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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: MRPL52 (NCBI Gene ID:122704)

Gene Summary

Gene Summary

Gene Information	Gene Name: MRPL52
	Gene ID: 122704
	Gene Symbol	MRPL52
	Gene ID	122704
	Gene Name	mitochondrial ribosomal protein L52
	Synonyms	-
	Cytomap	14q11.2
	Type of Gene	protein-coding
	Description	39S ribosomal protein L52, mitochondrialL52mtMRP-L52mitochondrial large ribosomal subunit protein mL52
	Modification date	20200313
	UniProtAcc	Q86TS9

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
MRPL52	(733 - 1119.25]

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Translation Studies in PubMed

We searched PubMed using 'MRPL52[title] AND translation [title] AND human.'

Gene	Title	PMID
MRPL52	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000355151	23299258	23299319	Frame-shift
ENST00000355151	23302626	23302691	Frame-shift

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
LUSC	MRPL52	-1.62632647251357	5.03439574503487e-05
LUAD	MRPL52	-3.10528494524096	5.46286040022975e-07

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
UCEC	MRPL52	-0.099952014	0.029705067

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with MRPL52 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
COAD	Cell metabolism gene	MRPL52	PSMB5	0.829551976	9.63E-85
COAD	IUPHAR	MRPL52	PSMB5	0.829551976	9.63E-85
DLBC	Cell metabolism gene	MRPL52	PSMB10	0.801864057	7.43E-12
DLBC	Cell metabolism gene	MRPL52	TOMM22	0.801874538	7.42E-12
DLBC	Cell metabolism gene	MRPL52	POLR2J	0.803524694	6.24E-12
DLBC	Cell metabolism gene	MRPL52	MMAB	0.803724912	6.11E-12
DLBC	Cell metabolism gene	MRPL52	OAZ1	0.804983103	5.35E-12
DLBC	Cell metabolism gene	MRPL52	DHRS4	0.805620238	5.00E-12
DLBC	Cell metabolism gene	MRPL52	PMVK	0.805707295	4.95E-12
DLBC	Cell metabolism gene	MRPL52	MVD	0.805746755	4.93E-12
DLBC	Cell metabolism gene	MRPL52	VKORC1	0.805846472	4.88E-12
DLBC	Cell metabolism gene	MRPL52	PSME1	0.807292319	4.18E-12
DLBC	Cell metabolism gene	MRPL52	GALK1	0.807314533	4.17E-12
DLBC	Cell metabolism gene	MRPL52	POLR2H	0.807894479	3.91E-12
DLBC	Cell metabolism gene	MRPL52	FAU	0.810741131	2.87E-12
DLBC	Cell metabolism gene	MRPL52	FPGS	0.811079916	2.76E-12
DLBC	Cell metabolism gene	MRPL52	EXOSC5	0.812237913	2.43E-12
DLBC	Cell metabolism gene	MRPL52	TIMM10	0.814485555	1.89E-12
DLBC	Cell metabolism gene	MRPL52	MED27	0.814679872	1.85E-12
DLBC	Cell metabolism gene	MRPL52	PMPCA	0.815318487	1.72E-12
DLBC	Cell metabolism gene	MRPL52	PFDN5	0.815611377	1.67E-12
DLBC	Cell metabolism gene	MRPL52	GFER	0.819182086	1.11E-12
DLBC	Cell metabolism gene	MRPL52	PSMA6	0.819598905	1.05E-12
DLBC	Cell metabolism gene	MRPL52	PGP	0.820824752	9.15E-13
DLBC	Cell metabolism gene	MRPL52	POLR2E	0.820854975	9.11E-13
DLBC	Cell metabolism gene	MRPL52	B3GAT3	0.821302448	8.65E-13
DLBC	Cell metabolism gene	MRPL52	ECHS1	0.82201274	7.96E-13
DLBC	Cell metabolism gene	MRPL52	PGLS	0.823562565	6.62E-13
DLBC	Cell metabolism gene	MRPL52	HSD17B10	0.826318052	4.76E-13
DLBC	Cell metabolism gene	MRPL52	GSTZ1	0.829018039	3.42E-13
DLBC	Cell metabolism gene	MRPL52	SNRPE	0.830071777	3.01E-13
DLBC	Cell metabolism gene	MRPL52	SEC61G	0.830566962	2.83E-13
DLBC	Cell metabolism gene	MRPL52	LSM2	0.830801746	2.75E-13
DLBC	Cell metabolism gene	MRPL52	LSM3	0.832069726	2.34E-13
DLBC	Cell metabolism gene	MRPL52	PSMB7	0.832615014	2.19E-13
DLBC	Cell metabolism gene	MRPL52	PTDSS2	0.832890908	2.11E-13
DLBC	Cell metabolism gene	MRPL52	MDH2	0.834892123	1.64E-13
DLBC	Cell metabolism gene	MRPL52	PHKG2	0.83573264	1.47E-13
DLBC	Cell metabolism gene	MRPL52	TSTA3	0.836597253	1.32E-13
DLBC	Cell metabolism gene	MRPL52	SNRPB	0.837241359	1.21E-13
DLBC	Cell metabolism gene	MRPL52	WBSCR22	0.837391406	1.19E-13
DLBC	Cell metabolism gene	MRPL52	TIMM8B	0.838213962	1.07E-13
DLBC	Cell metabolism gene	MRPL52	ACOT8	0.84137834	7.02E-14
DLBC	Cell metabolism gene	MRPL52	PSMB1	0.842094907	6.38E-14
DLBC	Cell metabolism gene	MRPL52	TIMM9	0.842101521	6.37E-14
DLBC	Cell metabolism gene	MRPL52	GEMIN7	0.843282167	5.43E-14
DLBC	Cell metabolism gene	MRPL52	PHPT1	0.846542376	3.48E-14
DLBC	Cell metabolism gene	MRPL52	SNRPD2	0.849147309	2.41E-14
DLBC	Cell metabolism gene	MRPL52	POLR2L	0.849845918	2.19E-14
DLBC	Cell metabolism gene	MRPL52	DTYMK	0.854313448	1.15E-14
DLBC	Cell metabolism gene	MRPL52	POLR2F	0.854695319	1.09E-14
DLBC	Cell metabolism gene	MRPL52	PSMA7	0.857238564	7.45E-15
DLBC	Cell metabolism gene	MRPL52	NME2	0.857663107	6.99E-15
DLBC	Cell metabolism gene	MRPL52	ATP5G1	0.862965948	3.10E-15
DLBC	Cell metabolism gene	MRPL52	DPM2	0.86297818	3.09E-15
DLBC	Cell metabolism gene	MRPL52	PSMC1	0.864994573	2.25E-15
DLBC	Cell metabolism gene	MRPL52	ITPA	0.865776613	1.98E-15
DLBC	Cell metabolism gene	MRPL52	TIMM50	0.866742513	1.70E-15
DLBC	Cell metabolism gene	MRPL52	DAD1	0.868151995	1.35E-15
DLBC	Cell metabolism gene	MRPL52	LSM4	0.870417812	9.31E-16
DLBC	Cell metabolism gene	MRPL52	POLE4	0.871340873	7.98E-16
DLBC	Cell metabolism gene	MRPL52	PSMB4	0.871434376	7.85E-16
DLBC	Cell metabolism gene	MRPL52	MIF	0.874679333	4.52E-16
DLBC	Cell metabolism gene	MRPL52	MTX1	0.877425408	2.80E-16
DLBC	Cell metabolism gene	MRPL52	UROD	0.883336657	9.60E-17
DLBC	Cell metabolism gene	MRPL52	PSMC5	0.887969612	3.98E-17
DLBC	Cell metabolism gene	MRPL52	POLR2I	0.896022643	7.83E-18
DLBC	Cell metabolism gene	MRPL52	EXOSC4	0.899108162	4.05E-18
DLBC	Cell metabolism gene	MRPL52	TIMM13	0.903886041	1.40E-18
DLBC	Cell metabolism gene	MRPL52	PSMD4	0.906619998	7.43E-19
DLBC	Cell metabolism gene	MRPL52	PSMD13	0.907233682	6.42E-19
DLBC	Cell metabolism gene	MRPL52	PSMC3	0.909493678	3.73E-19
DLBC	Cell metabolism gene	MRPL52	PSMB6	0.921905182	1.44E-20
DLBC	Cell metabolism gene	MRPL52	PSMB3	0.943553594	1.04E-23
DLBC	CGC	MRPL52	ASPSCR1	0.820199706	9.84E-13
DLBC	CGC	MRPL52	HRAS	0.832775211	2.14E-13
DLBC	CGC	MRPL52	NTHL1	0.857176764	7.51E-15
DLBC	CGC	MRPL52	COX6C	0.877023471	3.01E-16
DLBC	CGC	MRPL52	TFPT	0.889233701	3.11E-17
DLBC	Epifactor	MRPL52	EXOSC5	0.812237913	2.43E-12
DLBC	Epifactor	MRPL52	PRPF31	0.815291471	1.73E-12
DLBC	Epifactor	MRPL52	DMAP1	0.817318394	1.37E-12
DLBC	Epifactor	MRPL52	PAF1	0.821097406	8.86E-13
DLBC	Epifactor	MRPL52	SIRT6	0.847513921	3.04E-14
DLBC	Epifactor	MRPL52	RUVBL2	0.855441645	9.73E-15
DLBC	Epifactor	MRPL52	BRMS1	0.855568581	9.55E-15
DLBC	Epifactor	MRPL52	PPP4C	0.861135625	4.12E-15
DLBC	Epifactor	MRPL52	RBX1	0.867559697	1.49E-15
DLBC	Epifactor	MRPL52	ZNHIT1	0.875897795	3.66E-16
DLBC	Epifactor	MRPL52	TFPT	0.889233701	3.11E-17
DLBC	Epifactor	MRPL52	EXOSC4	0.899108162	4.05E-18
DLBC	Epifactor	MRPL52	MBD3	0.900995984	2.68E-18
DLBC	IUPHAR	MRPL52	SLC39A3	0.804027823	5.92E-12
DLBC	IUPHAR	MRPL52	SLC25A39	0.804733576	5.49E-12
