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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: DHX29 (NCBI Gene ID:54505)

Gene Summary

Gene Summary

Gene Information	Gene Name: DHX29
	Gene ID: 54505
	Gene Symbol	DHX29
	Gene ID	54505
	Gene Name	DExH-box helicase 29
	Synonyms	DDX29
	Cytomap	5q11.2
	Type of Gene	protein-coding
	Description	ATP-dependent RNA helicase DHX29DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29DEAH (Asp-Glu-Ala-His) box polypeptide 29DEAH box protein 29DEAH-box helicase 29nucleic acid helicase DDXx
	Modification date	20200320
	UniProtAcc	Q7Z478

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0006417	Regulation of translation
GO:0008135	Translation factor activity, RNA binding
GO:0005840	Ribosome
GO:0045727	Positive regulation of translation
GO:0002181	Cytoplasmic translation
GO:0006413	Translational initiation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
DHX29	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'DHX29[title] AND translation [title] AND human.'

Gene	Title	PMID
DHX29	DHX29 and eIF3 cooperate in ribosomal scanning on structured mRNAs during translation initiation	27733651

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000251636	54555675	54555772	Frame-shift
ENST00000251636	54557195	54557327	In-frame
ENST00000251636	54558457	54558760	In-frame
ENST00000251636	54569120	54569205	Frame-shift
ENST00000251636	54581523	54581689	Frame-shift

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000251636	54557195	54557327	4519	3978	4109	1369	1276	1320
ENST00000251636	54558457	54558760	4519	3675	3977	1369	1175	1276

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc	Exon skip start (AA)	Exon Skip end (AA)	Function feature start (AA)	Function feature end (AA)	Functional feature type	Functional feature desc.
Q7Z478	1276	1320	1	1369	Chain	ID=PRO_0000245535;Note=ATP-dependent RNA helicase DHX29
Q7Z478	1175	1276	1	1369	Chain	ID=PRO_0000245535;Note=ATP-dependent RNA helicase DHX29

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
HNSC	DHX29	-1.35997500354731	0.00389513226355121
KIRC	DHX29	-2.50311015175691	1.2425209135086e-09
THCA	DHX29	-5.17947337249536	1.45093935958224e-09

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
UCS	DHX29	0.074844516	0.007264173
KICH	DHX29	0.054557826	0.023219421
CHOL	DHX29	-0.080622133	0.046357556

