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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: EIF4G1 (NCBI Gene ID:1981)

Gene Summary

Gene Summary

Gene Information	Gene Name: EIF4G1
	Gene ID: 1981
	Gene Symbol	EIF4G1
	Gene ID	1981
	Gene Name	eukaryotic translation initiation factor 4 gamma 1
	Synonyms	EIF-4G1\|EIF4F\|EIF4G\|EIF4GI\|P220\|PARK18
	Cytomap	3q27.1
	Type of Gene	protein-coding
	Description	eukaryotic translation initiation factor 4 gamma 1EIF4-gammaeIF-4-gamma 1eucaryotic translation initiation factor 4G
	Modification date	20200313
	UniProtAcc	Q04637

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0017148	Negative regulation of translation
GO:0006417	Regulation of translation
GO:0008135	Translation factor activity, RNA binding
GO:0045727	Positive regulation of translation
GO:0002181	Cytoplasmic translation
GO:0006413	Translational initiation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	EIF4G1	GO:1905612	positive regulation of mRNA cap binding	23409027
Hgene	EIF4G1	GO:1905618	positive regulation of miRNA mediated inhibition of translation	23409027

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
EIF4G1	(355.7 - 733]

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Translation Studies in PubMed

We searched PubMed using 'EIF4G1[title] AND translation [title] AND human.'

Gene	Title	PMID
EIF4G1	Eukaryotic Translation Initiation Factor 4 Gamma 1 (eIF4G1) is upregulated during Prostate cancer progression and modulates cell growth and metastasis	29748619

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000346169	184035108	184035285	In-frame

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000346169	184035108	184035285	5533	419	595	1599	49	108

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
KICH	EIF4G1	-1.46656081150743	0.00612920522689819

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
THYM	EIF4G1	3	2	0.0355750748202649	0.61760101010101	0.480200229568411	-0.821619552031148	-0.55998588199656

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
GBM	EIF4G1	-0.18412903	0.035190238
COAD	EIF4G1	-0.013982945	0.03815236

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with EIF4G1 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
ESCA	Cell metabolism gene	EIF4G1	PSMD2	0.843795657	2.47E-54
GBM	Cell metabolism gene	EIF4G1	AGPAT6	0.815163046	3.62E-42
GBM	Epifactor	EIF4G1	KDM2A	0.811092684	1.91E-41
GBM	IUPHAR	EIF4G1	KDM2A	0.811092684	1.91E-41
GBM	IUPHAR	EIF4G1	PCSK7	0.815485381	3.17E-42
GBM	TF	EIF4G1	KDM2A	0.811092684	1.91E-41
LUSC	Cell metabolism gene	EIF4G1	PSMD2	0.820908998	3.53E-136
TGCT	Cell metabolism gene	EIF4G1	GMPS	0.80698109	4.74E-37
TGCT	Cell metabolism gene	EIF4G1	PSMD2	0.857264781	2.99E-46
TGCT	CGC	EIF4G1	GMPS	0.80698109	4.74E-37
THYM	TF	EIF4G1	ATF6	0.811615072	8.65E-30
UCS	TF	EIF4G1	ATF6	0.811615072	8.65E-30
UVM	Cell metabolism gene	EIF4G1	PSMD2	0.846167229	5.06E-23
UVM	CGC	EIF4G1	NCKIPSD	0.826765438	3.52E-21
UVM	Epifactor	EIF4G1	BRPF1	0.805391203	2.13E-19
UVM	Epifactor	EIF4G1	RUVBL1	0.819735525	1.44E-20
UVM	IUPHAR	EIF4G1	GPR153	0.800179647	5.38E-19
UVM	IUPHAR	EIF4G1	BRPF1	0.805391203	2.13E-19
UVM	TSG	EIF4G1	PTPN23	0.866239412	3.23E-25

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
LUSC	EIF4G1	MKNK1	-1.7724058315911	0.000119179323433261
LUAD	EIF4G1	EIF4A2	1.8359785836448	0.000162905479402723
LUAD	EIF4G1	MKNK1	-1.64881335054025	0.000184346986492713
HNSC	EIF4G1	EIF1	-4.13399438210909	0.000228392819053625
ESCA	EIF4G1	HNRNPD	-3.95797649272358	0.0009765625
CHOL	EIF4G1	PABPC1	-4.56272528815353	0.00390625
COAD	EIF4G1	HNRNPD	-6.12601039633597	0.00427913665771485
LIHC	EIF4G1	EIF3E	-5.1722332599854	0.00593802028362182
KIRP	EIF4G1	MKNK1	-1.83550648151309	0.00608485564589501
PRAD	EIF4G1	EIF1	1.32822648991353	0.00674237731133815
KICH	EIF4G1	HNRNPD	-1.0797746293114	0.00737094879150391
BLCA	EIF4G1	PABPC1	1.31485302792746	0.0180816650390625
ESCA	EIF4G1	EIF4A1	-1.24538073199285	0.0419921875
LUAD	EIF4G1	EIF3B	-5.80435587546762	1.0542655358657e-09
LUAD	EIF4G1	HNRNPD	-3.62564314494355	1.52449212829498e-06
KIRC	EIF4G1	EIF3B	-1.56313263784517	2.35252849767166e-12
BRCA	EIF4G1	EIF4B	-2.16032742029696	2.35556737304054e-22
LIHC	EIF4G1	PABPC1	-1.72076961362188	2.98009622125841e-06
STAD	EIF4G1	EIF3B	-4.7724660972007	3.25962901115418e-08
HNSC	EIF4G1	EIF3B	2.6202554263604	4.48234413852334e-06
KIRC	EIF4G1	MKNK1	-1.36155431828684	4.53899662243056e-11
KIRP	EIF4G1	EIF3B	-2.7592297042974	4.6566128730774e-09
KICH	EIF4G1	EIF4E	1.61675210562671	6.55651092529297e-06
KIRC	EIF4G1	EIF4B	1.14997140510474	7.59366366705366e-09
KIRC	EIF4G1	EIF3E	-4.49824101219462	7.8509870430991e-09
KICH	EIF4G1	EIF4A1	1.14485583309571	8.16583633422851e-06
PRAD	EIF4G1	PABPC1	-2.10200318363476	8.55379952759014e-07
BRCA	EIF4G1	EIF3E	-1.48408348062463	9.51829316317813e-08

