Home

Download

Statistics

Examples

Help

Contact

	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: DHX9 (NCBI Gene ID:1660)

Gene Summary

Gene Summary

Gene Information	Gene Name: DHX9
	Gene ID: 1660
	Gene Symbol	DHX9
	Gene ID	1660
	Gene Name	DExH-box helicase 9
	Synonyms	DDX9\|LKP\|NDH2\|NDHII\|RHA
	Cytomap	1q25.3
	Type of Gene	protein-coding
	Description	ATP-dependent RNA helicase ADEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 9DEAH (Asp-Glu-Ala-His) box helicase 9DEAH (Asp-Glu-Ala-His) box polypeptide 9DEAH box protein 9DEAH-box helicase 9RNA helicase Aleukophysinnuclear DNA helicase II
	Modification date	20200322
	UniProtAcc	Q08211

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0017148	Negative regulation of translation
GO:0006417	Regulation of translation
GO:0005840	Ribosome
GO:0045727	Positive regulation of translation
GO:0002181	Cytoplasmic translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	DHX9	GO:0010501	RNA secondary structure unwinding	1537828\|9111062
Hgene	DHX9	GO:0032508	DNA duplex unwinding	9111062\|21561811
Hgene	DHX9	GO:0034622	cellular protein-containing complex assembly	23361462
Hgene	DHX9	GO:0039695	DNA-templated viral transcription	11096080
Hgene	DHX9	GO:0044806	G-quadruplex DNA unwinding	21561811
Hgene	DHX9	GO:0046833	positive regulation of RNA export from nucleus	11402034
Hgene	DHX9	GO:0050434	positive regulation of viral transcription	11096080
Hgene	DHX9	GO:0050684	regulation of mRNA processing	28355180
Hgene	DHX9	GO:2000765	regulation of cytoplasmic translation	28355180

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
DHX9	>1119.25

Top

Translation Studies in PubMed

We searched PubMed using 'DHX9[title] AND translation [title] AND human.'

Gene	Title	PMID
DHX9	The Host DHX9 DExH-Box Helicase Is Recruited to Chikungunya Virus Replication Complexes for Optimal Genomic RNA Translation	30463980

Top

Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000367549	182812428	182812569	In-frame
ENST00000367549	182829127	182829319	In-frame
ENST00000367549	182848384	182848545	Frame-shift
ENST00000367549	182849631	182849743	Frame-shift
ENST00000367549	182852654	182852770	Frame-shift
ENST00000367549	182853747	182853948	In-frame

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000367549	182812428	182812569	4257	222	362	1270	37	84
ENST00000367549	182829127	182829319	4257	1251	1442	1270	380	444
ENST00000367549	182853747	182853948	4257	3371	3571	1270	1087	1153

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc	Exon skip start (AA)	Exon Skip end (AA)	Function feature start (AA)	Function feature end (AA)	Functional feature type	Functional feature desc.
Q08211	380	444	1	1270	Chain	ID=PRO_0000055157;Note=ATP-dependent RNA helicase A
Q08211	37	84	1	1270	Chain	ID=PRO_0000055157;Note=ATP-dependent RNA helicase A
Q08211	1087	1153	1	1270	Chain	ID=PRO_0000055157;Note=ATP-dependent RNA helicase A
Q08211	37	84	3	71	Domain	Note=DRBM 1;Ontology_term=ECO:0000255,ECO:0000269,ECO:0000269;evidence=ECO:0000255\|PROSITE-ProRule:PRU00266,ECO:0000269\|PubMed:23361462,ECO:0000269\|PubMed:9111062;Dbxref=PMID:23361462,PMID:9111062
Q08211	380	444	398	564	Domain	Note=Helicase ATP-binding;Ontology_term=ECO:0000255,ECO:0000269;evidence=ECO:0000255\|PROSITE-ProRule:PRU00541,ECO:0000269\|PubMed:20510246;Dbxref=PMID:20510246
Q08211	380	444	411	419	Nucleotide binding	Note=ATP;Ontology_term=ECO:0000244,ECO:0000269,ECO:0000269;evidence=ECO:0000244\|PDB:3LLM,ECO:0000269\|PubMed:11416126,ECO:0000269\|PubMed:20510246;Dbxref=PMID:11416126,PMID:20510246
Q08211	37	84	1	250	Region	Note=Interaction with CREBBP;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:9323138;Dbxref=PMID:9323138
Q08211	37	84	53	55	Region	Note=siRNA-binding;Ontology_term=ECO:0000244,ECO:0000269;evidence=ECO:0000244\|PDB:3VYY,ECO:0000269\|PubMed:23361462;Dbxref=PMID:23361462
Q08211	380	444	255	664	Region	Note=Necessary for interaction with RNA polymerase II holoenzyme;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:9323138;Dbxref=PMID:9323138
Q08211	380	444	313	952	Region	Note=Necessary for interaction with H2AFX;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:15613478;Dbxref=PMID:15613478
Q08211	380	444	331	380	Region	Note=MTAD;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:11416126;Dbxref=PMID:11416126
Q08211	380	444	398	809	Region	Note=Core helicase;Ontology_term=ECO:0000305;evidence=ECO:0000305\|PubMed:25062910;Dbxref=PMID:25062910
Q08211	1087	1153	1150	1270	Region	Note=RGG;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269\|PubMed:10207077,ECO:0000269\|PubMed:25062910,ECO:0000269\|PubMed:25149208,ECO:0000269\|PubMed:9111062;Dbxref=PMID:10207077,PMID:25062910,PMID:25149208,PMID:9111062
Q08211	380	444	418	418	Metal binding	Note=Manganese;Ontology_term=ECO:0000244,ECO:0000269;evidence=ECO:0000244\|PDB:3LLM,ECO:0000269\|PubMed:20510246;Dbxref=PMID:20510246
Q08211	380	444	1	1035	Alternative sequence	ID=VSP_042314;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303\|PubMed:19054851,ECO:0000303\|PubMed:8690889;Dbxref=PMID:19054851,PMID:8690889
Q08211	37	84	1	1035	Alternative sequence	ID=VSP_042314;Note=In isoform 2. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303\|PubMed:19054851,ECO:0000303\|PubMed:8690889;Dbxref=PMID:19054851,PMID:8690889
Q08211	37	84	53	53	Mutagenesis	Note=Inhibits siRNA-binding and decreases interaction with AGO2%3B when associated with A-54 and A-55. N->A;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:23361462;Dbxref=PMID:23361462
Q08211	37	84	54	54	Mutagenesis	Note=Inhibits siRNA-binding and decreases interaction with AGO2%3B when associated with A-53 and A-55. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:23361462;Dbxref=PMID:23361462
Q08211	37	84	55	55	Mutagenesis	Note=Inhibits siRNA-binding and decreases interaction with AGO2%3B when associated with A-53 and A-54. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:23361462;Dbxref=PMID:23361462
Q08211	380	444	417	417	Mutagenesis	Note=Inhibits interaction with AGO2%2C DICER1 and TARBP2. Abrogates helicase activity and transcriptional activation. Does not inhibit binding to origins of DNA replication. K->R%2CN;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269\|PubMed:15355351,ECO:0000269\|PubMed:17531811,ECO:0000269\|PubMed:24990949,ECO:0000269\|PubMed:9323138;Dbxref=PMID:15355351,PMID:17531811,PMID:24990949,PMID:9323138
Q08211	380	444	417	417	Mutagenesis	Note=Reduces NUP98-induced mRNA transcription and alternative splicing activities. K->R;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:28221134;Dbxref=PMID:28221134
Q08211	1087	1153	1140	1140	Sequence conflict	Note=R->E;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q08211	37	84	31	39	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3VYY
Q08211	37	84	47	53	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3VYY
Q08211	37	84	54	71	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3VYY
Q08211	37	84	77	79	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3VYY
Q08211	380	444	376	386	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LLM
Q08211	380	444	389	393	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LLM
Q08211	380	444	394	403	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LLM
Q08211	380	444	405	410	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LLM
Q08211	380	444	417	431	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LLM
Q08211	380	444	435	437	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LLM
Q08211	380	444	439	446	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LLM

Top

Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
STAD	DHX9	-1.35515869279777	0.00016188295558095
BLCA	DHX9	2.25372387794619	0.00026702880859375

Top

Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type	Gene	miRNA	TargetScan binding score (Context++ score percentile)	Coefficient	Pvalue
PRAD	DHX9	hsa-miR-200b-3p	84	0.303334956183057	0.00677197400339881
UCEC	DHX9	hsa-miR-200b-3p	84	-0.341355337538374	0.0481803865080695

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
KICH	DHX9	-0.046345198	0.021033843
HNSC	DHX9	0.095291419	0.030484032
UCEC	DHX9	0.208540778	0.036456965

