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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: RPL13 (NCBI Gene ID:6137)

Gene Summary

Gene Summary

Gene Information	Gene Name: RPL13
	Gene ID: 6137
	Gene Symbol	RPL13
	Gene ID	6137
	Gene Name	ribosomal protein L13
	Synonyms	BBC1\|D16S444E\|D16S44E\|L13\|SEMDIST
	Cytomap	16q24.3\|17p11.2
	Type of Gene	protein-coding
	Description	60S ribosomal protein L13OK/SW-cl.46breast basic conserved 1breast basic conserved protein 1large ribosomal subunit protein eL13
	Modification date	20200313
	UniProtAcc	P26373

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0002181	Cytoplasmic translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
RPL13	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'RPL13[title] AND translation [title] AND human.'

Gene	Title	PMID
RPL13	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000567815	89627361	89627471	5CDS-5UTR
ENST00000311528	89627634	89627776	Frame-shift
ENST00000393099	89627634	89627776	Frame-shift
ENST00000567815	89627634	89627776	Frame-shift
ENST00000311528	89628742	89628799	In-frame
ENST00000393099	89628742	89628799	In-frame
ENST00000567815	89628742	89628799	In-frame

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000567815	89628742	89628799	729	459	515	211	140	159
ENST00000311528	89628742	89628799	2228	497	553	211	140	159
ENST00000393099	89628742	89628799	2402	670	726	211	140	159

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc	Exon skip start (AA)	Exon Skip end (AA)	Function feature start (AA)	Function feature end (AA)	Functional feature type	Functional feature desc.
P26373	140	159	1	211	Chain	ID=PRO_0000192919;Note=60S ribosomal protein L13
P26373	140	159	1	211	Chain	ID=PRO_0000192919;Note=60S ribosomal protein L13
P26373	140	159	1	211	Chain	ID=PRO_0000192919;Note=60S ribosomal protein L13
P26373	140	159	145	145	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:28112733;Dbxref=PMID:28112733
P26373	140	159	145	145	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:28112733;Dbxref=PMID:28112733
P26373	140	159	145	145	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:28112733;Dbxref=PMID:28112733

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
COAD	RPL13	2.11745314482912	0.000465095043182374
STAD	RPL13	-1.17078722854876	0.0294188209809363
KICH	RPL13	-5.95618047175394	0.0366820693016052
KIRC	RPL13	-3.44015571111292	2.58914497097505e-10

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
PRAD	RPL13	-0.047426892	0.018641906
UCS	RPL13	-0.033302629	0.029612994
LUSC	RPL13	0.067351674	0.032199071
ESCA	RPL13	-0.06353147	0.046801789

