Home

Download

Statistics

Examples

Help

Contact

	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: RPS24 (NCBI Gene ID:6229)

Gene Summary

Gene Summary

Gene Information	Gene Name: RPS24
	Gene ID: 6229
	Gene Symbol	RPS24
	Gene ID	6229
	Gene Name	ribosomal protein S24
	Synonyms	DBA3\|S24\|eS24
	Cytomap	10q22.3
	Type of Gene	protein-coding
	Description	40S ribosomal protein S24small ribosomal subunit protein eS24
	Modification date	20200313
	UniProtAcc	P62847

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0002181	Cytoplasmic translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
RPS24	>1119.25

Top

Translation Studies in PubMed

We searched PubMed using 'RPS24[title] AND translation [title] AND human.'

Gene	Title	PMID
RPS24	.	.

Top

Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

ORF

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

Top

Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
BRCA	RPS24	-2.39554944754566	0.000117697958041698
PRAD	RPS24	1.80095071289163	0.00246137516089789
BLCA	RPS24	-1.7374699818168	0.0258216857910156
KIRC	RPS24	-2.03004684849548	3.10358016139282e-10

Top

Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
PAAD	RPS24	3	2	0.0174018099533935	0.638596698113208	0.533180617977528	-0.324194986123607	-0.210468528629397
PCPG	RPS24	3	2	0.030821705997126	0.624675	0.400890857142857	-0.0211174561065454	-0.319121767794658
TGCT	RPS24	3	2	0.0467685216962742	0.656333673469388	0.443288636363636	1.09755545669593	0.870817897429576

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
CHOL	RPS24	-0.045566689	0.032484446
KIRC	RPS24	0.027733925	0.045471583

