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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: RPS11 (NCBI Gene ID:6205)

Gene Summary

Gene Summary

Gene Information	Gene Name: RPS11
	Gene ID: 6205
	Gene Symbol	RPS11
	Gene ID	6205
	Gene Name	ribosomal protein S11
	Synonyms	S11
	Cytomap	19q13.33
	Type of Gene	protein-coding
	Description	40S ribosomal protein S11small ribosomal subunit protein uS17
	Modification date	20200327
	UniProtAcc	P62280

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0002181	Cytoplasmic translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene

Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25

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Translation Studies in PubMed

We searched PubMed using 'RPS11[title] AND translation [title] AND human.'

Gene	Title	PMID
RPS11	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000270625	50000450	50000582	In-frame
ENST00000270625	50000776	50000852	Frame-shift
ENST00000270625	50001173	50001303	Frame-shift

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000270625	50000450	50000582	631	99	230	158	5	49

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc	Exon skip start (AA)	Exon Skip end (AA)	Function feature start (AA)	Function feature end (AA)	Functional feature type	Functional feature desc.
P62280	5	49	2	158	Chain	ID=PRO_0000128509;Note=40S ribosomal protein S11
P62280	5	49	22	22	Modified residue	Note=Citrulline;Ontology_term=ECO:0000250;evidence=ECO:0000250
P62280	5	49	38	38	Modified residue	Note=N6-acetyllysine;Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:19608861;Dbxref=PMID:19608861
P62280	5	49	45	45	Modified residue	Note=N6-acetyllysine;Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:19608861;Dbxref=PMID:19608861

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
KIRP	RPS11	-1.01861570565103	0.00105937570333481
COAD	RPS11	1.35307548998204	0.0312207043170929

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
PRAD	RPS11	0.059513308	0.016250892
SARC	RPS11	-0.254058679	0.037233803
MESO	RPS11	0.056606789	0.038109664
GBM	RPS11	0.14756901	0.042449547

