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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: MRPL55 (NCBI Gene ID:128308)

Gene Summary

Gene Summary

Gene Information	Gene Name: MRPL55
	Gene ID: 128308
	Gene Symbol	MRPL55
	Gene ID	128308
	Gene Name	mitochondrial ribosomal protein L55
	Synonyms	AAVG5835\|L55nt\|MRP-L55\|PRO19675
	Cytomap	1q42.13
	Type of Gene	protein-coding
	Description	39S ribosomal protein L55, mitochondrialL55mtmitochondrial large ribosomal subunit protein bL31mmitochondrial large ribosomal subunit protein mL55
	Modification date	20200313
	UniProtAcc	Q7Z7F7

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene

Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25

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Translation Studies in PubMed

We searched PubMed using 'MRPL55[title] AND translation [title] AND human.'

Gene	Title	PMID
MRPL55	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000295008	228295368	228295570	Frame-shift
ENST00000336300	228295368	228295570	Frame-shift
ENST00000336520	228295368	228295570	Frame-shift
ENST00000348259	228295368	228295570	Frame-shift
ENST00000366733	228295368	228295570	Frame-shift
ENST00000366734	228295368	228295570	Frame-shift
ENST00000366735	228295368	228295570	Frame-shift
ENST00000366736	228295368	228295570	Frame-shift
ENST00000366739	228295368	228295570	Frame-shift
ENST00000366740	228295368	228295570	Frame-shift
ENST00000366741	228295368	228295570	Frame-shift
ENST00000366742	228295368	228295570	Frame-shift
ENST00000366744	228295368	228295570	Frame-shift
ENST00000366746	228295368	228295570	Frame-shift
ENST00000366747	228295368	228295570	Frame-shift
ENST00000391867	228295368	228295570	Frame-shift
ENST00000295008	228295935	228296019	3UTR-3CDS
ENST00000336520	228295935	228296019	3UTR-3CDS
ENST00000348259	228295935	228296019	3UTR-3CDS
ENST00000366741	228295935	228296019	3UTR-3CDS
ENST00000366742	228295935	228296022	3UTR-3CDS
ENST00000366746	228295935	228296019	3UTR-3CDS
ENST00000336300	228296137	228296175	3UTR-3UTR
ENST00000366736	228296137	228296209	3UTR-3UTR
ENST00000366739	228296137	228296175	3UTR-3UTR
ENST00000366740	228296137	228296175	3UTR-3UTR
ENST00000366747	228296137	228296175	3UTR-3UTR
ENST00000391867	228296137	228296175	3UTR-3UTR
ENST00000366744	228296141	228296209	3UTR-3UTR
ENST00000295008	228296655	228296722	3UTR-3UTR
ENST00000336520	228296655	228296722	3UTR-3UTR
ENST00000391867	228296655	228296722	3UTR-3UTR

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
KIRC	MRPL55	-1.02163441832258	0.000291940846845375
BRCA	MRPL55	-1.64092910603924	6.01408870059924e-14
LUSC	MRPL55	-1.42665529836846	7.19742900589893e-05
LUAD	MRPL55	-2.50406829694459	7.3663238952828e-06

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
LAML	MRPL55	2	3	0.0288538917711787	0.498339329608939	0.619717333333333	-0.290377720329571	-0.578892506177093
LGG	MRPL55	2	3	0.0410439566408453	0.523253579881657	0.612235454545455	-0.738718068306107	-0.981798263750945
SARC	MRPL55	2	1	0.0337446174116997	0.307500678294574	0.173048295454545	0.0804871837458341	0.602742645338509

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
CESC	MRPL55	3	2	0.00967751388645459	0.61028275862069	0.531022311963655	-0.138231191356918	0.173982967288136
HNSC	MRPL55	3	2	0.0445511573663847	0.606950420168067	0.536541258563816	0.465519924261765	0.26094541794056

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
SARC	MRPL55	0.109464537	0.025726238
BLCA	MRPL55	0.052219924	0.040301282

