Home

Download

Statistics

Examples

Help

Contact

	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: MRPS28 (NCBI Gene ID:28957)

Gene Summary

Gene Summary

Gene Information	Gene Name: MRPS28
	Gene ID: 28957
	Gene Symbol	MRPS28
	Gene ID	28957
	Gene Name	mitochondrial ribosomal protein S28
	Synonyms	HSPC007\|MRP-S28\|MRP-S35\|MRPS35
	Cytomap	8q21.13
	Type of Gene	protein-coding
	Description	28S ribosomal protein S28, mitochondrial28S ribosomal protein S35, mitochondrialS28mtS35mtmitochondrial 28S ribosomal protein S35mitochondrial small ribosomal subunit protein bS1m
	Modification date	20200315
	UniProtAcc	Q9Y2Q9

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0032543	Mitochondrial translation
GO:0005840	Ribosome
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene

Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25

Top

Translation Studies in PubMed

We searched PubMed using 'MRPS28[title] AND translation [title] AND human.'

Gene	Title	PMID
MRPS28	.	.

Top

Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

ORF

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

Top

Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
LUSC	MRPS28	-1.73946088864532	0.000778331171335384
LUAD	MRPS28	-1.30551207360684	0.00627490756378455

Top

Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type

Gene

Coefficient

Pvalue

Top

Associated Genes

Strongly correlated genes belong to cellular important gene groups with MRPS28 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
CHOL	Cell metabolism gene	MRPS28	SCP2	0.804015584	2.91E-11
CHOL	Cell metabolism gene	MRPS28	SUOX	0.805647512	2.48E-11
CHOL	Cell metabolism gene	MRPS28	SLC25A13	0.807608142	2.03E-11
CHOL	Cell metabolism gene	MRPS28	ETNK2	0.809650712	1.65E-11
CHOL	Cell metabolism gene	MRPS28	ALDH5A1	0.812283016	1.26E-11
CHOL	Cell metabolism gene	MRPS28	CAT	0.813989775	1.05E-11
CHOL	Cell metabolism gene	MRPS28	ALDH7A1	0.820125204	5.47E-12
CHOL	Cell metabolism gene	MRPS28	AK3	0.820431848	5.29E-12
CHOL	Cell metabolism gene	MRPS28	DECR1	0.82523746	3.11E-12
CHOL	Cell metabolism gene	MRPS28	ADH7	0.826169804	2.80E-12
CHOL	Cell metabolism gene	MRPS28	HIBCH	0.836246701	8.63E-13
CHOL	Cell metabolism gene	MRPS28	PEX11A	0.839783211	5.60E-13
CHOL	Cell metabolism gene	MRPS28	GLUD1	0.854942832	7.75E-14
CHOL	IUPHAR	MRPS28	SLC25A13	0.807608142	2.03E-11
CHOL	IUPHAR	MRPS28	ALDH5A1	0.812283016	1.26E-11
CHOL	IUPHAR	MRPS28	CAT	0.813989775	1.05E-11
CHOL	TSG	MRPS28	CAT	0.813989775	1.05E-11
DLBC	Cell metabolism gene	MRPS28	SNRPD3	0.80181763	7.47E-12
DLBC	Cell metabolism gene	MRPS28	TOMM22	0.802997396	6.60E-12
DLBC	Cell metabolism gene	MRPS28	ADSL	0.806086056	4.75E-12
GBM	Cell metabolism gene	MRPS28	SUCLG1	0.824339637	7.25E-44
UVM	Cell metabolism gene	MRPS28	GFPT1	0.80056221	5.03E-19
