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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: CNBP (NCBI Gene ID:7555)

Gene Summary

Gene Summary

Gene Information	Gene Name: CNBP
	Gene ID: 7555
	Gene Symbol	CNBP
	Gene ID	7555
	Gene Name	CCHC-type zinc finger nucleic acid binding protein
	Synonyms	CNBP1\|DM2\|PROMM\|RNF163\|ZCCHC22\|ZNF9
	Cytomap	3q21.3
	Type of Gene	protein-coding
	Description	cellular nucleic acid-binding proteinerythroid differentiation-relatedsterol regulatory element-binding proteinzinc finger protein 273zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)
	Modification date	20200328
	UniProtAcc	P62633

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0006417	Regulation of translation
GO:0045727	Positive regulation of translation
GO:0002181	Cytoplasmic translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	CNBP	GO:0000122	negative regulation of transcription by RNA polymerase II	23774591

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
CNBP	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'CNBP[title] AND translation [title] AND human.'

Gene	Title	PMID
CNBP	CNBP regulates wing development in Drosophila melanogaster by promoting IRES-dependent translation of dMyc	24275942

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000422453	128890476	128890614	3UTR-3CDS

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
UCEC	CNBP	-3.53819793407721	0.03125
KIRP	CNBP	1.28844039621419	1.42422504723072e-05

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type	Gene	miRNA	TargetScan binding score (Context++ score percentile)	Coefficient	Pvalue
UCEC	CNBP	hsa-miR-369-3p	98	0.440794499618029	0.00964621172762361

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
OV	CNBP	0.136533633	0.021099076