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with RPS11 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
ACC	Cell metabolism gene	RPS11	SNRPD2	0.803007273	5.52E-19
BLCA	TSG	RPS11	GLTSCR2	0.801808861	7.51E-97
CESC	Cell metabolism gene	RPS11	SNRPD2	0.812457774	1.12E-73
CESC	TSG	RPS11	GLTSCR2	0.845163745	3.06E-85
CHOL	Cell metabolism gene	RPS11	SNRPD2	0.825974331	2.86E-12
CHOL	TSG	RPS11	GLTSCR2	0.872532587	5.78E-15
COAD	Cell metabolism gene	RPS11	SNRPD2	0.80411309	7.59E-76
DLBC	Cell metabolism gene	RPS11	POLR2F	0.800993374	8.14E-12
DLBC	Cell metabolism gene	RPS11	TIMM9	0.808913628	3.50E-12
DLBC	Cell metabolism gene	RPS11	GEMIN7	0.811687404	2.58E-12
DLBC	Cell metabolism gene	RPS11	TIMM13	0.81212118	2.46E-12
DLBC	Cell metabolism gene	RPS11	GFER	0.812447499	2.38E-12
DLBC	Cell metabolism gene	RPS11	TOMM22	0.81595094	1.60E-12
DLBC	Cell metabolism gene	RPS11	TOMM7	0.816379725	1.53E-12
DLBC	Cell metabolism gene	RPS11	NME2	0.850167137	2.09E-14
DLBC	Cell metabolism gene	RPS11	PFDN5	0.885196929	6.77E-17
DLBC	Cell metabolism gene	RPS11	FAU	0.891943243	1.81E-17
DLBC	Cell metabolism gene	RPS11	SNRPD2	0.908749782	4.47E-19
DLBC	CGC	RPS11	NACA	0.869235971	1.13E-15
DLBC	Epifactor	RPS11	PRPF31	0.807902883	3.91E-12
DLBC	Epifactor	RPS11	FBL	0.870471903	9.22E-16
DLBC	TF	RPS11	THAP7	0.808195885	3.79E-12
DLBC	TF	RPS11	ZNF444	0.818866599	1.15E-12
DLBC	TF	RPS11	ZNF581	0.828993337	3.43E-13
DLBC	TF	RPS11	NME2	0.850167137	2.09E-14
DLBC	TSG	RPS11	GADD45GIP1	0.830331586	2.91E-13
DLBC	TSG	RPS11	GLTSCR2	0.871947097	7.20E-16
DLBC	TSG	RPS11	GNB2L1	0.900309227	3.12E-18
GBM	Cell metabolism gene	RPS11	SNRPG	0.801011292	1.00E-39
GBM	Cell metabolism gene	RPS11	SSR2	0.808059838	6.45E-41
GBM	Cell metabolism gene	RPS11	ZNRD1	0.817873747	1.17E-42
GBM	Cell metabolism gene	RPS11	GEMIN7	0.831268634	3.24E-45
GBM	Cell metabolism gene	RPS11	FAU	0.833645433	1.08E-45
GBM	Cell metabolism gene	RPS11	PFDN5	0.847946108	9.89E-49
GBM	Cell metabolism gene	RPS11	SNRPD2	0.900944835	1.56E-63
HNSC	Cell metabolism gene	RPS11	SNRPD2	0.807286742	2.79E-131
HNSC	Cell metabolism gene	RPS11	PFDN5	0.830896465	1.04E-145
KICH	Cell metabolism gene	RPS11	PFDN5	0.847890514	2.94E-26
KICH	Cell metabolism gene	RPS11	SNRPD2	0.866903668	1.19E-28
KICH	Epifactor	RPS11	PRMT1	0.809918005	2.48E-22
KICH	Epifactor	RPS11	FBL	0.816412366	6.14E-23
KICH	IUPHAR	RPS11	PRMT1	0.809918005	2.48E-22
KIRP	Cell metabolism gene	RPS11	PFDN5	0.803441219	2.84E-74
KIRP	Cell metabolism gene	RPS11	FAU	0.87439647	7.77E-103
KIRP	Cell metabolism gene	RPS11	SNRPD2	0.908455901	1.20E-123
KIRP	Epifactor	RPS11	FBL	0.879193848	2.25E-105
LGG	Epifactor	RPS11	FBL	0.874125562	1.00E-167
LGG	TF	RPS11	ZNF581	0.809716654	2.53E-124
LGG	TSG	RPS11	GLTSCR2	0.829949448	5.99E-136
LIHC	Cell metabolism gene	RPS11	PFDN5	0.801075292	7.06E-96
LIHC	Cell metabolism gene	RPS11	SNRPD2	0.82288658	2.09E-105
LIHC	Epifactor	RPS11	FBL	0.839486402	1.39E-113
LIHC	TSG	RPS11	GLTSCR2	0.807574431	1.37E-98
MESO	TSG	RPS11	GLTSCR2	0.894808957	1.64E-31
PAAD	Cell metabolism gene	RPS11	FAU	0.811200891	4.85E-44
PCPG	Cell metabolism gene	RPS11	PFDN5	0.850100746	2.06E-53
PCPG	Epifactor	RPS11	FBL	0.803148651	1.79E-43
PCPG	TSG	RPS11	GNB2L1	0.81472465	1.17E-45
PCPG	TSG	RPS11	GLTSCR2	0.88691894	5.82E-64
PRAD	Cell metabolism gene	RPS11	PFDN5	0.806276166	4.70E-127
PRAD	Cell metabolism gene	RPS11	POLR2F	0.808431875	3.03E-128
PRAD	Cell metabolism gene	RPS11	TOMM7	0.818211317	7.64E-134
PRAD	Cell metabolism gene	RPS11	PSMB7	0.820774408	2.29E-135
PRAD	Cell metabolism gene	RPS11	NME2	0.821722199	6.17E-136
PRAD	Cell metabolism gene	RPS11	ZNRD1	0.822676814	1.63E-136
PRAD	Cell metabolism gene	RPS11	POLR2I	0.825696649	2.31E-138
PRAD	Cell metabolism gene	RPS11	TIMM9	0.843964545	2.32E-150
PRAD	Cell metabolism gene	RPS11	SNRPD2	0.886942316	5.58E-186
PRAD	Cell metabolism gene	RPS11	FAU	0.887007034	4.81E-186
PRAD	CGC	RPS11	NACA	0.872706849	9.22E-173
PRAD	Epifactor	RPS11	FBL	0.903556333	7.38E-204
PRAD	TF	RPS11	ZNF524	0.807975785	5.43E-128
PRAD	TF	RPS11	ZNF581	0.811743541	4.19E-130
PRAD	TF	RPS11	NME2	0.821722199	6.17E-136
PRAD	TSG	RPS11	GAS5	0.802206586	7.59E-125
PRAD	TSG	RPS11	GNB2L1	0.893779345	5.63E-193
READ	Cell metabolism gene	RPS11	SNRPD2	0.846491541	5.86E-30
SKCM	TSG	RPS11	GLTSCR2	0.807177236	4.04E-110
THCA	Cell metabolism gene	RPS11	PFDN5	0.858883865	9.03E-168
THCA	Cell metabolism gene	RPS11	FAU	0.885325616	1.02E-191
THCA	Cell metabolism gene	RPS11	SNRPD2	0.901826458	7.09E-210
THCA	Epifactor	RPS11	FBL	0.860787949	2.51E-169
THCA	TSG	RPS11	GNB2L1	0.85020327	5.88E-161