Top

Associated Genes

Strongly correlated genes belong to cellular important gene groups with RPS24 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
CHOL	CGC	RPS24	NACA	0.834546661	1.06E-12
DLBC	Cell metabolism gene	RPS24	POLR2L	0.803909585	5.99E-12
DLBC	Cell metabolism gene	RPS24	PFDN5	0.805212644	5.22E-12
DLBC	Cell metabolism gene	RPS24	PTDSS2	0.815878557	1.62E-12
DLBC	Cell metabolism gene	RPS24	POLR2F	0.824014778	6.28E-13
DLBC	Cell metabolism gene	RPS24	TOMM22	0.836482131	1.34E-13
DLBC	Cell metabolism gene	RPS24	FAU	0.850198088	2.08E-14
DLBC	Cell metabolism gene	RPS24	SNRPD2	0.87053822	9.12E-16
DLBC	Cell metabolism gene	RPS24	NME2	0.87205498	7.07E-16
DLBC	CGC	RPS24	NACA	0.878830899	2.18E-16
DLBC	Epifactor	RPS24	FBL	0.846900768	3.31E-14
DLBC	TF	RPS24	NME2	0.87205498	7.07E-16
DLBC	TSG	RPS24	GADD45GIP1	0.805925793	4.84E-12
DLBC	TSG	RPS24	PARK7	0.812428858	2.38E-12
DLBC	TSG	RPS24	GNB2L1	0.861333013	3.99E-15
KIRP	Cell metabolism gene	RPS24	SNRPD2	0.80944568	3.30E-76
LGG	Cell metabolism gene	RPS24	IMPDH2	0.810569026	8.74E-125
LGG	Cell metabolism gene	RPS24	FAU	0.852892014	3.78E-151
LGG	CGC	RPS24	NACA	0.895179456	1.93E-187
LGG	IUPHAR	RPS24	IMPDH2	0.810569026	8.74E-125
LGG	TSG	RPS24	GNB2L1	0.809650644	2.74E-124
LGG	TSG	RPS24	GAS5	0.844566717	2.38E-145
LIHC	TSG	RPS24	GNB2L1	0.804085117	4.04E-97
PCPG	Cell metabolism gene	RPS24	PFDN5	0.820147578	9.83E-47
PCPG	CGC	RPS24	NACA	0.845666192	2.46E-52
PCPG	TSG	RPS24	GNB2L1	0.843004135	1.05E-51
PRAD	Cell metabolism gene	RPS24	TIMM9	0.828108252	7.28E-140
PRAD	CGC	RPS24	NACA	0.838803184	8.07E-147
PRAD	Epifactor	RPS24	FBL	0.819382228	1.55E-134
PRAD	TSG	RPS24	GAS5	0.835928487	6.69E-145
PRAD	TSG	RPS24	GNB2L1	0.851833996	5.13E-156
THCA	Cell metabolism gene	RPS24	FAU	0.824008759	9.23E-143
THCA	Cell metabolism gene	RPS24	PFDN5	0.824954084	2.30E-143
THCA	Cell metabolism gene	RPS24	SNRPD2	0.84945924	2.16E-160
THCA	Epifactor	RPS24	FBL	0.814879029	4.06E-137
THCA	TSG	RPS24	GNB2L1	0.836624072	4.03E-151
THYM	Cell metabolism gene	RPS24	POLR2J	0.801114991	1.60E-28
THYM	Cell metabolism gene	RPS24	LSM4	0.804366687	6.61E-29
THYM	Cell metabolism gene	RPS24	DGUOK	0.805116733	5.38E-29
THYM	Cell metabolism gene	RPS24	SNRPD1	0.805620219	4.68E-29
THYM	Cell metabolism gene	RPS24	GFER	0.805943397	4.28E-29
THYM	Cell metabolism gene	RPS24	SMPD2	0.810513782	1.18E-29
THYM	Cell metabolism gene	RPS24	PFDN6	0.81102183	1.02E-29
THYM	Cell metabolism gene	RPS24	TIMM50	0.814505665	3.75E-30
THYM	Cell metabolism gene	RPS24	ACOT8	0.815255531	3.01E-30
THYM	Cell metabolism gene	RPS24	PSMB1	0.819784286	7.85E-31
THYM	Cell metabolism gene	RPS24	APRT	0.824074513	2.12E-31
THYM	Cell metabolism gene	RPS24	SNRPF	0.826153537	1.11E-31
THYM	Cell metabolism gene	RPS24	POLR2I	0.826984748	8.54E-32
THYM	Cell metabolism gene	RPS24	PSMB3	0.828030768	6.14E-32
THYM	Cell metabolism gene	RPS24	POLR2F	0.828761191	4.86E-32
THYM	Cell metabolism gene	RPS24	DPM2	0.829416096	3.95E-32
THYM	Cell metabolism gene	RPS24	PGLS	0.832135284	1.64E-32
THYM	Cell metabolism gene	RPS24	PSMD13	0.835770339	4.94E-33