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with CNBP (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
KICH	Epifactor	CNBP	MBD4	0.800276231	1.79E-21
KICH	IUPHAR	CNBP	CRBN	0.802129268	1.23E-21
KICH	TF	CNBP	MBD4	0.800276231	1.79E-21
KICH	TSG	CNBP	MBD4	0.800276231	1.79E-21
UVM	Cell metabolism gene	CNBP	B4GALT4	0.801960805	3.93E-19
UVM	Cell metabolism gene	CNBP	DNAJC19	0.818168974	1.96E-20
UVM	Cell metabolism gene	CNBP	METTL6	0.832847785	9.88E-22
UVM	Cell metabolism gene	CNBP	PSMD6	0.838831057	2.69E-22
UVM	Cell metabolism gene	CNBP	DCP1A	0.849762759	2.16E-23
UVM	Cell metabolism gene	CNBP	TOMM70A	0.895637984	3.60E-29
UVM	CGC	CNBP	ATR	0.811540313	6.92E-20
UVM	CGC	CNBP	MLF1	0.816982309	2.46E-20
UVM	CGC	CNBP	SETD2	0.867291067	2.43E-25
UVM	Epifactor	CNBP	RNF8	0.801521173	4.25E-19
UVM	Epifactor	CNBP	SETD5	0.804949307	2.31E-19
UVM	Epifactor	CNBP	ATR	0.811540313	6.92E-20
UVM	Epifactor	CNBP	PHC3	0.822883264	7.73E-21
UVM	Epifactor	CNBP	TOP2B	0.826383996	3.81E-21
UVM	Epifactor	CNBP	HLTF	0.834237579	7.34E-22
UVM	Epifactor	CNBP	RNF2	0.839304552	2.42E-22
UVM	Epifactor	CNBP	ATXN7	0.845739484	5.59E-23
UVM	Epifactor	CNBP	RYBP	0.84963052	2.23E-23
UVM	Epifactor	CNBP	MINA	0.849782195	2.15E-23
UVM	Epifactor	CNBP	UBE2E1	0.853888546	7.93E-24
UVM	Epifactor	CNBP	ACTL6A	0.859508195	1.92E-24
UVM	Epifactor	CNBP	SETD2	0.867291067	2.43E-25
UVM	Epifactor	CNBP	MSL2	0.901125787	4.88E-30
UVM	Epifactor	CNBP	MBD4	0.908277146	3.00E-31
UVM	IUPHAR	CNBP	ATR	0.811540313	6.92E-20
UVM	IUPHAR	CNBP	ATP2C1	0.826500171	3.72E-21
UVM	IUPHAR	CNBP	CRBN	0.834911653	6.35E-22
UVM	IUPHAR	CNBP	SNRK	0.835363265	5.75E-22
UVM	IUPHAR	CNBP	SLC25A36	0.835364736	5.75E-22
UVM	IUPHAR	CNBP	RYK	0.836219788	4.78E-22
UVM	IUPHAR	CNBP	PRKCI	0.848377257	3.01E-23
UVM	IUPHAR	CNBP	ATP13A3	0.861934075	1.02E-24
UVM	IUPHAR	CNBP	OXSR1	0.863189294	7.33E-25
UVM	IUPHAR	CNBP	ACVR2B	0.864479197	5.20E-25
UVM	IUPHAR	CNBP	SETD2	0.867291067	2.43E-25
UVM	IUPHAR	CNBP	SLC35A5	0.876791829	1.61E-26
UVM	Kinase	CNBP	ATR	0.811540313	6.92E-20
UVM	Kinase	CNBP	SNRK	0.835363265	5.75E-22
UVM	Kinase	CNBP	RYK	0.836219788	4.78E-22
UVM	Kinase	CNBP	PRKCI	0.848377257	3.01E-23
UVM	Kinase	CNBP	OXSR1	0.863189294	7.33E-25
UVM	Kinase	CNBP	ACVR2B	0.864479197	5.20E-25
UVM	TF	CNBP	ZBTB11	0.804239449	2.62E-19
UVM	TF	CNBP	ZNF525	0.805112928	2.24E-19
UVM	TF	CNBP	ZBTB38	0.812216244	6.09E-20
UVM	TF	CNBP	BBX	0.817866256	2.08E-20
UVM	TF	CNBP	ZNF621	0.858179304	2.70E-24
UVM	TF	CNBP	CGGBP1	0.862530998	8.73E-25
UVM	TF	CNBP	UBP1	0.872305269	5.96E-26
UVM	TF	CNBP	ZNF639	0.892126817	1.22E-28
UVM	TF	CNBP	ZNF197	0.905670817	8.50E-31
UVM	TF	CNBP	MBD4	0.908277146	3.00E-31
UVM	TSG	CNBP	EAF1	0.80097297	4.68E-19
UVM	TSG	CNBP	RNF8	0.801521173	4.25E-19
UVM	TSG	CNBP	ATR	0.811540313	6.92E-20
UVM	TSG	CNBP	PHC3	0.822883264	7.73E-21
UVM	TSG	CNBP	HLTF	0.834237579	7.34E-22
UVM	TSG	CNBP	WDR48	0.85228241	1.18E-23
UVM	TSG	CNBP	SETD2	0.867291067	2.43E-25
UVM	TSG	CNBP	MBD4	0.908277146	3.00E-31

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
THCA	CNBP	HSPA9	1.4370008925461	0.000619324585728192
THCA	CNBP	DMPK	1.55371002259454	0.000672964057081266
BRCA	CNBP	PCBP2	-1.83222008154583	0.000732095066837025
STAD	CNBP	MBNL1	-1.68295845052622	0.00166679499670863
COAD	CNBP	PCBP2	-3.87878167210665	0.0021815299987793
KIRP	CNBP	PCBP2	-1.03595774862204	0.00571200484409928
PRAD	CNBP	PCBP2	-1.22915710157917	0.00712181487955485
CHOL	CNBP	MBNL3	-3.38335295377879	0.0078125
THCA	CNBP	HNRNPK	-8.73422542563389	0.00797530353045887
PRAD	CNBP	MBNL3	-2.69203314169504	0.0098283424925592
CHOL	CNBP	HSPA9	-2.62699011232753	0.01171875
KIRP	CNBP	MBNL1	-1.16300195475505	0.0118026207201183
LIHC	CNBP	PCBP2	-1.54798507591199	0.0120781615488378
CHOL	CNBP	MBNL2	-3.48065116982808	0.02734375
UCEC	CNBP	HNRNPK	1.64532744504864	0.03125
READ	CNBP	MBNL3	-3.37045285809744	0.03125
BLCA	CNBP	PCBP2	-3.89198758435569	0.0323410034179688
KIRP	CNBP	MBNL3	-1.24156302960915	0.0375871751457453
LIHC	CNBP	MBNL2	-3.28826451458899	1.03660595360911e-06
PRAD	CNBP	DMPK	-2.24762210601826	1.07311825696129e-07
BRCA	CNBP	MBNL1	-3.98550727765246	1.08293518653207e-22
LUSC	CNBP	MBNL1	-1.10522358956529	1.38150619305268e-08
LUAD	CNBP	HSPA9	-2.37166542508773	2.1660933617938e-09
BRCA	CNBP	EIF4B	-2.16032742029696	2.35556737304054e-22
LUSC	CNBP	HSPA9	-2.24373536125322	2.51071930113563e-08
BRCA	CNBP	MBNL2	-2.61596782131201	3.64562360701576e-24
KIRC	CNBP	MBNL3	-1.28224297055762	4.47117775598177e-07
BLCA	CNBP	DMPK	-2.76421996936472	5.340576171875e-05
LUAD	CNBP	MBNL2	-1.22470716607101	6.36796101058976e-06
KIRC	CNBP	EIF4B	1.14997140510474	7.59366366705366e-09
KICH	CNBP	HSPA9	1.92562580260863	8.34465026855468e-07