THYM	Cell metabolism gene	RPS11	WBSCR22	0.800448905	1.92E-28
THYM	Cell metabolism gene	RPS11	SEC61G	0.80063352	1.82E-28
THYM	Cell metabolism gene	RPS11	LSM5	0.801188574	1.57E-28
THYM	Cell metabolism gene	RPS11	OAZ1	0.802153179	1.21E-28
THYM	Cell metabolism gene	RPS11	NANS	0.805736812	4.53E-29
THYM	Cell metabolism gene	RPS11	TOMM40	0.808831694	1.91E-29
THYM	Cell metabolism gene	RPS11	PFDN6	0.81017841	1.30E-29
THYM	Cell metabolism gene	RPS11	POLD4	0.810264983	1.27E-29
THYM	Cell metabolism gene	RPS11	GEMIN7	0.812026123	7.69E-30
THYM	Cell metabolism gene	RPS11	POLD2	0.814636925	3.61E-30
THYM	Cell metabolism gene	RPS11	PAFAH1B3	0.814786799	3.46E-30
THYM	Cell metabolism gene	RPS11	IDH3G	0.815957829	2.45E-30
THYM	Cell metabolism gene	RPS11	EXOSC1	0.816470419	2.11E-30
THYM	Cell metabolism gene	RPS11	TBCB	0.816701355	1.97E-30
THYM	Cell metabolism gene	RPS11	MTMR14	0.820376113	6.56E-31
THYM	Cell metabolism gene	RPS11	EXOSC4	0.825326473	1.44E-31
THYM	Cell metabolism gene	RPS11	DPM3	0.825409376	1.40E-31
THYM	Cell metabolism gene	RPS11	PSMB10	0.825499731	1.36E-31
THYM	Cell metabolism gene	RPS11	SRM	0.826284804	1.06E-31
THYM	Cell metabolism gene	RPS11	DGUOK	0.826850757	8.91E-32
THYM	Cell metabolism gene	RPS11	LSM4	0.827787126	6.63E-32
THYM	Cell metabolism gene	RPS11	PSME1	0.830971111	2.39E-32
THYM	Cell metabolism gene	RPS11	FPGS	0.831290359	2.16E-32
THYM	Cell metabolism gene	RPS11	EBP	0.831420093	2.07E-32
THYM	Cell metabolism gene	RPS11	MVD	0.834600334	7.29E-33
THYM	Cell metabolism gene	RPS11	PHKG2	0.836879763	3.41E-33
THYM	Cell metabolism gene	RPS11	UROD	0.8374429	2.82E-33
THYM	Cell metabolism gene	RPS11	GUK1	0.839822567	1.25E-33
THYM	Cell metabolism gene	RPS11	PSMB1	0.84031432	1.06E-33
THYM	Cell metabolism gene	RPS11	POLR2J	0.842835882	4.41E-34
THYM	Cell metabolism gene	RPS11	TOMM22	0.843420095	3.59E-34
THYM	Cell metabolism gene	RPS11	SNRPD3	0.850216717	3.10E-35
THYM	Cell metabolism gene	RPS11	DPM2	0.850852642	2.45E-35
THYM	Cell metabolism gene	RPS11	SMPD2	0.855776967	3.81E-36
THYM	Cell metabolism gene	RPS11	EXOSC5	0.855847786	3.71E-36
THYM	Cell metabolism gene	RPS11	POLR2H	0.857861269	1.70E-36
THYM	Cell metabolism gene	RPS11	ITPA	0.863808166	1.57E-37
THYM	Cell metabolism gene	RPS11	ACOT8	0.864080787	1.41E-37
THYM	Cell metabolism gene	RPS11	TIMM50	0.866352421	5.49E-38
THYM	Cell metabolism gene	RPS11	POLR2I	0.86731901	3.66E-38
THYM	Cell metabolism gene	RPS11	PSMC3	0.868437518	2.28E-38
THYM	Cell metabolism gene	RPS11	PSMD13	0.868935103	1.85E-38
THYM	Cell metabolism gene	RPS11	APRT	0.86951475	1.44E-38
THYM	Cell metabolism gene	RPS11	PSMB3	0.872024802	4.85E-39
THYM	Cell metabolism gene	RPS11	POLR2F	0.874051008	1.98E-39
THYM	Cell metabolism gene	RPS11	LSM2	0.876773183	5.81E-40
THYM	Cell metabolism gene	RPS11	PSMB7	0.878332389	2.84E-40
THYM	Cell metabolism gene	RPS11	TIMM13	0.879175181	1.92E-40
THYM	Cell metabolism gene	RPS11	SLC27A5	0.885638578	8.66E-42
THYM	Cell metabolism gene	RPS11	SSR2	0.889809035	1.06E-42
THYM	Cell metabolism gene	RPS11	PGLS	0.892756603	2.28E-43
THYM	Cell metabolism gene	RPS11	TIMM8B	0.898225773	1.17E-44
THYM	Cell metabolism gene	RPS11	PFDN5	0.911605978	3.72E-48
THYM	Cell metabolism gene	RPS11	SNRPD2	0.934695435	9.63E-56
THYM	Cell metabolism gene	RPS11	FAU	0.951607258	2.47E-63
THYM	CGC	RPS11	RBM10	0.846932638	1.03E-34
THYM	CGC	RPS11	SDHAF2	0.851969095	1.62E-35
THYM	CGC	RPS11	TFPT	0.878665076	2.44E-40
THYM	Epifactor	RPS11	RRP8	0.812459547	6.79E-30
THYM	Epifactor	RPS11	EXOSC1	0.816470419	2.11E-30
THYM	Epifactor	RPS11	PRMT1	0.816754825	1.94E-30
THYM	Epifactor	RPS11	PAF1	0.820304795	6.71E-31
THYM	Epifactor	RPS11	EXOSC4	0.825326473	1.44E-31
THYM	Epifactor	RPS11	CXXC1	0.826887254	8.81E-32
THYM	Epifactor	RPS11	MBD3	0.833256788	1.14E-32
THYM	Epifactor	RPS11	NOC2L	0.836535907	3.83E-33
THYM	Epifactor	RPS11	DMAP1	0.840346738	1.05E-33
THYM	Epifactor	RPS11	PPP4C	0.851373203	2.02E-35
THYM	Epifactor	RPS11	SS18L2	0.854758154	5.64E-36
THYM	Epifactor	RPS11	EXOSC5	0.855847786	3.71E-36
THYM	Epifactor	RPS11	PRPF31	0.864631751	1.12E-37
THYM	Epifactor	RPS11	C17orf49	0.86594645	6.51E-38
THYM	Epifactor	RPS11	CCDC101	0.868375797	2.34E-38
THYM	Epifactor	RPS11	INO80E	0.869822	1.26E-38
THYM	Epifactor	RPS11	ZNHIT1	0.872606596	3.76E-39
THYM	Epifactor	RPS11	RUVBL2	0.873018182	3.14E-39
THYM	Epifactor	RPS11	TFPT	0.878665076	2.44E-40
THYM	Epifactor	RPS11	SIRT6	0.888436399	2.13E-42
THYM	Epifactor	RPS11	BRMS1	0.893945648	1.21E-43
THYM	Epifactor	RPS11	FBL	0.913357019	1.18E-48