DLBC	IUPHAR	MRPL52	PMVK	0.805707295	4.95E-12
DLBC	IUPHAR	MRPL52	MVD	0.805746755	4.93E-12
DLBC	IUPHAR	MRPL52	VKORC1	0.805846472	4.88E-12
DLBC	IUPHAR	MRPL52	ATP6V1E1	0.8072996	4.17E-12
DLBC	IUPHAR	MRPL52	MFSD2B	0.814091558	1.98E-12
DLBC	IUPHAR	MRPL52	HRAS	0.832775211	2.14E-13
DLBC	IUPHAR	MRPL52	SLC25A26	0.835055884	1.60E-13
DLBC	IUPHAR	MRPL52	PHKG2	0.83573264	1.47E-13
DLBC	IUPHAR	MRPL52	BIRC5	0.840149866	8.26E-14
DLBC	IUPHAR	MRPL52	PSMB1	0.842094907	6.38E-14
DLBC	IUPHAR	MRPL52	SIRT6	0.847513921	3.04E-14
DLBC	IUPHAR	MRPL52	MPDU1	0.871364427	7.95E-16
DLBC	IUPHAR	MRPL52	PSMB6	0.921905182	1.44E-20
DLBC	Kinase	MRPL52	PHKG2	0.83573264	1.47E-13
DLBC	TF	MRPL52	THAP3	0.817611735	1.33E-12
DLBC	TF	MRPL52	ZNF653	0.821478018	8.47E-13
DLBC	TF	MRPL52	THAP7	0.833221046	2.03E-13
DLBC	TF	MRPL52	THAP4	0.851842478	1.64E-14
DLBC	TF	MRPL52	NME2	0.857663107	6.99E-15
DLBC	TF	MRPL52	PIN1	0.898875455	4.26E-18
DLBC	TF	MRPL52	MBD3	0.900995984	2.68E-18
DLBC	TSG	MRPL52	STUB1	0.831736654	2.44E-13
DLBC	TSG	MRPL52	SIRT6	0.847513921	3.04E-14
DLBC	TSG	MRPL52	BRMS1	0.855568581	9.55E-15
DLBC	TSG	MRPL52	PHB	0.877062187	2.99E-16
DLBC	TSG	MRPL52	TSSC4	0.884374764	7.91E-17
DLBC	TSG	MRPL52	PIN1	0.898875455	4.26E-18
DLBC	TSG	MRPL52	GADD45GIP1	0.936195744	1.61E-22
ESCA	Cell metabolism gene	MRPL52	DAD1	0.814889598	7.84E-48
GBM	Cell metabolism gene	MRPL52	PSMB5	0.813548655	7.04E-42
GBM	Cell metabolism gene	MRPL52	PSMA6	0.826443888	2.86E-44
GBM	Cell metabolism gene	MRPL52	TIMM9	0.845900237	2.81E-48
GBM	Cell metabolism gene	MRPL52	DAD1	0.86846075	1.10E-53
GBM	IUPHAR	MRPL52	PSMB5	0.813548655	7.04E-42
KIRP	Cell metabolism gene	MRPL52	MTX1	0.811529567	6.78E-77
KIRP	Cell metabolism gene	MRPL52	POLR2I	0.817549931	6.26E-79
KIRP	TSG	MRPL52	GADD45GIP1	0.826127159	5.80E-82
LIHC	Cell metabolism gene	MRPL52	PFDN5	0.809210625	2.75E-99
LIHC	TSG	MRPL52	GADD45GIP1	0.825928261	7.72E-107
LUAD	Cell metabolism gene	MRPL52	DAD1	0.800880888	6.14E-130
LUAD	Cell metabolism gene	MRPL52	PSMB5	0.812514303	1.20E-136
LUAD	IUPHAR	MRPL52	PSMB5	0.812514303	1.20E-136
MESO	Cell metabolism gene	MRPL52	PSMC1	0.827948515	4.62E-23
OV	Cell metabolism gene	MRPL52	DAD1	0.872694225	2.80E-97
PAAD	Cell metabolism gene	MRPL52	LSM4	0.804828344	7.17E-43
PCPG	Cell metabolism gene	MRPL52	SNRPD2	0.808903281	1.53E-44
PCPG	TSG	MRPL52	GADD45GIP1	0.828365803	1.95E-48
PRAD	Cell metabolism gene	MRPL52	PSMB7	0.800312208	7.77E-124
PRAD	Cell metabolism gene	MRPL52	GPX4	0.800498046	6.19E-124
PRAD	Cell metabolism gene	MRPL52	LCMT1	0.800654623	5.11E-124
PRAD	Cell metabolism gene	MRPL52	LSM4	0.800778866	4.39E-124
PRAD	Cell metabolism gene	MRPL52	SNRPD2	0.800866116	3.94E-124
PRAD	Cell metabolism gene	MRPL52	DHRS4L2	0.801169772	2.72E-124
PRAD	Cell metabolism gene	MRPL52	GEMIN7	0.80225191	7.17E-125
PRAD	Cell metabolism gene	MRPL52	B4GALT7	0.802594915	4.70E-125
PRAD	Cell metabolism gene	MRPL52	HSD17B10	0.802917807	3.15E-125
PRAD	Cell metabolism gene	MRPL52	DPM2	0.806076246	6.06E-127
PRAD	Cell metabolism gene	MRPL52	PSMC3	0.813046338	7.60E-131
PRAD	Cell metabolism gene	MRPL52	POLR2F	0.816347946	9.45E-133
PRAD	Cell metabolism gene	MRPL52	UROD	0.816496582	7.74E-133
PRAD	Cell metabolism gene	MRPL52	PHPT1	0.816713962	5.78E-133
PRAD	Cell metabolism gene	MRPL52	TIMM17B	0.817428723	2.20E-133
PRAD	Cell metabolism gene	MRPL52	PSMC5	0.819320394	1.69E-134
PRAD	Cell metabolism gene	MRPL52	PSMC1	0.820826846	2.13E-135
PRAD	Cell metabolism gene	MRPL52	PMVK	0.821755249	5.89E-136
PRAD	Cell metabolism gene	MRPL52	FAU	0.822054547	3.89E-136
PRAD	Cell metabolism gene	MRPL52	PPCDC	0.824448242	1.36E-137
PRAD	Cell metabolism gene	MRPL52	DPM3	0.827011243	3.54E-139
PRAD	Cell metabolism gene	MRPL52	POLR2L	0.828291002	5.59E-140
PRAD	Cell metabolism gene	MRPL52	IDH3G	0.828701824	3.08E-140
PRAD	Cell metabolism gene	MRPL52	GPX1	0.841988518	5.45E-149
PRAD	Cell metabolism gene	MRPL52	PSMB3	0.844091563	1.89E-150
PRAD	Cell metabolism gene	MRPL52	PFDN5	0.84529011	2.72E-151
PRAD	Cell metabolism gene	MRPL52	POLR2I	0.870669613	5.31E-171
PRAD	CGC	MRPL52	MAP2K2	0.809575646	6.98E-129
PRAD	CGC	MRPL52	ASPSCR1	0.81841467	5.79E-134
PRAD	Epifactor	MRPL52	C17orf49	0.802365028	6.24E-125
PRAD	Epifactor	MRPL52	TAF10	0.805599725	1.10E-126
PRAD	Epifactor	MRPL52	RBX1	0.813384109	4.87E-131
PRAD	Epifactor	MRPL52	SIRT6	0.815966103	1.58E-132
PRAD	Epifactor	MRPL52	BRMS1	0.827425309	1.95E-139
PRAD	Epifactor	MRPL52	ZNHIT1	0.860319937	1.70E-162
PRAD	IUPHAR	MRPL52	MAP2K2	0.809575646	6.98E-129
PRAD	IUPHAR	MRPL52	SIRT6	0.815966103	1.58E-132
PRAD	IUPHAR	MRPL52	PMVK	0.821755249	5.89E-136
PRAD	Kinase	MRPL52	MAP2K2	0.809575646	6.98E-129
PRAD	TF	MRPL52	ZNF32	0.820017979	6.48E-135
PRAD	TF	MRPL52	THAP3	0.831007682	1.06E-141
PRAD	TF	MRPL52	THAP7	0.842176991	4.04E-149
PRAD	TSG	MRPL52	PHB	0.803805634	1.04E-125
PRAD	TSG	MRPL52	STUB1	0.807233612	1.40E-127
PRAD	TSG	MRPL52	TSSC4	0.807468045	1.04E-127
PRAD	TSG	MRPL52	SIRT6	0.815966103	1.58E-132
PRAD	TSG	MRPL52	BRMS1	0.827425309	1.95E-139
PRAD	TSG	MRPL52	GADD45GIP1	0.908015617	3.24E-209
READ	TSG	MRPL52	GADD45GIP1	0.806485935	3.01E-25
STAD	Cell metabolism gene	MRPL52	DAD1	0.803372967	6.45E-103
TGCT	Cell metabolism gene	MRPL52	NT5C	0.831536891	3.66E-41
TGCT	IUPHAR	MRPL52	NT5C	0.831536891	3.66E-41
THCA	Cell metabolism gene	MRPL52	PSMB4	0.808048489	4.27E-133
THCA	Cell metabolism gene	MRPL52	B4GALT7	0.808413284	2.63E-133
THCA	Cell metabolism gene	MRPL52	FAU	0.814395838	7.92E-137
THCA	Cell metabolism gene	MRPL52	NT5C	0.824137408	7.64E-143
THCA	Cell metabolism gene	MRPL52	PSMD13	0.826261021	3.33E-144
THCA	Cell metabolism gene	MRPL52	MTX1	0.831347582	1.54E-147
THCA	Cell metabolism gene	MRPL52	PSMC3	0.832531344	2.48E-148
THCA	Cell metabolism gene	MRPL52	PFDN5	0.832969954	1.25E-148
THCA	Cell metabolism gene	MRPL52	POLR2J	0.833230977	8.37E-149
THCA	Cell metabolism gene	MRPL52	ACOT8	0.834492799	1.17E-149
THCA	Cell metabolism gene	MRPL52	TIMM13	0.838824666	1.19E-152
THCA	Cell metabolism gene	MRPL52	ITPA	0.842835576	1.67E-155
THCA	Cell metabolism gene	MRPL52	LSM4	0.843168423	9.60E-156
THCA	Cell metabolism gene	MRPL52	PSMB1	0.843373819	6.82E-156
THCA	Cell metabolism gene	MRPL52	TIMM8B	0.846081033	7.18E-158
THCA	Cell metabolism gene	MRPL52	APRT	0.846197462	5.89E-158
THCA	Cell metabolism gene	MRPL52	SNRPD2	0.848787984	6.91E-160
THCA	Cell metabolism gene	MRPL52	PSMB7	0.849822782	1.14E-160
THCA	Cell metabolism gene	MRPL52	PSMC5	0.852561811	9.16E-163
THCA	Cell metabolism gene	MRPL52	POLR2L	0.853122797	3.37E-163
THCA	Cell metabolism gene	MRPL52	PHPT1	0.857268311	1.81E-166
THCA	Cell metabolism gene	MRPL52	PSMC1	0.864096894	4.37E-172
THCA	Cell metabolism gene	MRPL52	DPM3	0.869900504	4.18E-177
THCA	Cell metabolism gene	MRPL52	POLR2I	0.870800301	6.62E-178
THCA	Cell metabolism gene	MRPL52	EXOSC4	0.876211465	7.59E-183
