2352914	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2352915	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2352916	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2352917	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2352918	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2352919	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2352926	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352927	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352928	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352929	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352930	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352931	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352932	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352933	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352934	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352935	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352936	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352937	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352938	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352939	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352940	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352941	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352942	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352943	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352944	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352945	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352946	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352947	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2352948	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353418	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2353419	BCR	chr22	23632600	ABL1	chr9	133730188
COSMIC	2353562	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353563	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353564	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353565	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353566	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353567	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353568	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353569	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353570	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353571	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353572	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353573	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353597	BCR	chr22	23631808	ABL1	chr9	133730188
COSMIC	2353606	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353607	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353610	BCR	chr22	23524426	ABL1	chr9	133730188
COSMIC	2353611	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353612	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353613	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353614	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353615	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353616	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353617	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353618	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353619	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353620	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353621	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353622	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353623	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353624	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353625	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353626	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353627	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353628	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353629	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353630	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353631	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353632	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353633	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353634	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353635	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353636	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353637	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353638	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353639	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353640	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353641	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353642	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353643	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353644	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353645	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353646	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353647	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353648	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353649	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353650	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353651	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353652	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353653	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353654	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353655	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353656	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353657	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353658	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353659	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353660	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353661	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353662	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353663	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353664	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353665	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353666	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353667	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353668	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353669	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353670	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353671	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353672	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353673	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353674	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353675	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353676	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353677	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353678	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353679	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353680	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353681	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353682	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353683	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353684	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353685	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353686	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353687	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353688	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353689	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353690	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353691	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353692	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353693	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353694	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353695	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353696	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353697	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353698	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353699	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353700	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353701	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353702	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353703	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353704	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353705	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353706	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353707	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353708	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353709	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353710	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353711	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353712	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353713	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353714	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353715	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353716	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353717	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353718	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353719	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353720	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353721	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353722	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353723	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353724	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353725	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353726	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353727	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353728	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353729	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2353730	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354154	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354155	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354156	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354157	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354158	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354159	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354160	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354161	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354162	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354163	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354164	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354165	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354166	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354167	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354168	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354169	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354170	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354171	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354172	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354173	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354174	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354175	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354176	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354177	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354178	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354179	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354180	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354181	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354182	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354183	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354184	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354185	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354186	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354187	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354188	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354189	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354190	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354249	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354250	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354251	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354252	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354253	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354254	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354255	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354256	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354257	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354258	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354259	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354260	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354261	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354262	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354263	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2354264	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356048	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356107	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356108	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356109	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356110	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356111	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356112	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356113	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356114	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356115	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356116	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356117	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356118	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356119	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356120	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356121	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356122	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356123	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356124	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356125	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356126	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356127	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356128	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356129	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356130	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356131	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356132	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356133	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356134	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356135	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356136	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356137	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356138	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356139	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356140	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356141	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356142	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356143	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356144	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356145	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356146	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356147	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356148	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356149	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356150	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356252	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356253	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356254	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356255	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356256	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356257	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356258	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356259	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356260	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356261	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356262	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356263	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356264	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356265	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356266	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356267	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356268	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356269	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356270	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356271	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356272	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356273	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356274	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356275	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356276	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356277	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356278	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356279	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356280	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356281	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356282	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356283	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356284	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2356285	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357151	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357305	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357306	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357307	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357308	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357309	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357310	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357311	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357312	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357313	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357314	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357315	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357316	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357317	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357318	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357319	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357320	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357321	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357322	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357323	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357324	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357325	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357326	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357327	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357328	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357329	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357330	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357331	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357332	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357333	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357334	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357335	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357336	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357337	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357338	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357339	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357340	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357341	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357342	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357343	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357344	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357345	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357346	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357347	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357348	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357349	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357350	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357351	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357352	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357353	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357354	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357355	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357356	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357357	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357358	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357359	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357360	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357361	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357362	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357363	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357364	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357365	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357366	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357367	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357368	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357430	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357431	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357432	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357433	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357434	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357435	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357436	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357437	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357438	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357439	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357440	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357441	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357442	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357443	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357444	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357445	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357446	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357447	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357448	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357449	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357450	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357451	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357452	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357453	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357454	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357455	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357456	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357457	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357458	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357459	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357460	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357461	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357462	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357463	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357464	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357465	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357466	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357467	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357468	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357469	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357470	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357471	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357472	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357473	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357474	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357475	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357476	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357477	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357478	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357479	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357480	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357481	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357482	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357483	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357484	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357723	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357724	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357725	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357726	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357727	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357728	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357729	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357730	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357731	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357732	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357733	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357734	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357735	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357736	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357737	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357738	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357739	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357740	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357741	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357742	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357743	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357744	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357745	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357746	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357747	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357748	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357749	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357750	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357751	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357752	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357753	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357754	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357755	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2357756	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358237	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358238	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358239	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358240	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358241	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358242	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358243	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358244	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358245	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358246	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358247	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358248	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358249	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358250	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358251	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358252	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358253	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358254	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358255	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358256	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358257	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358258	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358259	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358260	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358261	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358262	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358263	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358264	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358265	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358266	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358267	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358268	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358269	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358355	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358356	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358357	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358358	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358359	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358360	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358361	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358362	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358363	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358364	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358365	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358366	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358367	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358368	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358369	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358370	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358371	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358372	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358373	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358374	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358375	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358376	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358377	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358378	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358379	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358380	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358381	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358382	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358383	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358384	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358385	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358386	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358387	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358388	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358389	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358390	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358391	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358392	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358393	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358394	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358395	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358396	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358397	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358398	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358399	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358400	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358401	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358521	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358522	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358523	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358524	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358525	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358526	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358527	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358528	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2358530	BCR	chr22	23524426	ABL1	chr9	133730188
COSMIC	2358532	BCR	chr22	23524426	ABL1	chr9	133730188
COSMIC	2358533	BCR	chr22	23524426	ABL1	chr9	133730188
COSMIC	2358534	BCR	chr22	23631838	ABL1	chr9	133729671
COSMIC	2360685	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360686	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360687	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360688	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360689	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360690	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360691	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360692	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360693	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360694	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360695	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360696	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360697	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360698	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360699	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360700	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360701	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360702	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360703	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360704	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360705	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360739	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360740	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360741	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360742	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360743	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360744	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360745	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360746	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360747	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360748	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360749	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360750	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360751	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360752	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360753	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360754	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360755	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360756	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360757	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360758	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360759	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360760	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360761	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360762	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360763	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360764	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360765	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360766	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360767	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360768	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360769	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360770	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360771	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360794	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360795	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360796	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360797	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360798	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360799	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360800	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360801	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360802	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360803	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360804	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360805	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360806	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360807	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360808	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360809	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360810	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360811	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360812	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360813	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360814	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360815	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360816	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360817	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360818	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360819	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360820	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360821	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360822	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360823	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360824	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360825	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2360826	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363133	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363134	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363135	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363136	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363137	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363138	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363139	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363140	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363141	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363142	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363143	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363144	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363145	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363146	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363147	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363148	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363149	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363150	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363151	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363152	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363153	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363154	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363155	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363156	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363157	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363158	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363159	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363160	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363161	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363162	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363163	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363164	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363165	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363166	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363167	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363168	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363169	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363170	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363171	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363172	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363173	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363174	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363175	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363176	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363177	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363178	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363179	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363180	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363181	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363182	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363183	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363184	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363185	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363186	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363187	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363188	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363189	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363190	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363191	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363192	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363193	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363194	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363195	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363196	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363197	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363198	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363199	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363200	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363201	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363202	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363203	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363204	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363205	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363206	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363207	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363208	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363209	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363210	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363211	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363212	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363213	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363214	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363215	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363216	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363217	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363218	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363219	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363220	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363221	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363222	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363223	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363224	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363225	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363226	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363227	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363228	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363229	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363230	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363231	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363232	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363233	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363234	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363235	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363236	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363237	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363238	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363239	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363240	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363241	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363242	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363243	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363244	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363245	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363246	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363247	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363248	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363249	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363250	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363251	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363252	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363253	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363254	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363255	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363256	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363257	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363258	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363259	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363260	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363261	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363262	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363263	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363264	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363265	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363266	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363267	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363268	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363269	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363270	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363271	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363272	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363273	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363274	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363275	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363276	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363277	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363278	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363279	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363280	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363281	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363282	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363283	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363284	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363285	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363286	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363287	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363288	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363289	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363290	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363291	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363292	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363293	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363294	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363295	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363296	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363297	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363298	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363299	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363300	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363301	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363302	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363303	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363304	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363305	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363306	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2363308	BCR	chr22	23524426	ABL1	chr9	133730188
COSMIC	2363309	BCR	chr22	23631808	ABL1	chr9	133730188
COSMIC	2364001	BCR	chr22	23655067	ABL1	chr9	133710913
COSMIC	2364004	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2364005	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367171	BCR	chr22	23615961	ABL1	chr9	133710913
COSMIC	2367172	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367173	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367174	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367175	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367176	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367177	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367178	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367179	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367180	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367181	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367182	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367183	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367184	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367185	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367186	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367187	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367188	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367189	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367190	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367191	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367192	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367193	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367194	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367195	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367196	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367197	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367198	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367199	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367200	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367201	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367202	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2367203	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368716	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368717	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368718	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368719	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368720	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368721	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368724	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368725	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368726	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368727	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368728	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368729	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368730	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368731	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368732	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368733	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368736	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368737	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368747	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368748	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368749	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368756	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2368757	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369367	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369368	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369369	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369370	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369371	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369372	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369373	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369374	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369375	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369376	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369377	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369378	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369379	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369380	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369381	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369382	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369383	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369384	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369385	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369386	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369387	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369388	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369389	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369390	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369391	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369392	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369393	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369394	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369395	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369396	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369397	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369398	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369501	BCR	chr22	23631808	ABL1	chr9	133730188
COSMIC	2369509	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369513	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369514	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369648	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369649	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369650	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369651	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369652	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369653	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369675	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369676	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369677	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369678	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369679	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369680	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369681	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369682	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369683	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369684	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369693	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369694	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369696	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369707	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369708	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369709	BCR	chr22	23631897	ABL1	chr9	133725055
COSMIC	2369710	BCR	chr22	23631897	ABL1	chr9	133725055
COSMIC	2369711	BCR	chr22	23631897	ABL1	chr9	133725055
COSMIC	2369712	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369713	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369714	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369715	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369716	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369717	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369718	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369719	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369720	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369721	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369722	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369723	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369724	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369725	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369726	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369727	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369728	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369729	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369730	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369731	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369732	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369733	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369734	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369735	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369736	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369737	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369738	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369739	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369740	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369741	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369742	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369743	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369744	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369745	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369746	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369747	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369748	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369749	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369750	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369836	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369837	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369838	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369839	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369840	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369841	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369842	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369843	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369844	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369845	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369846	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369847	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369848	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369849	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369850	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369851	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369852	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2369853	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370421	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370422	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370423	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370424	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370425	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370426	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370427	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370428	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370429	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370430	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370431	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370432	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370433	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370434	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370435	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370436	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370437	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370438	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370439	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370440	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370441	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370442	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370443	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370444	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370445	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370446	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370447	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370448	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370449	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370450	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370451	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2370620	BCR	chr22	23634825	ABL1	chr9	133710453
COSMIC	2370621	BCR	chr22	23634825	ABL1	chr9	133710453
COSMIC	2370622	BCR	chr22	23603241	ABL1	chr9	133710913
COSMIC	2370623	BCR	chr22	23596167	ABL1	chr9	133729451
COSMIC	2371682	BCR	chr22	23615961	ABL1	chr9	133729435
COSMIC	2371683	BCR	chr22	23615961	ABL1	chr9	133729435
COSMIC	2371684	BCR	chr22	23615961	ABL1	chr9	133729435
COSMIC	2371685	BCR	chr22	23615961	ABL1	chr9	133729435
COSMIC	2375575	BCR	chr22	23654105	ABL1	chr9	133729035
COSMIC	2375707	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375708	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375709	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375710	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375711	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375712	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375713	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375714	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375715	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375716	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375717	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375718	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375719	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375720	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375721	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375722	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375723	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375724	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375725	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375726	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375727	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375728	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375729	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375730	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375731	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375732	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375733	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375734	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375735	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375736	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375737	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375738	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375797	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375798	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375799	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375800	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375801	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375802	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375803	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375804	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375805	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375806	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375807	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375808	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375809	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375810	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375811	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375812	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375813	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375814	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375815	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375816	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375817	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375818	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375819	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375820	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375821	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375822	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375823	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375824	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2375825	BCR	chr22	23631808	ABL1	chr9	133729451
COSMIC	2689001	BCR	chr22	23631808	ABL1	chr9	133729451
CCLE	HAP1	BCR	chr22	23631808	ABL1	chr9	133729451
CCLE	NCO2	BCR	chr22	23631808	ABL1	chr9	133729451
CCLE	KCL-22	BCR	chr22	23631808	ABL1	chr9	133729451
CCLE	BV-173	BCR	chr22	23631808	ABL1	chr9	133729451
CCLE	MOLM-1	BCR	chr22	23631808	ABL1	chr9	133729451
CCLE	KYO-1	BCR	chr22	23631808	ABL1	chr9	133729451
CCLE	JK-1	BCR	chr22	23631808	ABL1	chr9	133729451
CCLE	MEG-01	BCR	chr22	23631808	ABL1	chr9	133729451
CCLE	NALM-1	BCR	chr22	23631808	ABL1	chr9	133729451
CCLE	MOLM-6	BCR	chr22	23631808	ABL1	chr9	133729451
CCLE	CML-T1	BCR	chr22	23631808	ABL1	chr9	133729451

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Kinase Fusion ORF Analysis

Kinase Fusion information from ORFfinder translation from full-length transcript sequence from KinaseFusionDB.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (amino acids)
ENST00000305877	ENST00000318560	BCR	chr22	23632600	ABL1	chr9	133730188	8665	1973
ENST00000305877	ENST00000318560	BCR	chr22	23631808	ABL1	chr9	133729451	8764	2006
ENST00000305877	ENST00000318560	BCR	chr22	23631808	ABL1	chr9	133730188	8590	1948
ENST00000305877	ENST00000318560	BCR	chr22	23634825	ABL1	chr9	133710453	9397	1167
ENST00000305877	ENST00000318560	BCR	chr22	23632600	ABL1	chr9	133729451	8839	2031
ENST00000305877	ENST00000318560	BCR	chr22	23632600	ABL1	chr9	133729450	8839	2031
ENST00000305877	ENST00000318560	BCR	chr22	23654023	ABL1	chr9	133729451	9379	2211
ENST00000305877	ENST00000318560	BCR	chr22	23631808	ABL1	chr9	133729449	8764	2006
ENST00000305877	ENST00000318560	BCR	chr22	23631811	ABL1	chr9	133730186	8590	1948
ENST00000305877	ENST00000318560	BCR	chr22	23632602	ABL1	chr9	133730188	8665	1973
ENST00000305877	ENST00000318560	BCR	chr22	23596082	ABL1	chr9	133710840	7493	1125
ENST00000305877	ENST00000318560	BCR	chr22	23524426	ABL1	chr9	133730188	7162	1472
ENST00000305877	ENST00000318560	BCR	chr22	23524426	ABL1	chr9	133729451	7336	1530
ENST00000305877	ENST00000318560	BCR	chr22	23524426	ABL1	chr9	133729450	7336	1530
ENST00000305877	ENST00000318560	BCR	chr22	23524426	ABL1	chr9	133729448	7336	1530
ENST00000305877	ENST00000318560	BCR	chr22	23524430	ABL1	chr9	133730185	7162	1472
ENST00000305877	ENST00000318560	BCR	chr22	23613779	ABL1	chr9	133729451	7978	1744
ENST00000305877	ENST00000318560	BCR	chr22	23631779	ABL1	chr9	133729451	8688	1110
ENST00000305877	ENST00000318560	BCR	chr22	23615905	ABL1	chr9	133710870	8129	1114

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Kinase Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from KinaseFusionDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>Henst_Tenst_Hgene_Hchr_Hbp_Tgene_Tchr_Tbp_length(fusion AA)_AAseq >ENST00000305877_ENST00000318560_BCR_chr22_23632600_ABL1_chr9_133730188_length(amino acids)=1973 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSSEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGING SFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEM ERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL RECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFS IKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVE KELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKT NLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLW KKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTR GTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSK GPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKK PVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNS -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23631808_ABL1_chr9_133729451_length(amino acids)=2006 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSN YITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST VADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIK HPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGL SRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRA CWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDH EPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTA DPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTG RQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKE EAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAG EAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRK TRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATA -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23631808_ABL1_chr9_133730188_length(amino acids)=1948 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY HYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWK KYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAME YLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPG IDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKT RTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFR EMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKR FLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIM ESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKL SRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVP STLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVD -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23634825_ABL1_chr9_133710453_length(amino acids)=1167 MAGPGAPGGRAGRAGPEPGPRTELGEGFRPPTCWRGKMLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKEN LLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSS GINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYD KWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNL LDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAY NKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSIS DEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPK DKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRS PHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSD QVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPG GTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGE GLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAI -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23632600_ABL1_chr9_133729451_length(amino acids)=2031 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSKALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLR VLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA SDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVA VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNF IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY ELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAA EHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPE RRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSA SCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSS PPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAP PPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSAS SALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRN -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23632600_ABL1_chr9_133729450_length(amino acids)=2031 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSKALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLR VLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA SDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVA VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNF IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY ELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAA EHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPE RRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSA SCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSS PPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAP PPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSAS SALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRN -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23654023_ABL1_chr9_133729451_length(amino acids)=2211 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKED GESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIER RGMEEVGIYRVSGVATDIQALKAAFDVKALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLR VLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA SDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVA VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNF IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY ELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAA EHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPE RRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSA SCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSS PPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAP PPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSAS SALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRN -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23631808_ABL1_chr9_133729449_length(amino acids)=2006 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSN YITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST VADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIK HPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGL SRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRA CWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDH EPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTA DPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTG RQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKE EAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAG EAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRK TRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATA -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23631811_ABL1_chr9_133730186_length(amino acids)=1948 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY HYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWK KYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAME YLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPG IDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKT RTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFR EMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKR FLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIM ESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKL SRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVP STLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVD -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23632602_ABL1_chr9_133730188_length(amino acids)=1973 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSSEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGING SFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEM ERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL RECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFS IKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVE KELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKT NLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLW KKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTR GTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSK GPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKK PVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNS -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23596082_ABL1_chr9_133710840_length(amino acids)=1125 MKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNH NGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY VSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKE DTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLA ARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKD YRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTT DVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGE EEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHG AKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTP KPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAA SAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGD QPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFRE -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23524426_ABL1_chr9_133730188_length(amino acids)=1472 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDAGEKLRVLGYNHNGEWCEAQTKNGQ GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAEL VHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVK VADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKV YELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGE SDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAF TPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPR DLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPAS GLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSP SQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLIST RVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQ -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23524426_ABL1_chr9_133729451_length(amino acids)=1530 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDAEALQRPVASDFEPQGLSEAARWNS KENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYL LSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSP NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTY GNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPES LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES SISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERL LPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSG FRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGEN RSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSG APGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQ PGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALC LAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23524426_ABL1_chr9_133729450_length(amino acids)=1530 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDAEALQRPVASDFEPQGLSEAARWNS KENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYL LSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSP NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTY GNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPES LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES SISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERL LPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSG FRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGEN RSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSG APGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQ PGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALC LAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23524426_ABL1_chr9_133729448_length(amino acids)=1530 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDAEALQRPVASDFEPQGLSEAARWNS KENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYL LSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSP NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTY GNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPES LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES SISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERL LPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSG FRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGEN RSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSG APGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQ PGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALC LAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23524430_ABL1_chr9_133730185_length(amino acids)=1472 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDAGEKLRVLGYNHNGEWCEAQTKNGQ GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAEL VHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVK VADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKV YELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGE SDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAF TPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPR DLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPAS GLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSP SQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLIST RVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQ -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23613779_ABL1_chr9_133729451_length(amino acids)=1744 MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLEKALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKN GQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLA ELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKE AAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHL VKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPE KVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQ GESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGAL AFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTL PRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAP ASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQ SPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLI STRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRE -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23631779_ABL1_chr9_133729451_length(amino acids)=1110 MTINKEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGW VPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVH HHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVA DFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYE LMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESD PLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTP LDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDL QSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGL PHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQ EAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRV SLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQIC -------------------------------------------------------------- >ENST00000305877_ENST00000318560_BCR_chr22_23615905_ABL1_chr9_133710870_length(amino acids)=1114 MSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKN GQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLA ELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKE AAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHL VKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPE KVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQ GESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGAL AFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTL PRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAP ASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQ SPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLI STRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRE --------------------------------------------------------------

Multiple Sequence Alignment of All Fusion Protein Isoforms

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Kinase Fusion Protein Functional Features

Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:23632600/chr9:133729451) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
BCR P11274	ABL1 P00519
FUNCTION: Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein (GAP) domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form (PubMed:7479768, PubMed:1903516, PubMed:17116687). The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form (PubMed:7479768, PubMed:23940119). The amino terminus contains an intrinsic kinase activity (PubMed:1657398). Functions as an important negative regulator of neuronal RAC1 activity (By similarity). Regulates macrophage functions such as CSF1-directed motility and phagocytosis through the modulation of RAC1 activity (PubMed:17116687). Plays a major role as a RHOA GEF in keratinocytes being involved in focal adhesion formation and keratinocyte differentiation (PubMed:23940119). {ECO:0000250|UniProtKB:Q6PAJ1, ECO:0000269|PubMed:1657398, ECO:0000269|PubMed:17116687, ECO:0000269|PubMed:1903516, ECO:0000269|PubMed:23940119, ECO:0000269|PubMed:7479768}.	FUNCTION: Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation); ANXA1 (involved in membrane anchoring); DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling); or MAPT and PXN (microtubule-binding proteins). Phosphorylation of WASF3 is critical for the stimulation of lamellipodia formation and cell migration. Involved in the regulation of cell adhesion and motility through phosphorylation of key regulators of these processes such as BCAR1, CRK, CRKL, DOK1, EFS or NEDD9 (PubMed:22810897). Phosphorylates multiple receptor tyrosine kinases and more particularly promotes endocytosis of EGFR, facilitates the formation of neuromuscular synapses through MUSK, inhibits PDGFRB-mediated chemotaxis and modulates the endocytosis of activated B-cell receptor complexes. Other substrates which are involved in endocytosis regulation are the caveolin (CAV1) and RIN1. Moreover, ABL1 regulates the CBL family of ubiquitin ligases that drive receptor down-regulation and actin remodeling. Phosphorylation of CBL leads to increased EGFR stability. Involved in late-stage autophagy by regulating positively the trafficking and function of lysosomal components. ABL1 targets to mitochondria in response to oxidative stress and thereby mediates mitochondrial dysfunction and cell death. In response to oxidative stress, phosphorylates serine/threonine kinase PRKD2 at 'Tyr-717' (PubMed:28428613). ABL1 is also translocated in the nucleus where it has DNA-binding activity and is involved in DNA-damage response and apoptosis. Many substrates are known mediators of DNA repair: DDB1, DDB2, ERCC3, ERCC6, RAD9A, RAD51, RAD52 or WRN. Activates the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates TP73, a primary regulator for this type of damage-induced apoptosis. Phosphorylates the caspase CASP9 on 'Tyr-153' and regulates its processing in the apoptotic response to DNA damage. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. ABL1 acts also as a regulator of multiple pathological signaling cascades during infection. Several known tyrosine-phosphorylated microbial proteins have been identified as ABL1 substrates. This is the case of A36R of Vaccinia virus, Tir (translocated intimin receptor) of pathogenic E.coli and possibly Citrobacter, CagA (cytotoxin-associated gene A) of H.pylori, or AnkA (ankyrin repeat-containing protein A) of A.phagocytophilum. Pathogens can highjack ABL1 kinase signaling to reorganize the host actin cytoskeleton for multiple purposes, like facilitating intracellular movement and host cell exit. Finally, functions as its own regulator through autocatalytic activity as well as through phosphorylation of its inhibitor, ABI1. Regulates T-cell differentiation in a TBX21-dependent manner (By similarity). Positively regulates chemokine-mediated T-cell migration, polarization, and homing to lymph nodes and immune-challenged tissues, potentially via activation of NEDD9/HEF1 and RAP1 (By similarity). Phosphorylates TBX21 on tyrosine residues leading to an enhancement of its transcriptional activator activity (By similarity). {ECO:0000250|UniProtKB:P00520, ECO:0000269|PubMed:10391250, ECO:0000269|PubMed:11971963, ECO:0000269|PubMed:12379650, ECO:0000269|PubMed:12531427, ECO:0000269|PubMed:12672821, ECO:0000269|PubMed:15031292, ECO:0000269|PubMed:15556646, ECO:0000269|PubMed:15657060, ECO:0000269|PubMed:15886098, ECO:0000269|PubMed:16424036, ECO:0000269|PubMed:16678104, ECO:0000269|PubMed:16943190, ECO:0000269|PubMed:17306540, ECO:0000269|PubMed:17623672, ECO:0000269|PubMed:18328268, ECO:0000269|PubMed:18945674, ECO:0000269|PubMed:19891780, ECO:0000269|PubMed:20357770, ECO:0000269|PubMed:20417104, ECO:0000269|PubMed:22810897, ECO:0000269|PubMed:28428613, ECO:0000269|PubMed:9037071, ECO:0000269|PubMed:9144171, ECO:0000269|PubMed:9461559}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page * Minus value of BPloci means that the break pointn is located before the CDS.

- Retained domain in the 5'-partner of fusion protein (protein functional feature from UniProt).

106311079029029029029029029029029279279279279279279279279609601063110790290290290290290290290292792792792792792792792796096010631107

Partner	Hgeneene	Hbp	Tgeneene	Tbp	ENST	BPexon	TotalExon	Protein feature loci	BPloci	TotalLen	Feature	Note
Hgene	BCR	23654023	ABL1	133729451	ENST00000305877	18	22	893_1020	1	1228	Domain	Note=C2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00041
Hgene	BCR	23654023	ABL1	133729451	ENST00000305877	19	23	893_1020	1	1272	Domain	Note=C2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00041
Hgene	BCR	23631808	ABL1	133729449	ENST00000305877	13	22	498_691	1	1228	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23631808	ABL1	133729449	ENST00000305877	13	23	498_691	1	1272	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23631808	ABL1	133729451	ENST00000305877	13	22	498_691	1	1228	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23631808	ABL1	133729451	ENST00000305877	13	23	498_691	1	1272	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23631808	ABL1	133730188	ENST00000305877	13	22	498_691	1	1228	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23631808	ABL1	133730188	ENST00000305877	13	23	498_691	1	1272	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23631811	ABL1	133730186	ENST00000305877	13	22	498_691	1	1228	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23631811	ABL1	133730186	ENST00000305877	13	23	498_691	1	1272	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23632600	ABL1	133729450	ENST00000305877	14	22	498_691	1	1228	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23632600	ABL1	133729450	ENST00000305877	14	23	498_691	1	1272	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23632600	ABL1	133729451	ENST00000305877	14	22	498_691	1	1228	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23632600	ABL1	133729451	ENST00000305877	14	23	498_691	1	1272	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23632600	ABL1	133730188	ENST00000305877	14	22	498_691	1	1228	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23632600	ABL1	133730188	ENST00000305877	14	23	498_691	1	1272	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23632602	ABL1	133730188	ENST00000305877	14	22	498_691	1	1228	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23632602	ABL1	133730188	ENST00000305877	14	23	498_691	1	1272	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23634825	ABL1	133710453	ENST00000305877	15	22	498_691	1	1228	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23634825	ABL1	133710453	ENST00000305877	15	23	498_691	1	1272	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23654023	ABL1	133729451	ENST00000305877	18	22	498_691	1	1228	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23654023	ABL1	133729451	ENST00000305877	19	23	498_691	1	1272	Domain	Note=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Hgene	BCR	23631808	ABL1	133729449	ENST00000305877	13	22	708_866	1	1228	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23631808	ABL1	133729449	ENST00000305877	13	23	708_866	1	1272	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23631808	ABL1	133729451	ENST00000305877	13	22	708_866	1	1228	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23631808	ABL1	133729451	ENST00000305877	13	23	708_866	1	1272	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23631808	ABL1	133730188	ENST00000305877	13	22	708_866	1	1228	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23631808	ABL1	133730188	ENST00000305877	13	23	708_866	1	1272	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23631811	ABL1	133730186	ENST00000305877	13	22	708_866	1	1228	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23631811	ABL1	133730186	ENST00000305877	13	23	708_866	1	1272	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23632600	ABL1	133729450	ENST00000305877	14	22	708_866	1	1228	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23632600	ABL1	133729450	ENST00000305877	14	23	708_866	1	1272	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23632600	ABL1	133729451	ENST00000305877	14	22	708_866	1	1228	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23632600	ABL1	133729451	ENST00000305877	14	23	708_866	1	1272	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23632600	ABL1	133730188	ENST00000305877	14	22	708_866	1	1228	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23632600	ABL1	133730188	ENST00000305877	14	23	708_866	1	1272	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23632602	ABL1	133730188	ENST00000305877	14	22	708_866	1	1228	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23632602	ABL1	133730188	ENST00000305877	14	23	708_866	1	1272	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23634825	ABL1	133710453	ENST00000305877	15	22	708_866	1	1228	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23634825	ABL1	133710453	ENST00000305877	15	23	708_866	1	1272	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23654023	ABL1	133729451	ENST00000305877	18	22	708_866	1	1228	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Hgene	BCR	23654023	ABL1	133729451	ENST00000305877	19	23	708_866	1	1272	Domain	Note=PH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145

- Retained domain in the 3'-partner of fusion protein (protein functional feature from UniProt).

Partner	Hgeneene	Hbp	Tgeneene	Tbp	ENST	BPexon	TotalExon	Protein feature loci	BPloci	TotalLen	Feature	Note
Tgene	BCR	23524426	ABL1	133729448	ENST00000305877	0	11	242_493	26	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23524426	ABL1	133729450	ENST00000305877	0	11	242_493	26	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23524426	ABL1	133729451	ENST00000305877	0	11	242_493	26	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23524426	ABL1	133730188	ENST00000305877	1	11	242_493	84	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23524430	ABL1	133730185	ENST00000305877	1	11	242_493	84	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23596082	ABL1	133710840	ENST00000305877	0	11	242_493	0	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23613779	ABL1	133729451	ENST00000305877	0	11	242_493	26	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23615905	ABL1	133710870	ENST00000305877	0	11	242_493	0	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23631779	ABL1	133729451	ENST00000305877	0	11	242_493	26	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23631808	ABL1	133729449	ENST00000305877	0	11	242_493	26	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23631808	ABL1	133729451	ENST00000305877	0	11	242_493	26	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23631808	ABL1	133730188	ENST00000305877	1	11	242_493	84	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23631811	ABL1	133730186	ENST00000305877	1	11	242_493	84	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23632600	ABL1	133729450	ENST00000305877	0	11	242_493	26	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23632600	ABL1	133729451	ENST00000305877	0	11	242_493	26	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23632600	ABL1	133730188	ENST00000305877	1	11	242_493	84	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23632602	ABL1	133730188	ENST00000305877	1	11	242_493	84	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23634825	ABL1	133710453	ENST00000305877	-1	11	242_493	26	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23654023	ABL1	133729451	ENST00000305877	0	11	242_493	26	1131	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
Tgene	BCR	23524426	ABL1	133729448	ENST00000305877	0	11	127_217	26	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23524426	ABL1	133729450	ENST00000305877	0	11	127_217	26	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23524426	ABL1	133729451	ENST00000305877	0	11	127_217	26	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23524426	ABL1	133730188	ENST00000305877	1	11	127_217	84	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23524430	ABL1	133730185	ENST00000305877	1	11	127_217	84	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23596082	ABL1	133710840	ENST00000305877	0	11	127_217	0	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23613779	ABL1	133729451	ENST00000305877	0	11	127_217	26	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23615905	ABL1	133710870	ENST00000305877	0	11	127_217	0	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23631779	ABL1	133729451	ENST00000305877	0	11	127_217	26	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23631808	ABL1	133729449	ENST00000305877	0	11	127_217	26	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23631808	ABL1	133729451	ENST00000305877	0	11	127_217	26	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23631808	ABL1	133730188	ENST00000305877	1	11	127_217	84	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23631811	ABL1	133730186	ENST00000305877	1	11	127_217	84	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23632600	ABL1	133729450	ENST00000305877	0	11	127_217	26	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23632600	ABL1	133729451	ENST00000305877	0	11	127_217	26	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23632600	ABL1	133730188	ENST00000305877	1	11	127_217	84	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23632602	ABL1	133730188	ENST00000305877	1	11	127_217	84	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23634825	ABL1	133710453	ENST00000305877	-1	11	127_217	26	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23654023	ABL1	133729451	ENST00000305877	0	11	127_217	26	1131	Domain	Note=SH2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00191
Tgene	BCR	23524426	ABL1	133729448	ENST00000305877	0	11	61_121	26	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23524426	ABL1	133729450	ENST00000305877	0	11	61_121	26	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23524426	ABL1	133729451	ENST00000305877	0	11	61_121	26	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23596082	ABL1	133710840	ENST00000305877	0	11	61_121	0	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23613779	ABL1	133729451	ENST00000305877	0	11	61_121	26	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23615905	ABL1	133710870	ENST00000305877	0	11	61_121	0	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23631779	ABL1	133729451	ENST00000305877	0	11	61_121	26	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23631808	ABL1	133729449	ENST00000305877	0	11	61_121	26	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23631808	ABL1	133729451	ENST00000305877	0	11	61_121	26	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23632600	ABL1	133729450	ENST00000305877	0	11	61_121	26	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23632600	ABL1	133729451	ENST00000305877	0	11	61_121	26	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23634825	ABL1	133710453	ENST00000305877	-1	11	61_121	26	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192
Tgene	BCR	23654023	ABL1	133729451	ENST00000305877	0	11	61_121	26	1131	Domain	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192

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Kinase Fusion Protein Structures

CIF files of the predicted kinase fusion proteins * Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.