THYM	Epifactor	RPS11	TAF10	0.923351489	1.02E-51
THYM	IUPHAR	RPS11	EGLN2	0.811907991	7.95E-30
THYM	IUPHAR	RPS11	PRMT1	0.816754825	1.94E-30
THYM	IUPHAR	RPS11	MMP24	0.818870452	1.03E-30
THYM	IUPHAR	RPS11	PPIA	0.820243473	6.83E-31
THYM	IUPHAR	RPS11	CSNK2B	0.820401787	6.51E-31
THYM	IUPHAR	RPS11	MVD	0.834600334	7.29E-33
THYM	IUPHAR	RPS11	PHKG2	0.836879763	3.41E-33
THYM	IUPHAR	RPS11	PSMB1	0.84031432	1.06E-33
THYM	IUPHAR	RPS11	SMPD2	0.855776967	3.81E-36
THYM	IUPHAR	RPS11	SLC27A5	0.885638578	8.66E-42
THYM	IUPHAR	RPS11	SIRT6	0.888436399	2.13E-42
THYM	Kinase	RPS11	PHKG2	0.836879763	3.41E-33
THYM	TF	RPS11	USF1	0.805563457	4.75E-29
THYM	TF	RPS11	ZNF524	0.807244271	2.98E-29
THYM	TF	RPS11	ZNF668	0.807564727	2.72E-29
THYM	TF	RPS11	ZNF511	0.81142166	9.14E-30
THYM	TF	RPS11	ZNF691	0.819028902	9.85E-31
THYM	TF	RPS11	AKAP8L	0.822532087	3.41E-31
THYM	TF	RPS11	ETV2	0.825757515	1.26E-31
THYM	TF	RPS11	RBCK1	0.826472487	1.00E-31
THYM	TF	RPS11	CXXC1	0.826887254	8.81E-32
THYM	TF	RPS11	USF2	0.829472173	3.88E-32
THYM	TF	RPS11	IRF3	0.830161096	3.11E-32
THYM	TF	RPS11	MBD3	0.833256788	1.14E-32
THYM	TF	RPS11	ZNF581	0.838156679	2.21E-33
THYM	TF	RPS11	THAP7	0.840155942	1.12E-33
THYM	TF	RPS11	DRAP1	0.841335499	7.44E-34
THYM	TF	RPS11	ZNF444	0.847775411	7.58E-35
THYM	TF	RPS11	ZNF32	0.84893933	4.96E-35
THYM	TF	RPS11	ZNF688	0.859996149	7.33E-37
THYM	TF	RPS11	ZNF787	0.86350546	1.78E-37
THYM	TF	RPS11	THYN1	0.864600832	1.14E-37
THYM	TF	RPS11	THAP3	0.865993963	6.38E-38
THYM	TF	RPS11	ZNF428	0.88809661	2.54E-42
THYM	TSG	RPS11	ZNF668	0.807564727	2.72E-29
THYM	TSG	RPS11	PLEKHO1	0.815620024	2.71E-30
THYM	TSG	RPS11	IRF3	0.830161096	3.11E-32
THYM	TSG	RPS11	HTRA2	0.833566765	1.03E-32
THYM	TSG	RPS11	GABARAP	0.834499872	7.54E-33
THYM	TSG	RPS11	PFN1	0.837949095	2.38E-33
THYM	TSG	RPS11	AIP	0.855783885	3.80E-36
THYM	TSG	RPS11	NPRL2	0.870034592	1.15E-38
THYM	TSG	RPS11	GADD45GIP1	0.873727454	2.29E-39
THYM	TSG	RPS11	PARK7	0.876235917	7.42E-40
THYM	TSG	RPS11	TSSC4	0.876733662	5.92E-40
THYM	TSG	RPS11	SIRT6	0.888436399	2.13E-42
THYM	TSG	RPS11	BRMS1	0.893945648	1.21E-43
THYM	TSG	RPS11	GNB2L1	0.919949518	1.25E-50
THYM	TSG	RPS11	GLTSCR2	0.926012417	1.33E-52
UCEC	Cell metabolism gene	RPS11	FAU	0.800792286	3.52E-46
UCEC	Cell metabolism gene	RPS11	PFDN5	0.813189982	1.15E-48
UCS	Cell metabolism gene	RPS11	WBSCR22	0.800448905	1.92E-28
UCS	Cell metabolism gene	RPS11	SEC61G	0.80063352	1.82E-28
UCS	Cell metabolism gene	RPS11	LSM5	0.801188574	1.57E-28
UCS	Cell metabolism gene	RPS11	OAZ1	0.802153179	1.21E-28
UCS	Cell metabolism gene	RPS11	NANS	0.805736812	4.53E-29
UCS	Cell metabolism gene	RPS11	TOMM40	0.808831694	1.91E-29
UCS	Cell metabolism gene	RPS11	PFDN6	0.81017841	1.30E-29
UCS	Cell metabolism gene	RPS11	POLD4	0.810264983	1.27E-29
UCS	Cell metabolism gene	RPS11	GEMIN7	0.812026123	7.69E-30
UCS	Cell metabolism gene	RPS11	POLD2	0.814636925	3.61E-30
UCS	Cell metabolism gene	RPS11	PAFAH1B3	0.814786799	3.46E-30
UCS	Cell metabolism gene	RPS11	IDH3G	0.815957829	2.45E-30
UCS	Cell metabolism gene	RPS11	EXOSC1	0.816470419	2.11E-30
UCS	Cell metabolism gene	RPS11	TBCB	0.816701355	1.97E-30
UCS	Cell metabolism gene	RPS11	MTMR14	0.820376113	6.56E-31
UCS	Cell metabolism gene	RPS11	EXOSC4	0.825326473	1.44E-31
UCS	Cell metabolism gene	RPS11	DPM3	0.825409376	1.40E-31
UCS	Cell metabolism gene	RPS11	PSMB10	0.825499731	1.36E-31
UCS	Cell metabolism gene	RPS11	SRM	0.826284804	1.06E-31
UCS	Cell metabolism gene	RPS11	DGUOK	0.826850757	8.91E-32
UCS	Cell metabolism gene	RPS11	LSM4	0.827787126	6.63E-32
UCS	Cell metabolism gene	RPS11	PSME1	0.830971111	2.39E-32
UCS	Cell metabolism gene	RPS11	FPGS	0.831290359	2.16E-32
UCS	Cell metabolism gene	RPS11	EBP	0.831420093	2.07E-32
UCS	Cell metabolism gene	RPS11	MVD	0.834600334	7.29E-33
UCS	Cell metabolism gene	RPS11	PHKG2	0.836879763	3.41E-33
UCS	Cell metabolism gene	RPS11	UROD	0.8374429	2.82E-33
UCS	Cell metabolism gene	RPS11	GUK1	0.839822567	1.25E-33
UCS	Cell metabolism gene	RPS11	PSMB1	0.84031432	1.06E-33
UCS	Cell metabolism gene	RPS11	POLR2J	0.842835882	4.41E-34
UCS	Cell metabolism gene	RPS11	TOMM22	0.843420095	3.59E-34
UCS	Cell metabolism gene	RPS11	SNRPD3	0.850216717	3.10E-35
UCS	Cell metabolism gene	RPS11	DPM2	0.850852642	2.45E-35
UCS	Cell metabolism gene	RPS11	SMPD2	0.855776967	3.81E-36
UCS	Cell metabolism gene	RPS11	EXOSC5	0.855847786	3.71E-36
UCS	Cell metabolism gene	RPS11	POLR2H	0.857861269	1.70E-36
UCS	Cell metabolism gene	RPS11	ITPA	0.863808166	1.57E-37
UCS	Cell metabolism gene	RPS11	ACOT8	0.864080787	1.41E-37
UCS	Cell metabolism gene	RPS11	TIMM50	0.866352421	5.49E-38