THCA	Cell metabolism gene	MRPL52	PSMB6	0.877708967	2.96E-184
THCA	Cell metabolism gene	MRPL52	PSMB3	0.884290576	1.13E-190
THCA	CGC	MRPL52	COX6C	0.8146559	5.53E-137
THCA	CGC	MRPL52	TFPT	0.819924877	3.38E-140
THCA	CGC	MRPL52	HRAS	0.82552604	9.90E-144
THCA	CGC	MRPL52	ASPSCR1	0.837115083	1.84E-151
THCA	Epifactor	MRPL52	TFPT	0.819924877	3.38E-140
THCA	Epifactor	MRPL52	RUVBL2	0.844597093	8.80E-157
THCA	Epifactor	MRPL52	BRMS1	0.858116481	3.77E-167
THCA	Epifactor	MRPL52	EXOSC4	0.876211465	7.59E-183
THCA	Epifactor	MRPL52	ZNHIT1	0.897452041	9.19E-205
THCA	IUPHAR	MRPL52	PPIA	0.802233484	8.49E-130
THCA	IUPHAR	MRPL52	NT5C	0.824137408	7.64E-143
THCA	IUPHAR	MRPL52	HRAS	0.82552604	9.90E-144
THCA	IUPHAR	MRPL52	PSMB1	0.843373819	6.82E-156
THCA	IUPHAR	MRPL52	PSMB6	0.877708967	2.96E-184
THCA	TF	MRPL52	ZNF428	0.804471625	4.70E-131
THCA	TF	MRPL52	ZNF688	0.808351981	2.85E-133
THCA	TSG	MRPL52	STUB1	0.801093111	3.65E-129
THCA	TSG	MRPL52	TSSC4	0.807071534	1.56E-132
THCA	TSG	MRPL52	AIP	0.80876492	1.65E-133
THCA	TSG	MRPL52	PARK7	0.832978688	1.24E-148
THCA	TSG	MRPL52	BRMS1	0.858116481	3.77E-167
THCA	TSG	MRPL52	GADD45GIP1	0.891207204	7.50E-198
THYM	Cell metabolism gene	MRPL52	SLC25A11	0.800003915	2.16E-28
THYM	Cell metabolism gene	MRPL52	PREB	0.800278781	2.00E-28
THYM	Cell metabolism gene	MRPL52	SUCLG1	0.801842877	1.32E-28
THYM	Cell metabolism gene	MRPL52	ATIC	0.804373147	6.60E-29
THYM	Cell metabolism gene	MRPL52	NOP56	0.804464282	6.43E-29
THYM	Cell metabolism gene	MRPL52	GCDH	0.80658758	3.58E-29
THYM	Cell metabolism gene	MRPL52	SMPD2	0.806872876	3.30E-29
THYM	Cell metabolism gene	MRPL52	DOHH	0.809094241	1.77E-29
THYM	Cell metabolism gene	MRPL52	POLA2	0.811284938	9.51E-30
THYM	Cell metabolism gene	MRPL52	PCYT2	0.812358051	6.99E-30
THYM	Cell metabolism gene	MRPL52	PSMA7	0.813992926	4.35E-30
THYM	Cell metabolism gene	MRPL52	CYC1	0.814442518	3.82E-30
THYM	Cell metabolism gene	MRPL52	PPCDC	0.814798302	3.44E-30
THYM	Cell metabolism gene	MRPL52	PSMA6	0.815203645	3.06E-30
THYM	Cell metabolism gene	MRPL52	PSMA5	0.81909182	9.66E-31
THYM	Cell metabolism gene	MRPL52	PFDN6	0.821043925	5.36E-31
THYM	Cell metabolism gene	MRPL52	EXOSC1	0.823547077	2.49E-31
THYM	Cell metabolism gene	MRPL52	SRM	0.823547896	2.49E-31
THYM	Cell metabolism gene	MRPL52	PSMC4	0.824389694	1.92E-31
THYM	Cell metabolism gene	MRPL52	NME1	0.825166188	1.51E-31
THYM	Cell metabolism gene	MRPL52	POLD4	0.826072795	1.14E-31
THYM	Cell metabolism gene	MRPL52	POLE4	0.82645433	1.01E-31
THYM	Cell metabolism gene	MRPL52	POLR3K	0.82664923	9.49E-32
THYM	Cell metabolism gene	MRPL52	IDH3B	0.8274948	7.27E-32
THYM	Cell metabolism gene	MRPL52	SNRPF	0.83007739	3.19E-32
THYM	Cell metabolism gene	MRPL52	ALG3	0.831322559	2.14E-32
THYM	Cell metabolism gene	MRPL52	DAD1	0.831366532	2.10E-32
THYM	Cell metabolism gene	MRPL52	PTGES2	0.833061094	1.21E-32
THYM	Cell metabolism gene	MRPL52	PSME1	0.833768524	9.60E-33
THYM	Cell metabolism gene	MRPL52	UROD	0.835860231	4.80E-33
THYM	Cell metabolism gene	MRPL52	FPGS	0.836110995	4.41E-33
THYM	Cell metabolism gene	MRPL52	GSTZ1	0.837375712	2.88E-33
THYM	Cell metabolism gene	MRPL52	SNRPD1	0.838932352	1.70E-33
THYM	Cell metabolism gene	MRPL52	COX17	0.839583174	1.36E-33
THYM	Cell metabolism gene	MRPL52	TAZ	0.839681037	1.32E-33
THYM	Cell metabolism gene	MRPL52	TXN	0.841534041	6.95E-34
THYM	Cell metabolism gene	MRPL52	SEC61B	0.842050403	5.81E-34
THYM	Cell metabolism gene	MRPL52	SSR2	0.844424201	2.52E-34
THYM	Cell metabolism gene	MRPL52	TSTA3	0.845366945	1.80E-34
THYM	Cell metabolism gene	MRPL52	PFDN5	0.84655482	1.18E-34
THYM	Cell metabolism gene	MRPL52	PSMB2	0.84772568	7.72E-35
THYM	Cell metabolism gene	MRPL52	TOMM22	0.847772467	7.59E-35
THYM	Cell metabolism gene	MRPL52	HMBS	0.84894935	4.94E-35
THYM	Cell metabolism gene	MRPL52	EXOSC5	0.851128856	2.21E-35
THYM	Cell metabolism gene	MRPL52	LSM5	0.851940164	1.64E-35
THYM	Cell metabolism gene	MRPL52	UROS	0.851948059	1.63E-35
THYM	Cell metabolism gene	MRPL52	PSMD8	0.855029988	5.08E-36
THYM	Cell metabolism gene	MRPL52	PSMA4	0.855651702	4.00E-36
THYM	Cell metabolism gene	MRPL52	MED27	0.855754791	3.85E-36
THYM	Cell metabolism gene	MRPL52	SNRPD3	0.856093464	3.38E-36
THYM	Cell metabolism gene	MRPL52	PSMC5	0.856174975	3.27E-36
THYM	Cell metabolism gene	MRPL52	GMPPA	0.856189944	3.25E-36
THYM	Cell metabolism gene	MRPL52	HMOX2	0.856915221	2.46E-36
THYM	Cell metabolism gene	MRPL52	DGAT1	0.857451259	1.99E-36
THYM	Cell metabolism gene	MRPL52	DHRS4	0.85820696	1.48E-36
THYM	Cell metabolism gene	MRPL52	MIF	0.858446726	1.35E-36
THYM	Cell metabolism gene	MRPL52	IDH3G	0.858492996	1.33E-36
THYM	Cell metabolism gene	MRPL52	POLR2F	0.858870041	1.14E-36
THYM	Cell metabolism gene	MRPL52	GSS	0.858924545	1.12E-36
THYM	Cell metabolism gene	MRPL52	OAZ1	0.860723537	5.48E-37
THYM	Cell metabolism gene	MRPL52	GALK1	0.864122991	1.38E-37
THYM	Cell metabolism gene	MRPL52	DHRS4L2	0.864333344	1.27E-37
THYM	Cell metabolism gene	MRPL52	FAU	0.865933334	6.54E-38
THYM	Cell metabolism gene	MRPL52	ATP5G1	0.866249755	5.73E-38
THYM	Cell metabolism gene	MRPL52	LSM2	0.86716203	3.91E-38
THYM	Cell metabolism gene	MRPL52	GEMIN6	0.867335111	3.64E-38
THYM	Cell metabolism gene	MRPL52	SNRPE	0.867495	3.40E-38
THYM	Cell metabolism gene	MRPL52	PMPCA	0.869109361	1.71E-38
THYM	Cell metabolism gene	MRPL52	PSMB4	0.869785985	1.28E-38
THYM	Cell metabolism gene	MRPL52	PSMB1	0.869998118	1.17E-38
THYM	Cell metabolism gene	MRPL52	MVD	0.870735057	8.51E-39
THYM	Cell metabolism gene	MRPL52	LSM3	0.8726857	3.63E-39
THYM	Cell metabolism gene	MRPL52	TBCB	0.873019442	3.13E-39
THYM	Cell metabolism gene	MRPL52	SNRPB	0.87323029	2.86E-39
THYM	Cell metabolism gene	MRPL52	DTYMK	0.876237569	7.42E-40
THYM	Cell metabolism gene	MRPL52	PAFAH1B3	0.878533219	2.59E-40
THYM	Cell metabolism gene	MRPL52	POLD2	0.880236655	1.17E-40
THYM	Cell metabolism gene	MRPL52	NANS	0.881530795	6.34E-41
THYM	Cell metabolism gene	MRPL52	ITPA	0.882326816	4.34E-41
THYM	Cell metabolism gene	MRPL52	DGUOK	0.882573868	3.85E-41
THYM	Cell metabolism gene	MRPL52	PSMB10	0.885845662	7.82E-42
THYM	Cell metabolism gene	MRPL52	PSMB6	0.888450286	2.12E-42
THYM	Cell metabolism gene	MRPL52	DPM2	0.888486727	2.08E-42
THYM	Cell metabolism gene	MRPL52	TIMM10	0.891727331	3.92E-43
THYM	Cell metabolism gene	MRPL52	SLC27A5	0.895808222	4.43E-44
THYM	Cell metabolism gene	MRPL52	PSME2	0.897302066	1.95E-44
THYM	Cell metabolism gene	MRPL52	GEMIN7	0.899130537	7.01E-45
THYM	Cell metabolism gene	MRPL52	MTX1	0.900402997	3.40E-45
THYM	Cell metabolism gene	MRPL52	SEC61G	0.903778765	4.76E-46
THYM	Cell metabolism gene	MRPL52	PGP	0.904505361	3.09E-46
THYM	Cell metabolism gene	MRPL52	PSMD13	0.90507198	2.20E-46
THYM	Cell metabolism gene	MRPL52	HSD17B10	0.905297862	1.92E-46
THYM	Cell metabolism gene	MRPL52	PGLS	0.906002396	1.25E-46