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with MRPL55 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
BRCA	Cell metabolism gene	MRPL55	MTX1	0.801280881	1.51E-273
BRCA	Cell metabolism gene	MRPL55	GUK1	0.853193551	0
CESC	Cell metabolism gene	MRPL55	MTX1	0.822048458	8.04E-77
DLBC	Cell metabolism gene	MRPL55	PTDSS2	0.800051967	8.97E-12
DLBC	Cell metabolism gene	MRPL55	PIGQ	0.80043272	8.62E-12
DLBC	Cell metabolism gene	MRPL55	POLR2J	0.800566889	8.50E-12
DLBC	Cell metabolism gene	MRPL55	TIMM8B	0.803405548	6.32E-12
DLBC	Cell metabolism gene	MRPL55	ECHS1	0.803824824	6.05E-12
DLBC	Cell metabolism gene	MRPL55	SNRPD2	0.804354254	5.72E-12
DLBC	Cell metabolism gene	MRPL55	PGLS	0.805231875	5.21E-12
DLBC	Cell metabolism gene	MRPL55	LYPLA2	0.805510998	5.06E-12
DLBC	Cell metabolism gene	MRPL55	POLR2F	0.805542637	5.04E-12
DLBC	Cell metabolism gene	MRPL55	SAT2	0.805591763	5.01E-12
DLBC	Cell metabolism gene	MRPL55	GEMIN7	0.806789336	4.41E-12
DLBC	Cell metabolism gene	MRPL55	ITPA	0.807633917	4.03E-12
DLBC	Cell metabolism gene	MRPL55	PSMC1	0.807662791	4.01E-12
DLBC	Cell metabolism gene	MRPL55	ACOT8	0.809649222	3.23E-12
DLBC	Cell metabolism gene	MRPL55	DPM2	0.817986445	1.27E-12
DLBC	Cell metabolism gene	MRPL55	PSMC3	0.819365012	1.08E-12
DLBC	Cell metabolism gene	MRPL55	TOMM22	0.819510488	1.07E-12
DLBC	Cell metabolism gene	MRPL55	PSMC5	0.820131964	9.92E-13
DLBC	Cell metabolism gene	MRPL55	TIMM9	0.82155562	8.40E-13
DLBC	Cell metabolism gene	MRPL55	LSM4	0.822187655	7.79E-13
DLBC	Cell metabolism gene	MRPL55	DPM3	0.822344294	7.65E-13
DLBC	Cell metabolism gene	MRPL55	PSMD4	0.827430978	4.16E-13
DLBC	Cell metabolism gene	MRPL55	PHKG2	0.828218821	3.78E-13
DLBC	Cell metabolism gene	MRPL55	MIF	0.833513629	1.95E-13
DLBC	Cell metabolism gene	MRPL55	PSMD13	0.833787529	1.89E-13
DLBC	Cell metabolism gene	MRPL55	MTX1	0.834775962	1.66E-13
DLBC	Cell metabolism gene	MRPL55	FAU	0.835331837	1.55E-13
DLBC	Cell metabolism gene	MRPL55	POLE4	0.835749314	1.47E-13
DLBC	Cell metabolism gene	MRPL55	NME2	0.836104402	1.40E-13
DLBC	Cell metabolism gene	MRPL55	TSTA3	0.836942543	1.26E-13
DLBC	Cell metabolism gene	MRPL55	PFDN5	0.839831563	8.62E-14
DLBC	Cell metabolism gene	MRPL55	POLR2L	0.840956268	7.42E-14
DLBC	Cell metabolism gene	MRPL55	UROD	0.841688684	6.73E-14
DLBC	Cell metabolism gene	MRPL55	TIMM13	0.844078364	4.88E-14
DLBC	Cell metabolism gene	MRPL55	POLR2I	0.844116538	4.85E-14
DLBC	Cell metabolism gene	MRPL55	EXOSC4	0.863657195	2.78E-15
DLBC	Cell metabolism gene	MRPL55	PSMB6	0.872537377	6.52E-16
DLBC	Cell metabolism gene	MRPL55	PSMB3	0.878284091	2.41E-16
DLBC	Cell metabolism gene	MRPL55	GUK1	0.890280327	2.53E-17
DLBC	Cell metabolism gene	MRPL55	GFER	0.895423945	8.87E-18
DLBC	CGC	MRPL55	TFPT	0.807530311	4.07E-12
DLBC	CGC	MRPL55	HRAS	0.837111919	1.23E-13
DLBC	CGC	MRPL55	NTHL1	0.842647997	5.92E-14
DLBC	Epifactor	MRPL55	PPP4C	0.801582786	7.65E-12
DLBC	Epifactor	MRPL55	TFPT	0.807530311	4.07E-12
DLBC	Epifactor	MRPL55	INO80E	0.820889308	9.08E-13
DLBC	Epifactor	MRPL55	SIRT6	0.821471958	8.48E-13
DLBC	Epifactor	MRPL55	BRMS1	0.82422271	6.12E-13
DLBC	Epifactor	MRPL55	DMAP1	0.83160285	2.48E-13
DLBC	Epifactor	MRPL55	MBD3	0.833620152	1.93E-13
DLBC	Epifactor	MRPL55	RBX1	0.856320489	8.54E-15
DLBC	Epifactor	MRPL55	ZNHIT1	0.856760791	8.00E-15
DLBC	Epifactor	MRPL55	EXOSC4	0.863657195	2.78E-15
DLBC	IUPHAR	MRPL55	ATG4B	0.815731309	1.64E-12
DLBC	IUPHAR	MRPL55	MPDU1	0.818331846	1.22E-12
DLBC	IUPHAR	MRPL55	SIRT6	0.821471958	8.48E-13
DLBC	IUPHAR	MRPL55	PHKG2	0.828218821	3.78E-13
DLBC	IUPHAR	MRPL55	HRAS	0.837111919	1.23E-13
DLBC	IUPHAR	MRPL55	PSMB6	0.872537377	6.52E-16
DLBC	Kinase	MRPL55	PHKG2	0.828218821	3.78E-13
DLBC	TF	MRPL55	ZNF444	0.810639732	2.90E-12
DLBC	TF	MRPL55	MBD3	0.833620152	1.93E-13
DLBC	TF	MRPL55	THAP3	0.835945067	1.43E-13
DLBC	TF	MRPL55	NME2	0.836104402	1.40E-13
DLBC	TF	MRPL55	THAP4	0.865689146	2.01E-15
DLBC	TF	MRPL55	THAP7	0.882985734	1.02E-16
DLBC	TSG	MRPL55	PARK7	0.809950282	3.13E-12
DLBC	TSG	MRPL55	SIRT6	0.821471958	8.48E-13
DLBC	TSG	MRPL55	BRMS1	0.82422271	6.12E-13
DLBC	TSG	MRPL55	STUB1	0.832109148	2.33E-13
DLBC	TSG	MRPL55	TSSC4	0.892407395	1.65E-17
DLBC	TSG	MRPL55	GADD45GIP1	0.909603096	3.64E-19
HNSC	Cell metabolism gene	MRPL55	PSMB4	0.813906155	4.06E-135
HNSC	Cell metabolism gene	MRPL55	MTX1	0.823927415	3.16E-141
HNSC	Cell metabolism gene	MRPL55	PSMD4	0.855670551	1.77E-163
KICH	Cell metabolism gene	MRPL55	PFDN2	0.80699523	4.56E-22
KICH	Cell metabolism gene	MRPL55	PSMB4	0.81833693	4.01E-23
KICH	Cell metabolism gene	MRPL55	PSMB3	0.818936358	3.51E-23
KICH	Cell metabolism gene	MRPL55	MTX1	0.825161242	8.56E-24
KICH	CGC	MRPL55	ASPSCR1	0.841596545	1.55E-25
KICH	Epifactor	MRPL55	DMAP1	0.811608181	1.73E-22
KIRP	Cell metabolism gene	MRPL55	POLR2I	0.814480894	6.97E-78
KIRP	Cell metabolism gene	MRPL55	MTX1	0.821981415	1.78E-80
KIRP	Cell metabolism gene	MRPL55	PSMD4	0.824454206	2.33E-81
KIRP	Cell metabolism gene	MRPL55	PSMB4	0.841458531	8.02E-88
KIRP	CGC	MRPL55	ASPSCR1	0.80618489	3.78E-75
KIRP	TSG	MRPL55	GADD45GIP1	0.829090518	4.75E-83
LAML	Cell metabolism gene	MRPL55	IDH3B	0.819752456	3.00E-43
LAML	Cell metabolism gene	MRPL55	GUK1	0.836586734	1.48E-46
LAML	Epifactor	MRPL55	MCRS1	0.811600116	9.08E-42
LAML	Epifactor	MRPL55	PRPF31	0.817987879	6.37E-43
LAML	TSG	MRPL55	STUB1	0.815407525	1.89E-42
MESO	Cell metabolism gene	MRPL55	GUK1	0.828852867	3.77E-23
PAAD	Epifactor	MRPL55	ZNHIT1	0.827512284	3.01E-47
PAAD	TSG	MRPL55	TSSC4	0.803075897	1.48E-42
PCPG	Cell metabolism gene	MRPL55	DPM3	0.812395427	3.31E-45
PCPG	TSG	MRPL55	GADD45GIP1	0.804899546	8.54E-44
PRAD	Cell metabolism gene	MRPL55	MTX1	0.800212092	8.78E-124