Top

Associated Genes

Strongly correlated genes belong to cellular important gene groups with DHX9 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
ACC	Cell metabolism gene	DHX9	NUP133	0.817295803	4.05E-20
ACC	Epifactor	DHX9	DDX21	0.800872733	8.00E-19
CHOL	Cell metabolism gene	DHX9	MED1	0.800420525	4.14E-11
CHOL	Cell metabolism gene	DHX9	NUP205	0.807299647	2.10E-11
CHOL	Cell metabolism gene	DHX9	POLR3C	0.808123123	1.93E-11
CHOL	Cell metabolism gene	DHX9	NUP133	0.815396537	9.09E-12
CHOL	Cell metabolism gene	DHX9	XRN2	0.818581911	6.47E-12
CHOL	Cell metabolism gene	DHX9	NCOA6	0.830715074	1.66E-12
CHOL	Cell metabolism gene	DHX9	POLA1	0.841156179	4.72E-13
CHOL	Cell metabolism gene	DHX9	EPRS	0.845452833	2.74E-13
CHOL	CGC	DHX9	BCL9	0.819470632	5.88E-12
CHOL	CGC	DHX9	ABL2	0.857032601	5.80E-14
CHOL	CGC	DHX9	FUBP1	0.864876252	1.87E-14
CHOL	Epifactor	DHX9	HCFC1	0.807679392	2.02E-11
CHOL	Epifactor	DHX9	ADNP	0.810325142	1.54E-11
CHOL	Epifactor	DHX9	ASH1L	0.811926955	1.31E-11
CHOL	Epifactor	DHX9	ZNF687	0.821990084	4.46E-12
CHOL	Epifactor	DHX9	NCOA6	0.830715074	1.66E-12
CHOL	Epifactor	DHX9	KDM5B	0.837006911	7.87E-13
CHOL	Epifactor	DHX9	TP53BP1	0.848881406	1.75E-13
CHOL	IUPHAR	DHX9	CSNK1G1	0.809321613	1.71E-11
CHOL	IUPHAR	DHX9	ASH1L	0.811926955	1.31E-11
CHOL	IUPHAR	DHX9	SLC39A10	0.818885241	6.26E-12
CHOL	IUPHAR	DHX9	KDM5B	0.837006911	7.87E-13
CHOL	IUPHAR	DHX9	DSTYK	0.839296431	5.95E-13
CHOL	IUPHAR	DHX9	ABL2	0.857032601	5.80E-14
CHOL	Kinase	DHX9	CSNK1G1	0.809321613	1.71E-11
CHOL	Kinase	DHX9	DSTYK	0.839296431	5.95E-13
CHOL	Kinase	DHX9	ABL2	0.857032601	5.80E-14
CHOL	TF	DHX9	ZFAT	0.801596076	3.69E-11
CHOL	TF	DHX9	E2F5	0.809888762	1.61E-11
CHOL	TF	DHX9	ADNP	0.810325142	1.54E-11
CHOL	TF	DHX9	ASH1L	0.811926955	1.31E-11
CHOL	TF	DHX9	ZBTB41	0.814998811	9.48E-12
CHOL	TF	DHX9	ZNF687	0.821990084	4.46E-12
CHOL	TF	DHX9	ZNF496	0.823778868	3.66E-12
CHOL	TF	DHX9	KDM5B	0.837006911	7.87E-13
CHOL	TF	DHX9	POGK	0.843929237	3.33E-13
CHOL	TSG	DHX9	CCAR1	0.816793204	7.84E-12
CHOL	TSG	DHX9	ANAPC1	0.823325526	3.85E-12
CHOL	TSG	DHX9	TP53BP1	0.848881406	1.75E-13
DLBC	Epifactor	DHX9	UCHL5	0.891233484	2.09E-17
KICH	Cell metabolism gene	DHX9	PIK3CB	0.824145762	1.08E-23
KICH	Cell metabolism gene	DHX9	NUP133	0.876230125	5.82E-30
KICH	CGC	DHX9	DEK	0.805308558	6.46E-22
KICH	CGC	DHX9	CREB1	0.81331319	1.20E-22
KICH	CGC	DHX9	CDC73	0.817031456	5.36E-23
KICH	CGC	DHX9	RFWD3	0.820769222	2.33E-23
KICH	CGC	DHX9	PIK3CB	0.824145762	1.08E-23
KICH	CGC	DHX9	FUBP1	0.833724941	1.12E-24
KICH	CGC	DHX9	STAG1	0.835728339	6.82E-25
KICH	CGC	DHX9	BCLAF1	0.84576415	5.20E-26
KICH	Epifactor	DHX9	RBBP5	0.802538637	1.13E-21
KICH	Epifactor	DHX9	BPTF	0.80495832	6.94E-22
KICH	Epifactor	DHX9	DEK	0.805308558	6.46E-22
KICH	Epifactor	DHX9	CDC73	0.817031456	5.36E-23
KICH	Epifactor	DHX9	SHPRH	0.834871113	8.43E-25
KICH	Epifactor	DHX9	EYA3	0.859478417	1.13E-27
KICH	Epifactor	DHX9	ASH1L	0.870034357	4.44E-29
KICH	IUPHAR	DHX9	BPTF	0.80495832	6.94E-22
KICH	IUPHAR	DHX9	PRPF4B	0.81643503	6.10E-23
KICH	IUPHAR	DHX9	PIK3CB	0.824145762	1.08E-23
KICH	IUPHAR	DHX9	ASH1L	0.870034357	4.44E-29
KICH	Kinase	DHX9	PRPF4B	0.81643503	6.10E-23
KICH	TF	DHX9	BPTF	0.80495832	6.94E-22
KICH	TF	DHX9	ETV3	0.806553944	5.00E-22
KICH	TF	DHX9	CREB1	0.81331319	1.20E-22
KICH	TF	DHX9	CDC5L	0.819442827	3.14E-23
KICH	TF	DHX9	RFX3	0.836414259	5.75E-25
KICH	TF	DHX9	ATF6	0.852254886	8.91E-27
KICH	TF	DHX9	ASH1L	0.870034357	4.44E-29
KICH	TSG	DHX9	PDS5B	0.805757137	5.89E-22
KICH	TSG	DHX9	CDC73	0.817031456	5.36E-23
KICH	TSG	DHX9	SHPRH	0.834871113	8.43E-25
KIRP	Cell metabolism gene	DHX9	NUP155	0.810872425	1.12E-76
KIRP	Cell metabolism gene	DHX9	KIF13A	0.812024488	4.64E-77
KIRP	CGC	DHX9	CDC73	0.800378374	2.59E-73
KIRP	CGC	DHX9	FUBP1	0.803757487	2.25E-74
KIRP	CGC	DHX9	STAG1	0.809108068	4.26E-76
KIRP	Epifactor	DHX9	CDC73	0.800378374	2.59E-73
KIRP	Epifactor	DHX9	RBBP5	0.806683373	2.61E-75
KIRP	IUPHAR	DHX9	SLC30A5	0.814075448	9.54E-78
KIRP	TF	DHX9	ATF6	0.821010483	3.91E-80
KIRP	TSG	DHX9	CDC73	0.800378374	2.59E-73
LAML	TSG	DHX9	XRCC5	0.821585415	1.36E-43
PCPG	Cell metabolism gene	DHX9	NUP155	0.819817782	1.15E-46
PCPG	Epifactor	DHX9	GTF2I	0.803487566	1.55E-43
PCPG	Epifactor	DHX9	RBBP5	0.861669102	2.15E-56
PCPG	TF	DHX9	ATF6	0.800174314	6.17E-43
PCPG	TF	DHX9	GTF2I	0.803487566	1.55E-43
TGCT	Cell metabolism gene	DHX9	GART	0.804782884	1.03E-36
TGCT	Cell metabolism gene	DHX9	POLR3A	0.813428613	4.52E-38
TGCT	Cell metabolism gene	DHX9	RQCD1	0.827412478	1.99E-40
TGCT	Cell metabolism gene	DHX9	NUP155	0.830206029	6.36E-41
TGCT	Cell metabolism gene	DHX9	NUP153	0.832172029	2.81E-41
TGCT	CGC	DHX9	N4BP2	0.807133271	4.49E-37
TGCT	Epifactor	DHX9	PPP4R2	0.809170906	2.16E-37
TGCT	Epifactor	DHX9	SMARCA5	0.818640796	6.33E-39
TGCT	Epifactor	DHX9	HCFC1	0.825668099	4.03E-40
TGCT	Epifactor	DHX9	GTF3C4	0.827102843	2.26E-40
TGCT	IUPHAR	DHX9	GART	0.804782884	1.03E-36
TGCT	IUPHAR	DHX9	SLC30A6	0.815150568	2.38E-38
TGCT	IUPHAR	DHX9	GTF3C4	0.827102843	2.26E-40
TGCT	TF	DHX9	ZNF281	0.819446848	4.64E-39
THCA	Cell metabolism gene	DHX9	PHAX	0.810956062	8.68E-135
THCA	Cell metabolism gene	DHX9	PAFAH1B2	0.826185882	3.72E-144
THCA	Cell metabolism gene	DHX9	POLR2B	0.845721815	1.32E-157
THCA	Cell metabolism gene	DHX9	XRN2	0.862758957	5.82E-171
THCA	CGC	DHX9	FUBP1	0.803422262	1.83E-130
THCA	CGC	DHX9	TRIP11	0.803634875	1.39E-130
THCA	CGC	DHX9	PBRM1	0.810170361	2.50E-134
THCA	CGC	DHX9	PAFAH1B2	0.826185882	3.72E-144
THCA	CGC	DHX9	STAG1	0.826364383	2.86E-144
THCA	Epifactor	DHX9	PBRM1	0.810170361	2.50E-134
THCA	Epifactor	DHX9	EYA3	0.814892759	3.99E-137
THCA	Epifactor	DHX9	CTR9	0.822862384	4.92E-142
THCA	Epifactor	DHX9	RBBP5	0.829465789	2.71E-146
THCA	Epifactor	DHX9	SMARCA5	0.843286753	7.88E-156
THCA	IUPHAR	DHX9	PBRM1	0.810170361	2.50E-134
THCA	IUPHAR	DHX9	SLC30A5	0.81194066	2.29E-135
THCA	IUPHAR	DHX9	ADAM10	0.832609532	2.19E-148
THCA	TF	DHX9	ZNF689	0.803850776	1.05E-130
THCA	TF	DHX9	ZNF134	0.814950919	3.68E-137
THCA	TSG	DHX9	PBRM1	0.810170361	2.50E-134
THCA	TSG	DHX9	RNF111	0.824575537	4.02E-143
THYM	Cell metabolism gene	DHX9	PGM2	0.801183367	1.57E-28
THYM	Cell metabolism gene	DHX9	GLS	0.80289431	9.89E-29
THYM	Cell metabolism gene	DHX9	MANEA	0.80357147	8.22E-29
THYM	Cell metabolism gene	DHX9	PIKFYVE	0.805432377	4.93E-29
THYM	Cell metabolism gene	DHX9	PGAM4	0.806456971	3.71E-29
THYM	Cell metabolism gene	DHX9	PIK3R4	0.806697064	3.47E-29
THYM	Cell metabolism gene	DHX9	PNPLA8	0.807459292	2.80E-29
THYM	Cell metabolism gene	DHX9	GLUD2	0.807574197	2.72E-29
THYM	Cell metabolism gene	DHX9	SEC24B	0.811628884	8.62E-30
THYM	Cell metabolism gene	DHX9	PI4K2B	0.813500989	5.02E-30
THYM	Cell metabolism gene	DHX9	DLAT	0.813834572	4.56E-30
THYM	Cell metabolism gene	DHX9	B3GNT2	0.815718731	2.63E-30
THYM	Cell metabolism gene	DHX9	ACAD8	0.820042158	7.26E-31
THYM	Cell metabolism gene	DHX9	TRMT11	0.821064805	5.33E-31
THYM	Cell metabolism gene	DHX9	DNMT1	0.832304818	1.55E-32
THYM	Cell metabolism gene	DHX9	FBXW2	0.837489585	2.78E-33
THYM	Cell metabolism gene	DHX9	MUT	0.837616123	2.66E-33
THYM	Cell metabolism gene	DHX9	BCKDHB	0.838403017	2.04E-33
THYM	Cell metabolism gene	DHX9	MTM1	0.839590644	1.36E-33
THYM	Cell metabolism gene	DHX9	MAT2B	0.842999468	4.17E-34
THYM	Cell metabolism gene	DHX9	PIP5K1A	0.84761582	8.03E-35
THYM	Cell metabolism gene	DHX9	NUP153	0.851369406	2.02E-35
THYM	Cell metabolism gene	DHX9	NUP107	0.855740366	3.87E-36
THYM	Cell metabolism gene	DHX9	SRP54	0.856819375	2.55E-36
THYM	Cell metabolism gene	DHX9	ACADM	0.86551398	7.79E-38
THYM	Cell metabolism gene	DHX9	NUP205	0.887670841	3.14E-42
THYM	Cell metabolism gene	DHX9	CDK8	0.908754961	2.29E-47
THYM	Cell metabolism gene	DHX9	XRN2	0.914345096	6.11E-49
THYM	Cell metabolism gene	DHX9	MED17	0.918261123	4.15E-50
THYM	Cell metabolism gene	DHX9	TGS1	0.928091992	2.56E-53
THYM	Cell metabolism gene	DHX9	POLR2B	0.930308451	4.18E-54
THYM	Cell metabolism gene	DHX9	RQCD1	0.945491504	2.60E-60
THYM	CGC	DHX9	BRD3	0.802381302	1.14E-28
THYM	CGC	DHX9	ATR	0.80258855	1.07E-28
THYM	CGC	DHX9	ZCCHC8	0.809118242	1.76E-29
THYM	CGC	DHX9	ERCC3	0.81186738	8.05E-30
THYM	CGC	DHX9	SETD2	0.813520064	5.00E-30
THYM	CGC	DHX9	THRAP3	0.814807535	3.43E-30
THYM	CGC	DHX9	CDC73	0.815048411	3.20E-30
THYM	CGC	DHX9	RB1	0.827415815	7.45E-32
THYM	CGC	DHX9	BRCA2	0.840079448	1.15E-33
THYM	CGC	DHX9	NUP98	0.841204334	7.79E-34
THYM	CGC	DHX9	RAD21	0.845068517	2.01E-34
THYM	CGC	DHX9	TRRAP	0.847959403	7.09E-35
THYM	CGC	DHX9	STAG1	0.849109961	4.66E-35
THYM	CGC	DHX9	VHL	0.858681172	1.23E-36
THYM	CGC	DHX9	BCOR	0.864067406	1.42E-37
THYM	CGC	DHX9	ATF1	0.868520061	2.20E-38
THYM	CGC	DHX9	MLLT10	0.870649641	8.83E-39
THYM	CGC	DHX9	FUBP1	0.906170105	1.13E-46
THYM	CGC	DHX9	TOP1	0.912850694	1.65E-48
