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Translation Factor: RPS3A (NCBI Gene ID:6189) |
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 Gene Summary |
| Gene Information | Gene Name: RPS3A | Gene ID: 6189 | Gene Symbol | RPS3A | Gene ID | 6189 |
| Gene Name | ribosomal protein S3A | |
| Synonyms | FTE1|MFTL|S3A | |
| Cytomap | 4q31.3 | |
| Type of Gene | protein-coding | |
| Description | 40S ribosomal protein S3afte-1small ribosomal subunit protein eS1v-fos transformation effector protein 1 | |
| Modification date | 20200320 | |
| UniProtAcc | P61247 | |
| Child GO biological process term(s) under GO:0006412 |
| GO ID | GO term |
| GO:0005840 | Ribosome |
| GO:0002181 | Cytoplasmic translation |
| GO:0006413 | Translational initiation |
| GO:0006412 | Translation |
| Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Inferred gene age of translation factor. |
| Gene | Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25 |
| RPS3A | >1119.25 |
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| We searched PubMed using 'RPS3A[title] AND translation [title] AND human.' |
| Gene | Title | PMID |
| RPS3A | . | . |
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| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. For more annotations, please visit our ExonSkipDB. |
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| Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ENST | Exon skip start (DNA) | Exon Skip end (DNA) | ORF |
| ENST00000274065 | 152022126 | 152022314 | Frame-shift |
| ENST00000274065 | 152024022 | 152024231 | Frame-shift |
| ENST00000274065 | 152025328 | 152025438 | Frame-shift |
| Exon skipping position in the amino acid sequence. |
| ENST | Exon skip start (DNA) | Exon Skip end (DNA) | Len(transcript seq) | Exon skip start (mRNA) | Exon Skip end (mRNA) | Len(amino acid seq) | Exon skip start (AA) | Exon Skip end (AA) |
| Potentially (partially) lost protein functional features of UniProt. |
| UniProtAcc | Exon skip start (AA) | Exon Skip end (AA) | Function feature start (AA) | Function feature end (AA) | Functional feature type | Functional feature desc. |
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| Gene expression level across TCGA pancancer |
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| Gene expression level across GTEx pantissue |
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| Expression level of gene isoforms across TCGA pancancer |
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| Expression level of gene isoforms across GTEx pantissue |
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| Cancer(tissue) type-specific expression level of Translation factor using z-score distriution |
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| Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples) |
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| Cancer type | Translation factor | FC | adj.pval |
| CHOL | RPS3A | -2.95593562926717 | 0.00390625 |
| UCEC | RPS3A | -1.59353225186968 | 0.03125 |
| BRCA | RPS3A | -2.82352324218764 | 1.9558540533629e-14 |
