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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: RPS4Y1 (NCBI Gene ID:6192)

Gene Summary

Gene Summary

Gene Information	Gene Name: RPS4Y1
	Gene ID: 6192
	Gene Symbol	RPS4Y1
	Gene ID	6192
	Gene Name	ribosomal protein S4 Y-linked 1
	Synonyms	RPS4Y\|S4
	Cytomap	Yp11.2
	Type of Gene	protein-coding
	Description	40S ribosomal protein S4, Y isoform 140S ribosomal protein S4, Yribosomal protein S4, Y-linkedribosomal protein S4Ysmall ribosomal subunit protein eS4
	Modification date	20200313
	UniProtAcc	P22090

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene

Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25

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Translation Studies in PubMed

We searched PubMed using 'RPS4Y1[title] AND translation [title] AND human.'

Gene	Title	PMID
RPS4Y1	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000250784	2713686	2713784	Frame-shift
ENST00000250784	2722640	2722812	Frame-shift
ENST00000250784	2733128	2733286	Frame-shift

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type

Translation factor

adj.pval

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type

Gene

Coefficient

Pvalue

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with RPS4Y1 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
ACC	Epifactor	RPS4Y1	UTY	0.95870358	8.48E-44
ACC	Epifactor	RPS4Y1	KDM5D	0.978167337	2.68E-54
ACC	IUPHAR	RPS4Y1	PRKY	0.949974972	1.16E-40
ACC	IUPHAR	RPS4Y1	KDM5D	0.978167337	2.68E-54
ACC	Kinase	RPS4Y1	PRKY	0.949974972	1.16E-40
ACC	TF	RPS4Y1	ZFY	0.979914155	1.12E-55
BLCA	Epifactor	RPS4Y1	UTY	0.920029977	1.28E-174
BLCA	Epifactor	RPS4Y1	KDM5D	0.943218134	4.70E-205
BLCA	IUPHAR	RPS4Y1	PRKY	0.94064564	4.28E-201
BLCA	IUPHAR	RPS4Y1	KDM5D	0.943218134	4.70E-205
BLCA	Kinase	RPS4Y1	PRKY	0.94064564	4.28E-201
BLCA	TF	RPS4Y1	ZFY	0.960941464	1.13E-238
BRCA	Epifactor	RPS4Y1	UTY	0.892459526	0
BRCA	Epifactor	RPS4Y1	KDM5D	0.904468595	0
BRCA	IUPHAR	RPS4Y1	KDM5D	0.904468595	0
BRCA	TF	RPS4Y1	ZFY	0.808076241	9.59E-282
CESC	Epifactor	RPS4Y1	KDM5D	0.818027474	1.76E-75