UVM	Cell metabolism gene	MRPS28	RRM2B	0.80633507	1.80E-19
UVM	Cell metabolism gene	MRPS28	CALM2	0.809704133	9.72E-20
UVM	Cell metabolism gene	MRPS28	ALG5	0.81361513	4.68E-20
UVM	Cell metabolism gene	MRPS28	RAP1B	0.814147337	4.24E-20
UVM	Cell metabolism gene	MRPS28	PIK3C2A	0.821071537	1.11E-20
UVM	Cell metabolism gene	MRPS28	PSMD12	0.822179375	8.90E-21
UVM	Cell metabolism gene	MRPS28	MDH1	0.83009388	1.77E-21
UVM	Cell metabolism gene	MRPS28	TIMM17A	0.834527409	6.89E-22
UVM	Cell metabolism gene	MRPS28	PSMA4	0.834955242	6.29E-22
UVM	Cell metabolism gene	MRPS28	PSME4	0.850001569	2.04E-23
UVM	Cell metabolism gene	MRPS28	SAR1B	0.850193641	1.95E-23
UVM	Cell metabolism gene	MRPS28	PSMA3	0.852299029	1.17E-23
UVM	Cell metabolism gene	MRPS28	PSMC2	0.853991555	7.73E-24
UVM	Cell metabolism gene	MRPS28	PSMA6	0.85572983	5.01E-24
UVM	Cell metabolism gene	MRPS28	LYPLA1	0.864956323	4.57E-25
UVM	Cell metabolism gene	MRPS28	AZIN1	0.868192292	1.89E-25
UVM	Cell metabolism gene	MRPS28	PSMD14	0.870262608	1.06E-25
UVM	Cell metabolism gene	MRPS28	TGS1	0.875149794	2.62E-26
UVM	Cell metabolism gene	MRPS28	YWHAZ	0.894507093	5.37E-29
UVM	Cell metabolism gene	MRPS28	SLC25A32	0.903873277	1.71E-30
UVM	Cell metabolism gene	MRPS28	IMPA1	0.907878424	3.52E-31
UVM	Cell metabolism gene	MRPS28	POLR2K	0.910866362	1.03E-31
UVM	Cell metabolism gene	MRPS28	TRAM1	0.931332716	5.84E-36
UVM	CGC	MRPS28	RAD21	0.837844701	3.35E-22
UVM	CGC	MRPS28	NBN	0.859128789	2.12E-24
UVM	CGC	MRPS28	UBR5	0.860003584	1.69E-24
UVM	CGC	MRPS28	TCEA1	0.914647184	2.05E-32
UVM	Epifactor	MRPS28	RAD54B	0.802739261	3.43E-19
UVM	Epifactor	MRPS28	ATAD2	0.805312976	2.16E-19
UVM	Epifactor	MRPS28	PHF20L1	0.823240251	7.20E-21
UVM	Epifactor	MRPS28	NBN	0.859128789	2.12E-24
UVM	Epifactor	MRPS28	UBR5	0.860003584	1.69E-24
UVM	Epifactor	MRPS28	TAF2	0.867307683	2.42E-25
UVM	Epifactor	MRPS28	ENY2	0.883723935	1.93E-27
UVM	Epifactor	MRPS28	YWHAZ	0.894507093	5.37E-29
UVM	IUPHAR	MRPS28	ATAD2	0.805312976	2.16E-19
UVM	IUPHAR	MRPS28	TMEM165	0.805727104	2.01E-19
UVM	IUPHAR	MRPS28	RRM2B	0.80633507	1.80E-19
UVM	IUPHAR	MRPS28	PIK3C2A	0.821071537	1.11E-20
UVM	IUPHAR	MRPS28	PTK2	0.833315055	8.94E-22
UVM	IUPHAR	MRPS28	CYP51A1	0.861491844	1.15E-24
UVM	IUPHAR	MRPS28	STK3	0.864770179	4.81E-25
UVM	IUPHAR	MRPS28	PSMD14	0.870262608	1.06E-25
UVM	IUPHAR	MRPS28	NSMAF	0.873345433	4.43E-26
UVM	IUPHAR	MRPS28	ATP6V1C1	0.887235675	6.27E-28
UVM	IUPHAR	MRPS28	SLC25A32	0.903873277	1.71E-30
UVM	IUPHAR	MRPS28	IMPA1	0.907878424	3.52E-31
UVM	IUPHAR	MRPS28	ATP6V1H	0.914636901	2.06E-32
UVM	Kinase	MRPS28	PTK2	0.833315055	8.94E-22
UVM	Kinase	MRPS28	STK3	0.864770179	4.81E-25
UVM	TF	MRPS28	E2F5	0.8334695	8.65E-22
UVM	TF	MRPS28	TERF1	0.87543656	2.41E-26
UVM	TSG	MRPS28	NBN	0.859128789	2.12E-24

Top

Protein structure

Protein 3D structure
Visit iCn3D.