| STAD | RPS3A | 1.42181649915045 | 9.0546440333128e-05 |
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| Translation factor expression regulation through miRNA binding |
| Cancer type | Gene | miRNA | TargetScan binding score (Context++ score percentile) | Coefficient | Pvalue |
| Translation factor expression regulation through methylation in the promoter of Translation factor |
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| Cancer type | Gene | methyl group b | methyl group a | DEG pval | avg methyl in b | avg methyl in a | avg exp in b | avg exp in a |
| Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation) |
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| Cancer type | Gene | methyl group b | methyl group a | DEG pval | avg methyl in b | avg methyl in a | avg exp in b | avg exp in a |
| Translation factor expression regulation through copy number variation of Translation factor |
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| Cancer type | Gene | Coefficient | Pvalue |
| PRAD | RPS3A | 0.057058715 | 0.020857063 |
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| Strongly correlated genes belong to cellular important gene groups with RPS3A (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green) |
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| Cancer type | Gene group | Translation factor | Correlated gene | Coefficient | Pvalue |
| DLBC | Cell metabolism gene | RPS3A | GFER | 0.806005723 | 4.80E-12 |
| DLBC | Cell metabolism gene | RPS3A | NME2 | 0.80876139 | 3.56E-12 |
| DLBC | Cell metabolism gene | RPS3A | FAU | 0.813431442 | 2.13E-12 |
| DLBC | Cell metabolism gene | RPS3A | PFDN5 | 0.819257492 | 1.10E-12 |
| DLBC | Cell metabolism gene | RPS3A | SNRPD2 | 0.835257184 | 1.56E-13 |
| DLBC | CGC | RPS3A | NACA | 0.850388905 | 2.02E-14 |
| DLBC | TF | RPS3A | NME2 | 0.80876139 | 3.56E-12 |
| DLBC | TSG | RPS3A | GLTSCR2 | 0.82144436 | 8.51E-13 |
| DLBC | TSG | RPS3A | GNB2L1 | 0.921106104 | 1.80E-20 |
| GBM | Cell metabolism gene | RPS3A | LYPLA1 | 0.801344277 | 8.81E-40 |
| GBM | Cell metabolism gene | RPS3A | TIMM8B | 0.805753206 | 1.60E-40 |
| GBM | Cell metabolism gene | RPS3A | PSMB4 | 0.805855413 | 1.54E-40 |
| GBM | Cell metabolism gene | RPS3A | SUCLG1 | 0.807844521 | 7.02E-41 |
| GBM | Cell metabolism gene | RPS3A | ZNRD1 | 0.808022434 | 6.55E-41 |
| GBM | Cell metabolism gene | RPS3A | LSM2 | 0.820329538 | 4.11E-43 |
| GBM | Cell metabolism gene | RPS3A | PSMA5 | 0.822412613 | 1.68E-43 |
| GBM | Cell metabolism gene | RPS3A | SSR2 | 0.826902362 | 2.33E-44 |
| GBM | Cell metabolism gene | RPS3A | FAU | 0.827844319 | 1.53E-44 |
| GBM | Cell metabolism gene | RPS3A | SNRPG | 0.850998275 | 2.02E-49 |
| GBM | Cell metabolism gene | RPS3A | CCT4 | 0.851047748 | 1.97E-49 |
| GBM | Cell metabolism gene | RPS3A | SNRPD2 | 0.851360623 | 1.67E-49 |
| GBM | Cell metabolism gene | RPS3A | PFDN5 | 0.87643568 | 7.71E-56 |
| LAML | CGC | RPS3A | NACA | 0.855454731 | 9.65E-51 |
| LGG | CGC | RPS3A | NACA | 0.813317146 | 2.74E-126 |
| THYM | IUPHAR | RPS3A | MFSD2B | 0.811349509 | 9.33E-30 |
| THYM | TSG | RPS3A | GNB2L1 | 0.802530225 | 1.09E-28 |