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with RPL13 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
CHOL	Cell metabolism gene	RPL13	SNRPD2	0.825255153	3.10E-12
DLBC	Cell metabolism gene	RPL13	GEMIN7	0.803170272	6.48E-12
DLBC	Cell metabolism gene	RPL13	PGLS	0.814485856	1.89E-12
DLBC	Cell metabolism gene	RPL13	TOMM22	0.829690498	3.15E-13
DLBC	Cell metabolism gene	RPL13	TIMM9	0.837502312	1.17E-13
DLBC	Cell metabolism gene	RPL13	SNRPD2	0.851699311	1.68E-14
DLBC	Cell metabolism gene	RPL13	NME2	0.854020063	1.20E-14
DLBC	Cell metabolism gene	RPL13	PFDN5	0.865485094	2.08E-15
DLBC	Cell metabolism gene	RPL13	FAU	0.868479445	1.28E-15
DLBC	Cell metabolism gene	RPL13	GFER	0.874401047	4.75E-16
DLBC	CGC	RPL13	NACA	0.848587282	2.61E-14
DLBC	TF	RPL13	ZNF581	0.817328156	1.37E-12
DLBC	TF	RPL13	THAP7	0.822531691	7.48E-13
DLBC	TF	RPL13	NME2	0.854020063	1.20E-14
DLBC	TSG	RPL13	GLTSCR2	0.817435646	1.35E-12
DLBC	TSG	RPL13	GADD45GIP1	0.840714763	7.67E-14
DLBC	TSG	RPL13	GNB2L1	0.915924823	7.36E-20
KICH	Cell metabolism gene	RPL13	PGLS	0.806627378	4.92E-22
KICH	TSG	RPL13	GLTSCR2	0.856201562	2.92E-27
KIRP	Cell metabolism gene	RPL13	PGLS	0.839058208	7.28E-87
KIRP	Cell metabolism gene	RPL13	FAU	0.863027771	3.25E-97
KIRP	Epifactor	RPL13	TAF10	0.813748478	1.23E-77
KIRP	TSG	RPL13	GADD45GIP1	0.84565145	1.56E-89
LAML	Cell metabolism gene	RPL13	FAU	0.81275711	5.65E-42
LAML	TSG	RPL13	GLTSCR2	0.82682318	1.36E-44
LGG	Cell metabolism gene	RPL13	FAU	0.883441218	5.61E-176
LGG	TSG	RPL13	AIP	0.806916717	7.97E-123
LGG	TSG	RPL13	GNB2L1	0.810218026	1.35E-124
LGG	TSG	RPL13	GAS5	0.816302117	5.99E-128
PAAD	Cell metabolism gene	RPL13	FAU	0.871466985	6.76E-58
PCPG	Cell metabolism gene	RPL13	FAU	0.814089305	1.56E-45
PCPG	Cell metabolism gene	RPL13	PFDN5	0.870859763	5.81E-59
PCPG	TSG	RPL13	GLTSCR2	0.835493893	5.48E-50
PCPG	TSG	RPL13	GNB2L1	0.846323138	1.71E-52
PRAD	Cell metabolism gene	RPL13	PGLS	0.80621986	5.05E-127
PRAD	Cell metabolism gene	RPL13	PFDN5	0.807801667	6.78E-128
PRAD	Cell metabolism gene	RPL13	MPST	0.811903235	3.40E-130
PRAD	Cell metabolism gene	RPL13	APRT	0.816643851	6.35E-133
PRAD	Cell metabolism gene	RPL13	POLR2I	0.839822263	1.65E-147
PRAD	Cell metabolism gene	RPL13	FAU	0.848832507	8.03E-154
PRAD	Epifactor	RPL13	FBL	0.820654702	2.70E-135
PRAD	IUPHAR	RPL13	MPST	0.811903235	3.40E-130
PRAD	TF	RPL13	ZNF358	0.819946964	7.14E-135
PRAD	TF	RPL13	ZNF524	0.847065604	1.50E-152
PRAD	TSG	RPL13	GLTSCR2	0.821752991	5.91E-136
PRAD	TSG	RPL13	GADD45GIP1	0.827371614	2.11E-139
THCA	Cell metabolism gene	RPL13	POLR2I	0.817064688	1.93E-138
THCA	Cell metabolism gene	RPL13	SNRPD2	0.840517578	7.59E-154
THCA	Cell metabolism gene	RPL13	PGLS	0.844501499	1.03E-156
THCA	Cell metabolism gene	RPL13	FAU	0.891896024	1.36E-198
THCA	CGC	RPL13	MAP2K2	0.824836396	2.74E-143
THCA	Epifactor	RPL13	TAF10	0.833639456	4.43E-149
THCA	IUPHAR	RPL13	MAP2K2	0.824836396	2.74E-143
THCA	Kinase	RPL13	MAP2K2	0.824836396	2.74E-143
THCA	TF	RPL13	ZNF358	0.816365859	5.14E-138
THCA	TF	RPL13	ZNF524	0.856642857	5.73E-166
THCA	TSG	RPL13	AIP	0.809548139	5.77E-134
THCA	TSG	RPL13	GNB2L1	0.815381897	2.02E-137
THCA	TSG	RPL13	GADD45GIP1	0.836030259	1.03E-150
THCA	TSG	RPL13	GLTSCR2	0.837964713	4.73E-152
THYM	Cell metabolism gene	RPL13	DGUOK	0.800210311	2.04E-28
THYM	Cell metabolism gene	RPL13	FPGS	0.808687799	1.99E-29
THYM	Cell metabolism gene	RPL13	PSMB1	0.810180304	1.30E-29
THYM	Cell metabolism gene	RPL13	SNRPD3	0.812133242	7.45E-30
THYM	Cell metabolism gene	RPL13	PSMD13	0.814999213	3.25E-30
THYM	Cell metabolism gene	RPL13	PSMB10	0.82039184	6.53E-31
THYM	Cell metabolism gene	RPL13	LSM2	0.82560845	1.32E-31
THYM	Cell metabolism gene	RPL13	SSR2	0.827346744	7.62E-32
THYM	Cell metabolism gene	RPL13	ACOT8	0.828038279	6.12E-32
THYM	Cell metabolism gene	RPL13	GUK1	0.829863254	3.42E-32
THYM	Cell metabolism gene	RPL13	PHKG2	0.831155085	2.25E-32
THYM	Cell metabolism gene	RPL13	PSMC3	0.832224074	1.59E-32
THYM	Cell metabolism gene	RPL13	APOA1	0.832319236	1.54E-32
THYM	Cell metabolism gene	RPL13	IDH3G	0.83271792	1.36E-32
THYM	Cell metabolism gene	RPL13	PSMB3	0.835849636	4.81E-33
THYM	Cell metabolism gene	RPL13	TIMM13	0.837556805	2.71E-33
THYM	Cell metabolism gene	RPL13	PSMB7	0.838877103	1.73E-33
THYM	Cell metabolism gene	RPL13	SLC27A5	0.842899173	4.32E-34
THYM	Cell metabolism gene	RPL13	TIMM50	0.847868589	7.33E-35
THYM	Cell metabolism gene	RPL13	DPM3	0.848423896	5.99E-35
THYM	Cell metabolism gene	RPL13	MVD	0.853108706	1.05E-35
THYM	Cell metabolism gene	RPL13	TIMM8B	0.853675237	8.51E-36