Top

Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
BRCA	MRPS28	MRPS27	-2.1331392862776	0.000127527962379903
BRCA	MRPS28	MRPS15	-2.19567551682318	0.000188684660674703
STAD	MRPS28	PTCD3	-1.34538483750672	0.00256496202200651
THCA	MRPS28	MRPS34	-1.45441957963461	0.00290442341112608
KIRC	MRPS28	MRPS15	1.11572283836012	0.00361818577801855
PRAD	MRPS28	MRPS9	1.04379115553269	0.00496210155254694
KICH	MRPS28	MRPS2	1.26543989555015	0.0114533305168152
THCA	MRPS28	MRPS15	-1.19960602422995	0.0140154883942907
ESCA	MRPS28	MRPS2	-3.20556788084675	0.0244140625
PRAD	MRPS28	MRPS34	-5.35106598630245	0.0285087588592711
READ	MRPS28	PTCD3	2.94667594287193	0.03125
HNSC	MRPS28	PTCD3	1.11617967730562	0.0372559385364731
KICH	MRPS28	MRPS22	1.59345779884986	0.0451226830482483
LUSC	MRPS28	MRPS9	-3.60637641031661	1.82498668910368e-07
LUSC	MRPS28	MRPS2	-2.70930846488508	1.92864354932136e-09
LUAD	MRPS28	MRPS9	-1.32894454884901	1.98978698949574e-05
LUAD	MRPS28	MRPS34	-2.70136571593428	2.07702654013452e-08
LUAD	MRPS28	MRPS27	-2.46461120873599	2.13247131179291e-05
LUAD	MRPS28	MRPL42	-6.34610249602491	2.48255276366547e-08
LUSC	MRPS28	MRPS26	-3.32725244934649	2.86720468728312e-07
BRCA	MRPS28	MRPS34	-2.53214434739385	3.14738496193661e-22
LUSC	MRPS28	PTCD3	-2.41729475275087	3.25673250216465e-06
LIHC	MRPS28	MRPS2	-1.14771055358828	4.2584580238307e-05
LUSC	MRPS28	MRPS34	-2.71852874741784	4.28240904037329e-08
THCA	MRPS28	PTCD3	1.09980719703362	4.34082003868401e-07
KIRC	MRPS28	MRPL42	-4.382095336248	5.26630854166927e-06

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with MRPS28

ICT1, CAND1, MRPL32, MRPL13, MRPL53, MRPL41, MRPS26, MRPS9, MRPL12, MRPS18B, MRPL42, SCP2, CDV3, SRPRB, TIAL1, HNRNPU, ILF2, NDUFA7, NPC1, NDUFB6, HNRNPM, RBM27, RPS28, HNRNPR, SLC25A10, PQBP1, NDUFB9, RPS19, MDH2, ABCC2, SYNCRIP, FN1, C1QBP, rev, PARK2, GRSF1, TP53, TUBGCP3, FBXW11, MRPS2, TRMT10B, MRPS31, HNRNPA1, MRPS22, MRPS27, DAP3, PTCD3, HIST1H3E, ERBB3, ZNF746, CDC14B, PTP4A1, MRPS34, MRPS15, MRPS11, RBM3, CFAP20, LEO1, MRPL37, MRPS14, GATB, SNRPG, EFTUD2, TNIP2, SPDL1, HEXIM1, MEPCE, LARP7, RECQL4, MB21D1, MYC, AIFM1, MRM1, HSPD1, TRMT61B, AURKAIP1, GRWD1, USP14, ALYREF, SNRNP70, ITFG1, CLUAP1, SQSTM1, CCDC8, OBSL1, CUL9, PTEN, PTPRR, SOCS1, NME1-NME2, FLT3, E, CELF1, PRRC2A, ZC3HAV1, IGF2BP1, KIF14, FGD2, ARHGAP27, ARHGAP36, DOCK8, ACAD9, AUH, C12orf65, C17orf80, C21orf33, C6orf203, C8orf82, MCUR1, CCDC90B, CHCHD1, COX15, CRYZ, CS, DDX28, DHX30, FASTKD2, FASTKD3, FASTKD5, GFM1, GFM2, HINT2, LONP1, LRPPRC, MCU, CCDC109B, METTL15, METTL17, MRPL11, MRPS12, MRRF, MTERF3, MTFMT, MTG1, MTG2, MTIF2, MTIF3, MTRF1, MTRF1L, NGRN, OTC, PMPCA, PMPCB, RMND1, RPUSD3, RPUSD4, SLIRP, SSBP1, SURF1, TACO1, TBRG4, TEFM, TFAM, TMEM70, TRUB2, TSFM, TUFM, VWA8, EXD2, ORF4a, CLPP, MAFB, DNAJC15, DNAJC19, HSCB, AMOT, AMOTL1, MRPS24, MRPS23, MRPS10, MRPS35, YPEL5, DYNLL1, WDR70, ATP5J2, UFL1, DDRGK1, AARS2, COX4I1, COX8A, LAMTOR1, PDHA1, TRAP1, FZR1, MAP4K3, ZBTB2, RPS9, RBMS2, MRPS17, KBTBD7, H2AFB3, MRPS18C, GLI4, UTP23, SRSF3, PRR3, YBX1, MRPS25, H1FNT, NEIL1, MCAT, SRSF7, KLF12, TLX2, KLF15, KLF4, TLX1,