Kinase Fusion protein CIF link (fusion AA seq ID in KinaseFusionDB)	Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	AA seq	Len(AA seq)
PDB file >>>37_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23632602	ABL1	chr9	133730188	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSSEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGING SFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEM ERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL RECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFS IKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVE KELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKT NLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLW KKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTR GTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSK GPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKK PVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNS	1973
3D view using mol* of 37_BCR_ABL1
PDB file >>>HKFP_44_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23632600	ABL1	chr9	133730188	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSSEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGING SFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEM ERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL RECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFS IKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVE KELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKT NLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLW KKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTR GTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSK GPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKK PVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNS	1973_BCR_ABL1
PDB file >>>HKFP_45_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23631808	ABL1	chr9	133729451	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSN YITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST VADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIK HPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGL SRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRA CWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDH EPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTA DPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTG RQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKE EAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAG EAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRK TRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATA	2006_BCR_ABL1
3D view using mol* of HKFP_45_BCR_ABL1
PDB file >>>HKFP_46_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23631808	ABL1	chr9	133730188	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY HYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWK KYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAME YLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPG IDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKT RTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFR EMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKR FLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIM ESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKL SRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVP STLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVD	1948_BCR_ABL1
3D view using mol* of HKFP_46_BCR_ABL1
PDB file >>>HKFP_47_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23634825	ABL1	chr9	133710453	MAGPGAPGGRAGRAGPEPGPRTELGEGFRPPTCWRGKMLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKEN LLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSS GINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYD KWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNL LDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAY NKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSIS DEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPK DKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRS PHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSD QVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPG GTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGE GLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAI	1167_BCR_ABL1
3D view using mol* of HKFP_47_BCR_ABL1
PDB file >>>HKFP_48_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23632600	ABL1	chr9	133729451	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSKALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLR VLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA SDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVA VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNF IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY ELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAA EHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPE RRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSA SCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSS PPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAP PPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSAS SALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRN	2031_BCR_ABL1
3D view using mol* of HKFP_48_BCR_ABL1
PDB file >>>HKFP_49_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23632600	ABL1	chr9	133729450	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSKALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLR VLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA SDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVA VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNF IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY ELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAA EHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPE RRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSA SCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSS PPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAP PPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSAS SALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRN	2031_BCR_ABL1
PDB file >>>HKFP_50_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23654023	ABL1	chr9	133729451	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKED GESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIER RGMEEVGIYRVSGVATDIQALKAAFDVKALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLR VLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA SDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVA VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNF IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY ELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAA EHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPE RRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSA SCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSS PPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAP PPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSAS SALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRN	2211_BCR_ABL1
3D view using mol* of HKFP_50_BCR_ABL1
PDB file >>>HKFP_51_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23631808	ABL1	chr9	133729449	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSN YITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST VADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIK HPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGL SRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRA CWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDH EPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTA DPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTG RQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKE EAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAG EAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRK TRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATA	2006_BCR_ABL1
PDB file >>>HKFP_52_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23631811	ABL1	chr9	133730186	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY HYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWK KYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAME YLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPG IDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKT RTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFR EMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKR FLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIM ESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKL SRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVP STLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVD	1948_BCR_ABL1
PDB file >>>HKFP_53_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23632602	ABL1	chr9	133730188	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSSEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGING SFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEM ERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL RECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFS IKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVE KELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKT NLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLW KKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTR GTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSK GPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKK PVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNS	1973_BCR_ABL1
PDB file >>>57_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23615905	ABL1	chr9	133710870	MSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKN GQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLA ELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKE AAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHL VKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPE KVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQ GESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGAL AFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTL PRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAP ASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQ SPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLI STRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRE	1114
3D view using mol* of 57_BCR_ABL1
PDB file >>>TKFP_83_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23632600	ABL1	chr9	133730188	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSSEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGING SFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEM ERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL RECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFS IKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVE KELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKT NLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLW KKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTR GTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSK GPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKK PVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNS	1973_BCR_ABL1
PDB file >>>TKFP_84_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23596082	ABL1	chr9	133710840	MKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNH NGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY VSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKE DTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLA ARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKD YRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTT DVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGE EEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHG AKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTP KPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAA SAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGD QPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFRE	1125_BCR_ABL1
3D view using mol* of TKFP_84_BCR_ABL1
PDB file >>>TKFP_85_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23631808	ABL1	chr9	133729451	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSN YITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST VADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIK HPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGL SRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRA CWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDH EPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTA DPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTG RQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKE EAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAG EAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRK TRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATA	2006_BCR_ABL1
3D view using mol* of TKFP_85_BCR_ABL1
PDB file >>>TKFP_86_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23524426	ABL1	chr9	133730188	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDAGEKLRVLGYNHNGEWCEAQTKNGQ GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAEL VHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVK VADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKV YELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGE SDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAF TPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPR DLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPAS GLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSP SQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLIST RVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQ	1472_BCR_ABL1
3D view using mol* of TKFP_86_BCR_ABL1
PDB file >>>TKFP_87_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23631808	ABL1	chr9	133730188	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY HYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWK KYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAME YLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPG IDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKT RTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFR EMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKR FLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIM ESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKL SRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVP STLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVD	1948_BCR_ABL1
3D view using mol* of TKFP_87_BCR_ABL1
PDB file >>>TKFP_88_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23634825	ABL1	chr9	133710453	MAGPGAPGGRAGRAGPEPGPRTELGEGFRPPTCWRGKMLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKEN LLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSS GINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYD KWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNL LDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAY NKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSIS DEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPK DKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRS PHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSD QVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPG GTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGE GLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAI	1167_BCR_ABL1
3D view using mol* of TKFP_88_BCR_ABL1
PDB file >>>TKFP_89_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23524426	ABL1	chr9	133729451	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDAEALQRPVASDFEPQGLSEAARWNS KENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYL LSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSP NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTY GNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPES LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES SISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERL LPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSG FRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGEN RSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSG APGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQ PGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALC LAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR	1530_BCR_ABL1
3D view using mol* of TKFP_89_BCR_ABL1
PDB file >>>TKFP_90_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23632600	ABL1	chr9	133729451	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSKALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLR VLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA SDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVA VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNF IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY ELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAA EHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPE RRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSA SCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSS PPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAP PPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSAS SALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRN	2031_BCR_ABL1
PDB file >>>TKFP_91_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23632600	ABL1	chr9	133729450	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSKALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLR VLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA SDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVA VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNF IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY ELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAA EHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPE RRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSA SCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSS PPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAP PPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSAS SALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRN	2031_BCR_ABL1
PDB file >>>TKFP_92_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23524426	ABL1	chr9	133729450	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDAEALQRPVASDFEPQGLSEAARWNS KENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYL LSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSP NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTY GNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPES LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES SISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERL LPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSG FRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGEN RSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSG APGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQ PGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALC LAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR	1530_BCR_ABL1
PDB file >>>TKFP_93_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23524426	ABL1	chr9	133729448	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDAEALQRPVASDFEPQGLSEAARWNS KENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYL LSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSP NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTY GNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPES LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES SISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERL LPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSG FRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGEN RSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSG APGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQ PGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALC LAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR	1530_BCR_ABL1
PDB file >>>TKFP_94_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23654023	ABL1	chr9	133729451	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKED GESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIER RGMEEVGIYRVSGVATDIQALKAAFDVKALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLR VLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA SDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVA VKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNF IHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY ELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAA EHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPE RRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSA SCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSS PPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAP PPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSAS SALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRN	2211_BCR_ABL1
PDB file >>>TKFP_95_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23631808	ABL1	chr9	133729449	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSN YITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST VADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIK HPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGL SRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRA CWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDH EPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTA DPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTG RQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKE EAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAG EAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRK TRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATA	2006_BCR_ABL1
PDB file >>>TKFP_96_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23631811	ABL1	chr9	133730186	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY HYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWK KYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAME YLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPG IDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKT RTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFR EMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKR FLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIM ESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKL SRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVP STLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVD	1948_BCR_ABL1
PDB file >>>TKFP_97_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23632602	ABL1	chr9	133730188	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVE GARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKA TERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTIN KEDDESPGLYGFLNVIVHSATGFKQSSSEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGING SFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEM ERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYL RECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFS IKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVE KELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKT NLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLW KKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTR GTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSK GPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKK PVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNS	1973_BCR_ABL1
PDB file >>>TKFP_98_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23524430	ABL1	chr9	133730185	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDAGEKLRVLGYNHNGEWCEAQTKNGQ GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAEL VHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVK VADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKV YELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGE SDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAF TPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPR DLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPAS GLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSP SQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLIST RVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQ	1472_BCR_ABL1
PDB file >>>TKFP_99_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23613779	ABL1	chr9	133729451	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEP RASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNV EFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPP WPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTY RMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQ DGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTS QQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDA KDPTTKNSLEKALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKN GQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLA ELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKE AAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHL VKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPE KVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQ GESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGAL AFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTL PRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAP ASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQ SPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLI STRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRE	1744_BCR_ABL1
3D view using mol* of TKFP_99_BCR_ABL1
PDB file >>>TKFP_100_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23631779	ABL1	chr9	133729451	MTINKEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGW VPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVH HHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVA DFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYE LMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESD PLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTP LDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDL QSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGL PHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQ EAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRV SLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQIC	1110_BCR_ABL1
3D view using mol* of TKFP_100_BCR_ABL1
PDB file >>>TKFP_101_BCR_ABL1	ENST00000305877	ENST00000318560	BCR	chr22	23615905	ABL1	chr9	133710870	MSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKN GQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLA ELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKE AAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHL VKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPE KVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQ GESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGAL AFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTL PRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAP ASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQ SPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLI STRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRE	1114_BCR_ABL1
3D view using mol* of TKFP_101_BCR_ABL1

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Comparison of Fusion Protein Isoforms

Superimpose the 3D Structures Among All Fusion Protein Isoforms * Download the pdb file and open it from the molstar online viewer.

3D view using mol* of viewer/superimpose_isoforms/HKFP_44_BCR_ABL1_vs_HKFP_45_BCR_ABL1_superimposed.pdb.html

3D view using mol* of viewer/superimpose_isoforms/HKFP_44_BCR_ABL1_vs_HKFP_46_BCR_ABL1_superimposed.pdb.html

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3D view using mol* of viewer/superimpose_isoforms/HKFP_44_BCR_ABL1_vs_HKFP_48_BCR_ABL1_superimposed.pdb.html

3D view using mol* of viewer/superimpose_isoforms/HKFP_44_BCR_ABL1_vs_HKFP_50_BCR_ABL1_superimposed.pdb.html

3D view using mol* of viewer/superimpose_isoforms/HKFP_45_BCR_ABL1_vs_HKFP_46_BCR_ABL1_superimposed.pdb.html

3D view using mol* of viewer/superimpose_isoforms/HKFP_45_BCR_ABL1_vs_HKFP_47_BCR_ABL1_superimposed.pdb.html

3D view using mol* of viewer/superimpose_isoforms/HKFP_45_BCR_ABL1_vs_HKFP_48_BCR_ABL1_superimposed.pdb.html

3D view using mol* of viewer/superimpose_isoforms/HKFP_45_BCR_ABL1_vs_HKFP_50_BCR_ABL1_superimposed.pdb.html

3D view using mol* of viewer/superimpose_isoforms/HKFP_46_BCR_ABL1_vs_HKFP_47_BCR_ABL1_superimposed.pdb.html

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Comparison of the Secondary Structures of Fusion Protein Isoforms

./secondary_str/HKFP_45_BCR_ABL1_vs_HKFP_44_BCR_ABL1.png

./secondary_str/HKFP_45_BCR_ABL1_vs_HKFP_46_BCR_ABL1.png

./secondary_str/HKFP_45_BCR_ABL1_vs_HKFP_47_BCR_ABL1.png

./secondary_str/HKFP_45_BCR_ABL1_vs_HKFP_48_BCR_ABL1.png

./secondary_str/HKFP_46_BCR_ABL1_vs_HKFP_44_BCR_ABL1.png

./secondary_str/HKFP_47_BCR_ABL1_vs_HKFP_44_BCR_ABL1.png

./secondary_str/HKFP_47_BCR_ABL1_vs_HKFP_46_BCR_ABL1.png

./secondary_str/HKFP_47_BCR_ABL1_vs_HKFP_48_BCR_ABL1.png

./secondary_str/HKFP_48_BCR_ABL1_vs_HKFP_44_BCR_ABL1.png

./secondary_str/HKFP_48_BCR_ABL1_vs_HKFP_46_BCR_ABL1.png

./secondary_str/HKFP_50_BCR_ABL1_vs_HKFP_44_BCR_ABL1.png

./secondary_str/HKFP_50_BCR_ABL1_vs_HKFP_45_BCR_ABL1.png

./secondary_str/HKFP_50_BCR_ABL1_vs_HKFP_46_BCR_ABL1.png

./secondary_str/HKFP_50_BCR_ABL1_vs_HKFP_47_BCR_ABL1.png

./secondary_str/HKFP_50_BCR_ABL1_vs_HKFP_48_BCR_ABL1.png

./secondary_str/TKFP_100_BCR_ABL1_vs_TKFP_101_BCR_ABL1.png

./secondary_str/TKFP_100_BCR_ABL1_vs_TKFP_83_BCR_ABL1.png

./secondary_str/TKFP_100_BCR_ABL1_vs_TKFP_84_BCR_ABL1.png

./secondary_str/TKFP_83_BCR_ABL1_vs_TKFP_101_BCR_ABL1.png

./secondary_str/TKFP_84_BCR_ABL1_vs_TKFP_101_BCR_ABL1.png

./secondary_str/TKFP_84_BCR_ABL1_vs_TKFP_83_BCR_ABL1.png

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Comparison of Fusion Protein Sequences/Structures with Known Sequences/Structures from PDB

Abstract of the Multiple Sequence Alignment of the Longest Fusion Protein Sequence and Known Sequence from PDB Search Using Fusion Gene Names

Multiple Sequence Alignment of the Longest Fusion Protein Sequence and Known Sequence from PDB Search Using Fusion Gene Names

Superimpose the 3D Structures Between the Longest Fusion Protein and the Longest Known PDB

3D view using mol* of viewer/superimpose_pdbs/BCR_ABL1_3QRI_superimposed.pdb.html

3D view using mol* of viewer/superimpose_pdbs/BCR_ABL1_3QRJ_superimposed.pdb.html

3D view using mol* of viewer/superimpose_pdbs/BCR_ABL1_3QRK_superimposed.pdb.html

3D view using mol* of viewer/superimpose_pdbs/BCR_ABL1_4TWP_superimposed.pdb.html

3D view using mol* of viewer/superimpose_pdbs/BCR_ABL1_4WA9_superimposed.pdb.html

3D view using mol* of viewer/superimpose_pdbs/BCR_ABL1_4XEY_superimposed.pdb.html

3D view using mol* of viewer/superimpose_pdbs/BCR_ABL1_5HU9_superimposed.pdb.html

3D view using mol* of viewer/superimpose_pdbs/BCR_ABL1_5MO4_superimposed.pdb.html

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pLDDT score distribution

all_data/KinaseFusionDB_T_Results/KinaseFusionDB_T_ViolinPlots/57_BCR_ABL1.pngall_data/KinaseFusionDB_T_Results/KinaseFusionDB_T_ViolinPlots/TKFP_100_BCR_ABL1_updated_violin_plot.pngall_data/KinaseFusionDB_T_Results/KinaseFusionDB_T_ViolinPlots/TKFP_101_BCR_ABL1_updated_violin_plot.pngall_data/KinaseFusionDB_T_Results/KinaseFusionDB_T_ViolinPlots/TKFP_84_BCR_ABL1_updated_violin_plot.pngall_data/KinaseFusionDB_T_Results/KinaseFusionDB_T_ViolinPlots/TKFP_85_BCR_ABL1_updated_violin_plot.pngall_data/KinaseFusionDB_T_Results/KinaseFusionDB_T_ViolinPlots/TKFP_86_BCR_ABL1_updated_violin_plot.pngall_data/KinaseFusionDB_T_Results/KinaseFusionDB_T_ViolinPlots/TKFP_87_BCR_ABL1_updated_violin_plot.pngall_data/KinaseFusionDB_T_Results/KinaseFusionDB_T_ViolinPlots/TKFP_88_BCR_ABL1_updated_violin_plot.pngall_data/KinaseFusionDB_T_Results/KinaseFusionDB_T_ViolinPlots/TKFP_89_BCR_ABL1_updated_violin_plot.pngall_data/KinaseFusionDB_T_Results/KinaseFusionDB_T_ViolinPlots/TKFP_99_BCR_ABL1_updated_violin_plot.png

pLDDT score distribution of the predicted fusion protein structures from AlphaFold2 * AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. * The blue color at the bottom marks the best active site residues.

37_BCR_ABL1.png

37_BCR_ABL1.png

HKFP_45_BCR_ABL1.png

HKFP_46_BCR_ABL1.png

HKFP_47_BCR_ABL1.png

HKFP_48_BCR_ABL1.png

HKFP_50_BCR_ABL1.png

57_BCR_ABL1.png

57_BCR_ABL1.png

TKFP_100_BCR_ABL1.png

TKFP_101_BCR_ABL1.png

TKFP_84_BCR_ABL1.png

TKFP_85_BCR_ABL1.png

TKFP_86_BCR_ABL1.png

TKFP_87_BCR_ABL1.png

TKFP_88_BCR_ABL1.png

TKFP_89_BCR_ABL1.png

TKFP_99_BCR_ABL1.png

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Potential Active Site Information

The potential binding sites of these fusion proteins were identified using SiteMap, a module of the Schrodinger suite.

Kinase Fusion AA seq ID in KinaseFusionDB	Site score	Size	Dscore	Volume	Exposure	Enclosure	Contact	Phobic	Philic	Balance	Don/Acc	Residues
HKFP_45_BCR_ABL1	1.023	199	1.034	620.487	0.557	0.733	0.925	0.813	1.061	0.766	0.74	Chain A: 339,341,342,343,1124,1125,1127,1128,1129, 1132,1145,1147,1155,1158,1162,1166,1175,1189,1191, 1192,1193,1194,1197,1198,1238,1239,1243,1244,1246, 1256,1257,1258,1260,1262,1269,1271,1272,1274,1275, 1276,1277,1278,1279,1287,1292,1321
HKFP_46_BCR_ABL1	1.026	145	1.077	329.966	0.563	0.671	0.908	1.638	0.814	2.013	0.931	Chain A: 1150,1154,1155,1158,1159,1162,1247,1248,1 250,1251,1252,1253,1255,1277,1278,1279,1280,1281,1 282,1283,1286,1311,1320,1321,1324,1325,1327,1328,1 330,1331,1334
HKFP_47_BCR_ABL1	1.048	195	1.035	535.08	0.477	0.77	0.99	0.822	1.124	0.731	0.724	Chain A: 285,286,287,288,289,290,293,306,307,308,3 19,323,327,336,350,352,353,354,355,358,359,398,399 ,400,404,405,407,417,418,419,420,421,422,423,430,4 32,433,436,437,438,439,453
HKFP_48_BCR_ABL1	1.031	185	1.038	805.364	0.646	0.745	0.868	0.302	1.069	0.282	0.62	Chain A: 970,971,1024,1029,1030,1033,1034,1035,103 6,1037,1040,1041,1053,1054,1055,1056,1057,1061,106 2,1063,1074,1076,1120,1121,1122,1123,1124,1125,119 7,1198,1243,1246,1247,1250,1275,1277,1279,1391,139 2,1395,1396,1399
HKFP_50_BCR_ABL1	1.098	127	1.159	430.122	0.535	0.746	0.913	1.482	0.701	2.115	0.375	Chain A: 595,596,598,599,600,602,644,647,648,650,6 51,654,655,682,684,685,686,688,689,692,695,696,179 5,1797,1798,1799,1800,1801
TKFP_84_BCR_ABL1	1.045	228	1.029	694.575	0.505	0.766	0.971	0.673	1.138	0.591	0.778	Chain A: 242,243,244,245,246,247,248,251,264,266,2 77,281,285,294,308,310,311,312,313,316,317,356,357 ,358,362,363,365,375,376,377,378,379,380,381,388,3 90,391,394,395,396,397,398,399,400,411,440,608,609 ,612
TKFP_100_BCR_ABL1	1.047	196	1.019	528.22	0.479	0.768	1.003	0.745	1.171	0.636	0.843	Chain A: 228,229,230,231,232,233,234,236,249,251,2 62,266,270,279,293,295,296,297,298,301,302,341,342 ,343,347,348,350,360,361,362,363,364,365,366,373,3 75,376,379,380,381,382,396
TKFP_101_BCR_ABL1	1.046	206	1.041	592.361	0.515	0.767	0.969	0.74	1.101	0.672	0.754	Chain A: 232,233,234,235,236,237,238,240,253,255,2 62,263,266,270,274,283,297,299,300,301,302,305,306 ,346,347,351,352,354,364,365,366,367,368,369,370,3 77,379,380,383,384,385,386,400
TKFP_85_BCR_ABL1	1.09	124	1.128	344.029	0.563	0.781	1.074	1.205	0.86	1.401	0.936	Chain A: 506,509,510,512,513,515,516,518,519,522,5 57,560,581,584,585,588,591,622,625,626,627,637,642 ,645,648,649,650,652,653,656,657,677,681
TKFP_86_BCR_ABL1	1.093	132	1.178	466.137	0.542	0.697	0.977	1.66	0.552	3.009	0.682	Chain A: 51,54,55,57,58,61,62,64,65,68,176,177,178 ,179,180,181,182,184,189,191,193,196,199,200,203,2 06,207,210
TKFP_87_BCR_ABL1	1.04	136	1.096	289.835	0.571	0.679	0.895	1.76	0.77	2.284	1.116	Chain A: 1150,1154,1155,1158,1159,1162,1247,1248,1 250,1251,1252,1253,1255,1258,1259,1261,1274,1276,1 277,1279,1280,1281,1282,1283,1286,1311,1320,1321,1 324,1325,1328
TKFP_88_BCR_ABL1	1.108	106	1.162	225.008	0.462	0.774	1.079	2.801	0.744	3.764	1.328	Chain A: 369,373,374,377,378,381,466,469,470,471,4 72,474,498,499,500,501,502,505,530,539,540,543,547
TKFP_89_BCR_ABL1	1.058	176	1.035	538.167	0.497	0.785	0.999	0.856	1.153	0.742	0.763	Chain A: 648,649,650,651,652,653,656,669,671,682,6 86,690,699,713,715,716,717,718,721,722,725,761,762 ,763,767,768,770,780,781,782,783,784,785,786,793,7 95,796,799,800,801,802,816
TKFP_99_BCR_ABL1	1.06	164	1.045	526.162	0.502	0.787	1.03	0.976	1.128	0.865	0.748	Chain A: 862,863,865,866,867,870,883,885,893,896,9 00,904,913,927,929,930,931,932,935,936,976,977,982 ,984,994,995,996,997,998,999,1000,1007,1009,1010,1 013,1014,1015,1016

Binding site residues of the found PDBs.