THYM	Cell metabolism gene	RPL13	UROD	0.854524522	6.16E-36
THYM	Cell metabolism gene	RPL13	DPM2	0.856132845	3.33E-36
THYM	Cell metabolism gene	RPL13	POLR2I	0.856838101	2.53E-36
THYM	Cell metabolism gene	RPL13	POLR2F	0.859047508	1.07E-36
THYM	Cell metabolism gene	RPL13	POLR2J	0.87225756	4.38E-39
THYM	Cell metabolism gene	RPL13	SNRPD2	0.883637179	2.31E-41
THYM	Cell metabolism gene	RPL13	PGLS	0.896754847	2.63E-44
THYM	Cell metabolism gene	RPL13	PFDN5	0.899492138	5.71E-45
THYM	Cell metabolism gene	RPL13	APRT	0.90285636	8.21E-46
THYM	Cell metabolism gene	RPL13	FAU	0.942600792	5.30E-59
THYM	CGC	RPL13	SDHAF2	0.80423338	6.86E-29
THYM	CGC	RPL13	MAP2K2	0.811568623	8.77E-30
THYM	CGC	RPL13	MGMT	0.823001324	2.95E-31
THYM	CGC	RPL13	TFPT	0.853856711	7.94E-36
THYM	CGC	RPL13	RBM10	0.85550333	4.24E-36
THYM	Epifactor	RPL13	CXXC1	0.802295971	1.16E-28
THYM	Epifactor	RPL13	HIST2H2AC	0.803197358	9.10E-29
THYM	Epifactor	RPL13	SS18L2	0.809096037	1.77E-29
THYM	Epifactor	RPL13	PAF1	0.810379397	1.23E-29
THYM	Epifactor	RPL13	PPP4C	0.816582703	2.04E-30
THYM	Epifactor	RPL13	TADA3	0.816859358	1.88E-30
THYM	Epifactor	RPL13	PRMT7	0.818285686	1.23E-30
THYM	Epifactor	RPL13	RUVBL2	0.820039681	7.27E-31
THYM	Epifactor	RPL13	MBD3	0.825291803	1.45E-31
THYM	Epifactor	RPL13	C17orf49	0.833297493	1.12E-32
THYM	Epifactor	RPL13	FBL	0.843866992	3.07E-34
THYM	Epifactor	RPL13	TFPT	0.853856711	7.94E-36
THYM	Epifactor	RPL13	SIRT6	0.857196586	2.20E-36
THYM	Epifactor	RPL13	DMAP1	0.862257602	2.96E-37
THYM	Epifactor	RPL13	PRPF31	0.866714701	4.72E-38
THYM	Epifactor	RPL13	BRMS1	0.868145514	2.58E-38
THYM	Epifactor	RPL13	CCDC101	0.882012686	5.04E-41
THYM	Epifactor	RPL13	INO80E	0.882632647	3.74E-41
THYM	Epifactor	RPL13	ZNHIT1	0.896395828	3.21E-44
THYM	Epifactor	RPL13	TAF10	0.897176544	2.09E-44
THYM	IUPHAR	RPL13	CSNK2B	0.801576384	1.41E-28
THYM	IUPHAR	RPL13	CDK10	0.80429588	6.74E-29
THYM	IUPHAR	RPL13	PSMB1	0.810180304	1.30E-29
THYM	IUPHAR	RPL13	MAP2K2	0.811568623	8.77E-30
THYM	IUPHAR	RPL13	SIRT3	0.815540952	2.77E-30
THYM	IUPHAR	RPL13	PRMT7	0.818285686	1.23E-30
THYM	IUPHAR	RPL13	PHKG2	0.831155085	2.25E-32
THYM	IUPHAR	RPL13	MMP24	0.832001096	1.71E-32
THYM	IUPHAR	RPL13	SLC27A5	0.842899173	4.32E-34
THYM	IUPHAR	RPL13	MVD	0.853108706	1.05E-35
THYM	IUPHAR	RPL13	SIRT6	0.857196586	2.20E-36
THYM	Kinase	RPL13	CDK10	0.80429588	6.74E-29
THYM	Kinase	RPL13	MAP2K2	0.811568623	8.77E-30
THYM	Kinase	RPL13	PHKG2	0.831155085	2.25E-32
THYM	TF	RPL13	CXXC1	0.802295971	1.16E-28
THYM	TF	RPL13	USF2	0.802399332	1.13E-28
THYM	TF	RPL13	AKAP8L	0.809471961	1.59E-29
THYM	TF	RPL13	ZNF394	0.812784066	6.18E-30
THYM	TF	RPL13	ZNF524	0.821632141	4.48E-31
THYM	TF	RPL13	RBCK1	0.821734741	4.35E-31
THYM	TF	RPL13	ZNF32	0.823679976	2.39E-31
THYM	TF	RPL13	MBD3	0.825291803	1.45E-31
THYM	TF	RPL13	ZNF444	0.837181496	3.08E-33
THYM	TF	RPL13	ZNF580	0.838232257	2.16E-33
THYM	TF	RPL13	ZNF787	0.839646095	1.33E-33
THYM	TF	RPL13	ZNF688	0.846744784	1.10E-34
THYM	TF	RPL13	THYN1	0.848520505	5.78E-35
THYM	TF	RPL13	DRAP1	0.85024497	3.07E-35
THYM	TF	RPL13	ZNF428	0.851263305	2.10E-35
THYM	TF	RPL13	THAP7	0.863281286	1.95E-37
THYM	TF	RPL13	THAP3	0.867990432	2.76E-38
THYM	TSG	RPL13	SIRT3	0.815540952	2.77E-30
THYM	TSG	RPL13	HTRA2	0.818078152	1.31E-30
THYM	TSG	RPL13	GABARAP	0.82141503	4.79E-31
THYM	TSG	RPL13	PARK7	0.82583644	1.22E-31
THYM	TSG	RPL13	AIP	0.831880483	1.78E-32
THYM	TSG	RPL13	TSSC4	0.842785645	4.49E-34
THYM	TSG	RPL13	NPRL2	0.847067738	9.80E-35
THYM	TSG	RPL13	SIRT6	0.857196586	2.20E-36
THYM	TSG	RPL13	GADD45GIP1	0.862197212	3.03E-37
THYM	TSG	RPL13	BRMS1	0.868145514	2.58E-38
THYM	TSG	RPL13	GNB2L1	0.89040961	7.77E-43
THYM	TSG	RPL13	GLTSCR2	0.917760933	5.89E-50
UCEC	Cell metabolism gene	RPL13	PFDN5	0.808419428	1.09E-47
UCS	Cell metabolism gene	RPL13	DGUOK	0.800210311	2.04E-28
UCS	Cell metabolism gene	RPL13	FPGS	0.808687799	1.99E-29
UCS	Cell metabolism gene	RPL13	PSMB1	0.810180304	1.30E-29
UCS	Cell metabolism gene	RPL13	SNRPD3	0.812133242	7.45E-30
UCS	Cell metabolism gene	RPL13	PSMD13	0.814999213	3.25E-30
UCS	Cell metabolism gene	RPL13	PSMB10	0.82039184	6.53E-31
UCS	Cell metabolism gene	RPL13	LSM2	0.82560845	1.32E-31
UCS	Cell metabolism gene	RPL13	SSR2	0.827346744	7.62E-32
UCS	Cell metabolism gene	RPL13	ACOT8	0.828038279	6.12E-32
UCS	Cell metabolism gene	RPL13	GUK1	0.829863254	3.42E-32
UCS	Cell metabolism gene	RPL13	PHKG2	0.831155085	2.25E-32
UCS	Cell metabolism gene	RPL13	PSMC3	0.832224074	1.59E-32
UCS	Cell metabolism gene	RPL13	APOA1	0.832319236	1.54E-32
UCS	Cell metabolism gene	RPL13	IDH3G	0.83271792	1.36E-32