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with DHX29 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
DLBC	Cell metabolism gene	DHX29	GNE	0.801739665	7.53E-12
DLBC	Cell metabolism gene	DHX29	PATL1	0.805273432	5.18E-12
DLBC	Cell metabolism gene	DHX29	LONP2	0.806649854	4.48E-12
DLBC	Cell metabolism gene	DHX29	CANX	0.808558284	3.64E-12
DLBC	Cell metabolism gene	DHX29	POLR3A	0.809642384	3.24E-12
DLBC	Cell metabolism gene	DHX29	EP300	0.810552133	2.93E-12
DLBC	Cell metabolism gene	DHX29	IPMK	0.812167989	2.45E-12
DLBC	Cell metabolism gene	DHX29	PRKAR2A	0.815223167	1.74E-12
DLBC	Cell metabolism gene	DHX29	TNPO1	0.81846719	1.20E-12
DLBC	CGC	DHX29	EP300	0.810552133	2.93E-12
DLBC	CGC	DHX29	TOP1	0.81764267	1.32E-12
DLBC	CGC	DHX29	N4BP2	0.818553066	1.19E-12
DLBC	CGC	DHX29	STRN	0.824978066	5.59E-13
DLBC	CGC	DHX29	LATS1	0.830522981	2.84E-13
DLBC	CGC	DHX29	ASXL2	0.834632523	1.69E-13
DLBC	CGC	DHX29	NUP98	0.847850488	2.90E-14
DLBC	Epifactor	DHX29	REST	0.803183516	6.47E-12
DLBC	Epifactor	DHX29	CHD8	0.806547189	4.52E-12
DLBC	Epifactor	DHX29	TAF2	0.807116692	4.26E-12
DLBC	Epifactor	DHX29	GTF3C4	0.808880195	3.52E-12
DLBC	Epifactor	DHX29	EP300	0.810552133	2.93E-12
DLBC	Epifactor	DHX29	USP12	0.813543569	2.10E-12
DLBC	Epifactor	DHX29	IKZF3	0.817387378	1.36E-12
DLBC	Epifactor	DHX29	ASXL2	0.834632523	1.69E-13
DLBC	IUPHAR	DHX29	LMTK2	0.808203517	3.78E-12
DLBC	IUPHAR	DHX29	GTF3C4	0.808880195	3.52E-12
DLBC	IUPHAR	DHX29	EP300	0.810552133	2.93E-12
DLBC	IUPHAR	DHX29	PRKAR2A	0.815223167	1.74E-12
DLBC	IUPHAR	DHX29	TOP1	0.81764267	1.32E-12
DLBC	IUPHAR	DHX29	DPP8	0.824086969	6.22E-13
DLBC	IUPHAR	DHX29	HIPK3	0.826810489	4.48E-13
DLBC	IUPHAR	DHX29	LATS1	0.830522981	2.84E-13
DLBC	IUPHAR	DHX29	ATP2A2	0.839961417	8.47E-14
DLBC	Kinase	DHX29	LMTK2	0.808203517	3.78E-12
DLBC	Kinase	DHX29	HIPK3	0.826810489	4.48E-13
DLBC	Kinase	DHX29	LATS1	0.830522981	2.84E-13
DLBC	TF	DHX29	REST	0.803183516	6.47E-12
DLBC	TF	DHX29	TOPORS	0.809818171	3.17E-12
DLBC	TF	DHX29	IKZF3	0.817387378	1.36E-12
DLBC	TF	DHX29	ETV3	0.828177725	3.80E-13
DLBC	TF	DHX29	ZNF281	0.855283421	9.96E-15
DLBC	TSG	DHX29	TOPORS	0.809818171	3.17E-12
DLBC	TSG	DHX29	USP12	0.813543569	2.10E-12
DLBC	TSG	DHX29	IKZF3	0.817387378	1.36E-12
DLBC	TSG	DHX29	LATS1	0.830522981	2.84E-13
DLBC	TSG	DHX29	NUP98	0.847850488	2.90E-14
KIRP	Cell metabolism gene	DHX29	PHAX	0.806706126	2.57E-75
PCPG	Cell metabolism gene	DHX29	PHAX	0.804347025	1.08E-43
SKCM	IUPHAR	DHX29	SLC30A5	0.809950194	1.90E-111
SKCM	TF	DHX29	GPBP1	0.819869146	2.18E-116
THCA	Cell metabolism gene	DHX29	PPM1L	0.800062832	1.35E-128
THCA	Cell metabolism gene	DHX29	HSD17B4	0.801401813	2.46E-129
THCA	Cell metabolism gene	DHX29	PHKB	0.802636527	5.06E-130
THCA	Cell metabolism gene	DHX29	HMGCR	0.822727072	5.98E-142
THCA	IUPHAR	DHX29	HMGCR	0.822727072	5.98E-142
THCA	TSG	DHX29	PPM1L	0.800062832	1.35E-128
THYM	Cell metabolism gene	DHX29	L2HGDH	0.803110658	9.32E-29
THYM	Cell metabolism gene	DHX29	HSPA9	0.814557418	3.69E-30
THYM	Cell metabolism gene	DHX29	HIF1A	0.86998633	1.18E-38
THYM	CGC	DHX29	HIF1A	0.86998633	1.18E-38
THYM	IUPHAR	DHX29	ATP2C1	0.817257299	1.67E-30
THYM	IUPHAR	DHX29	PTPN1	0.819178671	9.42E-31
THYM	IUPHAR	DHX29	CSNK1A1	0.828584663	5.14E-32
THYM	Kinase	DHX29	CSNK1A1	0.828584663	5.14E-32
THYM	TF	DHX29	ZBTB41	0.825664184	1.29E-31
THYM	TF	DHX29	HIF1A	0.86998633	1.18E-38
THYM	TSG	DHX29	ANXA7	0.805696439	4.58E-29
THYM	TSG	DHX29	PTPN1	0.819178671	9.42E-31
THYM	TSG	DHX29	CSNK1A1	0.828584663	5.14E-32
THYM	TSG	DHX29	HIF1A	0.86998633	1.18E-38
UCS	Cell metabolism gene	DHX29	L2HGDH	0.803110658	9.32E-29
UCS	Cell metabolism gene	DHX29	HSPA9	0.814557418	3.69E-30
UCS	Cell metabolism gene	DHX29	HIF1A	0.86998633	1.18E-38
UCS	CGC	DHX29	HIF1A	0.86998633	1.18E-38
UCS	IUPHAR	DHX29	ATP2C1	0.817257299	1.67E-30
UCS	IUPHAR	DHX29	PTPN1	0.819178671	9.42E-31
UCS	IUPHAR	DHX29	CSNK1A1	0.828584663	5.14E-32
UCS	Kinase	DHX29	CSNK1A1	0.828584663	5.14E-32
UCS	TF	DHX29	ZBTB41	0.825664184	1.29E-31
UCS	TF	DHX29	HIF1A	0.86998633	1.18E-38
UCS	TSG	DHX29	ANXA7	0.805696439	4.58E-29
UCS	TSG	DHX29	PTPN1	0.819178671	9.42E-31
UCS	TSG	DHX29	CSNK1A1	0.828584663	5.14E-32
UCS	TSG	DHX29	HIF1A	0.86998633	1.18E-38
UVM	Cell metabolism gene	DHX29	MTR	0.800839734	4.79E-19
UVM	Cell metabolism gene	DHX29	GNPDA2	0.801444383	4.31E-19
UVM	Cell metabolism gene	DHX29	VAPA	0.801553473	4.23E-19
UVM	Cell metabolism gene	DHX29	PIGA	0.802522611	3.56E-19
UVM	Cell metabolism gene	DHX29	SGPP1	0.803015138	3.26E-19
UVM	Cell metabolism gene	DHX29	SPTLC1	0.80351357	2.99E-19
UVM	Cell metabolism gene	DHX29	SUCLA2	0.803710841	2.88E-19
UVM	Cell metabolism gene	DHX29	HMGCR	0.804033866	2.72E-19
UVM	Cell metabolism gene	DHX29	RFK	0.804465266	2.52E-19
UVM	Cell metabolism gene	DHX29	POLR3G	0.804728617	2.40E-19
UVM	Cell metabolism gene	DHX29	FUT8	0.804769681	2.39E-19
UVM	Cell metabolism gene	DHX29	PPAT	0.805210456	2.20E-19
UVM	Cell metabolism gene	DHX29	XRN2	0.805211321	2.20E-19
UVM	Cell metabolism gene	DHX29	C1GALT1	0.80551746	2.09E-19
UVM	Cell metabolism gene	DHX29	TRMT11	0.805611735	2.05E-19
UVM	Cell metabolism gene	DHX29	ACADM	0.805880498	1.95E-19
UVM	Cell metabolism gene	DHX29	PSME4	0.806089843	1.88E-19
UVM	Cell metabolism gene	DHX29	UGP2	0.807285078	1.51E-19
UVM	Cell metabolism gene	DHX29	UGCG	0.80738645	1.49E-19
UVM	Cell metabolism gene	DHX29	NUPL1	0.807607742	1.43E-19
UVM	Cell metabolism gene	DHX29	DLAT	0.808631218	1.18E-19
UVM	Cell metabolism gene	DHX29	PIK3C2A	0.808632442	1.18E-19
UVM	Cell metabolism gene	DHX29	DIS3	0.809176877	1.07E-19
UVM	Cell metabolism gene	DHX29	PLA2G12A	0.810451075	8.47E-20
UVM	Cell metabolism gene	DHX29	MCEE	0.810552627	8.31E-20
UVM	Cell metabolism gene	DHX29	GCLM	0.810584383	8.26E-20
UVM	Cell metabolism gene	DHX29	PSMD14	0.810725443	8.05E-20
UVM	Cell metabolism gene	DHX29	PSMA4	0.811489239	6.98E-20
UVM	Cell metabolism gene	DHX29	SMG1	0.811552491	6.90E-20
UVM	Cell metabolism gene	DHX29	GPD2	0.811777996	6.62E-20
UVM	Cell metabolism gene	DHX29	CANX	0.811876387	6.49E-20
UVM	Cell metabolism gene	DHX29	HSD17B4	0.812013885	6.33E-20
UVM	Cell metabolism gene	DHX29	DLD	0.812725413	5.54E-20
UVM	Cell metabolism gene	DHX29	LYPLA1	0.813178773	5.09E-20
UVM	Cell metabolism gene	DHX29	MTM1	0.813193226	5.07E-20
UVM	Cell metabolism gene	DHX29	SRP54	0.813751204	4.57E-20
UVM	Cell metabolism gene	DHX29	PIK3R1	0.817366219	2.29E-20
UVM	Cell metabolism gene	DHX29	UPRT	0.819231985	1.59E-20