THYM	Epifactor	DHX9	TP53BP1	0.800154058	2.07E-28
THYM	Epifactor	DHX9	TFDP1	0.801286275	1.53E-28
THYM	Epifactor	DHX9	BRD3	0.802381302	1.14E-28
THYM	Epifactor	DHX9	PHF8	0.802545178	1.09E-28
THYM	Epifactor	DHX9	ATR	0.80258855	1.07E-28
THYM	Epifactor	DHX9	SIRT1	0.808719423	1.97E-29
THYM	Epifactor	DHX9	PHF20L1	0.810315556	1.25E-29
THYM	Epifactor	DHX9	TAF4	0.812565773	6.58E-30
THYM	Epifactor	DHX9	SETD2	0.813520064	5.00E-30
THYM	Epifactor	DHX9	CDC73	0.815048411	3.20E-30
THYM	Epifactor	DHX9	SENP1	0.815851896	2.53E-30
THYM	Epifactor	DHX9	C11orf30	0.816082145	2.36E-30
THYM	Epifactor	DHX9	ACTR6	0.82206636	3.93E-31
THYM	Epifactor	DHX9	HLTF	0.823130747	2.83E-31
THYM	Epifactor	DHX9	ATXN7L3	0.824738633	1.72E-31
THYM	Epifactor	DHX9	GLYR1	0.824745469	1.72E-31
THYM	Epifactor	DHX9	DDX21	0.825192338	1.50E-31
THYM	Epifactor	DHX9	RB1	0.827415815	7.45E-32
THYM	Epifactor	DHX9	SMEK2	0.827728177	6.75E-32
THYM	Epifactor	DHX9	DNMT1	0.832304818	1.55E-32
THYM	Epifactor	DHX9	CUL2	0.83378848	9.54E-33
THYM	Epifactor	DHX9	MAP3K7	0.834867309	6.68E-33
THYM	Epifactor	DHX9	RCOR1	0.836892973	3.39E-33
THYM	Epifactor	DHX9	BRCA2	0.840079448	1.15E-33
THYM	Epifactor	DHX9	YY1	0.84295218	4.24E-34
THYM	Epifactor	DHX9	TRRAP	0.847959403	7.09E-35
THYM	Epifactor	DHX9	ZNF217	0.850130911	3.20E-35
THYM	Epifactor	DHX9	RBBP5	0.861970271	3.32E-37
THYM	Epifactor	DHX9	BCOR	0.864067406	1.42E-37
THYM	Epifactor	DHX9	DR1	0.866906238	4.36E-38
THYM	Epifactor	DHX9	ADNP	0.868522368	2.20E-38
THYM	Epifactor	DHX9	SMARCA5	0.869158455	1.68E-38
THYM	Epifactor	DHX9	EPC1	0.87031019	1.02E-38
THYM	Epifactor	DHX9	MLLT10	0.870649641	8.83E-39
THYM	Epifactor	DHX9	UCHL5	0.872279825	4.34E-39
THYM	Epifactor	DHX9	TADA2A	0.875543661	1.02E-39
THYM	Epifactor	DHX9	CTR9	0.877119307	4.96E-40
THYM	Epifactor	DHX9	TADA1	0.878789456	2.30E-40
THYM	Epifactor	DHX9	ZRANB3	0.883680522	2.26E-41
THYM	Epifactor	DHX9	SMARCAD1	0.886336961	6.13E-42
THYM	Epifactor	DHX9	RBBP4	0.89227697	2.94E-43
THYM	Epifactor	DHX9	TAF2	0.906470225	9.42E-47
THYM	IUPHAR	DHX9	BRD3	0.802381302	1.14E-28
THYM	IUPHAR	DHX9	PHF8	0.802545178	1.09E-28
THYM	IUPHAR	DHX9	ATR	0.80258855	1.07E-28
THYM	IUPHAR	DHX9	GLS	0.80289431	9.89E-29
THYM	IUPHAR	DHX9	NEK7	0.804589548	6.22E-29
THYM	IUPHAR	DHX9	PIKFYVE	0.805432377	4.93E-29
THYM	IUPHAR	DHX9	PIK3R4	0.806697064	3.47E-29
THYM	IUPHAR	DHX9	SIRT1	0.808719423	1.97E-29
THYM	IUPHAR	DHX9	OXSR1	0.811622169	8.63E-30
THYM	IUPHAR	DHX9	PI4K2B	0.813500989	5.02E-30
THYM	IUPHAR	DHX9	SETD2	0.813520064	5.00E-30
THYM	IUPHAR	DHX9	SENP1	0.815851896	2.53E-30
THYM	IUPHAR	DHX9	ADAM10	0.821114723	5.25E-31
THYM	IUPHAR	DHX9	TNKS2	0.822333515	3.62E-31
THYM	IUPHAR	DHX9	SCYL2	0.824181046	2.05E-31
THYM	IUPHAR	DHX9	DNMT1	0.832304818	1.55E-32
THYM	IUPHAR	DHX9	MAP3K7	0.834867309	6.68E-33
THYM	IUPHAR	DHX9	NR2C2	0.840232759	1.09E-33
THYM	IUPHAR	DHX9	SLC35A3	0.847503382	8.37E-35
THYM	IUPHAR	DHX9	PIP5K1A	0.84761582	8.03E-35
THYM	IUPHAR	DHX9	TRRAP	0.847959403	7.09E-35
THYM	IUPHAR	DHX9	PRMT3	0.851051499	2.28E-35
THYM	IUPHAR	DHX9	SLC35E3	0.878521672	2.60E-40
THYM	IUPHAR	DHX9	MAPK8	0.898413753	1.05E-44
THYM	IUPHAR	DHX9	CDK8	0.908754961	2.29E-47
THYM	IUPHAR	DHX9	TOP1	0.912850694	1.65E-48
THYM	Kinase	DHX9	BRD3	0.802381302	1.14E-28
THYM	Kinase	DHX9	ATR	0.80258855	1.07E-28
THYM	Kinase	DHX9	NEK7	0.804589548	6.22E-29
THYM	Kinase	DHX9	PIK3R4	0.806697064	3.47E-29
THYM	Kinase	DHX9	OXSR1	0.811622169	8.63E-30
THYM	Kinase	DHX9	SCYL2	0.824181046	2.05E-31
THYM	Kinase	DHX9	MAP3K7	0.834867309	6.68E-33
THYM	Kinase	DHX9	TRRAP	0.847959403	7.09E-35
THYM	Kinase	DHX9	MAPK8	0.898413753	1.05E-44
THYM	Kinase	DHX9	CDK8	0.908754961	2.29E-47
THYM	TF	DHX9	TFDP1	0.801286275	1.53E-28
THYM	TF	DHX9	ZFX	0.803435988	8.53E-29
THYM	TF	DHX9	ZFP91	0.807219356	3.00E-29
THYM	TF	DHX9	ZFP30	0.807711	2.61E-29
THYM	TF	DHX9	ZNF670	0.810599759	1.16E-29
THYM	TF	DHX9	TOPORS	0.812546213	6.62E-30
THYM	TF	DHX9	ZNF184	0.814042058	4.29E-30
THYM	TF	DHX9	ATF6B	0.816002249	2.42E-30
THYM	TF	DHX9	ZNF765	0.81703012	1.79E-30
THYM	TF	DHX9	RLF	0.820960841	5.50E-31
THYM	TF	DHX9	ZBTB39	0.822230743	3.74E-31
THYM	TF	DHX9	GLYR1	0.824745469	1.72E-31
THYM	TF	DHX9	DNMT1	0.832304818	1.55E-32
THYM	TF	DHX9	SP4	0.833061055	1.21E-32
THYM	TF	DHX9	SP2	0.833645254	1.00E-32
THYM	TF	DHX9	ZNF225	0.835875177	4.77E-33
THYM	TF	DHX9	NR2C2	0.840232759	1.09E-33
THYM	TF	DHX9	YY1	0.84295218	4.24E-34
THYM	TF	DHX9	CDC5L	0.843030244	4.12E-34
THYM	TF	DHX9	ZNF227	0.843433925	3.58E-34
THYM	TF	DHX9	ZNF217	0.850130911	3.20E-35
THYM	TF	DHX9	PRMT3	0.851051499	2.28E-35
THYM	TF	DHX9	ZNF146	0.851673123	1.81E-35
THYM	TF	DHX9	ZNF627	0.853011282	1.09E-35
THYM	TF	DHX9	ZNF567	0.857776983	1.76E-36
THYM	TF	DHX9	ZNF776	0.858364208	1.40E-36
THYM	TF	DHX9	SP3	0.861698817	3.71E-37
THYM	TF	DHX9	DR1	0.866906238	4.36E-38
THYM	TF	DHX9	ELF1	0.867019656	4.15E-38
THYM	TF	DHX9	ATF1	0.868520061	2.20E-38
THYM	TF	DHX9	ADNP	0.868522368	2.20E-38
THYM	TF	DHX9	ZNF430	0.870129199	1.11E-38
THYM	TF	DHX9	ZNF468	0.882455622	4.08E-41
THYM	TF	DHX9	ZNF28	0.89064601	6.88E-43
THYM	TF	DHX9	ZNF689	0.898368928	1.08E-44
THYM	TSG	DHX9	TP53BP1	0.800154058	2.07E-28
THYM	TSG	DHX9	ATR	0.80258855	1.07E-28
THYM	TSG	DHX9	TP53BP2	0.807712515	2.61E-29
THYM	TSG	DHX9	RANBP9	0.808574625	2.05E-29
THYM	TSG	DHX9	SIRT1	0.808719423	1.97E-29
THYM	TSG	DHX9	CCAR1	0.810210668	1.29E-29
THYM	TSG	DHX9	TOPORS	0.812546213	6.62E-30
THYM	TSG	DHX9	LIN9	0.813308717	5.31E-30
THYM	TSG	DHX9	SETD2	0.813520064	5.00E-30
THYM	TSG	DHX9	INTS6	0.814518652	3.74E-30
THYM	TSG	DHX9	CDC73	0.815048411	3.20E-30
THYM	TSG	DHX9	HACE1	0.82302891	2.92E-31
THYM	TSG	DHX9	HLTF	0.823130747	2.83E-31
THYM	TSG	DHX9	RB1	0.827415815	7.45E-32
THYM	TSG	DHX9	DNMT1	0.832304818	1.55E-32
THYM	TSG	DHX9	CUL2	0.83378848	9.54E-33
THYM	TSG	DHX9	BRCA2	0.840079448	1.15E-33
THYM	TSG	DHX9	NR2C2	0.840232759	1.09E-33
THYM	TSG	DHX9	NUP98	0.841204334	7.79E-34
THYM	TSG	DHX9	IGF2R	0.841807157	6.32E-34
THYM	TSG	DHX9	ANAPC1	0.844337417	2.60E-34
THYM	TSG	DHX9	EAF1	0.846369401	1.26E-34
THYM	TSG	DHX9	VHL	0.858681172	1.23E-36
UCEC	Cell metabolism gene	DHX9	CDK8	0.816331693	2.51E-49
UCEC	Cell metabolism gene	DHX9	RQCD1	0.826522713	1.48E-51
UCEC	CGC	DHX9	FUBP1	0.828623032	4.92E-52
UCEC	Epifactor	DHX9	RNF168	0.80962853	6.21E-48
UCEC	Epifactor	DHX9	RBBP5	0.811618778	2.43E-48
UCEC	Epifactor	DHX9	RBBP4	0.823485831	7.07E-51
UCEC	IUPHAR	DHX9	SLC30A6	0.815573931	3.64E-49
UCEC	IUPHAR	DHX9	CDK8	0.816331693	2.51E-49
UCEC	Kinase	DHX9	CDK8	0.816331693	2.51E-49
UCEC	TF	DHX9	ZNF689	0.814069618	7.53E-49
UCS	Cell metabolism gene	DHX9	PGM2	0.801183367	1.57E-28
UCS	Cell metabolism gene	DHX9	GLS	0.80289431	9.89E-29
UCS	Cell metabolism gene	DHX9	MANEA	0.80357147	8.22E-29
UCS	Cell metabolism gene	DHX9	PIKFYVE	0.805432377	4.93E-29
UCS	Cell metabolism gene	DHX9	PGAM4	0.806456971	3.71E-29
UCS	Cell metabolism gene	DHX9	PIK3R4	0.806697064	3.47E-29
UCS	Cell metabolism gene	DHX9	PNPLA8	0.807459292	2.80E-29
UCS	Cell metabolism gene	DHX9	GLUD2	0.807574197	2.72E-29
UCS	Cell metabolism gene	DHX9	SEC24B	0.811628884	8.62E-30
UCS	Cell metabolism gene	DHX9	PI4K2B	0.813500989	5.02E-30
UCS	Cell metabolism gene	DHX9	DLAT	0.813834572	4.56E-30
UCS	Cell metabolism gene	DHX9	B3GNT2	0.815718731	2.63E-30
UCS	Cell metabolism gene	DHX9	ACAD8	0.820042158	7.26E-31
UCS	Cell metabolism gene	DHX9	TRMT11	0.821064805	5.33E-31
UCS	Cell metabolism gene	DHX9	DNMT1	0.832304818	1.55E-32
UCS	Cell metabolism gene	DHX9	FBXW2	0.837489585	2.78E-33
UCS	Cell metabolism gene	DHX9	MUT	0.837616123	2.66E-33
UCS	Cell metabolism gene	DHX9	BCKDHB	0.838403017	2.04E-33
UCS	Cell metabolism gene	DHX9	MTM1	0.839590644	1.36E-33
UCS	Cell metabolism gene	DHX9	MAT2B	0.842999468	4.17E-34
UCS	Cell metabolism gene	DHX9	PIP5K1A	0.84761582	8.03E-35
UCS	Cell metabolism gene	DHX9	NUP153	0.851369406	2.02E-35
UCS	Cell metabolism gene	DHX9	NUP107	0.855740366	3.87E-36
UCS	Cell metabolism gene	DHX9	SRP54	0.856819375	2.55E-36
UCS	Cell metabolism gene	DHX9	ACADM	0.86551398	7.79E-38
UCS	Cell metabolism gene	DHX9	NUP205	0.887670841	3.14E-42
UCS	Cell metabolism gene	DHX9	CDK8	0.908754961	2.29E-47
UCS	Cell metabolism gene	DHX9	XRN2	0.914345096	6.11E-49
UCS	Cell metabolism gene	DHX9	MED17	0.918261123	4.15E-50
UCS	Cell metabolism gene	DHX9	TGS1	0.928091992	2.56E-53
UCS	Cell metabolism gene	DHX9	POLR2B	0.930308451	4.18E-54
UCS	Cell metabolism gene	DHX9	RQCD1	0.945491504	2.60E-60
UCS	CGC	DHX9	BRD3	0.802381302	1.14E-28
UCS	CGC	DHX9	ATR	0.80258855	1.07E-28
UCS	CGC	DHX9	ZCCHC8	0.809118242	1.76E-29
UCS	CGC	DHX9	ERCC3	0.81186738	8.05E-30
UCS	CGC	DHX9	SETD2	0.813520064	5.00E-30
UCS	CGC	DHX9	THRAP3	0.814807535	3.43E-30
UCS	CGC	DHX9	CDC73	0.815048411	3.20E-30
UCS	CGC	DHX9	RB1	0.827415815	7.45E-32
UCS	CGC	DHX9	BRCA2	0.840079448	1.15E-33