THYM	Cell metabolism gene	RPS24	EXOSC1	0.837222001	3.04E-33
THYM	Cell metabolism gene	RPS24	PSMC3	0.837557495	2.71E-33
THYM	Cell metabolism gene	RPS24	ITPA	0.839914848	1.22E-33
THYM	Cell metabolism gene	RPS24	SSR2	0.841062908	8.18E-34
THYM	Cell metabolism gene	RPS24	POLR2H	0.842396709	5.15E-34
THYM	Cell metabolism gene	RPS24	SNRPD3	0.844758479	2.24E-34
THYM	Cell metabolism gene	RPS24	TIMM13	0.845496159	1.72E-34
THYM	Cell metabolism gene	RPS24	PSMB7	0.852479795	1.34E-35
THYM	Cell metabolism gene	RPS24	LSM2	0.858089594	1.55E-36
THYM	Cell metabolism gene	RPS24	SLC27A5	0.870015504	1.16E-38
THYM	Cell metabolism gene	RPS24	SNRPD2	0.88008172	1.26E-40
THYM	Cell metabolism gene	RPS24	TIMM8B	0.889140118	1.49E-42
THYM	Cell metabolism gene	RPS24	PFDN5	0.892089121	3.24E-43
THYM	Cell metabolism gene	RPS24	FAU	0.904140857	3.84E-46
THYM	Epifactor	RPS24	SS18L2	0.800730795	1.78E-28
THYM	Epifactor	RPS24	CCDC101	0.803271939	8.92E-29
THYM	Epifactor	RPS24	INO80E	0.805154533	5.32E-29
THYM	Epifactor	RPS24	MBD3	0.807836897	2.52E-29
THYM	Epifactor	RPS24	PRPF31	0.813031207	5.75E-30
THYM	Epifactor	RPS24	C17orf49	0.818404266	1.19E-30
THYM	Epifactor	RPS24	NOC2L	0.820107282	7.12E-31
THYM	Epifactor	RPS24	PPP4C	0.822141989	3.84E-31
THYM	Epifactor	RPS24	ZNHIT1	0.825000722	1.59E-31
THYM	Epifactor	RPS24	RUVBL2	0.829839857	3.44E-32
THYM	Epifactor	RPS24	BRMS1	0.830148061	3.12E-32
THYM	Epifactor	RPS24	EXOSC1	0.837222001	3.04E-33
THYM	Epifactor	RPS24	SIRT6	0.856160961	3.29E-36
THYM	Epifactor	RPS24	TAF10	0.861900525	3.42E-37
THYM	Epifactor	RPS24	FBL	0.8846871	1.38E-41
THYM	IUPHAR	RPS24	CSNK2B	0.800038683	2.14E-28
THYM	IUPHAR	RPS24	PPIA	0.800848837	1.72E-28
THYM	IUPHAR	RPS24	SMPD2	0.810513782	1.18E-29
THYM	IUPHAR	RPS24	PSMB1	0.819784286	7.85E-31
THYM	IUPHAR	RPS24	SIRT6	0.856160961	3.29E-36
THYM	IUPHAR	RPS24	SLC27A5	0.870015504	1.16E-38
THYM	TF	RPS24	THYN1	0.800446829	1.92E-28
THYM	TF	RPS24	MBD3	0.807836897	2.52E-29
THYM	TF	RPS24	THAP3	0.828553546	5.20E-32
THYM	TF	RPS24	ZNF511	0.829196728	4.23E-32
THYM	TF	RPS24	ZNF787	0.831865527	1.79E-32
THYM	TF	RPS24	ZNF428	0.864698639	1.09E-37
THYM	TF	RPS24	ZNF32	0.86556067	7.64E-38
THYM	TSG	RPS24	NPRL2	0.802141719	1.21E-28
THYM	TSG	RPS24	PARK7	0.821678367	4.42E-31
THYM	TSG	RPS24	TSSC4	0.826446318	1.01E-31
THYM	TSG	RPS24	GLTSCR2	0.828981683	4.53E-32
THYM	TSG	RPS24	BRMS1	0.830148061	3.12E-32
THYM	TSG	RPS24	GADD45GIP1	0.836439746	3.95E-33
THYM	TSG	RPS24	SIRT6	0.856160961	3.29E-36
THYM	TSG	RPS24	GNB2L1	0.881601405	6.13E-41
UCS	Cell metabolism gene	RPS24	POLR2J	0.801114991	1.60E-28
UCS	Cell metabolism gene	RPS24	LSM4	0.804366687	6.61E-29
UCS	Cell metabolism gene	RPS24	DGUOK	0.805116733	5.38E-29
UCS	Cell metabolism gene	RPS24	SNRPD1	0.805620219	4.68E-29
UCS	Cell metabolism gene	RPS24	GFER	0.805943397	4.28E-29
UCS	Cell metabolism gene	RPS24	SMPD2	0.810513782	1.18E-29
UCS	Cell metabolism gene	RPS24	PFDN6	0.81102183	1.02E-29
UCS	Cell metabolism gene	RPS24	TIMM50	0.814505665	3.75E-30
UCS	Cell metabolism gene	RPS24	ACOT8	0.815255531	3.01E-30
UCS	Cell metabolism gene	RPS24	PSMB1	0.819784286	7.85E-31
UCS	Cell metabolism gene	RPS24	APRT	0.824074513	2.12E-31