UCS	Cell metabolism gene	RPS11	POLR2I	0.86731901	3.66E-38
UCS	Cell metabolism gene	RPS11	PSMC3	0.868437518	2.28E-38
UCS	Cell metabolism gene	RPS11	PSMD13	0.868935103	1.85E-38
UCS	Cell metabolism gene	RPS11	APRT	0.86951475	1.44E-38
UCS	Cell metabolism gene	RPS11	PSMB3	0.872024802	4.85E-39
UCS	Cell metabolism gene	RPS11	POLR2F	0.874051008	1.98E-39
UCS	Cell metabolism gene	RPS11	LSM2	0.876773183	5.81E-40
UCS	Cell metabolism gene	RPS11	PSMB7	0.878332389	2.84E-40
UCS	Cell metabolism gene	RPS11	TIMM13	0.879175181	1.92E-40
UCS	Cell metabolism gene	RPS11	SLC27A5	0.885638578	8.66E-42
UCS	Cell metabolism gene	RPS11	SSR2	0.889809035	1.06E-42
UCS	Cell metabolism gene	RPS11	PGLS	0.892756603	2.28E-43
UCS	Cell metabolism gene	RPS11	TIMM8B	0.898225773	1.17E-44
UCS	Cell metabolism gene	RPS11	PFDN5	0.911605978	3.72E-48
UCS	Cell metabolism gene	RPS11	SNRPD2	0.934695435	9.63E-56
UCS	Cell metabolism gene	RPS11	FAU	0.951607258	2.47E-63
UCS	CGC	RPS11	RBM10	0.846932638	1.03E-34
UCS	CGC	RPS11	SDHAF2	0.851969095	1.62E-35
UCS	CGC	RPS11	TFPT	0.878665076	2.44E-40
UCS	Epifactor	RPS11	RRP8	0.812459547	6.79E-30
UCS	Epifactor	RPS11	EXOSC1	0.816470419	2.11E-30
UCS	Epifactor	RPS11	PRMT1	0.816754825	1.94E-30
UCS	Epifactor	RPS11	PAF1	0.820304795	6.71E-31
UCS	Epifactor	RPS11	EXOSC4	0.825326473	1.44E-31
UCS	Epifactor	RPS11	CXXC1	0.826887254	8.81E-32
UCS	Epifactor	RPS11	MBD3	0.833256788	1.14E-32
UCS	Epifactor	RPS11	NOC2L	0.836535907	3.83E-33
UCS	Epifactor	RPS11	DMAP1	0.840346738	1.05E-33
UCS	Epifactor	RPS11	PPP4C	0.851373203	2.02E-35
UCS	Epifactor	RPS11	SS18L2	0.854758154	5.64E-36
UCS	Epifactor	RPS11	EXOSC5	0.855847786	3.71E-36
UCS	Epifactor	RPS11	PRPF31	0.864631751	1.12E-37
UCS	Epifactor	RPS11	C17orf49	0.86594645	6.51E-38
UCS	Epifactor	RPS11	CCDC101	0.868375797	2.34E-38
UCS	Epifactor	RPS11	INO80E	0.869822	1.26E-38
UCS	Epifactor	RPS11	ZNHIT1	0.872606596	3.76E-39
UCS	Epifactor	RPS11	RUVBL2	0.873018182	3.14E-39
UCS	Epifactor	RPS11	TFPT	0.878665076	2.44E-40
UCS	Epifactor	RPS11	SIRT6	0.888436399	2.13E-42
UCS	Epifactor	RPS11	BRMS1	0.893945648	1.21E-43
UCS	Epifactor	RPS11	FBL	0.913357019	1.18E-48
UCS	Epifactor	RPS11	TAF10	0.923351489	1.02E-51
UCS	IUPHAR	RPS11	EGLN2	0.811907991	7.95E-30
UCS	IUPHAR	RPS11	PRMT1	0.816754825	1.94E-30
UCS	IUPHAR	RPS11	MMP24	0.818870452	1.03E-30
UCS	IUPHAR	RPS11	PPIA	0.820243473	6.83E-31
UCS	IUPHAR	RPS11	CSNK2B	0.820401787	6.51E-31
UCS	IUPHAR	RPS11	MVD	0.834600334	7.29E-33
UCS	IUPHAR	RPS11	PHKG2	0.836879763	3.41E-33
UCS	IUPHAR	RPS11	PSMB1	0.84031432	1.06E-33
UCS	IUPHAR	RPS11	SMPD2	0.855776967	3.81E-36
UCS	IUPHAR	RPS11	SLC27A5	0.885638578	8.66E-42
UCS	IUPHAR	RPS11	SIRT6	0.888436399	2.13E-42
UCS	Kinase	RPS11	PHKG2	0.836879763	3.41E-33
UCS	TF	RPS11	USF1	0.805563457	4.75E-29
UCS	TF	RPS11	ZNF524	0.807244271	2.98E-29
UCS	TF	RPS11	ZNF668	0.807564727	2.72E-29
UCS	TF	RPS11	ZNF511	0.81142166	9.14E-30
UCS	TF	RPS11	ZNF691	0.819028902	9.85E-31
UCS	TF	RPS11	AKAP8L	0.822532087	3.41E-31
UCS	TF	RPS11	ETV2	0.825757515	1.26E-31
UCS	TF	RPS11	RBCK1	0.826472487	1.00E-31
UCS	TF	RPS11	CXXC1	0.826887254	8.81E-32
UCS	TF	RPS11	USF2	0.829472173	3.88E-32
UCS	TF	RPS11	IRF3	0.830161096	3.11E-32
UCS	TF	RPS11	MBD3	0.833256788	1.14E-32
UCS	TF	RPS11	ZNF581	0.838156679	2.21E-33
UCS	TF	RPS11	THAP7	0.840155942	1.12E-33
UCS	TF	RPS11	DRAP1	0.841335499	7.44E-34
UCS	TF	RPS11	ZNF444	0.847775411	7.58E-35
UCS	TF	RPS11	ZNF32	0.84893933	4.96E-35
UCS	TF	RPS11	ZNF688	0.859996149	7.33E-37
UCS	TF	RPS11	ZNF787	0.86350546	1.78E-37
UCS	TF	RPS11	THYN1	0.864600832	1.14E-37
UCS	TF	RPS11	THAP3	0.865993963	6.38E-38
UCS	TF	RPS11	ZNF428	0.88809661	2.54E-42
UCS	TSG	RPS11	ZNF668	0.807564727	2.72E-29
UCS	TSG	RPS11	PLEKHO1	0.815620024	2.71E-30
UCS	TSG	RPS11	IRF3	0.830161096	3.11E-32
UCS	TSG	RPS11	HTRA2	0.833566765	1.03E-32
UCS	TSG	RPS11	GABARAP	0.834499872	7.54E-33
UCS	TSG	RPS11	PFN1	0.837949095	2.38E-33
UCS	TSG	RPS11	AIP	0.855783885	3.80E-36
UCS	TSG	RPS11	NPRL2	0.870034592	1.15E-38
UCS	TSG	RPS11	GADD45GIP1	0.873727454	2.29E-39
UCS	TSG	RPS11	PARK7	0.876235917	7.42E-40
UCS	TSG	RPS11	TSSC4	0.876733662	5.92E-40
UCS	TSG	RPS11	SIRT6	0.888436399	2.13E-42
UCS	TSG	RPS11	BRMS1	0.893945648	1.21E-43
UCS	TSG	RPS11	GNB2L1	0.919949518	1.25E-50
UCS	TSG	RPS11	GLTSCR2	0.926012417	1.33E-52
UVM	Cell metabolism gene	RPS11	SSR2	0.899938415	7.59E-30
UVM	Cell metabolism gene	RPS11	FAU	0.919005773	2.88E-33
UVM	Epifactor	RPS11	FBL	0.920587506	1.38E-33
UVM	TF	RPS11	ZNF581	0.853031094	9.79E-24
UVM	TSG	RPS11	GNB2L1	0.866036798	3.42E-25
UVM	TSG	RPS11	GLTSCR2	0.883320491	2.20E-27