PRAD	Cell metabolism gene	MRPL55	PSMC5	0.800260116	8.28E-124
PRAD	Cell metabolism gene	MRPL55	DPM2	0.801511697	1.79E-124
PRAD	Cell metabolism gene	MRPL55	PSMC3	0.804422754	4.83E-126
PRAD	Cell metabolism gene	MRPL55	LSM4	0.808665543	2.25E-128
PRAD	Cell metabolism gene	MRPL55	IDH3G	0.809609824	6.68E-129
PRAD	Cell metabolism gene	MRPL55	PSMB4	0.811450383	6.15E-130
PRAD	Cell metabolism gene	MRPL55	PGLS	0.811585545	5.15E-130
PRAD	Cell metabolism gene	MRPL55	HSD17B10	0.811708931	4.39E-130
PRAD	Cell metabolism gene	MRPL55	TIMM50	0.812042978	2.84E-130
PRAD	Cell metabolism gene	MRPL55	FAU	0.812378173	1.83E-130
PRAD	Cell metabolism gene	MRPL55	PHPT1	0.815514341	2.89E-132
PRAD	Cell metabolism gene	MRPL55	OAZ1	0.816934203	4.30E-133
PRAD	Cell metabolism gene	MRPL55	GPX1	0.817616262	1.71E-133
PRAD	Cell metabolism gene	MRPL55	GFER	0.819605139	1.14E-134
PRAD	Cell metabolism gene	MRPL55	NME3	0.819613169	1.13E-134
PRAD	Cell metabolism gene	MRPL55	POLR2F	0.820147634	5.42E-135
PRAD	Cell metabolism gene	MRPL55	GPX4	0.826732188	5.28E-139
PRAD	Cell metabolism gene	MRPL55	B4GALT7	0.828303536	5.49E-140
PRAD	Cell metabolism gene	MRPL55	TIMM17B	0.831631129	4.22E-142
PRAD	Cell metabolism gene	MRPL55	POLR2L	0.832546166	1.09E-142
PRAD	Cell metabolism gene	MRPL55	PSMD4	0.832916402	6.26E-143
PRAD	Cell metabolism gene	MRPL55	PSMB3	0.857218182	4.44E-160
PRAD	Cell metabolism gene	MRPL55	POLR2I	0.871679688	7.18E-172
PRAD	Cell metabolism gene	MRPL55	DPM3	0.884467346	1.47E-183
PRAD	Cell metabolism gene	MRPL55	GUK1	0.898428549	5.18E-198
PRAD	CGC	MRPL55	MAP2K2	0.814629054	9.38E-132
PRAD	CGC	MRPL55	ASPSCR1	0.839681645	2.05E-147
PRAD	CGC	MRPL55	HRAS	0.843404951	5.69E-150
PRAD	Epifactor	MRPL55	INO80E	0.801315448	2.27E-124
PRAD	Epifactor	MRPL55	DMAP1	0.80347378	1.58E-125
PRAD	Epifactor	MRPL55	PRPF31	0.815733032	2.15E-132
PRAD	Epifactor	MRPL55	TAF10	0.82373513	3.71E-137
PRAD	Epifactor	MRPL55	SIRT6	0.838521648	1.25E-146
PRAD	Epifactor	MRPL55	BRMS1	0.84015539	9.80E-148
PRAD	Epifactor	MRPL55	ZNHIT1	0.884243394	2.42E-183
PRAD	IUPHAR	MRPL55	CSNK2B	0.803519806	1.49E-125
PRAD	IUPHAR	MRPL55	MAP2K2	0.814629054	9.38E-132
PRAD	IUPHAR	MRPL55	SIRT6	0.838521648	1.25E-146
PRAD	IUPHAR	MRPL55	HRAS	0.843404951	5.69E-150
PRAD	Kinase	MRPL55	MAP2K2	0.814629054	9.38E-132
PRAD	Kinase	MRPL55	FASTK	0.839128164	4.87E-147
PRAD	TF	MRPL55	DRAP1	0.806169871	5.38E-127
PRAD	TF	MRPL55	ZNF524	0.806253667	4.84E-127
PRAD	TF	MRPL55	ZNF444	0.811903555	3.40E-130
PRAD	TF	MRPL55	ZNF688	0.826111885	1.28E-138
PRAD	TF	MRPL55	THAP3	0.834206698	9.06E-144
PRAD	TF	MRPL55	THAP7	0.84700698	1.65E-152
PRAD	TSG	MRPL55	STUB1	0.829759814	6.61E-141
PRAD	TSG	MRPL55	SIRT6	0.838521648	1.25E-146
PRAD	TSG	MRPL55	BRMS1	0.84015539	9.80E-148
PRAD	TSG	MRPL55	TSSC4	0.843928495	2.46E-150
PRAD	TSG	MRPL55	GADD45GIP1	0.894762919	5.07E-194
READ	Cell metabolism gene	MRPL55	GUK1	0.80121298	1.04E-24
READ	Cell metabolism gene	MRPL55	PSMB4	0.803789762	5.70E-25
READ	Cell metabolism gene	MRPL55	POLR2I	0.812831282	6.42E-26
READ	Cell metabolism gene	MRPL55	MTX1	0.840188222	3.93E-29
READ	TSG	MRPL55	GADD45GIP1	0.825799028	2.26E-27
SKCM	Cell metabolism gene	MRPL55	GUK1	0.801238508	2.41E-107
TGCT	Cell metabolism gene	MRPL55	MTX1	0.816397633	1.49E-38
THCA	Cell metabolism gene	MRPL55	IDH3G	0.801709062	1.66E-129
THCA	Cell metabolism gene	MRPL55	PSMD13	0.801999037	1.15E-129
THCA	Cell metabolism gene	MRPL55	LSM4	0.805024937	2.29E-131
THCA	Cell metabolism gene	MRPL55	POLR2H	0.809924145	3.49E-134
THCA	Cell metabolism gene	MRPL55	PHKG2	0.811777423	2.85E-135
THCA	Cell metabolism gene	MRPL55	PFDN5	0.813047669	5.05E-136
THCA	Cell metabolism gene	MRPL55	POLR2L	0.8141316	1.14E-136
THCA	Cell metabolism gene	MRPL55	PSMD4	0.81422388	1.00E-136
THCA	Cell metabolism gene	MRPL55	TOMM40	0.816272338	5.86E-138
THCA	Cell metabolism gene	MRPL55	B4GALT7	0.821244938	5.10E-141
THCA	Cell metabolism gene	MRPL55	TIMM13	0.821803531	2.28E-141
THCA	Cell metabolism gene	MRPL55	PSMC3	0.822960032	4.26E-142
THCA	Cell metabolism gene	MRPL55	APRT	0.824446768	4.86E-143
THCA	Cell metabolism gene	MRPL55	SNRPD2	0.82625046	3.38E-144
THCA	Cell metabolism gene	MRPL55	PPCDC	0.826367456	2.84E-144
THCA	Cell metabolism gene	MRPL55	ACOT8	0.826799676	1.49E-144
THCA	Cell metabolism gene	MRPL55	PSMB6	0.82829353	1.59E-145
THCA	Cell metabolism gene	MRPL55	B3GAT3	0.830577134	5.00E-147
THCA	Cell metabolism gene	MRPL55	ITPA	0.831306106	1.64E-147
THCA	Cell metabolism gene	MRPL55	NME3	0.834115855	2.11E-149
THCA	Cell metabolism gene	MRPL55	PHPT1	0.835287954	3.34E-150
THCA	Cell metabolism gene	MRPL55	FAU	0.836049786	1.00E-150
THCA	Cell metabolism gene	MRPL55	GUK1	0.838318416	2.68E-152
THCA	Cell metabolism gene	MRPL55	PGLS	0.839729793	2.74E-153
THCA	Cell metabolism gene	MRPL55	PSMB4	0.841540461	1.42E-154
THCA	Cell metabolism gene	MRPL55	GAMT	0.844231177	1.63E-156
THCA	Cell metabolism gene	MRPL55	NT5C	0.844503316	1.03E-156
THCA	Cell metabolism gene	MRPL55	PSMC5	0.844743501	6.88E-157
THCA	Cell metabolism gene	MRPL55	POLR2J	0.852160693	1.87E-162
THCA	Cell metabolism gene	MRPL55	PSMB3	0.864318547	2.84E-172
THCA	Cell metabolism gene	MRPL55	MTX1	0.879514222	5.61E-186
THCA	Cell metabolism gene	MRPL55	POLR2I	0.890070462	1.22E-196
THCA	Cell metabolism gene	MRPL55	EXOSC4	0.897250434	1.56E-204
THCA	Cell metabolism gene	MRPL55	DPM3	0.916541916	4.99E-229
THCA	CGC	MRPL55	NTHL1	0.813210958	4.04E-136
THCA	CGC	MRPL55	TFPT	0.824600564	3.87E-143
THCA	CGC	MRPL55	HRAS	0.842386832	3.51E-155
THCA	CGC	MRPL55	ASPSCR1	0.881105868	1.61E-187
THCA	Epifactor	MRPL55	TAF10	0.803469648	1.73E-130
THCA	Epifactor	MRPL55	HMG20B	0.813319872	3.48E-136
THCA	Epifactor	MRPL55	DMAP1	0.818199982	3.91E-139
