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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: RPL34 (NCBI Gene ID:6164)

Gene Summary

Gene Summary

Gene Information	Gene Name: RPL34
	Gene ID: 6164
	Gene Symbol	RPL34
	Gene ID	6164
	Gene Name	ribosomal protein L34
	Synonyms	L34
	Cytomap	4q25
	Type of Gene	protein-coding
	Description	60S ribosomal protein L34large ribosomal subunit protein eL34leukemia-associated protein
	Modification date	20200313
	UniProtAcc	P49207

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0002181	Cytoplasmic translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
RPL34	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'RPL34[title] AND translation [title] AND human.'

Gene	Title	PMID
RPL34	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000506397	109542786	109542852	5UTR-5UTR
ENST00000394665	109543106	109543180	5CDS-5UTR
ENST00000394668	109543106	109543180	5CDS-5UTR
ENST00000502534	109543106	109543180	5CDS-5UTR
ENST00000394665	109543260	109543360	Frame-shift
ENST00000394667	109543260	109543360	Frame-shift
ENST00000394668	109543260	109543360	Frame-shift
ENST00000502534	109543260	109543360	Frame-shift
ENST00000506397	109543260	109543360	Frame-shift
ENST00000394665	109543670	109543774	Frame-shift
ENST00000394667	109543670	109543774	Frame-shift
ENST00000394668	109543670	109543774	Frame-shift
ENST00000502534	109543670	109543774	Frame-shift
ENST00000506397	109543670	109543774	Frame-shift
ENST00000394668	109546283	109546409	3UTR-3CDS

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
STAD	RPL34	1.945601737258	0.00471024587750435

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
TGCT	RPL34	-0.05892186	0.011857037
LUAD	RPL34	-0.090650628	0.025531875
KIRC	RPL34	-0.037976714	0.028968204
READ	RPL34	-0.041379376	0.040854185
CESC	RPL34	0.025814469	0.04761398