UCS	Cell metabolism gene	RPL13	PSMB3	0.835849636	4.81E-33
UCS	Cell metabolism gene	RPL13	TIMM13	0.837556805	2.71E-33
UCS	Cell metabolism gene	RPL13	PSMB7	0.838877103	1.73E-33
UCS	Cell metabolism gene	RPL13	SLC27A5	0.842899173	4.32E-34
UCS	Cell metabolism gene	RPL13	TIMM50	0.847868589	7.33E-35
UCS	Cell metabolism gene	RPL13	DPM3	0.848423896	5.99E-35
UCS	Cell metabolism gene	RPL13	MVD	0.853108706	1.05E-35
UCS	Cell metabolism gene	RPL13	TIMM8B	0.853675237	8.51E-36
UCS	Cell metabolism gene	RPL13	UROD	0.854524522	6.16E-36
UCS	Cell metabolism gene	RPL13	DPM2	0.856132845	3.33E-36
UCS	Cell metabolism gene	RPL13	POLR2I	0.856838101	2.53E-36
UCS	Cell metabolism gene	RPL13	POLR2F	0.859047508	1.07E-36
UCS	Cell metabolism gene	RPL13	POLR2J	0.87225756	4.38E-39
UCS	Cell metabolism gene	RPL13	SNRPD2	0.883637179	2.31E-41
UCS	Cell metabolism gene	RPL13	PGLS	0.896754847	2.63E-44
UCS	Cell metabolism gene	RPL13	PFDN5	0.899492138	5.71E-45
UCS	Cell metabolism gene	RPL13	APRT	0.90285636	8.21E-46
UCS	Cell metabolism gene	RPL13	FAU	0.942600792	5.30E-59
UCS	CGC	RPL13	SDHAF2	0.80423338	6.86E-29
UCS	CGC	RPL13	MAP2K2	0.811568623	8.77E-30
UCS	CGC	RPL13	MGMT	0.823001324	2.95E-31
UCS	CGC	RPL13	TFPT	0.853856711	7.94E-36
UCS	CGC	RPL13	RBM10	0.85550333	4.24E-36
UCS	Epifactor	RPL13	CXXC1	0.802295971	1.16E-28
UCS	Epifactor	RPL13	HIST2H2AC	0.803197358	9.10E-29
UCS	Epifactor	RPL13	SS18L2	0.809096037	1.77E-29
UCS	Epifactor	RPL13	PAF1	0.810379397	1.23E-29
UCS	Epifactor	RPL13	PPP4C	0.816582703	2.04E-30
UCS	Epifactor	RPL13	TADA3	0.816859358	1.88E-30
UCS	Epifactor	RPL13	PRMT7	0.818285686	1.23E-30
UCS	Epifactor	RPL13	RUVBL2	0.820039681	7.27E-31
UCS	Epifactor	RPL13	MBD3	0.825291803	1.45E-31
UCS	Epifactor	RPL13	C17orf49	0.833297493	1.12E-32
UCS	Epifactor	RPL13	FBL	0.843866992	3.07E-34
UCS	Epifactor	RPL13	TFPT	0.853856711	7.94E-36
UCS	Epifactor	RPL13	SIRT6	0.857196586	2.20E-36
UCS	Epifactor	RPL13	DMAP1	0.862257602	2.96E-37
UCS	Epifactor	RPL13	PRPF31	0.866714701	4.72E-38
UCS	Epifactor	RPL13	BRMS1	0.868145514	2.58E-38
UCS	Epifactor	RPL13	CCDC101	0.882012686	5.04E-41
UCS	Epifactor	RPL13	INO80E	0.882632647	3.74E-41
UCS	Epifactor	RPL13	ZNHIT1	0.896395828	3.21E-44
UCS	Epifactor	RPL13	TAF10	0.897176544	2.09E-44
UCS	IUPHAR	RPL13	CSNK2B	0.801576384	1.41E-28
UCS	IUPHAR	RPL13	CDK10	0.80429588	6.74E-29
UCS	IUPHAR	RPL13	PSMB1	0.810180304	1.30E-29
UCS	IUPHAR	RPL13	MAP2K2	0.811568623	8.77E-30
UCS	IUPHAR	RPL13	SIRT3	0.815540952	2.77E-30
UCS	IUPHAR	RPL13	PRMT7	0.818285686	1.23E-30
UCS	IUPHAR	RPL13	PHKG2	0.831155085	2.25E-32
UCS	IUPHAR	RPL13	MMP24	0.832001096	1.71E-32
UCS	IUPHAR	RPL13	SLC27A5	0.842899173	4.32E-34
UCS	IUPHAR	RPL13	MVD	0.853108706	1.05E-35
UCS	IUPHAR	RPL13	SIRT6	0.857196586	2.20E-36
UCS	Kinase	RPL13	CDK10	0.80429588	6.74E-29
UCS	Kinase	RPL13	MAP2K2	0.811568623	8.77E-30
UCS	Kinase	RPL13	PHKG2	0.831155085	2.25E-32
UCS	TF	RPL13	CXXC1	0.802295971	1.16E-28
UCS	TF	RPL13	USF2	0.802399332	1.13E-28
UCS	TF	RPL13	AKAP8L	0.809471961	1.59E-29
UCS	TF	RPL13	ZNF394	0.812784066	6.18E-30
UCS	TF	RPL13	ZNF524	0.821632141	4.48E-31
UCS	TF	RPL13	RBCK1	0.821734741	4.35E-31
UCS	TF	RPL13	ZNF32	0.823679976	2.39E-31
UCS	TF	RPL13	MBD3	0.825291803	1.45E-31
UCS	TF	RPL13	ZNF444	0.837181496	3.08E-33
UCS	TF	RPL13	ZNF580	0.838232257	2.16E-33
UCS	TF	RPL13	ZNF787	0.839646095	1.33E-33
UCS	TF	RPL13	ZNF688	0.846744784	1.10E-34
UCS	TF	RPL13	THYN1	0.848520505	5.78E-35
UCS	TF	RPL13	DRAP1	0.85024497	3.07E-35
UCS	TF	RPL13	ZNF428	0.851263305	2.10E-35
UCS	TF	RPL13	THAP7	0.863281286	1.95E-37
UCS	TF	RPL13	THAP3	0.867990432	2.76E-38
UCS	TSG	RPL13	SIRT3	0.815540952	2.77E-30
UCS	TSG	RPL13	HTRA2	0.818078152	1.31E-30
UCS	TSG	RPL13	GABARAP	0.82141503	4.79E-31
UCS	TSG	RPL13	PARK7	0.82583644	1.22E-31
UCS	TSG	RPL13	AIP	0.831880483	1.78E-32
UCS	TSG	RPL13	TSSC4	0.842785645	4.49E-34
UCS	TSG	RPL13	NPRL2	0.847067738	9.80E-35
UCS	TSG	RPL13	SIRT6	0.857196586	2.20E-36
UCS	TSG	RPL13	GADD45GIP1	0.862197212	3.03E-37
UCS	TSG	RPL13	BRMS1	0.868145514	2.58E-38
UCS	TSG	RPL13	GNB2L1	0.89040961	7.77E-43
UCS	TSG	RPL13	GLTSCR2	0.917760933	5.89E-50
UVM	Cell metabolism gene	RPL13	SLC25A6	0.830084006	1.77E-21
UVM	Cell metabolism gene	RPL13	MVD	0.846766978	4.40E-23
UVM	Cell metabolism gene	RPL13	FAU	0.86422752	5.56E-25
UVM	Epifactor	RPL13	FBL	0.858926886	2.23E-24
UVM	IUPHAR	RPL13	SLC25A6	0.830084006	1.77E-21
UVM	IUPHAR	RPL13	MVD	0.846766978	4.40E-23
UVM	IUPHAR	RPL13	CSNK2A2	0.86062317	1.44E-24
UVM	Kinase	RPL13	CSNK2A2	0.86062317	1.44E-24
UVM	TF	RPL13	ZFPM1	0.80891771	1.12E-19
UVM	TSG	RPL13	GNB2L1	0.825420322	4.64E-21
UVM	TSG	RPL13	GLTSCR2	0.896160416	2.99E-29