THCA	Epifactor	MRPL55	TFPT	0.824600564	3.87E-143
THCA	Epifactor	MRPL55	BRMS1	0.839633854	3.20E-153
THCA	Epifactor	MRPL55	INO80E	0.850493353	3.54E-161
THCA	Epifactor	MRPL55	PRPF31	0.85251163	1.00E-162
THCA	Epifactor	MRPL55	RUVBL2	0.889221005	9.67E-196
THCA	Epifactor	MRPL55	EXOSC4	0.897250434	1.56E-204
THCA	Epifactor	MRPL55	ZNHIT1	0.914135382	1.15E-225
THCA	IUPHAR	MRPL55	PHKG2	0.811777423	2.85E-135
THCA	IUPHAR	MRPL55	TPRA1	0.814794173	4.57E-137
THCA	IUPHAR	MRPL55	PSMB6	0.82829353	1.59E-145
THCA	IUPHAR	MRPL55	HRAS	0.842386832	3.51E-155
THCA	IUPHAR	MRPL55	NT5C	0.844503316	1.03E-156
THCA	Kinase	MRPL55	PHKG2	0.811777423	2.85E-135
THCA	Kinase	MRPL55	FASTK	0.844272601	1.52E-156
THCA	TF	MRPL55	ZNF428	0.800115136	1.27E-128
THCA	TF	MRPL55	ZNF787	0.805345048	1.51E-131
THCA	TF	MRPL55	HMG20B	0.813319872	3.48E-136
THCA	TF	MRPL55	ZNF688	0.836100153	9.26E-151
THCA	TF	MRPL55	THAP7	0.838997778	8.96E-153
THCA	TSG	MRPL55	AIP	0.817712723	7.78E-139
THCA	TSG	MRPL55	NPRL2	0.818070511	4.70E-139
THCA	TSG	MRPL55	TSSC4	0.837117001	1.84E-151
THCA	TSG	MRPL55	BRMS1	0.839633854	3.20E-153
THCA	TSG	MRPL55	GADD45GIP1	0.902058109	3.74E-210
THYM	Cell metabolism gene	MRPL55	PFDN2	0.801452914	1.46E-28
THYM	Cell metabolism gene	MRPL55	LCMT1	0.801841249	1.32E-28
THYM	Cell metabolism gene	MRPL55	COX17	0.802331795	1.15E-28
THYM	Cell metabolism gene	MRPL55	TOMM22	0.805667291	4.62E-29
THYM	Cell metabolism gene	MRPL55	DHRS4L2	0.806832293	3.34E-29
THYM	Cell metabolism gene	MRPL55	LSM4	0.807269077	2.96E-29
THYM	Cell metabolism gene	MRPL55	DGUOK	0.807340594	2.90E-29
THYM	Cell metabolism gene	MRPL55	GSTP1	0.807482968	2.79E-29
THYM	Cell metabolism gene	MRPL55	ALG3	0.80957079	1.55E-29
THYM	Cell metabolism gene	MRPL55	DHRS4	0.809962772	1.39E-29
THYM	Cell metabolism gene	MRPL55	SLC27A5	0.810634726	1.14E-29
THYM	Cell metabolism gene	MRPL55	DOHH	0.81115112	9.88E-30
THYM	Cell metabolism gene	MRPL55	PSMB10	0.812189223	7.34E-30
THYM	Cell metabolism gene	MRPL55	PFDN5	0.814812426	3.43E-30
THYM	Cell metabolism gene	MRPL55	DGAT1	0.818345363	1.21E-30
THYM	Cell metabolism gene	MRPL55	UROS	0.818627495	1.11E-30
THYM	Cell metabolism gene	MRPL55	HMBS	0.81874834	1.07E-30
THYM	Cell metabolism gene	MRPL55	IDH3G	0.819586828	8.33E-31
THYM	Cell metabolism gene	MRPL55	PSMB6	0.820394146	6.53E-31
THYM	Cell metabolism gene	MRPL55	PGP	0.8208634	5.66E-31
THYM	Cell metabolism gene	MRPL55	TSTA3	0.822706692	3.23E-31
THYM	Cell metabolism gene	MRPL55	TAZ	0.823983623	2.18E-31
THYM	Cell metabolism gene	MRPL55	CYC1	0.825743706	1.26E-31
THYM	Cell metabolism gene	MRPL55	SRM	0.825774118	1.25E-31
THYM	Cell metabolism gene	MRPL55	FAU	0.826252083	1.08E-31
THYM	Cell metabolism gene	MRPL55	PMPCA	0.826279759	1.07E-31
THYM	Cell metabolism gene	MRPL55	GEMIN6	0.830972116	2.39E-32
THYM	Cell metabolism gene	MRPL55	SSR4	0.831681794	1.90E-32
THYM	Cell metabolism gene	MRPL55	POLE4	0.836844268	3.45E-33
THYM	Cell metabolism gene	MRPL55	HMOX2	0.837736696	2.55E-33
THYM	Cell metabolism gene	MRPL55	POLR2F	0.842468052	5.02E-34
THYM	Cell metabolism gene	MRPL55	ITPA	0.842484793	4.99E-34
THYM	Cell metabolism gene	MRPL55	EXOSC5	0.843116711	4.00E-34
THYM	Cell metabolism gene	MRPL55	PSMB7	0.843497307	3.50E-34
THYM	Cell metabolism gene	MRPL55	TBCB	0.843808885	3.13E-34
THYM	Cell metabolism gene	MRPL55	PSMC5	0.843824218	3.12E-34
THYM	Cell metabolism gene	MRPL55	PTGES2	0.844702758	2.28E-34
THYM	Cell metabolism gene	MRPL55	PPCDC	0.845523889	1.71E-34
THYM	Cell metabolism gene	MRPL55	PMVK	0.848969622	4.91E-35
THYM	Cell metabolism gene	MRPL55	PHKG2	0.853941212	7.69E-36
THYM	Cell metabolism gene	MRPL55	PSMC1	0.854216597	6.93E-36
THYM	Cell metabolism gene	MRPL55	TIMM8B	0.855068368	5.01E-36
THYM	Cell metabolism gene	MRPL55	MED27	0.855099044	4.95E-36
THYM	Cell metabolism gene	MRPL55	GSTZ1	0.860615197	5.72E-37
THYM	Cell metabolism gene	MRPL55	GMPPA	0.862415845	2.77E-37
THYM	Cell metabolism gene	MRPL55	NANS	0.862816846	2.36E-37
THYM	Cell metabolism gene	MRPL55	EBP	0.863139139	2.07E-37
THYM	Cell metabolism gene	MRPL55	SNRPD2	0.863199335	2.02E-37
THYM	Cell metabolism gene	MRPL55	TIMM10	0.864616487	1.13E-37
THYM	Cell metabolism gene	MRPL55	DPM2	0.866310623	5.59E-38
THYM	Cell metabolism gene	MRPL55	TIMM13	0.867323101	3.66E-38
THYM	Cell metabolism gene	MRPL55	PSME2	0.86926791	1.60E-38
THYM	Cell metabolism gene	MRPL55	TOMM40	0.871656247	5.70E-39
THYM	Cell metabolism gene	MRPL55	GEMIN7	0.872226541	4.44E-39
THYM	Cell metabolism gene	MRPL55	TIMM17B	0.875187061	1.19E-39
THYM	Cell metabolism gene	MRPL55	HSD17B10	0.879575268	1.59E-40
THYM	Cell metabolism gene	MRPL55	ACOT8	0.879624997	1.56E-40
THYM	Cell metabolism gene	MRPL55	MIF	0.880405084	1.08E-40
THYM	Cell metabolism gene	MRPL55	PPOX	0.881316012	7.02E-41
THYM	Cell metabolism gene	MRPL55	POLR2H	0.882511707	3.97E-41
THYM	Cell metabolism gene	MRPL55	PHPT1	0.8829914	3.15E-41
THYM	Cell metabolism gene	MRPL55	PSMB3	0.8835065	2.46E-41
THYM	Cell metabolism gene	MRPL55	APRT	0.885936642	7.47E-42
THYM	Cell metabolism gene	MRPL55	ATP5G1	0.891231455	5.07E-43
THYM	Cell metabolism gene	MRPL55	EXOSC4	0.892795282	2.23E-43
THYM	Cell metabolism gene	MRPL55	PGLS	0.89293901	2.07E-43
THYM	Cell metabolism gene	MRPL55	POLR2J	0.898312242	1.11E-44
THYM	Cell metabolism gene	MRPL55	WBSCR22	0.901275591	2.06E-45
THYM	Cell metabolism gene	MRPL55	GUK1	0.905419089	1.78E-46
THYM	Cell metabolism gene	MRPL55	PSMB4	0.906893544	7.27E-47
THYM	Cell metabolism gene	MRPL55	TIMM50	0.915118555	3.63E-49
THYM	Cell metabolism gene	MRPL55	PSMD4	0.929867713	6.01E-54
THYM	Cell metabolism gene	MRPL55	MTX1	0.938751286	2.32E-57
THYM	Cell metabolism gene	MRPL55	DPM3	0.946124413	1.31E-60