UCS	CGC	DHX9	NUP98	0.841204334	7.79E-34
UCS	CGC	DHX9	RAD21	0.845068517	2.01E-34
UCS	CGC	DHX9	TRRAP	0.847959403	7.09E-35
UCS	CGC	DHX9	STAG1	0.849109961	4.66E-35
UCS	CGC	DHX9	VHL	0.858681172	1.23E-36
UCS	CGC	DHX9	BCOR	0.864067406	1.42E-37
UCS	CGC	DHX9	ATF1	0.868520061	2.20E-38
UCS	CGC	DHX9	MLLT10	0.870649641	8.83E-39
UCS	CGC	DHX9	FUBP1	0.906170105	1.13E-46
UCS	CGC	DHX9	TOP1	0.912850694	1.65E-48
UCS	Epifactor	DHX9	TP53BP1	0.800154058	2.07E-28
UCS	Epifactor	DHX9	TFDP1	0.801286275	1.53E-28
UCS	Epifactor	DHX9	BRD3	0.802381302	1.14E-28
UCS	Epifactor	DHX9	PHF8	0.802545178	1.09E-28
UCS	Epifactor	DHX9	ATR	0.80258855	1.07E-28
UCS	Epifactor	DHX9	SIRT1	0.808719423	1.97E-29
UCS	Epifactor	DHX9	PHF20L1	0.810315556	1.25E-29
UCS	Epifactor	DHX9	TAF4	0.812565773	6.58E-30
UCS	Epifactor	DHX9	SETD2	0.813520064	5.00E-30
UCS	Epifactor	DHX9	CDC73	0.815048411	3.20E-30
UCS	Epifactor	DHX9	SENP1	0.815851896	2.53E-30
UCS	Epifactor	DHX9	C11orf30	0.816082145	2.36E-30
UCS	Epifactor	DHX9	ACTR6	0.82206636	3.93E-31
UCS	Epifactor	DHX9	HLTF	0.823130747	2.83E-31
UCS	Epifactor	DHX9	ATXN7L3	0.824738633	1.72E-31
UCS	Epifactor	DHX9	GLYR1	0.824745469	1.72E-31
UCS	Epifactor	DHX9	DDX21	0.825192338	1.50E-31
UCS	Epifactor	DHX9	RB1	0.827415815	7.45E-32
UCS	Epifactor	DHX9	SMEK2	0.827728177	6.75E-32
UCS	Epifactor	DHX9	DNMT1	0.832304818	1.55E-32
UCS	Epifactor	DHX9	CUL2	0.83378848	9.54E-33
UCS	Epifactor	DHX9	MAP3K7	0.834867309	6.68E-33
UCS	Epifactor	DHX9	RCOR1	0.836892973	3.39E-33
UCS	Epifactor	DHX9	BRCA2	0.840079448	1.15E-33
UCS	Epifactor	DHX9	YY1	0.84295218	4.24E-34
UCS	Epifactor	DHX9	TRRAP	0.847959403	7.09E-35
UCS	Epifactor	DHX9	ZNF217	0.850130911	3.20E-35
UCS	Epifactor	DHX9	RBBP5	0.861970271	3.32E-37
UCS	Epifactor	DHX9	BCOR	0.864067406	1.42E-37
UCS	Epifactor	DHX9	DR1	0.866906238	4.36E-38
UCS	Epifactor	DHX9	ADNP	0.868522368	2.20E-38
UCS	Epifactor	DHX9	SMARCA5	0.869158455	1.68E-38
UCS	Epifactor	DHX9	EPC1	0.87031019	1.02E-38
UCS	Epifactor	DHX9	MLLT10	0.870649641	8.83E-39
UCS	Epifactor	DHX9	UCHL5	0.872279825	4.34E-39
UCS	Epifactor	DHX9	TADA2A	0.875543661	1.02E-39
UCS	Epifactor	DHX9	CTR9	0.877119307	4.96E-40
UCS	Epifactor	DHX9	TADA1	0.878789456	2.30E-40
UCS	Epifactor	DHX9	ZRANB3	0.883680522	2.26E-41
UCS	Epifactor	DHX9	SMARCAD1	0.886336961	6.13E-42
UCS	Epifactor	DHX9	RBBP4	0.89227697	2.94E-43
UCS	Epifactor	DHX9	TAF2	0.906470225	9.42E-47
UCS	IUPHAR	DHX9	BRD3	0.802381302	1.14E-28
UCS	IUPHAR	DHX9	PHF8	0.802545178	1.09E-28
UCS	IUPHAR	DHX9	ATR	0.80258855	1.07E-28
UCS	IUPHAR	DHX9	GLS	0.80289431	9.89E-29
UCS	IUPHAR	DHX9	NEK7	0.804589548	6.22E-29
UCS	IUPHAR	DHX9	PIKFYVE	0.805432377	4.93E-29
UCS	IUPHAR	DHX9	PIK3R4	0.806697064	3.47E-29
UCS	IUPHAR	DHX9	SIRT1	0.808719423	1.97E-29
UCS	IUPHAR	DHX9	OXSR1	0.811622169	8.63E-30
UCS	IUPHAR	DHX9	PI4K2B	0.813500989	5.02E-30
UCS	IUPHAR	DHX9	SETD2	0.813520064	5.00E-30
UCS	IUPHAR	DHX9	SENP1	0.815851896	2.53E-30
UCS	IUPHAR	DHX9	ADAM10	0.821114723	5.25E-31
UCS	IUPHAR	DHX9	TNKS2	0.822333515	3.62E-31
UCS	IUPHAR	DHX9	SCYL2	0.824181046	2.05E-31
UCS	IUPHAR	DHX9	DNMT1	0.832304818	1.55E-32
UCS	IUPHAR	DHX9	MAP3K7	0.834867309	6.68E-33
UCS	IUPHAR	DHX9	NR2C2	0.840232759	1.09E-33
UCS	IUPHAR	DHX9	SLC35A3	0.847503382	8.37E-35
UCS	IUPHAR	DHX9	PIP5K1A	0.84761582	8.03E-35
UCS	IUPHAR	DHX9	TRRAP	0.847959403	7.09E-35
UCS	IUPHAR	DHX9	PRMT3	0.851051499	2.28E-35
UCS	IUPHAR	DHX9	SLC35E3	0.878521672	2.60E-40
UCS	IUPHAR	DHX9	MAPK8	0.898413753	1.05E-44
UCS	IUPHAR	DHX9	CDK8	0.908754961	2.29E-47
UCS	IUPHAR	DHX9	TOP1	0.912850694	1.65E-48
UCS	Kinase	DHX9	BRD3	0.802381302	1.14E-28
UCS	Kinase	DHX9	ATR	0.80258855	1.07E-28
UCS	Kinase	DHX9	NEK7	0.804589548	6.22E-29
UCS	Kinase	DHX9	PIK3R4	0.806697064	3.47E-29
UCS	Kinase	DHX9	OXSR1	0.811622169	8.63E-30
UCS	Kinase	DHX9	SCYL2	0.824181046	2.05E-31
UCS	Kinase	DHX9	MAP3K7	0.834867309	6.68E-33
UCS	Kinase	DHX9	TRRAP	0.847959403	7.09E-35
UCS	Kinase	DHX9	MAPK8	0.898413753	1.05E-44
UCS	Kinase	DHX9	CDK8	0.908754961	2.29E-47
UCS	TF	DHX9	TFDP1	0.801286275	1.53E-28
UCS	TF	DHX9	ZFX	0.803435988	8.53E-29
UCS	TF	DHX9	ZFP91	0.807219356	3.00E-29
UCS	TF	DHX9	ZFP30	0.807711	2.61E-29
UCS	TF	DHX9	ZNF670	0.810599759	1.16E-29
UCS	TF	DHX9	TOPORS	0.812546213	6.62E-30
UCS	TF	DHX9	ZNF184	0.814042058	4.29E-30
UCS	TF	DHX9	ATF6B	0.816002249	2.42E-30
UCS	TF	DHX9	ZNF765	0.81703012	1.79E-30
UCS	TF	DHX9	RLF	0.820960841	5.50E-31
UCS	TF	DHX9	ZBTB39	0.822230743	3.74E-31
UCS	TF	DHX9	GLYR1	0.824745469	1.72E-31
UCS	TF	DHX9	DNMT1	0.832304818	1.55E-32
UCS	TF	DHX9	SP4	0.833061055	1.21E-32
UCS	TF	DHX9	SP2	0.833645254	1.00E-32
UCS	TF	DHX9	ZNF225	0.835875177	4.77E-33
UCS	TF	DHX9	NR2C2	0.840232759	1.09E-33
UCS	TF	DHX9	YY1	0.84295218	4.24E-34
UCS	TF	DHX9	CDC5L	0.843030244	4.12E-34
UCS	TF	DHX9	ZNF227	0.843433925	3.58E-34
UCS	TF	DHX9	ZNF217	0.850130911	3.20E-35
UCS	TF	DHX9	PRMT3	0.851051499	2.28E-35
UCS	TF	DHX9	ZNF146	0.851673123	1.81E-35
UCS	TF	DHX9	ZNF627	0.853011282	1.09E-35
UCS	TF	DHX9	ZNF567	0.857776983	1.76E-36
UCS	TF	DHX9	ZNF776	0.858364208	1.40E-36
UCS	TF	DHX9	SP3	0.861698817	3.71E-37
UCS	TF	DHX9	DR1	0.866906238	4.36E-38
UCS	TF	DHX9	ELF1	0.867019656	4.15E-38
UCS	TF	DHX9	ATF1	0.868520061	2.20E-38
UCS	TF	DHX9	ADNP	0.868522368	2.20E-38
UCS	TF	DHX9	ZNF430	0.870129199	1.11E-38
UCS	TF	DHX9	ZNF468	0.882455622	4.08E-41
UCS	TF	DHX9	ZNF28	0.89064601	6.88E-43
UCS	TF	DHX9	ZNF689	0.898368928	1.08E-44
UCS	TSG	DHX9	TP53BP1	0.800154058	2.07E-28
UCS	TSG	DHX9	ATR	0.80258855	1.07E-28
UCS	TSG	DHX9	TP53BP2	0.807712515	2.61E-29
UCS	TSG	DHX9	RANBP9	0.808574625	2.05E-29
UCS	TSG	DHX9	SIRT1	0.808719423	1.97E-29
UCS	TSG	DHX9	CCAR1	0.810210668	1.29E-29
UCS	TSG	DHX9	TOPORS	0.812546213	6.62E-30
UCS	TSG	DHX9	LIN9	0.813308717	5.31E-30
UCS	TSG	DHX9	SETD2	0.813520064	5.00E-30
UCS	TSG	DHX9	INTS6	0.814518652	3.74E-30
UCS	TSG	DHX9	CDC73	0.815048411	3.20E-30
UCS	TSG	DHX9	HACE1	0.82302891	2.92E-31
UCS	TSG	DHX9	HLTF	0.823130747	2.83E-31
UCS	TSG	DHX9	RB1	0.827415815	7.45E-32
UCS	TSG	DHX9	DNMT1	0.832304818	1.55E-32
UCS	TSG	DHX9	CUL2	0.83378848	9.54E-33
UCS	TSG	DHX9	BRCA2	0.840079448	1.15E-33
UCS	TSG	DHX9	NR2C2	0.840232759	1.09E-33
UCS	TSG	DHX9	NUP98	0.841204334	7.79E-34
UCS	TSG	DHX9	IGF2R	0.841807157	6.32E-34
UCS	TSG	DHX9	ANAPC1	0.844337417	2.60E-34
UCS	TSG	DHX9	EAF1	0.846369401	1.26E-34
UCS	TSG	DHX9	VHL	0.858681172	1.23E-36
UVM	Cell metabolism gene	DHX9	DLAT	0.801423959	4.32E-19
UVM	Cell metabolism gene	DHX9	MED1	0.804452673	2.53E-19
UVM	Cell metabolism gene	DHX9	HIF1A	0.812453924	5.83E-20
UVM	Cell metabolism gene	DHX9	NUP133	0.815085746	3.54E-20
UVM	Cell metabolism gene	DHX9	PAFAH1B2	0.84146608	1.49E-22
UVM	Cell metabolism gene	DHX9	PIK3C3	0.842002048	1.32E-22
UVM	Cell metabolism gene	DHX9	NCOA2	0.85394853	7.81E-24
UVM	Cell metabolism gene	DHX9	NUP155	0.874836993	2.87E-26
UVM	CGC	DHX9	KDM5A	0.806205744	1.84E-19
UVM	CGC	DHX9	HIF1A	0.812453924	5.83E-20
UVM	CGC	DHX9	IL6ST	0.813143776	5.12E-20
UVM	CGC	DHX9	BIRC6	0.821529752	1.01E-20
UVM	CGC	DHX9	CLTC	0.828283899	2.58E-21
UVM	CGC	DHX9	PAFAH1B2	0.84146608	1.49E-22
UVM	CGC	DHX9	STRN	0.847779096	3.47E-23
UVM	CGC	DHX9	NCOA2	0.85394853	7.81E-24
UVM	CGC	DHX9	ASXL2	0.863039956	7.63E-25
UVM	Epifactor	DHX9	EPC1	0.800998812	4.66E-19
UVM	Epifactor	DHX9	KDM5A	0.806205744	1.84E-19
UVM	Epifactor	DHX9	DDX21	0.833702828	8.23E-22
UVM	Epifactor	DHX9	RCOR1	0.835907899	5.11E-22
UVM	Epifactor	DHX9	USP12	0.853419759	8.90E-24
UVM	Epifactor	DHX9	NCOA2	0.85394853	7.81E-24
UVM	Epifactor	DHX9	ASXL2	0.863039956	7.63E-25
UVM	Epifactor	DHX9	RBBP5	0.863210422	7.29E-25
UVM	IUPHAR	DHX9	HIPK3	0.805001015	2.29E-19
UVM	IUPHAR	DHX9	KDM5A	0.806205744	1.84E-19
UVM	IUPHAR	DHX9	ADAM17	0.808179605	1.29E-19
UVM	IUPHAR	DHX9	MAPK8	0.812954933	5.31E-20
UVM	IUPHAR	DHX9	IL6ST	0.813143776	5.12E-20
UVM	IUPHAR	DHX9	DPP8	0.815911907	3.03E-20
UVM	IUPHAR	DHX9	SLC30A6	0.818097044	1.99E-20
UVM	IUPHAR	DHX9	BIRC6	0.821529752	1.01E-20
UVM	IUPHAR	DHX9	TAOK1	0.835777021	5.26E-22
UVM	IUPHAR	DHX9	PIK3C3	0.842002048	1.32E-22
UVM	IUPHAR	DHX9	NCOA2	0.85394853	7.81E-24
UVM	IUPHAR	DHX9	IDE	0.858549684	2.46E-24
UVM	Kinase	DHX9	HIPK3	0.805001015	2.29E-19
UVM	Kinase	DHX9	MAPK8	0.812954933	5.31E-20
UVM	Kinase	DHX9	TAOK1	0.835777021	5.26E-22
UVM	TF	DHX9	HIF1A	0.812453924	5.83E-20
UVM	TF	DHX9	ADNP2	0.813951119	4.40E-20
UVM	TF	DHX9	ZNF281	0.824628662	5.44E-21
UVM	TF	DHX9	SON	0.827377194	3.11E-21
UVM	TF	DHX9	NCOA2	0.85394853	7.81E-24
UVM	TF	DHX9	ETV3	0.867733987	2.15E-25
UVM	TF	DHX9	ATF6	0.881470236	3.91E-27
UVM	TF	DHX9	ZFP91	0.884315509	1.60E-27
UVM	TSG	DHX9	KDM5A	0.806205744	1.84E-19
UVM	TSG	DHX9	HIF1A	0.812453924	5.83E-20
UVM	TSG	DHX9	RNF111	0.819273293	1.58E-20
UVM	TSG	DHX9	TP53BP2	0.822822371	7.83E-21
UVM	TSG	DHX9	ANAPC1	0.823154432	7.32E-21
UVM	TSG	DHX9	USP12	0.853419759	8.90E-24