PDB accession	AA sequence	Residue position
3QRI	SER	224
3QRI	MET	225
3QRI	ASP	226
3QRI	PRO	227
3QRI	SER	228
3QRI	SER	229
3QRI	PRO	230
3QRI	ASN	231
3QRI	TYR	232
3QRI	ASP	233
3QRI	LYS	234
3QRI	TRP	235
3QRI	GLU	236
3QRI	MET	237
3QRI	GLU	238
3QRI	ARG	239
3QRI	THR	240
3QRI	ASP	241
3QRI	ILE	242
3QRI	THR	243
3QRI	MET	244
3QRI	LYS	245
3QRI	HIS	246
3QRI	LYS	247
3QRI	LEU	248
3QRI	GLY	249
3QRI	GLY	250
3QRI	GLY	251
3QRI	GLN	252
3QRI	TYR	253
3QRI	GLY	254
3QRI	GLU	255
3QRI	VAL	256
3QRI	TYR	257
3QRI	GLU	258
3QRI	GLY	259
3QRI	VAL	260
3QRI	TRP	261
3QRI	LYS	262
3QRI	LYS	263
3QRI	TYR	264
3QRI	SER	265
3QRI	LEU	266
3QRI	THR	267
3QRI	VAL	268
3QRI	ALA	269
3QRI	VAL	270
3QRI	LYS	271
3QRI	THR	272
3QRI	LEU	273
3QRI	LYS	274
3QRI	GLU	275
3QRI	ASP	276
3QRI	THR	277
3QRI	MET	278
3QRI	GLU	279
3QRI	VAL	280
3QRI	GLU	281
3QRI	GLU	282
3QRI	PHE	283
3QRI	LEU	284
3QRI	LYS	285
3QRI	GLU	286
3QRI	ALA	287
3QRI	ALA	288
3QRI	VAL	289
3QRI	MET	290
3QRI	LYS	291
3QRI	GLU	292
3QRI	ILE	293
3QRI	LYS	294
3QRI	HIS	295
3QRI	PRO	296
3QRI	ASN	297
3QRI	LEU	298
3QRI	VAL	299
3QRI	GLN	300
3QRI	LEU	301
3QRI	LEU	302
3QRI	GLY	303
3QRI	VAL	304
3QRI	CYS	305
3QRI	THR	306
3QRI	ARG	307
3QRI	GLU	308
3QRI	PRO	309
3QRI	PRO	310
3QRI	PHE	311
3QRI	TYR	312
3QRI	ILE	313
3QRI	ILE	314
3QRI	THR	315
3QRI	GLU	316
3QRI	PHE	317
3QRI	MET	318
3QRI	THR	319
3QRI	TYR	320
3QRI	GLY	321
3QRI	ASN	322
3QRI	LEU	323
3QRI	LEU	324
3QRI	ASP	325
3QRI	TYR	326
3QRI	LEU	327
3QRI	ARG	328
3QRI	GLU	329
3QRI	CYS	330
3QRI	ASN	331
3QRI	ARG	332
3QRI	GLN	333
3QRI	GLU	334
3QRI	VAL	335
3QRI	ASN	336
3QRI	ALA	337
3QRI	VAL	338
3QRI	VAL	339
3QRI	LEU	340
3QRI	LEU	341
3QRI	TYR	342
3QRI	MET	343
3QRI	ALA	344
3QRI	THR	345
3QRI	GLN	346
3QRI	ILE	347
3QRI	SER	348
3QRI	SER	349
3QRI	ALA	350
3QRI	MET	351
3QRI	GLU	352
3QRI	TYR	353
3QRI	LEU	354
3QRI	GLU	355
3QRI	LYS	356
3QRI	LYS	357
3QRI	ASN	358
3QRI	PHE	359
3QRI	ILE	360
3QRI	HIS	361
3QRI	ARG	362
3QRI	ASP	363
3QRI	LEU	364
3QRI	ALA	365
3QRI	ALA	366
3QRI	ARG	367
3QRI	ASN	368
3QRI	CYS	369
3QRI	LEU	370
3QRI	VAL	371
3QRI	GLY	372
3QRI	GLU	373
3QRI	ASN	374
3QRI	HIS	375
3QRI	LEU	376
3QRI	VAL	377
3QRI	LYS	378
3QRI	VAL	379
3QRI	ALA	380
3QRI	ASP	381
3QRI	PHE	382
3QRI	GLY	383
3QRI	LEU	384
3QRI	SER	385
3QRI	ARG	386
3QRI	LEU	387
3QRI	MET	388
3QRI	THR	389
3QRI	GLY	390
3QRI	ASP	391
3QRI	THR	392
3QRI	TYR	393
3QRI	THR	394
3QRI	ALA	395
3QRI	HIS	396
3QRI	ALA	397
3QRI	GLY	398
3QRI	ALA	399
3QRI	LYS	400
3QRI	PHE	401
3QRI	PRO	402
3QRI	ILE	403
3QRI	LYS	404
3QRI	TRP	405
3QRI	THR	406
3QRI	ALA	407
3QRI	PRO	408
3QRI	GLU	409
3QRI	SER	410
3QRI	LEU	411
3QRI	ALA	412
3QRI	TYR	413
3QRI	ASN	414
3QRI	LYS	415
3QRI	PHE	416
3QRI	SER	417
3QRI	ILE	418
3QRI	LYS	419
3QRI	SER	420
3QRI	ASP	421
3QRI	VAL	422
3QRI	TRP	423
3QRI	ALA	424
3QRI	PHE	425
3QRI	GLY	426
3QRI	VAL	427
3QRI	LEU	428
3QRI	LEU	429
3QRI	TRP	430
3QRI	GLU	431
3QRI	ILE	432
3QRI	ALA	433
3QRI	THR	434
3QRI	TYR	435
3QRI	GLY	436
3QRI	MET	437
3QRI	SER	438
3QRI	PRO	439
3QRI	TYR	440
3QRI	PRO	441
3QRI	GLY	442
3QRI	ILE	443
3QRI	ASP	444
3QRI	LEU	445
3QRI	SER	446
3QRI	GLN	447
3QRI	VAL	448
3QRI	TYR	449
3QRI	GLU	450
3QRI	LEU	451
3QRI	LEU	452
3QRI	GLU	453
3QRI	LYS	454
3QRI	ASP	455
3QRI	TYR	456
3QRI	ARG	457
3QRI	MET	458
3QRI	GLU	459
3QRI	ARG	460
3QRI	PRO	461
3QRI	GLU	462
3QRI	GLY	463
3QRI	CYS	464
3QRI	PRO	465
3QRI	GLU	466
3QRI	LYS	467
3QRI	VAL	468
3QRI	TYR	469
3QRI	GLU	470
3QRI	LEU	471
3QRI	MET	472
3QRI	ARG	473
3QRI	ALA	474
3QRI	CYS	475
3QRI	TRP	476
3QRI	GLN	477
3QRI	TRP	478
3QRI	ASN	479
3QRI	PRO	480
3QRI	SER	481
3QRI	ASP	482
3QRI	ARG	483
3QRI	PRO	484
3QRI	SER	485
3QRI	PHE	486
3QRI	ALA	487
3QRI	GLU	488
3QRI	ILE	489
3QRI	HIS	490
3QRI	GLN	491
3QRI	ALA	492
3QRI	PHE	493
3QRI	GLU	494
3QRI	THR	495
3QRI	MET	496
3QRI	PHE	497
3QRI	GLN	498
3QRI	TYR	232
3QRI	ASP	233
3QRI	LYS	234
3QRI	TRP	235
3QRI	GLU	236
3QRI	MET	237
3QRI	GLU	238
3QRI	ARG	239
3QRI	THR	240
3QRI	ASP	241
3QRI	ILE	242
3QRI	THR	243
3QRI	MET	244
3QRI	LYS	245
3QRI	HIS	246
3QRI	LYS	247
3QRI	LEU	248
3QRI	GLY	249
3QRI	GLY	250
3QRI	GLY	251
3QRI	GLN	252
3QRI	TYR	253
3QRI	GLY	254
3QRI	GLU	255
3QRI	VAL	256
3QRI	TYR	257
3QRI	GLU	258
3QRI	GLY	259
3QRI	VAL	260
3QRI	TRP	261
3QRI	LYS	262
3QRI	LYS	263
3QRI	TYR	264
3QRI	SER	265
3QRI	LEU	266
3QRI	THR	267
3QRI	VAL	268
3QRI	ALA	269
3QRI	VAL	270
3QRI	LYS	271
3QRI	THR	272
3QRI	LEU	273
3QRI	GLU	279
3QRI	VAL	280
3QRI	GLU	281
3QRI	GLU	282
3QRI	PHE	283
3QRI	LEU	284
3QRI	LYS	285
3QRI	GLU	286
3QRI	ALA	287
3QRI	ALA	288
3QRI	VAL	289
3QRI	MET	290
3QRI	LYS	291
3QRI	GLU	292
3QRI	ILE	293
3QRI	LYS	294
3QRI	HIS	295
3QRI	PRO	296
3QRI	ASN	297
3QRI	LEU	298
3QRI	VAL	299
3QRI	GLN	300
3QRI	LEU	301
3QRI	LEU	302
3QRI	GLY	303
3QRI	VAL	304
3QRI	CYS	305
3QRI	THR	306
3QRI	ARG	307
3QRI	GLU	308
3QRI	PRO	309
3QRI	PRO	310
3QRI	PHE	311
3QRI	TYR	312
3QRI	ILE	313
3QRI	ILE	314
3QRI	THR	315
3QRI	GLU	316
3QRI	PHE	317
3QRI	MET	318
3QRI	THR	319
3QRI	TYR	320
3QRI	GLY	321
3QRI	ASN	322
3QRI	LEU	323
3QRI	LEU	324
3QRI	ASP	325
3QRI	TYR	326
3QRI	LEU	327
3QRI	ARG	328
3QRI	GLU	329
3QRI	CYS	330
3QRI	ASN	331
3QRI	ARG	332
3QRI	GLN	333
3QRI	GLU	334
3QRI	VAL	335
3QRI	ASN	336
3QRI	ALA	337
3QRI	VAL	338
3QRI	VAL	339
3QRI	LEU	340
3QRI	LEU	341
3QRI	TYR	342
3QRI	MET	343
3QRI	ALA	344
3QRI	THR	345
3QRI	GLN	346
3QRI	ILE	347
3QRI	SER	348
3QRI	SER	349
3QRI	ALA	350
3QRI	MET	351
3QRI	GLU	352
3QRI	TYR	353
3QRI	LEU	354
3QRI	GLU	355
3QRI	LYS	356
3QRI	LYS	357
3QRI	ASN	358
3QRI	PHE	359
3QRI	ILE	360
3QRI	HIS	361
3QRI	ARG	362
3QRI	ASP	363
3QRI	LEU	364
3QRI	ALA	365
3QRI	ALA	366
3QRI	ARG	367
3QRI	ASN	368
3QRI	CYS	369
3QRI	LEU	370
3QRI	VAL	371
3QRI	GLY	372
3QRI	GLU	373
3QRI	ASN	374
3QRI	HIS	375
3QRI	LEU	376
3QRI	VAL	377
3QRI	LYS	378
3QRI	VAL	379
3QRI	ALA	380
3QRI	ASP	381
3QRI	PHE	382
3QRI	GLY	383
3QRI	LEU	384
3QRI	SER	385
3QRI	ARG	386
3QRI	LEU	387
3QRI	MET	388
3QRI	THR	389
3QRI	GLY	390
3QRI	ASP	391
3QRI	THR	392
3QRI	TYR	393
3QRI	THR	394
3QRI	ALA	395
3QRI	HIS	396
3QRI	ALA	397
3QRI	GLY	398
3QRI	ALA	399
3QRI	LYS	400
3QRI	PHE	401
3QRI	PRO	402
3QRI	ILE	403
3QRI	LYS	404
3QRI	TRP	405
3QRI	THR	406
3QRI	ALA	407
3QRI	PRO	408
3QRI	GLU	409
3QRI	SER	410
3QRI	LEU	411
3QRI	ALA	412
3QRI	TYR	413
3QRI	ASN	414
3QRI	LYS	415
3QRI	PHE	416
3QRI	SER	417
3QRI	ILE	418
3QRI	LYS	419
3QRI	SER	420
3QRI	ASP	421
3QRI	VAL	422
3QRI	TRP	423
3QRI	ALA	424
3QRI	PHE	425
3QRI	GLY	426
3QRI	VAL	427
3QRI	LEU	428
3QRI	LEU	429
3QRI	TRP	430
3QRI	GLU	431
3QRI	ILE	432
3QRI	ALA	433
3QRI	THR	434
3QRI	TYR	435
3QRI	GLY	436
3QRI	MET	437
3QRI	SER	438
3QRI	PRO	439
3QRI	TYR	440
3QRI	PRO	441
3QRI	GLY	442
3QRI	ILE	443
3QRI	ASP	444
3QRI	LEU	445
3QRI	SER	446
3QRI	GLN	447
3QRI	VAL	448
3QRI	TYR	449
3QRI	GLU	450
3QRI	LEU	451
3QRI	LEU	452
3QRI	GLU	453
3QRI	LYS	454
3QRI	ASP	455
3QRI	TYR	456
3QRI	ARG	457
3QRI	MET	458
3QRI	GLU	459
3QRI	ARG	460
3QRI	PRO	461
3QRI	GLU	462
3QRI	GLY	463
3QRI	CYS	464
3QRI	PRO	465
3QRI	GLU	466
3QRI	LYS	467
3QRI	VAL	468
3QRI	TYR	469
3QRI	GLU	470
3QRI	LEU	471
3QRI	MET	472
3QRI	ARG	473
3QRI	ALA	474
3QRI	CYS	475
3QRI	TRP	476
3QRI	GLN	477
3QRI	TRP	478
3QRI	ASN	479
3QRI	PRO	480
3QRI	SER	481
3QRI	ASP	482
3QRI	ARG	483
3QRI	PRO	484
3QRI	SER	485
3QRI	PHE	486
3QRI	ALA	487
3QRI	GLU	488
3QRI	ILE	489
3QRI	HIS	490
3QRI	GLN	491
3QRI	ALA	492
3QRI	PHE	493
3QRI	GLU	494
3QRI	THR	495
3QRI	MET	496
3QRI	PHE	497
3QRI	GLN	498
3QRJ	LYS	234
3QRJ	TRP	235
3QRJ	GLU	236
3QRJ	MET	237
3QRJ	GLU	238
3QRJ	ARG	239
3QRJ	THR	240
3QRJ	ASP	241
3QRJ	ILE	242
3QRJ	THR	243
3QRJ	MET	244
3QRJ	LYS	245
3QRJ	HIS	246
3QRJ	LYS	247
3QRJ	LEU	248
3QRJ	GLY	249
3QRJ	GLY	250
3QRJ	GLY	251
3QRJ	GLN	252
3QRJ	TYR	253
3QRJ	GLY	254
3QRJ	GLU	255
3QRJ	VAL	256
3QRJ	TYR	257
3QRJ	GLU	258
3QRJ	GLY	259
3QRJ	VAL	260
3QRJ	TRP	261
3QRJ	LYS	262
3QRJ	LYS	263
3QRJ	TYR	264
3QRJ	SER	265
3QRJ	LEU	266
3QRJ	THR	267
3QRJ	VAL	268
3QRJ	ALA	269
3QRJ	VAL	270
3QRJ	LYS	271
3QRJ	THR	272
3QRJ	LEU	273
3QRJ	GLU	279
3QRJ	VAL	280
3QRJ	GLU	281
3QRJ	GLU	282
3QRJ	PHE	283
3QRJ	LEU	284
3QRJ	LYS	285
3QRJ	GLU	286
3QRJ	ALA	287
3QRJ	ALA	288
3QRJ	VAL	289
3QRJ	MET	290
3QRJ	LYS	291
3QRJ	GLU	292
3QRJ	ILE	293
3QRJ	LYS	294
3QRJ	HIS	295
3QRJ	PRO	296
3QRJ	ASN	297
3QRJ	LEU	298
3QRJ	VAL	299
3QRJ	GLN	300
3QRJ	LEU	301
3QRJ	LEU	302
3QRJ	GLY	303
3QRJ	VAL	304
3QRJ	CYS	305
3QRJ	THR	306
3QRJ	ARG	307
3QRJ	GLU	308
3QRJ	PRO	309
3QRJ	PRO	310
3QRJ	PHE	311
3QRJ	TYR	312
3QRJ	ILE	313
3QRJ	ILE	314
3QRJ	ILE	315
3QRJ	GLU	316
3QRJ	PHE	317
3QRJ	MET	318
3QRJ	THR	319
3QRJ	TYR	320
3QRJ	GLY	321
3QRJ	ASN	322
3QRJ	LEU	323
3QRJ	LEU	324
3QRJ	ASP	325
3QRJ	TYR	326
3QRJ	LEU	327
3QRJ	ARG	328
3QRJ	GLU	329
3QRJ	CYS	330
3QRJ	ASN	331
3QRJ	ARG	332
3QRJ	GLN	333
3QRJ	GLU	334
3QRJ	VAL	335
3QRJ	ASN	336
3QRJ	ALA	337
3QRJ	VAL	338
3QRJ	VAL	339
3QRJ	LEU	340
3QRJ	LEU	341
3QRJ	TYR	342
3QRJ	MET	343
3QRJ	ALA	344
3QRJ	THR	345
3QRJ	GLN	346
3QRJ	ILE	347
3QRJ	SER	348
3QRJ	SER	349
3QRJ	ALA	350
3QRJ	MET	351
3QRJ	GLU	352
3QRJ	TYR	353
3QRJ	LEU	354
3QRJ	GLU	355
3QRJ	LYS	356
3QRJ	LYS	357
3QRJ	ASN	358
3QRJ	PHE	359
3QRJ	ILE	360
3QRJ	HIS	361
3QRJ	ARG	362
3QRJ	ASP	363
3QRJ	LEU	364
3QRJ	ALA	365
3QRJ	ALA	366
3QRJ	ARG	367
3QRJ	ASN	368
3QRJ	CYS	369
3QRJ	LEU	370
3QRJ	VAL	371
3QRJ	GLY	372
3QRJ	GLU	373
3QRJ	ASN	374
3QRJ	HIS	375
3QRJ	LEU	376
3QRJ	VAL	377
3QRJ	LYS	378
3QRJ	VAL	379
3QRJ	ALA	380
3QRJ	ASP	381
3QRJ	PHE	382
3QRJ	GLY	383
3QRJ	LEU	384
3QRJ	SER	385
3QRJ	ARG	386
3QRJ	LEU	387
3QRJ	MET	388
3QRJ	THR	389
3QRJ	GLY	390
3QRJ	ASP	391
3QRJ	THR	392
3QRJ	TYR	393
3QRJ	THR	394
3QRJ	ALA	395
3QRJ	HIS	396
3QRJ	ALA	397
3QRJ	GLY	398
3QRJ	ALA	399
3QRJ	LYS	400
3QRJ	PHE	401
3QRJ	PRO	402
3QRJ	ILE	403
3QRJ	LYS	404
3QRJ	TRP	405
3QRJ	THR	406
3QRJ	ALA	407
3QRJ	PRO	408
3QRJ	GLU	409
3QRJ	SER	410
3QRJ	LEU	411
3QRJ	ALA	412
3QRJ	TYR	413
3QRJ	ASN	414
3QRJ	LYS	415
3QRJ	PHE	416
3QRJ	SER	417
3QRJ	ILE	418
3QRJ	LYS	419
3QRJ	SER	420
3QRJ	ASP	421
3QRJ	VAL	422
3QRJ	TRP	423
3QRJ	ALA	424
3QRJ	PHE	425
3QRJ	GLY	426
3QRJ	VAL	427
3QRJ	LEU	428
3QRJ	LEU	429
3QRJ	TRP	430
3QRJ	GLU	431
3QRJ	ILE	432
3QRJ	ALA	433
3QRJ	THR	434
3QRJ	TYR	435
3QRJ	GLY	436
3QRJ	MET	437
3QRJ	SER	438
3QRJ	PRO	439
3QRJ	TYR	440
3QRJ	PRO	441
3QRJ	GLY	442
3QRJ	ILE	443
3QRJ	ASP	444
3QRJ	LEU	445
3QRJ	SER	446
3QRJ	GLN	447
3QRJ	VAL	448
3QRJ	TYR	449
3QRJ	GLU	450
3QRJ	LEU	451
3QRJ	LEU	452
3QRJ	GLU	453
3QRJ	LYS	454
3QRJ	ASP	455
3QRJ	TYR	456
3QRJ	ARG	457
3QRJ	MET	458
3QRJ	GLU	459
3QRJ	ARG	460
3QRJ	PRO	461
3QRJ	GLU	462
3QRJ	GLY	463
3QRJ	CYS	464
3QRJ	PRO	465
3QRJ	GLU	466
3QRJ	LYS	467
3QRJ	VAL	468
3QRJ	TYR	469
3QRJ	GLU	470
3QRJ	LEU	471
3QRJ	MET	472
3QRJ	ARG	473
3QRJ	ALA	474
3QRJ	CYS	475
3QRJ	TRP	476
3QRJ	GLN	477
3QRJ	TRP	478
3QRJ	ASN	479
3QRJ	PRO	480
3QRJ	SER	481
3QRJ	ASP	482
3QRJ	ARG	483
3QRJ	PRO	484
3QRJ	SER	485
3QRJ	PHE	486
3QRJ	ALA	487
3QRJ	GLU	488
3QRJ	ILE	489
3QRJ	HIS	490
3QRJ	GLN	491
3QRJ	ALA	492
3QRJ	PHE	493
3QRJ	GLU	494
3QRJ	THR	495
3QRJ	MET	496
3QRJ	ASP	233
3QRJ	LYS	234
3QRJ	TRP	235
3QRJ	GLU	236
3QRJ	MET	237
3QRJ	GLU	238
3QRJ	ARG	239
3QRJ	THR	240
3QRJ	ASP	241
3QRJ	ILE	242
3QRJ	THR	243
3QRJ	MET	244
3QRJ	LYS	245
3QRJ	HIS	246
3QRJ	LYS	247
3QRJ	LEU	248
3QRJ	GLY	249
3QRJ	GLY	250
3QRJ	GLY	251
3QRJ	GLN	252
3QRJ	TYR	253
3QRJ	GLY	254
3QRJ	GLU	255
3QRJ	VAL	256
3QRJ	TYR	257
3QRJ	GLU	258
3QRJ	GLY	259
3QRJ	VAL	260
3QRJ	TRP	261
3QRJ	LYS	262
3QRJ	LYS	263
3QRJ	TYR	264
3QRJ	SER	265
3QRJ	LEU	266
3QRJ	THR	267
3QRJ	VAL	268
3QRJ	ALA	269
3QRJ	VAL	270
3QRJ	LYS	271
3QRJ	THR	272
3QRJ	LEU	273
3QRJ	LYS	274
3QRJ	GLU	275
3QRJ	ASP	276
3QRJ	THR	277
3QRJ	MET	278
3QRJ	GLU	279
3QRJ	VAL	280
3QRJ	GLU	281
3QRJ	GLU	282
3QRJ	PHE	283
3QRJ	LEU	284
3QRJ	LYS	285
3QRJ	GLU	286
3QRJ	ALA	287
3QRJ	ALA	288
3QRJ	VAL	289
3QRJ	MET	290
3QRJ	LYS	291
3QRJ	GLU	292
3QRJ	ILE	293
3QRJ	LYS	294
3QRJ	HIS	295
3QRJ	PRO	296
3QRJ	ASN	297
3QRJ	LEU	298
3QRJ	VAL	299
3QRJ	GLN	300
3QRJ	LEU	301
3QRJ	LEU	302
3QRJ	GLY	303
3QRJ	VAL	304
3QRJ	CYS	305
3QRJ	THR	306
3QRJ	ARG	307
3QRJ	GLU	308
3QRJ	PRO	309
3QRJ	PRO	310
3QRJ	PHE	311
3QRJ	TYR	312
3QRJ	ILE	313
3QRJ	ILE	314
3QRJ	ILE	315
3QRJ	GLU	316
3QRJ	PHE	317
3QRJ	MET	318
3QRJ	THR	319
3QRJ	TYR	320
3QRJ	GLY	321
3QRJ	ASN	322
3QRJ	LEU	323
3QRJ	LEU	324
3QRJ	ASP	325
3QRJ	TYR	326
3QRJ	LEU	327
3QRJ	ARG	328
3QRJ	GLU	329
3QRJ	CYS	330
3QRJ	ASN	331
3QRJ	ARG	332
3QRJ	GLN	333
3QRJ	GLU	334
3QRJ	VAL	335
3QRJ	ASN	336
3QRJ	ALA	337
3QRJ	VAL	338
3QRJ	VAL	339
3QRJ	LEU	340
3QRJ	LEU	341
3QRJ	TYR	342
3QRJ	MET	343
3QRJ	ALA	344
3QRJ	THR	345
3QRJ	GLN	346
3QRJ	ILE	347
3QRJ	SER	348
3QRJ	SER	349
3QRJ	ALA	350
3QRJ	MET	351
3QRJ	GLU	352
3QRJ	TYR	353
3QRJ	LEU	354
3QRJ	GLU	355
3QRJ	LYS	356
3QRJ	LYS	357
3QRJ	ASN	358
3QRJ	PHE	359
3QRJ	ILE	360
3QRJ	HIS	361
3QRJ	ARG	362
3QRJ	ASP	363
3QRJ	LEU	364
3QRJ	ALA	365
3QRJ	ALA	366
3QRJ	ARG	367
3QRJ	ASN	368
3QRJ	CYS	369
3QRJ	LEU	370
3QRJ	VAL	371
3QRJ	GLY	372
3QRJ	GLU	373
3QRJ	ASN	374
3QRJ	HIS	375
3QRJ	LEU	376
3QRJ	VAL	377
3QRJ	LYS	378
3QRJ	VAL	379
3QRJ	ALA	380
3QRJ	ASP	381
3QRJ	PHE	382
3QRJ	GLY	383
3QRJ	LEU	384
3QRJ	SER	385
3QRJ	ARG	386
3QRJ	LEU	387
3QRJ	MET	388
3QRJ	THR	389
3QRJ	GLY	390
3QRJ	ASP	391
3QRJ	THR	392
3QRJ	TYR	393
3QRJ	THR	394
3QRJ	ALA	395
3QRJ	HIS	396
3QRJ	ALA	397
3QRJ	GLY	398
3QRJ	ALA	399
3QRJ	LYS	400
3QRJ	PHE	401
3QRJ	PRO	402
3QRJ	ILE	403
3QRJ	LYS	404
3QRJ	TRP	405
3QRJ	THR	406
3QRJ	ALA	407
3QRJ	PRO	408
3QRJ	GLU	409
3QRJ	SER	410
3QRJ	LEU	411
3QRJ	ALA	412
3QRJ	TYR	413
3QRJ	ASN	414
3QRJ	LYS	415
3QRJ	PHE	416
3QRJ	SER	417
3QRJ	ILE	418
3QRJ	LYS	419
3QRJ	SER	420
3QRJ	ASP	421
3QRJ	VAL	422
3QRJ	TRP	423
3QRJ	ALA	424
3QRJ	PHE	425
3QRJ	GLY	426
3QRJ	VAL	427
3QRJ	LEU	428
3QRJ	LEU	429
3QRJ	TRP	430
3QRJ	GLU	431
3QRJ	ILE	432
3QRJ	ALA	433
3QRJ	THR	434
3QRJ	TYR	435
3QRJ	GLY	436
3QRJ	MET	437
3QRJ	SER	438
3QRJ	PRO	439
3QRJ	TYR	440
3QRJ	PRO	441
3QRJ	GLY	442
3QRJ	ILE	443
3QRJ	ASP	444
3QRJ	LEU	445
3QRJ	SER	446
3QRJ	GLN	447
3QRJ	VAL	448
3QRJ	TYR	449
3QRJ	GLU	450
3QRJ	LEU	451
3QRJ	LEU	452
3QRJ	GLU	453
3QRJ	LYS	454
3QRJ	ASP	455
3QRJ	TYR	456
3QRJ	ARG	457
3QRJ	MET	458
3QRJ	GLU	459
3QRJ	ARG	460
3QRJ	PRO	461
3QRJ	GLU	462
3QRJ	GLY	463
3QRJ	CYS	464
3QRJ	PRO	465
3QRJ	GLU	466
3QRJ	LYS	467
3QRJ	VAL	468
3QRJ	TYR	469
3QRJ	GLU	470
3QRJ	LEU	471
3QRJ	MET	472
3QRJ	ARG	473
3QRJ	ALA	474
3QRJ	CYS	475
3QRJ	TRP	476
3QRJ	GLN	477
3QRJ	TRP	478
3QRJ	ASN	479
3QRJ	PRO	480
3QRJ	SER	481
3QRJ	ASP	482
3QRJ	ARG	483
3QRJ	PRO	484
3QRJ	SER	485
3QRJ	PHE	486
3QRJ	ALA	487
3QRJ	GLU	488
3QRJ	ILE	489
3QRJ	HIS	490
3QRJ	GLN	491
3QRJ	ALA	492
3QRJ	PHE	493
3QRJ	GLU	494
3QRJ	THR	495
3QRJ	MET	496
3QRJ	PHE	497
3QRK	PRO	227
3QRK	SER	228
3QRK	SER	229
3QRK	PRO	230
3QRK	ASN	231
3QRK	TYR	232
3QRK	ASP	233
3QRK	LYS	234
3QRK	TRP	235
3QRK	GLU	236
3QRK	MET	237
3QRK	GLU	238
3QRK	ARG	239
3QRK	THR	240
3QRK	ASP	241
3QRK	ILE	242
3QRK	THR	243
3QRK	MET	244
3QRK	LYS	245
3QRK	HIS	246
3QRK	LYS	247
3QRK	LEU	248
3QRK	GLY	249
3QRK	GLY	250
3QRK	GLY	251
3QRK	GLN	252
3QRK	TYR	253
3QRK	GLY	254
3QRK	GLU	255
3QRK	VAL	256
3QRK	TYR	257
3QRK	GLU	258
3QRK	GLY	259
3QRK	VAL	260
3QRK	TRP	261
3QRK	LYS	262
3QRK	LYS	263
3QRK	TYR	264
3QRK	SER	265
3QRK	LEU	266
3QRK	THR	267
3QRK	VAL	268
3QRK	ALA	269
3QRK	VAL	270
3QRK	LYS	271
3QRK	THR	272
3QRK	LEU	273
3QRK	LYS	274
3QRK	GLU	275
3QRK	ASP	276
3QRK	THR	277
3QRK	MET	278
3QRK	GLU	279
3QRK	VAL	280
3QRK	GLU	281
3QRK	GLU	282
3QRK	PHE	283
3QRK	LEU	284
3QRK	LYS	285
3QRK	GLU	286
3QRK	ALA	287
3QRK	ALA	288
3QRK	VAL	289
3QRK	MET	290
3QRK	LYS	291
3QRK	GLU	292
3QRK	ILE	293
3QRK	LYS	294
3QRK	HIS	295
3QRK	PRO	296
3QRK	ASN	297
3QRK	LEU	298
3QRK	VAL	299
3QRK	GLN	300
3QRK	LEU	301
3QRK	LEU	302
3QRK	GLY	303
3QRK	VAL	304
3QRK	CYS	305
3QRK	THR	306
3QRK	ARG	307
3QRK	GLU	308
3QRK	PRO	309
3QRK	PRO	310
3QRK	PHE	311
3QRK	TYR	312
3QRK	ILE	313
3QRK	ILE	314
3QRK	THR	315
3QRK	GLU	316
3QRK	PHE	317
3QRK	MET	318
3QRK	THR	319
3QRK	TYR	320
3QRK	GLY	321
3QRK	ASN	322
3QRK	LEU	323
3QRK	LEU	324
3QRK	ASP	325
3QRK	TYR	326
3QRK	LEU	327
3QRK	ARG	328
3QRK	GLU	329
3QRK	CYS	330
3QRK	ASN	331
3QRK	ARG	332
3QRK	GLN	333
3QRK	GLU	334
3QRK	VAL	335
3QRK	ASN	336
3QRK	ALA	337
3QRK	VAL	338
3QRK	VAL	339
3QRK	LEU	340
3QRK	LEU	341
3QRK	TYR	342
3QRK	MET	343
3QRK	ALA	344
3QRK	THR	345
3QRK	GLN	346
3QRK	ILE	347
3QRK	SER	348
3QRK	SER	349
3QRK	ALA	350
3QRK	MET	351
3QRK	GLU	352
3QRK	TYR	353
3QRK	LEU	354
3QRK	GLU	355
3QRK	LYS	356
3QRK	LYS	357
3QRK	ASN	358
3QRK	PHE	359
3QRK	ILE	360
3QRK	HIS	361
3QRK	ARG	362
3QRK	ASP	363
3QRK	LEU	364
3QRK	ALA	365
3QRK	ALA	366
3QRK	ARG	367
3QRK	ASN	368
3QRK	CYS	369
3QRK	LEU	370
3QRK	VAL	371
3QRK	GLY	372
3QRK	GLU	373
3QRK	ASN	374
3QRK	HIS	375
3QRK	LEU	376
3QRK	VAL	377
3QRK	LYS	378
3QRK	VAL	379
3QRK	ALA	380
3QRK	ASP	381
3QRK	PHE	382
3QRK	GLY	383
3QRK	LEU	384
3QRK	SER	385
3QRK	ARG	386
3QRK	LEU	387
3QRK	MET	388
3QRK	THR	389
3QRK	GLY	390
3QRK	ASP	391
3QRK	THR	392
3QRK	TYR	393
3QRK	THR	394
3QRK	ALA	395
3QRK	HIS	396
3QRK	ALA	397
3QRK	GLY	398
3QRK	ALA	399
3QRK	LYS	400
3QRK	PHE	401
3QRK	PRO	402
3QRK	ILE	403
3QRK	LYS	404
3QRK	TRP	405
3QRK	THR	406
3QRK	ALA	407
3QRK	PRO	408
3QRK	GLU	409
3QRK	SER	410
3QRK	LEU	411
3QRK	ALA	412
3QRK	TYR	413
3QRK	ASN	414
3QRK	LYS	415
3QRK	PHE	416
3QRK	SER	417
3QRK	ILE	418
3QRK	LYS	419
3QRK	SER	420
3QRK	ASP	421
3QRK	VAL	422
3QRK	TRP	423
3QRK	ALA	424
3QRK	PHE	425
3QRK	GLY	426
3QRK	VAL	427
3QRK	LEU	428
3QRK	LEU	429
3QRK	TRP	430
3QRK	GLU	431
3QRK	ILE	432
3QRK	ALA	433
3QRK	THR	434
3QRK	TYR	435
3QRK	GLY	436
3QRK	MET	437
3QRK	SER	438
3QRK	PRO	439
3QRK	TYR	440
3QRK	PRO	441
3QRK	GLY	442
3QRK	ILE	443
3QRK	ASP	444
3QRK	LEU	445
3QRK	SER	446
3QRK	GLN	447
3QRK	VAL	448
3QRK	TYR	449
3QRK	GLU	450
3QRK	LEU	451
3QRK	LEU	452
3QRK	GLU	453
3QRK	LYS	454
3QRK	ASP	455
3QRK	TYR	456
3QRK	ARG	457
3QRK	MET	458
3QRK	GLU	459
3QRK	ARG	460
3QRK	PRO	461
3QRK	GLU	462
3QRK	GLY	463
3QRK	CYS	464
3QRK	PRO	465
3QRK	GLU	466
3QRK	LYS	467
3QRK	VAL	468
3QRK	TYR	469
3QRK	GLU	470
3QRK	LEU	471
3QRK	MET	472
3QRK	ARG	473
3QRK	ALA	474
3QRK	CYS	475
3QRK	TRP	476
3QRK	GLN	477
3QRK	TRP	478
3QRK	ASN	479
3QRK	PRO	480
3QRK	SER	481
3QRK	ASP	482
3QRK	ARG	483
3QRK	PRO	484
3QRK	SER	485
3QRK	PHE	486
3QRK	ALA	487
3QRK	GLU	488
3QRK	ILE	489
3QRK	HIS	490
3QRK	GLN	491
3QRK	ALA	492
3QRK	PHE	493
3QRK	GLU	494
3QRK	THR	495
3QRK	MET	496
4TWP	ASP	233
4TWP	LYS	234
4TWP	TRP	235
4TWP	GLU	236
4TWP	MET	237
4TWP	GLU	238
4TWP	ARG	239
4TWP	THR	240
4TWP	ASP	241
4TWP	ILE	242
4TWP	THR	243
4TWP	MET	244
4TWP	LYS	245
4TWP	HIS	246
4TWP	LYS	247
4TWP	LEU	248
4TWP	GLY	249
4TWP	GLY	250
4TWP	GLY	251
4TWP	GLN	252
4TWP	TYR	253
4TWP	GLY	254
4TWP	GLU	255
4TWP	VAL	256
4TWP	TYR	257
4TWP	GLU	258
4TWP	GLY	259
4TWP	VAL	260
4TWP	TRP	261
4TWP	LYS	262
4TWP	LYS	263
4TWP	TYR	264
4TWP	SER	265
4TWP	LEU	266
4TWP	THR	267
4TWP	VAL	268
4TWP	ALA	269
4TWP	VAL	270
4TWP	LYS	271
4TWP	THR	272
4TWP	LEU	273
4TWP	GLU	279
4TWP	VAL	280
4TWP	GLU	281
4TWP	GLU	282
4TWP	PHE	283
4TWP	LEU	284
4TWP	LYS	285
4TWP	GLU	286
4TWP	ALA	287
4TWP	ALA	288
4TWP	VAL	289
4TWP	MET	290
4TWP	LYS	291
4TWP	GLU	292
4TWP	ILE	293
4TWP	LYS	294
4TWP	HIS	295
4TWP	PRO	296
4TWP	ASN	297
4TWP	LEU	298
4TWP	VAL	299
4TWP	GLN	300
4TWP	LEU	301
4TWP	LEU	302
4TWP	GLY	303
4TWP	VAL	304
4TWP	CYS	305
4TWP	THR	306
4TWP	ARG	307
4TWP	GLU	308
4TWP	PRO	309
4TWP	PRO	310
4TWP	PHE	311
4TWP	TYR	312
4TWP	ILE	313
4TWP	ILE	314
4TWP	ILE	315
4TWP	GLU	316
4TWP	PHE	317
4TWP	MET	318
4TWP	THR	319
4TWP	TYR	320
4TWP	GLY	321
4TWP	ASN	322
4TWP	LEU	323
4TWP	LEU	324
4TWP	ASP	325
4TWP	TYR	326
4TWP	LEU	327
4TWP	ARG	328
4TWP	GLU	329
4TWP	CYS	330
4TWP	ASN	331
4TWP	ARG	332
4TWP	GLN	333
4TWP	GLU	334
4TWP	VAL	335
4TWP	ASN	336
4TWP	ALA	337
4TWP	VAL	338
4TWP	VAL	339
4TWP	LEU	340
4TWP	LEU	341
4TWP	TYR	342
4TWP	MET	343
4TWP	ALA	344
4TWP	THR	345
4TWP	GLN	346
4TWP	ILE	347
4TWP	SER	348
4TWP	SER	349
4TWP	ALA	350
4TWP	MET	351
4TWP	GLU	352
4TWP	TYR	353
4TWP	LEU	354
4TWP	GLU	355
4TWP	LYS	356
4TWP	LYS	357
4TWP	ASN	358
4TWP	PHE	359
4TWP	ILE	360
4TWP	HIS	361
4TWP	ARG	362
4TWP	ASP	363
4TWP	LEU	364
4TWP	ALA	365
4TWP	ALA	366
4TWP	ARG	367
4TWP	ASN	368
4TWP	CYS	369
4TWP	LEU	370
4TWP	VAL	371
4TWP	GLY	372
4TWP	GLU	373
4TWP	ASN	374
4TWP	HIS	375
4TWP	LEU	376
4TWP	VAL	377
4TWP	LYS	378
4TWP	VAL	379
4TWP	ALA	380
4TWP	ASP	381
4TWP	PHE	382
4TWP	GLY	383
4TWP	LEU	384
4TWP	SER	385
4TWP	ARG	386
4TWP	LEU	387
4TWP	MET	388
4TWP	THR	389
4TWP	GLY	390
4TWP	ASP	391
4TWP	THR	392
4TWP	TYR	393
4TWP	THR	394
4TWP	ALA	395
4TWP	HIS	396
4TWP	ALA	397
4TWP	GLY	398
4TWP	ALA	399
4TWP	LYS	400
4TWP	PHE	401
4TWP	PRO	402
4TWP	ILE	403
4TWP	LYS	404
4TWP	TRP	405
4TWP	THR	406
4TWP	ALA	407
4TWP	PRO	408
4TWP	GLU	409
4TWP	SER	410
4TWP	LEU	411
4TWP	ALA	412
4TWP	TYR	413
4TWP	ASN	414
4TWP	LYS	415
4TWP	PHE	416
4TWP	SER	417
4TWP	ILE	418
4TWP	LYS	419
4TWP	SER	420
4TWP	ASP	421
4TWP	VAL	422
4TWP	TRP	423
4TWP	ALA	424
4TWP	PHE	425
4TWP	GLY	426
4TWP	VAL	427
4TWP	LEU	428
4TWP	LEU	429
4TWP	TRP	430
4TWP	GLU	431
4TWP	ILE	432
4TWP	ALA	433
4TWP	THR	434
4TWP	TYR	435
4TWP	GLY	436
4TWP	MET	437
4TWP	SER	438
4TWP	PRO	439
4TWP	TYR	440
4TWP	PRO	441
4TWP	GLY	442
4TWP	ILE	443
4TWP	ASP	444
4TWP	LEU	445
4TWP	SER	446
4TWP	GLN	447
4TWP	VAL	448
4TWP	TYR	449
4TWP	GLU	450
4TWP	LEU	451
4TWP	LEU	452
4TWP	GLU	453
4TWP	LYS	454
4TWP	ASP	455
4TWP	TYR	456
4TWP	ARG	457
4TWP	MET	458
4TWP	GLU	459
4TWP	ARG	460
4TWP	PRO	461
4TWP	GLU	462
4TWP	GLY	463
4TWP	CYS	464
4TWP	PRO	465
4TWP	GLU	466
4TWP	LYS	467
4TWP	VAL	468
4TWP	TYR	469
4TWP	GLU	470
4TWP	LEU	471
4TWP	MET	472
4TWP	ARG	473
4TWP	ALA	474
4TWP	CYS	475
4TWP	TRP	476
4TWP	GLN	477
4TWP	TRP	478
4TWP	ASN	479
4TWP	PRO	480
4TWP	SER	481
4TWP	ASP	482
4TWP	ARG	483
4TWP	PRO	484
4TWP	SER	485
4TWP	PHE	486
4TWP	ALA	487
4TWP	GLU	488
4TWP	ILE	489
4TWP	HIS	490
4TWP	GLN	491
4TWP	ALA	492
4TWP	PHE	493
4TWP	GLU	494
4TWP	THR	495
4TWP	MET	496
4TWP	PHE	497
4TWP	GLN	498
4TWP	GLU	499
4TWP	SER	500
4TWP	SER	501
4TWP	ILE	502
4TWP	SER	503
4TWP	ASP	233
4TWP	LYS	234
4TWP	TRP	235
4TWP	GLU	236
4TWP	MET	237
4TWP	GLU	238
4TWP	ARG	239
4TWP	THR	240
4TWP	ASP	241
4TWP	ILE	242
4TWP	THR	243
4TWP	MET	244
4TWP	LYS	245
4TWP	HIS	246
4TWP	LYS	247
4TWP	LEU	248
4TWP	GLY	249
4TWP	GLY	250
4TWP	GLY	251
4TWP	GLN	252
4TWP	TYR	253
4TWP	GLY	254
4TWP	GLU	255
4TWP	VAL	256
4TWP	TYR	257
4TWP	GLU	258
4TWP	GLY	259
4TWP	VAL	260
4TWP	TRP	261
4TWP	LYS	262
4TWP	LYS	263
4TWP	TYR	264
4TWP	SER	265
4TWP	LEU	266
4TWP	THR	267
4TWP	VAL	268
4TWP	ALA	269
4TWP	VAL	270
4TWP	LYS	271
4TWP	THR	272
4TWP	LEU	273
4TWP	LYS	274
4TWP	GLU	275
4TWP	ASP	276
4TWP	THR	277
4TWP	MET	278
4TWP	GLU	279
4TWP	VAL	280
4TWP	GLU	281
4TWP	GLU	282
4TWP	PHE	283
4TWP	LEU	284
4TWP	LYS	285
4TWP	GLU	286
4TWP	ALA	287
4TWP	ALA	288
4TWP	VAL	289
4TWP	MET	290
4TWP	LYS	291
4TWP	GLU	292
4TWP	ILE	293
4TWP	LYS	294
4TWP	HIS	295
4TWP	PRO	296
4TWP	ASN	297
4TWP	LEU	298
4TWP	VAL	299
4TWP	GLN	300
4TWP	LEU	301
4TWP	LEU	302
4TWP	GLY	303
4TWP	VAL	304
4TWP	CYS	305
4TWP	THR	306
4TWP	ARG	307
4TWP	GLU	308
4TWP	PRO	309
4TWP	PRO	310
4TWP	PHE	311
4TWP	TYR	312
4TWP	ILE	313
4TWP	ILE	314
4TWP	ILE	315
4TWP	GLU	316
4TWP	PHE	317
4TWP	MET	318
4TWP	THR	319
4TWP	TYR	320
4TWP	GLY	321
4TWP	ASN	322
4TWP	LEU	323
4TWP	LEU	324
4TWP	ASP	325
4TWP	TYR	326
4TWP	LEU	327
4TWP	ARG	328
4TWP	GLU	329
4TWP	CYS	330
4TWP	ASN	331
4TWP	ARG	332
4TWP	GLN	333
4TWP	GLU	334
4TWP	VAL	335
4TWP	ASN	336
4TWP	ALA	337
4TWP	VAL	338
4TWP	VAL	339
4TWP	LEU	340
4TWP	LEU	341
4TWP	TYR	342
4TWP	MET	343
4TWP	ALA	344
4TWP	THR	345
4TWP	GLN	346
4TWP	ILE	347
4TWP	SER	348
4TWP	SER	349
4TWP	ALA	350
4TWP	MET	351
4TWP	GLU	352
4TWP	TYR	353
4TWP	LEU	354
4TWP	GLU	355
4TWP	LYS	356
4TWP	LYS	357
4TWP	ASN	358
4TWP	PHE	359
4TWP	ILE	360
4TWP	HIS	361
4TWP	ARG	362
4TWP	ASP	363
4TWP	LEU	364
4TWP	ALA	365
4TWP	ALA	366
4TWP	ARG	367
4TWP	ASN	368
4TWP	CYS	369
4TWP	LEU	370
4TWP	VAL	371
4TWP	GLY	372
4TWP	GLU	373
4TWP	ASN	374
4TWP	HIS	375
4TWP	LEU	376
4TWP	VAL	377
4TWP	LYS	378
4TWP	VAL	379
4TWP	ALA	380
4TWP	ASP	381
4TWP	PHE	382
4TWP	GLY	383
4TWP	LEU	384
4TWP	SER	385
4TWP	ARG	386
4TWP	LEU	387
4TWP	MET	388
4TWP	THR	389
4TWP	GLY	390
4TWP	ASP	391
4TWP	THR	392
4TWP	TYR	393
4TWP	THR	394
4TWP	ALA	395
4TWP	HIS	396
4TWP	ALA	397
4TWP	GLY	398
4TWP	ALA	399
4TWP	LYS	400
4TWP	PHE	401
4TWP	PRO	402
4TWP	ILE	403
4TWP	LYS	404
4TWP	TRP	405
4TWP	THR	406
4TWP	ALA	407
4TWP	PRO	408
4TWP	GLU	409
4TWP	SER	410
4TWP	LEU	411
4TWP	ALA	412
4TWP	TYR	413
4TWP	ASN	414
4TWP	LYS	415
4TWP	PHE	416
4TWP	SER	417
4TWP	ILE	418
4TWP	LYS	419
4TWP	SER	420
4TWP	ASP	421
4TWP	VAL	422
4TWP	TRP	423
4TWP	ALA	424
4TWP	PHE	425
4TWP	GLY	426
4TWP	VAL	427
4TWP	LEU	428
4TWP	LEU	429
4TWP	TRP	430
4TWP	GLU	431
4TWP	ILE	432
4TWP	ALA	433
4TWP	THR	434
4TWP	TYR	435
4TWP	GLY	436
4TWP	MET	437
4TWP	SER	438
4TWP	PRO	439
4TWP	TYR	440
4TWP	PRO	441
4TWP	GLY	442
4TWP	ILE	443
4TWP	ASP	444
4TWP	LEU	445
4TWP	SER	446
4TWP	GLN	447
4TWP	VAL	448
4TWP	TYR	449
4TWP	GLU	450
4TWP	LEU	451
4TWP	LEU	452
4TWP	GLU	453
4TWP	LYS	454
4TWP	ASP	455
4TWP	TYR	456
4TWP	ARG	457
4TWP	MET	458
4TWP	GLU	459
4TWP	ARG	460
4TWP	PRO	461
4TWP	GLU	462
4TWP	GLY	463
4TWP	CYS	464
4TWP	PRO	465
4TWP	GLU	466
4TWP	LYS	467
4TWP	VAL	468
4TWP	TYR	469
4TWP	GLU	470
4TWP	LEU	471
4TWP	MET	472
4TWP	ARG	473
4TWP	ALA	474
4TWP	CYS	475
4TWP	TRP	476
4TWP	GLN	477
4TWP	TRP	478
4TWP	ASN	479
4TWP	PRO	480
4TWP	SER	481
4TWP	ASP	482
4TWP	ARG	483
4TWP	PRO	484
4TWP	SER	485
4TWP	PHE	486
4TWP	ALA	487
4TWP	GLU	488
4TWP	ILE	489
4TWP	HIS	490
4TWP	GLN	491
4TWP	ALA	492
4TWP	PHE	493
4TWP	GLU	494
4TWP	THR	495
4TWP	MET	496
4TWP	PHE	497
4TWP	GLN	498
4TWP	GLU	499
4TWP	SER	500
4TWP	SER	501
4TWP	ILE	502
4TWP	SER	503
5HU9	ALA	225
5HU9	MET	226
5HU9	GLY	227
5HU9	SER	228
5HU9	SER	229
5HU9	PRO	230
5HU9	ASN	231
5HU9	TYR	232
5HU9	ASP	233
5HU9	LYS	234
5HU9	TRP	235
5HU9	GLU	236
5HU9	MET	237
5HU9	GLU	238
5HU9	ARG	239
5HU9	THR	240
5HU9	ASP	241
5HU9	ILE	242
5HU9	THR	243
5HU9	MET	244
5HU9	LYS	245
5HU9	HIS	246
5HU9	LYS	247
5HU9	LEU	248
5HU9	GLY	249
5HU9	GLY	250
5HU9	GLY	251
5HU9	GLN	252
5HU9	TYR	253
5HU9	GLY	254
5HU9	GLU	255
5HU9	VAL	256
5HU9	TYR	257
5HU9	GLU	258
5HU9	GLY	259
5HU9	VAL	260
5HU9	TRP	261
5HU9	LYS	262
5HU9	LYS	263
5HU9	TYR	264
5HU9	SER	265
5HU9	LEU	266
5HU9	THR	267
5HU9	VAL	268
5HU9	ALA	269
5HU9	VAL	270
5HU9	LYS	271
5HU9	THR	272
5HU9	LEU	273
5HU9	LYS	274
5HU9	GLU	275
5HU9	ASP	276
5HU9	THR	277
5HU9	MET	278
5HU9	GLU	279
5HU9	VAL	280
5HU9	GLU	281
5HU9	GLU	282
5HU9	PHE	283
5HU9	LEU	284
5HU9	LYS	285
5HU9	GLU	286
5HU9	ALA	287
5HU9	ALA	288
5HU9	VAL	289
5HU9	MET	290
5HU9	LYS	291
5HU9	GLU	292
5HU9	ILE	293
5HU9	LYS	294
5HU9	HIS	295
5HU9	PRO	296
5HU9	ASN	297
5HU9	LEU	298
5HU9	VAL	299
5HU9	GLN	300
5HU9	LEU	301
5HU9	LEU	302
5HU9	GLY	303
5HU9	VAL	304
5HU9	CYS	305
5HU9	THR	306
5HU9	ARG	307
5HU9	GLU	308
5HU9	PRO	309
5HU9	PRO	310
5HU9	PHE	311
5HU9	TYR	312
5HU9	ILE	313
5HU9	ILE	314
5HU9	THR	315
5HU9	GLU	316
5HU9	PHE	317
5HU9	MET	318
5HU9	THR	319
5HU9	TYR	320
5HU9	GLY	321
5HU9	ASN	322
5HU9	LEU	323
5HU9	LEU	324
5HU9	ASP	325
5HU9	TYR	326
5HU9	LEU	327
5HU9	ARG	328
5HU9	GLU	329
5HU9	CYS	330
5HU9	ASN	331
5HU9	ARG	332
5HU9	GLN	333
5HU9	GLU	334
5HU9	VAL	335
5HU9	ASN	336
5HU9	ALA	337
5HU9	VAL	338
5HU9	VAL	339
5HU9	LEU	340
5HU9	LEU	341
5HU9	TYR	342
5HU9	MET	343
5HU9	ALA	344
5HU9	THR	345
5HU9	GLN	346
5HU9	ILE	347
5HU9	SER	348
5HU9	SER	349
5HU9	ALA	350
5HU9	MET	351
5HU9	GLU	352
5HU9	TYR	353
5HU9	LEU	354
5HU9	GLU	355
5HU9	LYS	356
5HU9	LYS	357
5HU9	ASN	358
5HU9	PHE	359
5HU9	ILE	360
5HU9	HIS	361
5HU9	ARG	362
5HU9	ASP	363
5HU9	LEU	364
5HU9	ALA	365
5HU9	ALA	366
5HU9	ARG	367
5HU9	ASN	368
5HU9	CYS	369
5HU9	LEU	370
5HU9	VAL	371
5HU9	GLY	372
5HU9	GLU	373
5HU9	ASN	374
5HU9	HIS	375
5HU9	LEU	376
5HU9	VAL	377
5HU9	LYS	378
5HU9	VAL	379
5HU9	ALA	380
5HU9	ASP	381
5HU9	PHE	382
5HU9	GLY	383
5HU9	LEU	384
5HU9	SER	385
5HU9	ARG	386
5HU9	LEU	387
5HU9	MET	388
5HU9	THR	394
5HU9	ALA	395
5HU9	HIS	396
5HU9	ALA	397
5HU9	GLY	398
5HU9	ALA	399
5HU9	LYS	400
5HU9	PHE	401
5HU9	PRO	402
5HU9	ILE	403
5HU9	LYS	404
5HU9	TRP	405
5HU9	THR	406
5HU9	ALA	407
5HU9	PRO	408
5HU9	GLU	409
5HU9	SER	410
5HU9	LEU	411
5HU9	ALA	412
5HU9	TYR	413
5HU9	ASN	414
5HU9	LYS	415
5HU9	PHE	416
5HU9	SER	417
5HU9	ILE	418
5HU9	LYS	419
5HU9	SER	420
5HU9	ASP	421
5HU9	VAL	422
5HU9	TRP	423
5HU9	ALA	424
5HU9	PHE	425
5HU9	GLY	426
5HU9	VAL	427
5HU9	LEU	428
5HU9	LEU	429
5HU9	TRP	430
5HU9	GLU	431
5HU9	ILE	432
5HU9	ALA	433
5HU9	THR	434
5HU9	TYR	435
5HU9	GLY	436
5HU9	MET	437
5HU9	SER	438
5HU9	PRO	439
5HU9	TYR	440
5HU9	PRO	441
5HU9	GLY	442
5HU9	ILE	443
5HU9	ASP	444
5HU9	LEU	445
5HU9	SER	446
5HU9	GLN	447
5HU9	VAL	448
5HU9	TYR	449
5HU9	GLU	450
5HU9	LEU	451
5HU9	LEU	452
5HU9	GLU	453
5HU9	LYS	454
5HU9	ASP	455
5HU9	TYR	456
5HU9	ARG	457
5HU9	MET	458
5HU9	GLU	459
5HU9	ARG	460
5HU9	PRO	461
5HU9	GLU	462
5HU9	GLY	463
5HU9	CYS	464
5HU9	PRO	465
5HU9	GLU	466
5HU9	LYS	467
5HU9	VAL	468
5HU9	TYR	469
5HU9	GLU	470
5HU9	LEU	471
5HU9	MET	472
5HU9	ARG	473
5HU9	ALA	474
5HU9	CYS	475
5HU9	TRP	476
5HU9	GLN	477
5HU9	TRP	478
5HU9	ASN	479
5HU9	PRO	480
5HU9	SER	481
5HU9	ASP	482
5HU9	ARG	483
5HU9	PRO	484
5HU9	SER	485
5HU9	PHE	486
5HU9	ALA	487
5HU9	GLU	488
5HU9	ILE	489
5HU9	HIS	490
5HU9	GLN	491
5HU9	ALA	492
5HU9	PHE	493
5HU9	GLU	494
5HU9	THR	495
5HU9	MET	496
5HU9	PHE	497
5HU9	GLN	498
5HU9	GLU	499