THYM	Cell metabolism gene	MRPL52	PHKG2	0.91044749	7.84E-48
THYM	Cell metabolism gene	MRPL52	LSM4	0.91132145	4.47E-48
THYM	Cell metabolism gene	MRPL52	WBSCR22	0.911388219	4.28E-48
THYM	Cell metabolism gene	MRPL52	DPM3	0.912304651	2.36E-48
THYM	Cell metabolism gene	MRPL52	EXOSC4	0.915725896	2.40E-49
THYM	Cell metabolism gene	MRPL52	TOMM40	0.91745773	7.28E-50
THYM	Cell metabolism gene	MRPL52	POLR2I	0.918928093	2.59E-50
THYM	Cell metabolism gene	MRPL52	PSMC3	0.920622276	7.68E-51
THYM	Cell metabolism gene	MRPL52	TIMM17B	0.92100754	5.80E-51
THYM	Cell metabolism gene	MRPL52	EBP	0.924380442	4.68E-52
THYM	Cell metabolism gene	MRPL52	PSMC1	0.925908511	1.44E-52
THYM	Cell metabolism gene	MRPL52	APRT	0.927343135	4.65E-53
THYM	Cell metabolism gene	MRPL52	PSMD4	0.928666571	1.61E-53
THYM	Cell metabolism gene	MRPL52	GUK1	0.930778132	2.82E-54
THYM	Cell metabolism gene	MRPL52	POLR2J	0.930978299	2.39E-54
THYM	Cell metabolism gene	MRPL52	POLR2H	0.931520725	1.51E-54
THYM	Cell metabolism gene	MRPL52	TIMM8B	0.936119134	2.68E-56
THYM	Cell metabolism gene	MRPL52	TIMM13	0.94056889	4.02E-58
THYM	Cell metabolism gene	MRPL52	PSMB7	0.946931639	5.44E-61
THYM	Cell metabolism gene	MRPL52	SNRPD2	0.952874191	5.22E-64
THYM	Cell metabolism gene	MRPL52	TIMM50	0.953135951	3.77E-64
THYM	Cell metabolism gene	MRPL52	ACOT8	0.95588234	1.09E-65
THYM	Cell metabolism gene	MRPL52	PSMB3	0.956387296	5.55E-66
THYM	CGC	MRPL52	ATIC	0.804373147	6.60E-29
THYM	CGC	MRPL52	RECQL4	0.808377135	2.17E-29
THYM	CGC	MRPL52	MGMT	0.817220439	1.69E-30
THYM	CGC	MRPL52	ASPSCR1	0.823615276	2.44E-31
THYM	CGC	MRPL52	MAP2K2	0.829479429	3.87E-32
THYM	CGC	MRPL52	RBM10	0.863503338	1.78E-37
THYM	CGC	MRPL52	SDHAF2	0.887400191	3.60E-42
THYM	CGC	MRPL52	COX6C	0.895505472	5.22E-44
THYM	CGC	MRPL52	TFPT	0.926894477	6.64E-53
THYM	Epifactor	MRPL52	SS18L2	0.800398396	1.94E-28
THYM	Epifactor	MRPL52	ACTR5	0.804354947	6.63E-29
THYM	Epifactor	MRPL52	CXXC1	0.804653259	6.11E-29
THYM	Epifactor	MRPL52	PPM1G	0.815403603	2.88E-30
THYM	Epifactor	MRPL52	HMG20B	0.82093606	5.54E-31
THYM	Epifactor	MRPL52	EXOSC1	0.823547077	2.49E-31
THYM	Epifactor	MRPL52	NOC2L	0.831187133	2.23E-32
THYM	Epifactor	MRPL52	PRMT1	0.832463147	1.47E-32
THYM	Epifactor	MRPL52	HIST2H2AC	0.834918247	6.56E-33
THYM	Epifactor	MRPL52	EXOSC5	0.851128856	2.21E-35
THYM	Epifactor	MRPL52	MBD3	0.85174568	1.76E-35
THYM	Epifactor	MRPL52	CCDC101	0.857731058	1.79E-36
THYM	Epifactor	MRPL52	RRP8	0.866262349	5.70E-38
THYM	Epifactor	MRPL52	PAF1	0.870109912	1.12E-38
THYM	Epifactor	MRPL52	C17orf49	0.873538852	2.49E-39
THYM	Epifactor	MRPL52	FBL	0.873886758	2.13E-39
THYM	Epifactor	MRPL52	LAS1L	0.881329617	6.98E-41
THYM	Epifactor	MRPL52	ZGPAT	0.88320407	2.84E-41
THYM	Epifactor	MRPL52	INO80E	0.885443639	9.53E-42
THYM	Epifactor	MRPL52	CDK5	0.887775089	2.98E-42
THYM	Epifactor	MRPL52	RUVBL2	0.89735669	1.89E-44
THYM	Epifactor	MRPL52	PPP4C	0.90743827	5.20E-47
THYM	Epifactor	MRPL52	EXOSC4	0.915725896	2.40E-49
THYM	Epifactor	MRPL52	TAF10	0.923472264	9.33E-52
THYM	Epifactor	MRPL52	TFPT	0.926894477	6.64E-53
THYM	Epifactor	MRPL52	SIRT6	0.927005729	6.08E-53
THYM	Epifactor	MRPL52	ZNHIT1	0.943094729	3.20E-59
THYM	Epifactor	MRPL52	PRPF31	0.944454071	7.81E-60
THYM	Epifactor	MRPL52	BRMS1	0.950090763	1.50E-62
THYM	IUPHAR	MRPL52	SLC25A11	0.800003915	2.16E-28
THYM	IUPHAR	MRPL52	UCHL3	0.801021711	1.64E-28
THYM	IUPHAR	MRPL52	ECE2	0.805980911	4.23E-29
THYM	IUPHAR	MRPL52	FKBP1A	0.806045133	4.16E-29
THYM	IUPHAR	MRPL52	SMPD2	0.806872876	3.30E-29
THYM	IUPHAR	MRPL52	MPDU1	0.807315787	2.92E-29
THYM	IUPHAR	MRPL52	MMP24	0.814913924	3.33E-30
THYM	IUPHAR	MRPL52	ABCB8	0.819234735	9.26E-31
THYM	IUPHAR	MRPL52	DYRK4	0.821034336	5.38E-31
THYM	IUPHAR	MRPL52	MAP2K2	0.829479429	3.87E-32
THYM	IUPHAR	MRPL52	EGLN2	0.83170653	1.88E-32
THYM	IUPHAR	MRPL52	PRMT1	0.832463147	1.47E-32
THYM	IUPHAR	MRPL52	PTGES2	0.833061094	1.21E-32
THYM	IUPHAR	MRPL52	ADCK5	0.8389651	1.68E-33
THYM	IUPHAR	MRPL52	ATP6V0B	0.839751865	1.29E-33
THYM	IUPHAR	MRPL52	PSMB2	0.84772568	7.72E-35
THYM	IUPHAR	MRPL52	ATG4B	0.849541483	3.98E-35
THYM	IUPHAR	MRPL52	HMOX2	0.856915221	2.46E-36
THYM	IUPHAR	MRPL52	DGAT1	0.857451259	1.99E-36
THYM	IUPHAR	MRPL52	SLC39A3	0.860574119	5.82E-37
THYM	IUPHAR	MRPL52	PSMB1	0.869998118	1.17E-38
THYM	IUPHAR	MRPL52	MVD	0.870735057	8.51E-39
THYM	IUPHAR	MRPL52	PPIA	0.88378755	2.14E-41
THYM	IUPHAR	MRPL52	CDK5	0.887775089	2.98E-42
THYM	IUPHAR	MRPL52	PSMB6	0.888450286	2.12E-42
THYM	IUPHAR	MRPL52	SLC27A5	0.895808222	4.43E-44
THYM	IUPHAR	MRPL52	PHKG2	0.91044749	7.84E-48
THYM	IUPHAR	MRPL52	SIRT6	0.927005729	6.08E-53
THYM	Kinase	MRPL52	DYRK4	0.821034336	5.38E-31
THYM	Kinase	MRPL52	MAP2K2	0.829479429	3.87E-32
THYM	Kinase	MRPL52	ADCK5	0.8389651	1.68E-33
THYM	Kinase	MRPL52	FASTK	0.843290361	3.76E-34
THYM	Kinase	MRPL52	ADCK4	0.849407529	4.18E-35
THYM	Kinase	MRPL52	CDK5	0.887775089	2.98E-42
THYM	Kinase	MRPL52	PHKG2	0.91044749	7.84E-48
THYM	TF	MRPL52	PREB	0.800278781	2.00E-28
THYM	TF	MRPL52	AKAP8L	0.802733519	1.03E-28
THYM	TF	MRPL52	CXXC1	0.804653259	6.11E-29
THYM	TF	MRPL52	GTF3A	0.807513073	2.76E-29
THYM	TF	MRPL52	SNAPC2	0.810830942	1.08E-29
THYM	TF	MRPL52	MYPOP	0.813381372	5.20E-30
THYM	TF	MRPL52	ZNF511	0.814196165	4.10E-30
THYM	TF	MRPL52	THAP3	0.81939755	8.82E-31
THYM	TF	MRPL52	HMG20B	0.82093606	5.54E-31
THYM	TF	MRPL52	THAP8	0.827822278	6.55E-32
THYM	TF	MRPL52	THAP7	0.829618987	3.70E-32
THYM	TF	MRPL52	ZNF524	0.830978374	2.39E-32
THYM	TF	MRPL52	ZNF581	0.836292291	4.15E-33
THYM	TF	MRPL52	DNTTIP1	0.837396178	2.86E-33
THYM	TF	MRPL52	ZNF668	0.844799754	2.21E-34
THYM	TF	MRPL52	PIN1	0.84648233	1.21E-34
THYM	TF	MRPL52	ZNF32	0.846630061	1.15E-34
THYM	TF	MRPL52	THYN1	0.847030358	9.93E-35
THYM	TF	MRPL52	ETV2	0.849185584	4.53E-35
THYM	TF	MRPL52	MBD3	0.85174568	1.76E-35
THYM	TF	MRPL52	ZNF444	0.856267294	3.16E-36
THYM	TF	MRPL52	IRF3	0.859021519	1.08E-36
THYM	TF	MRPL52	ZNF428	0.866465121	5.24E-38
THYM	TF	MRPL52	GLI4	0.869605013	1.39E-38
THYM	TF	MRPL52	RBCK1	0.873683074	2.34E-39
THYM	TF	MRPL52	USF1	0.875051885	1.27E-39
THYM	TF	MRPL52	ZGPAT	0.88320407	2.84E-41
THYM	TF	MRPL52	ZNF688	0.89417128	1.07E-43
THYM	TF	MRPL52	ZNF787	0.897185298	2.08E-44
THYM	TF	MRPL52	DRAP1	0.907292386	5.69E-47
THYM	TSG	MRPL52	AIP	0.800991891	1.66E-28
THYM	TSG	MRPL52	GLTSCR2	0.80327541	8.91E-29
THYM	TSG	MRPL52	TUSC2	0.805430283	4.93E-29
THYM	TSG	MRPL52	HTRA2	0.815184751	3.08E-30
THYM	TSG	MRPL52	NME1	0.825166188	1.51E-31
THYM	TSG	MRPL52	GNB2L1	0.828956416	4.57E-32
THYM	TSG	MRPL52	PFN1	0.836317545	4.12E-33
THYM	TSG	MRPL52	STUB1	0.839323516	1.49E-33
THYM	TSG	MRPL52	MAD1L1	0.840499475	9.94E-34
THYM	TSG	MRPL52	ZNF668	0.844799754	2.21E-34
THYM	TSG	MRPL52	PIN1	0.84648233	1.21E-34
THYM	TSG	MRPL52	ST20	0.848927606	4.98E-35
THYM	TSG	MRPL52	GABARAP	0.849099708	4.68E-35