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with EIF4G1

EIF4A2, NELFCD, EIF4A1, GABARAPL2, MAGEA6, MKNK2, PDCD4, EIF4E, EIF3B, Eif4e, EIF3A, EIF3I, MKNK1, NCBP1, PABPC1, HNRNPD, USP10, EIF3H, EIF3F, USP3, G3BP1, Eif3a, UBE3A, CENPU, RAD21, SIRT7, ISG15, CUL3, TRAF2, EIF4G2, EIF4B, EIF4G3, SF3A3, FTL, RAB31, ESR1, FN1, VCAM1, HTRA2, ZFYVE9, ITGA4, BRCA1, GK, TARDBP, AIMP1, AIMP2, EEF1E1, IQGAP1, PSMB8, PTBP1, QARS, LGR4, POLDIP3, CUL7, CCDC8, MAMDC2, PSMC3, UNK, DCTN4, KIAA0020, NAT10, PUS7, SF3A1, SF3A2, SKIV2L2, FBL, NUP50, PABPC4, POLE, SF3B3, TNKS1BP1, NTRK1, gag, HERC2, SRPK2, CLCN2, HSPA5, TOR1AIP1, SGTB, MRPL9, ACTR5, CNTROB, Gspt1, Eif3e, Pabpc1, Taok2, FOXB1, FOXL1, MCM2, RC3H1, SLBP, CDH1, GCHFR, NFATC2IP, EMILIN1, CYLD, DLD, DLST, PDHA1, TRIM25, ATP5A1, EXOSC2, MED28, MFAP1, MRPL22, MRPL32, PTTG1, RPL35, TAF2, XRN2, ZNF598, FBXO7, CHAF1B, TRIM14, TMPO, OTUD6B, HSPA8, UBE2M, EFTUD2, AAR2, RPTOR, TNIP2, CHD3, CHD4, RNF4, SPDL1, BPLF1, ESR2, AGR2, RECQL4, FBXW7, MYC, CDK9, CDC37, GRWD1, KIAA1429, SRSF3, RC3H2, PHB, ZC3H7A, EIF1, NR2C2, UBQLN2, GBF1, ATXN3, APEX1, DYRK1A, CD74, DDX60, GCH1, SNRNP70, GSK3B, BIRC3, STAU1, LMBR1L, G3BP2, NFX1, WWP2, BRD7, MATR3, PSEN1, CMTR1, SMARCD1, DTX2, KRT31, ENKD1, FXR2, CDKN2D, KRT34, A1CF, WDYHV1, PEF1, ATPAF2, CTBP2, CCDC57, CIB1, PLEKHA4, HIF1AN, NHLRC2, ITPR2, YLPM1, LRRC31, CIT, KIF14, KIF23, FASN, SUMO2, NDN, Rnf183, BRD4, NUPR1, Apc2, RBM39, FBP1, FMR1, EIF4EBP1, EIF4EBP2, EIF4ENIF1, EIF3D, EIF3C, EIF3K, EIF3L, EIF3G, EIF3M, EIF3E, ANGEL1, DDX58, UFL1, LINC00152, FZR1, WDR5, EDEM1, IFT22, BTF3, EIF3J, FGD5, HECTD1, SLFN11, CUL4B, KLF16, KLF8, MAGEL2,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
EIF4G1	chr3	184033346	T	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184033408	A	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184034340	GT	G	Deletion	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184035129	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant,SO:0001623\|5_prime_UTR_variant,SO:0001627\|intron_variant	SO:0001819\|synonymous_variant,SO:0001623\|5_prime_UTR_variant,SO:0001627\|intron_variant
EIF4G1	chr3	184035392	T	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184035448	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184037214	GGT	G	Microsatellite	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184037235	GTGTGTGTGTGTGTGTGTGTT	G	Deletion	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184037237	GTGTGTGTGTGTGTGTGTT	G	Microsatellite	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184037239	GTGTGTGTGTGTGTGTT	G	Deletion	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184037533	A	G	single_nucleotide_variant	Benign	not_specified	SO:0001583\|missense_variant,SO:0002073\|no_sequence_alteration,SO:0001623\|5_prime_UTR_variant	SO:0001583\|missense_variant,SO:0002073\|no_sequence_alteration,SO:0001623\|5_prime_UTR_variant
EIF4G1	chr3	184037716	T	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184038874	A	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184038969	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184039221	C	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184039304	A	G	single_nucleotide_variant	Benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184039666	A	G	single_nucleotide_variant	Benign	Parkinson_disease_18\|not_specified\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184039766	AAGGAGAAGC	A	Microsatellite	Benign	not_specified	SO:0001822\|inframe_deletion	SO:0001822\|inframe_deletion
EIF4G1	chr3	184039843	A	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184039877	C	T	single_nucleotide_variant	risk_factor	Parkinson_disease_18	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184039937	C	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184040371	G	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184040396	C	T	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184040606	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184041256	G	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184041499	C	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184041971	A	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184042125	A	C	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184043282	A	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184043285	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184043636	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184044433	C	T	single_nucleotide_variant	Benign	Parkinson_disease_18\|not_specified\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184045189	G	A	single_nucleotide_variant	risk_factor	Parkinson_disease_18	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184045397	C	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184045410	T	C	single_nucleotide_variant	Benign	not_specified\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184045661	T	A	single_nucleotide_variant	Uncertain_significance	Parkinson_disease_18	SO:0001583\|missense_variant	SO:0001583\|missense_variant
EIF4G1	chr3	184045710	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184045799	A	G	single_nucleotide_variant	Benign	Parkinson_disease_18\|not_specified\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184046042	A	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184046102	C	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184046355	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184046470	C	T	single_nucleotide_variant	Benign	not_specified\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184049143	C	T	single_nucleotide_variant	Benign	not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184049382	C	T	single_nucleotide_variant	Benign	not_specified\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184049385	C	T	single_nucleotide_variant	Benign/Likely_benign	not_specified\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184049399	G	A	single_nucleotide_variant	Benign	not_specified\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