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with CNBP

IGF2BP1, RPL3, HNRNPC, PURA, RPS3A, DHX9, HNRNPAB, RPL34, IGF2BP3, BRIX1, RPL23A, RBMX, HNRNPR, RPL31, RPL35A, RPS16, APOBEC3C, RPA3, RPL36, RPS19, ERH, EBNA1BP2, HNRNPUL1, SYNCRIP, HNRNPA3, RSL1D1, DAP3, FKTN, MYH4, ZWINT, Cnbp, Mis12, KCND3, VCAM1, ITGA4, PAN2, MAPK14, BZW2, DFFA, EIF6, FERMT2, HSPA9, PFAS, EZH2, SUZ12, RNF2, BMI1, CDK2, MARK3, WEE1, CADM1, HK2, NMD3, PABPC3, PABPC4, CASP8, HIST1H3E, EGFR, TRIM56, HIST1H1A, NLE1, ZNF275, ITGB3BP, RPL18, RPF2, RPL26L1, DDX31, RPLP0, RPL27, GTPBP4, RPLP2, GNL2, ZC3HAV1, RPF1, RPL4, RPL10A, RPL18A, KIAA0020, ZNF689, STAU1, RPL32, RPS8, CENPN, RPL37A, PAK1IP1, RPL13, RPL14, RRS1, RPL15, CENPU, ZNF184, WHSC1, ZNF800, RPL12, GLYR1, RPS6, RSL24D1, RRP8, RPL6, TTF1, ZFP62, ZNF512, DDX27, REPIN1, RPLP1, ZNF48, RPL30, RPL7, RPS13, RPL8, C8orf33, NSA2, RBM34, ZSCAN25, DDX24, SURF6, FTSJ3, NIP7, RPL11, DKC1, RPL5, PPAN-P2RY11, NOL12, NOP56, POP1, NOP2, DHX30, DDX21, FCF1, RPL7A, MAK16, RPL13A, RBM28, RPL7L1, LLPH, PAPD5, ABT1, ZNF771, GLTSCR2, CCDC137, NR3C1, AR, ARNT, EFTUD2, RNF31, ESR2, HEXIM1, MEPCE, LARP7, VCP, RAB11A, BET1, CDK7, DYRK1A, LRRK2, PLEKHA4, NGB, NHLRC2, HCVgp1, RAB5A, ESR1, HRH1, KIF23, Arhgap1, DOCK9, CDC42, PTEN, Apc2, FBP1, nsp14, BRD1, KDM4C, ING4, ING5, MEAF6, KDM4D, SMCHD1, KAT7, ERP44, KAT6B, IDH2, HOMER1, DDX58, TRIM37, WDR5, NIFK, RPL26, RPL17, ZNF22, CCDC86, HIST1H2AG, YBX3, NKRF, C7orf50, FYTTD1, HP1BP3, RPS9, BTF3, ORF10, ORF8, NRP1, TMPRSS2, TOP3B, CTSL, FURIN, IFITM1, DPP4, IFITM3, TMPRSS11B, CLEC4D, ACE2, CLEC4E, E, nsp2, nsp4, ORF3a, ORF6, S, CCNF, KLF10, KLF3, KLF6, KLF9,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
CNBP	chr3	128890350	G	A	single_nucleotide_variant	Benign	Myotonic_dystrophy_type_2\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
CNBP	chr3	128890540	T	C	single_nucleotide_variant	Uncertain_significance	Myotonic_dystrophy_type_2	SO:0001583\|missense_variant	SO:0001583\|missense_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
CNBP	KIRC	chr3	128890023	128890023	G	A	Silent	p.G105G	4
CNBP	PAAD	chr3	128890615	128890615	C	A	Splice_Site		3
CNBP	PAAD	chr3	128889940	128889940	G	A	Missense_Mutation	p.T133I	2
CNBP	PAAD	chr3	128890570	128890570	G	A	Nonsense_Mutation	p.R11*	2
CNBP	UCEC	chr3	128889344	128889344	G	A	Silent	p.G164	2
CNBP	UCEC	chr3	128889962	128889962	C	T	Missense_Mutation	p.G128R	2
CNBP	PAAD	chr3	128889940	128889940	G	A	Missense_Mutation		2