Top

Ramachandran Plot of Kinase Fusion Protein Structure

Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.

37_BCR_ABL1_ramachandran.png

HKFP_45_BCR_ABL1_ramachandran.png

HKFP_46_BCR_ABL1_ramachandran.png

HKFP_47_BCR_ABL1_ramachandran.png

HKFP_48_BCR_ABL1_ramachandran.png

HKFP_50_BCR_ABL1_ramachandran.png

57_BCR_ABL1_ramachandran.png

TKFP_100_BCR_ABL1_ramachandran.png

TKFP_101_BCR_ABL1_ramachandran.png

TKFP_84_BCR_ABL1_ramachandran.png

TKFP_85_BCR_ABL1_ramachandran.png

TKFP_86_BCR_ABL1_ramachandran.png

TKFP_87_BCR_ABL1_ramachandran.png

TKFP_88_BCR_ABL1_ramachandran.png

TKFP_89_BCR_ABL1_ramachandran.png

TKFP_99_BCR_ABL1_ramachandran.png

Top

Virtual Screening Results

Distribution of the average docking score across all approved kinase inhibitors. Distribution of the number of occurrence across all approved kinase inhibitors.

5'-kinase fusion protein case

3'-kinase fusion protein case

Top

Drug information from DrugBank of the top 20 interacting small molecules. * The detailed information of individual kinase inhibitors are available in the download page.

Fusion gene name info	Drug	Docking score	Glide g score	Glide energy
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Midostaurin	-9.97034	-9.97034	-48.8856
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Midostaurin	-9.66896	-9.66896	-48.5938
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Midostaurin	-9.16851	-9.16851	-51.4279
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Larotrectinib	-9.0292	-9.0292	-52.8338
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Larotrectinib	-8.71696	-8.71696	-51.9162
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Pexidartinib	-7.7725300000000015	-8.47333	-48.3647
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Pexidartinib	-7.7725300000000015	-8.47333	-48.3647
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Ponatinib	-7.3986	-7.6052	-54.8679
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Ponatinib	-7.3986	-7.6052	-54.8679
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Ponatinib	-7.3986	-7.6052	-54.8679
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Palbociclib	-7.31733	-7.72423	-47.2513
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Palbociclib	-7.31733	-7.72423	-47.2513
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Selpercatinib	-7.25005	-7.28055	-56.2434
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Selpercatinib	-7.25005	-7.28055	-56.2434
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Palbociclib	-7.16712	-7.57402	-46.2675
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Lapatinib	-7.13513	-7.22393	-67.5116
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Pexidartinib	-7.12534	-7.34214	-42.4779
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Pexidartinib	-7.12534	-7.34214	-42.4779
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Lapatinib	-7.10173	-7.19053	-65.5893
HKFP_45_BCR_ABL1_vsw_5-DOCK_HTVS_1-001	Larotrectinib	-7.09386	-7.09386	-44.5201
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Infigratinib	-8.58657	-9.15337	-55.8668
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Infigratinib	-8.58657	-9.15337	-55.8668
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Infigratinib	-8.58657	-9.15337	-55.8668
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Nilotinib	-8.3382	-8.4778	-64.2929
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Nilotinib	-8.3382	-8.4778	-64.2929
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Neratinib	-7.89412	-8.79642	-50.1757
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Neratinib	-7.89412	-8.79642	-50.1757
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Axitinib	-7.71007	-7.71327	-40.2824
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Neratinib	-7.5172	-8.4231	-47.5104
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Zanubrutinib	-7.41557	-7.41557	-49.5816
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Pexidartinib	-7.259760000000001	-7.476560000000001	-41.0567
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Pexidartinib	-7.259760000000001	-7.476560000000001	-41.0567
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Asciminib	-7.227530000000002	-7.69253	-52.6225
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Asciminib	-7.11647	-7.581469999999999	-52.3788
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Ibrutinib	-7.09813	-7.09813	-43.3777
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Asciminib	-7.0323699999999985	-7.395469999999999	-47.4595
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Pexidartinib	-7.02575	-7.72655	-47.0344
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Pexidartinib	-7.02575	-7.72655	-47.0344
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Asciminib	-7.002960000000002	-7.4679600000000015	-51.2508
HKFP_46_BCR_ABL1-vsw_1-DOCK_HTVS_1-001	Lapatinib	-6.96955	-7.05835	-53.4502
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Dacomitinib	-8.7655	-8.8738	-53.8739
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Dacomitinib	-8.7655	-8.8738	-53.8739
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Afatinib	-8.51576	-8.69806	-46.6048
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Afatinib	-8.51576	-8.69806	-46.6048
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Afatinib	-8.51436	-8.69806	-46.6048
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Futibatinib	-7.8235899999999985	-7.8235899999999985	-41.5058
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Pexidartinib	-7.59575	-7.81255	-43.4012
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Pexidartinib	-7.59575	-7.81255	-43.4012
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Lapatinib	-7.424469999999999	-7.513269999999999	-64.7624
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Larotrectinib	-7.38713	-7.38713	-45.2595
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Afatinib	-7.227760000000001	-8.13006	-42.8929
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Afatinib	-7.227760000000001	-8.13006	-42.8929
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Afatinib	-7.2263600000000014	-8.13006	-42.8929
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Larotrectinib	-7.0963	-7.0963	-43.28100000000001
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Avapritinib	-7.006869999999998	-7.33817	-46.0971
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Avapritinib	-7.006869999999998	-7.33817	-46.0971
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Avapritinib	-7.006869999999998	-7.33817	-46.0971
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Avapritinib	-7.006869999999998	-7.33817	-46.0971
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Pexidartinib	-6.95067	-7.65147	-44.3943
HKFP_47_BCR_ABL1-vsw_2-DOCK_HTVS_1-001	Pexidartinib	-6.95067	-7.65147	-44.3943
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Neratinib	-7.1667	-7.349	-61.8708
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Neratinib	-7.1667	-7.349	-61.8708
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Lapatinib	-6.683389999999998	-6.772189999999998	-64.4969
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Palbociclib	-6.57804	-6.984939999999999	-57.3692
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Neratinib	-6.5667800000000005	-7.46908	-63.4628
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Neratinib	-6.5667800000000005	-7.46908	-63.4628
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Neratinib	-6.54657	-6.732469999999998	-56.2247
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Lapatinib	-6.49639	-6.585189999999999	-63.6454
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Neratinib	-6.31476	-7.22066	-65.0385
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Larotrectinib	-6.14393	-6.14393	-41.7114
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Tepotinib	-6.0103	-6.0114	-55.5848
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Larotrectinib	-5.9807	-5.9807	-42.5221
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Midostaurin	-5.91681	-5.91681	-50.9432
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Bosutinib	-5.90638	-6.01958	-46.8557
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Bosutinib	-5.90638	-6.01958	-46.8557
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Bosutinib	-5.90638	-6.01958	-46.8557
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Upadacitinib	-5.84738	-5.8483800000000015	-39.1369
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Everolimus	-5.8166400000000005	-5.81804	-54.159
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Palbociclib	-5.8052	-6.2747	-53.7506
HKFP_48_BCR_ABL1-vsw_3-DOCK_HTVS_1-001	Palbociclib	-5.8052	-6.2747	-53.7506
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Lapatinib	-8.77438	-8.86318	-58.5376
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Lapatinib	-8.55786	-8.64666	-56.678
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Nilotinib	-8.37403	-8.513630000000001	-55.493
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Nilotinib	-8.37403	-8.513630000000001	-55.493
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Tepotinib	-7.812880000000002	-7.81398	-56.8231
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Pralsetinib	-7.58788	-7.67938	-53.8866
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Brigatinib	-7.58135	-7.59485	-58.7408
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Brigatinib	-7.58135	-7.59485	-58.7408
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Tepotinib	-7.56509	-7.56619	-54.7827
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Ponatinib	-7.040260000000001	-7.246860000000002	-49.5984
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Ponatinib	-7.040260000000001	-7.246860000000002	-49.5984
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Ponatinib	-7.040260000000001	-7.246860000000002	-49.5984
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Nilotinib	-6.971260000000001	-7.89606	-54.5258
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Nilotinib	-6.971260000000001	-7.89606	-54.5258
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Tepotinib	-6.93332	-6.9344199999999985	-54.194
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Acalabrutinib	-6.90313	-6.91723	-51.1614
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Acalabrutinib	-6.90313	-6.91723	-51.1614
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Tepotinib	-6.88679	-6.88789	-52.4787
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Vemurafenib	-6.79824	-7.17744	-45.2959
HKFP_50_BCR_ABL1-vsw_4-DOCK_HTVS_1-001	Vemurafenib	-6.79824	-7.17744	-45.2959
37_BCR_ABL1-DOCK_HTVS_1-001	Midostaurin	-8.9625	-8.9625	-52.6912
37_BCR_ABL1-DOCK_HTVS_1-001	Larotrectinib	-8.95903	-8.95903	-51.5067
37_BCR_ABL1-DOCK_HTVS_1-001	Larotrectinib	-8.73073	-8.73073	-45.1836
37_BCR_ABL1-DOCK_HTVS_1-001	Tepotinib	-8.42908	-8.43018	-57.2048
37_BCR_ABL1-DOCK_HTVS_1-001	Axitinib	-8.35253	-8.35573	-39.5524
37_BCR_ABL1-DOCK_HTVS_1-001	Afatinib	-8.14569	-8.32799	-48.1015
37_BCR_ABL1-DOCK_HTVS_1-001	Afatinib	-8.14569	-8.32799	-48.1015
37_BCR_ABL1-DOCK_HTVS_1-001	Afatinib	-8.14429	-8.32799	-48.1015
37_BCR_ABL1-DOCK_HTVS_1-001	Upadacitinib	-7.9881	-7.9891	-30.5868
37_BCR_ABL1-DOCK_HTVS_1-001	Afatinib	-7.847389999999999	-8.029689999999999	-50.3055
37_BCR_ABL1-DOCK_HTVS_1-001	Afatinib	-7.847389999999999	-8.029689999999999	-50.3055
37_BCR_ABL1-DOCK_HTVS_1-001	Afatinib	-7.84599	-8.029689999999999	-50.3055
37_BCR_ABL1-DOCK_HTVS_1-001	Midostaurin	-7.61643	-7.61643	-48.5654
37_BCR_ABL1-DOCK_HTVS_1-001	Ripretinib	-7.5777	-7.5847	-53.2718
37_BCR_ABL1-DOCK_HTVS_1-001	Ripretinib	-7.5777	-7.5847	-53.2718
37_BCR_ABL1-DOCK_HTVS_1-001	Ponatinib	-7.56906	-7.77566	-54.7924
37_BCR_ABL1-DOCK_HTVS_1-001	Ponatinib	-7.56906	-7.77566	-54.7924
37_BCR_ABL1-DOCK_HTVS_1-001	Ponatinib	-7.56906	-7.77566	-54.7924
37_BCR_ABL1-DOCK_HTVS_1-001	Cobimetinib	-7.5586	-7.5614	-49.7809
37_BCR_ABL1-DOCK_HTVS_1-001	Pemigatinib	-7.536980000000001	-7.619680000000001	-43.4973
57_BCR_ABL1-DOCK_HTVS_1-001	Vemurafenib	-8.03075	-8.40995	-47.9359
57_BCR_ABL1-DOCK_HTVS_1-001	Vemurafenib	-8.03075	-8.40995	-47.9359
57_BCR_ABL1-DOCK_HTVS_1-001	Avapritinib	-7.8131699999999995	-8.610669999999999	-59.7317
57_BCR_ABL1-DOCK_HTVS_1-001	Avapritinib	-7.8131699999999995	-8.610669999999999	-59.7317
57_BCR_ABL1-DOCK_HTVS_1-001	Avapritinib	-7.8131699999999995	-8.610669999999999	-59.7317
57_BCR_ABL1-DOCK_HTVS_1-001	Avapritinib	-7.8131699999999995	-8.610669999999999	-59.7317
57_BCR_ABL1-DOCK_HTVS_1-001	Ripretinib	-7.80139	-7.808389999999999	-49.3344
57_BCR_ABL1-DOCK_HTVS_1-001	Ripretinib	-7.80139	-7.808389999999999	-49.3344
57_BCR_ABL1-DOCK_HTVS_1-001	Vemurafenib	-7.73654	-8.180539999999999	-46.2388
57_BCR_ABL1-DOCK_HTVS_1-001	Vemurafenib	-7.73654	-8.180539999999999	-46.2388
57_BCR_ABL1-DOCK_HTVS_1-001	Ibrutinib	-7.66	-7.66	-45.4528
57_BCR_ABL1-DOCK_HTVS_1-001	Asciminib	-7.36837	-7.8333699999999995	-58.5231
57_BCR_ABL1-DOCK_HTVS_1-001	Avapritinib	-7.34698	-8.14448	-58.8766
57_BCR_ABL1-DOCK_HTVS_1-001	Avapritinib	-7.34698	-8.14448	-58.8766
57_BCR_ABL1-DOCK_HTVS_1-001	Avapritinib	-7.34698	-8.14448	-58.8766
57_BCR_ABL1-DOCK_HTVS_1-001	Avapritinib	-7.34698	-8.14448	-58.8766
57_BCR_ABL1-DOCK_HTVS_1-001	Netarsudil	-7.24097	-7.25207	-40.5451
57_BCR_ABL1-DOCK_HTVS_1-001	Netarsudil	-7.24097	-7.25207	-40.5451
57_BCR_ABL1-DOCK_HTVS_1-001	Lapatinib	-7.172110000000001	-7.260910000000001	-46.3529
57_BCR_ABL1-DOCK_HTVS_1-001	Asciminib	-7.152419999999999	-7.61742	-54.3308

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Kinase-Substrate Information of BCR_ABL1

Phosphorylation target of the kinase (phosphosite, 03-17-2024)