UCS	Cell metabolism gene	RPS24	SNRPF	0.826153537	1.11E-31
UCS	Cell metabolism gene	RPS24	POLR2I	0.826984748	8.54E-32
UCS	Cell metabolism gene	RPS24	PSMB3	0.828030768	6.14E-32
UCS	Cell metabolism gene	RPS24	POLR2F	0.828761191	4.86E-32
UCS	Cell metabolism gene	RPS24	DPM2	0.829416096	3.95E-32
UCS	Cell metabolism gene	RPS24	PGLS	0.832135284	1.64E-32
UCS	Cell metabolism gene	RPS24	PSMD13	0.835770339	4.94E-33
UCS	Cell metabolism gene	RPS24	EXOSC1	0.837222001	3.04E-33
UCS	Cell metabolism gene	RPS24	PSMC3	0.837557495	2.71E-33
UCS	Cell metabolism gene	RPS24	ITPA	0.839914848	1.22E-33
UCS	Cell metabolism gene	RPS24	SSR2	0.841062908	8.18E-34
UCS	Cell metabolism gene	RPS24	POLR2H	0.842396709	5.15E-34
UCS	Cell metabolism gene	RPS24	SNRPD3	0.844758479	2.24E-34
UCS	Cell metabolism gene	RPS24	TIMM13	0.845496159	1.72E-34
UCS	Cell metabolism gene	RPS24	PSMB7	0.852479795	1.34E-35
UCS	Cell metabolism gene	RPS24	LSM2	0.858089594	1.55E-36
UCS	Cell metabolism gene	RPS24	SLC27A5	0.870015504	1.16E-38
UCS	Cell metabolism gene	RPS24	SNRPD2	0.88008172	1.26E-40
UCS	Cell metabolism gene	RPS24	TIMM8B	0.889140118	1.49E-42
UCS	Cell metabolism gene	RPS24	PFDN5	0.892089121	3.24E-43
UCS	Cell metabolism gene	RPS24	FAU	0.904140857	3.84E-46
UCS	Epifactor	RPS24	SS18L2	0.800730795	1.78E-28
UCS	Epifactor	RPS24	CCDC101	0.803271939	8.92E-29
UCS	Epifactor	RPS24	INO80E	0.805154533	5.32E-29
UCS	Epifactor	RPS24	MBD3	0.807836897	2.52E-29
UCS	Epifactor	RPS24	PRPF31	0.813031207	5.75E-30
UCS	Epifactor	RPS24	C17orf49	0.818404266	1.19E-30
UCS	Epifactor	RPS24	NOC2L	0.820107282	7.12E-31
UCS	Epifactor	RPS24	PPP4C	0.822141989	3.84E-31
UCS	Epifactor	RPS24	ZNHIT1	0.825000722	1.59E-31
UCS	Epifactor	RPS24	RUVBL2	0.829839857	3.44E-32
UCS	Epifactor	RPS24	BRMS1	0.830148061	3.12E-32
UCS	Epifactor	RPS24	EXOSC1	0.837222001	3.04E-33
UCS	Epifactor	RPS24	SIRT6	0.856160961	3.29E-36
UCS	Epifactor	RPS24	TAF10	0.861900525	3.42E-37
UCS	Epifactor	RPS24	FBL	0.8846871	1.38E-41
UCS	IUPHAR	RPS24	CSNK2B	0.800038683	2.14E-28
UCS	IUPHAR	RPS24	PPIA	0.800848837	1.72E-28
UCS	IUPHAR	RPS24	SMPD2	0.810513782	1.18E-29
UCS	IUPHAR	RPS24	PSMB1	0.819784286	7.85E-31
UCS	IUPHAR	RPS24	SIRT6	0.856160961	3.29E-36
UCS	IUPHAR	RPS24	SLC27A5	0.870015504	1.16E-38
UCS	TF	RPS24	THYN1	0.800446829	1.92E-28
UCS	TF	RPS24	MBD3	0.807836897	2.52E-29
UCS	TF	RPS24	THAP3	0.828553546	5.20E-32
UCS	TF	RPS24	ZNF511	0.829196728	4.23E-32
UCS	TF	RPS24	ZNF787	0.831865527	1.79E-32
UCS	TF	RPS24	ZNF428	0.864698639	1.09E-37
UCS	TF	RPS24	ZNF32	0.86556067	7.64E-38
UCS	TSG	RPS24	NPRL2	0.802141719	1.21E-28
UCS	TSG	RPS24	PARK7	0.821678367	4.42E-31
UCS	TSG	RPS24	TSSC4	0.826446318	1.01E-31
UCS	TSG	RPS24	GLTSCR2	0.828981683	4.53E-32
UCS	TSG	RPS24	BRMS1	0.830148061	3.12E-32
UCS	TSG	RPS24	GADD45GIP1	0.836439746	3.95E-33
UCS	TSG	RPS24	SIRT6	0.856160961	3.29E-36
UCS	TSG	RPS24	GNB2L1	0.881601405	6.13E-41
UVM	Cell metabolism gene	RPS24	TIMM9	0.857257939	3.41E-24
UVM	CGC	RPS24	NACA	0.860544884	1.47E-24
UVM	Epifactor	RPS24	NAP1L1	0.81351342	4.77E-20
UVM	TSG	RPS24	RBMX	0.803588887	2.95E-19
UVM	TSG	RPS24	GAS5	0.874221364	3.43E-26