CNBP	LGG	chr3	128889325	128889325	G	A	Missense_Mutation	p.R169W	2
CNBP	UCEC	chr3	128890058	128890058	G	A	Nonsense_Mutation	p.R96*	2
CNBP	UCEC	chr3	128890121	128890121	C	A	Splice_Site	e3-1	2
CNBP	LGG	chr3	128890339	128890339	C	T	Missense_Mutation		1
CNBP	PAAD	chr3	128889940	128889940	G	A	Missense_Mutation	p.T135I	1
CNBP	CESC	chr3	128902672	128902672	A	C	Missense_Mutation		1
CNBP	STAD	chr3	128890519	128890519	C	A	Nonsense_Mutation	p.G28X	1
CNBP	LIHC	chr3	128889330	128889330	A	G	Missense_Mutation		1
CNBP	COAD	chr3	128890099	128890099	C	T	Missense_Mutation	p.G81D	1
CNBP	STAD	chr3	128890519	128890519	C	A	Nonsense_Mutation	p.G28*	1
CNBP	LIHC	chr3	128889414	128889414	C	T	Splice_Site	.	1
CNBP	ESCA	chr3	128889387	128889387	A	G	Missense_Mutation	p.I150T	1
CNBP	TGCT	chr3	128889947	128889948	-	-	Frame_Shift_Ins		1
CNBP	LIHC	chr3	128890513	128890513	T	A	Nonsense_Mutation	p.R30X	1
CNBP	PAAD	chr3	128890570	128890570	G	A	Nonsense_Mutation		1
CNBP	ESCA	chr3	128890058	128890058	G	A	Nonsense_Mutation	p.R96X	1
CNBP	TGCT	chr3	128889947	128889948	-	T	Frame_Shift_Ins	p.D133fs	1
CNBP	LIHC	chr3	128890513	128890513	T	A	Nonsense_Mutation	p.R30*	1
CNBP	PRAD	chr3	128890476	128890476	C	A	Splice_Site		1
CNBP	ESCA	chr3	128890490	128890490	A	-	Frame_Shift_Del	p.F37fs	1
CNBP	TGCT	chr3	128889947	128889948	-	T	Frame_Shift_Ins	p.L131fs	1
CNBP	LIHC	chr3	128890513	128890513	T	A	Missense_Mutation		1
CNBP	READ	chr3	128890005	128890005	G	A	Silent	p.C112C	1
CNBP	HNSC	chr3	128889324	128889324	C	A	Missense_Mutation		1
CNBP	UCEC	chr3	128889318	128889318	C	A	Missense_Mutation	p.C173F	1
CNBP	LUAD	chr3	128889925	128889925	T	C	Missense_Mutation	p.Y138C	1
CNBP	SKCM	chr3	128889945	128889945	G	A	Silent	p.D132D	1
CNBP	KIRC	chr3	128890023	128890023	G	A	Silent	p.G107G	1
CNBP	LUSC	chr3	128890383	128890383	T	C	Splice_Site	p.G42_splice	1
CNBP	ACC	chr3	128889366	128889366	T	C	Missense_Mutation	p.E157G	1
CNBP	SKCM	chr3	128889945	128889945	G	A	Silent	p.D131D	1
CNBP	ACC	chr3	128889366	128889366	T	C	Missense_Mutation	p.E156G	1
CNBP	SKCM	chr3	128890366	128890366	G	A	Missense_Mutation	p.S47F	1
CNBP	BLCA	chr3	128889334	128889334	G	T	Missense_Mutation		1
CNBP	SKCM	chr3	128890001	128890001	G	A	Missense_Mutation	p.H113Y	1
CNBP	LGG	chr3	128890339	128890339	C	T	Missense_Mutation	p.R56H	1
CNBP	PAAD	chr3	128890615	128890615	C	A	Splice_Site	.	1
CNBP	BLCA	chr3	128889334	128889334	G	T	Missense_Mutation	p.H166N	1
CNBP	STAD	chr3	128890121	128890121	C	T	Missense_Mutation	p.A75T	1