UVM	Cell metabolism gene	DHX29	GLS	0.819591524	1.48E-20
UVM	Cell metabolism gene	DHX29	NUP107	0.819705796	1.45E-20
UVM	Cell metabolism gene	DHX29	AGPS	0.821314943	1.06E-20
UVM	Cell metabolism gene	DHX29	PPP2CA	0.821598426	9.99E-21
UVM	Cell metabolism gene	DHX29	ALG13	0.821765358	9.66E-21
UVM	Cell metabolism gene	DHX29	FPGT	0.822414782	8.49E-21
UVM	Cell metabolism gene	DHX29	PIK3C3	0.823784862	6.45E-21
UVM	Cell metabolism gene	DHX29	PIKFYVE	0.825099109	4.95E-21
UVM	Cell metabolism gene	DHX29	PI4K2B	0.827959495	2.76E-21
UVM	Cell metabolism gene	DHX29	TXNRD1	0.828431836	2.50E-21
UVM	Cell metabolism gene	DHX29	FBXL3	0.829246126	2.11E-21
UVM	Cell metabolism gene	DHX29	ACSL4	0.832967419	9.63E-22
UVM	Cell metabolism gene	DHX29	DCK	0.833047436	9.47E-22
UVM	Cell metabolism gene	DHX29	AASDHPPT	0.833099278	9.37E-22
UVM	Cell metabolism gene	DHX29	PSMA2	0.834509856	6.92E-22
UVM	Cell metabolism gene	DHX29	SDHD	0.835684958	5.37E-22
UVM	Cell metabolism gene	DHX29	EDEM3	0.83643013	4.56E-22
UVM	Cell metabolism gene	DHX29	CDK8	0.837121689	3.92E-22
UVM	Cell metabolism gene	DHX29	NUP50	0.837327124	3.75E-22
UVM	Cell metabolism gene	DHX29	ETNK1	0.838162086	3.12E-22
UVM	Cell metabolism gene	DHX29	MINPP1	0.839174641	2.49E-22
UVM	Cell metabolism gene	DHX29	DBT	0.840951811	1.67E-22
UVM	Cell metabolism gene	DHX29	MED7	0.842998874	1.05E-22
UVM	Cell metabolism gene	DHX29	IDI1	0.84336568	9.68E-23
UVM	Cell metabolism gene	DHX29	MANEA	0.843859874	8.64E-23
UVM	Cell metabolism gene	DHX29	FAR1	0.845217922	6.31E-23
UVM	Cell metabolism gene	DHX29	XPO1	0.845583518	5.80E-23
UVM	Cell metabolism gene	DHX29	ADK	0.846231216	4.99E-23
UVM	Cell metabolism gene	DHX29	CNOT8	0.84771544	3.52E-23
UVM	Cell metabolism gene	DHX29	GRPEL2	0.849166841	2.49E-23
UVM	Cell metabolism gene	DHX29	SACM1L	0.849307014	2.41E-23
UVM	Cell metabolism gene	DHX29	RANBP2	0.850190001	1.95E-23
UVM	Cell metabolism gene	DHX29	NUDT12	0.853043313	9.76E-24
UVM	Cell metabolism gene	DHX29	CSGALNACT2	0.853198898	9.39E-24
UVM	Cell metabolism gene	DHX29	MED17	0.853707861	8.29E-24
UVM	Cell metabolism gene	DHX29	PANK3	0.854287384	7.18E-24
UVM	Cell metabolism gene	DHX29	VBP1	0.859283201	2.03E-24
UVM	Cell metabolism gene	DHX29	ACADSB	0.859368682	1.99E-24
UVM	Cell metabolism gene	DHX29	MTMR6	0.862664595	8.43E-25
UVM	Cell metabolism gene	DHX29	PRKAA1	0.876238483	1.90E-26
UVM	Cell metabolism gene	DHX29	CLOCK	0.878522596	9.62E-27
UVM	Cell metabolism gene	DHX29	SRP19	0.879498135	7.16E-27
UVM	Cell metabolism gene	DHX29	NUPL2	0.880986155	4.54E-27
UVM	Cell metabolism gene	DHX29	NAMPT	0.886153153	8.90E-28
UVM	Cell metabolism gene	DHX29	UGGT2	0.887887963	5.06E-28
UVM	Cell metabolism gene	DHX29	PSMC6	0.892767958	9.81E-29
UVM	Cell metabolism gene	DHX29	PNPLA8	0.894781775	4.87E-29
UVM	Cell metabolism gene	DHX29	TNPO1	0.895699222	3.53E-29
UVM	Cell metabolism gene	DHX29	COL4A3BP	0.909206688	2.05E-31
UVM	Cell metabolism gene	DHX29	PHAX	0.919881901	1.92E-33
UVM	CGC	DHX29	RABEP1	0.801110484	4.57E-19
UVM	CGC	DHX29	TRIM33	0.801725554	4.10E-19
UVM	CGC	DHX29	GOPC	0.802141363	3.81E-19
UVM	CGC	DHX29	BMPR1A	0.802426256	3.62E-19
UVM	CGC	DHX29	MSH2	0.802685004	3.46E-19
UVM	CGC	DHX29	TRIP11	0.803419013	3.04E-19
UVM	CGC	DHX29	TOP1	0.806018038	1.91E-19
UVM	CGC	DHX29	ARID2	0.808081987	1.31E-19
UVM	CGC	DHX29	ERCC4	0.808622844	1.19E-19
UVM	CGC	DHX29	POT1	0.809621166	9.87E-20
UVM	CGC	DHX29	FBXO11	0.809941724	9.31E-20
UVM	CGC	DHX29	CUL3	0.810805683	7.93E-20
UVM	CGC	DHX29	ATRX	0.811451047	7.03E-20
UVM	CGC	DHX29	RGPD3	0.812382584	5.91E-20
UVM	CGC	DHX29	CLIP1	0.814818532	3.73E-20
UVM	CGC	DHX29	IL6ST	0.815441082	3.31E-20
UVM	CGC	DHX29	FIP1L1	0.816277333	2.82E-20
UVM	CGC	DHX29	PIK3R1	0.817366219	2.29E-20
UVM	CGC	DHX29	AKAP9	0.818458522	1.85E-20
UVM	CGC	DHX29	ZMYM2	0.820754498	1.18E-20
UVM	CGC	DHX29	MALT1	0.820796807	1.17E-20
UVM	CGC	DHX29	ARHGAP5	0.821512812	1.02E-20
UVM	CGC	DHX29	BCLAF1	0.826006244	4.12E-21
UVM	CGC	DHX29	MLLT10	0.826397772	3.80E-21
UVM	CGC	DHX29	ATF1	0.829975019	1.81E-21
UVM	CGC	DHX29	PMS1	0.831474279	1.32E-21
UVM	CGC	DHX29	DDX10	0.835412134	5.69E-22
UVM	CGC	DHX29	SDHD	0.835684958	5.37E-22
UVM	CGC	DHX29	AFF4	0.836015545	4.99E-22
UVM	CGC	DHX29	APC	0.836234215	4.76E-22
UVM	CGC	DHX29	ETNK1	0.838162086	3.12E-22
UVM	CGC	DHX29	ITGAV	0.84482027	6.92E-23
UVM	CGC	DHX29	BAZ1A	0.844982475	6.67E-23
UVM	CGC	DHX29	XPO1	0.845583518	5.80E-23
UVM	CGC	DHX29	ABI1	0.84607601	5.17E-23
UVM	CGC	DHX29	SF3B1	0.846154278	5.08E-23
UVM	CGC	DHX29	DICER1	0.848064155	3.24E-23
UVM	CGC	DHX29	STAG2	0.848353242	3.03E-23
UVM	CGC	DHX29	RANBP2	0.850190001	1.95E-23
UVM	CGC	DHX29	ATM	0.851727132	1.35E-23
UVM	CGC	DHX29	CDC73	0.856237274	4.41E-24
UVM	CGC	DHX29	GOLGA5	0.858019168	2.81E-24
UVM	CGC	DHX29	USP8	0.858975398	2.20E-24
UVM	CGC	DHX29	KTN1	0.864263641	5.51E-25
UVM	CGC	DHX29	DDX5	0.867439125	2.33E-25
UVM	CGC	DHX29	PWWP2A	0.870258079	1.07E-25
UVM	CGC	DHX29	RAD17	0.872274771	6.02E-26
UVM	CGC	DHX29	HSP90AA1	0.875534418	2.34E-26
UVM	CGC	DHX29	SUZ12	0.878256748	1.04E-26
UVM	CGC	DHX29	KIF5B	0.886639256	7.61E-28
UVM	Epifactor	DHX29	ATF2	0.800476917	5.11E-19
UVM	Epifactor	DHX29	CBX3	0.801101708	4.58E-19
UVM	Epifactor	DHX29	TRIM33	0.801725554	4.10E-19
UVM	Epifactor	DHX29	CDK17	0.801732027	4.10E-19
UVM	Epifactor	DHX29	SMARCAD1	0.802106859	3.83E-19
UVM	Epifactor	DHX29	PHF20L1	0.80284609	3.36E-19
UVM	Epifactor	DHX29	ATAD2B	0.805184426	2.21E-19
UVM	Epifactor	DHX29	DR1	0.805970892	1.92E-19
UVM	Epifactor	DHX29	ARID2	0.808081987	1.31E-19
UVM	Epifactor	DHX29	BRWD3	0.808907193	1.13E-19
UVM	Epifactor	DHX29	CUL3	0.810805683	7.93E-20
UVM	Epifactor	DHX29	PHF14	0.811100949	7.51E-20
UVM	Epifactor	DHX29	ATRX	0.811451047	7.03E-20
UVM	Epifactor	DHX29	PHIP	0.81433713	4.09E-20
UVM	Epifactor	DHX29	EPC1	0.814455199	4.00E-20
UVM	Epifactor	DHX29	AEBP2	0.815237065	3.44E-20
UVM	Epifactor	DHX29	ANKRD32	0.8173989	2.27E-20
UVM	Epifactor	DHX29	RLIM	0.818644137	1.79E-20
UVM	Epifactor	DHX29	YY1	0.819978129	1.38E-20
UVM	Epifactor	DHX29	OGT	0.820600548	1.22E-20
UVM	Epifactor	DHX29	ZMYM2	0.820754498	1.18E-20
UVM	Epifactor	DHX29	MASTL	0.820912734	1.14E-20
UVM	Epifactor	DHX29	FAM175B	0.8213699	1.05E-20
UVM	Epifactor	DHX29	PPP2CA	0.821598426	9.99E-21
UVM	Epifactor	DHX29	ARID4A	0.822047225	9.14E-21
UVM	Epifactor	DHX29	WAC	0.822452094	8.43E-21
UVM	Epifactor	DHX29	EPC2	0.824156695	5.99E-21
UVM	Epifactor	DHX29	TDG	0.824254962	5.87E-21