Kinase	Kinase UniProt Acc	Kinase species	Substrate	Substrate UniProt Acc	Substrate phosphorylated residues	Substrate phosphorylated sites (+/-7AA)	Domain
ABL1	P00519	human	YAP1	P46937	Y407	sGLsMsSySVPRtPD
ABL1	P00519	human	DCBLD2	Q96PD2	Y750	PAPDELVyQVPQStQ
ABL1	P00519	human	SMAD4	Q13485	Y301	MPPHPGHyWPVHNEL
ABL1	P00519	human	DCBLD1	Q8N8Z6	S657	GDyQRPHsAQPADRG
ABL1	P00519	human	TBX21	Q9UL17	Y305	QFIAVTAyQNAEITQ	T-box
ABL1	P00519	human	CAT	P04040	Y231	NANGEAVyCkFHYkT	Catalase
ABL1	P00519	human	MYLK	Q15746	Y1449	EKEPEVDyRTVTINT
ABL1	P00519	human	ABL1	P00519	Y393	RLMtGDtytAHAGAk	PK_Tyr_Ser-Thr
ABL1	P00519	human	TP73	O15350	Y99	SVPTHSPyAQPSSTF
ABL1	P00519	human	DCBLD2	Q96PD2	Y715	PPPLVGtyNtLLsRt
ABL1	P00519	human	SORBS2	O94875-2	Y59	RPFSPSAySLPASLN
ABL1	P00519	human	DCBLD2	Q96PD2	Y565	KKkTEGtyDLPyWDR
ABL1	P00519	human	CDC73	Q6P1J9	Y315	KIDTMGTyHGMTLkS
ABL1	P00519	human	DCBLD1	Q8N8Z6	S695	THPGTsDsysAPRDC
ABL1	P00519	human	MET	P08581	Y1349	stFIGEHyVHVNAty
ABL1	P00519	human	HRAS	P01112	Y137	AQDLARSyGIPYIEt	Ras
ABL1	P00519	human	MYC	P01106	Y89	sGLCsPSyVAVtPFs	Myc_N
ABL1	P00519	human	MDM4	O15151	Y55	TVKEVMHyLGQYIMV	SWIB
ABL1	P00519	human	PIK3AP1	Q6ZUJ8	Y513	LGQEEDVyHTVDDDE
ABL1	P00519	human	PDGFRB	P09619	Y970	GEGYKKKyQQVDEEF
ABL1	P00519	human	KAT5	Q92993	Y294	HPPGNEIyRkGTISF	MOZ_SAS
ABL1	P00519	human	MYC	P01106	Y47	CDEEENFyQQQQQSE	Myc_N
ABL1	P00519	human	CRK	P46108	Y221	GGPEPGPyAQPsVNt
ABL1	P00519	human	CASP9	P55211	Y153	RGNADLAyILSMEPC
ABL1	P00519	human	PLSCR1	O15162	Y69	PVPNQPVyNQPVyNQ
ABL1	P00519	human	ANXA1	P04083	Y21	IENEEQEyVQtVkss
ABL1	P00519	human	PXN	P49023	Y118	VGEEEHVysFPNkQk	Paxillin
ABL1	P00519	human	SMAD4	Q13485	Y195	NRASTETyStPALLA
ABL1	P00519	human	ROBO1	Q9Y6N7	Y1038	MLPESTVyGDVDLSN
ABL1	P00519	human	CRKL	P46109	Y207	IPEPAHAyAQPQttt
ABL1	P00519	human	VAV1	P15498	Y174	EAEGDEIyEDLMRsE
ABL1	P00519	human	TP63	Q9H3D4	Y290	RQSVLVPyEPPQVGT	P53
ABL1	P00519	human	DCBLD2	Q96PD2	T756	VyQVPQStQEVsGAG
ABL1	P00519	human	RB1	P06400	Y805	rIPGGNIyIsPLksP	Rb_C
ABL1	P00519	human	NOX5	Q96PH1	Y476	FHYRPGDyLyLNIPT	FAD_binding_8
ABL1	P00519	human	FHL2	Q14192	Y176	ITTGGVtyREQPWHK	LIM
ABL1	P00519	human	MDM2	Q00987	Y394	QsQESEDysQPSTSS
ABL1	P00519	human	ESR1	P03372	Y219	sIQGHNDyMCPATNQ	zf-C4
ABL1	P00519	human	RAPGEF1	Q13905	Y504	APIPSVPyAPFAAIL
ABL1	P00519	human	PLK1	P53350	Y445	DSTRLILyNDGDsLQ	POLO_box
ABL1	P00519	human	CRK	P46108	Y239	NLQNGPIyARVIQKR	SH3_2
ABL1	P00519	human	ZAP70	P43403	Y319	tsVyEsPysDPEELk
ABL1	P00519	human	JUNB	P17275	Y182	GPEPPPVyTNLSSyS	Jun
ABL1	P00519	human	EGFR	P00533	Y1092	tFLPVPEyINQsVPk
ABL1	P00519	human	DCBLD2	Q96PD2	S600	tPVRysssEVNHLsP
ABL1	P00519	human	ABI1	Q8IZP0	Y213	PPtVPNDyMtsPARL
ABL1	P00519	human	MAVS	Q7Z434	Y30	DVVEILPyLPCLTAR	CARD_2
ABL1	P00519	human	PHF5A	Q7RTV0	Y36	kCVICDSyVRPCTLV	PHF5
ABL1	P00519	human	TP63	Q9H3D4	Y149	SVTAPSPyAQPSSTF
ABL1	P00519	human	ABL1	P00519-2	Y412	RLMTGDtyTAHAGAK	PK_Tyr_Ser-Thr
ABL1	P00519	human	DCBLD1	Q8N8Z6	S697	PGTsDsysAPRDCLT
ABL1	P00519	human	PXN	P49023	Y31	FLSEEtPysyPtGNH
ABL1	P00519	human	WASF3	Q9UPY6	Y151	KKDGLKFyTDPSyFF
ABL1	P00519	human	DCBLD1	Q8N8Z6	Y665	AQPADRGyDRPKAVs
ABL1	P00519	human	PDGFRB	P09619	Y686	IITEyCRyGDLVDyL	PK_Tyr_Ser-Thr
ABL1	P00519	human	DCBLD2	Q96PD2	S598	EEtPVRysssEVNHL
ABL1	P00519	human	CDC73	Q6P1J9	Y293	IPAAyNRyDQERFkG	CDC73_N
ABL1	P00519	human	CASP9	P55211	Y397	AVSVkGIyKQMPGCF	Peptidase_C14
ABL1	P00519	human	PYCARD	Q9ULZ3	Y146	kVLTDEQyQAVRAEP	CARD
ABL1	P00519	human	CD19	P15391	Y508	EDMRGILyAAPQLRs
ABL1	P00519	human	CDKN1B	P46527	Y88	kGsLPEFyyRPPRPP
ABL1	P00519	human	CTNNB1	P35222	Y86	VADIDGQyAMTRAQR
ABL1	P00519	human	FOXA1	P55317	Y429	QALQYsPyGSTLPAS	HNF_C
ABL1	P00519	human	MYLK	Q15746	Y792	QPWHAGQyEILLKNR	I-set
ABL1	P00519	human	MYLK	Q15746	Y464	QEGsIEVyEDAGsHy	I-set
ABL1	P00519	human	DCBLD2	Q96PD2	Y655	GyADLDPyNsPGQEV
ABL1	P00519	human	JUNB	P17275	Y173	PAGPGGVyAGPEPPP	Jun
ABL1	P00519	human	SNCA	P37840	Y125	VDPDNEAyEMPsEEG	Synuclein
ABL1	P00519	human	NOX5	Q96PH1	Y478	YRPGDyLyLNIPTIA	FAD_binding_8
ABL1	P00519	human	MYLK	Q15746	Y231	NQDDVGVyTCLVVNG	I-set
ABL1	P00519	human	MYLK	Q15746	Y846	DGGGSDRyGsLRPGW
ABL1	P00519	human	PIK3AP1	Q6ZUJ8	Y594	DRPQssIyDPFAGMk
ABL1	P00519	human	GPX1	P07203	Y98	EILNSLkyVRPGGGF	GSHPx
ABL1	P00519	human	SRCIN1	Q9C0H9	Y396	LVKGEGLyADPyGLL
ABL1	P00519	human	NOS3	P29474	Y81	WEVGSITyDTLSAQA
ABL1	P00519	human	DCBLD2	Q96PD2	S760	PQStQEVsGAGRDGE
ABL1	P00519	human	MDM4	O15151	Y99	VkDPsPLyDMLRKNL
ABL1	P00519	human	HIPK2	Q9H2X6	Y367	tyLQsRYyRAPEIIL	Pkinase
ABL1	P00519	human	TRIM33	Q9UPN9	Y1048	MMKVVQVyADtQEIN	Bromodomain
ABL1	P00519	human	TBX21	Q9UL17	Y220	SMPGNRLyVHPDSPN	T-box
ABL1	P00519	human	PSMA7	O14818	Y106	EDPVTVEyItRyIAS	Proteasome
ABL1	P00519	human	PPARG	P37231	Y78	SSISTPHyEDIPFTR	PPARgamma_N
ABL1	P00519	human	ATR	Q13535	Y291	DTDQLKLyEEPLSkL
ABL1	P00519	human	DCBLD2	Q96PD2	Y649	EEGKEAGyADLDPyN
ABL1	P00519	human	AHSA1	O95433	Y223	LtsPEELyRVFTTQE	AHSA1
ABL1	P00519	human	DCBLD1	Q8N8Z6	Y589	QRAGRHEyALPLAPP
ABL1	P00519	human	DNM1L	O00429	Y266	TDSIRDEyAFLQkkY	Dynamin_M
ABL1	P00519	human	LGALS3	P17931	Y107	AYPATGPyGAPAGPL
ABL1	P00519	human	LGALS3	P17931	Y79	GAPAPGVyPGPPSGP
ABL1	P00519	human	DCBLD1	Q8N8Z6	Y600	LAPPEPEyAtPIVER
ABL1	P00519	human	WASF3	Q9UPY6	Y486	SRRIAVEySDSDDDS
ABL1	P00519	human	DCBLD1	Q8N8Z6	S556	GTVTRKGsTFRPMDT
ABL1	P00519	human	ESR2	Q92731	Y36	SIYIPSSyVDSHHEY	ERbeta_N
ABL1	P00519	human	RAD51	Q06609	Y54	HTVEAVAyAPkkELI	HHH_5
ABL1	P00519	human	EGFR	P00533	Y1197	stAENAEyLRVAPQS
ABL1	P00519	human	GLO1	Q04760	Y136	GIAVPDVysACkRFE	Glyoxalase
ABL1	P00519	human	STX17	P56962	Y157	SQSLTQIyALPEIPQ
ABL1	P00519	human	PPARG	P37231	Y102	yDLKLQEyQSAIkVE	PPARgamma_N
ABL1	P00519	human	GMNN	O75496	Y150	EVAEHVQyMAELIER	Geminin
ABL1	P00519	human	SNCA	P37840	Y39	kTkEGVLyVGsKTkE	Synuclein
ABL1	P00519	human	NFKBIA	P25963	Y305	FtEDELPyDDCVFGG
ABL1	P00519	human	MUC1	P15941	Y1243	NGGSsLsytNPAVAA
ABL1	P00519	human	DCBLD1	Q8N8Z6	S693	PPTHPGTsDsysAPR
ABL1	P00519	human	SORBS2	O94875-2	Y573	NTKGAEDyPDPPIPH
ABL1	P00519	human	ERRFI1	Q9UJM3	Y394	KKVsstHyyLLPERP
ABL1	P00519	human	CAV1	Q03135	Y14	VDsEGHLytVPIREQ
ABL1	P00519	human	RAD51	Q06609	Y315	EtRICKIyDSPCLPE	Rad51
ABL1	P00519	human	FOXA1	P55317	Y464	PAYYQGVySRPVLNT
ABL1	P00519	human	RTCB	Q9Y3I0	Y316	GMAAAGNyAWVNRSS	RtcB
ABL1	P00519	human	ESR1	P03372	Y52	DssKPAVyNYPEGAA	Oest_recep
ABL1	P00519	human	ATR	Q13535	Y310	FPFEAEAyRNIEPVY
ABL1	P00519	human	BCR	P11274	Y177	ADAEKPFyVNVEFHH
ABL1	P00519	human	PLCG1	P19174	Y1003	KGKKFLQyNRLQLSR	PI-PLC-Y
ABL1	P00519	human	MET	P08581	Y1356	yVHVNAtyVNVKCVA
ABL1	P00519	human	BTK	Q06187	Y223	LKKVVALyDyMPMNA	SH3_1
ABL1	P00519	human	EGFR	P00533	Y1016	DVVDADEyLIPQQGF
ABL1	P00519	human	RACK1	P63244	Y52	LtrDEtNyGIPQRAL
ABL1	P00519	human	SORBS2	O94875-2	Y175	YTYNAGLyNPPYSAQ
ABL1	P00519	human	ABL2	P42684	Y261	GLVTTLHyPAPKCNK
ABL1	P00519	human	STK3	Q13188	Y81	MQQCDSPyVVKYYGS	Pkinase
ABL1	P00519	human	PLCG1	P19174	Y771	IGtAEPdyGALyEGR
ABL1	P00519	human	PLK1	P53350	Y217	tLCGtPNyIAPEVLs	Pkinase
ABL1	P00519	human	SNW1	Q13573	Y292	AKLAEALyIADRKAR	SKIP_SNW
ABL1	P00519	human	PIK3AP1	Q6ZUJ8	Y570	QERPGNFyVSSEsIR
ABL1	P00519	human	CEBPB	P17676	Y78	RAIDFsPyLEPLGAP
ABL1	P00519	human	DCBLD1	Q8N8Z6	Y540	ITsDMADyQQPLMIG
ABL1	P00519	human	OTULIN	Q96BN8	Y56	AEHEEDMyRAADEIE
ABL1	P00519	human	JUN	P05412	Y170	LHSEPPVyANLSNFN	Jun
ABL1	P00519	human	IRF3	Q14653	Y292	rLGHCHTyWAVSEEL	IRF-3
ABL1	P00519	human	DCBLD2	Q96PD2	Y597	HEEtPVRysssEVNH
ABL1	P00519	human	DCBLD2	Q96PD2	Y621	LQADsAEyAQPLVGG
ABL1	P00519	human	CTTN	Q14247	Y486	yPAEDStyDEYENDL
ABL1	P00519	human	TP63	Q9H3D4	Y171	AIPSNTDyPGPHSFD	P53
ABL1	P00519	human	NCOA3	Q9Y6Q9	Y1357	HPQAASIyQSSEMKG
ABL1	P00519	human	RBM39	Q14498	Y95	DRRFRGRyrsPysGP
ABL1	P00519	human	SNW1	Q13573	Y433	EDEIyNVyDQAWrGG
ABL1	P00519	human	EMD	P50402	Y167	AyQsItHyRPVsAsR
ABL1	P00519	human	DCBLD2	Q96PD2	T679	ITGPEyAtPIIMDMS
ABL1	P00519	human	NCK1	P16333	Y105	VDPGERLyDLNMPAy
ABL1	P00519	human	PIK3AP1	Q6ZUJ8	Y694	AKVEFGVyEsGPRKs
ABL1	P00519	human	DCBLD2	Q96PD2	Y677	LPITGPEyAtPIIMD
ABL1	P00519	human	CAT	P04040	Y386	yRARVANyQRDGPMC	Catalase
ABL1	P00519	human	RAD52	P43351	Y104	DLNNGKFyVGVCAFV	Rad52_Rad22
ABL1	P00519	human	ROBO1	Q9Y6N7	Y1114	QEVAPVQyNIVEQNk
ABL1	P00519	human	YAP1	P46937-3	Y357	SGLSMSSySVPRtPD
ABL1	P00519	human	WASF3	Q9UPY6	Y337	LPAQIIEyYNPSGPP
ABL1	P00519	human	DDX5	P17844	Y593	NGMNQQAyAyPATAA
ABL1	P00519	human	DCBLD1	Q8N8Z6	S513	yPFARHQsAEFtISY
ABL1	P00519	human	PLK1	P53350	Y425	SDkYGLGyQLCDNSV	POLO_box
ABL1	P00519	human	DCBLD2	Q96PD2	S618	TTVLQADsAEyAQPL
ABL1	P00519	human	CDC73	Q6P1J9	Y290	kQPIPAAyNRyDQER	CDC73_N
ABL1	P00519	human	ARHGDIB	P52566	Y24	ELdskLNykPPPQks	Rho_GDI
ABL1	P00519	human	TBX21	Q9UL17	Y266	VLQsLHKyQPRLHIV	T-box
ABL1	P00519	human	MYLK	Q15746	Y1635	VAPEVINyEPIGYAT	Pkinase
ABL1	P00519	human	JUNB	P17275	Y188	VyTNLSSySPASASS	Jun
ABL1	P00519	human	DCBLD2	Q96PD2	Y666	GQEVyHAyAEPLPIT
ABL1	P00519	human	PIK3AP1	Q6ZUJ8	Y553	QLPDNEPyIFKVFAE
ABL1	P00519	human	GMFG	O60234	Y104	kPEQQMMyAGSkNRL	Cofilin_ADF
ABL1	P00519	human	SRCIN1	Q9C0H9	Y264	IYRKEPLyAAFPGSH	AIP3
ABL1	P00519	human	PSMA7	O14818	Y153	QTDPsGtyHAWkANA	Proteasome
ABL1	P00519	human	TRIM33	Q9UPN9	Y524	QHMQQQVyAQKHQQL
ABL1	P00519	human	CDKN1B	P46527	Y89	GsLPEFyyRPPRPPK
ABL1	P00519	human	NUMA1	Q14980	Y1774	VEsLEsLyFtPIPAR
ABL1	P00519	human	DCBLD1	Q8N8Z6	Y578	STDAGGHyDCPQRAG
ABL1	P00519	human	CRK	P46108	Y251	QKRVPNAyDktALAL	SH3_2
ABL1	P00519	human	DNM1L	O00429	Y368	CGGARICyIFHETFG	Dynamin_M
ABL1	P00519	human	ZNF746	Q6NUN9	Y137	ETLVSLDyAISKPEV
ABL1	P00519	human	DCBLD2	Q96PD2	T593	kAVDHEEtPVRysss
ABL1	P00519	human	TUBG1	P23258	Y443	HAATRPDyISWGTQE
ABL1	P00519	human	PLEKHG2	Q9H7P9	Y489	sEPVKDPyVMFPQNA
ABL1	P00519	human	DDB1	Q16531	Y182	APTICFVyQDPQGRH	MMS1_N
ABL1	P00519	human	SORBS2	O94875-2	Y50	AVSPMSYyQRPFSPS
ABL1	P00519	human	LGALS3	P17931	Y118	AGPLIVPyNLPLPGG	Gal-bind_lectin
ABL1	P00519	human	PRAG1	Q86YV5	Y413	ATQPEPIyAEsTKRK
ABL1	P00519	human	MYLK	Q15746	Y611	KSSRkSEyLLPVAPS
ABL1	P00519	human	CTNNB1	P35222	Y489	QNAVRLHyGLPVVVk
ABL1	P00519	human	CTNNB1	P35222	Y654	RNEGVAtyAAAVLFR
ABL1	P00519	human	SORBS2	O94875-2	Y164	PDDDTDMyNTPYTYN
ABL1	P00519	human	DNM1L	O00429	Y449	IIQHCSNySTQELLR	Dynamin_M
ABL1	P00519	human	PLSCR1	O15162	Y74	PVyNQPVyNQPVGAA
ABL1	P00519	human	ERCC6	Q03468	Y932	GANRVVIyDPDWNPS	Helicase_C
ABL1	P00519	human	DCBLD2	Q96PD2	T714	QPPPLVGtyNtLLsR
ABL1	P00519	human	PRKN	O60260	Y143	sPAGRSIyNSFYVYC
ABL1	P00519	human	MYLK	Q15746	Y556	LNGQPIQyARSTCEA	I-set
ABL1	P00519	human	SNW1	Q13573	Y430	AGGEDEIyNVyDQAW
ABL1	P00519	human	FHL2	Q14192	Y97	TDCySNEySSkCQEC	LIM
ABL1	P00519	human	RAD9A	Q99638	Y28	SRIGDELyLEPLEDG	Rad9
ABL1	P00519	human	SPTLC1	O15269	Y164	KTEEAIIySYGFATI	Aminotran_1_2
ABL1	P00519	human	MAVS	Q7Z434	Y71	RRPGWVEyFIAALRG	CARD_2
ABL1	P00519	human	CHCHD2	Q9Y6H1	Y99	PARPDITyQEPQGTQ
ABL1	P00519	human	STK4	Q13043	Y433	kIPQDGDyEFLksWt	Mst1_SARAH
ABL1	P00519	human	PDGFRB	P09619	Y934	AHAsDEIyEIMQKCW	PK_Tyr_Ser-Thr
ABL1	P00519	human	RBM39	Q14498	Y99	RGRyrsPysGPkFNs
ABL1	P00519	human	NFAT5	O94916	Y143	PkRHtVLyIsPPPED
ABL1	P00519	human	DCBLD2	Q96PD2	Y663	NsPGQEVyHAyAEPL
ABL1	P00519	human	ERRFI1	Q9UJM3	Y395	KVsstHyyLLPERPP
ABL1	P00519	human	TRIM33	Q9UPN9	Y610	PrHSGPQySMMQPHL
ABL1	P00519	human	WASF3	Q9UPY6	Y248	HASDVtDySYPATPN
ABL1	P00519	human	HDAC2	Q92769	Y222	IGAGkGkyYAVNFPM	Hist_deacetyl
ABL1	P00519	human	FHL2	Q14192	Y236	SGLGGTkyIsFEERQ	LIM
ABL1	P00519	human	ROBO1	Q9Y6N7	Y1073	PSGQPTPyAtTQLIQ
ABL1	P00519	human	MYLK	Q15746	Y1575	QISEGVEyIHKQGIV	Pkinase
ABL1	P00519	human	PDHA1	P08559	Y301	MsDPGVsyRtREEIQ	E1_dh
ABL1	P00519	human	MDM2	Q00987	Y276	sDEDDEVyQVtVyQA
ABL1	P00519	human	RTCB	Q9Y3I0	Y306	AsPEGQDyLkGMAAA	RtcB
ABL1	P00519	human	PDK1	Q15118	Y243	ARRLCDLyyINSPEL
ABL1	P00519	human	FUS	P35637	Y526	QDrrErPy_______
ABL1	P00519	human	FHL2	Q14192	Y217	LNCFCDLyAKkCAGC	LIM
ABL1	P00519	human	DCBLD2	Q96PD2	S599	EtPVRysssEVNHLs
ABL1	P00519	human	MDM2	Q00987	Y405	STSSSIIyssQEDVK
ABL1	P00519	human	DCBLD1	Q8N8Z6	Y621	tFsAQsGyRVPGPQP
ABL1	P00519	human	DCBLD1	Q8N8Z6	Y696	HPGTsDsysAPRDCL
ABL1	P00519	human	LASP1	Q14847	Y171	IPtsAPVyQQPQQQP
ABL1	P00519	human	PRKD1	Q15139	Y463	NDTGsRYyKEIPLSE	PH
ABL1	P00519	human	YY1	P25490	Y254	sPPDySEyMTGkKLP
ABL1	P00519	human	ARHGDIB	P52566	Y130	LkYVQHtyRTGVkVD	Rho_GDI
ABL1	P00519	human	DDB1	Q16531	Y718	HIRtVPLyEsPRkIC
ABL1	P00519	human	WAS	P42768	Y291	AEtsKLIyDFIEDQG	PBD
ABL1	P00519	human	CKMT1B	P12532	Y153	AsKIRsGyFDErYVL
ABL1	P00519	human	DCBLD1	Q8N8Z6	S535	QkLDLITsDMADyQQ
ABL1	P00519	human	KAT5	Q92993	Y44	ISGRKLFyVHYIDFN	Tudor-knot
ABL1	P00519	human	MAVS	Q7Z434	Y9	PFAEDkTykyICRNF	CARD_2
ABL1	P00519	human	RTCB	Q9Y3I0	Y475	MEEAPESykNVTDVV	RtcB
ABL1	P00519	human	DCBLD1	Q8N8Z6	Y652	VGAQDGDyQRPHsAQ
ABL1	P00519	human	TOP1	P11387	Y268	AkMLDHEyTTkEIFR	Topoisom_I_N
ABL1	P00519	human	SMAD4	Q13485	Y322	SNHPAPEyWCSIAYF
ABL1	P00519	human	VAV1	P15498	Y267	TPGAANLyQVFIKYK	RhoGEF
BCR	P11274	human	YWHAQ	P27348	S232	LTLWtsDsAGEECDA
BCR	P11274	human	YWHAZ	P63104	T232	LTLWtsDtQGDEAEA
BCR	P11274	human	AFDN	P55196	T909	VVTVAENtADELARS

Biological Network Integration of This Kinase and Substrates (GeneMANIA website)

Enriched GO biological processes of the phosphorylation target genes of the kinase

Kinase	GOID	GO term	P.adjust
ABL1	ID	Description	0.00e+00
ABL1	GO:0097193	intrinsic apoptotic signaling pathway	2.05e-15
ABL1	GO:0062197	cellular response to chemical stress	1.46e-14
ABL1	GO:0034599	cellular response to oxidative stress	9.05e-12
ABL1	GO:2001233	regulation of apoptotic signaling pathway	1.04e-10
ABL1	GO:0006979	response to oxidative stress	1.04e-10
ABL1	GO:0030522	intracellular receptor signaling pathway	1.04e-10
ABL1	GO:0050673	epithelial cell proliferation	2.35e-10
ABL1	GO:0000302	response to reactive oxygen species	4.09e-10
ABL1	GO:0072331	signal transduction by p53 class mediator	6.46e-10
ABL1	GO:0032355	response to estradiol	8.39e-10
ABL1	GO:0042770	signal transduction in response to DNA damage	1.51e-09
ABL1	GO:0032970	regulation of actin filament-based process	1.94e-09
ABL1	GO:1902903	regulation of supramolecular fiber organization	2.61e-09
ABL1	GO:0032956	regulation of actin cytoskeleton organization	2.61e-09
ABL1	GO:0050678	regulation of epithelial cell proliferation	5.06e-09
ABL1	GO:0002757	immune response-activating signaling pathway	6.54e-09
ABL1	GO:0051098	regulation of binding	6.54e-09
ABL1	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	1.06e-08
ABL1	GO:0002764	immune response-regulating signaling pathway	1.42e-08
ABL1	GO:0034614	cellular response to reactive oxygen species	1.67e-08
ABL1	GO:0031334	positive regulation of protein-containing complex assembly	2.17e-08
ABL1	GO:0061614	miRNA transcription	4.65e-08
ABL1	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	5.89e-08
ABL1	GO:1902905	positive regulation of supramolecular fiber organization	6.15e-08
ABL1	GO:0010212	response to ionizing radiation	6.56e-08
ABL1	GO:0010586	miRNA metabolic process	6.96e-08
ABL1	GO:0031400	negative regulation of protein modification process	7.69e-08
ABL1	GO:0048144	fibroblast proliferation	7.79e-08
ABL1	GO:2001242	regulation of intrinsic apoptotic signaling pathway	1.31e-07
ABL1	GO:0051090	regulation of DNA-binding transcription factor activity	1.86e-07
ABL1	GO:2000628	regulation of miRNA metabolic process	1.86e-07
ABL1	GO:0010517	regulation of phospholipase activity	1.86e-07
ABL1	GO:0048145	regulation of fibroblast proliferation	2.43e-07
ABL1	GO:0001933	negative regulation of protein phosphorylation	2.59e-07
ABL1	GO:0043254	regulation of protein-containing complex assembly	2.59e-07
ABL1	GO:0051099	positive regulation of binding	3.27e-07
ABL1	GO:0009314	response to radiation	3.32e-07
ABL1	GO:0045936	negative regulation of phosphate metabolic process	4.34e-07
ABL1	GO:0010563	negative regulation of phosphorus metabolic process	4.38e-07
ABL1	GO:0048732	gland development	5.01e-07
ABL1	GO:0042326	negative regulation of phosphorylation	5.46e-07
ABL1	GO:0098781	ncRNA transcription	5.46e-07
ABL1	GO:1902893	regulation of miRNA transcription	5.58e-07
ABL1	GO:0030330	DNA damage respons	1.01e-08
ABL1	GO:2001235	positive regulation of apoptotic signaling pathway	9.26e-07
ABL1	GO:0033673	negative regulation of kinase activity	1.19e-06
ABL1	GO:0060191	regulation of lipase activity	1.19e-06
ABL1	GO:0010332	response to gamma radiation	1.20e-06
ABL1	GO:0051091	positive regulation of DNA-binding transcription factor activity	1.28e-06

Top

Related Drugs to BCR_ABL1

Drugs used for this fusion-positive patient. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene	Tgene	Drug	Source	PMID
BCR	ABL1	Imatinib	PubMed	32000382
BCR	ABL1	Dasatinib	MyCancerGenome
BCR	ABL1	Bosutinib	MyCancerGenome
BCR	ABL1	Nilotinib	MyCancerGenome
BCR	ABL1	Imatinib	MyCancerGenome
BCR	ABL1	Ponatinib	MyCancerGenome

Distribution of the number of studies mentioning BCR-ABL1 and kinase inhibitors the PubMed Abstract (04-01-2024)