Copy number variation (CNV) of CNBP
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across CNBP
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
102978	STAD	TCGA-FP-8209-01A	ABR	chr17	982570	-	CNBP	chr3	128890614	-
102978	N/A	AV733123	ATP1A3	chr19	42474365	+	CNBP	chr3	128889023	-
91364	LGG	TCGA-HT-7858-01A	CNBP	chr3	128902619	-	ALDH1L1	chr3	125831723	-
101911	N/A	BG149780	CNBP	chr3	128887013	+	CSNK2A1	chr20	523424	+
82238	N/A	BI856841	CNBP	chr3	128888451	-	LACE1	chr6	108785808	+
99955	Non-Cancer	TCGA-HU-A4GP-11A	CNBP	chr3	128902619	-	LRCH3	chr3	197574280	+
90724	STAD	TCGA-EQ-A4SO-01A	CNBP	chr3	128902619	-	RPN1	chr3	128341252	-
102785	STAD	TCGA-BR-A4PD	CNBP	chr3	128902618	-	SMARCB1	chr22	24175758	+
102785	STAD	TCGA-BR-A4PD-01A	CNBP	chr3	128902619	-	SMARCB1	chr22	24175759	+
17624	ESCA	TCGA-LN-A49R	CNBP	chr3	128902619	-	UNC93B6	chr11	71318338	+
17624	ESCA	TCGA-LN-A49R-01A	CNBP	chr3	128902619	-	UNC93B6	chr11	71316395	+
90735	aneurysmal bone cyst	AY624556	CNBP	chr3	128902727		USP6	chr17	5033660
90735	.	.	CNBP	chr3	128902618	-	USP6	chr17	5031686	+
90735	.	.	CNBP	chr3	128902618	-	USP6	chr17	5033661	+
90735	N/A	AY624556	CNBP	chr3	128902618	-	USP6	chr17	5033660	+
90735	N/A	AY624557	CNBP	chr3	128902618	-	USP6	chr17	5033229	+
102978	BLCA	TCGA-DK-A2I1-01A	FBLN1	chr22	45898944	+	CNBP	chr3	128890614	-
102978	N/A	AW796677	NAP1L4	chr11	3003185	-	CNBP	chr3	128888575	-
102978	STAD	TCGA-HU-A4GY	TBL1XR1	chr3	176914908	-	CNBP	chr3	128890614	-
102978	N/A	BM150482	ZBTB38	chr3	141106446	-	CNBP	chr3	128888420	+
102982	STAD	TCGA-BR-A4PD	ZNF7	chr8	146054989	+	CNBP	chr3	128890614	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
TGCT	CNBP	0.000378571492598778	0.011

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
TGCT	CNBP	0.00199425429452273	0.064
KIRP	CNBP	0.0487312997125138	1
ESCA	CNBP	6.03042097766637e-06	2e-04
THYM	CNBP	0.0172151382778225	0.53

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C2931689	Dystrophia myotonica 2	1	CTD_human;GENOMICS_ENGLAND