THYM	Cell metabolism gene	MRPL55	POLR2I	0.94855609	8.85E-62
THYM	CGC	MRPL55	RBM10	0.800210283	2.04E-28
THYM	CGC	MRPL55	SDHAF2	0.800352372	1.97E-28
THYM	CGC	MRPL55	MGMT	0.80974728	1.47E-29
THYM	CGC	MRPL55	TFPT	0.823381853	2.62E-31
THYM	CGC	MRPL55	COX6C	0.871678963	5.65E-39
THYM	Epifactor	MRPL55	FBL	0.803699534	7.94E-29
THYM	Epifactor	MRPL55	C17orf49	0.811244044	9.62E-30
THYM	Epifactor	MRPL55	TFPT	0.823381853	2.62E-31
THYM	Epifactor	MRPL55	CCDC101	0.825151482	1.52E-31
THYM	Epifactor	MRPL55	PAF1	0.827846474	6.50E-32
THYM	Epifactor	MRPL55	ZGPAT	0.829652204	3.66E-32
THYM	Epifactor	MRPL55	EXOSC5	0.843116711	4.00E-34
THYM	Epifactor	MRPL55	LAS1L	0.845073981	2.00E-34
THYM	Epifactor	MRPL55	INO80E	0.852432481	1.36E-35
THYM	Epifactor	MRPL55	CDK5	0.861750694	3.63E-37
THYM	Epifactor	MRPL55	TAF10	0.870237662	1.06E-38
THYM	Epifactor	MRPL55	BRMS1	0.877384167	4.40E-40
THYM	Epifactor	MRPL55	SIRT6	0.879547722	1.62E-40
THYM	Epifactor	MRPL55	PRPF31	0.888116818	2.51E-42
THYM	Epifactor	MRPL55	EXOSC4	0.892795282	2.23E-43
THYM	Epifactor	MRPL55	ZNHIT1	0.918098323	4.65E-50
THYM	IUPHAR	MRPL55	FKBP1A	0.80518355	5.28E-29
THYM	IUPHAR	MRPL55	SLC27A5	0.810634726	1.14E-29
THYM	IUPHAR	MRPL55	DGAT1	0.818345363	1.21E-30
THYM	IUPHAR	MRPL55	PSMB6	0.820394146	6.53E-31
THYM	IUPHAR	MRPL55	SLC39A3	0.820923875	5.56E-31
THYM	IUPHAR	MRPL55	SIRT3	0.823224839	2.75E-31
THYM	IUPHAR	MRPL55	ADCK5	0.835834753	4.84E-33
THYM	IUPHAR	MRPL55	HMOX2	0.837736696	2.55E-33
THYM	IUPHAR	MRPL55	ATP6V0B	0.843408726	3.61E-34
THYM	IUPHAR	MRPL55	PTGES2	0.844702758	2.28E-34
THYM	IUPHAR	MRPL55	PMVK	0.848969622	4.91E-35
THYM	IUPHAR	MRPL55	PHKG2	0.853941212	7.69E-36
THYM	IUPHAR	MRPL55	ABCB8	0.8547686	5.61E-36
THYM	IUPHAR	MRPL55	CDK5	0.861750694	3.63E-37
THYM	IUPHAR	MRPL55	SIRT6	0.879547722	1.62E-40
THYM	Kinase	MRPL55	ADCK5	0.835834753	4.84E-33
THYM	Kinase	MRPL55	PHKG2	0.853941212	7.69E-36
THYM	Kinase	MRPL55	CDK5	0.861750694	3.63E-37
THYM	Kinase	MRPL55	FASTK	0.907689221	4.45E-47
THYM	TF	MRPL55	THAP8	0.807947949	2.45E-29
THYM	TF	MRPL55	ZNF692	0.809109804	1.76E-29
THYM	TF	MRPL55	IRF3	0.81179172	8.22E-30
THYM	TF	MRPL55	ZNF32	0.81362213	4.85E-30
THYM	TF	MRPL55	ZGPAT	0.829652204	3.66E-32
THYM	TF	MRPL55	DRAP1	0.837438429	2.82E-33
THYM	TF	MRPL55	ZNF581	0.843596771	3.38E-34
THYM	TF	MRPL55	USF1	0.855895007	3.64E-36
THYM	TF	MRPL55	ZNF524	0.860229885	6.67E-37
THYM	TF	MRPL55	THAP7	0.862240849	2.98E-37
THYM	TF	MRPL55	ZNF688	0.873389134	2.66E-39
THYM	TF	MRPL55	ZNF787	0.879538669	1.62E-40
THYM	TF	MRPL55	GLI4	0.889146997	1.49E-42
THYM	TSG	MRPL55	PARK7	0.802420721	1.12E-28
THYM	TSG	MRPL55	GSTP1	0.807482968	2.79E-29
THYM	TSG	MRPL55	IRF3	0.81179172	8.22E-30
THYM	TSG	MRPL55	SIRT3	0.823224839	2.75E-31
THYM	TSG	MRPL55	TSSC4	0.843306585	3.74E-34
THYM	TSG	MRPL55	ST20	0.845195344	1.92E-34
THYM	TSG	MRPL55	NPRL2	0.851991683	1.60E-35
THYM	TSG	MRPL55	GABARAP	0.860984447	4.94E-37
THYM	TSG	MRPL55	STUB1	0.871286817	6.70E-39
THYM	TSG	MRPL55	BRMS1	0.877384167	4.40E-40
THYM	TSG	MRPL55	SIRT6	0.879547722	1.62E-40
THYM	TSG	MRPL55	GADD45GIP1	0.920524716	8.24E-51
UCEC	Cell metabolism gene	MRPL55	DPM3	0.801749147	2.30E-46
UCEC	Cell metabolism gene	MRPL55	MTX1	0.826819463	1.27E-51
UCEC	Cell metabolism gene	MRPL55	GUK1	0.839458514	1.32E-54
UCEC	Epifactor	MRPL55	ZNHIT1	0.825557437	2.44E-51
UCEC	Kinase	MRPL55	FASTK	0.806134952	3.14E-47
UCS	Cell metabolism gene	MRPL55	PFDN2	0.801452914	1.46E-28
UCS	Cell metabolism gene	MRPL55	LCMT1	0.801841249	1.32E-28
UCS	Cell metabolism gene	MRPL55	COX17	0.802331795	1.15E-28
UCS	Cell metabolism gene	MRPL55	TOMM22	0.805667291	4.62E-29
UCS	Cell metabolism gene	MRPL55	DHRS4L2	0.806832293	3.34E-29
UCS	Cell metabolism gene	MRPL55	LSM4	0.807269077	2.96E-29
UCS	Cell metabolism gene	MRPL55	DGUOK	0.807340594	2.90E-29
UCS	Cell metabolism gene	MRPL55	GSTP1	0.807482968	2.79E-29
UCS	Cell metabolism gene	MRPL55	ALG3	0.80957079	1.55E-29
UCS	Cell metabolism gene	MRPL55	DHRS4	0.809962772	1.39E-29
UCS	Cell metabolism gene	MRPL55	SLC27A5	0.810634726	1.14E-29
UCS	Cell metabolism gene	MRPL55	DOHH	0.81115112	9.88E-30
UCS	Cell metabolism gene	MRPL55	PSMB10	0.812189223	7.34E-30
UCS	Cell metabolism gene	MRPL55	PFDN5	0.814812426	3.43E-30
UCS	Cell metabolism gene	MRPL55	DGAT1	0.818345363	1.21E-30
UCS	Cell metabolism gene	MRPL55	UROS	0.818627495	1.11E-30
UCS	Cell metabolism gene	MRPL55	HMBS	0.81874834	1.07E-30
UCS	Cell metabolism gene	MRPL55	IDH3G	0.819586828	8.33E-31
UCS	Cell metabolism gene	MRPL55	PSMB6	0.820394146	6.53E-31
UCS	Cell metabolism gene	MRPL55	PGP	0.8208634	5.66E-31
UCS	Cell metabolism gene	MRPL55	TSTA3	0.822706692	3.23E-31
UCS	Cell metabolism gene	MRPL55	TAZ	0.823983623	2.18E-31
UCS	Cell metabolism gene	MRPL55	CYC1	0.825743706	1.26E-31
UCS	Cell metabolism gene	MRPL55	SRM	0.825774118	1.25E-31
UCS	Cell metabolism gene	MRPL55	FAU	0.826252083	1.08E-31
UCS	Cell metabolism gene	MRPL55	PMPCA	0.826279759	1.07E-31
UCS	Cell metabolism gene	MRPL55	GEMIN6	0.830972116	2.39E-32
UCS	Cell metabolism gene	MRPL55	SSR4	0.831681794	1.90E-32
UCS	Cell metabolism gene	MRPL55	POLE4	0.836844268	3.45E-33
UCS	Cell metabolism gene	MRPL55	HMOX2	0.837736696	2.55E-33
UCS	Cell metabolism gene	MRPL55	POLR2F	0.842468052	5.02E-34
UCS	Cell metabolism gene	MRPL55	ITPA	0.842484793	4.99E-34
UCS	Cell metabolism gene	MRPL55	EXOSC5	0.843116711	4.00E-34
UCS	Cell metabolism gene	MRPL55	PSMB7	0.843497307	3.50E-34
UCS	Cell metabolism gene	MRPL55	TBCB	0.843808885	3.13E-34
UCS	Cell metabolism gene	MRPL55	PSMC5	0.843824218	3.12E-34
UCS	Cell metabolism gene	MRPL55	PTGES2	0.844702758	2.28E-34
UCS	Cell metabolism gene	MRPL55	PPCDC	0.845523889	1.71E-34
UCS	Cell metabolism gene	MRPL55	PMVK	0.848969622	4.91E-35