THYM	TSG	MRPL52	IRF3	0.859021519	1.08E-36
THYM	TSG	MRPL52	PARK7	0.860320607	6.44E-37
THYM	TSG	MRPL52	NPRL2	0.895929914	4.14E-44
THYM	TSG	MRPL52	TSSC4	0.906100194	1.18E-46
THYM	TSG	MRPL52	GADD45GIP1	0.921871563	3.08E-51
THYM	TSG	MRPL52	SIRT6	0.927005729	6.08E-53
THYM	TSG	MRPL52	BRMS1	0.950090763	1.50E-62
UCEC	Cell metabolism gene	MRPL52	TIMM8B	0.804712476	6.02E-47
UCEC	Cell metabolism gene	MRPL52	PGP	0.811607504	2.44E-48
UCEC	Cell metabolism gene	MRPL52	PSMC1	0.820385665	3.39E-50
UCEC	Cell metabolism gene	MRPL52	POLR2L	0.831757421	9.27E-53
UCEC	Cell metabolism gene	MRPL52	EXOSC4	0.844847496	5.86E-56
UCEC	Epifactor	MRPL52	BRMS1	0.811336177	2.78E-48
UCEC	Epifactor	MRPL52	ZNHIT1	0.814070185	7.53E-49
UCEC	Epifactor	MRPL52	EXOSC4	0.844847496	5.86E-56
UCEC	TSG	MRPL52	BRMS1	0.811336177	2.78E-48
UCEC	TSG	MRPL52	GADD45GIP1	0.846746282	1.90E-56
UCS	Cell metabolism gene	MRPL52	SLC25A11	0.800003915	2.16E-28
UCS	Cell metabolism gene	MRPL52	PREB	0.800278781	2.00E-28
UCS	Cell metabolism gene	MRPL52	SUCLG1	0.801842877	1.32E-28
UCS	Cell metabolism gene	MRPL52	ATIC	0.804373147	6.60E-29
UCS	Cell metabolism gene	MRPL52	NOP56	0.804464282	6.43E-29
UCS	Cell metabolism gene	MRPL52	GCDH	0.80658758	3.58E-29
UCS	Cell metabolism gene	MRPL52	SMPD2	0.806872876	3.30E-29
UCS	Cell metabolism gene	MRPL52	DOHH	0.809094241	1.77E-29
UCS	Cell metabolism gene	MRPL52	POLA2	0.811284938	9.51E-30
UCS	Cell metabolism gene	MRPL52	PCYT2	0.812358051	6.99E-30
UCS	Cell metabolism gene	MRPL52	PSMA7	0.813992926	4.35E-30
UCS	Cell metabolism gene	MRPL52	CYC1	0.814442518	3.82E-30
UCS	Cell metabolism gene	MRPL52	PPCDC	0.814798302	3.44E-30
UCS	Cell metabolism gene	MRPL52	PSMA6	0.815203645	3.06E-30
UCS	Cell metabolism gene	MRPL52	PSMA5	0.81909182	9.66E-31
UCS	Cell metabolism gene	MRPL52	PFDN6	0.821043925	5.36E-31
UCS	Cell metabolism gene	MRPL52	EXOSC1	0.823547077	2.49E-31
UCS	Cell metabolism gene	MRPL52	SRM	0.823547896	2.49E-31
UCS	Cell metabolism gene	MRPL52	PSMC4	0.824389694	1.92E-31
UCS	Cell metabolism gene	MRPL52	NME1	0.825166188	1.51E-31
UCS	Cell metabolism gene	MRPL52	POLD4	0.826072795	1.14E-31
UCS	Cell metabolism gene	MRPL52	POLE4	0.82645433	1.01E-31
UCS	Cell metabolism gene	MRPL52	POLR3K	0.82664923	9.49E-32
UCS	Cell metabolism gene	MRPL52	IDH3B	0.8274948	7.27E-32
UCS	Cell metabolism gene	MRPL52	SNRPF	0.83007739	3.19E-32
UCS	Cell metabolism gene	MRPL52	ALG3	0.831322559	2.14E-32
UCS	Cell metabolism gene	MRPL52	DAD1	0.831366532	2.10E-32
UCS	Cell metabolism gene	MRPL52	PTGES2	0.833061094	1.21E-32
UCS	Cell metabolism gene	MRPL52	PSME1	0.833768524	9.60E-33
UCS	Cell metabolism gene	MRPL52	UROD	0.835860231	4.80E-33
UCS	Cell metabolism gene	MRPL52	FPGS	0.836110995	4.41E-33
UCS	Cell metabolism gene	MRPL52	GSTZ1	0.837375712	2.88E-33
UCS	Cell metabolism gene	MRPL52	SNRPD1	0.838932352	1.70E-33
UCS	Cell metabolism gene	MRPL52	COX17	0.839583174	1.36E-33
UCS	Cell metabolism gene	MRPL52	TAZ	0.839681037	1.32E-33
UCS	Cell metabolism gene	MRPL52	TXN	0.841534041	6.95E-34
UCS	Cell metabolism gene	MRPL52	SEC61B	0.842050403	5.81E-34
UCS	Cell metabolism gene	MRPL52	SSR2	0.844424201	2.52E-34
UCS	Cell metabolism gene	MRPL52	TSTA3	0.845366945	1.80E-34
UCS	Cell metabolism gene	MRPL52	PFDN5	0.84655482	1.18E-34
UCS	Cell metabolism gene	MRPL52	PSMB2	0.84772568	7.72E-35
UCS	Cell metabolism gene	MRPL52	TOMM22	0.847772467	7.59E-35
UCS	Cell metabolism gene	MRPL52	HMBS	0.84894935	4.94E-35
UCS	Cell metabolism gene	MRPL52	EXOSC5	0.851128856	2.21E-35
UCS	Cell metabolism gene	MRPL52	LSM5	0.851940164	1.64E-35
UCS	Cell metabolism gene	MRPL52	UROS	0.851948059	1.63E-35
UCS	Cell metabolism gene	MRPL52	PSMD8	0.855029988	5.08E-36
UCS	Cell metabolism gene	MRPL52	PSMA4	0.855651702	4.00E-36
UCS	Cell metabolism gene	MRPL52	MED27	0.855754791	3.85E-36
UCS	Cell metabolism gene	MRPL52	SNRPD3	0.856093464	3.38E-36
UCS	Cell metabolism gene	MRPL52	PSMC5	0.856174975	3.27E-36
UCS	Cell metabolism gene	MRPL52	GMPPA	0.856189944	3.25E-36
UCS	Cell metabolism gene	MRPL52	HMOX2	0.856915221	2.46E-36
UCS	Cell metabolism gene	MRPL52	DGAT1	0.857451259	1.99E-36
UCS	Cell metabolism gene	MRPL52	DHRS4	0.85820696	1.48E-36
UCS	Cell metabolism gene	MRPL52	MIF	0.858446726	1.35E-36
UCS	Cell metabolism gene	MRPL52	IDH3G	0.858492996	1.33E-36
UCS	Cell metabolism gene	MRPL52	POLR2F	0.858870041	1.14E-36
UCS	Cell metabolism gene	MRPL52	GSS	0.858924545	1.12E-36
UCS	Cell metabolism gene	MRPL52	OAZ1	0.860723537	5.48E-37
UCS	Cell metabolism gene	MRPL52	GALK1	0.864122991	1.38E-37
UCS	Cell metabolism gene	MRPL52	DHRS4L2	0.864333344	1.27E-37
UCS	Cell metabolism gene	MRPL52	FAU	0.865933334	6.54E-38
UCS	Cell metabolism gene	MRPL52	ATP5G1	0.866249755	5.73E-38
UCS	Cell metabolism gene	MRPL52	LSM2	0.86716203	3.91E-38
UCS	Cell metabolism gene	MRPL52	GEMIN6	0.867335111	3.64E-38
UCS	Cell metabolism gene	MRPL52	SNRPE	0.867495	3.40E-38
UCS	Cell metabolism gene	MRPL52	PMPCA	0.869109361	1.71E-38
UCS	Cell metabolism gene	MRPL52	PSMB4	0.869785985	1.28E-38
UCS	Cell metabolism gene	MRPL52	PSMB1	0.869998118	1.17E-38
UCS	Cell metabolism gene	MRPL52	MVD	0.870735057	8.51E-39
UCS	Cell metabolism gene	MRPL52	LSM3	0.8726857	3.63E-39
UCS	Cell metabolism gene	MRPL52	TBCB	0.873019442	3.13E-39
UCS	Cell metabolism gene	MRPL52	SNRPB	0.87323029	2.86E-39
UCS	Cell metabolism gene	MRPL52	DTYMK	0.876237569	7.42E-40
UCS	Cell metabolism gene	MRPL52	PAFAH1B3	0.878533219	2.59E-40
UCS	Cell metabolism gene	MRPL52	POLD2	0.880236655	1.17E-40
UCS	Cell metabolism gene	MRPL52	NANS	0.881530795	6.34E-41
UCS	Cell metabolism gene	MRPL52	ITPA	0.882326816	4.34E-41
UCS	Cell metabolism gene	MRPL52	DGUOK	0.882573868	3.85E-41
UCS	Cell metabolism gene	MRPL52	PSMB10	0.885845662	7.82E-42
UCS	Cell metabolism gene	MRPL52	PSMB6	0.888450286	2.12E-42
UCS	Cell metabolism gene	MRPL52	DPM2	0.888486727	2.08E-42
UCS	Cell metabolism gene	MRPL52	TIMM10	0.891727331	3.92E-43
UCS	Cell metabolism gene	MRPL52	SLC27A5	0.895808222	4.43E-44
UCS	Cell metabolism gene	MRPL52	PSME2	0.897302066	1.95E-44
UCS	Cell metabolism gene	MRPL52	GEMIN7	0.899130537	7.01E-45
UCS	Cell metabolism gene	MRPL52	MTX1	0.900402997	3.40E-45
UCS	Cell metabolism gene	MRPL52	SEC61G	0.903778765	4.76E-46
UCS	Cell metabolism gene	MRPL52	PGP	0.904505361	3.09E-46
UCS	Cell metabolism gene	MRPL52	PSMD13	0.90507198	2.20E-46
UCS	Cell metabolism gene	MRPL52	HSD17B10	0.905297862	1.92E-46
UCS	Cell metabolism gene	MRPL52	PGLS	0.906002396	1.25E-46
UCS	Cell metabolism gene	MRPL52	PHKG2	0.91044749	7.84E-48
UCS	Cell metabolism gene	MRPL52	LSM4	0.91132145	4.47E-48
UCS	Cell metabolism gene	MRPL52	WBSCR22	0.911388219	4.28E-48
UCS	Cell metabolism gene	MRPL52	DPM3	0.912304651	2.36E-48
UCS	Cell metabolism gene	MRPL52	EXOSC4	0.915725896	2.40E-49
UCS	Cell metabolism gene	MRPL52	TOMM40	0.91745773	7.28E-50