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with RPL34 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
DLBC	Cell metabolism gene	RPL34	TIMM9	0.811658982	2.59E-12
DLBC	Cell metabolism gene	RPL34	NME2	0.827918205	3.92E-13
DLBC	Cell metabolism gene	RPL34	SNRPD2	0.833989884	1.84E-13
DLBC	Cell metabolism gene	RPL34	FAU	0.836721281	1.29E-13
DLBC	Cell metabolism gene	RPL34	GFER	0.839481636	9.03E-14
DLBC	Cell metabolism gene	RPL34	PFDN5	0.84157354	6.84E-14
DLBC	CGC	RPL34	NACA	0.830188449	2.96E-13
DLBC	TF	RPL34	THAP4	0.803140191	6.50E-12
DLBC	TF	RPL34	NME2	0.827918205	3.92E-13
DLBC	TSG	RPL34	GNB2L1	0.869104672	1.16E-15
HNSC	Cell metabolism gene	RPL34	PFDN5	0.839098492	2.95E-151
KICH	Cell metabolism gene	RPL34	SNRPD2	0.823830025	1.16E-23
KICH	CGC	RPL34	NACA	0.801187065	1.49E-21
KICH	TSG	RPL34	GLTSCR2	0.812704935	1.37E-22
KIRP	Cell metabolism gene	RPL34	PFDN5	0.817856723	4.91E-79
KIRP	Cell metabolism gene	RPL34	FAU	0.855064043	1.43E-93
LGG	Cell metabolism gene	RPL34	FAU	0.813157831	3.36E-126
LGG	CGC	RPL34	NACA	0.813516165	2.13E-126
PCPG	CGC	RPL34	NACA	0.807945412	2.32E-44
PCPG	TSG	RPL34	GNB2L1	0.817861772	2.82E-46
PRAD	Cell metabolism gene	RPL34	PFDN5	0.810924579	1.22E-129
PRAD	Cell metabolism gene	RPL34	TOMM7	0.811499508	5.76E-130
PRAD	Cell metabolism gene	RPL34	TIMM9	0.812659423	1.26E-130
PRAD	Cell metabolism gene	RPL34	SNRPD2	0.847485093	7.49E-153
PRAD	Cell metabolism gene	RPL34	FAU	0.87394091	7.64E-174
PRAD	CGC	RPL34	NACA	0.857531359	2.55E-160
PRAD	Epifactor	RPL34	FBL	0.864427895	8.70E-166
PRAD	TSG	RPL34	GAS5	0.810037897	3.84E-129
PRAD	TSG	RPL34	GNB2L1	0.830355601	2.76E-141
THCA	Cell metabolism gene	RPL34	SNRPD2	0.831182529	1.98E-147
THCA	Cell metabolism gene	RPL34	PFDN5	0.852025464	2.38E-162
THCA	Cell metabolism gene	RPL34	FAU	0.865789886	1.59E-173
THYM	Cell metabolism gene	RPL34	ACOT8	0.803521643	8.33E-29
THYM	Cell metabolism gene	RPL34	APRT	0.80557316	4.74E-29
THYM	Cell metabolism gene	RPL34	PSMB1	0.807527024	2.75E-29
THYM	Cell metabolism gene	RPL34	LSM5	0.810406158	1.22E-29
THYM	Cell metabolism gene	RPL34	PSMC3	0.814983041	3.26E-30
THYM	Cell metabolism gene	RPL34	PSMB3	0.816372318	2.17E-30
THYM	Cell metabolism gene	RPL34	POLR2H	0.817087003	1.76E-30
THYM	Cell metabolism gene	RPL34	TIMM13	0.827126559	8.17E-32
THYM	Cell metabolism gene	RPL34	SNRPD3	0.829395729	3.97E-32
THYM	Cell metabolism gene	RPL34	PSMB7	0.838171425	2.20E-33
THYM	Cell metabolism gene	RPL34	PSMD13	0.841995185	5.92E-34
THYM	Cell metabolism gene	RPL34	LSM2	0.848539398	5.74E-35
THYM	Cell metabolism gene	RPL34	SMPD2	0.850752812	2.54E-35
THYM	Cell metabolism gene	RPL34	SSR2	0.853669779	8.53E-36
THYM	Cell metabolism gene	RPL34	SLC27A5	0.867718713	3.09E-38
THYM	Cell metabolism gene	RPL34	PFDN5	0.872181628	4.53E-39
THYM	Cell metabolism gene	RPL34	SNRPD2	0.874696156	1.49E-39
THYM	Cell metabolism gene	RPL34	TIMM8B	0.880447325	1.06E-40
THYM	Cell metabolism gene	RPL34	FAU	0.901269505	2.07E-45
THYM	Epifactor	RPL34	PPP4C	0.800355815	1.96E-28
THYM	Epifactor	RPL34	INO80E	0.802679477	1.05E-28
THYM	Epifactor	RPL34	ZNHIT1	0.812475044	6.76E-30
THYM	Epifactor	RPL34	SS18L2	0.817340109	1.63E-30
THYM	Epifactor	RPL34	SIRT6	0.820703251	5.95E-31