Top

Protein structure

Protein 3D structure
Visit iCn3D.

Top

Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
KIRP	RPS24	RPL18A	-1.51651392808885	0.00016188295558095
KICH	RPS24	RPS27A	1.75396693785956	0.000187873840332031
KIRP	RPS24	RPS16	-1.35957043617517	0.00019507110118866
COAD	RPS24	RPS3	1.48730375143014	0.000411599874496461
KIRP	RPS24	RPS11	-1.01861570565103	0.00105937570333481
LIHC	RPS24	RPL8	-4.84588284974558	0.00110314154326131
PRAD	RPS24	RPL18A	1.40600175748499	0.00205137828390396
KICH	RPS24	RPL19	1.36901182894089	0.00250792503356934
KICH	RPS24	RPS12	1.26997381758431	0.00308787822723389
LUAD	RPS24	RPL19	-1.31398026615725	0.00993159558412698
THCA	RPS24	RPS16	-6.16322798156577	0.0115764821363307
BLCA	RPS24	RPS12	-1.47804673440421	0.0204124450683594
BLCA	RPS24	RPS27A	-1.04747470069188	0.0258216857910156
HNSC	RPS24	RPS3	-4.73505819095135	0.0273726439852453
COAD	RPS24	RPS11	1.35307548998204	0.0312207043170929
LUSC	RPS24	RPL19	-2.14669889516666	0.044366810398747
KIRC	RPS24	RPL19	-2.73485271276676	1.33980982873695e-10
BRCA	RPS24	RPS12	-4.91239327478244	1.85340619742495e-09
KIRP	RPS24	RPL37	-1.17421621947139	2.26888805627823e-05
KIRC	RPS24	RPL35	-1.06475238059392	2.72286325678163e-08
KIRC	RPS24	RPL8	-1.18252459971773	5.64962994208288e-07
KIRP	RPS24	RPL8	-1.53003692350119	6.0301274061203e-05
KIRC	RPS24	RPS16	-1.66149869889384	7.8509870430991e-09
BRCA	RPS24	RPS27A	-4.28512148200424	7.8788217967112e-14
KIRC	RPS24	RPL37	-2.87198822058464	8.03913394748564e-12
KIRP	RPS24	RPL35	-1.52981101975496	9.0546440333128e-05
KIRC	RPS24	RPS3	-1.29560847926387	9.05905681935088e-10
KIRC	RPS24	RPL18A	-4.43079304960843	9.2516163152192e-11