UVM	Epifactor	DHX29	SKP1	0.825357283	4.70E-21
UVM	Epifactor	DHX29	UBE2B	0.825742234	4.34E-21
UVM	Epifactor	DHX29	MLLT10	0.826397772	3.80E-21
UVM	Epifactor	DHX29	CHD9	0.826910199	3.42E-21
UVM	Epifactor	DHX29	SMARCA5	0.82800944	2.73E-21
UVM	Epifactor	DHX29	ACTR6	0.828086868	2.68E-21
UVM	Epifactor	DHX29	ZMYND11	0.828174795	2.64E-21
UVM	Epifactor	DHX29	RMI1	0.829692103	1.92E-21
UVM	Epifactor	DHX29	H2AFV	0.829852562	1.86E-21
UVM	Epifactor	DHX29	HCFC2	0.831399748	1.34E-21
UVM	Epifactor	DHX29	HAT1	0.832406092	1.09E-21
UVM	Epifactor	DHX29	ZRANB3	0.837739046	3.42E-22
UVM	Epifactor	DHX29	TAF9	0.837913518	3.29E-22
UVM	Epifactor	DHX29	BAZ2B	0.839025628	2.58E-22
UVM	Epifactor	DHX29	YEATS4	0.842462695	1.19E-22
UVM	Epifactor	DHX29	BRMS1L	0.84395961	8.44E-23
UVM	Epifactor	DHX29	BAZ1A	0.844982475	6.67E-23
UVM	Epifactor	DHX29	SF3B1	0.846154278	5.08E-23
UVM	Epifactor	DHX29	DNTTIP2	0.849360724	2.38E-23
UVM	Epifactor	DHX29	ATM	0.851727132	1.35E-23
UVM	Epifactor	DHX29	JMJD1C	0.851959779	1.27E-23
UVM	Epifactor	DHX29	CDC73	0.856237274	4.41E-24
UVM	Epifactor	DHX29	NIPBL	0.857539214	3.18E-24
UVM	Epifactor	DHX29	CHD1	0.860313204	1.56E-24
UVM	Epifactor	DHX29	CHUK	0.864100882	5.75E-25
UVM	Epifactor	DHX29	UCHL5	0.865840821	3.60E-25
UVM	Epifactor	DHX29	SMEK2	0.871747375	6.99E-26
UVM	Epifactor	DHX29	USP15	0.873235347	4.57E-26
UVM	Epifactor	DHX29	SMEK1	0.874175061	3.48E-26
UVM	Epifactor	DHX29	PRKAA1	0.876238483	1.90E-26
UVM	Epifactor	DHX29	TLK1	0.876416513	1.80E-26
UVM	Epifactor	DHX29	SUZ12	0.878256748	1.04E-26
UVM	Epifactor	DHX29	TAF7	0.878483973	9.74E-27
UVM	Epifactor	DHX29	CLOCK	0.878522596	9.62E-27
UVM	Epifactor	DHX29	CUL5	0.879560595	7.03E-27
UVM	Epifactor	DHX29	BRCC3	0.880665811	5.01E-27
UVM	Epifactor	DHX29	CUL2	0.896821902	2.36E-29
UVM	IUPHAR	DHX29	MTR	0.800839734	4.79E-19
UVM	IUPHAR	DHX29	TRIM33	0.801725554	4.10E-19
UVM	IUPHAR	DHX29	CDK17	0.801732027	4.10E-19
UVM	IUPHAR	DHX29	PRPF4B	0.801837918	4.02E-19
UVM	IUPHAR	DHX29	BMPR1A	0.802426256	3.62E-19
UVM	IUPHAR	DHX29	CLK4	0.802528235	3.56E-19
UVM	IUPHAR	DHX29	SGPP1	0.803015138	3.26E-19
UVM	IUPHAR	DHX29	SLC26A2	0.803175828	3.17E-19
UVM	IUPHAR	DHX29	MARK3	0.803418384	3.04E-19
UVM	IUPHAR	DHX29	SPTLC1	0.80351357	2.99E-19
UVM	IUPHAR	DHX29	IDE	0.803698501	2.89E-19
UVM	IUPHAR	DHX29	SLC38A2	0.803980901	2.75E-19
UVM	IUPHAR	DHX29	HMGCR	0.804033866	2.72E-19
UVM	IUPHAR	DHX29	SLC25A40	0.804500091	2.50E-19
UVM	IUPHAR	DHX29	ATAD2B	0.805184426	2.21E-19
UVM	IUPHAR	DHX29	PPAT	0.805210456	2.20E-19
UVM	IUPHAR	DHX29	TOP1	0.806018038	1.91E-19
UVM	IUPHAR	DHX29	SLC37A3	0.806331524	1.80E-19
UVM	IUPHAR	DHX29	IFNGR1	0.806557632	1.73E-19
UVM	IUPHAR	DHX29	UGCG	0.80738645	1.49E-19
UVM	IUPHAR	DHX29	SLC25A24	0.807561461	1.44E-19
UVM	IUPHAR	DHX29	STK38L	0.808256515	1.27E-19
UVM	IUPHAR	DHX29	PIK3C2A	0.808632442	1.18E-19
UVM	IUPHAR	DHX29	BRWD3	0.808907193	1.13E-19
UVM	IUPHAR	DHX29	FBXO11	0.809941724	9.31E-20
UVM	IUPHAR	DHX29	PLA2G12A	0.810451075	8.47E-20
UVM	IUPHAR	DHX29	SLC30A9	0.810704262	8.08E-20
UVM	IUPHAR	DHX29	PSMD14	0.810725443	8.05E-20
UVM	IUPHAR	DHX29	EGLN1	0.810760377	8.00E-20
UVM	IUPHAR	DHX29	SMG1	0.811552491	6.90E-20
UVM	IUPHAR	DHX29	TMEM165	0.811785604	6.61E-20
UVM	IUPHAR	DHX29	NR2C1	0.812483517	5.80E-20
UVM	IUPHAR	DHX29	PHIP	0.81433713	4.09E-20
UVM	IUPHAR	DHX29	IL6ST	0.815441082	3.31E-20
UVM	IUPHAR	DHX29	ADAM17	0.81615464	2.89E-20
UVM	IUPHAR	DHX29	MAGT1	0.816937269	2.48E-20
UVM	IUPHAR	DHX29	NIPA1	0.816950973	2.48E-20
UVM	IUPHAR	DHX29	PIK3R1	0.817366219	2.29E-20
UVM	IUPHAR	DHX29	SLC30A7	0.817466802	2.24E-20
UVM	IUPHAR	DHX29	ABCA5	0.817611172	2.18E-20
UVM	IUPHAR	DHX29	USP1	0.818374942	1.88E-20
UVM	IUPHAR	DHX29	GLS	0.819591524	1.48E-20
UVM	IUPHAR	DHX29	MALT1	0.820796807	1.17E-20
UVM	IUPHAR	DHX29	MASTL	0.820912734	1.14E-20
UVM	IUPHAR	DHX29	MAP4K3	0.823114399	7.38E-21
UVM	IUPHAR	DHX29	PIK3C3	0.823784862	6.45E-21
UVM	IUPHAR	DHX29	PIKFYVE	0.825099109	4.95E-21
UVM	IUPHAR	DHX29	TAOK3	0.825242618	4.81E-21
UVM	IUPHAR	DHX29	RIOK3	0.825591568	4.48E-21
UVM	IUPHAR	DHX29	PI4K2B	0.827959495	2.76E-21
UVM	IUPHAR	DHX29	ZMYND11	0.828174795	2.64E-21
UVM	IUPHAR	DHX29	TRPM7	0.830660297	1.57E-21
UVM	IUPHAR	DHX29	NEK7	0.831085408	1.44E-21
UVM	IUPHAR	DHX29	HAT1	0.832406092	1.09E-21
UVM	IUPHAR	DHX29	SCYL2	0.835762726	5.28E-22
UVM	IUPHAR	DHX29	CDK8	0.837121689	3.92E-22
UVM	IUPHAR	DHX29	BAZ2B	0.839025628	2.58E-22
UVM	IUPHAR	DHX29	NEK1	0.839599334	2.27E-22
UVM	IUPHAR	DHX29	PRMT3	0.839778678	2.18E-22
UVM	IUPHAR	DHX29	TNKS2	0.84236524	1.22E-22
UVM	IUPHAR	DHX29	PKN2	0.84310167	1.03E-22
UVM	IUPHAR	DHX29	IDI1	0.84336568	9.68E-23
UVM	IUPHAR	DHX29	ITGAV	0.84482027	6.92E-23
UVM	IUPHAR	DHX29	BAZ1A	0.844982475	6.67E-23
UVM	IUPHAR	DHX29	XPO1	0.845583518	5.80E-23
UVM	IUPHAR	DHX29	ADK	0.846231216	4.99E-23
UVM	IUPHAR	DHX29	VRK2	0.848170056	3.16E-23
UVM	IUPHAR	DHX29	SLK	0.850088953	2.00E-23
UVM	IUPHAR	DHX29	MAPK6	0.85031142	1.90E-23
UVM	IUPHAR	DHX29	ATM	0.851727132	1.35E-23
UVM	IUPHAR	DHX29	JMJD1C	0.851959779	1.27E-23
UVM	IUPHAR	DHX29	IRAK4	0.853575144	8.56E-24
UVM	IUPHAR	DHX29	BIRC2	0.862724593	8.29E-25
UVM	IUPHAR	DHX29	CHUK	0.864100882	5.75E-25
UVM	IUPHAR	DHX29	STK17A	0.869836822	1.20E-25
UVM	IUPHAR	DHX29	RIOK2	0.870143867	1.10E-25
UVM	IUPHAR	DHX29	TBK1	0.873395314	4.36E-26
UVM	IUPHAR	DHX29	XIAP	0.874130857	3.53E-26
UVM	IUPHAR	DHX29	HSP90AA1	0.875534418	2.34E-26
UVM	IUPHAR	DHX29	PRKAA1	0.876238483	1.90E-26
UVM	IUPHAR	DHX29	TLK1	0.876416513	1.80E-26
UVM	IUPHAR	DHX29	CLOCK	0.878522596	9.62E-27
UVM	IUPHAR	DHX29	SLC25A46	0.883241022	2.25E-27
UVM	IUPHAR	DHX29	MAP3K2	0.883596105	2.01E-27
UVM	IUPHAR	DHX29	USP14	0.888217171	4.54E-28
UVM	IUPHAR	DHX29	SLC30A5	0.897330469	1.97E-29
UVM	IUPHAR	DHX29	CSNK1G3	0.900317218	6.60E-30
UVM	IUPHAR	DHX29	CSNK1A1	0.903705373	1.83E-30
UVM	Kinase	DHX29	TRIM33	0.801725554	4.10E-19
UVM	Kinase	DHX29	CDK17	0.801732027	4.10E-19
UVM	Kinase	DHX29	PRPF4B	0.801837918	4.02E-19
UVM	Kinase	DHX29	BMPR1A	0.802426256	3.62E-19
UVM	Kinase	DHX29	CLK4	0.802528235	3.56E-19
UVM	Kinase	DHX29	MARK3	0.803418384	3.04E-19
UVM	Kinase	DHX29	STK38L	0.808256515	1.27E-19
UVM	Kinase	DHX29	SMG1	0.811552491	6.90E-20
UVM	Kinase	DHX29	MASTL	0.820912734	1.14E-20
UVM	Kinase	DHX29	MAP4K3	0.823114399	7.38E-21
UVM	Kinase	DHX29	TAOK3	0.825242618	4.81E-21
UVM	Kinase	DHX29	RIOK3	0.825591568	4.48E-21
UVM	Kinase	DHX29	TRPM7	0.830660297	1.57E-21
UVM	Kinase	DHX29	NEK7	0.831085408	1.44E-21
UVM	Kinase	DHX29	SCYL2	0.835762726	5.28E-22