THYM	Epifactor	RPL34	BRMS1	0.852842764	1.17E-35
THYM	Epifactor	RPL34	FBL	0.856876114	2.49E-36
THYM	Epifactor	RPL34	TAF10	0.861001257	4.91E-37
THYM	IUPHAR	RPL34	MFSD2B	0.807469662	2.80E-29
THYM	IUPHAR	RPL34	PSMB1	0.807527024	2.75E-29
THYM	IUPHAR	RPL34	SIRT6	0.820703251	5.95E-31
THYM	IUPHAR	RPL34	SMPD2	0.850752812	2.54E-35
THYM	IUPHAR	RPL34	SLC27A5	0.867718713	3.09E-38
THYM	TF	RPL34	ZNF691	0.80081653	1.74E-28
THYM	TF	RPL34	ZNF787	0.800826591	1.73E-28
THYM	TF	RPL34	ZNF32	0.804629604	6.15E-29
THYM	TF	RPL34	THYN1	0.80485622	5.78E-29
THYM	TF	RPL34	ZNF444	0.805723101	4.55E-29
THYM	TF	RPL34	ZNF428	0.823229128	2.75E-31
THYM	TSG	RPL34	TSSC4	0.80589173	4.34E-29
THYM	TSG	RPL34	NPRL2	0.81346263	5.08E-30
THYM	TSG	RPL34	SIRT6	0.820703251	5.95E-31
THYM	TSG	RPL34	GLTSCR2	0.83888131	1.73E-33
THYM	TSG	RPL34	BRMS1	0.852842764	1.17E-35
THYM	TSG	RPL34	GNB2L1	0.879404975	1.73E-40
UCEC	Cell metabolism gene	RPL34	PFDN5	0.812261193	1.79E-48
UCS	Cell metabolism gene	RPL34	ACOT8	0.803521643	8.33E-29
UCS	Cell metabolism gene	RPL34	APRT	0.80557316	4.74E-29
UCS	Cell metabolism gene	RPL34	PSMB1	0.807527024	2.75E-29
UCS	Cell metabolism gene	RPL34	LSM5	0.810406158	1.22E-29
UCS	Cell metabolism gene	RPL34	PSMC3	0.814983041	3.26E-30
UCS	Cell metabolism gene	RPL34	PSMB3	0.816372318	2.17E-30
UCS	Cell metabolism gene	RPL34	POLR2H	0.817087003	1.76E-30
UCS	Cell metabolism gene	RPL34	TIMM13	0.827126559	8.17E-32
UCS	Cell metabolism gene	RPL34	SNRPD3	0.829395729	3.97E-32
UCS	Cell metabolism gene	RPL34	PSMB7	0.838171425	2.20E-33
UCS	Cell metabolism gene	RPL34	PSMD13	0.841995185	5.92E-34
UCS	Cell metabolism gene	RPL34	LSM2	0.848539398	5.74E-35
UCS	Cell metabolism gene	RPL34	SMPD2	0.850752812	2.54E-35
UCS	Cell metabolism gene	RPL34	SSR2	0.853669779	8.53E-36
UCS	Cell metabolism gene	RPL34	SLC27A5	0.867718713	3.09E-38
UCS	Cell metabolism gene	RPL34	PFDN5	0.872181628	4.53E-39
UCS	Cell metabolism gene	RPL34	SNRPD2	0.874696156	1.49E-39
UCS	Cell metabolism gene	RPL34	TIMM8B	0.880447325	1.06E-40
UCS	Cell metabolism gene	RPL34	FAU	0.901269505	2.07E-45
UCS	Epifactor	RPL34	PPP4C	0.800355815	1.96E-28
UCS	Epifactor	RPL34	INO80E	0.802679477	1.05E-28
UCS	Epifactor	RPL34	ZNHIT1	0.812475044	6.76E-30
UCS	Epifactor	RPL34	SS18L2	0.817340109	1.63E-30
UCS	Epifactor	RPL34	SIRT6	0.820703251	5.95E-31
UCS	Epifactor	RPL34	BRMS1	0.852842764	1.17E-35
UCS	Epifactor	RPL34	FBL	0.856876114	2.49E-36
UCS	Epifactor	RPL34	TAF10	0.861001257	4.91E-37
UCS	IUPHAR	RPL34	MFSD2B	0.807469662	2.80E-29
UCS	IUPHAR	RPL34	PSMB1	0.807527024	2.75E-29
UCS	IUPHAR	RPL34	SIRT6	0.820703251	5.95E-31
UCS	IUPHAR	RPL34	SMPD2	0.850752812	2.54E-35
UCS	IUPHAR	RPL34	SLC27A5	0.867718713	3.09E-38
UCS	TF	RPL34	ZNF691	0.80081653	1.74E-28
UCS	TF	RPL34	ZNF787	0.800826591	1.73E-28
UCS	TF	RPL34	ZNF32	0.804629604	6.15E-29
UCS	TF	RPL34	THYN1	0.80485622	5.78E-29
UCS	TF	RPL34	ZNF444	0.805723101	4.55E-29
UCS	TF	RPL34	ZNF428	0.823229128	2.75E-31
UCS	TSG	RPL34	TSSC4	0.80589173	4.34E-29
UCS	TSG	RPL34	NPRL2	0.81346263	5.08E-30
UCS	TSG	RPL34	SIRT6	0.820703251	5.95E-31
UCS	TSG	RPL34	GLTSCR2	0.83888131	1.73E-33
UCS	TSG	RPL34	BRMS1	0.852842764	1.17E-35
UCS	TSG	RPL34	GNB2L1	0.879404975	1.73E-40
UVM	TSG	RPL34	GAS5	0.840609141	1.81E-22