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with RPS24

DCC, SIRT7, CUL3, CUL4B, CUL5, CUL2, CDK2, CUL1, COPS5, CAND1, RPL10A, RPL11, RPL12, RPL14, RPL30, RPL31, RPL6, RPS13, RPS14, RPS17, RPS3A, RPS3, RPS4X, RPS5, RPS6, RPS8, RPSA, RPL7, RPS7, RPL5, RPL18, RPL19, RPL18A, RPL7A, RPS15A, RPS23, RPL27, RPS11, RPL23, RPS16, RPS10, RPL10, RPS26, RPL4, RPL15, RPS19, RPLP2, RPL21, RPS2, RPL24, RPL23A, RPL37A, RPLP0, RPS12, RPL9, RPLP1, RPL22, RPL35, RPS9, RPS25, RPS15, RPL36, RPL3, RPS27A, RPL17, RPS21, RPL29, EEF2, EEF1A1, NCL, EIF3C, DDX21, ILF2, ILF3, NHP2L1, FBL, HNRNPU, HNRNPM, NOP58, NOP56, MYBBP1A, TUFM, U2AF1, DHX9, SLC25A5, U2AF2, GNL3, MOV10, EIF6, EIF4A3, RPLP0P6, RPL10L, SF3B6, MSH2, PRPF6, PSIP1, NFIA, RPS10P5, HP1BP3, PPP1CA, MOGS, RPS27L, NDUFAF2, NIFK, LOC255308, HIST1H2AD, PRPF19, ESR1, MAGOH, SMURF1, FN1, VCAM1, UBL4A, ITGA4, PAN2, PNISR, STK17B, PAH, PCBD1, TAF9, TARDBP, NUP188, PNO1, RPS18, RPS20, DYNC1H1, EIF2A, EIF3CL, FAU, PRUNE2, RPS28, RPS29, SERBP1, SPTAN1, WDR26, RPS27, TSR1, WIBG, TP53, HUWE1, EED, RNF2, RPL8, NPM1, Cbx1, Eif3a, Eif3e, Ktn1, Rpl35, Srp72, Rrbp1, Nup188, RC3H1, ZNF746, RRS1, E4F1, CYLD, TRIM25, BRCA1, FBXO7, HIF1AN, ACO2, CTNNB1, PYHIN1, PRPF8, AAR2, PIH1D1, EFTUD2, TNIP2, RNF4, CHD3, CHD4, TNF, HEXIM1, MEPCE, LARP7, SNAI1, AGR2, RECQL4, REST, ZFP36L2, MYC, RPS6KB2, EIF4B, RC3H2, ACTC1, PHB, USP14, NR2C2, PPP1CC, CTCF, VRK1, VRK3, DYRK1A, SNRNP70, Dppa3, ITFG1, HMGB1, IFT20, BIRC3, NFX1, WWP2, Dnajc17, SQSTM1, CMTR1, ARIH2, PLEKHA4, YAP1, TFCP2, FANCD2, HCVgp1, ZC3H18, MAP3K14, CCT7, SNIP1, E, M, nsp13, nsp14, nsp4, nsp5, nsp6, ORF3a, ORF6, ORF7a, ORF7b, S, ERCC6, NEK4, DUX4, CIT, ANLN, AURKB, CHMP4B, CHMP4C, ECT2, KIF14, KIF20A, KIF23, PRC1, C1QBP, NDN, BRD4, CIC, N, Apc2, RBM39, POU2F1, OGT, UFL1, DDRGK1, AATF, BBS7, BMS1, BOP1, BUD31, C18orf21, C8orf59, CAPRIN1, CCDC137, CCDC168, CCDC59, CEBPZ, CENPC, COIL, CTNNBL1, CXorf56, DDX10, DDX18, DDX24, DDX27, DDX31, DDX49, DDX50, DDX52, DDX54, DHX33, DHX37, DIEXF, DKC1, DNTTIP2, EBNA1BP2, EIF3B, EIF3J, ESF1, FAM207A, FAM32A, FTSJ3, GKAP1, GNL2, GNL3L, GTPBP4, H1FX, HEATR1, ISG20L2, KNOP1, KRI1, KRR1, LAS1L, LYAR, MAK16, MPHOSPH10, NAT10, NCAPD3, C3orf17, NGDN, NKRF, NOC2L, NOC3L, NOL10, NOL8, NOL9, NOLC1, NOM1, NOP14, NOP2, GLTSCR2, NUSAP1, PARN, PDCD11, PES1, PHF2, PINX1, PPAN-P2RY11, PPM1G, PSMD1, KIAA0020, PWP2, RALY, RBM19, RBM28, RBM34, REXO4, RIOK3, RNF10, RRP12, RRP15, RRP1B, RRP36, RRP7A, RRP8, RRP9, RSL1D1, SDAD1, SET, SPATS2L, SRFBP1, STRBP, SURF6, TBL3, TDRD3, TEX10, TXNL1, UBTF, UPF3B, URB1, URB2, USP36, UTP14A, UTP20, UTP3, WDR3, WDR36, WDR43, XRN2, ZC3H15, ZNF106, ZNF598, ANKRD11, ANP32E, ATAD5, BLM, BRIX1, CDCA8, CDK11A, DDX55, DDX56, EDF1, TCEB3, EXOSC10, FANCI, GPATCH4, GTF2F1, H2AFY, HNRNPDL, KIAA0368, LARP4B, MFAP1, MTDH, NUP205, NVL, PHF8, PRPF31, RPL13, SENP3, SND1, SUPT5H, TOP2B, ZNF644, nsp1, ATG10, ATG3, FZR1, PAGE4, NUDCD2, VPRBP, FGF13, RCBTB2, RPL26L1, HIST1H1A, NEURL4, MRPS18C, HERC2, PABPC4L, HIST1H1C, SRSF5, RGPD8, VANGL1, HIST1H1T, YBX1, TUBB3, ZCCHC9, DHX36, PHAX, SRSF1, ZNF346, LTV1, HIST1H1E, LIN28A, PRKRA, ZC3HAV1, NEIL1, RPSAP58, MAGEB2, MRPS26, HIST1H2AE, ZNF668, ZC3H3, SPRTN, BTF3, SLFN11, FBXW7, RCHY1, CCNF, NBR1, KLF12, CPEB1, GATA2, KLF4, TLX1,