UCS	Cell metabolism gene	MRPL55	PHKG2	0.853941212	7.69E-36
UCS	Cell metabolism gene	MRPL55	PSMC1	0.854216597	6.93E-36
UCS	Cell metabolism gene	MRPL55	TIMM8B	0.855068368	5.01E-36
UCS	Cell metabolism gene	MRPL55	MED27	0.855099044	4.95E-36
UCS	Cell metabolism gene	MRPL55	GSTZ1	0.860615197	5.72E-37
UCS	Cell metabolism gene	MRPL55	GMPPA	0.862415845	2.77E-37
UCS	Cell metabolism gene	MRPL55	NANS	0.862816846	2.36E-37
UCS	Cell metabolism gene	MRPL55	EBP	0.863139139	2.07E-37
UCS	Cell metabolism gene	MRPL55	SNRPD2	0.863199335	2.02E-37
UCS	Cell metabolism gene	MRPL55	TIMM10	0.864616487	1.13E-37
UCS	Cell metabolism gene	MRPL55	DPM2	0.866310623	5.59E-38
UCS	Cell metabolism gene	MRPL55	TIMM13	0.867323101	3.66E-38
UCS	Cell metabolism gene	MRPL55	PSME2	0.86926791	1.60E-38
UCS	Cell metabolism gene	MRPL55	TOMM40	0.871656247	5.70E-39
UCS	Cell metabolism gene	MRPL55	GEMIN7	0.872226541	4.44E-39
UCS	Cell metabolism gene	MRPL55	TIMM17B	0.875187061	1.19E-39
UCS	Cell metabolism gene	MRPL55	HSD17B10	0.879575268	1.59E-40
UCS	Cell metabolism gene	MRPL55	ACOT8	0.879624997	1.56E-40
UCS	Cell metabolism gene	MRPL55	MIF	0.880405084	1.08E-40
UCS	Cell metabolism gene	MRPL55	PPOX	0.881316012	7.02E-41
UCS	Cell metabolism gene	MRPL55	POLR2H	0.882511707	3.97E-41
UCS	Cell metabolism gene	MRPL55	PHPT1	0.8829914	3.15E-41
UCS	Cell metabolism gene	MRPL55	PSMB3	0.8835065	2.46E-41
UCS	Cell metabolism gene	MRPL55	APRT	0.885936642	7.47E-42
UCS	Cell metabolism gene	MRPL55	ATP5G1	0.891231455	5.07E-43
UCS	Cell metabolism gene	MRPL55	EXOSC4	0.892795282	2.23E-43
UCS	Cell metabolism gene	MRPL55	PGLS	0.89293901	2.07E-43
UCS	Cell metabolism gene	MRPL55	POLR2J	0.898312242	1.11E-44
UCS	Cell metabolism gene	MRPL55	WBSCR22	0.901275591	2.06E-45
UCS	Cell metabolism gene	MRPL55	GUK1	0.905419089	1.78E-46
UCS	Cell metabolism gene	MRPL55	PSMB4	0.906893544	7.27E-47
UCS	Cell metabolism gene	MRPL55	TIMM50	0.915118555	3.63E-49
UCS	Cell metabolism gene	MRPL55	PSMD4	0.929867713	6.01E-54
UCS	Cell metabolism gene	MRPL55	MTX1	0.938751286	2.32E-57
UCS	Cell metabolism gene	MRPL55	DPM3	0.946124413	1.31E-60
UCS	Cell metabolism gene	MRPL55	POLR2I	0.94855609	8.85E-62
UCS	CGC	MRPL55	RBM10	0.800210283	2.04E-28
UCS	CGC	MRPL55	SDHAF2	0.800352372	1.97E-28
UCS	CGC	MRPL55	MGMT	0.80974728	1.47E-29
UCS	CGC	MRPL55	TFPT	0.823381853	2.62E-31
UCS	CGC	MRPL55	COX6C	0.871678963	5.65E-39
UCS	Epifactor	MRPL55	FBL	0.803699534	7.94E-29
UCS	Epifactor	MRPL55	C17orf49	0.811244044	9.62E-30
UCS	Epifactor	MRPL55	TFPT	0.823381853	2.62E-31
UCS	Epifactor	MRPL55	CCDC101	0.825151482	1.52E-31
UCS	Epifactor	MRPL55	PAF1	0.827846474	6.50E-32
UCS	Epifactor	MRPL55	ZGPAT	0.829652204	3.66E-32
UCS	Epifactor	MRPL55	EXOSC5	0.843116711	4.00E-34
UCS	Epifactor	MRPL55	LAS1L	0.845073981	2.00E-34
UCS	Epifactor	MRPL55	INO80E	0.852432481	1.36E-35
UCS	Epifactor	MRPL55	CDK5	0.861750694	3.63E-37
UCS	Epifactor	MRPL55	TAF10	0.870237662	1.06E-38
UCS	Epifactor	MRPL55	BRMS1	0.877384167	4.40E-40
UCS	Epifactor	MRPL55	SIRT6	0.879547722	1.62E-40
UCS	Epifactor	MRPL55	PRPF31	0.888116818	2.51E-42
UCS	Epifactor	MRPL55	EXOSC4	0.892795282	2.23E-43
UCS	Epifactor	MRPL55	ZNHIT1	0.918098323	4.65E-50
UCS	IUPHAR	MRPL55	FKBP1A	0.80518355	5.28E-29
UCS	IUPHAR	MRPL55	SLC27A5	0.810634726	1.14E-29
UCS	IUPHAR	MRPL55	DGAT1	0.818345363	1.21E-30
UCS	IUPHAR	MRPL55	PSMB6	0.820394146	6.53E-31
UCS	IUPHAR	MRPL55	SLC39A3	0.820923875	5.56E-31
UCS	IUPHAR	MRPL55	SIRT3	0.823224839	2.75E-31
UCS	IUPHAR	MRPL55	ADCK5	0.835834753	4.84E-33
UCS	IUPHAR	MRPL55	HMOX2	0.837736696	2.55E-33
UCS	IUPHAR	MRPL55	ATP6V0B	0.843408726	3.61E-34
UCS	IUPHAR	MRPL55	PTGES2	0.844702758	2.28E-34
UCS	IUPHAR	MRPL55	PMVK	0.848969622	4.91E-35
UCS	IUPHAR	MRPL55	PHKG2	0.853941212	7.69E-36
UCS	IUPHAR	MRPL55	ABCB8	0.8547686	5.61E-36
UCS	IUPHAR	MRPL55	CDK5	0.861750694	3.63E-37
UCS	IUPHAR	MRPL55	SIRT6	0.879547722	1.62E-40
UCS	Kinase	MRPL55	ADCK5	0.835834753	4.84E-33
UCS	Kinase	MRPL55	PHKG2	0.853941212	7.69E-36
UCS	Kinase	MRPL55	CDK5	0.861750694	3.63E-37
UCS	Kinase	MRPL55	FASTK	0.907689221	4.45E-47
UCS	TF	MRPL55	THAP8	0.807947949	2.45E-29
UCS	TF	MRPL55	ZNF692	0.809109804	1.76E-29
UCS	TF	MRPL55	IRF3	0.81179172	8.22E-30
UCS	TF	MRPL55	ZNF32	0.81362213	4.85E-30
UCS	TF	MRPL55	ZGPAT	0.829652204	3.66E-32
UCS	TF	MRPL55	DRAP1	0.837438429	2.82E-33
UCS	TF	MRPL55	ZNF581	0.843596771	3.38E-34
UCS	TF	MRPL55	USF1	0.855895007	3.64E-36
UCS	TF	MRPL55	ZNF524	0.860229885	6.67E-37
UCS	TF	MRPL55	THAP7	0.862240849	2.98E-37
UCS	TF	MRPL55	ZNF688	0.873389134	2.66E-39
UCS	TF	MRPL55	ZNF787	0.879538669	1.62E-40
UCS	TF	MRPL55	GLI4	0.889146997	1.49E-42
UCS	TSG	MRPL55	PARK7	0.802420721	1.12E-28
UCS	TSG	MRPL55	GSTP1	0.807482968	2.79E-29
UCS	TSG	MRPL55	IRF3	0.81179172	8.22E-30
UCS	TSG	MRPL55	SIRT3	0.823224839	2.75E-31
UCS	TSG	MRPL55	TSSC4	0.843306585	3.74E-34
UCS	TSG	MRPL55	ST20	0.845195344	1.92E-34
UCS	TSG	MRPL55	NPRL2	0.851991683	1.60E-35
UCS	TSG	MRPL55	GABARAP	0.860984447	4.94E-37
UCS	TSG	MRPL55	STUB1	0.871286817	6.70E-39
UCS	TSG	MRPL55	BRMS1	0.877384167	4.40E-40
UCS	TSG	MRPL55	SIRT6	0.879547722	1.62E-40
UCS	TSG	MRPL55	GADD45GIP1	0.920524716	8.24E-51
UVM	Cell metabolism gene	MRPL55	ATP5G1	0.806334856	1.80E-19
UVM	Cell metabolism gene	MRPL55	POLR2J	0.813166686	5.10E-20
UVM	Cell metabolism gene	MRPL55	MTX1	0.81475524	3.77E-20
UVM	Cell metabolism gene	MRPL55	POLR2I	0.820664805	1.20E-20
UVM	Cell metabolism gene	MRPL55	DPM3	0.848010591	3.28E-23
UVM	CGC	MRPL55	TFPT	0.817186281	2.37E-20
UVM	Epifactor	MRPL55	TFPT	0.817186281	2.37E-20
UVM	Epifactor	MRPL55	ZNHIT1	0.832336314	1.10E-21
UVM	TF	MRPL55	THAP7	0.800655527	4.95E-19
UVM	TF	MRPL55	SLC2A4RG	0.818091335	1.99E-20
UVM	TSG	MRPL55	GADD45GIP1	0.846833062	4.33E-23