Fusion gene - drug pair 1	Fusion gene - drug pair 2	PMID	Publication date	DOI	Study title
BCR-ABL1 AND Imatinib		38294463	2011-12-16	10.1002/9780470571224.pse460	Tyrosine kinase inhibitors for chronic myeloid leukemia
BCR-ABL1 AND Imatinib		37643857	2023-8	10.1136/bmjopen-2022-066361	Safety and efficacy of Vitamin D(3) supplementation with Imatinib in Chronic Phase- Chronic Myeloid Leukaemia: an Exploratory Randomized Controlled Trial.
BCR-ABL1 AND Imatinib		37632689	2023-08-26	10.1007/s12098-023-04782-8	"Philadelphia Chromosome Positive and Philadelphia-Like Acute Lymphoblastic Leukemia in Children and Adolescents: Current Management, Controversies and Emerging Concepts."
BCR-ABL1 AND Imatinib		37147192	2023-5	10.1016/j.transproceed.2023.03.058	A Case Report of Successful Kidney Transplantation in a Patient With Chronic Myelogenous Leukemia (CML) Who Has Been in Remission for 15 Years on Imatinib.
BCR-ABL1 AND Imatinib		37137346	2023-7	10.1016/j.micpath.2023.106115	Community detection in Epstein-Barr virus associated carcinomas and role of tyrosine kinase in etiological mechanisms for oncogenesis.
BCR-ABL1 AND Imatinib		36959211	2023-03-24	10.1038/s41392-023-01327-5	Imatinib blocks tyrosine phosphorylation of Smad4 and restores TGF-? growth-suppressive signaling in BCR-ABL1-positive leukemia.
BCR-ABL1 AND Imatinib		36681201	2023-2	10.1016/j.bmcl.2023.129144	Synthesis and biological evaluation of novel aromatic amide derivatives as potential BCR-ABL inhibitors.
BCR-ABL1 AND Imatinib		36676983	2022-12-30	10.3390/metabo13010058	Curcumin Decreases Viability and Inhibits Proliferation of Imatinib-Sensitive and Imatinib-Resistant Chronic Myeloid Leukemia Cell Lines.
BCR-ABL1 AND Imatinib		36535407	2023-2	10.1016/j.exphem.2022.12.003	miR-495-3p sensitizes BCR-ABL1-expressing leukemic cells to tyrosine kinase inhibitors by targeting multidrug resistance 1 gene in T315I mutated cells.
BCR-ABL1 AND Imatinib		36281590	1905-06-22	10.2169/naika.89.353	The Evolution of the Treatment of Chronic Myelogenous Leukemia
BCR-ABL1 AND Imatinib		36258734	2022-04-11	10.1007/s12288-022-01532-2	OCT-1 Expression in Patients with Chronic Myeloid Leukemia: A Comparative Analysis with Respect to Response to Imatinib Treatment.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Ponatinib	36213346	2022-9	10.1016/j.jaccao.2022.06.004	Involvement of Rho-Associated Coiled-Coil Containing Kinase (ROCK) in�BCR-ABL1 Tyrosine Kinase Inhibitor Cardiovascular Toxicity.
BCR-ABL1 AND Imatinib		36091760	2022-08-25	10.3389/fphar.2022.952250	Anticancer potential of mebendazole against chronic myeloid leukemia: in silico and in vitro studies revealed new insights about the mechanism of action.
BCR-ABL1 AND Imatinib		35887063	2022-07-13	10.3390/ijms23147715	Ketoconazole Reverses Imatinib Resistance in Human Chronic Myelogenous Leukemia K562 Cells.
BCR-ABL1 AND Imatinib		35782581	1905-07-14	10.1016/j.lrr.2022.100333	"AML with BCR-ABL1 Fusion treated with Imatinib, a Hypomethylating Agent and Venetoclax."
BCR-ABL1 AND Imatinib		35625893	2022-05-17	10.3390/biomedicines10051158	Combination of Elacridar with Imatinib Modulates Resistance Associated with Drug Efflux Transporters in Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		35411807	2022-6	10.2217/cer-2022-0032	Burden of tyrosine kinase inhibitor failure in Chinese chronic myeloid leukemia patients: a systematic literature review.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	35370687	2022-03-18	10.3389/fphar.2022.862504	Mechanistic Insights Into Co-Administration of Allosteric and Orthosteric Drugs to Overcome Drug-Resistance in T315I BCR-ABL1.
BCR-ABL1 AND Imatinib		35337107	2022-03-03	10.3390/ph15030309	"Hybrids of Imatinib with Quinoline: Synthesis, Antimyeloproliferative Activity Evaluation, and Molecular Docking."
BCR-ABL1 AND Imatinib		35313299	1905-07-14	10.1159/000524158	MiR-199a-3p Overexpression Suppressed Cell Proliferation and Sensitized Chronic Myeloid Leukaemia Cells to Imatinib by Inhibiting mTOR Signalling.
BCR-ABL1 AND Imatinib		35154624	2020-11-05	10.1182/blood-2020-139531	Contemporary practice patterns of tyrosine kinase inhibitor use among older patients with chronic myeloid leukemia in the United States.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Dasatinib	35083382	2022-01-07	10.1253/circrep.cr-21-0140	Comparison of Dasatinib- and Imatinib-Related Cardiotoxic Adverse Events in Japanese Patients With Chronic Myeloid Leukemia and Gastrointestinal Stromal Tumor.
BCR-ABL1 AND Imatinib		34781898	2021-11-15	10.1186/s10020-021-00395-z	Global identification of circular RNAs in imatinib (IM) resistance of chronic myeloid leukemia (CML) by modulating signaling pathways of circ_0080145/miR-203/ABL1 and circ 0051886/miR-637/ABL1.
BCR-ABL1 AND Imatinib		34685486	2021-09-22	10.3390/cells10102506	DNA Fingerprint Analysis of Raman Spectra Captures Global Genomic Alterations in Imatinib-Resistant Chronic Myeloid Leukemia: A Potential Single Assay for Screening Imatinib Resistance.
BCR-ABL1 AND Imatinib		34638557	2021-09-23	10.3390/ijms221910216	MiR-125a-3p and MiR-320b Differentially Expressed in Patients with Chronic Myeloid Leukemia Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Imatinib Mesylate.
BCR-ABL1 AND Imatinib		34638304	2021-09-26	10.3390/cancers13194820	Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia-From Molecular Mechanisms to Clinical Relevance.
BCR-ABL1 AND Imatinib		34625105	2021-10-08	10.1186/s13256-021-03060-5	Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia with e1a3 BCR-ABL1 transcript in a Nigerian with sickle cell anemia: a case report.
BCR-ABL1 AND Imatinib		34439257	2021-08-15	10.3390/cancers13164102	Discontinuation of Imatinib in Children with Chronic Myeloid Leukemia: A Study from the International Registry of Childhood CML.
BCR-ABL1 AND Imatinib		34428479	2021-10	10.1016/j.jconrel.2021.08.035	Imatinib co-loaded targeted realgar nanocrystal for synergistic therapy of chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		34300312	2021-07-16	10.3390/jcm10143146	"Impact of BCR-ABL1 Transcript Type on Response, Treatment-Free Remission Rate and Survival in Chronic Myeloid Leukemia Patients Treated with Imatinib."
BCR-ABL1 AND Imatinib		34292760	2021-12	10.1200/go.21.00058	Spectrum of BCR-ABL Mutations and Treatment Outcomes in Ethiopian Imatinib-Resistant Patients With Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		34275666	2022-1	10.1016/j.arcmed.2021.06.003	Alterations in Sialylation Patterns are Significantly Associated with Imatinib Mesylate Resistance in Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		33924068	2021-04-20	10.3390/biom11040610	Relationship between Oxidative Stress and Imatinib Resistance in Model Chronic Myeloid Leukemia Cells.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	33903307	2019-04-19	10.1136/jclinpath-2019-205799	H396P mutation in chronic myeloid leukaemia patient on nilotinib - A case report.
BCR-ABL1 AND Imatinib		33893334	2021-04-23	10.1038/s41598-021-86875-y	Predictive value of tyrosine phosphatase receptor gamma for the response to treatment tyrosine kinase inhibitors in chronic myeloid leukemia patients.
BCR-ABL1 AND Imatinib		33517185	2021-2	10.1016/j.leukres.2021.106516	MR 4log and low levels of NK cells are associated with higher molecular relapse after imatinib discontinuation: Results of a prospective trial.
BCR-ABL1 AND Imatinib		33470551	2021-01-20	10.1111/ijlh.13471	Glutathione S-transferase gene polymorphic sequence variations: Association with risk and response to Imatinib among Chronic Myeloid Leukemia patients of Kashmir.
BCR-ABL1 AND Imatinib		33361712	2019-11-07	10.1007/s11899-019-00548-2	"Clinical implications of conventional cytogenetics, fluorescence in situ hybridization (FISH) and molecular testing in chronic myeloid leukaemia patients in the tyrosine kinase inhibitor era - A review."
BCR-ABL1 AND Imatinib		33100706	2020-02-25	10.1007/s12288-020-01264-1	Distribution of BCR-ABL1 Transcript Variants in Nigerians with Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Ponatinib	32972178	2020-06-01	10.36290/vnl.2020.064	Contemporary treatment methods of adult patients with BCR/ABL1 positive chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		32971032	2020-9	10.1016/j.hemonc.2020.08.003	Impact of the Major BCR-ABL1 Transcript Type on Clinical and Biological Parameters and Molecular Response in Patients With Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		32928796	2021-01-01	10.1158/1078-0432.ccr-20-1600	"Flumatinib versus Imatinib for Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia: A Phase III, Randomized, Open-label, Multi-center FESTnd Study."
BCR-ABL1 AND Imatinib		32910995	2020-10	10.1016/j.exphem.2020.09.186	Efficacy of tyrosine kinase inhibitors on a mouse chronic myeloid leukemia model and chronic myeloid leukemia stem cells.
BCR-ABL1 AND Imatinib		32699984	2019-08-08	10.1007/s40487-019-00098-w	Tyrosine Kinase Inhibitor Sequencing in Patients with Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		32697563	2020-8	10.1097/ftd.0000000000000771	Evaluation of Imatinib Concentrations in Samples Submitted for BCR-ABL1 or Imatinib Testing-Evidence to Support Therapeutic Drug Monitoring for Dose Optimization?
BCR-ABL1 AND Imatinib		32068648	2020-02-14	10.1097/mph.0000000000001743	B-Cell Precursor-Acute Lymphoblastic Leukemia With EBF1-PDGFRB Fusion Treated With Hematopoietic Stem Cell Transplantation and Imatinib: A Case Report and Literature Review.
BCR-ABL1 AND Imatinib		32068648	2020-02-14	10.1097/mph.0000000000001743	B-Cell Precursor-Acute Lymphoblastic Leukemia With EBF1-PDGFRB Fusion Treated With Hematopoietic Stem Cell Transplantation and Imatinib: A Case Report and Literature Review.
BCR-ABL1 AND Imatinib		32000382	2020-1	10.1097/md.0000000000018811	Atypical myeloproliferative neoplasm with concurrent BCR-ABL1 fusion and CALR mutation: A case report and literature review.
BCR-ABL1 AND Imatinib		31925317	2020-01-10	10.1038/s41375-019-0700-9	A randomised phase II trial of hydroxychloroquine and imatinib versus imatinib alone for patients with chronic myeloid leukaemia in major cytogenetic response with residual disease.
BCR-ABL1 AND Imatinib		33821851	1983-1	10.1213/00000539-198301000-00023	Outcomes of Jehovah's Witnesses with hematological malignancies treated without transfusions - single center experience.
BCR-ABL1 AND Imatinib		31540978	2019-11-15	10.1158/1078-0432.ccr-19-2270	ddeeper Than Deep: Can ddPCR Predict Successful Imatinib Cessation?
BCR-ABL1 AND Imatinib		31471409	1905-07-11	10.21873/invivo.11641	Successful Management of a Pregnant Patient With Chronic Myeloid Leukemia Receiving Standard Dose Imatinib.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Midostaurin	31431216	2019-08-21	10.2533/chimia.2019.561	"Investigations into the Potential Role of Metabolites on the Anti-Leukemic Activity of Imatinib, Nilotinib and Midostaurin."
BCR-ABL1 AND Imatinib		31423283	2019-06-21	10.3892/ol.2019.10518	Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro.
BCR-ABL1 AND Imatinib		31292142	2019-11-15	10.1158/1078-0432.ccr-18-3373	Evaluation of Residual Disease and TKI Duration Are Critical Predictive Factors for Molecular Recurrence after Stopping Imatinib First-line in Chronic Phase CML Patients.
BCR-ABL1 AND Imatinib		31245199	2019-04-09	10.7759/cureus.4411	Novel Score-based Decision Approach in Chronic Myeloid Leukemia Patients After Acute Toxic Imatinib-induced Liver Injury.
BCR-ABL1 AND Imatinib		31231484	2021-09-16	10.3324/haematol.2020.266155	Signaling pathways involved in chronic myeloid leukemia pathogenesis: The importance of targeting Musashi2-Numb signaling to eradicate leukemia stem cells.
BCR-ABL1 AND Imatinib		31122263	2019-05-23	10.1186/s13046-019-1197-9	Hyper-activation of Aurora kinase a-polo-like kinase 1-FOXM1 axis promotes chronic myeloid leukemia resistance to tyrosine kinase inhibitors.
BCR-ABL1 AND Imatinib		31079264	2019-05-11	10.1007/s00277-019-03706-x	Ten-year outcome of chronic-phase chronic myeloid leukemia patients treated with imatinib in real life.
BCR-ABL1 AND Imatinib		31073408	2019-05-02	10.1186/s12878-019-0139-2	Response to Imatinib therapy is inferior for e13a2 BCR-ABL1 transcript type in comparison to e14a2 transcript type in chronic myeloid leukaemia.
BCR-ABL1 AND Imatinib		31064152	2019-05-06	10.3390/ijms20092226	Clinical Implications of Discordant Early Molecular Responses in CML Patients Treated with Imatinib.
BCR-ABL1 AND Imatinib		31036317	2019-5	10.1016/s2352-3026(19)30027-4	Effect of low-level BCR-ABL1 kinase domain mutations identified by next-generation sequencing in patients with chronic myeloid leukaemia: a population-based study.
BCR-ABL1 AND Imatinib		31014357	2019-04-23	10.1186/s12964-019-0350-6	Imatinib independent aberrant methylation of NOV/CCN3 in chronic myelogenous leukemia patients: a mechanism upstream of BCR-ABL1 function?
BCR-ABL1 AND Imatinib		30911698	2019-6	10.1016/j.ajoc.2019.02.003	A unique case of chronic myeloid leukemia presenting as monocular vision loss with unilateral retinopathy.
BCR-ABL1 AND Imatinib		30687103	2019-01-09	10.3389/fphar.2018.01546	A Novel Naphthoquinone-Coumarin Hybrid That Inhibits BCR-ABL1-STAT5 Oncogenic Pathway and Reduces Survival in Imatinib-Resistant Chronic Myelogenous Leukemia Cells.
BCR-ABL1 AND Imatinib		30504658	2018-12-01	10.1248/yakushi.18-00142	MET/ERK and MET/JNK Pathway Activation Is Involved in BCR-ABL Inhibitor-resistance in Chronic Myeloid Leukemia
BCR-ABL1 AND Imatinib		31949592	1905-07-10	10.5070/d3245040040	Chronic myelogenous leukemia following small lymphocytic lymphoma: a case report and review of literature.
BCR-ABL1 AND Imatinib		30210745	2018-09-01	10.4084/mjhid.2018.052	The Spectrum of Hypereosinophilia and Associated Clonal Disorders - A Real-World Data Based on Combined Retrospective and Prospective Analysis from a Tropical Setting.
BCR-ABL1 AND Imatinib		30210745	2018-09-01	10.4084/mjhid.2018.052	The Spectrum of Hypereosinophilia and Associated Clonal Disorders - A Real-World Data Based on Combined Retrospective and Prospective Analysis from a Tropical Setting.
BCR-ABL1 AND Imatinib		30082224	2018-10	10.1016/j.clml.2018.06.031	Comparison of Frequency and Sensitivity of BCR-ABL1 Kinase Domain Mutations in Asian and White Patients With Imatinib-resistant Chronic-Phase Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		29967475	2018-07-02	10.1038/s41598-018-27767-6	T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Ponatinib	29946549	2018-06-12	10.3389/fcvm.2018.00055	"The BCR-ABL1 Inhibitors Imatinib and Ponatinib Decrease Plasma Cholesterol and Atherosclerosis, and Nilotinib and Ponatinib Activate Coagulation in a Translational Mouse Model."
BCR-ABL1 AND Imatinib		29808796	2018-05-15	10.14715/cmb/2018.64.6.5	Characterization of imatinib-resistant K562 cell line displaying resistance mechanisms.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Ponatinib	29742077	2002-6	10.1046/j.1468-0734.2002.00066.x	Philadelphia chromosome-positive acute lymphoblastic leukemia in adults: current treatments and future perspectives.
BCR-ABL1 AND Imatinib		29703870	1905-07-13	10.1007/978-3-030-71913-5_3	"The epidemiology of chronic myeloid leukaemia in southern Sarawak, Borneo Island."
BCR-ABL1 AND Imatinib		29483845	2018-02-20	10.1186/s12935-018-0523-1	MLL2/KMT2D and MLL3/KMT2C expression correlates with disease progression and response to imatinib mesylate in chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		29455643	2018-02-19	10.1186/s12943-018-0780-6	Chronic myeloid leukemia: the paradigm of targeting oncogenic tyrosine kinase signaling and counteracting resistance for successful cancer therapy.
BCR-ABL1 AND Imatinib		29200684	1905-07-09	10.4103/ijmpo.ijmpo_115_17	The Role of Mutation Testing in Patients with Chronic Myeloid Leukemia in Chronic Phase after Imatinib Failure and Their Outcomes after Treatment Modification: Single-institutional Experience Over 13 Years.
BCR-ABL1 AND Imatinib		29152155	2017-09-22	10.18632/oncotarget.21166	Chibby 1: a new component of ?-catenin-signaling in chronic myeloid leukemia.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Bosutinib	29091516	2018-01-20	10.1200/jco.2017.74.7162	Bosutinib Versus Imatinib for Newly Diagnosed Chronic Myeloid Leukemia: Results From the Randomized BFORE Trial.
BCR-ABL1 AND Imatinib		29032022	2017-12	10.1016/j.clml.2017.09.004	Outcomes of Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia Following an Elective Switch From Second-Generation Tyrosine Kinase Inhibitor to Imatinib.
BCR-ABL1 AND Imatinib		28939746	2017-11-30	10.1158/1078-0432.ccr-17-0957	Phase III Clinical Trial (RERISE study) Results of Efficacy and Safety of Radotinib Compared with Imatinib in Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		28847475	2017-12	10.1016/j.clml.2017.07.255	Outcomes of Chronic Myeloid Leukemia Patients With Early Molecular Response at 3 and 6 Months: A Comparative Analysis of Generic Imatinib and Glivec.
BCR-ABL1 AND Imatinib		28843219	1905-07-07	10.4103/0971-5916.164250	Molecular Response to Imatinib and Its Correlation with mRNA Expression Levels of Imatinib Influx Transporter (OCT1) in Indian Chronic Myeloid Leukemia Patients.
BCR-ABL1 AND Imatinib		28830599	2017-7	10.1016/j.bjhh.2017.04.007	Molecular response to imatinib mesylate of Brazilian patients with chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		28822797	2017-11	10.1016/j.clml.2017.06.009	Influence of BCR-ABL Transcript Type on Outcome in Patients With Chronic-Phase Chronic Myeloid Leukemia Treated With�Imatinib.
BCR-ABL1 AND Imatinib		28678800	2017-07-05	10.1371/journal.pone.0179700	Dynamical models of mutated chronic myelogenous leukemia cells for a post-imatinib treatment scenario: Response to dasatinib or nilotinib therapy.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Dasatinib	28657534	2022-09-11	10.48036/apims.v18i3.629	Mutations in the BCR-ABL1 gene in a peruvian patient with acute lymphoblastic leukemia resistant to therapy
BCR-ABL1 AND Imatinib		28627443	2017-9	10.1016/j.gene.2017.06.018	Impact of the BCR-ABL1 fusion transcripts on different responses to Imatinib and disease recurrence in Iranian patients with Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Ponatinib	28467002	2017-05-03	10.1111/bjh.14683	"The use of Imatinib resistance mutation analysis to direct therapy in Philadelphia chromosome/BCR-ABL1 positive chronic myeloid leukaemia patients failing Imatinib treatment, in Patan Hospital, Nepal."
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	28458002	2017-6	10.1016/j.jmgm.2017.04.005	In silico drug repurposing of FDA-approved drugs to predict new inhibitors for drug resistant T315I mutant and wild-type BCR-ABL1: A virtual screening and molecular dynamics study.
BCR-ABL1 AND Imatinib		28437552	1905-07-09	10.4238/gmr16029541	BCR-ABL1 transcript types showed distinct laboratory characteristics in patients with chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		28418880	2017-03-17	10.18632/oncotarget.16314	Contributions of MET activation to BCR-ABL1 tyrosine kinase inhibitor resistance in chronic myeloid leukemia cells.
BCR-ABL1 AND Imatinib		28369812	2017-03-29	10.1111/bjh.14645	"Treating Philadelphia chromosome/BCR-ABL1 positive patients with Glivec (Imatinib mesylate): 10�years' experience at Patan Hospital, Nepal."
BCR-ABL1 AND Imatinib		28325357	2017-4	10.1016/j.anndiagpath.2016.12.001	"Chronic myeloid leukemia with a rare fusion transcript, e19a2 BCR-ABL1: A report of three cases from India."
BCR-ABL1 AND Imatinib		28286862	2017-02-13	10.1155/2017/1076493	Consistency Test between Scoring Systems for Predicting Outcomes of Chronic Myeloid Leukemia in a Saudi Population Treated with Imatinib.
BCR-ABL1 AND Imatinib		28283298	2017-4	10.1016/j.clml.2017.02.001	The Efficacy of Generic Imatinib as First- and Second-line Therapy: 3-Year Follow-up of Patients With Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		28278078	2017-02-21	10.1080/15384047.2017.1294289	Presence of novel compound BCR-ABL mutations in late chronic and advanced phase imatinib sensitive CML patients indicates their possible role in CML progression.
BCR-ABL1 AND Imatinib		28273028	2017-03-09	10.1056/nejmoa1609324	Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		28253493	1905-07-08	10.1159/000458164	Isodicentric Philadelphia Chromosome: A Rare Chromosomal Aberration in Imatinib-Resistant Chronic Myelogenous Leukemia Patients - Case Report with Review of the Literature.
BCR-ABL1 AND Imatinib		28154092	2017-02-02	10.3324/haematol.2016.153270	Increased peroxisome proliferator-activated receptor ? activity reduces imatinib uptake and efficacy in chronic myeloid leukemia mononuclear cells.
BCR-ABL1 AND Imatinib		28093990	2017-03-31	10.2174/1389200218666170116113705	Insight to Pharmacokinetics of TKIs: Optimizing Practical Guidelines for Individualized Therapy.
BCR-ABL1 AND Imatinib		27908728	2017-1	10.1016/j.bbrc.2016.11.146	Activation of EVI1 transcription by the LEF1/?-catenin complex with p53-alteration in myeloid blast crisis of chronic myeloid leukemia.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	27821800	2016-11-03	10.18632/oncotarget.13035	Synergistic effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway or NUP214-ABL1 fusion protein in human Acute Lymphoblastic Leukemia.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	27821800	2016-11-03	10.18632/oncotarget.13035	Synergistic effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway or NUP214-ABL1 fusion protein in human Acute Lymphoblastic Leukemia.
BCR-ABL1 AND Imatinib		27721664	2016-1	10.4137/cmo.s32822	Is Adherence to Imatinib Mesylate Treatment Among Patients with Chronic Myeloid Leukemia Associated with Better Clinical Outcomes in Qatar?
BCR-ABL1 AND Imatinib		27485109	2016-08-02	10.1186/s12885-016-2635-0	"In chronic myeloid leukemia patients on second-line tyrosine kinase inhibitor therapy, deep sequencing of BCR-ABL1 at the time of warning may allow sensitive detection of emerging drug-resistant mutants."
BCR-ABL1 AND Imatinib		29097894	2019-02-01	10.12809/hkmj176972	Extranodal marginal zone B-cell lymphoma arising in chronic myeloid leukaemia successfully treated with tyrosine kinase inhibitor: a case report.
BCR-ABL1 AND Imatinib		27221912	2016-06-01	10.7314/apjcp.2016.17.4.2159	Diagnosis and Monitoring of Chronic Myeloid Leukemia: Chiang Mai University Experience.
BCR-ABL1 AND Imatinib		27220663	2016-05-25	10.1038/leu.2016.154	Effect of tyrosine kinase inhibitors on stemness in normal and chronic myeloid leukemia cells.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Dasatinib	27217448	2016-07-10	10.1200/jco.2015.64.8899	Final 5-Year Study Results of DASISION: The Dasatinib Versus Imatinib Study in Treatment-Na�ve Chronic Myeloid Leukemia Patients Trial.
BCR-ABL1 AND Imatinib		27167108	2016-05-05	10.18632/oncotarget.9182	Leukemic stem cell persistence in chronic myeloid leukemia patients in deep molecular response induced by tyrosine kinase inhibitors and the impact of therapy discontinuation.
BCR-ABL1 AND Imatinib		27161125	1905-07-08	10.1159/000444517	Overexpression of CCAAT Enhancer-Binding Protein ? Inhibits the Growth of K562 Cells via the Foxo3a-Bim Pathway.
BCR-ABL1 AND Imatinib		27160310	1905-07-08	10.1159/000444626	Medication Adherence to Tyrosine Kinase Inhibitors: 2-Year Analysis of Medication Adherence to Imatinib Treatment for Chronic Myeloid Leukemia and Correlation with the Depth of Molecular Response.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	27101984	2016-6	10.1016/j.clml.2016.03.003	Comparative Effectiveness of Newer Tyrosine Kinase Inhibitors Versus Imatinib in the First-Line Treatment of Chronic-Phase Chronic Myeloid Leukemia Across Risk Groups: A Systematic Review and Meta-Analysis of Eight Randomized Trials.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	26993758	2016-5	10.1016/j.clml.2016.02.002	Evaluating the Impact of a Switch to Nilotinib on Imatinib-Related Chronic Low-Grade Adverse Events in Patients With CML-CP: The ENRICH Study.
BCR-ABL1 AND Imatinib		26922746	2016-02-27	10.1007/s11899-016-0309-2	Long-Term Side Effects of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		26913392	2018-12-11	10.1002/jcb.28296	Overexpression of SHP-1 Enhances the Sensitivity of K562 Cells to Imatinib
BCR-ABL1 AND Imatinib		26910070	1905-07-08	10.1007/978-1-4939-3347-1_6	Dynamics of Expression of Drug Transporters: Methods for Appraisal.
BCR-ABL1 AND Imatinib		26819793	1905-07-07	10.1155/2015/380451	Isolated Ocular Manifestation of Relapsed Chronic Myelogenous Leukemia Presenting as Myeloid Blast Crisis in a Patient on Imatinib Therapy: A Case Report and Review of the Literature.
BCR-ABL1 AND Imatinib		26757169	2016-01-12	10.18388/abp.2015_1189	Mitochondrial mutagenesis in BCR-ABL1-expressing cells sensitive and resistant to imatinib.
BCR-ABL1 AND Imatinib		26695912	2016-12-02	10.1182/blood.v128.22.5453.5453	Assessment of response to imatinib therapy in patients with chronic myeloid leukemia with e13a2 and e14a2 transcripts of BCR/ABL1 gene.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	26664479	2017-02-28	10.1080/10428194.2017.1295145	The impact of additional cytogenetic abnormalities at diagnosis and during therapy with tyrosine kinase inhibitors in Chronic Myeloid Leukaemia.
BCR-ABL1 AND Imatinib		26646444	2016-3	10.1111/ped.12876	Optimal management for pediatric chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		26618175	1905-07-07	10.1155/2015/673512	"Doxorubicin Differentially Induces Apoptosis, Expression of Mitochondrial Apoptosis-Related Genes, and Mitochondrial Potential in BCR-ABL1-Expressing Cells Sensitive and Resistant to Imatinib."
BCR-ABL1 AND Imatinib		26615132	2015-12	10.1053/j.seminoncol.2015.09.030	Tyrosine Kinase Inhibitors Early in the Disease Course: Lessons From Chronic Myelogenous Leukemia.
BCR-ABL1 AND Imatinib		26435715	1905-07-07	10.1155/2015/908708	Determinants of Overall and Progression-Free Survival of Nigerian Patients with Philadelphia-Positive Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		26429162	1999-06-01	10.1038/sj.leu.2401426	Real-time quantitative PCR detection of WT1 and M-BCR-ABL expressions in chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		26371140	2015-12-10	10.1200/jco.2015.62.4718	Tyrosine Kinase Inhibitor-Associated Cardiovascular Toxicity in Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		26309809	2015-12	10.1089/biores.2015.0022	Reactive Oxygen Species and Mitochondrial DNA Damage and Repair in BCR-ABL1 Cells Resistant to Imatinib.
BCR-ABL1 AND Imatinib		26251899	2015-08-05	10.3390/ijms160818111	"UV Differentially Induces Oxidative Stress, DNA Damage and Apoptosis in BCR-ABL1-Positive Cells Sensitive and Resistant to Imatinib."
BCR-ABL1 AND Imatinib		26194865	2015-07-21	10.1007/s13277-015-3772-9	Inverse regulation of bridging integrator 1 and BCR-ABL1 in chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		26178642	2015-09-10	10.1002/ajh.24120	Age and dPCR can predict relapse in CML patients who discontinued imatinib: the ISAV study.
BCR-ABL1 AND Imatinib		26159458	1905-07-07	10.1159/000430835	BCR-ABL1 Transcript Levels at 3 and 6 Months Are Better for Identifying Chronic Myeloid Leukemia Patients with Poor Outcome in Response to Second-Line Second-Generation Tyrosine Kinase Inhibitors after Imatinib Failure: A Report from a Single Institution.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Dasatinib	26118315	2015-06-29	10.1038/leu.2015.168	BCR-ABL1 mutation development during first-line treatment with dasatinib or imatinib for chronic myeloid leukemia in chronic phase.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	25901138	2015-3	10.12816/0024688	Neutrophilic-chronic myeloid leukemia: A case report.
BCR-ABL1 AND Imatinib		25891192	2015-04-20	10.1111/bjh.13453	Long-term results of high-dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase: the Italian experience.
BCR-ABL1 AND Imatinib		25840461	2015-04-03	10.1517/14656566.2015.1031107	Which tyrosine-kinase inhibitor to use first in chronic phase chronic myelogenous leukemia?
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Ponatinib	25768408	2001-10-01	10.1182/blood.v98.7.2039	Integrating current treatment options for TKI-resistant chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		25696861	2014-12-05	10.1182/asheducation-2014.1.240	Prognostic significance of early molecular response in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors.
BCR-ABL1 AND Imatinib		25594053	2014-07-23	10.18632/oncoscience.65	Genomic quantitative real-time PCR proves residual disease positivity in more than 30% samples with negative mRNA-based qRT-PCR in Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		25519749	2015-02-05	10.1182/blood-2014-07-590315	TIDEL-II: first-line use of imatinib in CML with early switch to nilotinib for failure to achieve time-dependent molecular targets.
BCR-ABL1 AND Imatinib		25410137	2015-01-30	10.1002/ajh.23902	Molecular monitoring to improve outcomes in patients with chronic myeloid leukemia in chronic phase: importance of achieving treatment-free remission.
BCR-ABL1 AND Imatinib		25389112	2015-01-29	10.1002/jcb.25010	DNA methyltransferase 1 drives transcriptional down-modulation of ? catenin antagonist Chibby1 associated with the BCR-ABL1 gene of chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		25216532	2014-08-13	10.18632/oncotarget.2278	"Mapping of apoptin-interaction with BCR-ABL1, and development of apoptin-based targeted therapy."
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Dasatinib	24594142	2014-8	10.1016/j.clml.2014.01.003	Predicting outcomes in patients with chronic myeloid leukemia at any time during tyrosine kinase inhibitor therapy.
BCR-ABL1 AND Imatinib		24469953	2014-01-29	10.1007/s12032-014-0851-5	Reduced ABCG2 and increased SLC22A1 mRNA expression are associated with imatinib response in chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		24383843	2013-11-04	10.1111/bjh.12618	"Imatinib 800 mg daily induces deeper molecular responses than imatinib 400 mg daily: results of SWOG S0325, an intergroup randomized PHASE II trial in newly diagnosed chronic phase chronic myeloid leukaemia."
BCR-ABL1 AND Imatinib		24372965	2014-01-28	10.1111/ejh.12258	Imatinib and pegylated IFN-?2b discontinuation in first-line chronic myeloid leukemia patients following a major molecular response.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Dasatinib	24305542	2020-02-07	10.32388/diwods	Detection of BCR-ABL1 chimeric gene-positive neutrophils in a patient with mixed phenotype acute leukemia
BCR-ABL1 AND Imatinib		24008437	2013-09-04	10.1177/1066896913501382	Langerhans Cell Sarcoma in a Chronic Myelogenous Leukemia Patient Undergoing Imatinib Mesylate Therapy: A Case Study and Review of the Literature.
BCR-ABL1 AND Imatinib		23953880	2013-10	10.1016/j.leukres.2013.07.019	Imatinib induces demethylation of miR-203 gene: an epigenetic mechanism of anti-tumor effect of imatinib.
BCR-ABL1 AND Imatinib		23887971	2013-09-15	10.1158/0008-5472.can-13-1318	KIT signaling governs differential sensitivity of mature and primitive CML progenitors to tyrosine kinase inhibitors.
BCR-ABL1 AND Imatinib		23707389	2013-9	10.1016/j.cellsig.2013.05.019	Chibby drives ? catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1+ cells.
BCR-ABL1 AND Imatinib		23591360	2009-9	10.3816/clm.2009.s.016	Therapeutic strategies for childhood high-risk acute lymphoblastic leukemia
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Dasatinib	23278256	2012-11-16	10.1182/blood.v120.21.2777.2777	BCR-ABL1 transcript at 3 months predicts long-term outcomes following second generation tyrosine kinase inhibitor therapy in the patients with chronic myeloid leukaemia in chronic phase who failed Imatinib.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Dasatinib	26030291	2019-10-31	10.1007/978-3-319-95309-0_5013	MLL Rearrangment and EVI1 Deletion in BCR/ABL1 Positive Chronic Myeloid Leukemia.
BCR-ABL1 AND Imatinib		23212150	2012-12-05	10.1038/leu.2012.352	Randomized comparison of prophylactic and minimal residual disease-triggered imatinib after allogeneic stem cell transplantation for BCR-ABL1-positive acute lymphoblastic leukemia.
BCR-ABL1 AND Imatinib		22790637	2007-5	10.1016/j.leukres.2006.05.023	Late appearing Philadelphia chromosome as another clone in a patient with myelodysplastic syndrome harboring der(5;12)(q10;q10) at diagnosis
BCR-ABL1 AND Imatinib		22617440	2012-05-13	10.4161/auto.20053	microRNA 30A promotes autophagy in response to cancer therapy.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	22506320	2011-12	10.1016/j.cll.2011.08.012	Current therapy of chronic myeloid leukemia
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	22414011	2013-01-01	10.2174/156800913804486638	Multifaceted mechanisms for cell survival and drug targeting in chronic myelogenous leukemia.
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BCR-ABL1 AND Imatinib		22285507	2012-4	10.1016/j.leukres.2011.12.018	The study of resistant mechanisms and reversal in an imatinib resistant Ph+ acute lymphoblastic leukemia cell line.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	22252576	2009-12-03	10.1182/blood-2009-07-232595	Improving frontline treatment for chronic myeloid leukemia: emerging evidence for use of nilotinib and dasatinib.
BCR-ABL1 AND Imatinib		22248505	1905-07-04	10.1159/000334109	Prolonged survival with imatinib mesylate combined with chemotherapy and allogeneic stem cell transplantation in de novo Ph+ acute myeloid leukemia.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Ponatinib	22157290	2011-11	10.1097/ppo.0b013e31823dec8d	Evolution of therapies for chronic myelogenous leukemia.
BCR-ABL1 AND Imatinib		21732333	2011-07-05	10.1002/cncr.26225	The rise and fall of gatekeeper mutations? The BCR-ABL1 T315I paradigm.
BCR-ABL1 AND Imatinib		21693657	2011-08-11	10.1158/0008-5472.can-11-0068	Imatinib sensitivity in BCR-ABL1-positive chronic myeloid leukemia cells is regulated by the remaining normal ABL1 allele.
BCR-ABL1 AND Imatinib		21325259	2015-12-05	10.1182/asheducation-2015.1.406	A novel three-way Ph variant t(8;9;22) in adult acute lymphoblastic leukemia.
BCR-ABL1 AND Imatinib		21245758	2011-3	10.1097/moh.0b013e32834399ef	Mutational analysis in chronic myeloid leukemia: when and what to do?
BCR-ABL1 AND Imatinib		21138592	2010-12	10.1186/1471-2326-10-8	Patan hospital experience in treating philadelphia chromosome/BCR-ABL1 positive chronic myeloid leukemia patients with gleevec (imatinib mesylate); the first generation specific tyrosine kinase inhibitor.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	20806817	2003-02-01	10.2174/1389450033346885	"ABL1, SRC and other non-receptor protein tyrosine kinases as new targets for specific anticancer therapy"
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	20806817	2003-02-01	10.2174/1389450033346885	"ABL1, SRC and other non-receptor protein tyrosine kinases as new targets for specific anticancer therapy"
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BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	20017607	2009-12	10.3109/10428190903383427	Advances in treatment of chronic myelogenous leukemia--new treatment options with tyrosine kinase inhibitors.
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BCR-ABL1 AND Imatinib		19959082	2009-9	10.1016/j.beha.2009.08.001	Treatment strategies for CML.
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BCR-ABL1 AND Imatinib		19723306	2009-09-01	10.1186/1476-4598-8-69	MicroRNA expression profiling in Imatinib-resistant Chronic Myeloid Leukemia patients without clinically significant ABL1-mutations.
BCR-ABL1 AND Imatinib		19652654	2009-08-04	10.1038/nrclinonc.2009.112	Imatinib and beyond--exploring the full potential of targeted therapy for CML.
BCR-ABL1 AND Imatinib		19377081	2009-04-18	10.3324/haematol.2008.003715	The level of BCR-ABL1 kinase activity before treatment does not identify chronic myeloid leukemia patients who fail to achieve a complete cytogenetic response on imatinib.
BCR-ABL1 AND Imatinib		18323796	2008-03-06	10.1038/leu.2008.47	Experimental non-ATP-competitive therapies for chronic myelogenous leukemia.
BCR-ABL1 AND Imatinib	BCR-ABL1 AND Nilotinib	17701954	2007-08-31	10.1002/cncr.22881	Tyrosine kinase inhibitors for the treatment of Philadelphia chromosome-positive adult acute lymphoblastic leukemia.
BCR-ABL1 AND Imatinib		16683885	2006-05-01	10.5858/2006-130-669-iroao	Imatinib resistance: obstacles and opportunities.
BCR-ABL1 AND Imatinib		16205638	2005-10-03	10.1038/sj.onc.1209133	BCR-ABL1 induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cells.
BCR-ABL1 AND Imatinib		16079118	2021-10-11	10.1201/9781003120445-29	e6a2 BCR/ABL1 fusion with cryptic der(9)t(9;22) deletions in a patient with chronic myeloid leukemia.
BCR-ABL1 AND Imatinib	BCR-JAK2 AND Imatinib	16001431	2005-07-06	10.1002/gcc.20235	A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11.2) translocation in a patient with a clinically typical chronic myeloid leukemia.
BCR-ABL1 AND Imatinib		15254401	2004-7	10.4161/cc.3.7.991	Interference of BCR-ABL1 kinase activity with antigen receptor signaling in B cell precursor leukemia cells.
BCR-ABL1 AND Imatinib		15136244	2006-07-28	10.1002/cncr.22046	Complete molecular remission in a patient with Philadelphia-chromosome positive acute myeloid leukemia after conventional therapy and imatinib.
BCR-ABL1 AND Sorafenib		22513837	2012-04-19	10.1038/leu.2012.109	RET fusion genes are associated with chronic myelomonocytic leukemia and enhance monocytic differentiation.
BCR-ABL1 AND Dasatinib	BCR-ABL1 AND Ponatinib	37253456	2023-05-30	10.1097/ftd.0000000000001103	Cobicistat as a Potential Booster of Ponatinib and Dasatinib Exposure in a CML Patient: A Case Study.