Top

Protein structure

Protein 3D structure
Visit iCn3D.

Top

Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
COAD	DHX9	HNRNPU	-3.25414367586013	0.000109195709228516
LIHC	DHX9	EWSR1	-1.00920017153145	0.000263325268073385
PRAD	DHX9	ILF3	-1.66399002266096	0.000376184722398862
KICH	DHX9	HNRNPU	1.45270865891102	0.000376403331756592
PRAD	DHX9	HNRNPU	-3.59255010200453	0.00074054058184854
KICH	DHX9	EWSR1	1.22318794588959	0.00202512741088867
KICH	DHX9	ILF3	-1.08690451087032	0.00308787822723389
CHOL	DHX9	PABPC1	-4.56272528815353	0.00390625
LIHC	DHX9	BRCA1	-1.00722832369288	0.00593802028362182
PRAD	DHX9	DICER1	1.54768558737379	0.0130781232419534
BLCA	DHX9	PABPC1	1.31485302792746	0.0180816650390625
ESCA	DHX9	EWSR1	-3.15606244879581	0.0185546875
UCEC	DHX9	BRCA1	-6.22851128981174	0.03125
BLCA	DHX9	EWSR1	1.34714628964121	0.0445594787597656
UCEC	DHX9	ILF3	1.60315027085684	0.046875
KIRC	DHX9	BRCA1	-1.01267158046895	1.19932271980764e-10
LUAD	DHX9	BRCA1	-6.14620540426686	1.6265691620167e-09
STAD	DHX9	HNRNPU	-1.26566952320815	2.26888805627823e-05
LIHC	DHX9	HNRNPU	-1.06098658215773	2.35319665208461e-06
LIHC	DHX9	PABPC1	-1.72076961362188	2.98009622125841e-06
BRCA	DHX9	ILF3	-1.25150240382867	3.29730506460964e-06
BRCA	DHX9	YBX1	1.10467241966451	4.8741280959683e-05
KICH	DHX9	EIF4E	1.61675210562671	6.55651092529297e-06
STAD	DHX9	ILF3	-2.09020109679651	7.8696757555008e-08
KICH	DHX9	YBX1	1.86923259160472	8.16583633422851e-06
PRAD	DHX9	PABPC1	-2.10200318363476	8.55379952759014e-07
STAD	DHX9	EWSR1	-1.73111038863938	9.0546440333128e-05
KIRP	DHX9	BRCA1	-1.8514057643987	9.31322574615479e-10

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with DHX9

CNBP, ARHGDIA, LYAR, RELA, PRMT1, TOP2A, MBD2, BRCA1, JUN, AKAP8L, NXF1, KHDRBS1, SMN1, TBP, GTF2B, GEMIN2, DDX20, GEMIN4, HDLBP, XRCC5, XRCC6, MEPCE, SND1, EWSR1, ACTA1, HNRNPC, H2AFX, PRKDC, PHF1, Ube2i, Ilf3, Pias2, UBE2I, ABCB1, WRN, UBC, Mapk13, DGCR8, HDAC5, NOP56, TOP1, Nhp2l1, Ybx1, EBNA-LP, EIF2AK2, PCNA, SMARCAD1, RAD21, HDGF, MBNL1, SF3A2, HNRNPA1, POLR2A, ACTB, ZMAT3, HEXIM1, DICER1, AGO2, gag, POLD1, CUL3, CUL4A, CUL4B, CUL5, CUL2, CDK2, CUL1, COPS5, DCUN1D1, CAND1, NEDD8, RN7SK, BIRC2, GRK5, PRPF8, SSRP1, SRSF1, EFTUD2, SRSF7, ILF3, U2AF1, SRSF3, RBM8A, HNRNPF, RPL31, ILF2, DDX17, RPL6, RPL37A, RPS6, RPS26, RPS5, RPL5, RPS24, RPL9, ACIN1, RPS11, SRRM2, SRRT, SART1, RPS14, USP39, EIF6, RALY, RPSA, LBR, HIST1H2BB, SON, MVP, EMD, THRAP3, NFIA, TMEM126B, PSEN1, RANBP2, NDUFAF4, VTN, KIF5B, TOMM70A, TIMM9, PPIB, CRK, TRIM55, RHOT2, SUGP2, RAB5B, RRS1, UTP14A, PTRF, GLYR1, HELQ, ESR1, SMURF1, FN1, VCAM1, DDX5, HNRNPK, RBM4, TP63, IL7R, vif, NCL, ADAR, HNRNPU, CTNNB1, PAN2, FBXW4, FBXO46, SRPK3, YWHAQ, FBXO6, TARDBP, PRPF40A, APBB1, C14orf166, RTCB, NELFB, YBX3, DDX1, ABCF1, EIF2B2, EIF2B3, FLII, HNRNPA0, LRRFIP1, MAP2, PSMD8, HNRNPM, IGF2BP3, MAP7, MRE11A, NMT1, PSMD13, QARS, RFC4, RPL26L1, RPL27A, RPL27, rev, RPA1, RPA2, RPA3, WWOX, LGR4, IVNS1ABP, STAU1, MDM2, AURKA, CEP250, SART3, PA2G4, FBXW11, MOV10, CUL7, OBSL1, CCDC8, EZH2, SUZ12, EED, RNF2, L1TD1, PRMT8, RPS6KB2, NTRK1, ABCD3, ALYREF, CDC5L, HSPA5, TXNL1, EIF1, EIF1B, HNRNPR, HSPA4L, NAA15, SNRPD1, SPTAN1, TMOD2, TMOD3, USP7, SCARNA22, PPP1CB, RPL10, MATR3, THOC1, THOC2, THOC7, Ppp1cb, Rpl35, Taf15, Hnrnpa3, Fus, MACROD1, MCM2, MCM5, SNW1, U2AF2, EGFR, WWP2, ZNF746, OCRL, CYLD, INO80B, TRIM25, RNF168, MTF1, FBXO7, MEX3C, TMPO, API5, WDR77, DIMT1, HSPA8, KRAS, PCBP1, BMP4, MAP2K3, MATN2, PPIE, TBX3, TRIP4, AAR2, PIH1D1, TNIP2, CHD3, CHD4, LARP7, RNF4, SPDL1, RIOK1, RUNX1, RNF123, PPT1, SNAI1, AGR2, RECQL4, DCPS, REST, MYC, CDK9, WDR76, HIST1H4A, HIST1H2AB, GRWD1, KIAA1429, METTL14, PSME3, USP18, RC3H1, RC3H2, ATG16L1, ZBTB7A, PHB, RBX1, TMEM41B, CHEK2, USP14, NR2C2, UBQLN2, PPARG, CTCF, VRK1, PARS2, DLAT, HSD17B4, LRPPRC, PDHX, RARS, PSMD14, SNRNP70, FUS, TAF15, SNRPC, ITFG1, ARAF, BIRC3, NFX1, BRD7, TP53, SOX2, TRIM28, GRIA4, CMTR1, OTUD3, ARIH2, PLEKHA4, MAGEA3, PINK1, YAP1, TFCP2, FANCD2, NGB, PTEN, LINC01554, ZC3H18, PDPK1, RAB5A, KCNV1, AKAP9, ZBED4, ATP5O, INPP5A, PIK3R6, GBP6, GGH, UBN1, DNMT3B, LINC00173, RTTN, FRAS1, TAAR3, PMEPA1, ANKRD55, M, nsp4, nsp6, ELAVL1, NEK4, LRRC31, DUX4, CIT, ANLN, AURKB, CHMP4B, ECT2, KIF14, KIF20A, KIF23, PRC1, GRSF1, LRRC59, NDN, NONO, BIN1, SFPQ, MAFB, BRD4, NUPR1, RBM45, CIC, Apc2, RBM39, FBP1, LGALS9, YWHAE, IFI16, N, FMR1, USP10, NEIL3, vpr, RIN3, DNAJC15, DNAJC2, DNAJC8, KDF1, OGT, DDRGK1, SPOP, AR, ATG5, ISG15, PARK2, UFL1, LINC00152, DDX39B, TRIM37, FZR1, WDR5, NUDCD2, BGLT3, ZBTB2, FAM120A, UTP23, MAGEB2, RRP9, SPRTN, USP11, BTF3, SLFN11, EP300, FBXW7, CUL9, NLRP7, AGO1, RCHY1, DIDO1, FBXL6, CCNF, MAP1LC3B, SQSTM1, TRIM71, SIRT6, RB1CC1, MAGEL2, ZEB1, MARCH6,