EIF4G1	chr3	184049756	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184049766	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184049774	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184049807	C	T	single_nucleotide_variant	Benign	not_specified\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
EIF4G1	chr3	184052334	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
EIF4G1	BLCA	chr3	184039744	184039746	GAA	-	In_Frame_Del	p.E465del	10
EIF4G1	CESC	chr3	184046470	184046470	C	T	Silent		5
EIF4G1	LUAD	chr3	184039092	184039092	C	T	Silent	p.I240I	5
EIF4G1	LUAD	chr3	184044714	184044714	C	G	Nonsense_Mutation	p.S1125*	4
EIF4G1	LIHC	chr3	184043650	184043650	C	-	Frame_Shift_Del	p.P1046fs	4
EIF4G1	LUAD	chr3	184039405	184039405	C	T	Missense_Mutation	p.L345F	4
EIF4G1	UCEC	chr3	184038427	184038427	C	T	Nonsense_Mutation	p.R183*	4
EIF4G1	SKCM	chr3	184039162	184039162	C	T	Missense_Mutation	p.P264S	3
EIF4G1	LIHC	chr3	184049265	184049265	G	A	Silent		3
EIF4G1	LIHC	chr3	184039824	184039824	C	-	Frame_Shift_Del	p.L484fs	3
EIF4G1	BRCA	chr3	184035137	184035137	C	T	Missense_Mutation	p.P59L	3
EIF4G1	HNSC	chr3	184046477	184046477	C	T	Missense_Mutation		3
EIF4G1	LGG	chr3	184043126	184043126	C	T	Missense_Mutation	p.R977C	3
EIF4G1	COAD	chr3	184038752	184038752	C	T	Missense_Mutation	p.T223M	3
EIF4G1	CESC	chr3	184052538	184052538	G	T	Missense_Mutation		3
EIF4G1	LIHC	chr3	184043088	184043088	A	-	Frame_Shift_Del	p.E964fs	3
EIF4G1	UCEC	chr3	184041616	184041616	A	G	Missense_Mutation	p.M775V	3
EIF4G1	SKCM	chr3	184041252	184041252	C	T	Silent	p.I716I	3
EIF4G1	HNSC	chr3	184039336	184039336	G	A	Missense_Mutation	p.E322K	3
EIF4G1	HNSC	chr3	184033995	184033995	C	T	Nonsense_Mutation	p.Q46*	2
EIF4G1	UCEC	chr3	184045227	184045227	C	T	Missense_Mutation	p.R1218W	2
EIF4G1	SKCM	chr3	184049375	184049375	G	A	Missense_Mutation	p.R1460Q	2
EIF4G1	KIRC	chr3	184039116	184039116	T	C	Silent	p.P248P	2
EIF4G1	UCEC	chr3	184039155	184039155	G	A	Silent	p.S261	2
EIF4G1	PAAD	chr3	184040619	184040619	G	T	Missense_Mutation		2
EIF4G1	UCEC	chr3	184049787	184049787	C	T	Silent	p.L1511	2
EIF4G1	SKCM	chr3	184035215	184035215	C	T	Missense_Mutation	p.S85F	2
EIF4G1	LGG	chr3	184042736	184042736	G	A	Missense_Mutation	p.G898E	2
EIF4G1	BLCA	chr3	184041700	184041700	G	C	Missense_Mutation	p.E804Q	2
EIF4G1	SKCM	chr3	184040702	184040702	C	T	Missense_Mutation	p.P630L	2
EIF4G1	LIHC	chr3	184043644	184043644	G	-	Frame_Shift_Del	p.G1044fs	2
EIF4G1	UCEC	chr3	184039456	184039456	A	G	Missense_Mutation	p.N362D	2
EIF4G1	PAAD	chr3	184042077	184042077	A	G	Missense_Mutation		2
EIF4G1	UCEC	chr3	184052638	184052638	C	T	Missense_Mutation	p.S1581F	2
EIF4G1	HNSC	chr3	184039824	184039824	C	T	Silent	p.L484L	2
EIF4G1	SKCM	chr3	184052517	184052517	C	T	Silent	p.L1542L	2
EIF4G1	BLCA	chr3	184040229	184040229	C	T	Silent	p.A533A	2
EIF4G1	BLCA	chr3	184041700	184041700	G	C	Missense_Mutation		2
EIF4G1	LIHC	chr3	184040633	184040633	A	G	Missense_Mutation		2
EIF4G1	SKCM	chr3	184035254	184035254	C	T	Missense_Mutation	p.A98V	2
EIF4G1	UCEC	chr3	184039537	184039537	G	A	Missense_Mutation	p.E389K	2
EIF4G1	PAAD	chr3	184045152	184045152	C	T	Missense_Mutation		2
EIF4G1	ESCA	chr3	184040687	184040687	C	T	Missense_Mutation	p.A632V	2
EIF4G1	HNSC	chr3	184039888	184039888	C	G	Missense_Mutation	p.Q506E	2
EIF4G1	SKCM	chr3	184042702	184042702	G	A	Missense_Mutation	p.E887K	2
EIF4G1	CHOL	chr3	184039802	184039802	A	T	Missense_Mutation		2
EIF4G1	SKCM	chr3	184035255	184035255	C	T	Silent	p.A98A	2
EIF4G1	BLCA	chr3	184040744	184040744	T	G	Splice_Site		2
EIF4G1	UCEC	chr3	184039863	184039863	G	T	Missense_Mutation	p.Q497H	2
EIF4G1	PAAD	chr3	184052556	184052556	G	A	Missense_Mutation		2
EIF4G1	UCS	chr3	184046479	184046480	-	TACCTAGCGGA	Frame_Shift_Ins	p.P1340fs	2
EIF4G1	ESCA	chr3	184042019	184042019	G	T	Missense_Mutation	p.V842L	2
EIF4G1	SKCM	chr3	184043652	184043652	C	T	Silent	p.P1046P	2
EIF4G1	LUAD	chr3	184039251	184039251	A	G	Missense_Mutation	p.I293M	2
EIF4G1	CHOL	chr3	184040641	184040641	A	C	Missense_Mutation		2
EIF4G1	SKCM	chr3	184035236	184035236	C	T	Missense_Mutation	p.S92F	2
EIF4G1	KIRP	chr3	184041746	184041746	T	C	Missense_Mutation	p.M825T	2
EIF4G1	CESC	chr3	184040704	184040704	G	A	Missense_Mutation		2
EIF4G1	UCEC	chr3	184041200	184041200	G	A	Missense_Mutation	p.G698D	2
EIF4G1	SKCM	chr3	184039114	184039114	C	T	Missense_Mutation	p.P248S	2
EIF4G1	LGG	chr3	184043126	184043126	C	T	Missense_Mutation		2
EIF4G1	LIHC	chr3	184049265	184049265	G	A	Silent	p.V1423V	2
EIF4G1	LUAD	chr3	184039223	184039223	C	G	Missense_Mutation	p.S284C	2
EIF4G1	TGCT	chr3	184045410	184045410	T	C	Missense_Mutation		2
EIF4G1	SARC	chr3	184044418	184044418	G	A	Splice_Site		2
EIF4G1	CESC	chr3	184040742	184040742	G	C	Missense_Mutation		2
EIF4G1	UCEC	chr3	184041244	184041244	C	T	Missense_Mutation	p.R713C	2
EIF4G1	ESCA	chr3	184044684	184044684	G	T	Missense_Mutation	p.R1121L	2
EIF4G1	LGG	chr3	184042736	184042736	G	A	Missense_Mutation		2
EIF4G1	SARC	chr3	184039474	184039474	G	A	Missense_Mutation		2
EIF4G1	KICH	chr3	184038753	184038753	G	A	Silent	p.T223T	2
EIF4G1	STAD	chr3	184039582	184039582	C	T	Missense_Mutation		2
EIF4G1	CESC	chr3	184043121	184043121	G	A	Missense_Mutation		2
EIF4G1	UCEC	chr3	184042682	184042682	G	A	Missense_Mutation	p.R879H	2
EIF4G1	SKCM	chr3	184049296	184049296	C	T	Missense_Mutation	p.P1434S	2
EIF4G1	SKCM	chr3	184045168	184045168	C	T	Missense_Mutation	p.P1199L	2
EIF4G1	STAD	chr3	184040725	184040725	G	A	Missense_Mutation		2
EIF4G1	LIHC	chr3	184040193	184040193	A	-	Frame_Shift_Del	p.L521fs	2
EIF4G1	UCEC	chr3	184043161	184043161	G	A	Silent	p.G39E	2
EIF4G1	SKCM	chr3	184049273	184049273	C	T	Missense_Mutation	p.T1426I	2
EIF4G1	CESC	chr3	184045425	184045425	C	G	Missense_Mutation		2
EIF4G1	UCEC	chr3	184044716	184044716	G	T	Missense_Mutation	p.A1125S	2
EIF4G1	ESCA	chr3	184049760	184049760	G	T	Missense_Mutation	p.A1509S	2
EIF4G1	LIHC	chr3	184045645	184045645	G	A	Missense_Mutation		2
EIF4G1	LUAD	chr3	184040362	184040362	C	T	Nonsense_Mutation	p.Q547*	2
EIF4G1	UCEC	chr3	184038426	184038426	T	C	Silent	p.I182	2