UVM	Kinase	DHX29	CDK8	0.837121689	3.92E-22
UVM	Kinase	DHX29	NEK1	0.839599334	2.27E-22
UVM	Kinase	DHX29	PKN2	0.84310167	1.03E-22
UVM	Kinase	DHX29	BAZ1A	0.844982475	6.67E-23
UVM	Kinase	DHX29	VRK2	0.848170056	3.16E-23
UVM	Kinase	DHX29	SLK	0.850088953	2.00E-23
UVM	Kinase	DHX29	MAPK6	0.85031142	1.90E-23
UVM	Kinase	DHX29	ATM	0.851727132	1.35E-23
UVM	Kinase	DHX29	IRAK4	0.853575144	8.56E-24
UVM	Kinase	DHX29	CHUK	0.864100882	5.75E-25
UVM	Kinase	DHX29	STK17A	0.869836822	1.20E-25
UVM	Kinase	DHX29	RIOK2	0.870143867	1.10E-25
UVM	Kinase	DHX29	TBK1	0.873395314	4.36E-26
UVM	Kinase	DHX29	PRKAA1	0.876238483	1.90E-26
UVM	Kinase	DHX29	TLK1	0.876416513	1.80E-26
UVM	Kinase	DHX29	MAP3K2	0.883596105	2.01E-27
UVM	Kinase	DHX29	CSNK1G3	0.900317218	6.60E-30
UVM	Kinase	DHX29	CSNK1A1	0.903705373	1.83E-30
UVM	Kinase	DHX29	COL4A3BP	0.909206688	2.05E-31
UVM	TF	DHX29	ZNF567	0.800183334	5.37E-19
UVM	TF	DHX29	THAP1	0.800446086	5.13E-19
UVM	TF	DHX29	ATF2	0.800476917	5.11E-19
UVM	TF	DHX29	ZBTB41	0.800553395	5.04E-19
UVM	TF	DHX29	ZNF44	0.800645966	4.96E-19
UVM	TF	DHX29	ZNF658	0.800993008	4.66E-19
UVM	TF	DHX29	ELF1	0.801316236	4.41E-19
UVM	TF	DHX29	RLF	0.80160974	4.18E-19
UVM	TF	DHX29	ZNF268	0.801610779	4.18E-19
UVM	TF	DHX29	ZNF546	0.802291107	3.71E-19
UVM	TF	DHX29	ZNF555	0.802447407	3.61E-19
UVM	TF	DHX29	ZBED5	0.803454434	3.02E-19
UVM	TF	DHX29	ZNF138	0.804911483	2.33E-19
UVM	TF	DHX29	ZNF420	0.805191961	2.21E-19
UVM	TF	DHX29	ZNF140	0.805351227	2.15E-19
UVM	TF	DHX29	ZNF280C	0.805851298	1.96E-19
UVM	TF	DHX29	DR1	0.805970892	1.92E-19
UVM	TF	DHX29	ZNF674	0.806563422	1.73E-19
UVM	TF	DHX29	ZNF675	0.80709102	1.57E-19
UVM	TF	DHX29	ZNF182	0.807555019	1.44E-19
UVM	TF	DHX29	ARID2	0.808081987	1.31E-19
UVM	TF	DHX29	ZNF45	0.808239489	1.27E-19
UVM	TF	DHX29	ZNF146	0.81041162	8.53E-20
UVM	TF	DHX29	LIN54	0.810801067	7.94E-20
UVM	TF	DHX29	NFXL1	0.810835715	7.88E-20
UVM	TF	DHX29	ZNF226	0.812057353	6.28E-20
UVM	TF	DHX29	NR2C1	0.812483517	5.80E-20
UVM	TF	DHX29	HDX	0.812680293	5.59E-20
UVM	TF	DHX29	ZNF451	0.81312521	5.14E-20
UVM	TF	DHX29	DMTF1	0.813979479	4.37E-20
UVM	TF	DHX29	ZNF600	0.814604602	3.88E-20
UVM	TF	DHX29	AEBP2	0.815237065	3.44E-20
UVM	TF	DHX29	BACH1	0.815353497	3.37E-20
UVM	TF	DHX29	ZNF254	0.816256301	2.83E-20
UVM	TF	DHX29	ZBTB25	0.816668281	2.62E-20
UVM	TF	DHX29	GABPA	0.816983286	2.46E-20
UVM	TF	DHX29	TERF1	0.818042989	2.01E-20
UVM	TF	DHX29	ELF2	0.819076632	1.64E-20
UVM	TF	DHX29	ZNF440	0.819525656	1.50E-20
UVM	TF	DHX29	TOPORS	0.819904598	1.40E-20
UVM	TF	DHX29	YY1	0.819978129	1.38E-20
UVM	TF	DHX29	ZNF26	0.820648211	1.21E-20
UVM	TF	DHX29	CREBZF	0.820648399	1.21E-20
UVM	TF	DHX29	ZNF280D	0.821405441	1.04E-20
UVM	TF	DHX29	ZNF195	0.822459558	8.42E-21
UVM	TF	DHX29	ZNF101	0.823379078	7.00E-21
UVM	TF	DHX29	ZNF234	0.823643325	6.64E-21
UVM	TF	DHX29	ZNF43	0.824895101	5.16E-21
UVM	TF	DHX29	ZNF700	0.825353556	4.70E-21
UVM	TF	DHX29	RBAK	0.826109395	4.03E-21
UVM	TF	DHX29	PRDM10	0.826553354	3.68E-21
UVM	TF	DHX29	ZNF432	0.827836048	2.83E-21
UVM	TF	DHX29	ZNF510	0.827890623	2.80E-21
UVM	TF	DHX29	MEF2A	0.828412367	2.51E-21
UVM	TF	DHX29	ZNF761	0.828963831	2.24E-21
UVM	TF	DHX29	ZNF75D	0.829489765	2.01E-21
UVM	TF	DHX29	ZNF431	0.829726585	1.91E-21
UVM	TF	DHX29	ATF1	0.829975019	1.81E-21
UVM	TF	DHX29	ZNF25	0.830802206	1.52E-21
UVM	TF	DHX29	ZNF845	0.832293714	1.11E-21
UVM	TF	DHX29	THAP9	0.8326333	1.03E-21
UVM	TF	DHX29	ZNF41	0.833280365	9.01E-22
UVM	TF	DHX29	ZNF468	0.833846685	7.98E-22
UVM	TF	DHX29	ZNF527	0.837853774	3.34E-22
UVM	TF	DHX29	BAZ2B	0.839025628	2.58E-22
UVM	TF	DHX29	ZNF780A	0.839214853	2.47E-22
UVM	TF	DHX29	PRMT3	0.839778678	2.18E-22
UVM	TF	DHX29	ZNF383	0.840199077	1.98E-22
UVM	TF	DHX29	ZNF701	0.841290878	1.55E-22
UVM	TF	DHX29	AHCTF1	0.843755499	8.85E-23
UVM	TF	DHX29	ZNF791	0.844237019	7.92E-23
UVM	TF	DHX29	ZNF180	0.845003448	6.64E-23
UVM	TF	DHX29	ZNF181	0.846761731	4.41E-23
UVM	TF	DHX29	ZNF441	0.847200298	3.97E-23
UVM	TF	DHX29	ZNF33A	0.849248676	2.45E-23
UVM	TF	DHX29	ZNF326	0.851992715	1.26E-23
UVM	TF	DHX29	IKZF5	0.85374743	8.21E-24
UVM	TF	DHX29	ZNF800	0.857741644	3.02E-24
UVM	TF	DHX29	ZNF267	0.85831144	2.61E-24
UVM	TF	DHX29	ZNF484	0.859725352	1.82E-24
UVM	TF	DHX29	ZNF430	0.862867317	7.99E-25
UVM	TF	DHX29	ZNF136	0.865166321	4.32E-25
UVM	TF	DHX29	CEBPZ	0.865637016	3.81E-25
UVM	TF	DHX29	THAP5	0.867218755	2.47E-25
UVM	TF	DHX29	SP3	0.867812727	2.10E-25
UVM	TF	DHX29	ZNF131	0.868011265	1.99E-25
UVM	TF	DHX29	ZNF28	0.869305279	1.39E-25
UVM	TF	DHX29	ZBTB1	0.871640593	7.21E-26
UVM	TF	DHX29	THAP6	0.875811402	2.16E-26
UVM	TF	DHX29	CLOCK	0.878522596	9.62E-27
UVM	TF	DHX29	SMAD5	0.888939641	3.58E-28
UVM	TF	DHX29	GPBP1	0.908015773	3.33E-31
UVM	TSG	DHX29	BMPR1A	0.802426256	3.62E-19
UVM	TSG	DHX29	MSH2	0.802685004	3.46E-19
UVM	TSG	DHX29	ARID2	0.808081987	1.31E-19
UVM	TSG	DHX29	SH3GLB1	0.809074432	1.09E-19
UVM	TSG	DHX29	USP33	0.810432293	8.50E-20
UVM	TSG	DHX29	EGLN1	0.810760377	8.00E-20
UVM	TSG	DHX29	DMTF1	0.813979479	4.37E-20
UVM	TSG	DHX29	TOPORS	0.819904598	1.40E-20
UVM	TSG	DHX29	PPP2CA	0.821598426	9.99E-21
UVM	TSG	DHX29	VEZT	0.82433098	5.78E-21
UVM	TSG	DHX29	ZMYND11	0.828174795	2.64E-21
UVM	TSG	DHX29	COPS2	0.830491032	1.63E-21
UVM	TSG	DHX29	RINT1	0.83079684	1.53E-21
UVM	TSG	DHX29	ANXA7	0.834856165	6.42E-22
UVM	TSG	DHX29	SDHD	0.835684958	5.37E-22
UVM	TSG	DHX29	APC	0.836234215	4.76E-22
UVM	TSG	DHX29	NEDD4	0.83642499	4.57E-22
UVM	TSG	DHX29	DCLRE1A	0.843182466	1.01E-22
UVM	TSG	DHX29	MLH3	0.844679442	7.15E-23
UVM	TSG	DHX29	ITGAV	0.84482027	6.92E-23
UVM	TSG	DHX29	GGNBP2	0.845939204	5.34E-23
UVM	TSG	DHX29	DICER1	0.848064155	3.24E-23
UVM	TSG	DHX29	SMCHD1	0.848194921	3.14E-23
UVM	TSG	DHX29	RB1CC1	0.849451712	2.33E-23
UVM	TSG	DHX29	TANK	0.850443714	1.84E-23
UVM	TSG	DHX29	ATM	0.851727132	1.35E-23
UVM	TSG	DHX29	CDC73	0.856237274	4.41E-24
UVM	TSG	DHX29	CCAR1	0.858822967	2.29E-24
UVM	TSG	DHX29	CHD1	0.860313204	1.56E-24
UVM	TSG	DHX29	CHUK	0.864100882	5.75E-25
UVM	TSG	DHX29	WDR11	0.866079066	3.38E-25
UVM	TSG	DHX29	KRIT1	0.86815763	1.91E-25
UVM	TSG	DHX29	GORAB	0.86974057	1.23E-25
UVM	TSG	DHX29	INTS6	0.873994627	3.67E-26
UVM	TSG	DHX29	FAM188A	0.874444614	3.22E-26
UVM	TSG	DHX29	PRKAA1	0.876238483	1.90E-26
UVM	TSG	DHX29	SUZ12	0.878256748	1.04E-26
UVM	TSG	DHX29	CUL5	0.879560595	7.03E-27
UVM	TSG	DHX29	RBBP8	0.882687218	2.68E-27
UVM	TSG	DHX29	PPM1A	0.891289741	1.63E-28
UVM	TSG	DHX29	CUL2	0.896821902	2.36E-29
UVM	TSG	DHX29	CSNK1A1	0.903705373	1.83E-30