| UCS | IUPHAR | RPS3A | MFSD2B | 0.811349509 | 9.33E-30 |
| UCS | TSG | RPS3A | GNB2L1 | 0.802530225 | 1.09E-28 |
| UVM | Cell metabolism gene | RPS3A | PMPCB | 0.813783767 | 4.54E-20 |
| UVM | Cell metabolism gene | RPS3A | GLCE | 0.814381045 | 4.05E-20 |
| UVM | Cell metabolism gene | RPS3A | TOMM20 | 0.820367442 | 1.27E-20 |
| UVM | Epifactor | RPS3A | MBIP | 0.808635537 | 1.18E-19 |
| UVM | Epifactor | RPS3A | DDX50 | 0.839284272 | 2.43E-22 |
| UVM | Epifactor | RPS3A | FAM175A | 0.869803078 | 1.21E-25 |
| UVM | TF | RPS3A | ZNF354A | 0.810080755 | 9.07E-20 |
| UVM | TF | RPS3A | ZNF561 | 0.81079352 | 7.95E-20 |
| UVM | TF | RPS3A | ZNF277 | 0.843452261 | 9.49E-23 |
| UVM | TSG | RPS3A | RBMX | 0.805079129 | 2.26E-19 |
| UVM | TSG | RPS3A | COPS2 | 0.808066799 | 1.31E-19 |
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| Protein 3D structure Visit iCn3D. |
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| Protein-protein interaction networks * Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P)) |
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| Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P)) |
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 * Edge colors based on TCGA cancer types. |
| * Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P)) |
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| Cancer type | Translation factor | Interacting protein coding gene | FC | adj.pval |
| KIRP | RPS3A | RPL18A | -1.51651392808885 | 0.00016188295558095 |
| KICH | RPS3A | RPS27A | 1.75396693785956 | 0.000187873840332031 |
| KIRP | RPS3A | RPS16 | -1.35957043617517 | 0.00019507110118866 |
| STAD | RPS3A | RPS23 | 1.85076760664576 | 0.000364991836249828 |
| COAD | RPS3A | RPS3 | 1.48730375143014 | 0.000411599874496461 |
| KIRP | RPS3A | RPS11 | -1.01861570565103 | 0.00105937570333481 |
| LIHC | RPS3A | RPL8 | -4.84588284974558 | 0.00110314154326131 |
| PRAD | RPS3A | RPL18A | 1.40600175748499 | 0.00205137828390396 |
| KICH | RPS3A | RPL19 | 1.36901182894089 | 0.00250792503356934 |
| KICH | RPS3A | RPS12 | 1.26997381758431 | 0.00308787822723389 |
| LUAD | RPS3A | RPL19 | -1.31398026615725 | 0.00993159558412698 |
| THCA | RPS3A | RPS16 | -6.16322798156577 | 0.0115764821363307 |
| LUSC | RPS3A | RPS23 | 1.46751169891047 | 0.0174932185880974 |
| BLCA | RPS3A | RPS12 | -1.47804673440421 | 0.0204124450683594 |
| BLCA | RPS3A | RPS27A | -1.04747470069188 | 0.0258216857910156 |
| HNSC | RPS3A | RPS3 | -4.73505819095135 | 0.0273726439852453 |
| COAD | RPS3A | RPS11 | 1.35307548998204 | 0.0312207043170929 |
| LUSC | RPS3A | RPL19 | -2.14669889516666 | 0.044366810398747 |
| UCEC | RPS3A | RPS23 | -2.03658159814007 | 0.046875 |
| KIRC | RPS3A | RPL19 | -2.73485271276676 | 1.33980982873695e-10 |
| BRCA | RPS3A | RPS12 | -4.91239327478244 | 1.85340619742495e-09 |
| KIRC | RPS3A | RPL35 | -1.06475238059392 | 2.72286325678163e-08 |
| KIRC | RPS3A | RPL8 | -1.18252459971773 | 5.64962994208288e-07 |
| KIRP | RPS3A | RPL8 | -1.53003692350119 | 6.0301274061203e-05 |
| KIRC | RPS3A | RPS16 | -1.66149869889384 | 7.8509870430991e-09 |