EIF4G1	HNSC	chr3	184046477	184046477	C	T	Missense_Mutation	p.L1339F	2
EIF4G1	COAD	chr3	184052538	184052538	G	A	Missense_Mutation	p.A1549T	2
EIF4G1	HNSC	chr3	184039612	184039612	G	A	Missense_Mutation	p.D414N	2
EIF4G1	UCEC	chr3	184045148	184045148	G	T	Missense_Mutation	p.E1191D	2
EIF4G1	PAAD	chr3	184040619	184040619	G	T	Missense_Mutation	p.K602N	2
EIF4G1	ACC	chr3	184049834	184049834	C	T	Silent	p.Y1527Y	2
EIF4G1	LIHC	chr3	184039550	184039550	C	G	Missense_Mutation		2
EIF4G1	LIHC	chr3	184035257	184035257	C	-	Frame_Shift_Del	p.S99fs	2
EIF4G1	BLCA	chr3	184039489	184039489	G	C	Missense_Mutation		2
EIF4G1	BRCA	chr3	184039523	184039523	C	A	Missense_Mutation	p.P384Q	2
EIF4G1	HNSC	chr3	184039136	184039136	C	T	Missense_Mutation	p.S255L	2
EIF4G1	DLBC	chr3	184039304	184039304	A	G	Missense_Mutation	p.Y318C	1
EIF4G1	HNSC	chr3	184040413	184040413	C	T	Missense_Mutation		1
EIF4G1	KIRP	chr3	184038756	184038756	C	A	Silent		1
EIF4G1	STAD	chr3	184040725	184040725	G	A	Missense_Mutation	p.D645N	1
EIF4G1	STAD	chr3	184042123	184042123	T	C	Silent	p.D876D	1
EIF4G1	LIHC	chr3	184044734	184044734	C	-	Frame_Shift_Del	p.P1132fs	1
EIF4G1	STAD	chr3	184043072	184043072	T	C	Missense_Mutation	p.Y958H	1
EIF4G1	LUAD	chr3	184040239	184040239	G	C	Splice_Site		1
EIF4G1	BLCA	chr3	184044703	184044703	G	A	Silent		1
EIF4G1	CESC	chr3	184040742	184040742	G	C	Splice_Site	p.K643_splice	1
EIF4G1	LUAD	chr3	184049748	184049748	C	T	Nonsense_Mutation	p.R1498*	1
EIF4G1	PAAD	chr3	184052556	184052556	G	A	Missense_Mutation	p.V1555M	1
EIF4G1	STAD	chr3	184049322	184049322	G	T	Missense_Mutation	p.E1441D	1
EIF4G1	ACC	chr3	184042024	184042025	TG	-	Frame_Shift_Del	p.837_837del	1
EIF4G1	BLCA	chr3	184049370	184049370	C	G	Missense_Mutation	p.N1458K	1
EIF4G1	LUSC	chr3	184042076	184042076	G	C	Missense_Mutation	p.D854H	1
EIF4G1	PAAD	chr3	184038482	184038482	G	A	Missense_Mutation	p.R201H	1
EIF4G1	ESCA	chr3	184040221	184040221	C	A	Missense_Mutation		1
EIF4G1	HNSC	chr3	184044414	184044414	G	A	Missense_Mutation		1
EIF4G1	HNSC	chr3	184046477	184046477	C	T	Missense_Mutation	p.L1338F	1
EIF4G1	SKCM	chr3	184042684	184042684	C	T	Silent	p.L881L	1
EIF4G1	LIHC	chr3	184039550	184039550	C	G	Missense_Mutation	p.P400R	1
EIF4G1	STAD	chr3	184044360	184044360	C	T	Nonsense_Mutation	p.R1097X	1
EIF4G1	LUAD	chr3	184046479	184046479	C	T	Silent	p.L1339L	1
EIF4G1	SKCM	chr3	184035276	184035276	C	T	Silent	p.I105I	1
EIF4G1	STAD	chr3	184040475	184040475	T	C	Silent	p.A584A	1
EIF4G1	LUAD	chr3	184049544	184049544	C	G	Missense_Mutation	p.S1476C	1
EIF4G1	THYM	chr3	184042723	184042723	C	T	Missense_Mutation	p.R900W	1
EIF4G1	BLCA	chr3	184040478	184040478	G	C	Missense_Mutation		1
EIF4G1	COAD	chr3	184037588	184037588	C	T	Missense_Mutation	p.T179M	1
EIF4G1	GBM	chr3	184044341	184044341	G	A	Silent	p.Q1083Q	1
EIF4G1	HNSC	chr3	184041346	184041346	C	T	Nonsense_Mutation	p.R748*	1
EIF4G1	LUSC	chr3	184045465	184045465	G	T	Missense_Mutation	p.E1251D	1
EIF4G1	PAAD	chr3	184045152	184045152	C	T	Missense_Mutation	p.R1194W	1
EIF4G1	DLBC	chr3	184049807	184049807	C	T	Silent	p.D1524D	1
EIF4G1	HNSC	chr3	184046444	184046444	G	A	Missense_Mutation	p.E1328K	1
EIF4G1	STAD	chr3	184039582	184039582	C	T	Missense_Mutation	p.L411F	1
EIF4G1	STAD	chr3	184043127	184043127	G	A	Missense_Mutation	p.R983H	1
EIF4G1	LIHC	chr3	184039274	184039274	C	-	Frame_Shift_Del	p.T301fs	1
EIF4G1	STAD	chr3	184041688	184041688	G	T	Missense_Mutation	p.D799Y	1
EIF4G1	LUAD	chr3	184045208	184045208	G	T	Silent	p.T1211T	1
EIF4G1	CESC	chr3	184040704	184040704	G	A	Missense_Mutation	p.E631K	1
EIF4G1	LIHC	chr3	184049265	184049265	G	A	Silent	p.V1429V	1
EIF4G1	STAD	chr3	184042726	184042726	C	T	Missense_Mutation	p.R901C	1
EIF4G1	LUAD	chr3	184052538	184052538	G	T	Missense_Mutation	p.A1549S	1
EIF4G1	STAD	chr3	184040890	184040890	G	A	Missense_Mutation	p.R650Q	1
EIF4G1	ACC	chr3	184042024	184042025	TG	-	Frame_Shift_Del	p.TV837fs	1
EIF4G1	BLCA	chr3	184035528	184035528	G	T	Silent	p.P116P	1
EIF4G1	LUSC	chr3	184045480	184045480	C	A	Silent	p.L1256L	1
EIF4G1	PRAD	chr3	184045675	184045675	C	T	Missense_Mutation	p.R1281W	1
EIF4G1	ESCA	chr3	184040687	184040687	C	T	Missense_Mutation		1
EIF4G1	READ	chr3	184044407	184044407	C	A	Silent	p.P1106P	1
EIF4G1	HNSC	chr3	184044351	184044351	C	T	Missense_Mutation	p.P1087S	1
EIF4G1	SKCM	chr3	184044729	184044729	C	T	Missense_Mutation	p.A1130V	1
EIF4G1	LIHC	chr3	184037534	184037534	C	G	Missense_Mutation		1
EIF4G1	HNSC	chr3	184049828	184049828	G	T	Silent	p.A1525A	1
EIF4G1	KIRC	chr3	184049133	184049133	G	C	Missense_Mutation	p.G1415A	1
EIF4G1	SKCM	chr3	184049088	184049088	C	T	Missense_Mutation	p.A1400V	1
EIF4G1	STAD	chr3	184046703	184046703	T	A	Silent	p.I1362I	1
EIF4G1	THYM	chr3	184039153	184039153	T	C	Missense_Mutation	p.S268P	1
EIF4G1	BLCA	chr3	184049082	184049082	G	T	Missense_Mutation		1
EIF4G1	COAD	chr3	184038481	184038481	C	T	Missense_Mutation	p.R201C	1
EIF4G1	GBM	chr3	184044341	184044341	G	A	Silent		1
EIF4G1	LUSC	chr3	184039232	184039232	G	A	Missense_Mutation	p.G287E	1
EIF4G1	PAAD	chr3	184042077	184042077	A	G	Missense_Mutation	p.D855G	1
EIF4G1	DLBC	chr3	184037523	184037523	C	T	Silent	p.G164G	1
EIF4G1	HNSC	chr3	184039824	184039824	C	T	Silent		1
EIF4G1	STAD	chr3	184045790	184045790	G	A	Missense_Mutation	p.G1325E	1
EIF4G1	STAD	chr3	184041688	184041688	G	T	Missense_Mutation	p.D806Y	1
EIF4G1	LIHC	chr3	184039541	184039541	C	-	Frame_Shift_Del	p.S390fs	1
EIF4G1	STAD	chr3	184046450	184046450	A	G	Missense_Mutation	p.M1329V	1
EIF4G1	CESC	chr3	184038632	184038632	C	T	Missense_Mutation	p.A47V	1
EIF4G1	LIHC	chr3	184039489	184039489	G	T	Nonsense_Mutation	p.E373*	1
EIF4G1	STAD	chr3	184049322	184049322	G	T	Missense_Mutation	p.E1448D	1
EIF4G1	LUAD	chr3	184039242	184039242	G	C	Missense_Mutation	p.M290I	1
EIF4G1	STAD	chr3	184042855	184042855	C	T	Missense_Mutation	p.R937C	1
EIF4G1	BLCA	chr3	184039844	184039844	T	C	Missense_Mutation	p.I491T	1
EIF4G1	LUSC	chr3	184038451	184038451	G	T	Missense_Mutation	p.D191Y	1
EIF4G1	PRAD	chr3	184046495	184046496	-	T	Frame_Shift_Ins	p.N1345fs	1
EIF4G1	ESCA	chr3	184042019	184042019	G	T	Missense_Mutation		1
EIF4G1	SARC	chr3	184049143	184049143	C	T	Silent		1