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
KIRP	RPL13	RPL18A	-1.51651392808885	0.00016188295558095
KICH	RPL13	RPS27A	1.75396693785956	0.000187873840332031
KIRP	RPL13	RPS16	-1.35957043617517	0.00019507110118866
COAD	RPL13	RPS3	1.48730375143014	0.000411599874496461
KIRP	RPL13	RPS11	-1.01861570565103	0.00105937570333481
LIHC	RPL13	RPL8	-4.84588284974558	0.00110314154326131
PRAD	RPL13	RPL18A	1.40600175748499	0.00205137828390396
KICH	RPL13	RPL19	1.36901182894089	0.00250792503356934
KICH	RPL13	RPS12	1.26997381758431	0.00308787822723389
LUAD	RPL13	RPL19	-1.31398026615725	0.00993159558412698
THCA	RPL13	RPS16	-6.16322798156577	0.0115764821363307
BLCA	RPL13	RPS12	-1.47804673440421	0.0204124450683594
BLCA	RPL13	RPS27A	-1.04747470069188	0.0258216857910156
HNSC	RPL13	RPS3	-4.73505819095135	0.0273726439852453
COAD	RPL13	RPS11	1.35307548998204	0.0312207043170929
LUSC	RPL13	RPL19	-2.14669889516666	0.044366810398747
KIRC	RPL13	RPL19	-2.73485271276676	1.33980982873695e-10
BRCA	RPL13	RPS12	-4.91239327478244	1.85340619742495e-09
KIRP	RPL13	RPL37	-1.17421621947139	2.26888805627823e-05
KIRC	RPL13	RPL35	-1.06475238059392	2.72286325678163e-08
KIRC	RPL13	RPL8	-1.18252459971773	5.64962994208288e-07
KIRP	RPL13	RPL8	-1.53003692350119	6.0301274061203e-05
KIRC	RPL13	RPS16	-1.66149869889384	7.8509870430991e-09
BRCA	RPL13	RPS27A	-4.28512148200424	7.8788217967112e-14
KIRC	RPL13	RPL37	-2.87198822058464	8.03913394748564e-12
KIRP	RPL13	RPL35	-1.52981101975496	9.0546440333128e-05
KIRC	RPL13	RPS3	-1.29560847926387	9.05905681935088e-10
KIRC	RPL13	RPL18A	-4.43079304960843	9.2516163152192e-11