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
LIHC	MRPL55	MRPL10	-3.22703617995931	0.000209845686767642
KIRP	MRPL55	MRPL51	-1.32840656722761	0.000213860534131527
LUSC	MRPL55	MRPL39	-3.50411737429004	0.000985010025625636
KIRC	MRPL55	MRPL46	-7.36081421944909	0.0011460554764592
KIRP	MRPL55	MRPL46	-7.17671685013906	0.00123529229313135
COAD	MRPL55	MRPL41	-2.99561502382389	0.00144392251968384
CHOL	MRPL55	MRPL41	-4.96379377542225	0.00390625
CHOL	MRPL55	MRPL46	-2.73791743817321	0.00390625
BLCA	MRPL55	MRPL39	1.69896851960452	0.00391769409179688
LUAD	MRPL55	MRPL39	-1.1049452981592	0.00471395891927286
THCA	MRPL55	MRPL41	-3.88188543554269	0.00492925389458784
KIRP	MRPL55	MRPL28	1.10848699852281	0.00779616041108966
PRAD	MRPL55	ICT1	-1.54848444909352	0.00907723161841939
COAD	MRPL55	MRPL51	-1.84147877110728	0.0110453069210053
STAD	MRPL55	MRPL10	-4.87461667395871	0.0118026207201183
COAD	MRPL55	MRPL39	-1.15285953291756	0.0357243716716767
LUSC	MRPL55	MRPL28	-2.17870242177449	1.51941378521463e-05
LUSC	MRPL55	MRPL10	-2.440715746941	1.79996309233889e-05
BRCA	MRPL55	ICT1	-4.17488220449664	2.73719348917167e-14
LUSC	MRPL55	MRPL40	-8.45997214407498	3.09303724812157e-05
PRAD	MRPL55	MRPL37	-2.21074342735295	3.65283830814974e-07
LUAD	MRPL55	MRPL37	-2.86549200993971	3.76287422734829e-10
LIHC	MRPL55	MRPL39	-1.65461683386216	3.95799979560965e-08
LUAD	MRPL55	MRPL10	-5.60579373211551	4.11637918366747e-07
PRAD	MRPL55	MRPL41	1.31179686307216	4.41809300064344e-05
LUSC	MRPL55	MRPL52	-1.62632647251357	5.03439574503487e-05
BRCA	MRPL55	MRPL51	-2.91631474502369	5.42627121034746e-18
LUAD	MRPL55	MRPL52	-3.10528494524096	5.46286040022975e-07
LUAD	MRPL55	MRPL28	-1.41031503837636	5.67286357063566e-05
LUSC	MRPL55	ICT1	-3.23093376049456	6.60526357089358e-07
KICH	MRPL55	MRPL41	1.05103651319563	7.49826431274414e-05
KIRC	MRPL55	MRPL51	-1.59773648669469	8.46797387064351e-07
BRCA	MRPL55	MRPL37	-3.79079551418026	9.33185484212232e-10
LUAD	MRPL55	MRPL51	-1.44585271087263	9.92276876427582e-07