EIF4G1	HNSC	chr3	184043328	184043328	G	T	Nonsense_Mutation	p.E1008*	1
EIF4G1	SKCM	chr3	184043641	184043641	C	T	Missense_Mutation	p.R1043C	1
EIF4G1	GBM	chr3	184052651	184052651	C	G	Missense_Mutation		1
EIF4G1	HNSC	chr3	184043060	184043060	C	T	Nonsense_Mutation	p.R955*	1
EIF4G1	KIRC	chr3	184049812	184049812	A	G	Missense_Mutation	p.Q1520R	1
EIF4G1	SKCM	chr3	184049089	184049089	C	T	Silent	p.A1400A	1
EIF4G1	STAD	chr3	184049520	184049520	A	T	Missense_Mutation	p.N1467I	1
EIF4G1	THYM	chr3	184038488	184038488	C	T	Missense_Mutation	p.A210V	1
EIF4G1	BLCA	chr3	184042052	184042052	C	A	Silent		1
EIF4G1	CESC	chr3	184049281	184049281	G	A	Missense_Mutation		1
EIF4G1	LUAD	chr3	184046479	184046479	C	T	Silent	p.L1338L	1
EIF4G1	LUSC	chr3	184039394	184039394	C	A	Missense_Mutation	p.S341Y	1
EIF4G1	UCS	chr3	184046479	184046480	-	-	Frame_Shift_Ins		1
EIF4G1	PAAD	chr3	184046477	184046477	C	A	Missense_Mutation	p.L1339I	1
EIF4G1	HNSC	chr3	184039888	184039888	C	G	Missense_Mutation		1
EIF4G1	LGG	chr3	184046467	184046467	C	T	Silent	p.P1335P	1
EIF4G1	STAD	chr3	184043072	184043072	T	C	Missense_Mutation	p.Y965H	1
EIF4G1	STAD	chr3	184045412	184045412	A	-	Frame_Shift_Del	p.L1240fs	1
EIF4G1	LIHC	chr3	184042049	184042049	A	-	Frame_Shift_Del	p.N846fs	1
EIF4G1	STAD	chr3	184035509	184035509	G	A	Missense_Mutation	p.R110H	1
EIF4G1	BLCA	chr3	184043095	184043095	C	A	Silent	p.I966I	1
EIF4G1	CESC	chr3	184040704	184040704	G	A	Missense_Mutation	p.E638K	1
EIF4G1	LIHC	chr3	184045645	184045645	G	A	Missense_Mutation	p.A1271T	1
EIF4G1	STAD	chr3	184042855	184042855	C	T	Missense_Mutation	p.R944C	1
EIF4G1	LUAD	chr3	184042135	184042135	G	A	Splice_Site	p.T874_splice	1
EIF4G1	STAD	chr3	184039599	184039599	G	A	Silent	p.S409S	1
EIF4G1	BLCA	chr3	184044683	184044683	C	A	Missense_Mutation		1
EIF4G1	BLCA	chr3	184039813	184039813	G	C	Missense_Mutation	p.E481Q	1
EIF4G1	MESO	chr3	184044334	184044334	A	G	Missense_Mutation		1
EIF4G1	PRAD	chr3	184039469	184039469	C	A	Missense_Mutation	p.P366Q	1
EIF4G1	ESCA	chr3	184046732	184046732	C	T	Missense_Mutation	p.A1379V	1
EIF4G1	SARC	chr3	184043669	184043669	G	T	Missense_Mutation		1
EIF4G1	HNSC	chr3	184045463	184045463	G	C	Missense_Mutation	p.E1251Q	1
EIF4G1	SKCM	chr3	184040494	184040494	G	A	Missense_Mutation	p.E591K	1
EIF4G1	COAD	chr3	184039758	184039758	A	G	Silent	p.E462E	1
EIF4G1	HNSC	chr3	184043113	184043113	G	A	Silent		1
EIF4G1	HNSC	chr3	184043328	184043328	G	T	Nonsense_Mutation	p.E1009*	1
EIF4G1	KIRP	chr3	184042785	184042785	G	A	Silent	p.E920E	1
EIF4G1	SKCM	chr3	184033942	184033942	C	T	Missense_Mutation	p.T28I	1
EIF4G1	LIHC	chr3	184035133	184035133	C	-	Frame_Shift_Del	p.P59fs	1
EIF4G1	STAD	chr3	184043127	184043127	G	A	Missense_Mutation	p.R976H	1
EIF4G1	LUAD	chr3	184049592	184049592	T	A	Missense_Mutation	p.I1492N	1
EIF4G1	THYM	chr3	184042672	184042672	G	T	Nonsense_Mutation	p.E883X	1
EIF4G1	LUAD	chr3	184052538	184052538	G	T	Missense_Mutation	p.A1548S	1
EIF4G1	LUSC	chr3	184039421	184039421	C	T	Missense_Mutation	p.P350L	1
EIF4G1	PAAD	chr3	184039075	184039075	C	T	Missense_Mutation	p.R235W	1
EIF4G1	HNSC	chr3	184044351	184044351	C	T	Missense_Mutation		1
EIF4G1	HNSC	chr3	184044351	184044351	C	T	Missense_Mutation	p.P1088S	1
EIF4G1	LGG	chr3	184040467	184040467	C	T	Missense_Mutation	p.H582Y	1
EIF4G1	STAD	chr3	184040373	184040373	A	G	Silent	p.A557A	1
EIF4G1	LIHC	chr3	184049840	184049840	C	A	Silent	p.L1535L	1
EIF4G1	STAD	chr3	184049755	184049755	A	G	Missense_Mutation	p.D1507G	1
EIF4G1	STAD	chr3	184042123	184042123	T	C	Silent	p.D869D	1
EIF4G1	BLCA	chr3	184037587	184037587	A	G	Missense_Mutation	p.T179A	1
EIF4G1	CESC	chr3	184040742	184040742	G	C	Missense_Mutation	p.K650N	1
EIF4G1	LIHC	chr3	184039550	184039550	C	G	Missense_Mutation	p.P393R	1
EIF4G1	STAD	chr3	184040890	184040890	G	A	Missense_Mutation	p.R657Q	1
EIF4G1	STAD	chr3	184045702	184045702	C	T	Missense_Mutation	p.R1289C	1
EIF4G1	BLCA	chr3	184040229	184040229	C	T	Silent		1
EIF4G1	BLCA	chr3	184043653	184043653	C	T	Missense_Mutation	p.L1047F	1
EIF4G1	MESO	chr3	184044334	184044334	A	G	Missense_Mutation	p.N1082S	1
EIF4G1	PRAD	chr3	184040943	184040943	C	G	Missense_Mutation	p.P668A	1
EIF4G1	ESCA	chr3	184041274	184041274	G	T	Nonsense_Mutation	p.E730X	1
EIF4G1	SARC	chr3	184043279	184043279	G	T	Silent		1
EIF4G1	HNSC	chr3	184045767	184045767	G	-	Frame_Shift_Del	p.L1310fs	1
EIF4G1	SKCM	chr3	184041590	184041590	C	T	Missense_Mutation	p.S767F	1
EIF4G1	COAD	chr3	184041197	184041197	C	T	Missense_Mutation	p.A698V	1
EIF4G1	HNSC	chr3	184049828	184049828	G	T	Silent		1
EIF4G1	HNSC	chr3	184045463	184045463	G	C	Missense_Mutation	p.E1252Q	1
EIF4G1	SKCM	chr3	184040934	184040934	G	A	Missense_Mutation	p.D665N	1
EIF4G1	LIHC	chr3	184039178	184039178	C	-	Frame_Shift_Del	p.S269fs	1
EIF4G1	STAD	chr3	184038434	184038434	C	T	Missense_Mutation	p.P185L	1
EIF4G1	LUAD	chr3	184045040	184045040	A	T	Silent	p.G1156G	1
EIF4G1	THYM	chr3	184046534	184046534	G	T	Nonsense_Mutation	p.E1364X	1
EIF4G1	BLCA	chr3	184049370	184049370	C	G	Missense_Mutation		1
EIF4G1	LUAD	chr3	184049277	184049277	G	C	Silent	p.L1426L	1
EIF4G1	PAAD	chr3	184052556	184052556	G	A	Missense_Mutation	p.V1561M	1
EIF4G1	LUSC	chr3	184043326	184043326	A	G	Missense_Mutation	p.K1007R	1
EIF4G1	PAAD	chr3	184039152	184039152	G	A	Silent	p.S260S	1
EIF4G1	ESCA	chr3	184041274	184041274	G	T	Nonsense_Mutation	p.E730*	1
EIF4G1	HNSC	chr3	184039336	184039336	G	A	Missense_Mutation		1
EIF4G1	HNSC	chr3	184043061	184043061	G	A	Missense_Mutation	p.R955Q	1
EIF4G1	STAD	chr3	184040475	184040475	T	C	Silent	p.A591A	1
EIF4G1	LIHC	chr3	184049876	184049876	T	A	Splice_Site	.	1
EIF4G1	STAD	chr3	184035263	184035263	G	T	Missense_Mutation	p.G108V	1
EIF4G1	LIHC	chr3	184039294	184039294	G	-	Frame_Shift_Del	p.G308fs	1
EIF4G1	STAD	chr3	184043121	184043121	G	A	Missense_Mutation	p.R974H	1
EIF4G1	BLCA	chr3	184045027	184045027	G	A	Missense_Mutation	p.G1152D	1
EIF4G1	CESC	chr3	184045425	184045425	C	G	Missense_Mutation	p.S1245C	1
EIF4G1	STAD	chr3	184039582	184039582	C	T	Missense_Mutation	p.L404F	1
EIF4G1	BLCA	chr3	184043095	184043095	C	A	Silent		1