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
KIRP	RPS11	RPL18A	-1.51651392808885	0.00016188295558095
KICH	RPS11	RPS27A	1.75396693785956	0.000187873840332031
KIRP	RPS11	RPS16	-1.35957043617517	0.00019507110118866
STAD	RPS11	RPS23	1.85076760664576	0.000364991836249828
COAD	RPS11	RPS3	1.48730375143014	0.000411599874496461
LIHC	RPS11	RPL8	-4.84588284974558	0.00110314154326131
PRAD	RPS11	RPL18A	1.40600175748499	0.00205137828390396
KICH	RPS11	RPL19	1.36901182894089	0.00250792503356934
KICH	RPS11	RPS12	1.26997381758431	0.00308787822723389
LUAD	RPS11	RPL19	-1.31398026615725	0.00993159558412698
THCA	RPS11	RPS16	-6.16322798156577	0.0115764821363307
LUSC	RPS11	RPS23	1.46751169891047	0.0174932185880974
BLCA	RPS11	RPS12	-1.47804673440421	0.0204124450683594
BLCA	RPS11	RPS27A	-1.04747470069188	0.0258216857910156
HNSC	RPS11	RPS3	-4.73505819095135	0.0273726439852453
LUSC	RPS11	RPL19	-2.14669889516666	0.044366810398747
UCEC	RPS11	RPS23	-2.03658159814007	0.046875
KIRC	RPS11	RPL19	-2.73485271276676	1.33980982873695e-10
BRCA	RPS11	RPS12	-4.91239327478244	1.85340619742495e-09
KIRP	RPS11	RPL37	-1.17421621947139	2.26888805627823e-05
KIRC	RPS11	RPL35	-1.06475238059392	2.72286325678163e-08
KIRC	RPS11	RPL8	-1.18252459971773	5.64962994208288e-07
KIRP	RPS11	RPL8	-1.53003692350119	6.0301274061203e-05
KIRC	RPS11	RPS16	-1.66149869889384	7.8509870430991e-09
BRCA	RPS11	RPS27A	-4.28512148200424	7.8788217967112e-14
KIRC	RPS11	RPL37	-2.87198822058464	8.03913394748564e-12
KIRP	RPS11	RPL35	-1.52981101975496	9.0546440333128e-05
KIRC	RPS11	RPS3	-1.29560847926387	9.05905681935088e-10
KIRC	RPS11	RPL18A	-4.43079304960843	9.2516163152192e-11