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
HNSC	DHX29	EIF1	-4.13399438210909	0.000228392819053625
STAD	DHX29	RPS23	1.85076760664576	0.000364991836249828
KIRP	DHX29	RPS14	-1.10710481020121	0.00114433001726866
LUAD	DHX29	EIF3J	-1.1109238877878	0.00216965225011196
LIHC	DHX29	EIF5B	-2.20229681831546	0.00440340335695336
PRAD	DHX29	EIF1	1.32822648991353	0.00674237731133815
COAD	DHX29	EIF5B	-1.84319839410667	0.0101850330829621
LUSC	DHX29	RPS23	1.46751169891047	0.0174932185880974
COAD	DHX29	RPS9	1.18612014402235	0.0381683111190796
UCEC	DHX29	RPS23	-2.03658159814007	0.046875
THCA	DHX29	RPS14	1.18855682463527	0.0484049760061147
HNSC	DHX29	RPS25	2.24439018636525	1.07420805761649e-06
THCA	DHX29	EIF3J	1.32428508175103	1.19078203681914e-07
THCA	DHX29	RPS2	-2.9749691422722	1.8399565126656e-05
KIRC	DHX29	RPS2	-3.31623058345719	2.17100738110179e-12
BRCA	DHX29	RPS9	1.9331477546349	2.31299392089389e-07
BRCA	DHX29	EIF4B	-2.16032742029696	2.35556737304054e-22
KICH	DHX29	EIF3J	2.09716749126717	3.19480895996094e-05
KIRP	DHX29	RPS2	-2.72788021566791	5.12227416038514e-08
LUAD	DHX29	RPS2	-2.88992098496468	6.51132046672323e-08
KIRC	DHX29	RPS9	-1.32680816440987	6.53264115309597e-07
KIRC	DHX29	EIF4B	1.14997140510474	7.59366366705366e-09
BRCA	DHX29	EIF5B	2.09894664144155	8.11370754946327e-13
KICH	DHX29	RPS2	-4.73426315307469	8.34465026855468e-07
KIRP	DHX29	EIF1AX	1.69033449545845	9.99853946268559e-05