CESC	IUPHAR	RPS4Y1	KDM5D	0.818027474	1.76E-75
CHOL	Epifactor	RPS4Y1	KDM5D	0.988735109	4.16E-37
CHOL	Epifactor	RPS4Y1	UTY	0.992094475	2.12E-40
CHOL	IUPHAR	RPS4Y1	PRKY	0.948835574	3.78E-23
CHOL	IUPHAR	RPS4Y1	KDM5D	0.988735109	4.16E-37
CHOL	Kinase	RPS4Y1	PRKY	0.948835574	3.78E-23
CHOL	TF	RPS4Y1	ZFY	0.9803445	6.04E-32
COAD	Epifactor	RPS4Y1	UTY	0.946827506	4.20E-163
COAD	Epifactor	RPS4Y1	KDM5D	0.960216951	3.19E-183
COAD	IUPHAR	RPS4Y1	PRKY	0.920648324	1.26E-135
COAD	IUPHAR	RPS4Y1	KDM5D	0.960216951	3.19E-183
COAD	Kinase	RPS4Y1	PRKY	0.920648324	1.26E-135
COAD	TF	RPS4Y1	ZFY	0.958951761	4.81E-181
DLBC	Epifactor	RPS4Y1	UTY	0.957610899	1.67E-26
DLBC	Epifactor	RPS4Y1	KDM5D	0.966057514	1.10E-28
DLBC	IUPHAR	RPS4Y1	PRKY	0.931646381	7.47E-22
DLBC	IUPHAR	RPS4Y1	KDM5D	0.966057514	1.10E-28
DLBC	Kinase	RPS4Y1	PRKY	0.931646381	7.47E-22
DLBC	TF	RPS4Y1	ZFY	0.947819805	1.79E-24
ESCA	Epifactor	RPS4Y1	UTY	0.919118805	2.07E-80
ESCA	Epifactor	RPS4Y1	KDM5D	0.937059937	1.36E-90
ESCA	IUPHAR	RPS4Y1	KDM5D	0.937059937	1.36E-90
ESCA	IUPHAR	RPS4Y1	PRKY	0.938437697	1.70E-91
ESCA	Kinase	RPS4Y1	PRKY	0.938437697	1.70E-91
ESCA	TF	RPS4Y1	ZFY	0.981124199	2.13E-140
GBM	Epifactor	RPS4Y1	KDM5D	0.968073136	4.43E-104
GBM	Epifactor	RPS4Y1	UTY	0.977845075	2.17E-117
GBM	IUPHAR	RPS4Y1	PRKY	0.881010531	3.82E-57
GBM	IUPHAR	RPS4Y1	KDM5D	0.968073136	4.43E-104
GBM	Kinase	RPS4Y1	PRKY	0.881010531	3.82E-57
GBM	TF	RPS4Y1	ZFY	0.978607088	1.15E-118
HNSC	Epifactor	RPS4Y1	UTY	0.919207342	1.91E-230
HNSC	Epifactor	RPS4Y1	KDM5D	0.936159445	3.23E-258
HNSC	IUPHAR	RPS4Y1	PRKY	0.903447482	1.27E-209
HNSC	IUPHAR	RPS4Y1	KDM5D	0.936159445	3.23E-258
HNSC	Kinase	RPS4Y1	PRKY	0.903447482	1.27E-209
HNSC	TF	RPS4Y1	ZFY	0.942481198	1.36E-270
KICH	Epifactor	RPS4Y1	UTY	0.981593908	8.75E-66
KICH	Epifactor	RPS4Y1	KDM5D	0.991885644	1.62E-81
KICH	IUPHAR	RPS4Y1	PRKY	0.920499022	4.36E-38
KICH	IUPHAR	RPS4Y1	KDM5D	0.991885644	1.62E-81
KICH	Kinase	RPS4Y1	PRKY	0.920499022	4.36E-38
KICH	TF	RPS4Y1	ZFY	0.983152516	1.76E-67
KIRP	Epifactor	RPS4Y1	UTY	0.94849484	2.63E-162
KIRP	Epifactor	RPS4Y1	KDM5D	0.971972062	6.77E-204
KIRP	IUPHAR	RPS4Y1	PRKY	0.859041401	2.31E-95