Top

Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
RPS24	chr10	79789200	G	C	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Diamond-Blackfan_anemia\|Hypomyelinating_leukodystrophy_7	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS24	chr10	79789268	A	T	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Diamond-Blackfan_anemia\|Hypomyelinating_leukodystrophy_7\|Pol_III-related_leukodystrophy	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS24	chr10	79790159	TAACTCATTTCGGTACTCCATCACTTAATCATGAAATAATGTTGACTATATATATATATATATATATATATATATAGTCAACATTATGGGTTTTTTTTGTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCTAGACTGGAGTGCAGTGGCGAAATCTCGGCTCACCGCAACCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGGCTCAGCCTCCCGAGTAGCTGGGACTACAAGCGCCCGCC	T	Deletion	Pathogenic	Diamond-Blackfan_anemia_3
RPS24	chr10	79793518	A	G	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_3
RPS24	chr10	79793551	A	G	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_3\|Pol_III-related_leukodystrophy
RPS24	chr10	79793610	G	A	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia_3\|not_specified
RPS24	chr10	79793613	T	G	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_3
RPS24	chr10	79793623	C	T	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia_3	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS24	chr10	79793624	T	G	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_3	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS24	chr10	79793628	C	T	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_3	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS24	chr10	79793637	C	T	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia_3	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS24	chr10	79793652	T	G	single_nucleotide_variant	Benign/Likely_benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_3\|Pol_III-related_leukodystrophy\|not_specified	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS24	chr10	79793653	C	A	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_3	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS24	chr10	79793660	A	G	single_nucleotide_variant	Pathogenic	Diamond-Blackfan_anemia\|not_provided	SO:0001582\|initiatior_codon_variant,SO:0001583\|missense_variant	SO:0001582\|initiatior_codon_variant,SO:0001583\|missense_variant
RPS24	chr10	79793669	C	T	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Diamond-Blackfan_anemia_3\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79793671	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79793677	G	A	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia_3	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79793688	C	T	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_3	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79793877	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79793882	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79794821	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79795103	T	C	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_3	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79795110	AAC	TACGGATAG	Indel	Pathogenic	Diamond-Blackfan_anemia_3	SO:0001587\|nonsense	SO:0001587\|nonsense
RPS24	chr10	79795112	C	T	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia\|not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79795118	C	T	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79795118	CGT	C	Deletion	Pathogenic	Diamond-Blackfan_anemia	SO:0001589\|frameshift_variant	SO:0001589\|frameshift_variant
RPS24	chr10	79795126	T	G	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79795127	C	T	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79795152	C	T	single_nucleotide_variant	Pathogenic	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_3	SO:0001587\|nonsense	SO:0001587\|nonsense
RPS24	chr10	79795185	G	A	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79795259	C	T	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79795281	C	G	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79795281	C	T	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79795289	C	T	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79795290	G	A	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79795321	G	A	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79795347	A	C	single_nucleotide_variant	Pathogenic	Diamond-Blackfan_anemia_3	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79795354	CG	C	Deletion	Likely_pathogenic	Diamond-Blackfan_anemia_3	SO:0001589\|frameshift_variant	SO:0001589\|frameshift_variant
RPS24	chr10	79795364	C	T	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79795367	T	C	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_3	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79795373	T	G	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79795376	A	G	single_nucleotide_variant	Benign/Likely_benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_3\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79795388	T	C	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Diamond-Blackfan_anemia\|not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79795434	C	T	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_3	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79795445	A	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79795461	A	G	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79795475	A	T	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79795580	T	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79796676	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79796681	A	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79796726	G	C	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79796803	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79796900	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79796938	CTT	C	Deletion	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79796969	G	A	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79796978	C	T	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79796988	C	T	single_nucleotide_variant	Pathogenic	Diamond-Blackfan_anemia_3	SO:0001587\|nonsense	SO:0001587\|nonsense
RPS24	chr10	79796996	G	A	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79797005	G	A	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_3\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79797023	CAGG	C	Deletion	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001822\|inframe_deletion	SO:0001822\|inframe_deletion
RPS24	chr10	79797035	A	G	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79797043	A	G	single_nucleotide_variant	Benign/Likely_benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_3	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79797050	T	G	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79797527	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79797684	G	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79797690	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79797690	CCT	C	Microsatellite	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79798029	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79799719	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79799959	C	A	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_3\|not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79799975	G	A	single_nucleotide_variant	Likely_benign	not_specified\|not_provided	SO:0001624\|3_prime_UTR_variant,SO:0001627\|intron_variant	SO:0001624\|3_prime_UTR_variant,SO:0001627\|intron_variant
RPS24	chr10	79800043	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79800374	C	T	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_3	SO:0001583\|missense_variant,SO:0001624\|3_prime_UTR_variant,SO:0001627\|intron_variant	SO:0001583\|missense_variant,SO:0001624\|3_prime_UTR_variant,SO:0001627\|intron_variant
RPS24	chr10	79800452	T	C	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_3	SO:0001624\|3_prime_UTR_variant,SO:0001627\|intron_variant	SO:0001624\|3_prime_UTR_variant,SO:0001627\|intron_variant
RPS24	chr10	79814018	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS24	chr10	79814287	A	T	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001574\|splice_acceptor_variant	SO:0001574\|splice_acceptor_variant
RPS24	chr10	79814307	G	A	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_3	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79814319	T	C	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79814337	G	A	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_3	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79814370	G	T	single_nucleotide_variant	Likely_benign	not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79814404	AAGTGCCAGG	A	Deletion	Uncertain_significance	not_provided	SO:0001822\|inframe_deletion	SO:0001822\|inframe_deletion
RPS24	chr10	79814424	G	A	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79814557	C	T	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_3	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79814599	A	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79814697	C	G	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_3	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79814709	A	C	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_3	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79814718	G	T	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001587\|nonsense	SO:0001587\|nonsense
RPS24	chr10	79814726	C	A	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia_3	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS24	chr10	79814747	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS24	chr10	79814868	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001624\|3_prime_UTR_variant	SO:0001624\|3_prime_UTR_variant
RPS24	chr10	79814973	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001624\|3_prime_UTR_variant	SO:0001624\|3_prime_UTR_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
RPS24	UCEC	chr10	79797001	79797001	G	A	Missense_Mutation	p.R110H	4
RPS24	KIRP	chr10	79796974	79796974	A	G	Missense_Mutation	p.K101R	3
RPS24	ACC	chr10	79814544	79814544	G	T	Missense_Mutation	p.V216F	3
RPS24	ESCA	chr10	79814587	79814587	C	A	Missense_Mutation	p.A230D	3
RPS24	ESCA	chr10	79814587	79814587	C	A	Missense_Mutation		2
RPS24	SKCM	chr10	79795386	79795386	C	T	Missense_Mutation	p.H63Y	2
RPS24	STAD	chr10	79795304	79795304	G	A	Silent	p.V35V	2
RPS24	CHOL	chr10	79814760	79814760	G	T	Missense_Mutation		2
RPS24	STAD	chr10	79795119	79795119	G	A	Missense_Mutation	p.V5I	2
RPS24	CHOL	chr10	79814760	79814760	G	T	Missense_Mutation	p.G288C	2
RPS24	KIRP	chr10	79795290	79795290	G	T	Missense_Mutation		2
RPS24	LGG	chr10	79793660	79793660	A	C	Missense_Mutation	p.M1L	2
RPS24	CESC	chr10	79814352	79814352	G	C	Missense_Mutation		2
RPS24	CESC	chr10	79814352	79814352	G	C	Missense_Mutation	p.D152H	1
RPS24	HNSC	chr10	79797023	79797023	C	T	Silent		1
RPS24	HNSC	chr10	79797023	79797023	C	T	Missense_Mutation	p.117_117insV	1
RPS24	UCEC	chr10	79797042	79797042	A	G	Missense_Mutation	p.N124D	1
RPS24	COAD	chr10	79795341	79795341	T	A	Missense_Mutation	p.Y48N	1
RPS24	COAD	chr10	79814360	79814360	G	T	Missense_Mutation	p.K154N	1
RPS24	COAD	chr10	79814433	79814433	T	C	Missense_Mutation	p.C179R	1
RPS24	LIHC	chr10	79799959	79799959	C	A	Missense_Mutation		1
RPS24	DLBC	chr10	79814747	79814747	C	T	Silent	p.C283C	1
RPS24	LIHC	chr10	79795311	79795311	A	G	Missense_Mutation	p.T38A	1
RPS24	DLBC	chr10	79814612	79814612	T	C	Silent	p.G238G	1
RPS24	LIHC	chr10	79814383	79814383	G	-	Frame_Shift_Del	p.R162fs	1
RPS24	BLCA	chr10	79795399	79795399	G	T	Missense_Mutation	p.G67V	1
RPS24	ESCA	chr10	79793751	79793751	G	T	RNA	NULL	1
RPS24	PAAD	chr10	79796976	79796976	A	G	Missense_Mutation	p.T102A	1
RPS24	CESC	chr10	79795109	79795109	G	T	Splice_Site		1
RPS24	READ	chr10	79814326	79814326	G	T	Missense_Mutation	p.R143I	1