UCS	Cell metabolism gene	MRPL52	POLR2I	0.918928093	2.59E-50
UCS	Cell metabolism gene	MRPL52	PSMC3	0.920622276	7.68E-51
UCS	Cell metabolism gene	MRPL52	TIMM17B	0.92100754	5.80E-51
UCS	Cell metabolism gene	MRPL52	EBP	0.924380442	4.68E-52
UCS	Cell metabolism gene	MRPL52	PSMC1	0.925908511	1.44E-52
UCS	Cell metabolism gene	MRPL52	APRT	0.927343135	4.65E-53
UCS	Cell metabolism gene	MRPL52	PSMD4	0.928666571	1.61E-53
UCS	Cell metabolism gene	MRPL52	GUK1	0.930778132	2.82E-54
UCS	Cell metabolism gene	MRPL52	POLR2J	0.930978299	2.39E-54
UCS	Cell metabolism gene	MRPL52	POLR2H	0.931520725	1.51E-54
UCS	Cell metabolism gene	MRPL52	TIMM8B	0.936119134	2.68E-56
UCS	Cell metabolism gene	MRPL52	TIMM13	0.94056889	4.02E-58
UCS	Cell metabolism gene	MRPL52	PSMB7	0.946931639	5.44E-61
UCS	Cell metabolism gene	MRPL52	SNRPD2	0.952874191	5.22E-64
UCS	Cell metabolism gene	MRPL52	TIMM50	0.953135951	3.77E-64
UCS	Cell metabolism gene	MRPL52	ACOT8	0.95588234	1.09E-65
UCS	Cell metabolism gene	MRPL52	PSMB3	0.956387296	5.55E-66
UCS	CGC	MRPL52	ATIC	0.804373147	6.60E-29
UCS	CGC	MRPL52	RECQL4	0.808377135	2.17E-29
UCS	CGC	MRPL52	MGMT	0.817220439	1.69E-30
UCS	CGC	MRPL52	ASPSCR1	0.823615276	2.44E-31
UCS	CGC	MRPL52	MAP2K2	0.829479429	3.87E-32
UCS	CGC	MRPL52	RBM10	0.863503338	1.78E-37
UCS	CGC	MRPL52	SDHAF2	0.887400191	3.60E-42
UCS	CGC	MRPL52	COX6C	0.895505472	5.22E-44
UCS	CGC	MRPL52	TFPT	0.926894477	6.64E-53
UCS	Epifactor	MRPL52	SS18L2	0.800398396	1.94E-28
UCS	Epifactor	MRPL52	ACTR5	0.804354947	6.63E-29
UCS	Epifactor	MRPL52	CXXC1	0.804653259	6.11E-29
UCS	Epifactor	MRPL52	PPM1G	0.815403603	2.88E-30
UCS	Epifactor	MRPL52	HMG20B	0.82093606	5.54E-31
UCS	Epifactor	MRPL52	EXOSC1	0.823547077	2.49E-31
UCS	Epifactor	MRPL52	NOC2L	0.831187133	2.23E-32
UCS	Epifactor	MRPL52	PRMT1	0.832463147	1.47E-32
UCS	Epifactor	MRPL52	HIST2H2AC	0.834918247	6.56E-33
UCS	Epifactor	MRPL52	EXOSC5	0.851128856	2.21E-35
UCS	Epifactor	MRPL52	MBD3	0.85174568	1.76E-35
UCS	Epifactor	MRPL52	CCDC101	0.857731058	1.79E-36
UCS	Epifactor	MRPL52	RRP8	0.866262349	5.70E-38
UCS	Epifactor	MRPL52	PAF1	0.870109912	1.12E-38
UCS	Epifactor	MRPL52	C17orf49	0.873538852	2.49E-39
UCS	Epifactor	MRPL52	FBL	0.873886758	2.13E-39
UCS	Epifactor	MRPL52	LAS1L	0.881329617	6.98E-41
UCS	Epifactor	MRPL52	ZGPAT	0.88320407	2.84E-41
UCS	Epifactor	MRPL52	INO80E	0.885443639	9.53E-42
UCS	Epifactor	MRPL52	CDK5	0.887775089	2.98E-42
UCS	Epifactor	MRPL52	RUVBL2	0.89735669	1.89E-44
UCS	Epifactor	MRPL52	PPP4C	0.90743827	5.20E-47
UCS	Epifactor	MRPL52	EXOSC4	0.915725896	2.40E-49
UCS	Epifactor	MRPL52	TAF10	0.923472264	9.33E-52
UCS	Epifactor	MRPL52	TFPT	0.926894477	6.64E-53
UCS	Epifactor	MRPL52	SIRT6	0.927005729	6.08E-53
UCS	Epifactor	MRPL52	ZNHIT1	0.943094729	3.20E-59
UCS	Epifactor	MRPL52	PRPF31	0.944454071	7.81E-60
UCS	Epifactor	MRPL52	BRMS1	0.950090763	1.50E-62
UCS	IUPHAR	MRPL52	SLC25A11	0.800003915	2.16E-28
UCS	IUPHAR	MRPL52	UCHL3	0.801021711	1.64E-28
UCS	IUPHAR	MRPL52	ECE2	0.805980911	4.23E-29
UCS	IUPHAR	MRPL52	FKBP1A	0.806045133	4.16E-29
UCS	IUPHAR	MRPL52	SMPD2	0.806872876	3.30E-29
UCS	IUPHAR	MRPL52	MPDU1	0.807315787	2.92E-29
UCS	IUPHAR	MRPL52	MMP24	0.814913924	3.33E-30
UCS	IUPHAR	MRPL52	ABCB8	0.819234735	9.26E-31
UCS	IUPHAR	MRPL52	DYRK4	0.821034336	5.38E-31
UCS	IUPHAR	MRPL52	MAP2K2	0.829479429	3.87E-32
UCS	IUPHAR	MRPL52	EGLN2	0.83170653	1.88E-32
UCS	IUPHAR	MRPL52	PRMT1	0.832463147	1.47E-32
UCS	IUPHAR	MRPL52	PTGES2	0.833061094	1.21E-32
UCS	IUPHAR	MRPL52	ADCK5	0.8389651	1.68E-33
UCS	IUPHAR	MRPL52	ATP6V0B	0.839751865	1.29E-33
UCS	IUPHAR	MRPL52	PSMB2	0.84772568	7.72E-35
UCS	IUPHAR	MRPL52	ATG4B	0.849541483	3.98E-35
UCS	IUPHAR	MRPL52	HMOX2	0.856915221	2.46E-36
UCS	IUPHAR	MRPL52	DGAT1	0.857451259	1.99E-36
UCS	IUPHAR	MRPL52	SLC39A3	0.860574119	5.82E-37
UCS	IUPHAR	MRPL52	PSMB1	0.869998118	1.17E-38
UCS	IUPHAR	MRPL52	MVD	0.870735057	8.51E-39
UCS	IUPHAR	MRPL52	PPIA	0.88378755	2.14E-41
UCS	IUPHAR	MRPL52	CDK5	0.887775089	2.98E-42
UCS	IUPHAR	MRPL52	PSMB6	0.888450286	2.12E-42
UCS	IUPHAR	MRPL52	SLC27A5	0.895808222	4.43E-44
UCS	IUPHAR	MRPL52	PHKG2	0.91044749	7.84E-48
UCS	IUPHAR	MRPL52	SIRT6	0.927005729	6.08E-53
UCS	Kinase	MRPL52	DYRK4	0.821034336	5.38E-31
UCS	Kinase	MRPL52	MAP2K2	0.829479429	3.87E-32
UCS	Kinase	MRPL52	ADCK5	0.8389651	1.68E-33
UCS	Kinase	MRPL52	FASTK	0.843290361	3.76E-34
UCS	Kinase	MRPL52	ADCK4	0.849407529	4.18E-35
UCS	Kinase	MRPL52	CDK5	0.887775089	2.98E-42
UCS	Kinase	MRPL52	PHKG2	0.91044749	7.84E-48
UCS	TF	MRPL52	PREB	0.800278781	2.00E-28
UCS	TF	MRPL52	AKAP8L	0.802733519	1.03E-28
UCS	TF	MRPL52	CXXC1	0.804653259	6.11E-29
UCS	TF	MRPL52	GTF3A	0.807513073	2.76E-29
UCS	TF	MRPL52	SNAPC2	0.810830942	1.08E-29
UCS	TF	MRPL52	MYPOP	0.813381372	5.20E-30
UCS	TF	MRPL52	ZNF511	0.814196165	4.10E-30
UCS	TF	MRPL52	THAP3	0.81939755	8.82E-31
UCS	TF	MRPL52	HMG20B	0.82093606	5.54E-31
UCS	TF	MRPL52	THAP8	0.827822278	6.55E-32
UCS	TF	MRPL52	THAP7	0.829618987	3.70E-32
UCS	TF	MRPL52	ZNF524	0.830978374	2.39E-32
UCS	TF	MRPL52	ZNF581	0.836292291	4.15E-33
UCS	TF	MRPL52	DNTTIP1	0.837396178	2.86E-33
UCS	TF	MRPL52	ZNF668	0.844799754	2.21E-34
UCS	TF	MRPL52	PIN1	0.84648233	1.21E-34
UCS	TF	MRPL52	ZNF32	0.846630061	1.15E-34
UCS	TF	MRPL52	THYN1	0.847030358	9.93E-35
UCS	TF	MRPL52	ETV2	0.849185584	4.53E-35
UCS	TF	MRPL52	MBD3	0.85174568	1.76E-35
UCS	TF	MRPL52	ZNF444	0.856267294	3.16E-36
UCS	TF	MRPL52	IRF3	0.859021519	1.08E-36
UCS	TF	MRPL52	ZNF428	0.866465121	5.24E-38
UCS	TF	MRPL52	GLI4	0.869605013	1.39E-38
UCS	TF	MRPL52	RBCK1	0.873683074	2.34E-39
UCS	TF	MRPL52	USF1	0.875051885	1.27E-39
UCS	TF	MRPL52	ZGPAT	0.88320407	2.84E-41
UCS	TF	MRPL52	ZNF688	0.89417128	1.07E-43
UCS	TF	MRPL52	ZNF787	0.897185298	2.08E-44
UCS	TF	MRPL52	DRAP1	0.907292386	5.69E-47
UCS	TSG	MRPL52	AIP	0.800991891	1.66E-28
UCS	TSG	MRPL52	GLTSCR2	0.80327541	8.91E-29
UCS	TSG	MRPL52	TUSC2	0.805430283	4.93E-29
UCS	TSG	MRPL52	HTRA2	0.815184751	3.08E-30
UCS	TSG	MRPL52	NME1	0.825166188	1.51E-31
UCS	TSG	MRPL52	GNB2L1	0.828956416	4.57E-32
UCS	TSG	MRPL52	PFN1	0.836317545	4.12E-33
UCS	TSG	MRPL52	STUB1	0.839323516	1.49E-33
UCS	TSG	MRPL52	MAD1L1	0.840499475	9.94E-34
UCS	TSG	MRPL52	ZNF668	0.844799754	2.21E-34
UCS	TSG	MRPL52	PIN1	0.84648233	1.21E-34
UCS	TSG	MRPL52	ST20	0.848927606	4.98E-35
UCS	TSG	MRPL52	GABARAP	0.849099708	4.68E-35
UCS	TSG	MRPL52	IRF3	0.859021519	1.08E-36
UCS	TSG	MRPL52	PARK7	0.860320607	6.44E-37
UCS	TSG	MRPL52	NPRL2	0.895929914	4.14E-44
UCS	TSG	MRPL52	TSSC4	0.906100194	1.18E-46
UCS	TSG	MRPL52	GADD45GIP1	0.921871563	3.08E-51
UCS	TSG	MRPL52	SIRT6	0.927005729	6.08E-53
UCS	TSG	MRPL52	BRMS1	0.950090763	1.50E-62
UVM	Cell metabolism gene	MRPL52	PSMB6	0.800047539	5.50E-19
UVM	Cell metabolism gene	MRPL52	MTX1	0.819738402	1.44E-20
UVM	Epifactor	MRPL52	ZNHIT1	0.801432806	4.32E-19
UVM	IUPHAR	MRPL52	PSMB6	0.800047539	5.50E-19
UVM	TSG	MRPL52	GADD45GIP1	0.834819239	6.47E-22