KIRP	IUPHAR	RPS4Y1	KDM5D	0.971972062	6.77E-204
KIRP	Kinase	RPS4Y1	PRKY	0.859041401	2.31E-95
KIRP	TF	RPS4Y1	ZFY	0.946204091	2.36E-159
LAML	Epifactor	RPS4Y1	KDM5D	0.992755477	2.64E-159
LAML	Epifactor	RPS4Y1	UTY	0.994465101	2.87E-169
LAML	IUPHAR	RPS4Y1	PRKY	0.978509806	3.45E-119
LAML	IUPHAR	RPS4Y1	KDM5D	0.992755477	2.64E-159
LAML	Kinase	RPS4Y1	PRKY	0.978509806	3.45E-119
LAML	TF	RPS4Y1	ZFY	0.992085729	4.93E-156
LGG	Epifactor	RPS4Y1	UTY	0.986439418	0
LGG	Epifactor	RPS4Y1	KDM5D	0.987902206	0
LGG	IUPHAR	RPS4Y1	PRKY	0.943294122	4.98E-255
LGG	IUPHAR	RPS4Y1	KDM5D	0.987902206	0
LGG	Kinase	RPS4Y1	PRKY	0.943294122	4.98E-255
LGG	TF	RPS4Y1	ZFY	0.985696038	0
LIHC	Epifactor	RPS4Y1	KDM5D	0.954006535	2.23E-222
LIHC	Epifactor	RPS4Y1	UTY	0.955371645	4.53E-225
LIHC	IUPHAR	RPS4Y1	PRKY	0.9182729	1.71E-171
LIHC	IUPHAR	RPS4Y1	KDM5D	0.954006535	2.23E-222
LIHC	Kinase	RPS4Y1	PRKY	0.9182729	1.71E-171
LIHC	TF	RPS4Y1	ZFY	0.941813489	1.90E-201
LUAD	Epifactor	RPS4Y1	KDM5D	0.979114671	0
LUAD	Epifactor	RPS4Y1	UTY	0.980233509	0
LUAD	IUPHAR	RPS4Y1	PRKY	0.943272764	4.95E-277
LUAD	IUPHAR	RPS4Y1	KDM5D	0.979114671	0
LUAD	Kinase	RPS4Y1	PRKY	0.943272764	4.95E-277
LUAD	TF	RPS4Y1	ZFY	0.984765895	0
LUSC	Epifactor	RPS4Y1	UTY	0.948865211	4.37E-278
LUSC	Epifactor	RPS4Y1	KDM5D	0.955308672	8.27E-294
LUSC	IUPHAR	RPS4Y1	PRKY	0.887181364	3.17E-187
LUSC	IUPHAR	RPS4Y1	KDM5D	0.955308672	8.27E-294
LUSC	Kinase	RPS4Y1	PRKY	0.887181364	3.17E-187
LUSC	TF	RPS4Y1	ZFY	0.96660787	0
MESO	Epifactor	RPS4Y1	UTY	0.952595684	1.07E-45
MESO	Epifactor	RPS4Y1	KDM5D	0.985629094	1.98E-67
MESO	IUPHAR	RPS4Y1	PRKY	0.955296709	9.36E-47
MESO	IUPHAR	RPS4Y1	KDM5D	0.985629094	1.98E-67
MESO	Kinase	RPS4Y1	PRKY	0.955296709	9.36E-47
MESO	TF	RPS4Y1	ZFY	0.973998049	1.37E-56
PAAD	Epifactor	RPS4Y1	UTY	0.980408208	1.17E-129
PAAD	Epifactor	RPS4Y1	KDM5D	0.983431617	3.47E-136
PAAD	IUPHAR	RPS4Y1	PRKY	0.943662174	7.33E-89
PAAD	IUPHAR	RPS4Y1	KDM5D	0.983431617	3.47E-136
PAAD	Kinase	RPS4Y1	PRKY	0.943662174	7.33E-89
PAAD	TF	RPS4Y1	ZFY	0.968385785	4.39E-111
PCPG	Epifactor	RPS4Y1	UTY	0.979093203	6.71E-130
PCPG	Epifactor	RPS4Y1	KDM5D	0.983286449	8.26E-139
PCPG	IUPHAR	RPS4Y1	PRKY	0.947052872	3.27E-93