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with RPS11

EIF1B, NDN, NELFCD, RUVBL2, DDX56, MAGEB2, UBC, HDAC5, EBNA-LP, VHL, RAD21, SENP3, HDGF, CUL3, CDK2, CUL1, COPS5, COPS6, CAND1, RPS4X, APP, RPL30, RPL4, RPS13, RPL6, RPL10A, RPL11, RPL12, RPL14, RPL15, RPL18A, RPL21, RPL24, RPL31, RPL37A, RPL5, RPLP2, RPS12, RPS14, RPS15A, RPS19, RPS23, RPS26, RPS3A, RPS3, RPS5, RPS8, RPS16, RPS2, RPL19, RPL23A, RPS7, RPL7, RPS24, RPL9, RPS6, RPL18, RPLP1, RPL7A, RPL22, RPL23, RPLP0, RPS10, RPL17, RPS21, RPS27A, FBL, EEF1A1, DDX21, TUFM, MYBBP1A, HNRNPU, NOP58, NOP56, HNRNPM, DHX9, NHP2L1, EIF4A3, RPLP0P6, RPL10L, NCSTN, RPS10P5, SF3B6, RPS27L, PRKDC, CDC5L, PRPF4B, LOC255308, PSIP1, VTN, DDX3X, NFIA, MAGOH, SMURF1, ESR2, FN1, VCAM1, UBL4A, ITGA4, PAN2, DUSP10, AGO2, TARDBP, EIF3CL, EIF3D, RPL35, RPS17, RPS20, SND1, RPS9, ZBTB1, AURKA, CEP250, CEP57, CEP76, TUBG1, VCP, CCDC8, EED, RNF2, KRR1, MRPL18, MRPL24, NOC4L, RPL10, RPL13, RPL13A, RPL27A, RPL28, RPL32, RPL35A, RPL37, RPL38, DIMT1, RPL26, RPL27, RPL3, RPL34, RPL36, RPL8, RPS15, RPS18, RPS25, LOC101929876, RPS27, RPSA, RSL1D1, SFN, HSPB2, XPO1, AHSA1, NPM1, MPHOSPH8, CENPQ, VPS16, MMGT1, Eif3a, Eif3e, Srp72, Rrbp1, MCM2, Ksr1, RC3H1, ZNF746, PSMG3, MDM2, EEF1A2, RPL26L1, NAT10, TOP1, TOP2A, TOP3A, IMPDH1, CDC7, CDK9, MAPK1, CYLD, TRIM25, BRCA1, MTF1, FBXO7, TMPO, PPP1CC, PPP2R2A, PPP2R2D, PHLPP2, PPP1R16B, ILKAP, PPP4R2, ACO2, TGFB1, ADSS, BMP4, CTNNB1, UBE2M, PRPF8, AAR2, PIH1D1, EFTUD2, TNIP2, SOCS2, CHD3, CHD4, LARP7, RIOK1, BPLF1, HEXIM1, MEPCE, SNAI1, AGR2, RECQL4, DCPS, REST, ZFP36L2, MYC, Prkaa1, Prkab1, C1orf106, GRWD1, METTL14, EIF4B, DCAF13, RC3H2, PHB, NR2C2, GBF1, CTCF, ZDHHC18, ZDHHC23, KRAS, VRK1, HIST1H4A, SNRNP70, ITFG1, ARAF, HMGB1, BIRC3, STAU1, NFX1, WWP2, MATR3, SOX2, TRIM28, CMTR1, PLEKHA4, FANCD2, PTEN, HCVgp1, ZC3H18, MAP3K14, ALPK3, PRR13, ITPR3, SNIP1, M, nsp13, nsp4, nsp5, nsp6, ORF3a, ORF7a, ORF7b, CIT, ANLN, AURKB, CHMP4B, CHMP4C, ECT2, KIF14, KIF20A, KIF23, PRC1, INS, BRD4, CIC, N, Apc2, RBM39, FBP1, MKRN1, LGALS9, CUL4A, USP15, RIN3, DDX58, AR, PARK2, UFL1, DDRGK1, LCK, PANX1, PARP1, RHOB, TRIM37, ATG10, ATG3, WDR5, PAGE4, NAA40, PSME3, FAM192A, SSSCA1, PRKRA, SPRTN, BTF3, FBXW7, UBR5, RCHY1, CCNF, CALCOCO2, PSMD9, CPEB1, GLI3, KLF15, KLF16, KLF4, KLF5, KLF8, SOX5, SOX6, TLX1,

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Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
RPS11	COAD	chr19	50000840	50000840	C	T	Missense_Mutation	p.R71W	4
RPS11	PAAD	chr19	50001263	50001263	C	T	Missense_Mutation	p.R105C	3
RPS11	SKCM	chr19	50000830	50000830	C	T	Silent	p.S67S	2
RPS11	ESCA	chr19	50000798	50000798	G	T	Missense_Mutation	p.D57Y	2
RPS11	PAAD	chr19	50001263	50001263	C	T	Missense_Mutation		2
RPS11	PRAD	chr19	50000530	50000530	A	C	Missense_Mutation	p.K32T	2
RPS11	UCEC	chr19	50002863	50002863	G	A	Missense_Mutation	p.G150S	2
RPS11	PRAD	chr19	50002830	50002830	C	A	Missense_Mutation	p.R139S	2
RPS11	SKCM	chr19	50001293	50001293	C	T	Missense_Mutation	p.P115S	2
RPS11	LIHC	chr19	50000488	50000488	A	-	Frame_Shift_Del	p.Q18fs	2
RPS11	LIHC	chr19	50002775	50002775	C	-	Frame_Shift_Del	p.V120fs	1
RPS11	SKCM	chr19	50001235	50001235	C	A	Nonsense_Mutation	p.Y95*	1
RPS11	ESCA	chr19	50002780	50002781	-	CG	Frame_Shift_Ins	p.G123fs	1
RPS11	LIHC	chr19	50000484	50000484	T	-	Frame_Shift_Del	p.F17fs	1
RPS11	STAD	chr19	50000524	50000526	AGG	-	In_Frame_Del	p.30_30del	1
RPS11	ESCA	chr19	50002780	50002781	-	-	Frame_Shift_Ins		1
RPS11	LUAD	chr19	50002824	50002824	A	G	Missense_Mutation	p.T137A	1
RPS11	STAD	chr19	50001234	50001234	A	G	Missense_Mutation	p.Y95C	1
RPS11	ESCA	chr19	50000798	50000798	G	T	Missense_Mutation		1
RPS11	LUSC	chr19	50000835	50000835	G	C	Missense_Mutation	p.R69P	1
RPS11	STAD	chr19	50000524	50000526	AGG	-	In_Frame_Del	p.K30del	1
RPS11	ESCA	chr19	50000783	50000783	G	T	Nonsense_Mutation	p.E52X	1
RPS11	PAAD	chr19	50000840	50000840	C	T	Missense_Mutation		1
RPS11	THCA	chr19	50001239	50001239	C	A	Missense_Mutation		1
RPS11	ESCA	chr19	50002780	50002781	-	CG	Frame_Shift_Ins	p.R122fs	1
RPS11	THYM	chr19	50000775	50000775	A	G	Splice_Site	.	1
RPS11	HNSC	chr19	50002790	50002790	C	T	Silent	p.I125I	1
RPS11	THYM	chr19	50002864	50002864	G	A	Missense_Mutation	p.G150D	1
RPS11	KIRC	chr19	50001200	50001200	A	G	Missense_Mutation	p.R84G	1
RPS11	BLCA	chr19	50001257	50001257	G	C	Missense_Mutation		1
RPS11	LGG	chr19	50001210	50001210	T	C	Missense_Mutation	p.V87A	1
RPS11	LGG	chr19	50001210	50001210	T	C	Missense_Mutation		1
RPS11	COAD	chr19	50001265	50001265	C	T	Silent	p.R105R	1