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with DHX29

CENPT, PISD, COPS5, PAPOLG, FOXM1, RECQL5, CHUK, IFIT2, NAPA, HAUS7, POGLUT1, MTHFD2, NTRK1, CKAP5, DNAJC17, EDF1, IFI16, HNRNPU, NPM1, RPL10, C1qbp, Eif3a, Rpl35, Rrbp1, Setd2, POU5F1, CDH1, CDX1, vIRF-4, LARP7, MYC, CSK, GBF1, APEX1, MAB21L2, VAMP5, SNRNP70, PTPN6, BIRC3, NFX1, WWP2, TRIM28, OBSL1, PLEKHA4, OPTN, SOCS1, RPS9, N, nsp2, ESR1, STAU1, CAPRIN1, PRC1, LRRC59, nsp7, EIF3H, DNAJC2, DCTN1, FBL, UBQLN1, FZR1, NAA40, PABPC5, RPL7L1, FTL, RBMS2, SLFN11, SIRT6,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
DHX29	chr5	54586078	T	A	single_nucleotide_variant	Uncertain_significance	Malignant_tumor_of_prostate	SO:0001583\|missense_variant,SO:0001619\|non-coding_transcript_variant,SO:0001623\|5_prime_UTR_variant	SO:0001583\|missense_variant,SO:0001619\|non-coding_transcript_variant,SO:0001623\|5_prime_UTR_variant
DHX29	chr5	54591229	T	C	single_nucleotide_variant	not_provided	not_provided	SO:0001583\|missense_variant,SO:0001619\|non-coding_transcript_variant,SO:0001623\|5_prime_UTR_variant	SO:0001583\|missense_variant,SO:0001619\|non-coding_transcript_variant,SO:0001623\|5_prime_UTR_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
DHX29	LUAD	chr5	54572988	54572988	T	C	Silent	p.T744T	7
DHX29	LIHC	chr5	54570511	54570511	A	-	Frame_Shift_Del	p.L874fs	5
DHX29	LIHC	chr5	54586096	54586096	T	-	Frame_Shift_Del	p.N286fs	5
DHX29	ESCA	chr5	54589922	54589922	G	A	Nonsense_Mutation	p.R235*	4
DHX29	SKCM	chr5	54577320	54577320	G	A	Silent	p.I663I	3
DHX29	UCEC	chr5	54579080	54579080	G	A	Missense_Mutation	p.A639V	3
DHX29	UCEC	chr5	54565263	54565263	A	T	Missense_Mutation	p.I1091K	3
DHX29	LIHC	chr5	54581553	54581553	T	-	Frame_Shift_Del	p.K401fs	3
DHX29	UCEC	chr5	54572230	54572230	A	T	Missense_Mutation	p.F764Y	3
DHX29	BRCA	chr5	54565406	54565406	G	A	Silent	p.L1043	3
DHX29	BLCA	chr5	54566508	54566508	G	T	Missense_Mutation	p.S964Y	3
DHX29	UCEC	chr5	54558480	54558480	C	A	Missense_Mutation	p.G1269V	3
DHX29	LIHC	chr5	54552330	54552330	T	-	Frame_Shift_Del	p.T1366fs	3
DHX29	UCEC	chr5	54579264	54579264	G	A	Missense_Mutation	p.R578W	3
DHX29	READ	chr5	54570457	54570457	C	A	Missense_Mutation	p.R892I	3
DHX29	SKCM	chr5	54570741	54570741	G	A	Missense_Mutation	p.P842L	3
DHX29	LIHC	chr5	54557291	54557291	G	-	Frame_Shift_Del	p.L1289fs	2
DHX29	SARC	chr5	54586147	54586147	G	A	Missense_Mutation		2
DHX29	BLCA	chr5	54585110	54585110	C	T	Missense_Mutation	p.E352K	2
DHX29	STAD	chr5	54569171	54569171	T	C	Missense_Mutation	p.T909A	2
DHX29	UCEC	chr5	54566428	54566428	A	G	Missense_Mutation	p.F991L	2
DHX29	LIHC	chr5	54570765	54570765	T	C	Missense_Mutation		2
DHX29	LUAD	chr5	54563598	54563598	C	A	Missense_Mutation	p.G1116V	2
DHX29	LIHC	chr5	54565332	54565332	G	-	Frame_Shift_Del	p.P1068fs	2
DHX29	SKCM	chr5	54569141	54569141	G	T	Missense_Mutation	p.P919T	2
DHX29	UCEC	chr5	54572987	54572987	A	G	Missense_Mutation	p.Y745H	2
DHX29	STAD	chr5	54581162	54581162	G	T	Missense_Mutation		2
DHX29	BLCA	chr5	54581607	54581607	C	G	Silent	p.L383L	2
DHX29	SKCM	chr5	54581585	54581585	G	A	Missense_Mutation	p.L391F	2
DHX29	KIRC	chr5	54585151	54585151	G	A	Missense_Mutation	p.A338V	2
DHX29	SKCM	chr5	54565332	54565332	G	A	Missense_Mutation	p.P1068L	2
DHX29	BLCA	chr5	54579357	54579357	C	T	Missense_Mutation	p.E547K	2
DHX29	STAD	chr5	54579256	54579256	T	C	Silent	p.S580S	2
DHX29	UCEC	chr5	54579354	54579354	G	A	Missense_Mutation	p.P548S	2
DHX29	STAD	chr5	54581549	54581549	G	A	Missense_Mutation		2
DHX29	SKCM	chr5	54579183	54579183	C	T	Missense_Mutation	p.V605I	2
DHX29	BLCA	chr5	54579455	54579455	C	G	Missense_Mutation	p.R514T	2
DHX29	STAD	chr5	54552344	54552344	G	A	Missense_Mutation	p.T1361M	2
DHX29	UCEC	chr5	54579512	54579512	A	C	Missense_Mutation	p.L495R	2
DHX29	SARC	chr5	54593193	54593193	T	A	Missense_Mutation		2
DHX29	SKCM	chr5	54593125	54593125	G	A	Silent	p.A121A	2
DHX29	BLCA	chr5	54573026	54573026	G	T	Missense_Mutation	p.L732I	2
DHX29	STAD	chr5	54581162	54581162	G	T	Missense_Mutation	p.L439M	2
DHX29	UCEC	chr5	54581589	54581589	C	A	Missense_Mutation	p.K389N	2
DHX29	SARC	chr5	54593194	54593194	A	T	Silent		2
DHX29	SKCM	chr5	54593126	54593126	G	A	Missense_Mutation	p.A121V	2
DHX29	HNSC	chr5	54585191	54585191	C	T	Missense_Mutation	p.E325K	2
DHX29	LIHC	chr5	54565369	54565369	T	-	Frame_Shift_Del	p.I1056fs	2
DHX29	KIRP	chr5	54591351	54591351	A	G	Silent	p.D169D	2
DHX29	LIHC	chr5	54591239	54591239	T	-	Frame_Shift_Del	p.T207fs	2
DHX29	PRAD	chr5	54558526	54558526	C	T	Missense_Mutation	p.A1254T	2
DHX29	BLCA	chr5	54586091	54586091	G	C	Missense_Mutation	p.Q288E	2
DHX29	STAD	chr5	54581549	54581549	G	A	Missense_Mutation	p.P403S	2
DHX29	UCEC	chr5	54592117	54592117	T	C	Missense_Mutation	p.T146A	2
DHX29	LGG	chr5	54577281	54577281	G	C	Silent		2
DHX29	SKCM	chr5	54552319	54552319	G	A	Silent	p.N1369N	2
DHX29	HNSC	chr5	54569133	54569133	T	A	Silent	p.P921P	2
DHX29	LIHC	chr5	54570765	54570765	T	C	Missense_Mutation	p.Q834R	2
DHX29	KIRP	chr5	54591351	54591351	A	G	Splice_Site	p.D169_splice	2
DHX29	LIHC	chr5	54591291	54591291	T	-	Frame_Shift_Del	p.K189fs	2
DHX29	UCEC	chr5	54557205	54557205	G	C	Missense_Mutation	p.I1317M	2
DHX29	HNSC	chr5	54591224	54591224	C	G	Missense_Mutation	p.E212Q	2
DHX29	LIHC	chr5	54603391	54603391	T	-	Frame_Shift_Del	p.K4fs	2
DHX29	ESCA	chr5	54567972	54567972	C	T	Missense_Mutation	p.G936D	2
DHX29	STAD	chr5	54603263	54603263	T	C	Missense_Mutation	p.T47A	2
DHX29	UCEC	chr5	54557225	54557225	G	T	Missense_Mutation	p.L1311I	2
DHX29	LIHC	chr5	54586093	54586096	TTGT	-	Frame_Shift_Del	p.NK286fs	2
DHX29	SARC	chr5	54586147	54586147	G	A	Missense_Mutation	p.A269V	2
DHX29	CESC	chr5	54591326	54591326	C	T	Missense_Mutation		2
DHX29	SKCM	chr5	54557288	54557288	T	C	Missense_Mutation	p.I1290V	2
DHX29	HNSC	chr5	54603304	54603304	G	A	Missense_Mutation	p.A33V	2
DHX29	LGG	chr5	54577281	54577281	G	C	Silent	p.L676L	2
DHX29	STAD	chr5	54589966	54589966	T	-	Frame_Shift_Del	p.K220fs	2
DHX29	UCEC	chr5	54557230	54557230	C	T	Missense_Mutation	p.R1309H	2
DHX29	CESC	chr5	54567958	54567958	C	T	Missense_Mutation		2
DHX29	UCS	chr5	54570837	54570837	T	C	Splice_Site	p.E810_splice	2
DHX29	LUAD	chr5	54567931	54567931	T	A	Nonsense_Mutation	p.R950*	2
DHX29	SARC	chr5	54593193	54593193	T	A	Missense_Mutation	p.I99F	2
DHX29	HNSC	chr5	54565331	54565331	C	T	Silent	p.P1068P	2
DHX29	SKCM	chr5	54557275	54557275	G	A	Missense_Mutation	p.P1294L	2
DHX29	STAD	chr5	54586064	54586064	T	-	Frame_Shift_Del	p.I297fs	2
DHX29	UCEC	chr5	54557246	54557248	CTT	-	In_Frame_Del	p.E1303in_frame_del	2
DHX29	CESC	chr5	54570469	54570469	G	C	Nonsense_Mutation	p.S888*	2
DHX29	LIHC	chr5	54555705	54555705	T	-	Frame_Shift_Del	p.K1343fs	2
DHX29	BLCA	chr5	54567922	54567922	C	G	Missense_Mutation	p.E953Q	2
DHX29	STAD	chr5	54572100	54572100	T	-	Frame_Shift_Del	p.Y808fs	2
DHX29	UCEC	chr5	54565317	54565317	A	C	Missense_Mutation	p.L1073R	2
DHX29	LIHC	chr5	54563641	54563641	C	T	Missense_Mutation		2
DHX29	SKCM	chr5	54566472	54566472	A	G	Missense_Mutation	p.L976S	2
DHX29	KIRC	chr5	54579213	54579213	C	T	Missense_Mutation	p.G595S	1
DHX29	OV	chr5	54614992	54614992	C	G	Missense_Mutation	p.R587S	1
DHX29	BLCA	chr5	54593119	54593119	T	-	Frame_Shift_Del		1
DHX29	COAD	chr5	54581631	54581631	A	C	Silent	p.T375T	1
DHX29	LGG	chr5	54577289	54577289	T	C	Missense_Mutation	p.R674G	1
DHX29	LIHC	chr5	54591233	54591233	T	-	Frame_Shift_Del	p.T209fs	1
DHX29	SKCM	chr5	54577307	54577307	G	A	Nonsense_Mutation	p.R668*	1
DHX29	ESCA	chr5	54589922	54589922	G	A	Nonsense_Mutation	p.R235X	1
DHX29	SKCM	chr5	54577307	54577307	G	A	Nonsense_Mutation	p.R668X	1
DHX29	BLCA	chr5	54573026	54573026	G	T	Missense_Mutation		1
DHX29	CESC	chr5	54585104	54585104	C	A	Nonsense_Mutation		1
DHX29	TGCT	chr5	54581236	54581236	A	G	Missense_Mutation		1
DHX29	HNSC	chr5	54603249	54603249	G	C	Silent		1
DHX29	KIRC	chr5	54563649	54563649	G	T	Missense_Mutation	p.A1099E	1
DHX29	OV	chr5	54617000	54617000	C	T	Missense_Mutation	p.V412I	1
DHX29	BLCA	chr5	54581186	54581186	C	A	Nonsense_Mutation	p.E431*	1
DHX29	COAD	chr5	54589863	54589867	CTCTT	-	Frame_Shift_Del	p.253_255del	1
DHX29	UCEC	chr5	54558540	54558540	G	A	Missense_Mutation	p.T1249M	1
DHX29	STAD	chr5	54573111	54573111	C	G	Splice_Site	.	1
DHX29	LGG	chr5	54586064	54586064	T	C	Missense_Mutation	p.I297V	1
DHX29	LIHC	chr5	54555714	54555714	A	-	Frame_Shift_Del	p.L1340fs	1
DHX29	SARC	chr5	54558633	54558633	G	T	Missense_Mutation		1
DHX29	ESCA	chr5	54557317	54557317	G	A	Missense_Mutation	p.A1280V	1
DHX29	LUAD	chr5	54581635	54581635	C	A	Missense_Mutation	p.W374L	1
DHX29	BLCA	chr5	54586091	54586091	G	C	Missense_Mutation		1
DHX29	CESC	chr5	54586103	54586103	C	C	Missense_Mutation		1
DHX29	TGCT	chr5	54581236	54581236	A	G	Missense_Mutation	p.V414A	1
DHX29	HNSC	chr5	54565331	54565331	C	T	Silent		1
DHX29	LIHC	chr5	54586093	54586096	TTGT	-	Frame_Shift_Del		1
DHX29	OV	chr5	54581181	54581181	A	G	Silent	p.D432	1
DHX29	COAD	chr5	54593113	54593113	C	T	Silent	p.Q125Q	1
DHX29	LGG	chr5	54573002	54573002	C	T	Missense_Mutation	p.E740K	1
DHX29	LIHC	chr5	54572110	54572110	C	-	Frame_Shift_Del	p.G804fs	1
DHX29	SARC	chr5	54558645	54558645	G	A	Missense_Mutation		1
DHX29	BLCA	chr5	54593189	54593189	C	G	Missense_Mutation	p.G100A	1
DHX29	GBM	chr5	54593198	54593198	C	A	Missense_Mutation		1
DHX29	LUAD	chr5	54581634	54581634	C	A	Missense_Mutation	p.W374C	1
DHX29	BLCA	chr5	54563624	54563624	C	A	Missense_Mutation		1
DHX29	CESC	chr5	54581210	54581210	C	T	Missense_Mutation		1
DHX29	THCA	chr5	54569206	54569207	-	-	Splice_Site		1
DHX29	HNSC	chr5	54557237	54557237	G	T	Silent		1
DHX29	LIHC	chr5	54581616	54581616	T	C	Silent	p.K380K	1
DHX29	KIRC	chr5	54579538	54579538	T	C	Silent	p.K486K	1
DHX29	PRAD	chr5	54557260	54557260	C	A	Missense_Mutation	p.G1299V	1
DHX29	SKCM	chr5	54579186	54579186	G	A	Nonsense_Mutation	p.Q604*	1
DHX29	COAD	chr5	54593119	54593119	T	-	Frame_Shift_Del	p.L124fs	1
DHX29	LGG	chr5	54579475	54579475	T	C	Silent	p.Q507Q	1
DHX29	LIHC	chr5	54572993	54572993	A	-	Frame_Shift_Del	p.S743fs	1
DHX29	BLCA	chr5	54555737	54555737	C	T	Silent	p.L1332L	1
DHX29	HNSC	chr5	54603304	54603304	G	A	Missense_Mutation		1
DHX29	LUAD	chr5	54557208	54557208	C	A	Missense_Mutation	p.W1316C	1
DHX29	BLCA	chr5	54566508	54566508	G	T	Missense_Mutation		1
DHX29	CESC	chr5	54585104	54585104	C	A	Nonsense_Mutation	p.E354*	1
DHX29	THCA	chr5	54565249	54565249	C	T	Missense_Mutation	p.D1096N	1
DHX29	HNSC	chr5	54585191	54585191	C	T	Missense_Mutation		1
DHX29	LIHC	chr5	54586093	54586096	TTGT	-	Frame_Shift_Del	p.286_287del	1
DHX29	KIRC	chr5	54579287	54579287	T	C	Missense_Mutation	p.Q570R	1
DHX29	PRAD	chr5	54570759	54570759	G	A	Missense_Mutation	p.A836V	1
DHX29	SKCM	chr5	54572228	54572228	G	A	Missense_Mutation	p.H765Y	1
DHX29	COAD	chr5	54567971	54567971	A	G	Silent	p.G936G	1
DHX29	UCEC	chr5	54579597	54579597	G	T	Missense_Mutation	p.L467M	1
DHX29	STAD	chr5	54585098	54585098	C	A	Missense_Mutation	p.D356Y	1
DHX29	LGG	chr5	54585244	54585245	AA	-	Frame_Shift_Del	p.L307fs	1
DHX29	LIHC	chr5	54579121	54579121	A	-	Frame_Shift_Del	p.I625fs	1
DHX29	BLCA	chr5	54593119	54593119	T	-	Frame_Shift_Del	p.K123fs	1
DHX29	HNSC	chr5	54569133	54569133	T	A	Silent		1
DHX29	LUAD	chr5	54557319	54557319	A	G	Silent	p.Y1279Y	1
DHX29	BLCA	chr5	54552337	54552337	C	G	Missense_Mutation		1
DHX29	CESC	chr5	54567958	54567958	C	T	Missense_Mutation	p.D941N	1
DHX29	THYM	chr5	54558482	54558482	A	T	Missense_Mutation		1
DHX29	SKCM	chr5	54566425	54566425	G	A	Nonsense_Mutation	p.R992*	1
DHX29	COAD	chr5	54570786	54570786	T	C	Missense_Mutation	p.Q827R	1
DHX29	UCEC	chr5	54589965	54589966	-	T	Frame_Shift_Ins	p.K220fs	1
DHX29	STAD	chr5	54579187	54579187	A	G	Silent	p.T603T	1
DHX29	LIHC	chr5	54581138	54581138	G	-	Frame_Shift_Del	p.R447fs	1
DHX29	LIHC	chr5	54567918	54567918	T	-	Frame_Shift_Del	p.N954fs	1
DHX29	SARC	chr5	54579608	54579608	C	A	Missense_Mutation		1
DHX29	HNSC	chr5	54566425	54566425	G	T	Silent		1
DHX29	LUAD	chr5	54573088	54573088	G	C	Nonsense_Mutation	p.S711*	1
DHX29	BLCA	chr5	54567922	54567922	C	G	Missense_Mutation		1
DHX29	CESC	chr5	54591326	54591326	C	T	Missense_Mutation	p.E178K	1
DHX29	THYM	chr5	54579597	54579597	G	A	Silent	p.L467L	1
DHX29	READ	chr5	54572998	54572998	T	G	Missense_Mutation	p.K741T	1
DHX29	SKCM	chr5	54581572	54581572	G	A	Missense_Mutation	p.P395L	1
DHX29	BLCA	chr5	54563624	54563624	C	A	Missense_Mutation	p.E1107D	1
DHX29	ESCA	chr5	54579423	54579423	C	-	Frame_Shift_Del	p.E525fs	1
DHX29	STAD	chr5	54585143	54585144	-	C	Frame_Shift_Ins	p.F341fs	1
DHX29	STAD	chr5	54591220	54591220	T	C	Missense_Mutation	p.D213G	1
DHX29	UCS	chr5	54570837	54570837	T	C	Missense_Mutation		1
DHX29	LGG	chr5	54586064	54586064	T	C	Missense_Mutation		1
DHX29	LIHC	chr5	54592108	54592108	G	-	Frame_Shift_Del	p.L150fs	1
DHX29	LIHC	chr5	54581683	54581683	T	-	Frame_Shift_Del	p.K359fs	1
DHX29	SARC	chr5	54555739	54555739	G	T	Missense_Mutation		1
DHX29	CESC	chr5	54577247	54577247	G	T	Missense_Mutation		1
DHX29	HNSC	chr5	54591224	54591224	C	G	Missense_Mutation		1
DHX29	LUAD	chr5	54581634	54581635	CC	AA	Missense_Mutation	p.W374F	1
DHX29	SKCM	chr5	54579186	54579186	G	A	Nonsense_Mutation	p.Q604X	1
DHX29	BLCA	chr5	54585110	54585110	C	T	Missense_Mutation		1
DHX29	COAD	chr5	54563594	54563594	T	C	Silent	p.R1117R	1
DHX29	THYM	chr5	54558482	54558482	A	T	Missense_Mutation	p.H1268Q	1
DHX29	LIHC	chr5	54563641	54563641	C	T	Missense_Mutation	p.A1102T	1
DHX29	KIRP	chr5	54591351	54591351	A	G	Silent		1
DHX29	READ	chr5	54579230	54579230	C	T	Missense_Mutation	p.R589Q	1
DHX29	SKCM	chr5	54581573	54581573	G	C	Missense_Mutation	p.P395A	1
DHX29	STAD	chr5	54573111	54573111	C	G	Splice_Site	p.V704_splice	1
DHX29	UCS	chr5	54570837	54570837	T	C	Missense_Mutation	p.E810G	1
DHX29	LGG	chr5	54577289	54577289	T	C	Missense_Mutation		1
DHX29	LUAD	chr5	54572151	54572151	C	A	Missense_Mutation	p.E790D	1
DHX29	LUSC	chr5	54555722	54555722	A	G	Silent	p.D1337D	1
DHX29	BLCA	chr5	54581607	54581607	C	G	Silent		1
DHX29	COAD	chr5	54566275	54566275	G	A	Missense_Mutation	p.R1012C	1
DHX29	LIHC	chr5	54579395	54579396	-	A	Frame_Shift_Ins	p.C534fs	1
DHX29	LIHC	chr5	54555768	54555768	G	-	Frame_Shift_Del	p.P1322fs	1
DHX29	READ	chr5	54558599	54558599	C	T	Silent	p.G1229G	1
DHX29	SKCM	chr5	54557221	54557221	G	A	Missense_Mutation	p.S1312F	1
DHX29	BLCA	chr5	54593198	54593198	C	A	Missense_Mutation	p.R97I	1
DHX29	STAD	chr5	54585143	54585144	-	C	Frame_Shift_Ins	p.N340fs	1
DHX29	LIHC	chr5	54563050	54563050	T	C	Silent		1
DHX29	LIHC	chr5	54565271	54565271	A	-	Frame_Shift_Del	p.F1088fs	1
DHX29	OV	chr5	54627893	54627898	CTTTGT	-	In_Frame_Del		1
DHX29	BLCA	chr5	54603390	54603390	C	A	Missense_Mutation		1
DHX29	COAD	chr5	54572109	54572110	-	C	Frame_Shift_Ins	p.G804fs	1
DHX29	LGG	chr5	54557292	54557292	G	A	Silent	p.T1288T	1
DHX29	LIHC	chr5	54572229	54572229	A	-	Frame_Shift_Del	p.F764fs	1
DHX29	SKCM	chr5	54563028	54563028	G	A	Missense_Mutation	p.R1155C	1
DHX29	BLCA	chr5	54552337	54552337	C	G	Missense_Mutation	p.L1363F	1
DHX29	ESCA	chr5	54565325	54565325	G	T	Silent		1
DHX29	BLCA	chr5	54579357	54579357	C	T	Missense_Mutation		1
DHX29	STAD	chr5	54585144	54585145	-	C	Frame_Shift_Ins	p.N340fs	1
DHX29	LIHC	chr5	54572163	54572163	T	C	Silent		1
DHX29	SARC	chr5	54593194	54593194	A	T	Silent	p.I98I	1
DHX29	KIRC	chr5	54569200	54569201	-	TA	Frame_Shift_Ins	p.K899fs	1
DHX29	OV	chr5	54615167	54615167	G	A	Missense_Mutation		1
DHX29	BLCA	chr5	54593189	54593189	C	G	Missense_Mutation		1
DHX29	COAD	chr5	54579346	54579346	T	C	Silent	p.R550R	1
DHX29	UCEC	chr5	54579436	54579436	G	A	Silent	p.P520P	1
DHX29	LGG	chr5	54563554	54563554	C	T	Missense_Mutation	p.A1131T	1
DHX29	LIHC	chr5	54589854	54589854	T	-	Frame_Shift_Del	p.K257fs	1
DHX29	READ	chr5	54581678	54581678	C	A	Nonsense_Mutation	p.E360X	1
DHX29	SKCM	chr5	54563056	54563056	C	T	Nonsense_Mutation	p.W1145*	1
DHX29	ESCA	chr5	54557317	54557317	G	A	Missense_Mutation		1
DHX29	BLCA	chr5	54579455	54579455	C	G	Missense_Mutation		1
DHX29	CESC	chr5	54570469	54570469	G	C	Nonsense_Mutation		1
DHX29	TGCT	chr5	54557283	54557283	G	A	Silent		1
DHX29	LUAD	chr5	54594436	54594436	C	T	Missense_Mutation	p.D82N	1