Top

Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
DHX9	chr1	182821485	G	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
DHX9	chr1	182827297	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001619\|non-coding_transcript_variant,SO:0001819\|synonymous_variant	SO:0001619\|non-coding_transcript_variant,SO:0001819\|synonymous_variant
DHX9	chr1	182850399	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001619\|non-coding_transcript_variant,SO:0001819\|synonymous_variant	SO:0001619\|non-coding_transcript_variant,SO:0001819\|synonymous_variant
DHX9	chr1	182850483	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001619\|non-coding_transcript_variant,SO:0001819\|synonymous_variant	SO:0001619\|non-coding_transcript_variant,SO:0001819\|synonymous_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
DHX9	BLCA	chr1	182812436	182812436	T	G	Missense_Mutation	p.V40G	24
DHX9	UCEC	chr1	182852658	182852658	C	T	Nonsense_Mutation	p.R1050*	6
DHX9	SKCM	chr1	182853892	182853892	C	T	Silent	p.I1135I	4
DHX9	ESCA	chr1	182852698	182852698	C	-	Frame_Shift_Del	p.T1063fs	4
DHX9	KIRP	chr1	182856426	182856426	G	C	Missense_Mutation	p.G1224R	4
DHX9	KIRP	chr1	182850707	182850707	A	G	Missense_Mutation	p.M947V	4
DHX9	UCS	chr1	182848417	182848417	G	A	Missense_Mutation	p.R795Q	3
DHX9	HNSC	chr1	182835672	182835672	G	A	Missense_Mutation	p.E476K	3
DHX9	UCS	chr1	182850453	182850453	C	T	Silent	p.F893F	3
DHX9	PAAD	chr1	182846018	182846018	T	G	Silent	p.V726V	3
DHX9	HNSC	chr1	182853912	182853912	C	T	Missense_Mutation	p.S1142L	3
DHX9	UCS	chr1	182829308	182829308	G	T	Missense_Mutation	p.V441L	3
DHX9	LIHC	chr1	182823304	182823304	A	G	Missense_Mutation	p.D206G	3
DHX9	UCEC	chr1	182845332	182845333	-	T	Frame_Shift_Ins	p.V655fs	3
DHX9	ESCA	chr1	182856565	182856565	A	T	Missense_Mutation	p.Y1270F	3
DHX9	CHOL	chr1	182846025	182846025	A	G	Missense_Mutation		3
DHX9	LIHC	chr1	182852382	182852382	A	T	Missense_Mutation	p.E1008V	3
DHX9	PAAD	chr1	182850546	182850546	C	T	Silent	p.A924A	3
DHX9	CHOL	chr1	182846025	182846025	A	G	Missense_Mutation	p.I729V	3
DHX9	PAAD	chr1	182852411	182852411	C	T	Missense_Mutation	p.R1018C	3
DHX9	STAD	chr1	182856513	182856514	-	G	Frame_Shift_Ins	p.R1253fs	3
DHX9	BRCA	chr1	182853847	182853847	C	T	Silent	p.I1120	3
DHX9	STAD	chr1	182844070	182844070	A	G	Missense_Mutation	p.D599G	3
DHX9	CESC	chr1	182844020	182844020	C	T	Silent		3
DHX9	LIHC	chr1	182845333	182845333	T	-	Frame_Shift_Del	p.V655fs	3
DHX9	LUAD	chr1	182827319	182827319	C	T	Missense_Mutation	p.H252Y	3
DHX9	SKCM	chr1	182822450	182822450	C	T	Missense_Mutation	p.S125F	3
DHX9	UCEC	chr1	182823205	182823205	A	G	Missense_Mutation	p.H173R	3
DHX9	ESCA	chr1	182829167	182829167	G	A	Missense_Mutation	p.E394K	3
DHX9	CESC	chr1	182844012	182844012	C	G	Missense_Mutation		3
DHX9	SKCM	chr1	182852338	182852338	C	T	Silent	p.S993S	3
DHX9	ESCA	chr1	182850531	182850531	A	G	Silent		2
DHX9	KIRC	chr1	182841497	182841497	G	A	Missense_Mutation	p.R528H	2
DHX9	CESC	chr1	182845266	182845266	C	A	Missense_Mutation		2
DHX9	SKCM	chr1	182835669	182835669	T	C	Missense_Mutation	p.F475L	2
DHX9	PAAD	chr1	182850546	182850546	C	T	Silent		2
DHX9	SKCM	chr1	182847207	182847207	C	T	Silent	p.T750T	2
DHX9	ESCA	chr1	182844088	182844088	A	T	Missense_Mutation	p.D605V	2
DHX9	STAD	chr1	182849650	182849650	C	T	Missense_Mutation		2
DHX9	UCEC	chr1	182841507	182841507	T	C	Silent	p.V531	2
DHX9	BLCA	chr1	182822501	182822501	G	A	Missense_Mutation	p.G142E	2
DHX9	SKCM	chr1	182856422	182856422	C	T	Silent	p.S1222S	2
DHX9	PAAD	chr1	182852411	182852411	C	T	Missense_Mutation		2
DHX9	SKCM	chr1	182845266	182845266	C	T	Missense_Mutation	p.P633S	2
DHX9	LIHC	chr1	182836133	182836133	A	T	Silent		2
DHX9	STAD	chr1	182844052	182844052	A	G	Missense_Mutation		2
DHX9	STAD	chr1	182836115	182836115	A	G	Silent	p.L498L	2
DHX9	UCEC	chr1	182841526	182841526	C	T	Missense_Mutation	p.R538C	2
DHX9	ESCA	chr1	182856565	182856565	A	T	Missense_Mutation		2
DHX9	BLCA	chr1	182845653	182845653	C	T	Missense_Mutation	p.P701S	2
DHX9	SKCM	chr1	182845607	182845607	C	T	Silent	p.P685P	2
DHX9	BLCA	chr1	182845362	182845362	A	G	Missense_Mutation	p.T665A	2
DHX9	STAD	chr1	182853799	182853799	G	T	Silent	p.R1104R	2
DHX9	UCEC	chr1	182845357	182845357	T	G	Missense_Mutation	p.I663S	2
DHX9	ESCA	chr1	182829167	182829167	G	A	Missense_Mutation		2
DHX9	LUAD	chr1	182827742	182827742	C	G	Missense_Mutation	p.I289M	2
DHX9	BLCA	chr1	182841625	182841625	C	T	Nonsense_Mutation	p.Q571*	2
DHX9	SKCM	chr1	182845262	182845262	A	G	Silent	p.E631E	2
DHX9	LIHC	chr1	182848473	182848473	G	A	Missense_Mutation		2
DHX9	BRCA	chr1	182811768	182811768	A	G	Missense_Mutation	p.I23V	2
DHX9	UCEC	chr1	182845677	182845677	G	A	Splice_Site	e17+1	2
DHX9	UCS	chr1	182821465	182821465	T	G	Missense_Mutation	p.L117R	2
DHX9	SKCM	chr1	182827968	182827968	C	A	Missense_Mutation	p.P334H	2
DHX9	STAD	chr1	182844052	182844052	A	G	Missense_Mutation	p.K593R	2
DHX9	UCEC	chr1	182821399	182821399	C	A	Missense_Mutation	p.P95H	2
DHX9	LGG	chr1	182852725	182852725	C	T	Missense_Mutation	p.S1072F	2
DHX9	STAD	chr1	182847239	182847239	G	A	Missense_Mutation	p.R761Q	2
DHX9	UCEC	chr1	182850469	182850469	C	T	Missense_Mutation	p.R899W	2
DHX9	ESCA	chr1	182822528	182822528	G	T	Missense_Mutation	p.R151I	2
DHX9	HNSC	chr1	182827949	182827949	G	A	Missense_Mutation	p.G328S	2
DHX9	LIHC	chr1	182847265	182847265	C	G	Missense_Mutation		2
DHX9	BRCA	chr1	182849707	182849707	G	A	Missense_Mutation	p.R863H	2
DHX9	BLCA	chr1	182827713	182827713	C	G	Missense_Mutation		2
DHX9	STAD	chr1	182827950	182827950	G	A	Missense_Mutation	p.G328D	2
DHX9	UCEC	chr1	182827274	182827274	T	A	Missense_Mutation	p.L237M	2
DHX9	HNSC	chr1	182845596	182845596	C	G	Missense_Mutation	p.Q682E	2
DHX9	LIHC	chr1	182852766	182852766	G	A	Missense_Mutation		2
DHX9	COAD	chr1	182811720	182811720	T	G	Missense_Mutation	p.F7V	2
DHX9	LIHC	chr1	182848432	182848432	A	-	Frame_Shift_Del	p.E800fs	2
DHX9	STAD	chr1	182849650	182849650	C	T	Missense_Mutation	p.A844V	2
DHX9	UCEC	chr1	182827691	182827691	G	A	Silent	p.E272	2
DHX9	UCEC	chr1	182856295	182856295	A	G	Missense_Mutation	p.Y1180C	2
DHX9	ESCA	chr1	182844088	182844088	A	T	Missense_Mutation		2
DHX9	HNSC	chr1	182856371	182856371	C	A	Silent	p.S1205S	2
DHX9	LIHC	chr1	182852382	182852382	A	T	Missense_Mutation		2
DHX9	BLCA	chr1	182849729	182849729	G	-	Frame_Shift_Del		2
DHX9	LUAD	chr1	182850485	182850485	A	T	Missense_Mutation	p.H904L	2
DHX9	SARC	chr1	182856417	182856417	G	T	Missense_Mutation		2
DHX9	SKCM	chr1	182827877	182827877	C	T	Missense_Mutation	p.P304S	2
DHX9	BLCA	chr1	182827713	182827713	C	G	Missense_Mutation	p.Q280E	2
DHX9	PAAD	chr1	182844012	182844012	C	T	Nonsense_Mutation	p.Q580*	2
DHX9	STAD	chr1	182829162	182829162	A	C	Missense_Mutation	p.K392T	2
DHX9	UCEC	chr1	182828234	182828234	G	A	Silent	p.Q374	2
DHX9	STAD	chr1	182856560	182856560	C	T	Silent	p.G1268G	2
DHX9	UCEC	chr1	182856453	182856453	G	T	Missense_Mutation	p.D1233Y	2
DHX9	ESCA	chr1	182852698	182852698	C	-	Frame_Shift_Del		2
DHX9	HNSC	chr1	182812531	182812531	A	G	Missense_Mutation	p.I72V	2
DHX9	CESC	chr1	182845989	182845989	G	A	Missense_Mutation		2
DHX9	SKCM	chr1	182845222	182845222	C	T	Missense_Mutation	p.P618L	2
DHX9	ESCA	chr1	182850531	182850531	A	G	Silent	p.L919L	2
DHX9	LIHC	chr1	182848473	182848473	G	A	Missense_Mutation	p.G814S	2
DHX9	PAAD	chr1	182847247	182847247	C	T	Nonsense_Mutation	p.R764*	2
DHX9	STAD	chr1	182856359	182856359	C	T	Silent	p.G1201G	2
DHX9	UCEC	chr1	182835593	182835593	T	C	Silent	p.S449	2
DHX9	LIHC	chr1	182849641	182849641	C	T	Missense_Mutation		2
DHX9	CESC	chr1	182827939	182827939	A	C	Missense_Mutation		2
DHX9	LIHC	chr1	182836133	182836133	A	T	Silent	p.G504G	2
DHX9	UCEC	chr1	182835595	182835595	C	T	Missense_Mutation	p.A450V	2
DHX9	ESCA	chr1	182829305	182829305	A	T	Missense_Mutation		2
DHX9	LUAD	chr1	182847304	182847304	G	C	Missense_Mutation	p.E783Q	2
DHX9	SKCM	chr1	182852480	182852480	C	T	Missense_Mutation	p.P1041S	2
DHX9	PAAD	chr1	182846018	182846018	T	G	Silent		2
DHX9	LIHC	chr1	182823304	182823304	A	G	Missense_Mutation		2
DHX9	STAD	chr1	182827950	182827950	G	A	Missense_Mutation		2
DHX9	STAD	chr1	182856514	182856514	G	-	Frame_Shift_Del	p.R1253fs	2
DHX9	UCEC	chr1	182836147	182836147	T	G	Missense_Mutation	p.I509S	2
DHX9	STAD	chr1	182856514	182856515	-	G	Frame_Shift_Ins	p.R1253fs	1
DHX9	UCS	chr1	182829308	182829308	G	T	Missense_Mutation		1
DHX9	LIHC	chr1	182823255	182823255	C	G	Missense_Mutation	p.Q190E	1
DHX9	LUAD	chr1	182856400	182856400	G	T	Missense_Mutation	p.G1215V	1
DHX9	BLCA	chr1	182852729	182852729	G	C	Missense_Mutation		1
DHX9	LUAD	chr1	182845247	182845247	A	G	Silent	p.Q626Q	1
DHX9	UCEC	chr1	182850470	182850470	G	A	Missense_Mutation	p.R899Q	1
DHX9	COAD	chr1	182845280	182845280	C	T	Silent	p.I637I	1
DHX9	GBM	chr1	182811756	182811756	C	A	Missense_Mutation		1
DHX9	KIRP	chr1	182856445	182856445	C	G	Missense_Mutation		1
DHX9	LIHC	chr1	182836162	182836162	A	T	Missense_Mutation	p.H514L	1
DHX9	BLCA	chr1	182822501	182822501	G	A	Missense_Mutation		1
DHX9	HNSC	chr1	182856289	182856289	C	G	Missense_Mutation	p.S1178C	1
DHX9	LIHC	chr1	182850440	182850440	T	C	Missense_Mutation		1
DHX9	LIHC	chr1	182841478	182841478	T	-	Frame_Shift_Del	p.F522fs	1
DHX9	BLCA	chr1	182845243	182845243	C	G	Missense_Mutation		1
DHX9	BLCA	chr1	182849729	182849729	G	-	Frame_Shift_Del	p.M870fs	1
DHX9	READ	chr1	182828186	182828186	G	A	Silent	p.E358E	1
DHX9	STAD	chr1	182835644	182835644	A	-	Frame_Shift_Del	p.G466fs	1
DHX9	STAD	chr1	182853931	182853932	TA	-	Frame_Shift_Del	p.L1148fs	1
DHX9	ESCA	chr1	182828173	182828173	A	G	Splice_Site		1
DHX9	KIRC	chr1	182844045	182844045	A	-	Frame_Shift_Del	p.D590fs	1
DHX9	LIHC	chr1	182812563	182812563	T	-	Frame_Shift_Del	p.A82fs	1
DHX9	LUAD	chr1	182835642	182835642	G	C	Missense_Mutation	p.G466R	1
DHX9	CESC	chr1	182822496	182822496	C	A	Missense_Mutation		1
DHX9	LUAD	chr1	182836116	182836116	G	T	Nonsense_Mutation	p.E499*	1
DHX9	BLCA	chr1	182845653	182845653	C	T	Missense_Mutation		1
DHX9	BLCA	chr1	182847159	182847159	G	C	Missense_Mutation	p.Q734H	1
DHX9	UCEC	chr1	182841500	182841500	A	G	Missense_Mutation	p.D529G	1