Top

Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
MRPS28	BLCA	chr8	80942405	80942405	G	A	Missense_Mutation		3
MRPS28	BLCA	chr8	80942405	80942405	G	A	Missense_Mutation	p.R27W	2
MRPS28	UCEC	chr8	80831266	80831266	T	A	Silent	p.G171	2
MRPS28	CESC	chr8	80831357	80831357	C	T	Missense_Mutation		2
MRPS28	SKCM	chr8	80831226	80831226	G	A	Missense_Mutation	p.H185Y	2
MRPS28	LIHC	chr8	80942420	80942420	A	G	Missense_Mutation		2
MRPS28	ESCA	chr8	80942328	80942328	G	A	Silent	p.F52F	2
MRPS28	LUAD	chr8	80831369	80831369	C	A	Missense_Mutation	p.G137V	2
MRPS28	HNSC	chr8	80915385	80915385	A	G	Missense_Mutation	p.S82P	1
MRPS28	LUSC	chr8	80942390	80942390	C	A	Nonsense_Mutation	p.E32*	1
MRPS28	THCA	chr8	80942299	80942299	A	G	Missense_Mutation		1
MRPS28	KIRP	chr8	80942421	80942421	G	T	Silent		1
MRPS28	LUSC	chr8	80831357	80831357	C	T	Missense_Mutation	p.R141Q	1
MRPS28	BLCA	chr8	80942415	80942415	G	A	Silent	p.F23F	1
MRPS28	UCEC	chr8	80831266	80831266	T	A	Silent	p.G171G	1
MRPS28	LGG	chr8	80831363	80831363	C	A	Missense_Mutation	p.R139M	1
MRPS28	PRAD	chr8	80831351	80831351	C	T	Missense_Mutation	p.R143Q	1
MRPS28	CESC	chr8	80942341	80942341	C	G	Missense_Mutation		1
MRPS28	LGG	chr8	80831363	80831363	C	A	Missense_Mutation		1
MRPS28	READ	chr8	80942405	80942405	G	T	Silent	p.R27R	1
MRPS28	LGG	chr8	80942402	80942402	C	A	Missense_Mutation		1
MRPS28	COAD	chr8	80915322	80915322	G	A	Missense_Mutation	p.R103W	1
MRPS28	SKCM	chr8	80831334	80831334	G	A	Missense_Mutation	p.L149F	1
MRPS28	ESCA	chr8	80942328	80942328	G	A	Silent		1
MRPS28	LIHC	chr8	80942312	80942312	G	T	Silent	p.R58R	1
MRPS28	STAD	chr8	80942415	80942417	GAA	-	In_Frame_Del	p.23_24del	1
MRPS28	LIHC	chr8	80942420	80942420	A	G	Missense_Mutation	p.F22L	1
MRPS28	BLCA	chr8	80942390	80942390	C	T	Missense_Mutation		1
MRPS28	STAD	chr8	80915402	80915402	T	-	Frame_Shift_Del	p.N76fs	1
MRPS28	HNSC	chr8	80915385	80915385	A	G	Missense_Mutation		1
MRPS28	STAD	chr8	80942415	80942417	GAA	-	In_Frame_Del	p.F23del	1
MRPS28	HNSC	chr8	80942442	80942442	G	T	Missense_Mutation		1
MRPS28	LUAD	chr8	80942443	80942443	C	A	Missense_Mutation	p.S14I	1
MRPS28	BLCA	chr8	80942415	80942415	G	A	Silent		1
MRPS28	STAD	chr8	80942415	80942417	GAA	-	In_Frame_Del	p.23_24FR>*	1
MRPS28	HNSC	chr8	80942442	80942442	G	T	Missense_Mutation	p.S14R	1
MRPS28	LUAD	chr8	80942275	80942275	T	C	Missense_Mutation	p.Q70R	1
MRPS28	BLCA	chr8	80915324	80915324	C	T	Missense_Mutation		1
MRPS28	THCA	chr8	80942298	80942298	A	G	Silent		1