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with MRPL55

ICT1, MRPL23, MRPL32, MRPS9, MRPL13, MRPL52, MRPL39, MRPL51, MRPL41, MRPL9, MRPL3, MRPL15, HNRNPM, TOMM40, ILF2, FLOT1, RPS23, ILF3, RPL13, RBMS3, MRPL28, HNRNPDL, MRPL46, MRPL4, MRPL37, MRPS30, MRPL47, MRPL40, MRPL48, HNRNPD, MYO1C, PLK1, RAB5C, SORT1, CBX4, CHORDC1, MRPL50, UGGT1, PARD6B, BAG6, Rab5c, Cdc26, Cdca5, Cdkn2aip, MRPL10, MRPL42, MRPL12, MRPL35, PRKCZ, MEPCE, RECQL4, MRM1, LTN1, SNRNP70, TNK2, ORF8, IMMP2L, ACAD9, AUH, C12orf65, C1QBP, C21orf33, C6orf203, CS, GFM1, HINT2, MDH2, METTL15, METTL17, MRPL11, MRPS12, MRPS26, MRRF, MTERF3, MTG2, MTIF2, MTIF3, MTRF1, MTRF1L, PMPCA, PMPCB, RPUSD4, SLIRP, SSBP1, TACO1, TBRG4, TFAM, TRUB2, TSFM, VWA8, CLPP, MAFB, AARS2, FZR1, RPL19, MRPL2, RBMS2, HNRNPU, SRSF4, MALSU1, H1FNT, RPL37, MRPL30, MRPL53, SRSF3, RPL27A, MRPL18, RPL13A, RPL17, YBX2, SRSF7, RPS8, RPL4, RPL23A, RPL35, MRPS18A, RPL10, FAHD1, MRPL27, LIN28A, GADD45GIP1,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
MRPL55	chr1	228295369	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
MRPL55	ESCA	chr1	228294529	228294529	C	T	Missense_Mutation	p.E143K	3
MRPL55	UCEC	chr1	228295393	228295393	G	A	Silent	p.Y104	2
MRPL55	UCEC	chr1	228295714	228295714	C	T	Missense_Mutation	p.R33Q	2
MRPL55	ESCA	chr1	228294529	228294529	C	T	Missense_Mutation		2
MRPL55	UCEC	chr1	228294562	228294562	G	A	Missense_Mutation	p.R132C	2
MRPL55	SARC	chr1	228295766	228295766	G	T	Missense_Mutation	p.L16I	1
MRPL55	COAD	chr1	228294496	228294496	G	A	Missense_Mutation	p.R118C	1
MRPL55	LIHC	chr1	228295527	228295527	G	A	Missense_Mutation		1
MRPL55	SKCM	chr1	228295420	228295420	C	T	Silent	p.Q59Q	1
MRPL55	COAD	chr1	228294608	228294608	A	G	Silent	p.D80D	1
MRPL55	LIHC	chr1	228295447	228295447	T	C	Silent		1
MRPL55	SKCM	chr1	228295508	228295508	G	A	Missense_Mutation	p.S66F	1
MRPL55	COAD	chr1	228295518	228295518	G	A	Missense_Mutation	p.H27Y	1
MRPL55	LIHC	chr1	228294574	228294574	T	C	Missense_Mutation		1
MRPL55	SKCM	chr1	228295420	228295420	C	T	Silent	p.Q95Q	1
MRPL55	LIHC	chr1	228295710	228295710	G	C	Silent	p.G34G	1
MRPL55	STAD	chr1	228294543	228294543	G	A	Missense_Mutation	p.S138L	1
MRPL55	LUAD	chr1	228294558	228294558	T	C	Missense_Mutation	p.E133G	1
MRPL55	STAD	chr1	228295438	228295438	G	T	Silent	p.P89P	1
MRPL55	GBM	chr1	228294495	228294495	C	T	Missense_Mutation	p.R154H	1
MRPL55	LUAD	chr1	228294558	228294558	T	C	Missense_Mutation	p.E97G	1
MRPL55	STAD	chr1	228294490	228294490	G	A	Nonsense_Mutation	p.R156X	1
MRPL55	HNSC	chr1	228295553	228295553	G	A	Missense_Mutation	p.T51I	1
MRPL55	LUSC	chr1	228295503	228295503	G	A	Nonsense_Mutation	p.R68*	1
MRPL55	STAD	chr1	228295696	228295696	C	A	Missense_Mutation	p.G39V	1
MRPL55	HNSC	chr1	228295431	228295431	G	T	Missense_Mutation	p.L92M	1
MRPL55	SARC	chr1	228295766	228295766	G	T	Missense_Mutation		1
MRPL55	BLCA	chr1	228295526	228295526	C	T	Missense_Mutation		1
MRPL55	STAD	chr1	228294490	228294490	G	A	Nonsense_Mutation	p.R120*	1
MRPL55	HNSC	chr1	228295553	228295553	G	A	Missense_Mutation	p.T15I	1
MRPL55	SARC	chr1	228295982	228295982	G	T	Missense_Mutation		1
MRPL55	BLCA	chr1	228294489	228294489	C	T	Missense_Mutation		1
MRPL55	STAD	chr1	228294543	228294543	G	A	Missense_Mutation	p.S102L	1
MRPL55	LGG	chr1	228294577	228294577	C	T	Missense_Mutation	p.A127T	1
MRPL55	SARC	chr1	228294568	228294568	G	A	Missense_Mutation		1
MRPL55	BLCA	chr1	228295526	228295526	C	T	Missense_Mutation	p.R60H	1
MRPL55	LGG	chr1	228294577	228294577	C	T	Missense_Mutation		1

Copy number variation (CNV) of MRPL55
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across MRPL55
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
82676	N/A	AI086220	SLC25A39	chr17	42397139	+	MRPL55	chr1	228296954	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRP	MRPL55	0.00043119134629712	0.012
ESCA	MRPL55	0.00647359917724973	0.17
THCA	MRPL55	0.0131243840815287	0.34
CHOL	MRPL55	0.0176522768243	0.44
COAD	MRPL55	0.0179828150599067	0.44
LIHC	MRPL55	0.023106186679873	0.53
HNSC	MRPL55	0.0306058091319885	0.67

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUAD	MRPL55	0.04173958251366	1
LUSC	MRPL55	0.0134169117527015	0.42
THCA	MRPL55	0.00164052725645125	0.052
LGG	MRPL55	0.000263319073976367	0.0087

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source