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
BRCA	MRPL52	MRPL32	-3.7979134181794	0.000134327661287861
KIRP	MRPL52	MRPL51	-1.32840656722761	0.000213860534131527
KIRC	MRPL52	MRPL55	-1.02163441832258	0.000291940846845375
LIHC	MRPL52	MRPL13	1.54402472107614	0.000655351190157038
LUSC	MRPL52	MRPL39	-3.50411737429004	0.000985010025625636
LUAD	MRPL52	MRPL32	-2.1966239418264	0.00121089428940613
COAD	MRPL52	MRPL41	-2.99561502382389	0.00144392251968384
CHOL	MRPL52	MRPL41	-4.96379377542225	0.00390625
BLCA	MRPL52	MRPL39	1.69896851960452	0.00391769409179688
LUAD	MRPL52	MRPL39	-1.1049452981592	0.00471395891927286
THCA	MRPL52	MRPL41	-3.88188543554269	0.00492925389458784
ESCA	MRPL52	MRPL13	-1.07746088474995	0.0068359375
PRAD	MRPL52	ICT1	-1.54848444909352	0.00907723161841939
KIRP	MRPL52	MRPL38	1.28078686740376	0.0105091729201376
COAD	MRPL52	MRPL51	-1.84147877110728	0.0110453069210053
STAD	MRPL52	MRPL4	1.4393539135682	0.0279771662317216
COAD	MRPL52	MRPL39	-1.15285953291756	0.0357243716716767
KIRC	MRPL52	MRPL32	-2.79664327578899	0.0376051795400881
KIRP	MRPL52	MRPL49	-2.36524030474784	1.53668224811554e-08
LUAD	MRPL52	MRPL38	-1.82500284003406	2.20741561246108e-05
LIHC	MRPL52	MRPL32	-1.20074144698753	2.24402029682138e-06
BRCA	MRPL52	ICT1	-4.17488220449664	2.73719348917167e-14
COAD	MRPL52	MRPL4	2.77705897514473	2.98023223876954e-07
LUSC	MRPL52	MRPL38	-1.46267889332591	3.90393047420304e-06
LIHC	MRPL52	MRPL39	-1.65461683386216	3.95799979560965e-08
PRAD	MRPL52	MRPL41	1.31179686307216	4.41809300064344e-05
THCA	MRPL52	MRPL49	-1.28871899028168	5.42468304941934e-06
BRCA	MRPL52	MRPL51	-2.91631474502369	5.42627121034746e-18
BRCA	MRPL52	MRPL55	-1.64092910603924	6.01408870059924e-14
LUSC	MRPL52	ICT1	-3.23093376049456	6.60526357089358e-07
LUSC	MRPL52	MRPL55	-1.42665529836846	7.19742900589893e-05
LUAD	MRPL52	MRPL55	-2.50406829694459	7.3663238952828e-06
KICH	MRPL52	MRPL41	1.05103651319563	7.49826431274414e-05
KIRC	MRPL52	MRPL51	-1.59773648669469	8.46797387064351e-07
LUAD	MRPL52	MRPL51	-1.44585271087263	9.92276876427582e-07