| BRCA | RPS3A | RPS27A | -4.28512148200424 | 7.8788217967112e-14 |
| KIRP | RPS3A | RPL35 | -1.52981101975496 | 9.0546440333128e-05 |
| KIRC | RPS3A | RPS3 | -1.29560847926387 | 9.05905681935088e-10 |
| KIRC | RPS3A | RPL18A | -4.43079304960843 | 9.2516163152192e-11 |
| Protein-protein interactors with this translation factor (BIOGRID-3.4.160) |
| PPI interactors with RPS3A |
| MAGEB2, ASF1B, DDX56, CNBP, EIF1B, PINX1, MPDU1, LYAR, FANCC, CHN1, C11orf49, EDEM2, SAP18, SOD2, TOE1, HSP90AA1, DDIT3, PARP1, HGS, SRRM2, HDAC5, STAU1, RICTOR, EBNA-LP, PCK1, VHL, RAD21, ARRB1, ARRB2, SIRT7, NFX1, CUL3, CUL5, CUL2, CDK2, CUL1, COPS5, DCUN1D1, CAND1, NEDD8, RPL10A, RPL21, RPL5, RPL6, RPL7A, RPL7, RPS3, RPS6, RPSA, RPL4, RPS4X, RPLP0, RPS9, RPL12, RPL13, RPL14, RPL15, RPL17, RPL18A, RPL18, RPL19, RPL24, RPL27A, RPL37A, RPL3, RPL8, RPL9, RPS11, RPS13, RPS15A, RPS16, RPS23, RPS24, RPS25, RPS26, RPS5, RPS8, RPL11, RPS2, RPS19, RPLP2, RPL31, RPL23A, RPS20, RPS12, RPLP1, RPL23, RPL22, RPL10, EEF2, RPS17, RPL30, RPS15, RPL27, RPS14, RPS10, RPL35, RPS21, RPS27A, RPL29, RPL32, NCL, EEF1A1, ILF3, SLC25A5, NOP58, HNRNPA1, NAP1L1, EIF3C, RPL10L, RPLP0P6, MAT2A, PPT2, RPS27L, PC, PRKCDBP, SLC25A4, ATP5B, MRPL23, RNPC3, PDRG1, NENF, ESR1, SMURF1, HSP90AB1, FN1, VCAM1, NOS2, UBL4A, ITGA4, PAN2, CD81, IGSF8, ICAM1, TARDBP, NEDD4, EIF3A, EIF3CL, EIF3E, LARP1, RPS27, RPS28, GNB2L1, RPL28, RPS18, RPS29, WIBG, RPS7, SND1, TSR1, rev, RPA3, RPA2, RPA1, AURKA, CEP250, CEP57, CEP76, NEDD1, TP53, TUBG1, TUBGCP4, VCP, HUWE1, CUL7, OBSL1, CCDC8, UBE2I, RNF2, HIST1H1A, NOL12, ZNF22, NIFK, THAP7, ZC3H3, PRR11, RBM4B, ZNF317, RPS6KB2, NTRK1, ABCE1, HNRNPU, RPL13A, RPL38, LOC101929876, DHX37, KRR1, PABPC1, PABPC4, RPL26, RPL34, RPL35A, RPL36, RPL39, SFN, CREB3, XPO1, AHSA1, KIF11, MAD2L1, NPM1, NOP56, CBX8, NOP9, Eif3a, Eif3e, Rpl35, Srp72, Rrbp1, GAN, MCM2, NF2, Ksr1, Mdm2, RC3H1, CRBN, RRS1, WDR46, ZC3HAV1, RBM34, SART3, H2AFX, PPAN, ZCRB1, KNOP1, ZNF324B, ZBTB48, E4F1, ZNF512, U2AF2, HIST1H1T, KIAA0020, BHLHA15, GLTSCR2, HIST1H1E, ZNF2, FGF8, GPATCH4, ZBTB38, CYLD, EIF2AK2, INO80B, TRIM25, BRCA1, LMNA, MTF1, FBXO7, TMPO, WDR77, HDAC4, PCBP1, PPIE, YAF2, API5, BMP4, CTNNB1, GSK3A, JUP, MAP2K3, MED12, MED9, TGFB1, UBE2M, PRPF8, EFTUD2, AAR2, PIH1D1, CHD3, CHD4, RIOK1, HEXIM1, MEPCE, LARP7, SNAI1, RECQL4, REST, ZFP36L2, MYC, CDK9, FBL, AURKAIP1, GRWD1, METTL14, EIF4B, RC3H2, ACTC1, PHB, TGFBR2, FAF1, NR2C2, UBQLN2, PPP1CC, CTCF, ATXN3, VRK1, VRK3, HIST1H4A, PSMD14, SNRNP70, ITFG1, ARAF, HMGB1, BIRC3, WWP2, BRD7, MATR3, SOX2, TRIM28, ARIH2, PINK1, YAP1, TFCP2, FANCD2, NGB, HCVgp1, ORF50, ZC3H18, TXN2, SPTBN1, HIST2H2BF, SNIP1, ANKRD55, nsp13, ORF8, LARP4B, USP10, DUX4, CIT, ANLN, AURKB, CHMP4B, CHMP4C, ECT2, KIF14, KIF20A, MAD2L2, KIF23, PRC1, FASN, LDLR, INS, NMRAL1, NDN, Rnf183, BRD4, CIC, N, Apc2, RBM39, FBP1, LGALS9, IFI16, RIN3, DNAJC2, DNAJC8, OGT, BAG5, SPOP, PARK2, UFL1, DDRGK1, ACTR1A, LRRC59, LYN, SERBP1, SSR1, TUBA1A, TUBA4A, TRIM37, ATG3, LINC01232, UBQLN1, FZR1, PAGE4, NUDCD2, NAA40, YBX2, RPL26L1, RRP8, PRKRA, HERC5, NEIL1, UPF1, RPF2, ZNF689, YBX1, GADD45GIP1, DDX27, GLE1, BMS1, FGF13, DDX31, RRP12, ZNF668, WHSC1, NPM3, ZNF770, RSL1D1, SRSF3, RPL7L1, STAU2, GNL2, NMNAT1, HIST1H2AG, SURF6, RBM19, DHX57, LARP1B, GTPBP4, DDX21, MRPL27, H2AFB2, SRSF6, MRPL52, CCDC86, REXO4, GLYR1, LLPH, AATF, H1FNT, FTSJ3, MRPL2, SRSF5, HIST1H1C, TTF1, IPO4, ZCCHC9, APOBEC3C, SRPK2, ZCCHC3, SMEK2, RBM28, NOC4L, OASL, H2AFB3, ADARB1, PURG, NOP2, HIST1H1B, PRR3, MRPL28, UTP23, CBX6, MAK16, ZKSCAN8, ABT1, RPSAP58, LTV1, RPS4Y2, NOP14, NSA2, NGDN, HIST1H2AM, YBX3, ZNF346, SREK1, NOL10, NAT10, C8orf33, LIN28A, SPRTN, BTF3, TRIM26, FBXW7, NLRP7, FGD5, RCHY1, CCNF, SIRT6, PSMD9, RB1CC1, KLF4, TLX1, ZEB1, |
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| Clinically associated variants from ClinVar. |
| Gene | Chr | Position | RefSeq | VarSeq | RefSeeq | VarType | Pathogenic | Disease | VarInfo |
| RPS3A | chr4 | 152021631 | A | T | single_nucleotide_variant | Benign | not_provided | SO:0001627|intron_variant | SO:0001627|intron_variant |
| nsSNVs with sample frequency (size of circle) from TCGA 33 cancers. |
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| SNVs and Indels |
| Gene | Cancer type | Chromosome | Start | End | RefSeeq | MutSeq | Mutation type | AAchange | # samples |
| RPS3A | GBM | chr4 | 152024138 | 152024138 | A | C | Missense_Mutation | 12 | |
| RPS3A | KIRC | chr4 | 152022142 | 152022142 | G | A | Missense_Mutation | p.G48D | 4 |
| RPS3A | LAML | chr4 | 152243488 | 152243488 | C | T | Missense_Mutation | p.H124Y | 2 |
| RPS3A | PCPG | chr4 | 152024138 | 152024138 | A | C | Missense_Mutation | p.Q157P | 2 |
| RPS3A | LIHC | chr4 | 152025347 | 152025347 | A | - | Frame_Shift_Del | p.G157fs | 2 |
| RPS3A | ESCA | chr4 | 152020849 | 152020849 | G | A | Silent | 2 | |
| RPS3A | ESCA | chr4 | 152020849 | 152020849 | G | A | Silent | p.K15K | 2 |
| RPS3A | UCEC | chr4 | 152022212 | 152022212 | C | A | Missense_Mutation | p.F84L | 2 |
| RPS3A | PAAD | chr4 | 152021718 | 152021718 | C | A | Silent | p.L48L | 2 |
| RPS3A | BLCA | chr4 | 152024203 | 152024203 | A | C | Missense_Mutation | p.N166H | 1 |
| RPS3A | LIHC | chr4 | 152021639 | 152021639 | T | C | Missense_Mutation | p.V22A | 1 |
| RPS3A | SKCM | chr4 | 152025418 | 152025418 | T | C | Missense_Mutation | p.L218P | 1 |
| RPS3A | CESC | chr4 | 152022192 | 152022192 | G | A | Missense_Mutation | 1 | |
| RPS3A | LIHC | chr4 | 152025347 | 152025347 | A | - | Frame_Shift_Del | p.G194fs | 1 |
| RPS3A | SKCM | chr4 | 152024151 | 152024151 | C | T | Silent | p.V148V | 1 |
| RPS3A | CESC | chr4 | 152022192 | 152022192 | G | A | Missense_Mutation | p.E78K | 1 |
| RPS3A | SKCM | chr4 | 152025418 | 152025418 | T | C | Missense_Mutation | p.L181P | 1 |
| RPS3A | ESCA | chr4 | 152020849 | 152020849 | G | A | Silent | p.K15 | 1 |
| RPS3A | LIHC | chr4 | 152025410 | 152025410 | A | - | Frame_Shift_Del | p.V178fs | 1 |
| RPS3A | STAD | chr4 | 152024153 | 152024153 | G | A | Missense_Mutation | p.R162H | 1 |
| RPS3A | LUAD | chr4 | 152022138 | 152022138 | G | T | Missense_Mutation | p.D47Y | 1 |
| RPS3A | STAD | chr4 | 152024210 | 152024210 | T | C | Missense_Mutation | p.L181S | 1 |