EIF4G1	BLCA	chr3	184046519	184046519	G	A	Missense_Mutation	p.G1353R	1
EIF4G1	OV	chr3	184041297	184041297	A	G	Silent	p.A730A	1
EIF4G1	PRAD	chr3	184046495	184046496	-	T	Frame_Shift_Ins	p.V1345fs	1
EIF4G1	CHOL	chr3	184039770	184039770	A	G	Silent	p.G473G	1
EIF4G1	ESCA	chr3	184045617	184045617	G	T	Splice_Site	.	1
EIF4G1	HNSC	chr3	184039213	184039213	G	T	Missense_Mutation	p.A281S	1
EIF4G1	KICH	chr3	184038753	184038753	G	A	Silent		1
EIF4G1	SKCM	chr3	184035205	184035205	C	T	Missense_Mutation	p.P82S	1
EIF4G1	COAD	chr3	184041989	184041989	C	T	Silent	p.L826L	1
EIF4G1	HNSC	chr3	184039213	184039213	G	T	Missense_Mutation		1
EIF4G1	HNSC	chr3	184043143	184043143	C	T	Silent	p.D982D	1
EIF4G1	SKCM	chr3	184045627	184045627	C	T	Nonsense_Mutation	p.Q1265X	1
EIF4G1	KIRP	chr3	184052524	184052524	G	A	Missense_Mutation	p.R1550Q	1
EIF4G1	SKCM	chr3	184040958	184040959	-	T	Frame_Shift_Ins	p.W673fs	1
EIF4G1	LIHC	chr3	184039592	184039592	C	-	Frame_Shift_Del	p.A407fs	1
EIF4G1	STAD	chr3	184044360	184044360	C	T	Nonsense_Mutation	p.R1090*	1
EIF4G1	LUAD	chr3	184043403	184043403	G	A	Missense_Mutation	p.G1034S	1
EIF4G1	BLCA	chr3	184035528	184035528	G	T	Silent		1
EIF4G1	LUAD	chr3	184043360	184043360	C	G	Missense_Mutation	p.I1018M	1
EIF4G1	PAAD	chr3	184042077	184042077	A	G	Missense_Mutation	p.D861G	1
EIF4G1	BLCA	chr3	184040478	184040478	G	C	Missense_Mutation	p.E585D	1
EIF4G1	LUSC	chr3	184039636	184039636	G	C	Missense_Mutation	p.E422Q	1
EIF4G1	PAAD	chr3	184042077	184042077	A	G	Missense_Mutation	p.D854G	1
EIF4G1	HNSC	chr3	184045463	184045463	G	C	Missense_Mutation		1
EIF4G1	HNSC	chr3	184046528	184046529	-	T	Frame_Shift_Ins	p.G1356fs	1
EIF4G1	STAD	chr3	184049520	184049520	A	T	Missense_Mutation	p.N1474I	1
EIF4G1	LIHC	chr3	184040633	184040633	A	G	Missense_Mutation	p.E614G	1
EIF4G1	STAD	chr3	184040486	184040486	A	G	Missense_Mutation	p.Q595R	1
EIF4G1	LIHC	chr3	184041229	184041229	C	-	Frame_Shift_Del	p.P709fs	1
EIF4G1	STAD	chr3	184045790	184045790	G	A	Missense_Mutation	p.G1318E	1
EIF4G1	LIHC	chr3	184040633	184040633	A	G	Missense_Mutation	p.E607G	1
EIF4G1	STAD	chr3	184040725	184040725	G	A	Missense_Mutation	p.D638N	1
EIF4G1	LUAD	chr3	184046426	184046426	G	A	Missense_Mutation	p.E1322K	1
EIF4G1	TGCT	chr3	184039304	184039304	A	G	Missense_Mutation		1
EIF4G1	BLCA	chr3	184037587	184037587	A	G	Missense_Mutation		1
EIF4G1	BLCA	chr3	184049736	184049736	G	T	Nonsense_Mutation	p.E1495*	1
EIF4G1	OV	chr3	185535286	185535286	A	G	Missense_Mutation	p.S1566G	1
EIF4G1	READ	chr3	184039767	184039775	AGGAGAAGC	-	In_Frame_Del	p.465_468del	1
EIF4G1	CHOL	chr3	184039769	184039769	G	A	Missense_Mutation	p.G473E	1
EIF4G1	ESCA	chr3	184041019	184041019	C	G	Missense_Mutation	p.P700R	1
EIF4G1	HNSC	chr3	184039214	184039214	C	T	Missense_Mutation	p.A281V	1
EIF4G1	SKCM	chr3	184035526	184035526	C	T	Missense_Mutation	p.P116S	1
EIF4G1	COAD	chr3	184042723	184042723	C	T	Missense_Mutation	p.R894W	1
EIF4G1	HNSC	chr3	184039214	184039214	C	T	Missense_Mutation		1
EIF4G1	HNSC	chr3	184038716	184038716	C	T	Splice_Site	p.T211_splice	1
EIF4G1	SKCM	chr3	184043640	184043640	C	T	Silent	p.S1042S	1
EIF4G1	KIRP	chr3	184035257	184035257	C	T	Missense_Mutation	p.S106F	1
EIF4G1	LIHC	chr3	184040179	184040179	A	-	Frame_Shift_Del	p.K517fs	1
EIF4G1	STAD	chr3	184049755	184049755	A	G	Missense_Mutation	p.D1500G	1
EIF4G1	LUAD	chr3	184049387	184049387	G	T	Missense_Mutation	p.W1464L	1
EIF4G1	UCEC	chr3	184039332	184039332	C	T	Silent	p.L320L	1
EIF4G1	BLCA	chr3	184039844	184039844	T	C	Missense_Mutation		1
EIF4G1	LUAD	chr3	184044714	184044714	C	G	Nonsense_Mutation	p.S1124*	1
EIF4G1	PAAD	chr3	184045152	184045152	C	T	Missense_Mutation	p.R1200W	1
EIF4G1	BLCA	chr3	184035179	184035179	G	A	Missense_Mutation	p.R73H	1
EIF4G1	LUSC	chr3	184038429	184038429	A	T	Silent	p.R183R	1
EIF4G1	PAAD	chr3	184045152	184045152	C	T	Missense_Mutation	p.R1193W	1
EIF4G1	ESCA	chr3	184045115	184045115	T	C	Silent	p.P1187	1
EIF4G1	HNSC	chr3	184038716	184038716	C	T	Missense_Mutation		1
EIF4G1	HNSC	chr3	184045767	184045767	G	-	Frame_Shift_Del	p.L1311fs	1
EIF4G1	LGG	chr3	184040467	184040467	C	T	Missense_Mutation		1
EIF4G1	STAD	chr3	184046703	184046703	T	A	Silent	p.I1369I	1
EIF4G1	LIHC	chr3	184045645	184045645	G	A	Missense_Mutation	p.A1277T	1
EIF4G1	STAD	chr3	184044344	184044344	C	A	Silent	p.L1091L	1
EIF4G1	LIHC	chr3	184041282	184041282	A	-	Frame_Shift_Del	p.I726fs	1
EIF4G1	STAD	chr3	184049780	184049780	G	A	Silent	p.A1508A	1
EIF4G1	LIHC	chr3	184039293	184039294	-	G	Frame_Shift_Ins	p.TG307fs	1
EIF4G1	STAD	chr3	184044344	184044344	C	A	Silent	p.L1084L	1
EIF4G1	LUAD	chr3	184043360	184043360	C	G	Missense_Mutation	p.I1019M	1
EIF4G1	THYM	chr3	184039153	184039153	T	C	Missense_Mutation		1
EIF4G1	BLCA	chr3	184033282	184033282	C	T	Missense_Mutation		1
EIF4G1	BLCA	chr3	184041700	184041700	G	C	Missense_Mutation	p.E803Q	1
EIF4G1	OV	chr3	185527895	185527895	G	C	Missense_Mutation	p.S1209T	1
EIF4G1	READ	chr3	184041257	184041257	C	A	Missense_Mutation	p.A718D	1
EIF4G1	CHOL	chr3	184039802	184039802	A	T	Missense_Mutation	p.E484V	1
EIF4G1	ESCA	chr3	184040221	184040221	C	A	Missense_Mutation	p.L538M	1
EIF4G1	SARC	chr3	184046486	184046486	G	T	Missense_Mutation		1
EIF4G1	KICH	chr3	184035256	184035256	T	C	Missense_Mutation	p.S99P	1
EIF4G1	SKCM	chr3	184041377	184041377	C	T	Missense_Mutation	p.T758I	1
EIF4G1	COAD	chr3	184045394	184045394	C	-	Frame_Shift_Del	p.L1228fs	1
EIF4G1	HNSC	chr3	184046444	184046444	G	A	Missense_Mutation		1
EIF4G1	HNSC	chr3	184043113	184043113	G	A	Silent	p.T972T	1
EIF4G1	KIRP	chr3	184041746	184041746	T	C	Missense_Mutation	p.M819T	1
EIF4G1	STAD	chr3	184044406	184044406	C	A	Missense_Mutation	p.P1105H	1
EIF4G1	LUAD	chr3	184045221	184045221	C	T	Missense_Mutation	p.R1217C	1
EIF4G1	UCEC	chr3	184045418	184045418	G	A	Missense_Mutation	p.A1236T	1
EIF4G1	BLCA	chr3	184039813	184039813	G	C	Missense_Mutation		1
EIF4G1	CESC	chr3	184045064	184045064	G	A	Silent		1
EIF4G1	LUAD	chr3	184049592	184049592	T	A	Missense_Mutation	p.I1491N	1
EIF4G1	PAAD	chr3	184040619	184040619	G	T	Missense_Mutation	p.K609N	1
EIF4G1	ACC	chr3	184049834	184049834	C	T	Silent	p.Y1533Y	1