Copy number variation (CNV) of DHX29
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across DHX29
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
98251	STAD	TCGA-BR-8678-01A	APH1B	chr15	63571530	+	DHX29	chr5	54573110	-
98251	N/A	FN066230	ARHGAP15	chr2	144407331	+	DHX29	chr5	54552368	-
98251	OV	TCGA-13-0893-01B	CDC20B	chr5	54468416	-	DHX29	chr5	54552368	-
101436	N/A	BQ310859	DHX29	chr5	54577247	-	SVIL	chr10	29926553	-
98251	N/A	EC576205	DYNC2H1	chr11	103156899	-	DHX29	chr5	54552326	-
98251	Non-Cancer	267N	FBXW2	chr9	123555426	-	DHX29	chr5	54577343	-
98251	BRCA	TCGA-A8-A09Q	IL6ST	chr5	55243320	-	DHX29	chr5	54565465	-
98251	BRCA	TCGA-A8-A09Q-01A	IL6ST	chr5	55243321	-	DHX29	chr5	54565465	-
98251	BLCA	TCGA-BL-A13J-01A	PPAP2A	chr5	54763697	-	DHX29	chr5	54572234	-
98251	UCEC	TCGA-EO-A1Y7-01A	PPAP2A	chr5	54830400	-	DHX29	chr5	54558760	-
98251	LUAD	TCGA-50-6673	SLC39A11	chr17	71027694	-	DHX29	chr5	54552368	-
98251	LUAD	TCGA-50-6673-01A	SLC39A11	chr17	71027695	-	DHX29	chr5	54552368	-
98256	KIRC	TCGA-B0-4819-01A	VPS13A	chr9	79875140	+	DHX29	chr5	54573110	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
HNSC	DHX29	0.000473504791260916	0.013
KIRP	DHX29	0.000646230674084738	0.017
TGCT	DHX29	0.00777527603899963	0.2
READ	DHX29	0.020722022661174	0.52

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRC	DHX29	0.00334125095419007	0.11
BRCA	DHX29	0.00417939049704915	0.13
OV	DHX29	0.0060252203377797	0.19
UCS	DHX29	0.0193802909385448	0.58

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source