Copy number variation (CNV) of MRPS28
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across MRPS28
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
95518	STAD	TCGA-RD-A7BW	CDH11	chr16	65087706	-	MRPS28	chr8	80915415	-
95518	HNSC	TCGA-BA-6868-01B	MAMDC2	chr9	72746528	+	MRPS28	chr8	80831383	-
91852	N/A	BP350832	MRPS28	chr8	80915234	-	ARFGEF1	chr8	68214701	-
100209	BRCA	TCGA-E2-A1B0-01A	MRPS28	chr8	80915234	-	AZIN1	chr8	103899375	-
96875	BRCA	TCGA-C8-A134-01A	MRPS28	chr8	80915234	-	HIST1H2AC	chr6	26138282	+
84019	HNSC	TCGA-BA-6868-01B	MRPS28	chr8	80915234	-	MAMDC2	chr9	72723127	+
99783	SKCM	TCGA-FS-A1ZZ-06A	MRPS28	chr8	80915234	-	NKAIN3	chr8	63877913	+
82722	BRCA	TCGA-D8-A1XQ-01A	MRPS28	chr8	80915234	-	POGZ	chr1	151414681	-
95518	Non-Cancer	TCGA-CG-5730-11A	MTDH	chr8	98657115	+	MRPS28	chr8	80915415	-
95518	COAD	TCGA-A6-3807	OXR1	chr8	107696587	+	MRPS28	chr8	80831383	-
95518	SKCM	TCGA-FS-A1ZZ-06A	SEC22C	chr3	42623338	-	MRPS28	chr8	80831383	-
95518	SKCM	TCGA-FS-A1ZZ-06A	SEC22C	chr3	42623685	-	MRPS28	chr8	80831383	-
95518	BLCA	TCGA-2F-A9KO-01A	TPD52	chr8	80950355	-	MRPS28	chr8	80831383	-
95518	BLCA	TCGA-CF-A1HS-01A	TPD52	chr8	80954854	-	MRPS28	chr8	80831382	-
95518	BLCA	TCGA-HQ-A2OF-01A	TPD52	chr8	81083660	-	MRPS28	chr8	80831383	-
95518	BRCA	TCGA-BH-A204-01A	TPD52	chr8	80963762	-	MRPS28	chr8	80831383	-
95518	BRCA	TCGA-D8-A1JL-01A	TPD52	chr8	80954857	-	MRPS28	chr8	80831385	-
95518	CESC	TCGA-R2-A69V-01A	TPD52	chr8	80976713	-	MRPS28	chr8	80831383	-
95520	N/A	FN158775	TXLNB	chr6	139637037	-	MRPS28	chr8	80890902	-

Top

Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

Top

Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KICH	MRPS28	0.030055978925673	0.81
LUAD	MRPS28	0.0326009630902929	0.85
TGCT	MRPS28	0.0384343516800846	0.96
LAML	MRPS28	0.0394302405011177	0.96
LIHC	MRPS28	1.46028313045339e-09	4.1e-08

Top

Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUSC	MRPS28	0.0149025867119842	0.46
BRCA	MRPS28	1.9800882724903e-05	0.00065
PRAD	MRPS28	0.0182612212209967	0.55
ESCA	MRPS28	0.00854345611436148	0.27

Top

Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C0006142	Malignant neoplasm of breast	1	CTD_human
C0678222	Breast Carcinoma	1	CTD_human
C1257931	Mammary Neoplasms, Human	1	CTD_human
C4704874	Mammary Carcinoma, Human	1	CTD_human