EIF4G1	BLCA	chr3	184039489	184039489	G	C	Missense_Mutation	p.E373Q	1
EIF4G1	LUSC	chr3	184040983	184040983	G	A	Missense_Mutation	p.R681H	1
EIF4G1	PAAD	chr3	184046477	184046477	C	A	Missense_Mutation	p.L1338I	1
EIF4G1	ESCA	chr3	184045617	184045617	G	T	Splice_Site	e25-1	1
EIF4G1	HNSC	chr3	184043143	184043143	C	T	Silent		1
EIF4G1	HNSC	chr3	184043113	184043113	G	A	Silent	p.T971T	1
EIF4G1	SKCM	chr3	184041648	184041648	G	A	Silent	p.Q786Q	1
EIF4G1	LGG	chr3	184046467	184046467	C	T	Silent		1
EIF4G1	STAD	chr3	184044406	184044406	C	A	Missense_Mutation	p.P1112H	1
EIF4G1	LIHC	chr3	184039489	184039489	G	T	Nonsense_Mutation	p.E380X	1
EIF4G1	STAD	chr3	184039599	184039599	G	A	Silent	p.S416S	1
EIF4G1	LIHC	chr3	184046763	184046763	C	-	Frame_Shift_Del	p.L1384fs	1
EIF4G1	STAD	chr3	184041232	184041232	C	T	Nonsense_Mutation	p.R709*	1
EIF4G1	LIHC	chr3	184039441	184039442	-	A	Frame_Shift_Ins	p.N357fs	1
EIF4G1	STAD	chr3	184039307	184039307	G	A	Missense_Mutation	p.R312H	1
EIF4G1	LUAD	chr3	184040889	184040889	C	T	Missense_Mutation	p.R650W	1
EIF4G1	THYM	chr3	184049793	184049793	A	G	Missense_Mutation		1
EIF4G1	BLCA	chr3	184045027	184045027	G	A	Missense_Mutation		1
EIF4G1	BLCA	chr3	184043095	184043095	C	A	Silent	p.I965I	1
EIF4G1	OV	chr3	185522320	185522320	C	T	Silent	p.V418	1
EIF4G1	READ	chr3	184041658	184041658	G	A	Missense_Mutation	p.D790N	1
EIF4G1	CHOL	chr3	184040641	184040641	A	C	Missense_Mutation	p.K617Q	1
EIF4G1	ESCA	chr3	184045115	184045115	T	C	Silent	p.P1187P	1
EIF4G1	HNSC	chr3	184044414	184044414	G	A	Missense_Mutation	p.A1109T	1
EIF4G1	SARC	chr3	184033870	184033870	T	A	Missense_Mutation		1
EIF4G1	KIRC	chr3	184049133	184049133	G	C	Missense_Mutation	p.G1421A	1
EIF4G1	SKCM	chr3	184039708	184039708	C	T	Missense_Mutation	p.P446S	1
EIF4G1	COAD	chr3	184038427	184038427	C	T	Nonsense_Mutation	p.R183X	1
EIF4G1	HNSC	chr3	184039612	184039612	G	A	Missense_Mutation		1
EIF4G1	HNSC	chr3	184049859	184049859	T	G	Missense_Mutation	p.L1536V	1
EIF4G1	KIRP	chr3	184041746	184041746	T	C	Missense_Mutation	p.M818T	1
EIF4G1	STAD	chr3	184043088	184043088	A	-	Frame_Shift_Del	p.E970fs	1
EIF4G1	LIHC	chr3	184043057	184043057	C	-	Splice_Site	p.P954_splice	1
EIF4G1	STAD	chr3	184035263	184035263	G	T	Missense_Mutation	p.G101V	1
EIF4G1	LUAD	chr3	184052638	184052638	C	T	Missense_Mutation	p.S1582F	1
EIF4G1	BLCA	chr3	184043653	184043653	C	T	Missense_Mutation		1
EIF4G1	LUAD	chr3	184045040	184045040	A	T	Silent	p.G1155G	1
EIF4G1	PAAD	chr3	184046477	184046477	C	A	Missense_Mutation	p.L1345I	1
EIF4G1	ACC	chr3	184042024	184042025	TG	-	Frame_Shift_Del	p.843_843del	1
EIF4G1	BLCA	chr3	184037480	184037480	G	A	Missense_Mutation	p.G143D	1
EIF4G1	LUSC	chr3	184041675	184041675	C	G	Silent	p.L794L	1
EIF4G1	PAAD	chr3	184052556	184052556	G	A	Missense_Mutation	p.V1554M	1
EIF4G1	HNSC	chr3	184043061	184043061	G	A	Missense_Mutation		1
EIF4G1	HNSC	chr3	184046444	184046444	G	A	Missense_Mutation	p.E1327K	1
EIF4G1	SKCM	chr3	184043286	184043286	C	T	Nonsense_Mutation	p.R995*	1
EIF4G1	STAD	chr3	184039307	184039307	G	A	Missense_Mutation	p.R319H	1
EIF4G1	LIHC	chr3	184039824	184039824	C	-	Frame_Shift_Del	p.L491fs	1
EIF4G1	STAD	chr3	184041232	184041232	C	T	Nonsense_Mutation	p.R716X	1
EIF4G1	LIHC	chr3	184049055	184049055	G	A	Missense_Mutation		1
EIF4G1	STAD	chr3	184041274	184041274	G	A	Missense_Mutation	p.E723K	1
EIF4G1	LIHC	chr3	184046513	184046514	-	A	Frame_Shift_Ins	p.R1351fs	1
EIF4G1	STAD	chr3	184040373	184040373	A	G	Silent	p.A550A	1
EIF4G1	THYM	chr3	184042723	184042723	C	T	Missense_Mutation		1
EIF4G1	BLCA	chr3	184035179	184035179	G	A	Missense_Mutation		1
EIF4G1	OV	chr3	184042725	184042725	G	T	Silent	p.R893	1
EIF4G1	READ	chr3	184041734	184041734	C	T	Missense_Mutation	p.A815V	1
EIF4G1	CHOL	chr3	184039802	184039802	A	T	Missense_Mutation	p.E477V	1
EIF4G1	ESCA	chr3	184049760	184049760	G	T	Missense_Mutation		1
EIF4G1	SARC	chr3	184039474	184039474	G	A	Missense_Mutation	p.E368K	1
EIF4G1	KIRC	chr3	184045649	184045649	C	G	Nonsense_Mutation	p.S1278X	1
EIF4G1	SKCM	chr3	184045627	184045627	C	T	Nonsense_Mutation	p.Q1265*	1
EIF4G1	HNSC	chr3	184039136	184039136	C	T	Missense_Mutation		1
EIF4G1	SKCM	chr3	184040958	184040959	-	T	Frame_Shift_Ins	p.L673fs	1
EIF4G1	KIRP	chr3	184041746	184041746	T	C	Missense_Mutation		1
EIF4G1	STAD	chr3	184052538	184052538	G	A	Missense_Mutation	p.A1555T	1
EIF4G1	LIHC	chr3	184043099	184043099	A	-	Frame_Shift_Del	p.K968fs	1
EIF4G1	STAD	chr3	184040486	184040486	A	G	Missense_Mutation	p.Q588R	1
EIF4G1	LUAD	chr3	184049748	184049748	C	T	Nonsense_Mutation	p.R1499*	1
EIF4G1	BLCA	chr3	184046519	184046519	G	A	Missense_Mutation		1
EIF4G1	CESC	chr3	184049281	184049281	G	A	Missense_Mutation	p.E1429K	1
EIF4G1	LUAD	chr3	184043403	184043403	G	A	Missense_Mutation	p.G1033S	1
EIF4G1	BLCA	chr3	184049082	184049082	G	T	Missense_Mutation	p.R1398L	1
EIF4G1	LUSC	chr3	184042714	184042714	A	G	Missense_Mutation	p.I890V	1
EIF4G1	PAAD	chr3	184043334	184043334	G	A	Missense_Mutation	p.E1010K	1
EIF4G1	ESCA	chr3	184032427	184032427	G	A	Missense_Mutation		1
EIF4G1	HNSC	chr3	184049859	184049859	T	G	Missense_Mutation		1
EIF4G1	HNSC	chr3	184043060	184043060	C	T	Nonsense_Mutation	p.R954*	1
EIF4G1	SKCM	chr3	184043640	184043640	C	T	Splice_Site	p.S1042_splice	1
EIF4G1	LIHC	chr3	184040193	184040193	A	-	Frame_Shift_Del	p.L528fs	1
EIF4G1	STAD	chr3	184038434	184038434	C	T	Missense_Mutation	p.P192L	1
EIF4G1	LUAD	chr3	184045208	184045208	G	T	Silent	p.T1212T	1
EIF4G1	STAD	chr3	184042726	184042726	C	T	Missense_Mutation	p.R894C	1
EIF4G1	STAD	chr3	184045694	184045694	C	T	Missense_Mutation	p.T1286M	1
EIF4G1	THYM	chr3	184038488	184038488	C	T	Missense_Mutation		1
EIF4G1	PAAD	chr3	184039075	184039075	C	T	Missense_Mutation		1
EIF4G1	READ	chr3	184042879	184042879	G	T	Missense_Mutation	p.D946Y	1
EIF4G1	CHOL	chr3	184040641	184040641	A	C	Missense_Mutation	p.K610Q	1
EIF4G1	GBM	chr3	184052651	184052651	C	G	Missense_Mutation	p.F1585L	1
EIF4G1	SARC	chr3	184039474	184039474	G	A	Missense_Mutation	p.E375K	1
EIF4G1	KIRC	chr3	184049812	184049812	A	G	Missense_Mutation	p.Q1526R	1
EIF4G1	SKCM	chr3	184039151	184039151	C	T	Missense_Mutation	p.S260L	1