PCPG	IUPHAR	RPS4Y1	KDM5D	0.983286449	8.26E-139
PCPG	Kinase	RPS4Y1	PRKY	0.947052872	3.27E-93
PCPG	TF	RPS4Y1	ZFY	0.98173676	2.81E-135
READ	Epifactor	RPS4Y1	UTY	0.963147563	1.48E-60
READ	Epifactor	RPS4Y1	KDM5D	0.974159743	2.24E-68
READ	IUPHAR	RPS4Y1	PRKY	0.939356866	1.12E-49
READ	IUPHAR	RPS4Y1	KDM5D	0.974159743	2.24E-68
READ	Kinase	RPS4Y1	PRKY	0.939356866	1.12E-49
READ	TF	RPS4Y1	ZFY	0.977623599	1.48E-71
SKCM	Epifactor	RPS4Y1	UTY	0.952423273	1.06E-245
SKCM	Epifactor	RPS4Y1	KDM5D	0.968170566	4.42E-286
SKCM	IUPHAR	RPS4Y1	PRKY	0.932697934	3.50E-211
SKCM	IUPHAR	RPS4Y1	KDM5D	0.968170566	4.42E-286
SKCM	Kinase	RPS4Y1	PRKY	0.932697934	3.50E-211
SKCM	TF	RPS4Y1	ZFY	0.956690922	4.13E-255
STAD	Epifactor	RPS4Y1	UTY	0.961631149	8.92E-254
STAD	Epifactor	RPS4Y1	KDM5D	0.969537166	7.79E-276
STAD	IUPHAR	RPS4Y1	PRKY	0.951920166	2.63E-232
STAD	IUPHAR	RPS4Y1	KDM5D	0.969537166	7.79E-276
STAD	Kinase	RPS4Y1	PRKY	0.951920166	2.63E-232
STAD	TF	RPS4Y1	ZFY	0.978079031	1.98E-307
THCA	Epifactor	RPS4Y1	UTY	0.987206677	0
THCA	Epifactor	RPS4Y1	KDM5D	0.989562281	0
THCA	IUPHAR	RPS4Y1	PRKY	0.864457279	2.17E-172
THCA	IUPHAR	RPS4Y1	KDM5D	0.989562281	0
THCA	Kinase	RPS4Y1	PRKY	0.864457279	2.17E-172
THCA	TF	RPS4Y1	ZFY	0.984137149	0
THYM	Epifactor	RPS4Y1	KDM5D	0.984998373	2.00E-93
THYM	Epifactor	RPS4Y1	UTY	0.987489192	4.00E-98
THYM	IUPHAR	RPS4Y1	PRKY	0.954216189	9.61E-65
THYM	IUPHAR	RPS4Y1	KDM5D	0.984998373	2.00E-93
THYM	Kinase	RPS4Y1	PRKY	0.954216189	9.61E-65
THYM	TF	RPS4Y1	SRY	0.845625299	1.64E-34
THYM	TF	RPS4Y1	ZFY	0.963399862	1.85E-70
UCS	Epifactor	RPS4Y1	KDM5D	0.984998373	2.00E-93
UCS	Epifactor	RPS4Y1	UTY	0.987489192	4.00E-98
UCS	IUPHAR	RPS4Y1	PRKY	0.954216189	9.61E-65
UCS	IUPHAR	RPS4Y1	KDM5D	0.984998373	2.00E-93
UCS	Kinase	RPS4Y1	PRKY	0.954216189	9.61E-65
UCS	TF	RPS4Y1	SRY	0.845625299	1.64E-34
UCS	TF	RPS4Y1	ZFY	0.963399862	1.85E-70
UVM	Epifactor	RPS4Y1	UTY	0.960951572	2.82E-45
UVM	Epifactor	RPS4Y1	KDM5D	0.978842571	1.65E-55
UVM	IUPHAR	RPS4Y1	PRKY	0.880836042	4.76E-27
UVM	IUPHAR	RPS4Y1	KDM5D	0.978842571	1.65E-55
UVM	Kinase	RPS4Y1	PRKY	0.880836042	4.76E-27
UVM	TF	RPS4Y1	ZFY	0.918779571	3.20E-33