DHX9	COAD	chr1	182850714	182850714	C	T	Missense_Mutation	p.T949I	1
DHX9	HNSC	chr1	182827949	182827949	G	A	Missense_Mutation		1
DHX9	KIRP	chr1	182850707	182850707	A	G	Missense_Mutation		1
DHX9	LIHC	chr1	182856333	182856333	G	T	Missense_Mutation	p.G1193C	1
DHX9	ESCA	chr1	182850531	182850531	A	G	Silent	p.L919	1
DHX9	LIHC	chr1	182845303	182845303	A	-	Frame_Shift_Del	p.E645fs	1
DHX9	BLCA	chr1	182835667	182835667	G	T	Missense_Mutation		1
DHX9	BLCA	chr1	182823164	182823164	G	A	Splice_Site	p.T160_splice	1
DHX9	READ	chr1	182829290	182829290	G	T	Missense_Mutation	p.A435S	1
DHX9	THYM	chr1	182827998	182827998	G	T	Missense_Mutation		1
DHX9	LIHC	chr1	182850422	182850422	T	C	Missense_Mutation	p.I883T	1
DHX9	LUAD	chr1	182829269	182829269	G	A	Missense_Mutation	p.D428N	1
DHX9	CESC	chr1	182812469	182812469	C	A	Missense_Mutation		1
DHX9	LUSC	chr1	182823280	182823280	A	G	Missense_Mutation	p.Y198C	1
DHX9	BLCA	chr1	182856269	182856269	C	T	Silent		1
DHX9	SKCM	chr1	182856370	182856370	C	T	Missense_Mutation	p.S1205F	1
DHX9	UCEC	chr1	182852697	182852698	-	C	Frame_Shift_Ins	p.T1063fs	1
DHX9	COAD	chr1	182852738	182852738	A	G	Silent	p.Q1076Q	1
DHX9	HNSC	chr1	182856289	182856289	C	G	Missense_Mutation		1
DHX9	KIRP	chr1	182856426	182856426	G	C	Missense_Mutation		1
DHX9	LIHC	chr1	182847265	182847265	C	G	Missense_Mutation	p.P770A	1
DHX9	ESCA	chr1	182852698	182852698	C	-	Frame_Shift_Del	p.L1065fs	1
DHX9	LIHC	chr1	182850728	182850728	T	C	Missense_Mutation		1
DHX9	LIHC	chr1	182852382	182852382	A	-	Frame_Shift_Del	p.E1008fs	1
DHX9	BLCA	chr1	182845355	182845355	G	T	Silent		1
DHX9	BLCA	chr1	182849629	182849630	-	A	Splice_Site	p.E838_splice	1
DHX9	SARC	chr1	182849633	182849633	G	T	Missense_Mutation		1
DHX9	THYM	chr1	182850658	182850658	G	T	Missense_Mutation	p.M930I	1
DHX9	CESC	chr1	182847248	182847248	G	G	Missense_Mutation		1
DHX9	LUSC	chr1	182847165	182847165	G	A	Silent	p.V736V	1
DHX9	BLCA	chr1	182823291	182823291	C	G	Missense_Mutation		1
DHX9	BLCA	chr1	182845243	182845243	C	G	Missense_Mutation	p.S625C	1
DHX9	PAAD	chr1	182844012	182844012	C	T	Nonsense_Mutation	p.Q580X	1
DHX9	SKCM	chr1	182845638	182845638	C	T	Missense_Mutation	p.R696C	1
DHX9	STAD	chr1	182828207	182828207	G	T	Missense_Mutation		1
DHX9	COAD	chr1	182853893	182853893	C	T	Missense_Mutation	p.R1136C	1
DHX9	HNSC	chr1	182812531	182812531	A	G	Missense_Mutation		1
DHX9	LGG	chr1	182856516	182856516	G	A	Missense_Mutation	p.G1254R	1
DHX9	LIHC	chr1	182852766	182852766	G	A	Missense_Mutation	p.D1086N	1
DHX9	HNSC	chr1	182852455	182852455	T	C	Silent	p.S1032S	1
DHX9	LIHC	chr1	182811741	182811741	A	-	Frame_Shift_Del	p.K14fs	1
DHX9	BLCA	chr1	182850414	182850414	C	G	Missense_Mutation		1
DHX9	SARC	chr1	182847290	182847290	G	T	Missense_Mutation		1
DHX9	STAD	chr1	182848383	182848383	A	C	Splice_Site	.	1
DHX9	THYM	chr1	182825701	182825701	C	T	Nonsense_Mutation	p.Q221X	1
DHX9	ESCA	chr1	182850475	182850475	G	T	Missense_Mutation	p.G901C	1
DHX9	BLCA	chr1	182856269	182856269	C	T	Silent	p.S1171S	1
DHX9	CESC	chr1	182812469	182812469	C	A	Missense_Mutation	p.S51Y	1
DHX9	LUSC	chr1	182846038	182846038	A	G	Missense_Mutation	p.K733_splice	1
DHX9	LIHC	chr1	182827769	182827770	-	C	Frame_Shift_Ins	p.FP298fs	1
DHX9	BLCA	chr1	182812529	182812529	G	A	Missense_Mutation		1
DHX9	BLCA	chr1	182850414	182850414	C	G	Missense_Mutation	p.I880M	1
DHX9	SKCM	chr1	182836128	182836128	C	T	Nonsense_Mutation	p.R503*	1
DHX9	COAD	chr1	182856344	182856344	C	T	Silent	p.S1196S	1
DHX9	HNSC	chr1	182850483	182850483	C	T	Silent		1
DHX9	LIHC	chr1	182811754	182811754	C	-	Frame_Shift_Del	p.T18fs	1
DHX9	BLCA	chr1	182850427	182850427	G	C	Missense_Mutation		1
DHX9	LUAD	chr1	182844009	182844009	A	G	Missense_Mutation	p.I579V	1
DHX9	SARC	chr1	182849649	182849649	G	T	Missense_Mutation		1
DHX9	MESO	chr1	182827770	182827770	C	T	Missense_Mutation		1
DHX9	SKCM	chr1	182836128	182836128	C	T	Nonsense_Mutation	p.R503X	1
DHX9	THYM	chr1	182856228	182856228	G	T	Missense_Mutation	p.G1158C	1
DHX9	ESCA	chr1	182845976	182845976	C	A	Silent	p.S712S	1
DHX9	LIHC	chr1	182811771	182811771	A	G	Missense_Mutation	p.R24G	1
DHX9	BLCA	chr1	182823291	182823291	C	G	Missense_Mutation	p.Q202E	1
DHX9	CESC	chr1	182844012	182844012	C	G	Missense_Mutation	p.Q580E	1
DHX9	LGG	chr1	182829136	182829136	G	A	Silent	p.Q383Q	1
DHX9	LIHC	chr1	182821466	182821466	G	-	Frame_Shift_Del	p.L117fs	1
DHX9	BLCA	chr1	182850427	182850427	G	C	Missense_Mutation	p.A885P	1
DHX9	SKCM	chr1	182823237	182823237	C	T	Missense_Mutation	p.R184C	1
DHX9	COAD	chr1	182856495	182856495	T	G	Missense_Mutation	p.F1247V	1
DHX9	HNSC	chr1	182856317	182856317	T	G	Silent		1
DHX9	ESCA	chr1	182829215	182829215	A	G	Missense_Mutation		1
DHX9	LIHC	chr1	182850527	182850527	T	-	Frame_Shift_Del	p.L919fs	1
DHX9	BLCA	chr1	182823204	182823204	C	T	Missense_Mutation		1
DHX9	LUAD	chr1	182845206	182845206	G	T	Missense_Mutation	p.G613C	1
DHX9	SARC	chr1	182852345	182852345	G	T	Missense_Mutation		1
DHX9	OV	chr1	182822552	182822566	CGGTAAGGCCAGCAC	-	Splice_Site	p.A159_splice	1
DHX9	UCEC	chr1	182811752	182811752	G	A	Missense_Mutation	p.M17I	1
DHX9	KIRC	chr1	182849684	182849684	G	T	Silent	p.L855L	1
DHX9	LIHC	chr1	182827944	182827944	A	G	Missense_Mutation	p.Q326R	1
DHX9	BLCA	chr1	182812529	182812529	G	A	Missense_Mutation	p.R71Q	1
DHX9	CESC	chr1	182845266	182845266	C	A	Missense_Mutation	p.P633T	1
DHX9	DLBC	chr1	182827297	182827297	G	A	Silent	p.L244L	1
DHX9	HNSC	chr1	182853912	182853912	C	T	Missense_Mutation		1
DHX9	LGG	chr1	182853875	182853875	C	T	Missense_Mutation	p.R1130C	1
DHX9	BLCA	chr1	182850557	182850557	C	G	Missense_Mutation		1
DHX9	BLCA	chr1	182823204	182823204	C	T	Missense_Mutation	p.H173Y	1
DHX9	PAAD	chr1	182847247	182847247	C	T	Nonsense_Mutation	p.R764X	1
DHX9	SKCM	chr1	182856252	182856252	C	G	Missense_Mutation	p.R1166G	1
DHX9	LIHC	chr1	182850695	182850695	A	-	Frame_Shift_Del	p.K943fs	1
DHX9	OV	chr1	181118923	181118923	A	G	Missense_Mutation	p.N981D	1
DHX9	UCEC	chr1	182835596	182835596	G	T	Silent	p.A450A	1
DHX9	COAD	chr1	182835628	182835630	GAG	-	In_Frame_Del	p.461_461del	1
DHX9	ESCA	chr1	182850527	182850527	T	C	Missense_Mutation	p.L918P	1
DHX9	LIHC	chr1	182828232	182828232	C	T	Nonsense_Mutation	p.Q374X	1
DHX9	CESC	chr1	182845989	182845989	G	A	Missense_Mutation	p.E717K	1
DHX9	DLBC	chr1	182850520	182850520	G	A	Missense_Mutation	p.V916I	1
DHX9	HNSC	chr1	182835672	182835672	G	A	Missense_Mutation		1
DHX9	LGG	chr1	182827295	182827295	C	A	Missense_Mutation	p.L244M	1
DHX9	BLCA	chr1	182850748	182850748	C	G	Silent		1
DHX9	BLCA	chr1	182853889	182853889	G	A	Missense_Mutation	p.M1134I	1
DHX9	SKCM	chr1	182821398	182821398	C	T	Missense_Mutation	p.P95S	1
DHX9	LIHC	chr1	182853771	182853771	A	G	Missense_Mutation		1
DHX9	LUAD	chr1	182822532	182822532	G	A	Silent	p.K152K	1
DHX9	BLCA	chr1	182853889	182853889	G	A	Missense_Mutation		1
DHX9	LUAD	chr1	182850427	182850427	G	T	Missense_Mutation	p.A885S	1
DHX9	SARC	chr1	182852711	182852711	G	T	Missense_Mutation		1
DHX9	OV	chr1	181079106	181079106	G	C	Missense_Mutation	p.D56H	1
DHX9	UCEC	chr1	182850487	182850487	C	T	Nonsense_Mutation	p.R905*	1
DHX9	COAD	chr1	182835667	182835667	G	A	Missense_Mutation	p.R474Q	1
DHX9	BLCA	chr1	182850557	182850557	C	G	Missense_Mutation	p.A928G	1
DHX9	ESCA	chr1	182828173	182828173	A	G	Splice_Site	e10-2	1
DHX9	HNSC	chr1	182845596	182845596	C	G	Missense_Mutation		1
DHX9	LGG	chr1	182827295	182827295	C	A	Missense_Mutation		1
DHX9	LIHC	chr1	182848503	182848503	C	-	Frame_Shift_Del	p.P825fs	1
DHX9	BLCA	chr1	182852703	182852703	C	T	Silent		1
DHX9	BLCA	chr1	182822539	182822539	C	G	Missense_Mutation	p.Q155E	1
DHX9	SKCM	chr1	182849694	182849694	C	T	Missense_Mutation	p.P859S	1
DHX9	STAD	chr1	182828207	182828207	G	T	Missense_Mutation	p.K365N	1
DHX9	UCS	chr1	182850453	182850453	C	T	Silent		1
DHX9	ESCA	chr1	182845976	182845976	C	A	Silent		1
DHX9	KICH	chr1	182827873	182827873	A	G	Silent	p.E302E	1
DHX9	BLCA	chr1	182822539	182822539	C	G	Missense_Mutation		1
DHX9	LUAD	chr1	182823294	182823294	G	T	Missense_Mutation	p.V203L	1
DHX9	SARC	chr1	182856417	182856417	G	T	Missense_Mutation	p.V1221F	1
DHX9	OV	chr1	182845604	182845604	A	G	Silent	p.L684	1
DHX9	COAD	chr1	182841515	182841515	A	G	Missense_Mutation	p.Y534C	1
DHX9	ESCA	chr1	182828173	182828173	A	G	Splice_Site	.	1
DHX9	KIRP	chr1	182822459	182822459	G	A	Missense_Mutation	p.G128E	1
DHX9	BLCA	chr1	182852703	182852703	C	T	Silent	p.L1065L	1
DHX9	HNSC	chr1	182856371	182856371	C	A	Silent		1
DHX9	LGG	chr1	182853875	182853875	C	T	Missense_Mutation		1
DHX9	LIHC	chr1	182850508	182850508	T	-	Frame_Shift_Del	p.F912fs	1
DHX9	BLCA	chr1	182849629	182849630	-	-	Splice_Site		1
DHX9	BLCA	chr1	182827872	182827872	A	G	Missense_Mutation	p.E302G	1
DHX9	PAAD	chr1	182847247	182847247	C	T	Nonsense_Mutation		1
DHX9	SKCM	chr1	182844081	182844083	GAT	-	In_Frame_Del	p.D605del	1
DHX9	STAD	chr1	182853931	182853932	TA	-	Frame_Shift_Del	p.1148_1148del	1
DHX9	STAD	chr1	182848383	182848383	A	C	Splice_Site	p.R784_splice	1
DHX9	UCS	chr1	182848417	182848417	G	A	Missense_Mutation		1
DHX9	KIRC	chr1	182849640	182849640	G	A	Missense_Mutation	p.A841T	1
DHX9	LIHC	chr1	182850418	182850418	A	G	Missense_Mutation		1
DHX9	BLCA	chr1	182827872	182827872	A	G	Missense_Mutation		1
DHX9	LUAD	chr1	182823168	182823168	C	T	Silent	p.L161L	1
DHX9	UCEC	chr1	182849676	182849676	C	T	Nonsense_Mutation	p.R853*	1
DHX9	COAD	chr1	182844020	182844020	C	T	Silent	p.T582T	1
DHX9	ESCA	chr1	182844088	182844088	A	T	Splice_Site	p.D605_splice	1
DHX9	KIRP	chr1	182828229	182828229	G	A	Missense_Mutation	p.E373K	1
DHX9	LIHC	chr1	182822524	182822524	T	C	Missense_Mutation	p.S150P	1
DHX9	BLCA	chr1	182823164	182823164	G	A	Splice_Site		1
DHX9	BLCA	chr1	182850748	182850748	C	G	Silent	p.L960L	1
DHX9	ESCA	chr1	182829305	182829305	A	T	Missense_Mutation	p.I440F	1
DHX9	HNSC	chr1	182852455	182852455	T	C	Silent		1
DHX9	LIHC	chr1	182852359	182852359	C	-	Frame_Shift_Del	p.Y1000fs	1
DHX9	BLCA	chr1	182845362	182845362	A	G	Missense_Mutation		1
DHX9	BLCA	chr1	182852729	182852729	G	C	Missense_Mutation	p.K1073N	1
DHX9	PRAD	chr1	182812496	182812496	A	G	Missense_Mutation	p.N60S	1