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
KIRP	RPL34	RPL18A	-1.51651392808885	0.00016188295558095
KICH	RPL34	RPS27A	1.75396693785956	0.000187873840332031
KIRP	RPL34	RPS16	-1.35957043617517	0.00019507110118866
COAD	RPL34	RPS3	1.48730375143014	0.000411599874496461
KIRP	RPL34	RPS11	-1.01861570565103	0.00105937570333481
LIHC	RPL34	RPL8	-4.84588284974558	0.00110314154326131
PRAD	RPL34	RPL18A	1.40600175748499	0.00205137828390396
KICH	RPL34	RPL19	1.36901182894089	0.00250792503356934
KICH	RPL34	RPS12	1.26997381758431	0.00308787822723389
LUAD	RPL34	RPL19	-1.31398026615725	0.00993159558412698
THCA	RPL34	RPS16	-6.16322798156577	0.0115764821363307
BLCA	RPL34	RPS12	-1.47804673440421	0.0204124450683594
BLCA	RPL34	RPS27A	-1.04747470069188	0.0258216857910156
HNSC	RPL34	RPS3	-4.73505819095135	0.0273726439852453
COAD	RPL34	RPS11	1.35307548998204	0.0312207043170929
LUSC	RPL34	RPL19	-2.14669889516666	0.044366810398747
KIRC	RPL34	RPL19	-2.73485271276676	1.33980982873695e-10
BRCA	RPL34	RPS12	-4.91239327478244	1.85340619742495e-09
KIRP	RPL34	RPL37	-1.17421621947139	2.26888805627823e-05
KIRC	RPL34	RPL35	-1.06475238059392	2.72286325678163e-08
KIRC	RPL34	RPL8	-1.18252459971773	5.64962994208288e-07
KIRP	RPL34	RPL8	-1.53003692350119	6.0301274061203e-05
KIRC	RPL34	RPS16	-1.66149869889384	7.8509870430991e-09
BRCA	RPL34	RPS27A	-4.28512148200424	7.8788217967112e-14
KIRC	RPL34	RPL37	-2.87198822058464	8.03913394748564e-12
KIRP	RPL34	RPL35	-1.52981101975496	9.0546440333128e-05
KIRC	RPL34	RPS3	-1.29560847926387	9.05905681935088e-10
KIRC	RPL34	RPL18A	-4.43079304960843	9.2516163152192e-11