Copy number variation (CNV) of EIF4G1
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across EIF4G1
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
38186	BRCA	TCGA-AN-A0FJ-01A	EIF4G1	chr3	184052622	+	ABCF3	chr3	183910890	+
78571	SKCM	TCGA-BF-A3DJ-01A	EIF4G1	chr3	184045091	-	AEBP1	chr7	44143960	+
102890	KIRP	TCGA-BQ-5879-01A	EIF4G1	chr3	184053139	-	ANKS1A	chr6	34977682	+
69680	LUSC	TCGA-43-7656	EIF4G1	chr3	184039450	+	ECE2	chr3	184008185	+
69680	LUSC	TCGA-43-7656-01A	EIF4G1	chr3	184039449	+	ECE2	chr3	184008184	+
69680	LUSC	TCGA-43-7656-01A	EIF4G1	chr3	184039451	+	ECE2	chr3	184008339	+
99948	N/A	AU133771	EIF4G1	chr3	184040965	+	EIF4G1	chr3	184038480	+
99948	N/A	BF734084	EIF4G1	chr3	184045002	-	EIF4G1	chr3	184039685	+
99948	N/A	BQ212371	EIF4G1	chr3	184043088	+	EIF4G1	chr3	184042116	+
99948	N/A	DA453269	EIF4G1	chr3	184037517	+	EIF4G1	chr3	184033920	+
89200	N/A	BE077006	EIF4G1	chr3	184052077	-	HELLS	chr10	96326248	-
99367	N/A	AX260875	EIF4G1	chr3	184043106	+	HIPK3	chr11	33339779	-
76922	N/A	BQ009628	EIF4G1	chr3	184052945	-	MCC	chr5	112389659	-
96244	COAD	TCGA-AA-A00J-01A	EIF4G1	chr3	184052769	+	NCOR2	chr12	124824735	-
62686	PRAD	TCGA-KK-A6DY-01A	EIF4G1	chr3	184046778	+	PTH2R	chr2	209688919	+
102406	LUAD	TCGA-78-7158-01A	EIF4G1	chr3	184053139	-	SNW1	chr14	78189203	-
87157	N/A	CB049564	EIF4G1	chr3	184041221	+	STARD10	chr11	72465805	-
93372	N/A	AW859452	EIF4G1	chr3	184040401	+	TPM2	chr9	35685776	-
103080	N/A	BM986898	EIF4G1	chr3	184053141	+	TTC28	chr22	28837876	+
99948	N/A	EC577200	FRMD6	chr14	52013666	+	EIF4G1	chr3	184053141	-
99948	N/A	DA536097	MYO18A	chr17	27435487	-	EIF4G1	chr3	184043146	+
99948	N/A	AI744700	PPP1R14A	chr19	38742046	+	EIF4G1	chr3	184049153	-
99948	PRAD	TCGA-EJ-A7NJ-01A	PTMS	chr12	6880118	-	EIF4G1	chr3	184042892	+
99948	N/A	AI205494	RABEP1	chr17	5281981	+	EIF4G1	chr3	184040202	-
99948	N/A	AK098133	RAP1A	chr1	112196322	+	EIF4G1	chr3	184045905	+
99948	N/A	BF696853	RNU6-3P	chrX	140212209	-	EIF4G1	chr3	184038425	+
99948	N/A	CF142008	STX8	chr17	9221087	-	EIF4G1	chr3	184052994	+
99948	PRAD	TCGA-HC-7213-01A	TLN1	chr9	35697334	-	EIF4G1	chr3	184042892	+
99948	Non-Cancer	ERR315342	TNS1	chr2	218712721	-	EIF4G1	chr3	184044388	+
99948	N/A	F00479	TTN-AS1	chr2	179484504	+	EIF4G1	chr3	184049086	-
99948	N/A	BQ016901	UCP2	chr11	73685963	+	EIF4G1	chr3	184045158	+
99948	THCA	TCGA-EL-A3H3	VPS8	chr3	184530013	+	EIF4G1	chr3	184049053	+
99948	THCA	TCGA-EL-A3H3-01A	VPS8	chr3	184530013	+	EIF4G1	chr3	184049054	+
99967	BRCA	TCGA-A2-A04U-01A	YEATS2	chr3	183472153	+	EIF4G1	chr3	184052515	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LIHC	EIF4G1	0.00248998636747212	0.07
KIRC	EIF4G1	0.0155859491315415	0.42
LUAD	EIF4G1	0.0234166163671849	0.61
LAML	EIF4G1	0.0474756033779774	1

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
BRCA	EIF4G1	0.0373199922848767	1
OV	EIF4G1	0.00235269718364308	0.073
UCEC	EIF4G1	0.0168443423880405	0.49
UCS	EIF4G1	0.0016432854045515	0.053
ESCA	EIF4G1	0.00059341400581404	0.02
THYM	EIF4G1	0.0125558090355476	0.38

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C3280271	PARKINSON DISEASE 18	3	CTD_human;GENOMICS_ENGLAND;UNIPROT