Copy number variation (CNV) of RPS11
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across RPS11
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
102430	N/A	AW024049	AC012593.1	chr2	35181208	-	RPS11	chr19	50000498	+
102430	N/A	AA483349	ATAD2B	chr2	24070859	-	RPS11	chr19	50002946	-
102430	N/A	AA470975	CCDC134	chr22	42202241	+	RPS11	chr19	50002946	-
102430	N/A	BI495094	CSE1L	chr20	47664908	+	RPS11	chr19	50002946	-
102430	ACC	TCGA-OR-A5LC-01A	DLK1	chr14	101200728	+	RPS11	chr19	50001254	+
102430	N/A	AA368503	DLK1	chr14	101201247	-	RPS11	chr19	50000561	+
102430	OV	TCGA-24-1431-01A	EEF1A1	chr6	74227858	-	RPS11	chr19	49999707	+
102430	BLCA	TCGA-DK-A1AE-01A	GOLGA3	chr12	133402284	-	RPS11	chr19	49999668	+
102430	BLCA	TCGA-S5-AA26-01A	GOLGA3	chr12	133402500	-	RPS11	chr19	50001191	+
102430	BRCA	TCGA-A2-A04U-01A	GOLGA3	chr12	133402500	-	RPS11	chr19	50001192	+
102430	BRCA	TCGA-A2-A25A-01A	GOLGA3	chr12	133402492	-	RPS11	chr19	50001186	+
102430	BRCA	TCGA-A8-A06T-01A	GOLGA3	chr12	133402285	-	RPS11	chr19	49999640	+
102430	BRCA	TCGA-A8-A099-01A	GOLGA3	chr12	133402805	-	RPS11	chr19	49999694	+
102430	BRCA	TCGA-AC-A2FK-01A	GOLGA3	chr12	133402414	-	RPS11	chr19	50001187	+
102430	BRCA	TCGA-AR-A255-01A	GOLGA3	chr12	133402494	-	RPS11	chr19	50001187	+
102430	BRCA	TCGA-AR-A2LE-01A	GOLGA3	chr12	133402500	-	RPS11	chr19	50001185	+
102430	BRCA	TCGA-B6-A0RM-01A	GOLGA3	chr12	133402285	-	RPS11	chr19	50000533	+
102430	BRCA	TCGA-BH-A0BD-01A	GOLGA3	chr12	133402493	-	RPS11	chr19	50001185	+
102430	BRCA	TCGA-BH-A18L-11A	GOLGA3	chr12	133402498	-	RPS11	chr19	50001194	+
102430	BRCA	TCGA-C8-A26V-01A	GOLGA3	chr12	133402285	-	RPS11	chr19	50000535	+
102430	BRCA	TCGA-C8-A27B-01A	GOLGA3	chr12	133402494	-	RPS11	chr19	50000533	+
102430	BRCA	TCGA-D8-A1JG-01B	GOLGA3	chr12	133402284	-	RPS11	chr19	50000533	+
102430	BRCA	TCGA-D8-A1XM-01A	GOLGA3	chr12	133402490	-	RPS11	chr19	50001186	+
102430	BRCA	TCGA-D8-A1Y1-01A	GOLGA3	chr12	133402497	-	RPS11	chr19	50000535	+
102430	BRCA	TCGA-E2-A10B-01A	GOLGA3	chr12	133402490	-	RPS11	chr19	50001188	+
102430	BRCA	TCGA-E2-A1LS-11A	GOLGA3	chr12	133402418	-	RPS11	chr19	50000814	+
102430	BRCA	TCGA-E9-A1NG-01A	GOLGA3	chr12	133402502	-	RPS11	chr19	50001203	+
102430	BRCA	TCGA-EW-A1OX-01A	GOLGA3	chr12	133402419	-	RPS11	chr19	50000533	+
102430	BRCA	TCGA-GM-A2DA-01A	GOLGA3	chr12	133402291	-	RPS11	chr19	49999669	+
102430	BRCA	TCGA-OL-A5D8-01A	GOLGA3	chr12	133402283	-	RPS11	chr19	49999662	+
102430	CESC	TCGA-FU-A23L-01A	GOLGA3	chr12	133402496	-	RPS11	chr19	50001185	+
102430	HNSC	TCGA-BB-4227-01A	GOLGA3	chr12	133402292	-	RPS11	chr19	49999672	+
102430	HNSC	TCGA-MT-A7BN-01A	GOLGA3	chr12	133402492	-	RPS11	chr19	50001185	+
102430	KIRC	TCGA-CJ-4897-01A	GOLGA3	chr12	133402281	-	RPS11	chr19	49999697	+
102430	KIRC	TCGA-CW-5585-11A	GOLGA3	chr12	133402282	-	RPS11	chr19	49999691	+
102430	LGG	TCGA-CS-4941-01A	GOLGA3	chr12	133402422	-	RPS11	chr19	50001190	+
102430	LGG	TCGA-DB-A4XD-01A	GOLGA3	chr12	133402493	-	RPS11	chr19	50000534	+
102430	LGG	TCGA-DH-A7UU-01A	GOLGA3	chr12	133402499	-	RPS11	chr19	50001192	+
102430	LGG	TCGA-HT-8110-01A	GOLGA3	chr12	133402287	-	RPS11	chr19	50000534	+
102430	LUAD	TCGA-50-5942-01A	GOLGA3	chr12	133402287	-	RPS11	chr19	50000535	+
102430	LUAD	TCGA-50-6593-01A	GOLGA3	chr12	133402413	-	RPS11	chr19	50000532	+
102430	LUAD	TCGA-50-6594-01A	GOLGA3	chr12	133402285	-	RPS11	chr19	50000534	+
102430	LUAD	TCGA-55-6642-01A	GOLGA3	chr12	133402498	-	RPS11	chr19	50001370	+
102430	LUAD	TCGA-55-6972-01A	GOLGA3	chr12	133402500	-	RPS11	chr19	50001203	+
102430	LUAD	TCGA-55-6984-01A	GOLGA3	chr12	133402492	-	RPS11	chr19	50000813	+
102430	LUAD	TCGA-55-8616-01A	GOLGA3	chr12	133402284	-	RPS11	chr19	50000534	+
102430	LUAD	TCGA-69-7973-01A	GOLGA3	chr12	133402494	-	RPS11	chr19	50001188	+
102430	LUAD	TCGA-69-8255-01A	GOLGA3	chr12	133402501	-	RPS11	chr19	50001193	+
102430	LUAD	TCGA-75-5126-01A	GOLGA3	chr12	133402416	-	RPS11	chr19	50001192	+
102430	LUAD	TCGA-78-7156-01A	GOLGA3	chr12	133402503	-	RPS11	chr19	50001191	+
102430	LUAD	TCGA-93-A4JN-01A	GOLGA3	chr12	133402491	-	RPS11	chr19	50000814	+
102430	LUAD	TCGA-93-A4JQ-01A	GOLGA3	chr12	133402491	-	RPS11	chr19	50000532	+
102430	LUSC	TCGA-43-7658-01A	GOLGA3	chr12	133402495	-	RPS11	chr19	50001187	+
102430	LUSC	TCGA-56-A5DS-01A	GOLGA3	chr12	133402282	-	RPS11	chr19	49999699	+
102430	LUSC	TCGA-66-2792-01A	GOLGA3	chr12	133402500	-	RPS11	chr19	50000731	+
102430	LUSC	TCGA-O2-A52S-01A	GOLGA3	chr12	133402285	-	RPS11	chr19	49999667	+
102430	OV	TCGA-04-1343-01A	GOLGA3	chr12	133402468	-	RPS11	chr19	50001193	+
102430	OV	TCGA-09-0369-01A	GOLGA3	chr12	133402503	-	RPS11	chr19	50001188	+
102430	OV	TCGA-20-1685-01A	GOLGA3	chr12	133402494	-	RPS11	chr19	50000535	+
102430	PRAD	TCGA-EJ-A7NJ-01A	GOLGA3	chr12	133402284	-	RPS11	chr19	49999682	+
102430	PRAD	TCGA-KC-A7FA-01A	GOLGA3	chr12	133402284	-	RPS11	chr19	49999683	+
102430	PRAD	TCGA-KC-A7FA-01A	GOLGA3	chr12	133402417	-	RPS11	chr19	50000562	+
102430	PRAD	TCGA-KK-A59Z-01A	GOLGA3	chr12	133402418	-	RPS11	chr19	49999693	+
102430	PRAD	TCGA-KK-A7B1-01A	GOLGA3	chr12	133402281	-	RPS11	chr19	49999644	+
102430	PRAD	TCGA-KK-A8I8-01A	GOLGA3	chr12	133402501	-	RPS11	chr19	50001192	+
102430	PRAD	TCGA-WW-A8ZI-01A	GOLGA3	chr12	133402290	-	RPS11	chr19	49999673	+
102430	PRAD	TCGA-YL-A8HO-01A	GOLGA3	chr12	133402416	-	RPS11	chr19	50001188	+
102430	PRAD	TCGA-ZG-A9NI-01A	GOLGA3	chr12	133402420	-	RPS11	chr19	49999699	+
102430	SARC	TCGA-UE-A6QU-01A	GOLGA3	chr12	133402490	-	RPS11	chr19	50000813	+
102430	STAD	TCGA-2H-A9GL-01A8	GOLGA3	chr12	133402419	-	RPS11	chr19	49999664	+
102430	STAD	TCGA-2H-A9GL-01A8	GOLGA3	chr12	133402504	-	RPS11	chr19	50001189	+
102430	STAD	TCGA-HU-A4GJ-01A	GOLGA3	chr12	133402497	-	RPS11	chr19	50001251	+
102430	STAD	TCGA-LN-A4MR-01A6	GOLGA3	chr12	133402493	-	RPS11	chr19	50000742	+
102430	STAD	TCGA-LN-A5U5-01A3	GOLGA3	chr12	133402283	-	RPS11	chr19	50000762	+
102430	STAD	TCGA-LN-A5U5-01A3	GOLGA3	chr12	133402504	-	RPS11	chr19	50001187	+
102430	STAD	TCGA-LN-A5U7-01A1	GOLGA3	chr12	133402413	-	RPS11	chr19	49999670	+
102430	STAD	TCGA-LN-A7HY-01A7	GOLGA3	chr12	133402502	-	RPS11	chr19	50001189	+
102430	STAD	TCGA-LN-A7HY-01A7	GOLGA3	chr12	133402503	-	RPS11	chr19	50001189	+
102430	STAD	TCGA-LN-A9FQ-01A6	GOLGA3	chr12	133402281	-	RPS11	chr19	50000765	+
102430	STAD	TCGA-Q9-A6FW-01A7	GOLGA3	chr12	133402415	-	RPS11	chr19	49999668	+
102430	THYM	TCGA-YT-A95D-01A	GOLGA3	chr12	133402490	-	RPS11	chr19	50000814	+
102430	UCEC	TCGA-A5-A2K3-01A	GOLGA3	chr12	133402414	-	RPS11	chr19	50001193	+
102430	N/A	AA229812	GOLGA3	chr12	133402362	-	RPS11	chr19	50002946	-
102430	N/A	AI799860	GOLGA3	chr12	133402277	-	RPS11	chr19	50002946	-
102430	N/A	CF130421	GOLGA3	chr12	133402787	-	RPS11	chr19	50001201	+
102430	N/A	AA533259	HRK	chr12	117309410	-	RPS11	chr19	50002946	-
102430	N/A	AA523319	IFT46	chr11	118419101	+	RPS11	chr19	50002946	-
102430	N/A	BM822653	NDUFB4	chr3	120320086	+	RPS11	chr19	49999688	+
99844	N/A	EC448789	RPS11	chr19	50002906	-	ACVR2B	chr3	38524703	+
77325	N/A	BF245432	RPS11	chr19	50002946	+	FBXO36	chr2	230822990	-
88813	LAML	TCGA-AB-2912	RPS11	chr19	50001303	+	FLT3LG	chr19	49977859	+
88813	LAML	TCGA-AB-2912_613RTAAXX_6	RPS11	chr19	50001303	+	FLT3LG	chr19	49977860	+
92827	LAML	TCGA-AB-2999-03B	RPS11	chr19	50000557	+	GOLGA3	chr12	133402448	-
92827	LUAD	TCGA-49-4486-01A	RPS11	chr19	50001213	+	GOLGA3	chr12	133402521	-
92827	OV	TCGA-09-0367-01A	RPS11	chr19	50001211	+	GOLGA3	chr12	133402514	-
92827	OV	TCGA-09-0367-01A	RPS11	chr19	50001225	+	GOLGA3	chr12	133402648	-
92827	N/A	AA551948	RPS11	chr19	50002946	+	GOLGA3	chr12	133402485	+
92827	N/A	AA564620	RPS11	chr19	50000449	-	GOLGA3	chr12	133402823	-
92827	N/A	AA888242	RPS11	chr19	50002944	+	GOLGA3	chr12	133402589	+
92827	N/A	BF217900	RPS11	chr19	50002946	+	GOLGA3	chr12	133402825	+
92827	N/A	BG033601	RPS11	chr19	50002946	+	GOLGA3	chr12	133402267	+
92827	N/A	BP224971	RPS11	chr19	50002942	+	GOLGA3	chr12	133402267	+
98346	N/A	BG029450	RPS11	chr19	50002946	+	GYS1	chr19	49479178	+
97992	N/A	AA552757	RPS11	chr19	50002946	+	HIC2	chr22	21786966	+
77325	LUSC	TCGA-66-2771	RPS11	chr19	50000565	+	IGHG1	chr14	106208527	-
77325	N/A	AI589684	RPS11	chr19	50002861	-	LIPC	chr15	58805407	-
90686	N/A	DL052261	RPS11	chr19	50002906	-	LRIG1	chr3	66433728	+
96498	N/A	EC446455	RPS11	chr19	50002865	-	MAML3	chr4	140843728	-
87949	N/A	BP226032	RPS11	chr19	50002945	+	MTDH	chr8	98701958	-
101597	N/A	BF687509	RPS11	chr19	50002945	+	PARK2	chr6	162728429	+
81458	BRCA	TCGA-B6-A3ZX	RPS11	chr19	50001303	+	RUVBL2	chr19	49517740	+
95094	STAD	TCGA-CD-A48C-01A	RPS11	chr19	50002941	+	S100A11	chr1	152005030	-
89927	GBM	TCGA-32-5222-01A	RPS11	chr19	50001303	+	TEAD2	chr19	49854622	-
101989	N/A	AA533787	RPS11	chr19	50002946	+	TPK1	chr7	144521505	+
95192	N/A	BF244409	RPS11	chr19	50002943	+	TSHR	chr14	81466395	-
98632	SKCM	TCGA-EE-A29B-06A	RPS11	chr19	50000812	+	VIM	chr10	17271964	+
102430	N/A	BG222628	SHANK2	chr11	70837262	-	RPS11	chr19	50002946	-
102430	STAD	TCGA-BR-8372-01A	TPM3	chr1	154143125	-	RPS11	chr19	50000777	+
102430	N/A	AA531474	TRAPPC8	chr18	29486263	-	RPS11	chr19	50002947	-
102431	STAD	TCGA-BR-8078-01A	ZNF577	chr19	52390074	-	RPS11	chr19	50001174	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRC	RPS11	0.00358801941320753	0.1
SARC	RPS11	0.016577226467362	0.45

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
BRCA	RPS11	0.015250700506575	0.49
PAAD	RPS11	0.0148191744646941	0.49

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source