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type

Translation factor

Interacting protein coding gene

adj.pval

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with RPS4Y1

CALM1, CD81, IGSF8, ICAM1, RNF2, RPS4Y2, PRPS1, CLK1, ZNF746, CYLD, FGF11, ESR2, HEXIM1, MEPCE, LARP7, NR2C2, MEOX2, PLEKHA4, SNIP1, M, nsp13, nsp4, nsp5, nsp6, CIT, ANLN, AURKB, CHMP4B, CHMP4C, ECT2, KIF14, KIF20A, KIF23, PRC1, CBX8, WHSC1L1, AR, ACTR3B, ACOT7, PHYHIPL, CA5B, CCT3, RBKS, NCAPD3, PADI4, C1orf123, NEU2, TMCC2, RPL10A, AGPAT1, HSPBP1, RPS15, ACTR3, ZZEF1, AK3, SSSCA1, PINK1, WRAP53, SLURP1, RPS19, WDR37, SDC3, RPSAP58, FTL, YTHDF1, UGT3A1, HINT3, RPS8, LTV1, ZC3H10, SHMT2, CD55, ALDOA, RPL23A, NEUROG3, HECTD3, SPRTN,

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Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene

Cancer type

Chromosome

Start

End

RefSeeq

MutSeq

Mutation type

AAchange

# samples

Copy number variation (CNV) of RPS4Y1
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across RPS4Y1
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
103203	N/A	BF340665	ACADVL	chr17	7128585	+	RPS4Y1	chrY	2758841	+
103203	N/A	BD237243	ADIRF	chr10	88730488	+	RPS4Y1	chrY	2758842	+
103203	N/A	AF116711	ALB	chr4	74281996	-	RPS4Y1	chrY	2709643	+
103203	N/A	AA525486	CABLES1	chr18	20808709	-	RPS4Y1	chrY	2734997	-
103203	PAAD	TCGA-F2-A7TX	DHRSX	chrX	2209543	-	RPS4Y1	chrY	2733129	+
103203	PAAD	TCGA-F2-A7TX	DHRSX	chrY	2159542	-	RPS4Y1	chrY	2733128	+
103203	PAAD	TCGA-F2-A7TX-01A	DHRSX	chrY	2159543	-	RPS4Y1	chrY	2733129	+
103203	N/A	EI796321	FCHSD2	chr11	72808161	-	RPS4Y1	chrY	2610246	+
103203	N/A	AI147734	PIWIL1	chr12	130893959	+	RPS4Y1	chrY	2752404	-
103203	N/A	AW300778	RPS19	chr19	42364325	-	RPS4Y1	chrY	2734859	+
100335	N/A	BI047537	RPS4Y1	chrY	2733176	+	ARGLU1	chr13	107220075	+
97159	GBM	TCGA-06-0132-01A	RPS4Y1	chrY	2712298	+	CDH13	chr16	83158990	+
100283	STAD	TCGA-RD-A7BT-01A	RPS4Y1	chrY	2713784	+	DHRSX	chrY	2260515	-
89814	N/A	EC580829	RPS4Y1	chrY	2753051	-	EIF3D	chr22	36906903	+
97936	N/A	CB054335	RPS4Y1	chrY	2758836	-	FNBP1	chr9	132654163	+
77951	N/A	BI495156	RPS4Y1	chrY	2734988	+	LINC00366	chr13	39146582	+
77951	N/A	BQ351516	RPS4Y1	chrY	2733263	+	MKNK2	chr19	2037878	+
103203	N/A	BF810102	RPS4Y1	chrY	2715654	+	RPS4Y1	chrY	2715518	-
103203	N/A	CB049280	SMAD2	chr18	45363929	-	RPS4Y1	chrY	2734988	-
103203	GBM	TCGA-06-0132-01A	SRCAP	chr16	30727800	+	RPS4Y1	chrY	2722641	+
103204	N/A	EC465045	ZRANB2-AS1	chr1	71515651	-	RPS4Y1	chrY	2734834	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
TGCT	RPS4Y1	0.0131500789148087	0.013
ESCA	RPS4Y1	1.07130202086949e-18	9.6e-18
LUSC	RPS4Y1	1.09390469832596e-71	2.4e-70
LIHC	RPS4Y1	1.15196170977466e-63	2.3e-62
THYM	RPS4Y1	1.65605361677016e-21	1.8e-20
COAD	RPS4Y1	1.67630067703086e-53	3e-52
KIRC	RPS4Y1	1.89633269722089e-87	5.1e-86
UVM	RPS4Y1	1.96021999823571e-14	1.2e-13
BRCA	RPS4Y1	2.1139827627896e-20	2.1e-19
BLCA	RPS4Y1	2.18748701281115e-56	4.2e-55
KIRP	RPS4Y1	2.33371114703326e-41	3.7e-40
LGG	RPS4Y1	2.47940778597488e-86	6.4e-85
LAML	RPS4Y1	2.50685696211605e-32	3.8e-31
STAD	RPS4Y1	2.53112267444388e-69	5.3e-68
ACC	RPS4Y1	3.30149139032644e-14	1.7e-13
PCPG	RPS4Y1	3.34186924324147e-32	4.7e-31
DLBC	RPS4Y1	3.44060419479513e-09	1e-08
PAAD	RPS4Y1	3.56513630089674e-31	4.6e-30
READ	RPS4Y1	4.03524212666965e-18	3.2e-17
LUAD	RPS4Y1	4.25964790062367e-96	1.2e-94
HNSC	RPS4Y1	4.34722958285396e-73	1e-71
SARC	RPS4Y1	4.91567994863942e-45	8.4e-44
MESO	RPS4Y1	5.03758590774822e-10	2e-09
SKCM	RPS4Y1	5.83143851814514e-75	1.4e-73
KICH	RPS4Y1	6.85480567396137e-16	4.8e-15
THCA	RPS4Y1	6.98763656566539e-80	1.7e-78
GBM	RPS4Y1	7.20624186303352e-28	8.6e-27
CHOL	RPS4Y1	9.25673590399124e-09	1.9e-08

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
STAD	RPS4Y1	0.0183363485272767	0.57
KIRC	RPS4Y1	4.0499515858376e-05	0.0013
KICH	RPS4Y1	0.0193046005236163	0.58
CHOL	RPS4Y1	0.0233358849088145	0.68
HNSC	RPS4Y1	0.0130624619559932	0.42
READ	RPS4Y1	0.0257069804909004	0.72

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source