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with RPL34

DDX56, CNBP, MAGEB2, EIF6, PSTPIP1, EBNA-LP, HDGF, CDK5, CDK4, CDK2, CUL1, CAND1, APP, UBL4A, PAN2, DAPK3, MAX, ZBTB1, MOV10, NXF1, BRCA1, RNF2, EBNA1BP2, RPL10A, RPL12, RPL13A, RPL14, RPL15, RPL21, RPL23, RPL23A, RPL24, RPL27, RPL27A, RPL28, RPL30, RPL32, RPL13, RPL18, RPL19, RPL22, RPL26, RPL26L1, RPL3, RPL31, RPL38, RPL6, RPL8, RPLP0, RPS13, RPS15A, RPS16, RPS20, RPL35, RPL35A, RPL36, RPL37A, RPL4, RPL5, RPL7, RPL7A, RPL9, RPLP1, RPS11, RPS14, RPS15, RPS18, RPS2, RPS21, RPS23, RPS25, LOC101929876, RPS26, RPS27, RPS3, RPS3A, RPS6, RPS8, RPS9, RPSA, UBA52, SFN, gag, SRPK2, KBTBD7, MCM2, ZNF746, CDH1, MTMR6, RRS1, CYLD, TRIM25, CFTR, MATN2, TRIP4, PYHIN1, LARP7, RNF31, TNF, MEPCE, AGR2, RECQL4, REST, MYC, Prkaa1, Prkab1, GRWD1, ATG16L1, PHB, USP14, NR2C2, PPP1CC, CTCF, VRK1, HIST1H4A, NOD2, SNRNP70, ITFG1, ARAF, STAU1, NFX1, WWP2, SOX2, EP300, PLEKHA4, NGB, PTEN, HCVgp1, ZC3H18, MAP3K14, PTPN6, RPS6KA2, NPM1, SNIP1, NEK4, DUX4, CIT, ANLN, AURKB, CHMP4C, ECT2, KIF14, KIF20A, KIF23, PRC1, NDN, Rnf183, BRD4, Apc2, RBM39, FBP1, DNAJB14, DNAJB8, DNAJC17, DNAJC19, DNAJC25, DNAJC5B, DNAJC8, SEC63, PARK2, UFL1, DDRGK1, COIL, MARCKS, POLR1E, POLR2C, PTK2, ATG10, WDR5, PAGE4, MAP4K5, MINK1, NAA40, KIAA0020, DES, RAB11B, ZNF320, C8orf33, NCOR2, RAB11FIP5, RAB11FIP1, PRKRA, BTF3, FBXW7, DDX21, Dusp14, NLRP7, RCHY1, CCNF, N, E2F1, ESR1, FOXQ1, GATA3, KLF9, MYB, TAL1,

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Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
RPL34	PAAD	chr4	109546294	109546294	G	A	Missense_Mutation	p.A94T	3
RPL34	UCS	chr4	109543322	109543322	A	C	Missense_Mutation	p.K43Q	3
RPL34	ESCA	chr4	109546356	109546356	G	C	Missense_Mutation	p.Q114H	3
RPL34	PAAD	chr4	109543139	109543139	A	T	Silent	p.R8R	3
RPL34	UCEC	chr4	109546291	109546291	C	T	Missense_Mutation	p.R93C	2
RPL34	PAAD	chr4	109546320	109546320	C	A	Silent		2
RPL34	PAAD	chr4	109546320	109546320	C	A	Silent	p.I102I	2
RPL34	SKCM	chr4	109546299	109546299	C	T	Silent	p.F95F	2
RPL34	STAD	chr4	109543723	109543723	A	G	Missense_Mutation	p.H73R	2
RPL34	BLCA	chr4	109543281	109543281	G	T	Missense_Mutation		1
RPL34	UCS	chr4	109543322	109543322	A	C	Missense_Mutation		1
RPL34	BLCA	chr4	109543138	109543138	G	A	Missense_Mutation	p.R8Q	1
RPL34	BLCA	chr4	109543281	109543281	G	T	Missense_Mutation	p.R29I	1
RPL34	ESCA	chr4	109546356	109546356	G	C	Missense_Mutation		1
RPL34	PCPG	chr4	109543293	109543293	T	G	Missense_Mutation		1
RPL34	KIRC	chr4	109543167	109543191	AACAAAACTAGGCTGTAAGTATTTC	-	In_Frame_Del	p.17_22del	1
RPL34	PCPG	chr4	109543293	109543293	T	G	Missense_Mutation	p.L33R	1
RPL34	KIRC	chr4	109543328	109543328	G	A	Missense_Mutation	p.A45T	1
RPL34	PRAD	chr4	109543161	109543161	G	A	Missense_Mutation	p.A16T	1
RPL34	LIHC	chr4	109543160	109543160	A	G	Silent		1
RPL34	LUAD	chr4	109543286	109543286	G	A	Missense_Mutation	p.V31I	1
RPL34	LUSC	chr4	109543360	109543360	G	T	Silent	p.G55_splice	1
RPL34	STAD	chr4	109546411	109546411	T	C	Splice_Site		1
RPL34	BLCA	chr4	109543138	109543138	G	A	Missense_Mutation		1
RPL34	PAAD	chr4	109546294	109546294	G	A	Missense_Mutation		1