| RPS3A | LUAD | chr4 | 152025386 | 152025386 | C | T | Missense_Mutation | p.P205S | 1 |
| RPS3A | UCEC | chr4 | 152021688 | 152021688 | G | T | Missense_Mutation | p.M38I | 1 |
| RPS3A | MESO | chr4 | 152021724 | 152021724 | C | A | Silent | 1 | |
| RPS3A | OV | chr4 | 152024193 | 152024193 | G | A | Silent | p.E175 | 1 |
| RPS3A | KIRP | chr4 | 152021725 | 152021725 | A | C | Silent | p.R51R | 1 |
| RPS3A | PAAD | chr4 | 152021718 | 152021718 | C | A | Silent | 1 | |
| RPS3A | BLCA | chr4 | 152024203 | 152024203 | A | C | Missense_Mutation | 1 | |
| RPS3A | KIRP | chr4 | 152024120 | 152024120 | G | T | Missense_Mutation | 1 | |
| RPS3A | BLCA | chr4 | 152020882 | 152020882 | C | T | Missense_Mutation | 1 |
| Copy number variation (CNV) of RPS3A * Click on the image to open the original image in a new window. |
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| Fusion gene breakpoints (product of the structural variants (SVs)) across RPS3A * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion genes with this translation factor from FusionGDB2.0. |
| FusionGDB2 ID | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 77889 | N/A | AA747634 | JMY | chr5 | 78580355 | + | RPS3A | chr4 | 152025789 | - |
| 77889 | N/A | EC560486 | RNF103-CHMP3 | chr2 | 86916294 | - | RPS3A | chr4 | 152025785 | - |
| 77891 | N/A | AA523477 | RPS3A | chr4 | 152025767 | + | JMY | chr5 | 78580137 | - |
| 77891 | N/A | BG030635 | RPS3A | chr4 | 152025789 | + | JMY | chr5 | 78579927 | - |
| 77891 | N/A | AA533662 | RPS3A | chr4 | 152024066 | + | RPS3A | chr4 | 152024180 | - |
| 98645 | N/A | EC500159 | RPS3A | chr4 | 152025783 | + | SH3D19 | chr4 | 152025921 | + |
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| Kaplan-Meier plots with logrank tests of overall survival (OS) |
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| Cancer type | Translation factor | Coefficent | Hazard ratio | Wald test pval | Likelihool ratio pval | Logrank test pval | # samples |
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| Differential gene expression between female and male. (Wilcoxon test, pval<0.05) |
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| Cancer type | Translation factor | pval | adj.p |
| COAD | RPS3A | 0.0216617579858607 | 0.58 |
| KIRC | RPS3A | 5.98210196336778e-05 | 0.0017 |
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| Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05) |
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| Cancer type | Translation factor | pval | adj.p |
| LGG | RPS3A | 0.0138143325342951 | 0.43 |
| BRCA | RPS3A | 0.00380194052512163 | 0.13 |
| PRAD | RPS3A | 0.0496920513667582 | 1 |
| THYM | RPS3A | 0.00476178988755091 | 0.15 |
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| Drugs targeting genes involved in this translation factor. (DrugBank Version 5.1.8 2021-05-08) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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| Diseases associated with this translation factor. (DisGeNet 4.0) |
| Disease ID | Disease Name | # PubMeds | Disease source |
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