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with RPL13

CDC5L, SMN1, DCC, HDAC5, NOP56, RICTOR, EBNA-LP, MAPKAPK5, ILK, CSNK2B, RELA, TK1, MAP2K3, DAXX, ANXA7, RAD21, TCF3, SPP1, TERF2, NFX1, CUL3, CUL4B, CUL2, CDK2, CUL1, COPS5, CAND1, RPL12, RPS16, RPS25, RPL10A, RPL11, RPL14, RPL15, RPL18, RPL19, RPL21, RPL23, RPL24, RPL27A, RPL37A, RPL4, RPL5, RPL6, RPL7A, RPS23, RPS2, RPS3A, RPS3, RPS4X, RPS6, RPS8, RPSA, RPL23A, RPS28, RPL7, RPL22, RPS20, RPL30, RPLP0, RPS7, RPS13, RPL36, RPS15A, RPL17, RPS21, FAU, ILF3, PABPC1, GNB2L1, RPLP0P6, RPS27L, MYL12A, ESR1, MAGOH, EIF4A3, MYC, FN1, VCAM1, CSNK2A1, UBL4A, ITGA4, PAN2, CD81, IGSF8, ICAM1, UPF2, TARDBP, PARK2, AIMP1, DARS, MARS, QARS, EEF1E1, EIF2S1, RPL26, STAU1, CEP250, NEDD1, TP53, TUBG1, TUBGCP4, VCP, HUWE1, CEP70, MOV10, NXF1, CUL7, OBSL1, EBNA1BP2, GTF3C2, MRPS9, PTCD3, GTF3C3, RANBP6, IPO5, MRPS27, MRPL9, RPL26L1, TRO, MRPL32, MRPL48, MRPL40, MRPL1, GTF3C1, MRPS5, MRPL28, SENP3, TUBA8, TEX10, RBM34, VPRBP, MRPL50, MRPL27, MRPL55, MRPL47, MRPL16, MRPS24, MRPL38, NSUN4, ICT1, MRPL13, PELP1, MRPL17, MRPS33, GADD45GIP1, MRPL30, NSA2, MRPL20, PPAN-P2RY11, MRPS18A, MRPL42, MRPL18, MRPS30, MRPL34, THAP7, ZNF317, RPS6KB2, NTRK1, RPL10, RPL18A, RPL3, RPL31, RPL35, RPL38, RPL3L, RPL8, RPS10, RPS11, RPS12, RPS19, UBA52, RPL13A, RPL27, RPL28, RPL34, RPL35A, RPL9, RPLP1, RPS14, RPS15, RPS18, LOC101929876, RPS26, RPS27, RPS5, RPS9, SFN, PTEN, SRPK2, AHSA1, HNRNPU, NPM1, EXOSC4, Eif3a, Eif3e, Srp72, Rrbp1, GAN, TRIM29, MCM2, NF2, Ksr1, RC3H1, C3orf17, ZNF746, PPP1CA, PPP1CC, CNBP, MECP2, SART3, MAGEB10, KIAA0020, ZC3HAV1, KNOP1, ZNF512, NUFIP1, RRS1, NCL, CYLD, INO80B, TRIM25, C14orf178, CARS, DCTN2, GTF2E1, NUTF2, RPL13, TMPO, IGFBP4, BMP4, CTNNB1, TGFB1, PRPF8, EFTUD2, AAR2, PIH1D1, CHD3, RNF4, CHD4, RNF31, TNF, SPDL1, RIOK1, FGF11, HEXIM1, MEPCE, LARP7, KCMF1, SNAI1, RECQL4, GPC1, REST, CDK9, HIST1H3A, GRWD1, METTL3, METTL14, RC3H2, PHB, FAF1, RBX1, NR2C2, UCHL3, HDAC2, VRK1, VRK3, HIST1H4A, DYRK1A, SNRNP70, CDC14A, MTMR2, PTPN6, ITFG1, ARAF, HMGB1, BIRC3, WWP2, MATR3, Dnajc17, HTT, CMTR1, ARIH2, PLEKHA4, PINK1, YAP1, TFCP2, FANCD2, HCVgp1, ZC3H18, MAP3K14, RAB5A, KMT2A, RAI1, GALNT6, HERC2, BRIX1, E, M, nsp13, nsp14, nsp4, nsp5, nsp6, ORF3a, ORF6, ORF7a, ORF7b, nsp3, ORF10, ORF14, ORF8, ERCC6, DUX4, CIT, ANLN, AURKB, CHMP4B, CHMP4C, ECT2, KIF14, KIF20A, KIF23, PRC1, FASN, LRRC59, NDN, RBM45, Apc2, RBM39, FBP1, LGALS9, GSK3A, GSK3B, IFI16, RIN3, DNAJC2, DNAJC1, KDF1, OGT, UFL1, DDRGK1, POLR2C, RPS24, TRIM37, ATG3, FZR1, WDR5, PAGE4, NUDCD2, NAA40, ZNF668, PAPD5, PRKRA, TAF1A, TAF1C, ZCCHC7, NOP2, ADARB1, CENPL, BEND7, GZF1, DDX21, CENPU, FTSJ3, UTP3, MRPL15, BMS1, ITGB3BP, DKC1, ZNF22, RRP8, NIP7, RBMX2, CENPQ, MPHOSPH10, RBM28, ZNF142, C7orf50, MRPL45, AATF, ZNF48, DDX56, RSBN1, CENPN, ZBTB47, NPM3, GLE1, CCDC137, RPL7L1, CENPI, DAP3, PRDM10, ZFP62, GLTSCR2, TTF1, MRPS25, WHSC1, MRPS10, ZBTB41, SF3B1, RRP15, HERC5, CENPH, ZNF646, DDX10, PRDM15, CEBPZ, LYAR, C8orf33, MRPS26, HP1BP3, MRPL10, NOL10, NAT10, STAU2, CCDC140, GLYR1, SRSF6, SRSF5, MRPL11, SURF6, MRPS35, HIST1H2AG, DDX54, NMNAT1, PATZ1, CTCF, REXO4, GNL2, YBX1, DDX31, MRPL52, SRPK3, LLPH, ZNF770, MYBBP1A, NOC3L, MRPL23, DDX27, IMP4, YTHDC2, MRPS7, BOP1, DDX24, ZC3H10, RSL1D1, RPF2, RPL32, ZFR, NOL12, DICER1, TOPORS, ZFP91, KRI1, PDCD11, MRPL3, PHF6, DHX36, NOC2L, HJURP, ARRB1, ZBTB11, ZNF865, PURA, PURB, C1orf35, MRPS18C, IGF2BP3, ZNF813, HIST2H2AB, TBL2, FAM111A, TRIM56, ZC3H3, SMARCD1, NKRF, DDX51, CDK13, ZCCHC6, DDX55, FCF1, NOM1, RPS4Y2, TARBP2, GPATCH4, PRPF4B, RPLP2, WDR74, DUSP11, NOL8, PRPF40A, SPATA5L1, ZNF845, NGDN, URB2, THAP3, UTP14A, EPB41L5, ZNF771, ZNF791, ZNF768, SDAD1, SRPK1, C14orf169, RRP12, ZFP90, RSBN1L, URB1, MRPS34, SREK1, ZNF354A, RPF1, ZNF766, SRRM1, BUD13, NOP10, SPATS2L, TSPYL1, ZNF638, IMP3, POP1, IFIT5, TAF1B, RSL24D1, SMARCA5, MRPS31, LUC7L, ZNF346, SPTY2D1, DDX50, MINA, SRP72, FGFBP1, GNL3, ZNF16, ZNF629, DDX18, MRPL41, GAR1, RFC1, SRP68, CDK12, MAGEB2, MRPS14, OASL, CDKN2AIP, YBX3, RBM19, HIST2H2AC, MAP7D1, NKTR, SPATS2, ABT1, NUPL2, ZNF485, EPB41L4B, DHX30, ZNF574, TSPYL2, NOA1, POLRMT, TAF1D, PAK1IP1, U2SURP, WDR12, UTP23, XRN1, C10orf2, NIFK, SPATA5, RRP1B, TBP, PRKRIR, NOP16, UTP18, MRPL51, GTPBP10, ZBTB24, SON, GTPBP4, DHX37, MAK16, SPRTN, FBXW7, PRRC2B, NLRP7, RCHY1, CCNF, N, RB1CC1,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