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with MRPL52

APP, MRPL51, MRPL41, MRPL55, MRPL23, MRPL32, MRPL12, MRPL13, MRPL40, MRPL3, MRPL39, MRPL38, MRPL49, TMEM177, HNRNPU, TSR1, ICT1, DDX28, RPS18, CUL7, ERLEC1, NPM1, RPS2, MRPL4, HNRNPA1, MRPS30, KIF2C, MRPL50, MRPL9, MRPL1, Cul1, Pcgf1, FGF8, RRS1, LUC7L, ZNF2, RBM3, PRKCZ, LARP7, RC3H1, RC3H2, ALYREF, FBXW8, OBSL1, ZC3HAV1, ACAD9, C12orf65, C1QBP, C21orf33, C6orf203, CS, FASTKD2, GFM1, GFM2, GRSF1, HINT2, LRPPRC, MDH2, METTL17, MRPL11, MRPS12, MRPS26, MRRF, MTERF3, MTG1, MTG2, MTIF3, MTRF1L, NGRN, PMPCA, PMPCB, SLIRP, SSBP1, TACO1, TBRG4, TMEM70, TRUB2, TSFM, TUFM, EXD2, H2AFB3, H2AFB2, S100P, YBX1, MRPL44, MRPL20, MRPL2, RPS9, H1FNT, NEIL1, SRSF3, RPL26L1, RPS3A, MRPL57, RPL4, MRPL18, MRPL47, MRPL17, MRPL42, RBMS2, YARS2, PABPC5, MRPL30, RPS6, MRPL22, MRPL24, GADD45GIP1, MRPL27, RPL13, MRPL35, SRSF5, MRPL15, GLI4, MRPL34, MRPL28, MRPL16, MRPL45, ZNF346, MALSU1, MRPL10, ZNF574, PTCD1, SRSF7, MRPL19, MRPL37, C17orf85, RPL13A, ZC3H3, RPL23A, RPL19, CBX6, PRR3, SRSF6, MRPL21, MRPL48, MRPL46, RPL35, MRPS18A, RPL17, MRPL43, CREB1, RPL36AL, PDCD11, HIST1H1A, RPS8, ABT1, OXA1L, RPL7A, BCKDK, MRPL53, PAK3, RPL3, RPL10,

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Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
MRPL52	BRCA	chr14	23299300	23299300	G	A	Missense_Mutation	p.G24S	3
MRPL52	BRCA	chr14	23302667	23302667	A	G	Silent	p.R66	3
MRPL52	UCEC	chr14	23303404	23303404	G	T	Nonsense_Mutation	p.G61*	2
MRPL52	HNSC	chr14	23299461	23299461	C	T	Missense_Mutation	p.A52V	2
MRPL52	LIHC	chr14	23303475	23303475	A	-	Frame_Shift_Del	p.E106fs	2
MRPL52	BLCA	chr14	23303385	23303385	G	A	Missense_Mutation		2
MRPL52	BLCA	chr14	23299420	23299420	C	T	Silent	p.S38S	2
MRPL52	BLCA	chr14	23303385	23303385	G	A	Missense_Mutation	p.R76Q	2
MRPL52	SKCM	chr14	23299432	23299432	C	T	Silent	p.P42P	2
MRPL52	COAD	chr14	23299135	23299135	G	T	Missense_Mutation	p.G5V	1
MRPL52	HNSC	chr14	23299408	23299409	-	G	Frame_Shift_Ins	p.A34fs	1
MRPL52	LIHC	chr14	23302670	23302670	A	G	Silent		1
MRPL52	LIHC	chr14	23302670	23302670	A	G	Silent	p.K67K	1
MRPL52	BLCA	chr14	23299420	23299420	C	T	Silent		1
MRPL52	LIHC	chr14	23303489	23303489	C	-	Frame_Shift_Del	p.P111fs	1
MRPL52	SARC	chr14	23299135	23299135	G	T	Missense_Mutation		1
MRPL52	SARC	chr14	23302658	23302658	G	T	Missense_Mutation		1

Copy number variation (CNV) of MRPL52
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across MRPL52
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
95423	KICH	TCGA-KO-8404-01A	ARNT	chr1	150818739	-	MRPL52	chr14	23303381	+
95423	OV	TCGA-24-2019	CHMP4A	chr14	24682614	-	MRPL52	chr14	23303380	+
95423	N/A	CK826457	FAM96A	chr15	64366473	+	MRPL52	chr14	23299118	+
55104	SKCM	TCGA-EE-A29V-06A	MRPL52	chr14	23299463	+	C14orf93	chr14	23468365	-
82388	N/A	BF344387	MRPL52	chr14	23303556	+	C20orf196	chr20	5792752	-
85485	N/A	AA933040	MRPL52	chr14	23302656	-	CTSD	chr11	1778597	+
95423	N/A	BF509847	MRPL52	chr14	23301188	-	MRPL52	chr14	23301576	-
88952	N/A	DL058935	MRPL52	chr14	23300316	-	PTBP3	chr9	115006570	+
59695	LIHC	TCGA-BC-A10Z-01A	MRPL52	chr14	23302691	+	TSKS	chr19	50265489	-
95423	ESCA	TCGA-IG-A6QS	SAMHD1	chr20	35559162	-	MRPL52	chr14	23303380	+
95425	STAD	TCGA-HU-A4GN-01A	TUBGCP6	chr22	50678633	-	MRPL52	chr14	23303381	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRP	MRPL52	5.1794728725741e-05	0.0015

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUSC	MRPL52	0.000820311468139752	0.027
KIRP	MRPL52	0.0403560815623675	1
THYM	MRPL52	0.0281313233471276	0.87
SARC	MRPL52	0.0169659234223069	0.54

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source