BCR-ABL1 AND Dasatinib		36836615	2023-01-17	10.3390/life13020259	IGFBP-6 Alters Mesenchymal Stromal Cell Phenotype Driving Dasatinib Resistance in Chronic Myeloid Leukemia.
BCR-ABL1 AND Dasatinib		36605226	2022-12-05	10.1159/000527767	Successful Dasatinib Treatment of Epidermal Growth Factor Receptor-Mutant Lung Adenocarcinoma and BCR-ABL1-Positive Chronic Myeloid Leukemia: A Case Report.
BCR-ABL1 AND Dasatinib		36590661	2022-12	10.1002/ccr3.6807	Chronic myelogenous leukemia presenting with Morel Lavall�e lesion: A case report of a rare presentation.
BCR-ABL1 AND Dasatinib		36212403	2022-09-23	10.3389/fonc.2022.952640	Impact of genetic polymorphisms of drug transporters ABCB1 and ABCG2 and regulators of xenobiotic transport and metabolism PXR and CAR on clinical efficacy of dasatinib in chronic myeloid leukemia.
BCR-ABL1 AND Dasatinib		35842355	2022-9	10.1016/j.clml.2022.05.002	Efficacy and Safety of Generic Dasatinib in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase: A Multicenter Prospective Study in China.
BCR-ABL1 AND Dasatinib		35641028	2022-7	10.1016/j.jphs.2022.04.009	Dasatinib suppresses atherosclerotic lesions by suppressing cholesterol uptake in a mouse model of hypercholesterolemia.
BCR-ABL1 AND Dasatinib		34866085	2021-10-11	10.1201/9781003120445-29	Chronic myeloid leukemia with an in-frame exon 4 deletion in ABL1 with acute abdomen due to an intrapelvic bulky mass as the initial symptom
BCR-ABL1 AND Dasatinib		34824936	2021-10-25	10.7759/cureus.19024	Dasatinib-Induced Pleural and Pericardial Effusions.
BCR-ABL1 AND Dasatinib		34776414	2021-03-22	10.22541/au.161641901.15254184/v1	A narrative review on adverse effects of dasatinib with a focus on pharmacotherapy of dasatinib-induced pulmonary toxicities.
BCR-ABL1 AND Dasatinib		34492682	2021-11-18	10.1182/bloodadvances.2021004813	Dasatinib and dexamethasone followed by hematopoietic cell transplantation for adults with Ph-positive ALL.
BCR-ABL1 AND Dasatinib		34433624	2021-08-01	10.4049/immunohorizons.2100054	KIR3DL1 Allotype-Dependent Modulation of NK Cell Immunity against Chronic Myeloid Leukemia.
BCR-ABL1 AND Dasatinib		34413745	2021-07-19	10.1159/000517442	A Case of Tyrosine Kinase Inhibitor-Induced Bone Marrow Aplasia That Was Successfully Treated with Allogeneic Hematopoietic Stem Cell Transplantation.
BCR-ABL1 AND Dasatinib		34195988	2021-06-30	10.1111/bjh.17654	Dasatinib dose optimisation based on therapeutic drug monitoring reduces pleural effusion rates in chronic myeloid leukaemia patients.
BCR-ABL1 AND Dasatinib		34054462	2021-04-15	10.1159/000514632	A Case Report of BCR-ABL-JAK2-Positive Chronic Myeloid Leukemia with Complete Hematological and Major Molecular Response to Dasatinib.
BCR-ABL1 AND Dasatinib		33823073	2021-04-06	10.1002/cncr.33539	Outcome of patients with chronic myeloid leukemia in lymphoid blastic phase and Philadelphia chromosome-positive acute lymphoblastic leukemia treated with hyper-CVAD and dasatinib.
BCR-ABL1 AND Dasatinib		33814500	2021-10-01	10.2169/internalmedicine.7066-21	BCR/ABL1-positive B-lymphoblastic Lymphoma Successfully Treated with Dasatinib-combined Chemotherapy.
BCR-ABL1 AND Dasatinib		33732361	2021-02-12	10.3892/ol.2021.12546	"In vivo, ex vivo and in vitro dasatinib activity in chronic lymphocytic leukemia."
BCR-ABL1 AND Dasatinib		33672947	2021-02-14	10.3390/biology10020152	HHV8-Negative Effusion-Based Large B Cell Lymphoma Arising in Chronic Myeloid Leukemia Patients under Dasatinib Treatment: A Report of Two Cases.
BCR-ABL1 AND Dasatinib		33647814	2021-6	10.1016/j.cancergen.2021.02.007	BCR-ABL1 positive AML or CML in blast crisis? A pediatric case report with inv(3) and t(9;22) in the initial clone.
BCR-ABL1 AND Dasatinib		33407162	2021-01-06	10.1186/s12876-020-01584-6	Differential gene expression analysis of dasatinib-induced colitis in a patient with chronic myeloid leukemia followed for 3�years: a case report.
BCR-ABL1 AND Dasatinib		33157925	2020-11-06	10.1097/md.0000000000022791	Dasatinib associated lymphadenopathy in a chronic myeloid leukemia patient: A case report.
BCR-ABL1 AND Dasatinib		33021423	2020-10-06	10.1080/10428194.2020.1827242	Dasatinib treatment long-term results among imatinib-resistant/intolerant patients with chronic phase chronic myeloid leukemia are favorable in daily clinical practice.
BCR-ABL1 AND Dasatinib	BCR-ABL1 AND Bosutinib	32536651	2020-09-15	10.2169/internalmedicine.4714-20	Dasatinib-induced Nonspecific Interstitial Pneumonia That Developed 7 Years after the Initiation of Dasatinib.
BCR-ABL1 AND Dasatinib		32124237	2020-03-02	10.1007/s12012-020-09565-7	Mechanisms of the Cardiac Myocyte-Damaging Effects of Dasatinib.
BCR-ABL1 AND Dasatinib		31999839	2020-01-30	10.1002/cncr.32627	Long-term results of frontline dasatinib in chronic myeloid leukemia.
BCR-ABL1 AND Dasatinib		31553487	2019-09-25	10.1002/cncr.32504	Long-term follow-up of lower dose dasatinib (50�mg daily) as frontline therapy in newly diagnosed chronic-phase chronic myeloid leukemia.
BCR-ABL1 AND Dasatinib		31262926	2019-7	10.21873/anticanres.13548	Efficacy of Dasatinib in a Very Elderly CML Patient Expressing a Rare E13a3 Bcr-Abl1 Fusion Transcript: A Case Report.
BCR-ABL1 AND Dasatinib		31096222	1905-07-11	10.1159/000495335	Responses to Dasatinib as a Second- and Third-Line Tyrosine Kinase Inhibitor in Chronic Phase Chronic Myeloid Leukaemia Patients.
BCR-ABL1 AND Dasatinib		30916583	2019-04-05	10.1080/13543784.2019.1597052	Dasatinib as an investigational drug for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia in adults.
BCR-ABL1 AND Dasatinib		30711891	2019-3	10.1016/j.leukres.2018.12.013	A kinase profile-adapted drug combination elicits synergistic cooperative effects on leukemic cells carrying BCR-ABL1(T315I) in Ph+ CML.
BCR-ABL1 AND Dasatinib		30536062	2018-12	10.1007/s11596-018-1976-0	"Efficacy and Safety of Generic Dasatinib as a Second-line Treatment for Patients with Chronic Myeloid Leukemia: a Multicenter Retrospective Study in Hubei Province, China."
BCR-ABL1 AND Dasatinib		30465234	2018-11-22	10.1007/s40272-018-0319-8	Dasatinib: A Review in Pediatric Chronic Myeloid Leukemia.
BCR-ABL1 AND Dasatinib		30093398	2018-08-09	10.3324/haematol.2018.188987	"Incidence, outcomes, and risk factors of pleural effusion in patients receiving dasatinib therapy for Philadelphia chromosome-positive leukemia."
BCR-ABL1 AND Dasatinib		31723769	2018-6	10.1097/hs9.0000000000000041	Dasatinib-Loaded Erythrocytes Trigger Apoptosis in Untreated Chronic Myelogenous Leukemic Cells: A Cellular Reservoir Participating in Dasatinib Efficiency.
BCR-ABL1 AND Dasatinib		29723397	2018-05-03	10.1002/cncr.31357	Early results of lower dose dasatinib (50?mg daily) as frontline therapy for newly diagnosed chronic-phase chronic myeloid leukemia.
BCR-ABL1 AND Dasatinib		29719934	2018-05-29	10.1111/cas.13625	Pretreatment evaluation of fluorescence resonance energy transfer-based drug sensitivity test for patients with chronic myelogenous leukemia treated with dasatinib.
BCR-ABL1 AND Dasatinib		29222244	2017-12-08	10.1182/asheducation-2017.1.110	Cardiovascular care of patients with chronic myeloid leukemia (CML) on tyrosine kinase inhibitor (TKI) therapy.
BCR-ABL1 AND Dasatinib		29151104	2017-11-18	10.1159/000481945	Clinical Efficacy and Safety of First-Line Dasatinib Therapy and the Relevance of Velocity of BCR-ABL1 Transcript Decline for Achievement of Molecular Responses in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia: Report from the Juntendo Yamanashi
BCR-ABL1 AND Dasatinib		29033428	1905-07-10	10.2169/internalmedicine.9035-17	The Efficacy of Reduced-dose Dasatinib as a Subsequent Therapy in Patients with Chronic Myeloid Leukemia in the Chronic Phase: The LD-CML Study of the Kanto CML Study Group.
BCR-ABL1 AND Dasatinib		28895203	2017-10-16	10.1111/ejh.12969	Rapid reduction in BCR-ABL1 transcript predicts deep molecular response in dasatinib-treated chronic-phase chronic myeloid leukaemia patients.
BCR-ABL1 AND Dasatinib		28888102	2017-10	10.1016/j.leukres.2017.08.014	A new mechanism of resistance to ABL1 tyrosine kinase inhibitors in a BCR-ABL1-positive cell line.
BCR-ABL1 AND Dasatinib	BCR-ABL1 AND Ruxolitinib	28749919	2017-11-09	10.1182/blood-2017-06-743252	Philadelphia chromosome-like acute lymphoblastic leukemia: progress in a new cancer subtype.
BCR-ABL1 AND Dasatinib		28550414	2017-05-26	10.1007/s10147-017-1141-y	Dasatinib rapidly induces deep molecular response in chronic-phase chronic myeloid leukemia patients who achieved major molecular response with detectable levels of BCR-ABL1 transcripts by imatinib therapy.
BCR-ABL1 AND Dasatinib		28341918	2017-03-24	10.1007/s12185-017-2208-2	Dasatinib versus imatinib in Japanese patients with newly diagnosed chronic phase chronic myeloid leukemia: a subanalysis of the DASISION 5-year final report.
BCR-ABL1 AND Dasatinib		28283735	2017-03-10	10.1007/s00280-017-3264-2	In vitro and in vivo evaluation of dasatinib and imatinib on physiological parameters of pulmonary arterial hypertension.
BCR-ABL1 AND Dasatinib		27784993	2016-10	10.2147/dddt.s85050	Dasatinib for the treatment of chronic myeloid leukemia: patient selection and special considerations.
BCR-ABL1 AND Dasatinib		27192969	2016-06-20	10.1002/ajh.24423	"Dasatinib in imatinib-resistant or -intolerant chronic-phase, chronic myeloid leukemia patients: 7-year follow-up of study CA180-034."
BCR-ABL1 AND Dasatinib		27121472	2016-08-11	10.1182/blood-2016-02-700153	Dasatinib and low-intensity chemotherapy in elderly patients with Philadelphia chromosome-positive ALL.
BCR-ABL1 AND Dasatinib		26686407	2015-12	10.1016/s2352-3026(15)00196-9	Discontinuation of dasatinib in patients with chronic myeloid leukaemia who have maintained deep molecular response for longer than 1 year (DADI trial): a multicentre phase 2 trial.
BCR-ABL1 AND Dasatinib		26360368	2015-10	10.1097/pas.0000000000000488	Dasatinib-related Follicular Hyperplasia: An Underrecognized Entity With Characteristic Morphology.
BCR-ABL1 AND Dasatinib		26149409	2015-07-07	10.1007/s00428-015-1802-z	BCR-ABL1 e6a2 transcript in chronic myeloid leukemia: biological features and molecular monitoring by droplet digital PCR.
BCR-ABL1 AND Dasatinib		25083322	2014-5	10.4161/onci.28925	Dasatinib promotes Th1-type responses in granzyme B expressing T-cells.
BCR-ABL1 AND Dasatinib		24884315	2014-07-23	10.3109/10428194.2014.918969	Outcomes of chronic-phase chronic myeloid leukemia beyond first-line therapy.
BCR-ABL1 AND Dasatinib		24752059	2016-05-10	10.1200/jco.2013.51.1188	Molecular Response of e19a2 BCR-ABL1 Chronic Myeloid Leukemia With Double Philadelphia Chromosome to Dasatinib.
BCR-ABL1 AND Dasatinib		24553398	2014-6	10.1097/maj.0000000000000186	Second-generation tyrosine kinase inhibitors combined with stem cell transplantation in patients with imatinib-refractory chronic myeloid leukemia.
BCR-ABL1 AND Dasatinib		24210599	2014-2	10.1016/j.critrevonc.2013.10.005	"Dasatinib, large granular lymphocytosis, and pleural effusion: useful or adverse effect?"
BCR-ABL1 AND Dasatinib		23788844	2013-6	10.2147/cpaa.s42796	Differential effects of dosing regimen on the safety and efficacy of dasatinib: retrospective exposure-response analysis of a Phase III study.
BCR-ABL1 AND Dasatinib		22992064	2009-02-04	10.1002/cncr.24155	Dasatinib for the treatment of Philadelphia chromosome-positive leukemias.
BCR-ABL1 AND Dasatinib		22645182	2012-07-12	10.1182/blood-2012-01-407486	Predictive value of early molecular response in patients with chronic myeloid leukemia treated with first-line dasatinib.
BCR-ABL1 AND Dasatinib		22035739	2011-6	10.1016/j.clml.2011.03.032	Dasatinib combined with interferon-alfa induces a complete cytogenetic response and major molecular response in a patient with chronic myelogenous leukemia harboring the T315I BCR-ABL1 mutation.
BCR-ABL1 AND Dasatinib		21828123	2011-08-09	10.3324/haematol.2011.048165	"Durable complete molecular remission of chronic myeloid leukemia following dasatinib cessation, despite adverse disease features."
BCR-ABL1 AND Dasatinib		18978822	2008-11-03	10.1038/bmt.2008.354	Dasatinib-induced restoration of donor chimerism in BCR-ABL1-positive ALL after failure of imatinib therapy and allo-SCT.
BCR-ABL1 AND Nilotinib		37686630	2023-08-31	10.3390/cancers15174354	Hematological Adverse Events with Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia: A Systematic Review with Meta-Analysis.
BCR-ABL1 AND Nilotinib		37452432	2023-07-14	10.1002/advs.202302002	Chloroquine Intervenes Nephrotoxicity of Nilotinib through Deubiquitinase USP13-Mediated Stabilization of Bcl-XL.
BCR-ABL1 AND Nilotinib		35039265	2008-10	10.1016/j.leukres.2008.03.011	Clinical and laboratory relevance of JAK2 V617F and BCR-ABL co-existence in Philadelphia positive CML patients.
BCR-ABL1 AND Nilotinib	BCR-ABL1 AND Ponatinib	35018241	2019-07-04	10.1186/s12885-019-5871-2	PI3-kinase inhibition as a strategy to suppress the leukemic stem cell niche in Ph+ chronic myeloid leukemia.
BCR-ABL1 AND Nilotinib		34984204	2021-11-24	10.1055/s-0041-1733301	A Retrospective Cohort Study of Upfront Nilotinib in Chronic Myeloid Leukemia: A Single-Center Experience.
BCR-ABL1 AND Nilotinib		34884309	2021-11-29	10.3390/jcm10235606	Combined Inhibition of Bcl2 and Bcr-Abl1 Exercises Anti-Leukemia Activity but Does Not Eradicate the Primitive Leukemic Cells.
BCR-ABL1 AND Nilotinib	BCR-ABL1 AND Midostaurin	34238254	2021-07-08	10.1186/s12885-021-08479-z	Inference of kinase-signaling networks in human myeloid cell line models by Phosphoproteomics using kinase activity enrichment analysis (KAEA).
BCR-ABL1 AND Nilotinib		32688056	2021-10-11	10.1201/9781003120445-29	Early Prediction of Subsequent Molecular Response to Nilotinib in Patients with Chronic Myeloid Leukemia: Comparison of the Quantification of BCR-ABL1 Ratios Using ABL1 or GUSB Control Genes.
BCR-ABL1 AND Nilotinib		32354950	1905-07-12	10.21873/invivo.11933	Optimal Response in a Patient With CML Expressing BCR-ABL1 E6A2 Fusion Transcript With Nilotinib Therapy: A Case Report.
BCR-ABL1 AND Nilotinib		31999850	2020-01-30	10.1002/cncr.32623	Long-term results of a phase 2 trial of nilotinib 400�mg twice daily in newly diagnosed patients with chronic-phase chronic myeloid leukemia.
BCR-ABL1 AND Nilotinib		31409168	2019-08-13	10.1080/10428194.2019.1644332	Treatment patterns and deep molecular response in chronic phase - chronic myeloid leukemia patients treated with second-line nilotinib or dasatinib: a multi-country retrospective chart review study.
BCR-ABL1 AND Nilotinib		31318870	2019-07-18	10.1371/journal.pone.0218444	"Nilotinib interferes with cell cycle, ABC transporters and JAK-STAT signaling pathway in CD34+/lin- cells of patients with chronic phase chronic myeloid leukemia after 12 months of treatment."
BCR-ABL1 AND Nilotinib		31262918	2019-7	10.21873/anticanres.13540	Efficacy of Nilotinib in a CML Patient Expressing the Three-way Complex Variant Translocation t(2;9;22).
BCR-ABL1 AND Nilotinib	BCR-ABL1 AND Asciminib	31250767	2019-12-11	10.2174/1871520619666190620120144	The Perplexity of Synergistic Duality: Inter-molecular Mechanisms of Communication in BCR-ABL1.
BCR-ABL1 AND Nilotinib	BCR-ABL1 AND Asciminib	30877503	2019-03-15	10.1007/s10930-019-09820-z	A Synergistic Combination Against Chronic Myeloid Leukemia: An Intra-molecular Mechanism of Communication in BCR-ABL1 Resistance.
BCR-ABL1 AND Nilotinib		30121665	1905-07-10	10.1159/000490121	Successful Use of Nilotinib in the Therapy of a Patient with a Chemoresistant Relapse of BCR-ABL1-Like Phenotype Acute Lymphoblastic Leukemia.
BCR-ABL1 AND Nilotinib		29976734	2018-07-05	10.3324/haematol.2018.194894	Treatment-free remission after two-year consolidation therapy with nilotinib in patients with chronic myeloid leukemia: STAT2 trial in Japan.
BCR-ABL1 AND Nilotinib		29713954	2018-04-30	10.1007/s12185-018-2459-6	Switching to nilotinib is associated with deeper molecular responses in chronic myeloid leukemia chronic phase with major molecular responses to imatinib: STAT1 trial in Japan.
BCR-ABL1 AND Nilotinib		29531660	2018-3	10.1177/2040620718756603	Safety and efficacy of nilotinib in routine clinical practice in patients with chronic myeloid leukemia in chronic or accelerated phase with resistance or intolerance to imatinib: results from the NOVEL study.
BCR-ABL1 AND Nilotinib		29486663	2016-08-18	10.1080/14656566.2016.1219338	Outcomes with frontline nilotinib treatment in Turkish patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase.
BCR-ABL1 AND Nilotinib		29459949	2018-02-20	10.7326/m17-1094	"Treatment-Free Remission After Second-Line Nilotinib Treatment in Patients With Chronic Myeloid Leukemia in Chronic Phase: Results From a Single-Group, Phase 2, Open-Label Study."
BCR-ABL1 AND Nilotinib		29076005	2017-10-26	10.1007/s12185-017-2353-7	Nilotinib vs. imatinib in Japanese patients with newly diagnosed chronic myeloid leukemia in chronic phase: long-term follow-up of the Japanese subgroup of the randomized ENESTnd trial.
BCR-ABL1 AND Nilotinib		28699641	2017-07-12	10.1111/bjh.14829	Nilotinib dose-optimization in newly diagnosed chronic myeloid leukaemia in chronic phase: final results from ENESTxtnd.
BCR-ABL1 AND Nilotinib		28364360	2017-03-31	10.1007/s00432-017-2402-x	Impact of age on efficacy and toxicity of nilotinib in patients with chronic myeloid leukemia in chronic phase: ENEST1st subanalysis.
BCR-ABL1 AND Nilotinib		28224300	2017-02-21	10.1007/s00432-017-2359-9	Nilotinib first-line therapy in patients with Philadelphia chromosome-negative/BCR-ABL-positive chronic myeloid leukemia in chronic phase: ENEST1st sub-analysis.
BCR-ABL1 AND Nilotinib		28042454	2016-11-25	10.1177/2040620716678118	Exploratory study on the impact of switching to nilotinib in 18 patients with chronic myeloid leukemia in chronic phase with suboptimal response to imatinib.
BCR-ABL1 AND Nilotinib		27864817	2016-11-19	10.1186/s40792-016-0266-y	Surgical resection of recurrent gastrointestinal stromal tumor after interruption of long-term nilotinib therapy.
BCR-ABL1 AND Nilotinib		27771544	2016-12	10.1016/j.leukres.2016.09.009	Switching to nilotinib in patients with chronic myeloid leukemia in chronic phase with molecular suboptimal response to frontline imatinib: SENSOR final results and BIM polymorphism substudy.
BCR-ABL1 AND Nilotinib		27501474	2016-08-18	10.1080/14656566.2016.1219338	Outcomes with frontline nilotinib treatment in Turkish patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase.
BCR-ABL1 AND Nilotinib		27006491	2016-08-14	10.1158/1078-0432.ccr-15-2791	Leukemic Stem Cell Quantification in Newly Diagnosed Patients With Chronic Myeloid Leukemia Predicts Response to Nilotinib Therapy.
BCR-ABL1 AND Nilotinib		26437782	2015-10-06	10.1038/leu.2015.270	Frontline nilotinib in patients with chronic myeloid leukemia in chronic phase: results from the European ENEST1st study.
BCR-ABL1 AND Nilotinib		26065651	2015-08-06	10.1182/blood-2015-03-636548	Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia.
BCR-ABL1 AND Nilotinib		25882987	2015-5	10.1016/s1470-2045(15)70105-1	Nilotinib versus imatinib as first-line therapy for patients with unresectable or metastatic gastrointestinal stromal tumours (ENESTg1): a randomised phase 3 trial.
BCR-ABL1 AND Nilotinib		25766724	2015-04-30	10.1182/blood-2014-09-601674	Phase 3 study of nilotinib vs imatinib in Chinese patients with newly diagnosed chronic myeloid leukemia in chronic phase: ENESTchina.
BCR-ABL1 AND Nilotinib		24948656	2014-07-31	10.1182/blood-2013-12-544015	Deep molecular responses achieved in patients with CML-CP who are switched to nilotinib after long-term imatinib.
BCR-ABL1 AND Nilotinib		24650752	2014-03-20	10.1186/2050-7771-2-6	Multicenter phase II clinical trial of nilotinib for patients with imatinib-resistant or -intolerant chronic myeloid leukemia from the East Japan CML study group evaluation of molecular response and the efficacy and safety of nilotinib.
BCR-ABL1 AND Nilotinib		24373969	2014-1	10.1016/j.celrep.2013.12.002	FuseFISH: robust detection of transcribed gene fusions in single cells.
BCR-ABL1 AND Nilotinib		24333114	2014-3	10.1016/j.leukres.2013.11.016	Nilotinib 300 mg BID as frontline treatment of CML: prospective analysis of the Xpert BCR-ABL monitor system and significance of 3-month molecular response.
BCR-ABL1 AND Nilotinib		22763385	2012-07-05	10.1038/leu.2012.181	Nilotinib in imatinib-resistant or imatinib-intolerant patients with chronic myeloid leukemia in chronic phase: 48-month follow-up results of a phase II study.
BCR-ABL1 AND Nilotinib		21345139	2011-2	10.2217/fon.10.174	Nilotinib: evaluation and analysis of its role in chronic myeloid leukemia.
BCR-ABL1 AND Nilotinib		21121868	2010-12-02	10.1517/14740338.2011.532486	The expanding role of nilotinib in chronic myeloid leukemia.
BCR-ABL1 AND Nilotinib		20817538	2010-10	10.1016/j.bmc.2010.08.026	Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.
BCR-ABL1 AND Crizotinib		34110462	2021-06-10	10.1007/s00277-020-04357-z	Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1(T315I) and BCR-ABL1(T315I-E255K).
BCR-ABL1 AND Ruxolitinib		37434824	2022-07-01	10.21203/rs.3.rs-1776640/v1	Extremely rare chronic neutrophilic leukemia characterized by unrelieved abdominal distention and swollen painful limbs: new clinical insight.
BCR-ABL1 AND Ruxolitinib		34903489	2022-5	10.1016/j.clml.2021.11.007	State-of-the-Art Review on Myelofibrosis Therapies.
BCR-ABL1 AND Ruxolitinib		33860589	2021-04-16	10.1111/petr.14024	Clinical Efficacy of Ruxolitinib Monotherapy and Haploidentical Hematopoeitic Stem Cell Transplantation in a Child with Philadelphia Chromosome-like Relapsed/Refractory acute lymphoblastic leukemia.
BCR-ABL1 AND Ruxolitinib		32201152	2021-9	10.1016/j.hemonc.2020.02.003	Reactivation of tuberculosis following ruxolitinib therapy for primary myelofibrosis: Case series and literature review.
BCR-ABL1 AND Ruxolitinib	BCR-ABL1 AND Fedratinib	32198525	2019-9	10.1016/j.clml.2019.07.400	Management of myelofibrosis after ruxolitinib failure.
BCR-ABL1 AND Ruxolitinib		29399328	2018-01-17	10.12688/f1000research.13167.1	JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders.
BCR-ABL1 AND Ruxolitinib		28554272	2017-05-30	10.1080/10428194.2017.1324155	"Angiogenesis in JAK2 V617F positive myeloproliferative neoplasms and ruxolitinib decrease VEGF, HIF-1 enesis in JAK2 V617F positive cells."
BCR-ABL1 AND Ruxolitinib		27017614	2016-03-26	10.1007/s00280-016-3012-z	Overcoming treatment challenges in myelofibrosis and polycythemia vera: the role of ruxolitinib.
BCR-ABL1 AND Ruxolitinib		25520049	2014-12	10.3109/10428194.2014.985159	Is there a role for JAK inhibitors in BCR-ABL1-negative myeloproliferative neoplasms other than myelofibrosis?
BCR-ABL1 AND Ruxolitinib		23610611	2012-10-01	10.1177/2040620712461047	Comprehensive review of JAK inhibitors in myeloproliferative neoplasms.
BCR-ABL1 AND Ruxolitinib		23391678	2013-1	10.3810/pgm.2013.01.2628	Ruxolitinib: an oral Janus kinase 1 and Janus kinase 2 inhibitor in the management of myelofibrosis.
BCR-ABL1 AND Ruxolitinib		22875628	2012-08-08	10.3324/haematol.2012.067959	Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements.
BCR-ABL1 AND Ruxolitinib		22875628	2012-08-08	10.3324/haematol.2012.067959	Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements.
BCR-ABL1 AND Ruxolitinib		22830345	2012-09-01	10.2174/092986712803251511	Biology and clinical management of myeloproliferative neoplasms and development of the JAK inhibitor ruxolitinib.
BCR-ABL1 AND Ruxolitinib		22474318	2012-05-31	10.1158/1078-0432.ccr-11-3145	Ruxolitinib: the first FDA approved therapy for the treatment of myelofibrosis.
BCR-ABL1 AND Axitinib	BCR-ABL1 AND Ponatinib	33419251	2020-12-20	10.3390/ijms21249724	Axitinib in Ponatinib-Resistant B-Cell Acute Lymphoblastic Leukemia Harboring a T315L Mutation.
BCR-ABL1 AND Axitinib		32879093	2010-9	10.1016/j.leukres.2010.03.036	Combination of axitinib with dasatinib improves the outcome of a chronic myeloid leukemia patient with BCR-ABL1 T315I mutation.
BCR-ABL1 AND Axitinib	BCR-ABL1 AND Asciminib	32380976	2020-05-07	10.1186/s12885-020-06782-9	The effects of combination treatments on drug resistance in chronic myeloid leukaemia: an evaluation of the tyrosine kinase inhibitors axitinib and asciminib.
BCR-ABL1 AND Axitinib		25686603	2015-02-09	10.1038/nature14119	Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation.
BCR-ABL1 AND Bosutinib		32572189	2020-06-22	10.1038/s41375-020-0915-9	Bosutinib for pretreated patients with chronic phase chronic myeloid leukemia: primary results of the phase 4 BYOND study.
BCR-ABL1 AND Bosutinib		30587215	2018-12	10.1186/s13045-018-0685-2	Management of adverse events associated with bosutinib treatment of chronic-phase chronic myeloid leukemia: expert panel review.
BCR-ABL1 AND Bosutinib		26537529	2015-11-04	10.1111/bjh.13801	Factors influencing long-term efficacy and tolerability of bosutinib in chronic phase chronic myeloid leukaemia resistant or intolerant to imatinib.
BCR-ABL1 AND Bosutinib		31388478	2014-2	10.2217/fon.13.268	Bosutinib for the Treatment of Philadelphia Chromosome-Positive Leukemias.
BCR-ABL1 AND Bosutinib		25196702	2011-11-18	10.1182/blood.v118.21.455.455	Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukaemia: results from the 24-month follow-up of the BELA trial.
BCR-ABL1 AND Bosutinib		25045255	2014-7	10.2147/ppa.s53160	Clinical advances in the management of chronic myelogenous leukemia: focus on bosutinib and patient considerations.
BCR-ABL1 AND Bosutinib		22462037	1905-07-04	10.1358/dot.2012.48.3.1750274	Bosutinib for the treatment of chronic myeloid leukemia in chronic phase.
BCR-ABL1 AND Ponatinib		36448578	2022-11-30	10.1080/16078454.2022.2150386	De novo lymphoid blastic phase chronic myeloid leukemia: report and contemporary discussion.
BCR-ABL1 AND Ponatinib		36402146	2023-1	10.1016/s2352-3026(22)00319-2	"Ponatinib and blinatumomab for Philadelphia chromosome-positive acute lymphoblastic leukaemia: a US, single-centre, single-arm, phase 2 trial."
BCR-ABL1 AND Ponatinib	BCR-ABL1 AND Asciminib	36233014	2022-10-03	10.3390/ijms231911711	Investigating Potential Cardiovascular Toxicity of Two Anti-Leukemia Drugs of Asciminib and Ponatinib in Zebrafish Embryos.
BCR-ABL1 AND Ponatinib		36174582	2022-11	10.1016/s2352-3026(22)00246-0	"The influence of drug prices, new availability of inexpensive generic imatinib, new approvals, and post-marketing research on the treatment of chronic myeloid leukaemia in the USA."
BCR-ABL1 AND Ponatinib		35725593	2012-11-29	10.1056/nejme1210796	French Chronic Myeloid Leukemia Intergroup 2022 recommendations for managing the risk of cardiovascular events on ponatinib in chronic myeloid leukemia
BCR-ABL1 AND Ponatinib		35544670	2022-05-04	10.1080/17474086.2022.2077187	An evaluation of ponatinib as a therapy in adult patients with resistant/intolerant chronic-phase chronic myeloid leukemia.
BCR-ABL1 AND Ponatinib		35412404	2022-04-12	10.1080/14656566.2022.2064742	Ponatinib for the treatment of adult patients with resistant or intolerant Chronic-Phase Chronic Myeloid Leukemia.
BCR-ABL1 AND Ponatinib		35008283	2021-12-27	10.3390/cancers14010119	Neutrophil Extracellular Traps Are Increased in Chronic Myeloid Leukemia and Are Differentially Affected by Tyrosine Kinase Inhibitors.
BCR-ABL1 AND Ponatinib		34987886	2021-11-27	10.7759/cureus.19949	Bowel Perforation Secondary to Ponatinib Treatment in a Chronic Myelogenous Leukemia Patient: A Case Report.
BCR-ABL1 AND Ponatinib		34906334	2022-2	10.1016/s2352-3026(21)00370-7	"Ponatinib with fludarabine, cytarabine, idarubicin, and granulocyte colony-stimulating factor chemotherapy for patients with blast-phase chronic myeloid leukaemia (MATCHPOINT): a single-arm, multicentre, phase 1/2 trial."
BCR-ABL1 AND Ponatinib		34842047	2021-11-28	10.1080/07391102.2021.2004924	STAT5 inhibitor Pimozide as a probable therapeutic option in overcoming Ponatinib resistance in K562 leukemic cells.
BCR-ABL1 AND Ponatinib		34699069	2021-12-16	10.1002/jcph.1990	Population Pharmacokinetics of Ponatinib in Healthy Adult Volunteers and Patients With Hematologic Malignancies and Model-Informed Dose Selection for Pediatric Development.
BCR-ABL1 AND Ponatinib	BCR-ABL1 AND Asciminib	34659899	2014-11-01	10.1158/2159-8290.cd-rw2014-186	Asciminib and ponatinib exert synergistic anti-neoplastic effects on CML cells expressing BCR-ABL1 (T315I)-compound mutations.
BCR-ABL1 AND Ponatinib		34407543	2021-11-25	10.1182/blood.2021012082	"Ponatinib dose-ranging study in chronic-phase chronic myeloid leukemia: a randomized, open-label phase 2 clinical trial."
BCR-ABL1 AND Ponatinib		34130278	1905-07-13	10.1159/000516003	Clinical Efficacy of Ponatinib in Philadelphia-Positive T-Cell Acute Lymphoblastic Leukemia with Extramedullary Involvement.
BCR-ABL1 AND Ponatinib		33907977	2021-04-27	10.1007/s12185-021-03156-0	Efficacy and safety of ponatinib for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: a case series from a single institute.
BCR-ABL1 AND Ponatinib		33796468	2021-03-16	10.3389/fonc.2021.642005	Dosing Strategies for Improving the Risk-Benefit Profile of Ponatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase.
BCR-ABL1 AND Ponatinib		33774681	2021-03-28	10.1007/s00277-021-04504-0	The role of ponatinib in adult BCR-ABL1 positive acute lymphoblastic leukemia after allogeneic transplantation: a real-life retrospective multicenter study.
BCR-ABL1 AND Ponatinib		32470534	2020-10	10.1016/j.ijcard.2020.05.077	Cardiotoxicity of the BCR-ABL1 tyrosine kinase inhibitors: Emphasis on ponatinib.
BCR-ABL1 AND Ponatinib		32242465	2020-4	10.1177/0300060520903660	A patient with maculopapular rash and lichenoid skin damage caused by ponatinib.
BCR-ABL1 AND Ponatinib		32145037	2020-03-15	10.1111/ejh.13408	The multi-tyrosine kinase inhibitor ponatinib for chronic myeloid leukemia: Real-world data.
BCR-ABL1 AND Ponatinib	BCR-ABL1 AND Palbociclib	31761618	2019-12	10.1016/j.ebiom.2019.11.004	CDK4/CDK6 inhibition as a novel strategy to suppress the growth and survival of BCR-ABL1(T315I)+ clones in TKI-resistant CML.
BCR-ABL1 AND Ponatinib	BCR-ABL1 AND Asciminib	31543464	2019-10	10.1016/j.ccell.2019.08.004	Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 Mutants.
BCR-ABL1 AND Ponatinib		30854182	2019-1	10.1177/2040620719826444	Insights into the optimal use of ponatinib in patients with chronic phase chronic myeloid leukaemia.
BCR-ABL1 AND Ponatinib		30692122	2019-04-04	10.1182/blood-2018-10-881557	Thrombotic microangiopathy as a cause of cardiovascular toxicity from the BCR-ABL1 tyrosine kinase inhibitor ponatinib.
BCR-ABL1 AND Ponatinib		30526517	2018-12	10.1186/s12885-018-5100-4	Ponatinib induces a sustained deep molecular response in a chronic myeloid leukaemia patient with an early relapse with a T315I mutation following allogeneic hematopoietic stem cell transplantation: a case report.
BCR-ABL1 AND Ponatinib		30501869	2018-12	10.1016/s2352-3026(18)30176-5	"Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: long-term follow-up of a single-centre, phase 2 study."
BCR-ABL1 AND Ponatinib		30410673	2018-10-05	10.18632/oncotarget.26187	Modelling ponatinib resistance in tyrosine kinase inhibitor-na�ve and dasatinib resistant BCR-ABL1+ cell lines.
BCR-ABL1 AND Ponatinib		30251548	2019-1	10.2217/fon-2018-0371	Ponatinib in the treatment of chronic myeloid leukemia and philadelphia chromosome positive acute lymphoblastic leukemia.
BCR-ABL1 AND Ponatinib		29845876	2018-05-30	10.1080/14740338.2018.1480719	Intolerance to tyrosine kinase inhibitors in chronic myeloid leukemia: the possible role of ponatinib.
BCR-ABL1 AND Ponatinib		29608815	2018-05-22	10.1002/cmdc.201700829	Alkynylnicotinamide-Based Compounds as ABL1 Inhibitors with Potent Activities against Drug-Resistant CML Harboring ABL1(T315I) Mutant Kinase.
BCR-ABL1 AND Ponatinib		29567798	2018-07-26	10.1182/blood-2016-09-739086	Ponatinib efficacy and safety in Philadelphia chromosome-positive leukemia: final 5-year results of the phase 2 PACE trial.
BCR-ABL1 AND Ponatinib		28969556	2018-10-17	10.2174/1568009617666171002142659	Ponatinib: A Review of Efficacy and Safety.
BCR-ABL1 AND Ponatinib		28880088	2017-09-19	10.1021/acs.molpharmaceut.7b00257	"Brain Accumulation of Ponatinib and Its Active Metabolite, N-Desmethyl Ponatinib, Is Limited by P-Glycoprotein (P-GP/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2)."
BCR-ABL1 AND Ponatinib		28779753	2017-08-05	10.1186/s12885-017-3511-2	The clonal evolution of two distinct T315I-positive BCR-ABL1 subclones in a Philadelphia-positive acute lymphoblastic leukemia failing multiple lines of therapy: a case report.
BCR-ABL1 AND Ponatinib		27957861	2016-12-13	10.1021/acs.molpharmaceut.6b00872	Codelivery of Ponatinib and SAR302503 by Active Bone-Targeted Polymeric Micelles for the Treatment of Therapy-Resistant Chronic Myeloid Leukemia.
BCR-ABL1 AND Ponatinib		27901368	2016-12-09	10.1080/14656566.2016.1267141	Second line small molecule therapy options for treating chronic myeloid leukemia.
BCR-ABL1 AND Ponatinib		27505637	2014-12-06	10.1182/blood.v124.21.4546.4546	Impact of dose intensity of ponatinib on selected adverse events: Multivariate analyses from a pooled population of clinical trial patients.
BCR-ABL1 AND Ponatinib		27179188	2016-6	10.1016/j.jchromb.2016.04.049	Liquid chromatography-tandem mass spectrometric assay for ponatinib and N-desmethyl ponatinib in mouse plasma.
BCR-ABL1 AND Ponatinib		26603839	2016-02-11	10.1182/blood-2015-08-660977	Compound mutations in BCR-ABL1 are not major drivers of primary or secondary resistance to ponatinib in CP-CML patients.
BCR-ABL1 AND Ponatinib		26432046	2015-11	10.1016/s1470-2045(15)00207-7	"Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: a single-centre, phase 2 study."
BCR-ABL1 AND Ponatinib		25361807	2014-10-31	10.6004/jnccn.2014.0160	Where exactly does ponatinib fit in chronic myelogenous leukemia?
BCR-ABL1 AND Ponatinib		25132497	2014-9	10.1016/j.ccr.2014.07.006	BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia.
BCR-ABL1 AND Trametinib		35949766	2022-07-06	10.7759/cureus.26619	Trametinib: Could It Be a Promising Drug to Treat Atypical Chronic Myeloid Leukemia?
BCR-ABL1 AND Gilteritinib		36843408	2023-02-24	10.3343/alm.2023.43.4.386	Emergence of BCR-ABL1 (p190) in Acute Myeloid Leukemia Post-Gilteritinib Therapy.
BCR-ABL1 AND Gilteritinib		31088841	2019-08-01	10.1158/2159-8290.cd-18-1453	Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia.
BCR-ABL1 AND Asciminib		37189659	2023-03-28	10.3390/biomedicines11041041	Artificial Intelligence Assisted Pharmacophore Design for Philadelphia Chromosome-Positive Leukemia with Gamma-Tocotrienol: A Toxicity Comparison Approach with Asciminib.
BCR-ABL1 AND Asciminib		37141403	2023-05-04	10.1093/oncolo/oyad119	The EMA Assessment of Asciminib for the Treatment of Adult Patients With Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase Who Were Previously Treated With at Least Two Tyrosine Kinase Inhibitors.
BCR-ABL1 AND Asciminib		37102603	2023-04-27	10.3324/haematol.2022.282361	Asciminib in chronic myeloid leukemia: a STAMP for expedited delivery?
BCR-ABL1 AND Asciminib		36197958	2022-10-05	10.1093/ajhp/zxac286	Asciminib (Scemblix): A third-line treatment option for chronic myeloid leukemia in chronic phase with or without T315I mutation.
BCR-ABL1 AND Asciminib		36168187	2022-09-27	10.1002/cam4.5212	Asciminib vs bosutinib in CML patients pretreated with ?2 tyrosine kinase inhibitors: Results from the Japanese subgroup analysis of ASCEMBL study.
BCR-ABL1 AND Asciminib		35764773	2022-06-28	10.1007/s40262-022-01148-9	Population Pharmacokinetics of Asciminib in Tyrosine Kinase Inhibitor-Treated Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic and Acute Phases.
BCR-ABL1 AND Asciminib		35729850	2022-06-21	10.1111/bjh.18323	Asciminib for chronic myeloid leukaemia: Next questions.
BCR-ABL1 AND Asciminib		35293131	2022-03-15	10.1111/cts.13252	"Pharmacokinetic drug interactions of asciminib with the sensitive cytochrome P450 probe substrates midazolam, warfarin, and repaglinide in healthy participants."
BCR-ABL1 AND Asciminib		35065232	2022-3	10.1016/j.bmcl.2022.128577	"A kinase inhibitor which specifically targets the ABL myristate pocket (STAMP), but unlike asciminib crosses the blood-brain barrier."
BCR-ABL1 AND Asciminib		35041175	2022-01-18	10.1007/s40265-021-01662-3	Asciminib: First Approval.
BCR-ABL1 AND Asciminib		35021069	2022-3	10.1016/j.critrevonc.2022.103580	"Development of asciminib, a novel allosteric inhibitor of BCR-ABL1."
BCR-ABL1 AND Asciminib		34407542	2021-11-25	10.1182/blood.2020009984	"A phase 3, open-label, randomized study of asciminib, a STAMP inhibitor, vs bosutinib in CML after 2 or more prior TKIs."
BCR-ABL1 AND Asciminib		34115385	2021-07-16	10.1002/jcph.1926	Pharmacokinetics of Asciminib in Individuals With Hepatic or Renal Impairment.
BCR-ABL1 AND Asciminib		33096322	2020-11	10.1016/j.leukres.2020.106458	"The specificity of asciminib, a potential treatment for chronic myeloid leukemia, as a myristate-pocket binding ABL inhibitor and analysis of its interactions with mutant forms of BCR-ABL1 kinase."
BCR-ABL1 AND Asciminib		31826340	2019-12-12	10.1056/nejmoa1902328	Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure.
BCR-ABL1 AND Asciminib		31006307	2019-05-06	10.1080/00498254.2019.1594449	"Disposition of asciminib, a potent BCR-ABL1 tyrosine kinase inhibitor, in healthy male subjects."
BCR-ABL1 AND Asciminib		30137981	None	10.1021/acs.jmedchem.8b01040.s001	"Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1."
BCR-ABL1 AND Asciminib		29568367	2018-02-03	10.18632/oncotarget.24393	The new allosteric inhibitor asciminib is susceptible to resistance mediated by ABCB1 and ABCG2 overexpression in vitro.