Copy number variation (CNV) of RPL34
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Fusion gene breakpoints (product of the structural variants (SVs)) across RPL34
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
95633	ESCA	TCGA-L5-A4OF-01A	AFF4	chr5	132215369	-	RPL34	chr4	109541732	+
95633	KIRP	TCGA-P4-A5E6	CFI	chr4	110723070	-	RPL34	chr4	109543670	+
95633	N/A	AA737195	DPP10	chr2	115325623	-	RPL34	chr4	109546412	-
95633	N/A	BG030675	EEF1A1	chr6	74228188	-	RPL34	chr4	109541733	+
95633	N/A	BF697308	INS-IGF2	chr11	2153279	-	RPL34	chr4	109546339	+
95633	N/A	AW897799	KARS	chr16	75664353	-	RPL34	chr4	109550411	+
95633	ESCA	TCGA-VR-A8EO	LEF1	chr4	109010280	-	RPL34	chr4	109543106	+
95633	N/A	AA534263	PDE4D	chr5	58458953	+	RPL34	chr4	109546410	-
87123	N/A	BF216579	RPL34	chr4	109546352	+	ANAPC1	chr2	112432225	+
102085	N/A	BI859847	RPL34	chr4	109546412	+	APP	chr21	27382267	+
92175	N/A	BF245968	RPL34	chr4	109546373	+	C17orf51	chr17	21346041	-
84062	STAD	TCGA-BR-4267	RPL34	chr4	109543774	+	CYB5R1	chr1	202932855	-
82612	BRCA	TCGA-AO-A1KS-01A	RPL34	chr4	109543360	+	DHRS12	chr13	52342432	-
90489	N/A	BG231214	RPL34	chr4	109546412	+	DPP10	chr2	115325623	+
76549	N/A	BM015512	RPL34	chr4	109546412	+	KIAA1024L	chr5	129102328	+
101604	N/A	AI624448	RPL34	chr4	109546303	-	NEK7	chr1	198291019	-
94324	N/A	EC574741	RPL34	chr4	109543720	+	NOL9	chr1	6608156	+
101068	N/A	AU126976	RPL34	chr4	109543328	+	PCCB	chr3	135969191	+
95633	N/A	EC455409	RPL34	chr4	109546292	-	RPL34	chr4	109546343	+
95633	N/A	EC493887	RPL34	chr4	109543742	+	RPL34	chr4	109543273	+
95633	N/A	EC565507	RPL34	chr4	109546323	-	RPL34	chr4	109546346	+
76549	N/A	AI973052	RPL34	chr4	109543740	-	SEMG1	chr20	43838315	+
99892	N/A	BG059237	RPL34	chr4	109546412	+	SS18	chr18	23649470	+
76549	N/A	AA954224	RPL34	chr4	109543745	-	TPT1-AS1	chr13	45966030	-
99295	N/A	BF246409	RPL34	chr4	109546373	+	WIPF2	chr17	38420593	+
95633	N/A	BM810873	TP53INP2	chr20	33298208	+	RPL34	chr4	109543688	+
95640	N/A	AA177148	TXNRD1	chr12	104675202	+	RPL34	chr4	109546403	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRC	RPL34	0.00500860361857862	0.14
SARC	RPL34	0.0229913433875496	0.62
KIRP	RPL34	0.0293703648373935	0.76

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRP	RPL34	0.0487313616399042	1

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source