RPL13	chr16	89627460	T	G	single_nucleotide_variant	Benign	Spondyloepimetaphyseal_dysplasia,_Isidor-Toutain_type	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPL13	chr16	89627671	C	T	single_nucleotide_variant	Benign	Spondyloepimetaphyseal_dysplasia,_Isidor-Toutain_type	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPL13	chr16	89628800	G	A	single_nucleotide_variant	Pathogenic	Spondyloepimetaphyseal_dysplasia\|Spondyloepimetaphyseal_dysplasia,_Isidor-Toutain_type	SO:0001575\|splice_donor_variant	SO:0001575\|splice_donor_variant
RPL13	chr16	89628800	G	T	single_nucleotide_variant	Pathogenic	Spondyloepimetaphyseal_dysplasia\|Spondyloepimetaphyseal_dysplasia,_Isidor-Toutain_type	SO:0001575\|splice_donor_variant	SO:0001575\|splice_donor_variant
RPL13	chr16	89628801	T	C	single_nucleotide_variant	Pathogenic	Spondyloepimetaphyseal_dysplasia\|Spondyloepimetaphyseal_dysplasia,_Isidor-Toutain_type	SO:0001575\|splice_donor_variant	SO:0001575\|splice_donor_variant
RPL13	chr16	89629347	C	A	single_nucleotide_variant	Pathogenic	Spondyloepimetaphyseal_dysplasia,_Isidor-Toutain_type	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPL13	chr16	89629362	G	A	single_nucleotide_variant	Uncertain_significance	Spondyloepimetaphyseal_dysplasia,_Isidor-Toutain_type	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPL13	chr16	89629362	G	C	single_nucleotide_variant	Pathogenic	Spondyloepimetaphyseal_dysplasia,_Isidor-Toutain_type	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPL13	chr16	89629362	G	T	single_nucleotide_variant	Pathogenic	Spondyloepimetaphyseal_dysplasia	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPL13	chr16	89629367	G	C	single_nucleotide_variant	Pathogenic	Spondyloepimetaphyseal_dysplasia,_Isidor-Toutain_type	SO:0001583\|missense_variant	SO:0001583\|missense_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
RPL13	KIRP	chr16	89627425	89627425	C	T	Missense_Mutation	p.R20W	3
RPL13	SKCM	chr16	89628065	89628065	C	T	Missense_Mutation	p.S109F	2
RPL13	LIHC	chr16	89628073	89628073	G	A	Missense_Mutation		2
RPL13	UCEC	chr16	89628029	89628029	C	A	Missense_Mutation	p.S97Y	2
RPL13	BLCA	chr16	89629441	89629441	G	T	Missense_Mutation	p.K209N	2
RPL13	LIHC	chr16	89629361	89629361	C	T	Missense_Mutation	p.R183C	2
RPL13	LIHC	chr16	89629442	89629442	A	-	Frame_Shift_Del	p.K211fs	2
RPL13	ESCA	chr16	89629407	89629407	G	-	Frame_Shift_Del	p.R198fs	2
RPL13	SARC	chr16	89628056	89628056	C	A	Missense_Mutation		1
RPL13	BLCA	chr16	89628134	89628134	C	T	Missense_Mutation		1
RPL13	BLCA	chr16	89629387	89629387	C	G	Silent		1
RPL13	LIHC	chr16	89629361	89629361	C	T	Missense_Mutation		1
RPL13	STAD	chr16	89629397	89629397	C	G	Missense_Mutation	p.R195G	1
RPL13	BLCA	chr16	89628100	89628100	C	T	Missense_Mutation	p.R121C	1
RPL13	BLCA	chr16	89628134	89628134	C	T	Missense_Mutation	p.S132L	1
RPL13	LIHC	chr16	89628070	89628070	C	T	Nonsense_Mutation	p.Q111X	1
RPL13	BLCA	chr16	89629387	89629387	C	G	Silent	p.L191L	1
RPL13	LIHC	chr16	89628137	89628137	C	-	Frame_Shift_Del	p.A133fs	1
RPL13	COAD	chr16	89628037	89628037	C	A	Missense_Mutation	p.P100T	1
RPL13	LIHC	chr16	89629402	89629402	A	-	Frame_Shift_Del	p.A196fs	1
RPL13	DLBC	chr16	89629371	89629371	G	A	Missense_Mutation	p.R186H	1
RPL13	LUAD	chr16	89628078	89628078	C	T	Silent	p.N113N	1
RPL13	HNSC	chr16	89627382	89627382	G	C	Silent		1
RPL13	LUSC	chr16	89628749	89628749	G	A	Missense_Mutation	p.E143K	1
RPL13	BLCA	chr16	89628100	89628100	C	T	Missense_Mutation		1
RPL13	HNSC	chr16	89627382	89627382	G	C	Silent	p.R5R	1