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Related Diseases to BCR_ABL1

Diseases that have this fusion gene. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene	Tgene	Disease	Source	PMID
BCR	ABL1	Chronic Myelogenous Leukemi	PubMed	32000382
BCR	ABL1	Chronic Myeloid Leukemia	MyCancerGenome
BCR	ABL1	Breast Invasive Ductal Carcinoma	MyCancerGenome
BCR	ABL1	Unknown	MyCancerGenome
BCR	ABL1	B-Cell Lymphoblastic Leukemia/Lymphoma	MyCancerGenome
BCR	ABL1	Acute Myeloid Leukemia	MyCancerGenome

Related diseases from the literature mentioned this fusion gene and drug. (PubMed, 04-01-2024)

MeSH ID	MeSH term
D054198	Precursor Cell Lymphoblastic Leukemia-Lymphoma
D006689	Hodgkin Disease
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015452	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
D015452	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
D007938	Leukemia
D002318	Cardiovascular Diseases, Disease Progression, Leukemia, Myeloid, Chronic-Phase
D018450	Cardiovascular Diseases, Disease Progression, Leukemia, Myeloid, Chronic-Phase
D015466	Cardiovascular Diseases, Disease Progression, Leukemia, Myeloid, Chronic-Phase
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D018450	Disease Progression, Disease-Free Survival, Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D018572	Disease Progression, Disease-Free Survival, Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015464	Disease Progression, Disease-Free Survival, Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase
D015466	Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D054198	Precursor Cell Lymphoblastic Leukemia-Lymphoma
D054198	Precursor Cell Lymphoblastic Leukemia-Lymphoma
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015466	Leukemia, Myeloid, Chronic-Phase
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015452	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
D054198	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
D054218	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
D018572	Disease-Free Survival, Leukemia, Myeloid, Chronic-Phase
D015466	Disease-Free Survival, Leukemia, Myeloid, Chronic-Phase
D054198	Precursor Cell Lymphoblastic Leukemia-Lymphoma
D009190	Myelodysplastic Syndromes
D054198	Precursor Cell Lymphoblastic Leukemia-Lymphoma
D018572	Disease-Free Survival, Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015464	Disease-Free Survival, Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015466	Leukemia, Myeloid, Chronic-Phase
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Precursor Cell Lymphoblastic Leukemia-Lymphoma
D054198	Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Precursor Cell Lymphoblastic Leukemia-Lymphoma
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Precursor Cell Lymphoblastic Leukemia-Lymphoma
D054198	Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Precursor Cell Lymphoblastic Leukemia-Lymphoma
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D018450	Disease Progression, Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015464	Disease Progression, Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D054198	Precursor Cell Lymphoblastic Leukemia-Lymphoma
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D004195	Disease Models, Animal
D054198	Precursor Cell Lymphoblastic Leukemia-Lymphoma
D006331	Heart Diseases
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015466	Leukemia, Myeloid, Chronic-Phase
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D054198	Precursor Cell Lymphoblastic Leukemia-Lymphoma
D015466	Leukemia, Myeloid, Chronic-Phase
D054198	Precursor Cell Lymphoblastic Leukemia-Lymphoma
D018572	Disease-Free Survival
D015466	Leukemia, Myeloid, Chronic-Phase
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D019468	Disease Management
D015466	Leukemia, Myeloid, Chronic-Phase
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D019468	Disease Management, Disease Susceptibility, Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D004198	Disease Management, Disease Susceptibility, Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015464	Disease Management, Disease Susceptibility, Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015470	Leukemia, Myeloid, Acute
D015464	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
D015466	Leukemia, Myeloid, Chronic-Phase

Diseases associated with fusion partners. (DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	BCR	C0005586	Bipolar Disorder	4	PSYGENET
Hgene	BCR	C0023473	Myeloid Leukemia, Chronic	3	CTD_human;ORPHANET
Tgene	ABL1	C0023473	Myeloid Leukemia, Chronic	3	CGI;CTD_human;ORPHANET
Tgene	ABL1	C0023452	Childhood Acute Lymphoblastic Leukemia	2	CTD_human
Tgene	ABL1	C0023453	L2 Acute Lymphoblastic Leukemia	2	CTD_human
Tgene	ABL1	C1961102	Precursor Cell Lymphoblastic Leukemia Lymphoma	2	CGI;CTD_human

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Clinical Trials of the Found Drugs/Small Molecules

Statistics of the Clinical Trials of the Found Kinase Inibitors from clinicaltrials.gov (06-17-2024)

Clinical Trials from clinicaltrials.gov (06-17-2024)

Fusion Gene	Kinase Inhibitor	NCT ID	Study Status	Phases	Disease	# Enrolment	Date
BCR-ABL1	Asciminib	NCT04216563	Active, not recruiting	Phase 2	Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia	40	December 31, 2025
BCR-ABL1	Asciminib	NCT03106779	Active, not recruiting	Phase 3	Chronic Myelogenous Leukemia	233	December 18, 2024
BCR-ABL1	Asciminib	NCT04948333	Active, not recruiting	Phase 3	Chronic Myelogenous Leukemia	199	July 31, 2026
BCR-ABL1	Asciminib	NCT03906292	Active, not recruiting	Phase 2	Chronic Myeloid Leukemia	125	December 2027
BCR-ABL1	Asciminib	NCT03578367	Active, not recruiting	Phase 2	CML	104	February 6, 2025
BCR-ABL1	Asciminib	NCT04971226	Active, not recruiting	Phase 3	Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive	404	January 18, 2028
BCR-ABL1	Bosutinib	NCT03106779	Active, not recruiting	Phase 3	Chronic Myelogenous Leukemia	233	December 18, 2024
BCR-ABL1	Bosutinib	NCT03654768	Active, not recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	84	July 1, 2028
BCR-ABL1	Bosutinib	NCT04971226	Active, not recruiting	Phase 3	Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive	404	January 18, 2028
BCR-ABL1	Dasatinib	NCT02689440	Active, not recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	155	December 31, 2040
BCR-ABL1	Dasatinib	NCT00070499	Active, not recruiting	Phase 2	Chronic Myeloid Leukemia, BCR-ABL1 Positive	406	February 22, 2025
BCR-ABL1	Dasatinib	NCT00254423	Active, not recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	156	November 30, 2024
BCR-ABL1	Dasatinib	NCT02494882	Active, not recruiting	Phase 1	Acute Lymphoblastic Leukemia	12	June 2025
BCR-ABL1	Dasatinib	NCT03654768	Active, not recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	84	July 1, 2028
BCR-ABL1	Imatinib	NCT00070499	Active, not recruiting	Phase 2	Chronic Myeloid Leukemia, BCR-ABL1 Positive	406	February 22, 2025
BCR-ABL1	Imatinib	NCT03654768	Active, not recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	84	July 1, 2028
BCR-ABL1	Imatinib	NCT03578367	Active, not recruiting	Phase 2	CML	104	February 6, 2025
BCR-ABL1	Nilotinib	NCT01784068	Active, not recruiting	Phase 2	Chronic Myelogenous Leukemia	215	February 20, 2025
BCR-ABL1	Nilotinib	NCT03654768	Active, not recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	84	July 1, 2028
BCR-ABL1	Nilotinib	NCT03578367	Active, not recruiting	Phase 2	CML	104	February 6, 2025
BCR-ABL1	Nilotinib	NCT03906292	Active, not recruiting	Phase 2	Chronic Myeloid Leukemia	125	December 2027
BCR-ABL1	Nilotinib	NCT02917720	Active, not recruiting	Phase 2	Chronic Myeloid Leukemia	75	September 2027
BCR-ABL1	Nilotinib	NCT04147533	Active, not recruiting	Phase 2	Chronic Myeloid Leukemia, Chronic Phase	150	June 2026
BCR-ABL1	Nilotinib	NCT04216563	Active, not recruiting	Phase 2	Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia	40	December 31, 2025
BCR-ABL1	Ponatinib	NCT02467270	Active, not recruiting	Phase 2	Myeloid Leukemia, Chronic, Chronic Phase	283	June 1, 2024
BCR-ABL1	Ponatinib	NCT03589326	Active, not recruiting	Phase 3	Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)	245	July 31, 2027
BCR-ABL1	Ponatinib	NCT03147612	Active, not recruiting	Phase 2	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	22	February 28, 2025
BCR-ABL1	Ponatinib	NCT04188405	Active, not recruiting	Phase 2	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	30	September 1, 2024
BCR-ABL1	Ponatinib	NCT03576547	Active, not recruiting	Phase 1	Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	11	August 31, 2024
BCR-ABL1	Ponatinib	NCT01424982	Active, not recruiting	Phase 2	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	88	October 31, 2025
BCR-ABL1	Ponatinib	NCT02629692	Active, not recruiting	Phase 1	Healthy (For Part A)	122	August 2026
BCR-ABL1	Ruxolitinib	NCT03654768	Active, not recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	84	July 1, 2028
BCR-ABL1	Ruxolitinib	NCT02494882	Active, not recruiting	Phase 1	Acute Lymphoblastic Leukemia	12	June 2025
BCR-ABL1	Ruxolitinib	NCT03117751	Active, not recruiting	Phase 2	Acute Lymphoblastic Leukemia	790	March 31, 2028
BCR-ABL1	Asciminib	NCT05421091	Completed		Chronic Myeloid Leukemia	550	February 29, 2024
BCR-ABL1	Bosutinib	NCT02810990	Completed	Phase 2	Chronic Myeloid Leukemia	65	June 22, 2022
BCR-ABL1	Bosutinib	NCT02311998	Completed	Phase 1	B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1	22	March 23, 2022
BCR-ABL1	Bosutinib	NCT02546375	Completed		Chronic Myeloid Leukaemia	87	January 16, 2017
BCR-ABL1	Bosutinib	NCT03045120	Completed		Chronic Phase Chronic Myeloid Leukemia	118	June 20, 2022
BCR-ABL1	Dasatinib	NCT00720109	Completed	Phase 2	Acute Lymphoblastic Leukemia	63	March 31, 2020
BCR-ABL1	Dasatinib	NCT01256398	Completed	Phase 2	Acute Lymphoblastic Leukemia	66	November 15, 2021
BCR-ABL1	Dasatinib	NCT04925141	Completed	Phase 4	Chronic Myelogenous Leukemia - Chronic Phase	62	December 6, 2019
BCR-ABL1	Dasatinib	NCT03625388	Completed	Phase 2	Chronic Myelogenous Leukemia	56	July 22, 2023
BCR-ABL1	Dasatinib	NCT01725204	Completed	Phase 2	Leukemia, Myeloid, Chronic-Phase	40	May 2016
BCR-ABL1	Imatinib	NCT02896829	Completed		Chronic Myeloid Leukemia	97	April 2019
BCR-ABL1	Imatinib	NCT00049192	Completed	Phase 2	Chronic Myelogenous Leukemia, BCR-ABL1 Positive	43
BCR-ABL1	Imatinib	NCT00030394	Completed	Phase 2	Childhood Chronic Myelogenous Leukemia	64
BCR-ABL1	Imatinib	NCT00093639	Completed	Phase 1	Leukemia		August 2006
BCR-ABL1	Imatinib	NCT00015834	Completed	Phase 1	Blastic Phase Chronic Myelogenous Leukemia	46
BCR-ABL1	Nilotinib	NCT03332511	Completed	Phase 4	Chronic Myeloid Leukemia, Chronic Phase	110	October 24, 2016
BCR-ABL1	Nilotinib	NCT00809211	Completed	Phase 2	Leukemia	40	February 2016
BCR-ABL1	Nilotinib	NCT00769327	Completed	Phase 2	Leukemia	129	October 10, 2014
BCR-ABL1	Nilotinib	NCT01274351	Completed	Phase 2	Chronic Myelogenous Leukemia	112	August 1, 2019
BCR-ABL1	Ruxolitinib	NCT02092324	Completed	Phase 2	Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative	51	January 24, 2020
BCR-ABL1	Ruxolitinib	NCT01164163	Completed	Phase 1	Chronic Myeloproliferative Disorders	49
BCR-ABL1	Sorafenib	NCT01445080	Completed	Phase 1	Blastic Phase	70	December 10, 2012
BCR-ABL1	Asciminib	NCT06409936	Not yet recruiting	Phase 2	CML, Chronic Phase	160	September 2031
BCR-ABL1	Imatinib	NCT05367765	Not yet recruiting	Phase 4	CML, Chronic Phase	2400	April 30, 2028
BCR-ABL1	Nilotinib	NCT06409936	Not yet recruiting	Phase 2	CML, Chronic Phase	160	September 2031
BCR-ABL1	Ponatinib	NCT04688983	Not yet recruiting	Phase 2	Acute Lymphoblastic Leukemia, Adult	180	January 2026
BCR-ABL1	Asciminib	NCT05384587	Recruiting	Phase 2	Chronic Myelogenous Leukemia - Chronic Phase	182	February 26, 2027
BCR-ABL1	Asciminib	NCT05413915	Recruiting	Phase 3	Chronic Myeloid Leukemia	164	December 2025
BCR-ABL1	Asciminib	NCT05943522	Recruiting		Chronic Myeloid Leukemia	100	July 31, 2025
BCR-ABL1	Asciminib	NCT05143840	Recruiting	Phase 2	Chronic Myeloid Leukemia, Chronic Phase	8	February 2027
BCR-ABL1	Asciminib	NCT02643888	Recruiting		Leukemia	30	May 2023
BCR-ABL1	Asciminib	NCT06092879	Recruiting		Chronic Myeloid Leukemia	168	December 15, 2026
BCR-ABL1	Bosutinib	NCT04626024	Recruiting	Phase 2	Chronic Myeloid Leukemia	100	November 15, 2025
BCR-ABL1	Dasatinib	NCT03516279	Recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	40	August 31, 2031
BCR-ABL1	Dasatinib	NCT01746836	Recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	50	December 31, 2030
BCR-ABL1	Dasatinib	NCT05007873	Recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia	70	October 30, 2024
BCR-ABL1	Dasatinib	NCT04626024	Recruiting	Phase 2	Chronic Myeloid Leukemia	100	November 15, 2025
BCR-ABL1	Dasatinib	NCT04681820	Recruiting		CML-CP; Mutation;Suboptimal Response or Failure in TKI	200	November 2024
BCR-ABL1	Gilteritinib	NCT02115295	Recruiting	Phase 2	Acute Biphenotypic Leukemia	508	May 31, 2026
BCR-ABL1	Imatinib	NCT03516279	Recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	40	August 31, 2031
BCR-ABL1	Imatinib	NCT01746836	Recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	50	December 31, 2030
BCR-ABL1	Imatinib	NCT05071482	Recruiting	Phase 4	Acute Leukemia	238	October 30, 2025
BCR-ABL1	Imatinib	NCT04626024	Recruiting	Phase 2	Chronic Myeloid Leukemia	100	November 15, 2025
BCR-ABL1	Nilotinib	NCT03516279	Recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	40	August 31, 2031
BCR-ABL1	Nilotinib	NCT01746836	Recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	50	December 31, 2030
BCR-ABL1	Nilotinib	NCT04626024	Recruiting	Phase 2	Chronic Myeloid Leukemia	100	November 15, 2025
BCR-ABL1	Nilotinib	NCT04681820	Recruiting		CML-CP; Mutation;Suboptimal Response or Failure in TKI	200	November 2024
BCR-ABL1	Ponatinib	NCT01746836	Recruiting	Phase 2	Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	50	December 31, 2030
BCR-ABL1	Ponatinib	NCT05306301	Recruiting	Phase 2	Chemotherapy	32	July 1, 2028
BCR-ABL1	Ponatinib	NCT03263572	Recruiting	Phase 2	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	90	November 30, 2025
BCR-ABL1	Ponatinib	NCT04530565	Recruiting	Phase 3	B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1	348	July 1, 2028
BCR-ABL1	Ponatinib	NCT04747912	Recruiting	Phase 2	Lymphoblastic Leukemia	25	May 1, 2026
BCR-ABL1	Ponatinib	NCT04475731	Recruiting	Phase 2	Philadelphia-Positive ALL	67	November 2024
BCR-ABL1	Ponatinib	NCT04554459	Suspended	Phase 2	Acute Lymphoblastic Leukemia, Adult	32	July 1, 2024
BCR-ABL1	Bosutinib	NCT02228382	Terminated	Phase 4	Previously Treated PH + CML	163	October 13, 2020
BCR-ABL1	Bosutinib	NCT02906696	Terminated	Phase 2	Blasts Under 15 Percent of Bone Marrow Nucleated Cells	8	August 8, 2019
BCR-ABL1	Dasatinib	NCT02709083	Terminated	Phase 2	Chronic Myelogenous Leukemia	7	July 2018
BCR-ABL1	Dasatinib	NCT03079505	Terminated	Phase 3	Chronic Myeloid Leukemia - Chronic Phase	10	September 23, 2018
BCR-ABL1	Dasatinib	NCT01426334	Terminated	Phase 1	Accelerated Phase Chronic Myelogenous Leukemia	4
BCR-ABL1	Imatinib	NCT02709083	Terminated	Phase 2	Chronic Myelogenous Leukemia	7	July 2018
BCR-ABL1	Imatinib	NCT02086487	Terminated	Phase 4	Myeloid Leukemia, Chronic	98	August 2016
BCR-ABL1	Nilotinib	NCT02709083	Terminated	Phase 2	Chronic Myelogenous Leukemia	7	July 2018
BCR-ABL1	Nilotinib	NCT02086487	Terminated	Phase 4	Myeloid Leukemia, Chronic	98	August 2016
BCR-ABL1	Nilotinib	NCT03079505	Terminated	Phase 3	Chronic Myeloid Leukemia - Chronic Phase	10	September 23, 2018
BCR-ABL1	Ponatinib	NCT03878524	Terminated	Phase 1	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	2	December 10, 2020
BCR-ABL1	Ruxolitinib	NCT01751425	Terminated	Phase 1	Chronic Myelogenous Leukemia, BCR-ABL1 Positive	8	September 24, 2019
BCR-ABL1	Ruxolitinib	NCT03878524	Terminated	Phase 1	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	2	December 10, 2020
BCR-ABL1	Sorafenib	NCT03878524	Terminated	Phase 1	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	2	December 10, 2020
BCR-ABL1	Trametinib	NCT03878524	Terminated	Phase 1	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive	2	December 10, 2020
BCR-ABL1	Bosutinib	NCT02767063	Unknown status	Phase 1	Leukemia, Myeloid, Chronic-Phase	100	June 2023
BCR-ABL1	Dasatinib	NCT04155411	Unknown status	Phase 4	Dasatinib	65	December 1, 2023
BCR-ABL1	Dasatinib	NCT03573596	Unknown status	Phase 2	CML, Relapsed	134	February 1, 2024
BCR-ABL1	Imatinib	NCT02398825	Unknown status	Phase 2	Chronic Myeloid Leukemia	16	February 2023
BCR-ABL1	Imatinib	NCT04357613	Unknown status	Phase 2	SARS Virus	99	December 1, 2021
BCR-ABL1	Imatinib	NCT00028847	Unknown status	Phase 1	Leukemia	60
BCR-ABL1	Imatinib	NCT01901666	Unknown status	Phase 4	Chronic Myelogenous Leukemia	20	December 2014
BCR-ABL1	Imatinib	NCT01227135	Unknown status	Phase 2	Leukemia	66
BCR-ABL1	Ponatinib	NCT02398825	Unknown status	Phase 2	Chronic Myeloid Leukemia	16	February 2023
BCR-ABL1	Ponatinib	NCT02767063	Unknown status	Phase 1	Leukemia, Myeloid, Chronic-Phase	100	June 2023
BCR-ABL1	Nilotinib	NCT02973711	Withdrawn	Phase 1	Leukemia, Chronic Myeloid	0	August 2021
BCR-ABL1	Ruxolitinib	NCT02973711	Withdrawn	Phase 1	Leukemia, Chronic Myeloid	0	August 2021

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