Copy number variation (CNV) of DHX9
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across DHX9
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
96562	BLCA	TCGA-C4-A0F7-01A	CNPY2	chr12	56708635	-	DHX9	chr1	182828175	+
91365	Non-Cancer	ERR315340	DHX9	chr1	182808591	+	ARF1	chr1	228284779	+
92900	N/A	BF957208	DHX9	chr1	182850402	-	FARS2	chr6	5750963	-
60933	PRAD	TCGA-HC-A631-01A	DHX9	chr1	182836178	+	FBXO7	chr22	32874968	+
96661	Non-Cancer	ERR315396	DHX9	chr1	182808591	+	GLUL	chr1	182357885	-
84193	Non-Cancer	ERR315396	DHX9	chr1	182808591	+	IVNS1ABP	chr1	185280454	-
99663	BRCA	TCGA-A2-A1FW-01A	DHX9	chr1	182809245	+	KDM5B	chr1	202745982	+
45603	N/A	AV681569	DHX9	chr1	182856884	+	MOB3B	chr9	27449669	+
87101	PRAD	TCGA-TK-A8OK	DHX9	chr1	182850782	+	PRELID1	chr5	176733422	+
87101	PRAD	TCGA-TK-A8OK-01A	DHX9	chr1	182850782	+	PRELID1	chr5	176733423	+
86349	N/A	BU733758	DHX9	chr1	182856547	-	PWP1	chr12	108102048	-
99042	PRAD	TCGA-G9-7522-01A	DHX9	chr1	182808591	+	RASAL2	chr1	178359235	+
73280	N/A	BE161368	DHX9	chr1	182853780	-	TMEM167A	chr5	82350337	-
98632	STAD	TCGA-HU-A4GQ	DHX9	chr1	182821479	+	VIM	chr10	17278292	+
84518	ESCA	TCGA-VR-A8EW	DHX9	chr1	182829319	+	XPR1	chr1	180651495	+
22736	SKCM	TCGA-EB-A42Z	DHX9	chr1	182829319	+	ZBTB37	chr1	173839334	+
22736	SKCM	TCGA-EB-A42Z-01A	DHX9	chr1	182829319	+	ZBTB37	chr1	173839335	+
22736	SKCM	TCGA-EB-A42Z-01A	DHX9	chr1	182829319	+	ZBTB37	chr1	173839338	+
96562	STAD	TCGA-BR-6706	RABGAP1L	chr1	174363283	+	DHX9	chr1	182835578	+
96562	OV	TCGA-13-0905	ROCK1	chr18	18690778	-	DHX9	chr1	182847155	+
96562	BRCA	TCGA-BH-A1ES	SLC4A1AP	chr2	27908144	+	DHX9	chr1	182827685	+
96575	BRCA	TCGA-BH-A0BW-01A	UCK2	chr1	165875206	+	DHX9	chr1	182850399	+

Top

Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

Top

Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRP	DHX9	0.00011400345372046	0.0031
TGCT	DHX9	0.0020524122418448	0.053
LUAD	DHX9	0.0113802659086555	0.28
READ	DHX9	0.0117915962056798	0.28
SKCM	DHX9	0.0170168233954872	0.39
ESCA	DHX9	0.0286781156228885	0.63
ACC	DHX9	0.0376203475752793	0.79
SARC	DHX9	5.42013386955855e-05	0.0015

Top

Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LIHC	DHX9	0.038889720778175	1
BRCA	DHX9	0.00714817967847303	0.23
ESCA	DHX9	0.00210929029301611	0.07

Top

Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source