Copy number variation (CNV) of RPS24
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across RPS24
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
83858	COAD	TCGA-AA-A01T-01A	ALDH2	chr12	112221075	+	RPS24	chr10	79796997	+
83858	N/A	CD240395	CELF2	chr10	11282989	-	RPS24	chr10	79795312	+
83858	N/A	EC557899	DGCR5	chr22	18968969	+	RPS24	chr10	79795449	+
83858	N/A	AA654530	FARS2	chr6	5580193	+	RPS24	chr10	79800454	-
83858	N/A	BE771787	FLVCR2	chr14	76062459	+	RPS24	chr10	79797057	-
83858	N/A	EC500048	FOXP2	chr7	113732220	+	RPS24	chr10	79800453	-
83858	N/A	BU153261	IDH1	chr2	209104672	-	RPS24	chr10	79795397	+
83858	N/A	BG621223	PAPPA	chr9	119140236	+	RPS24	chr10	79797017	+
83858	N/A	EC583298	PCDH15	chr10	55598499	-	RPS24	chr10	79800449	-
83858	Non-Cancer	43N	PSAP	chr10	73610938	-	RPS24	chr10	79795109	+
83858	BRCA	TCGA-OL-A5RZ-01A	RPL19	chr17	37359365	+	RPS24	chr10	79800367	+
83858	N/A	EC464784	RPL37A	chr2	217363601	+	RPS24	chr10	79796952	+
83858	N/A	AI908980	RPS23	chr5	81573514	-	RPS24	chr10	79799960	+
91137	OV	TCGA-09-1670	RPS24	chr10	79797062	+	CAT	chr11	34473623	+
102228	N/A	AF091518	RPS24	chr10	79795349	+	CFL1	chr11	65622663	-
102746	N/A	BQ027949	RPS24	chr10	79795400	-	CLASP1	chr2	122122756	+
100477	N/A	AI810209	RPS24	chr10	79797031	-	CLSTN2	chr3	139768442	-
99198	N/A	BF215585	RPS24	chr10	79800450	+	CSMD1	chr8	3128460	-
100831	N/A	AA535098	RPS24	chr10	79797005	-	CTNND1	chr11	57575966	-
100880	N/A	GW492978	RPS24	chr10	79800459	+	DIXDC1	chr11	111803093	+
84313	N/A	AW838567	RPS24	chr10	79797006	+	DNAJC2	chr7	102963201	-
99661	N/A	EC440463	RPS24	chr10	79800371	-	FAM161A	chr2	62030612	-
77693	N/A	EC453455	RPS24	chr10	79800373	-	FLVCR2	chr14	76062135	+
101442	N/A	EC447612	RPS24	chr10	79800453	+	FOXP2	chr7	113732220	-
92750	N/A	AI818425	RPS24	chr10	79795268	-	GPC3	chrX	132805330	-
100520	N/A	AV682610	RPS24	chr10	79800452	+	GPHN	chr14	68180107	+
77693	N/A	AV681799	RPS24	chr10	79800455	+	HIBCH	chr2	191124295	-
97523	STAD	TCGA-BR-8678-01A	RPS24	chr10	79797062	+	HSPG2	chr1	22192302	-
77693	N/A	BE738166	RPS24	chr10	79800453	+	ITM2A	chrX	78616239	+
97947	N/A	BG489521	RPS24	chr10	79800399	+	LUZP1	chr1	23420874	-
77693	N/A	BE737902	RPS24	chr10	79800450	+	MPV17L	chr16	15506621	-
101088	N/A	BP431781	RPS24	chr10	79797062	+	NFATC3	chr16	68160254	+
90464	N/A	BG574861	RPS24	chr10	79800455	+	NR2C2	chr3	15081665	+
95663	N/A	BG033843	RPS24	chr10	79800455	+	PPP6R2	chr22	50793969	-
94587	N/A	BG032925	RPS24	chr10	79800455	+	RNASEH2B	chr13	51546623	+
77693	N/A	AV685731	RPS24	chr10	79800455	+	RP4-771M4.3	chr1	63361988	-
83858	N/A	AA730779	RPS24	chr10	79800437	+	RPS24	chr10	79797047	-
83858	N/A	AW130504	RPS24	chr10	79800107	-	RPS24	chr10	79800088	+
93962	N/A	AV699197	RPS24	chr10	79800455	+	TBC1D15	chr12	72270592	-
83858	N/A	M31520	RPS27	chr1	153964127	-	RPS24	chr10	79793623	+
83861	N/A	BG287995	SMAP2	chr1	40882755	+	RPS24	chr10	79800389	+

Top

Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

Top

Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
SARC	RPS24	0.00298596622408238	0.084
MESO	RPS24	0.0071505961093859	0.19
KIRC	RPS24	0.0291313257223093	0.76

Top

Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
STAD	RPS24	0.0335939551784547	0.97
LUSC	RPS24	0.0254569368241553	0.76
GBM	RPS24	0.041823947184901	1
LGG	RPS24	0.0339773313350301	0.97
LAML	RPS24	0.0235943433228183	0.73
BRCA	RPS24	0.0129074023396721	0.43
PAAD	RPS24	0.013981486484011	0.45

Top

Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C1260899	Anemia, Diamond-Blackfan	8	CLINGEN;GENOMICS_ENGLAND
C0265265	Aase syndrome	6	CLINGEN
C1857719	Anemia, Diamond-Blackfan, 3	5	CTD_human;GENOMICS_ENGLAND
C2931850	Aase Smith syndrome 2	1	GENOMICS_ENGLAND