Copy number variation (CNV) of RPL13
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across RPL13
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
82231	N/A	BM972522	AP000233.4	chr21	26703703	+	RPL13	chr16	89629846	-
82231	N/A	BE933378	CLPTM1	chr19	45494627	+	RPL13	chr16	89628766	+
82231	N/A	DA534037	DDX5	chr17	62500802	-	RPL13	chr16	89630778	+
82231	THCA	TCGA-DJ-A1QG	EGLN2	chr19	41307320	+	RPL13	chr16	89629291	+
82231	N/A	BE796741	ENTPD1	chr10	97485346	+	RPL13	chr16	89627137	+
82231	N/A	CR748210	MALAT1	chr11	65268002	+	RPL13	chr16	89629402	+
82231	N/A	AX381586	NRG3	chr10	84436537	+	RPL13	chr16	89627102	+
75938	N/A	AA534121	RPL13	chr16	89629848	+	C15orf53	chr15	39268621	-
100579	N/A	BF338090	RPL13	chr16	89629848	+	CD99	chrY	2588681	-
102228	N/A	EC503347	RPL13	chr16	89629401	-	CFL1	chr11	65622596	-
95562	N/A	AI540927	RPL13	chr16	89629485	+	CHODL	chr21	19543536	-
101372	N/A	EC567804	RPL13	chr16	89627416	+	GALNTL6	chr4	173722742	+
92696	N/A	EC564184	RPL13	chr16	89628019	-	GPR160	chr3	169763240	-
102796	PRAD	TCGA-EJ-A65M	RPL13	chr16	89629488	+	KLK3	chr19	51363681	+
94559	N/A	AA541370	RPL13	chr16	89629481	+	LRRIQ1	chr12	85496720	+
75938	N/A	AA524181	RPL13	chr16	89629431	-	MAPKAPK3	chr3	50683209	-
103124	LAML	TCGA-AB-2879-03A	RPL13	chr16	89629841	+	MPO	chr17	56347365	-
103124	LAML	TCGA-AB-3007-03A	RPL13	chr16	89628079	+	MPO	chr17	56349220	-
101515	N/A	AV681534	RPL13	chr16	89629471	+	NCAM2	chr21	22624075	-
75938	UCEC	TCGA-B5-A1MX-01A	RPL13	chr16	89628116	+	PPIC	chr5	122372237	-
91215	N/A	DB270526	RPL13	chr16	89627908	+	PTRF	chr17	40575274	-
93025	N/A	BG331404	RPL13	chr16	89628148	+	SETBP1	chr18	42363626	-
102305	N/A	AA885545	RPL13	chr16	89629481	+	STX8	chr17	9190002	+
101595	N/A	EC563515	RPL13	chr16	89628160	+	TAF3	chr10	7875868	-
101790	N/A	AI540941	RPL13	chr16	89629483	+	TCF12	chr15	57381805	-
92660	N/A	DB231778	RPL13	chr16	89627753	+	TNFRSF21	chr6	47277287	-
75938	N/A	EC543185	RPL13	chr16	89629727	-	YBEY	chr21	47710377	+
82232	BLCA	TCGA-DK-A2I2-01A	SLC12A6	chr15	34628611	-	RPL13	chr16	89627986	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type	Translation factor	Coefficent	Hazard ratio	Wald test pval	Likelihool ratio pval	Logrank test pval	# samples
KIRC	RPL13	1.4273821260126	0.355842085417157	0.000787701906175876	0.00113434712323181	0.000859171683503766	604
KIRC	RPL13	1.4273821260126	0.355842085417157	0.000787701906175876	0.00113434712323181	0.000859171683503766	604
ACC	RPL13	1.82119581033042	0.599493323976403	0.0132499541781363	0.0116147261803273	0.0126408163897121	79
UVM	RPL13	0.465870445476483	-0.76384769750851	0.0216760575254249	0.0200346204887102	0.0199713868586446	80
LGG	RPL13	0.743744312549388	-0.296057969143956	0.0250737846690407	0.0239463819339522	0.025005085180214	525
BRCA	RPL13	0.813242510546672	-0.206725922958912	0.0324575379197398	0.0325586774002121	0.0326068327903475	1200

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRC	RPL13	0.0039426566010979	0.11
KIRP	RPL13	0.0043074644762796	0.12
SARC	RPL13	0.0167234509827324	0.43
ACC	RPL13	0.0405377727657521	1

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUSC	RPL13	0.00613554348232348	0.2
BRCA	RPL13	0.000525656559431002	0.017
PAAD	RPL13	0.0139271567722596	0.43

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C0024623	Malignant neoplasm of stomach	1	CTD_human
C1260899	Anemia, Diamond-Blackfan	1	GENOMICS_ENGLAND
C1708349	Hereditary Diffuse Gastric Cancer	1	CTD_human