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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:YLPM1-EPHB6 (FusionGDB2 ID:100034)

Fusion Gene Summary for YLPM1-EPHB6

check button Fusion gene summary
Fusion gene informationFusion gene name: YLPM1-EPHB6
Fusion gene ID: 100034
HgeneTgene
Gene symbol

YLPM1

EPHB6

Gene ID

56252

2051

Gene nameYLP motif containing 1EPH receptor B6
SynonymsC14orf170|PPP1R169|ZAP113|ZAP3HEP
Cytomap

14q24.3

7q34

Type of geneprotein-codingprotein-coding
DescriptionYLP motif-containing protein 1nuclear protein ZAP3protein phosphatase 1, regulatory subunit 169ephrin type-B receptor 6human kinase-defective Eph-family receptor proteintyrosine-protein kinase-defective receptor EPH-6
Modification date2020031320200320
UniProtAcc.

O15197

Ensembl transtripts involved in fusion geneENST00000238571, ENST00000325680, 
ENST00000546901, ENST00000552421, 
ENST00000476059, ENST00000392957, 
ENST00000411471, ENST00000442129, 
Fusion gene scores* DoF score7 X 10 X 3=2102 X 2 X 1=4
# samples 102
** MAII scorelog2(10/210*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/4*10)=2.32192809488736
Context

PubMed: YLPM1 [Title/Abstract] AND EPHB6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointYLPM1(75265473)-EPHB6(142568562), # samples:2
EPHB6(142568562)-YLPM1(75265473), # samples:1
Anticipated loss of major functional domain due to fusion event.EPHB6-YLPM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
EPHB6-YLPM1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
EPHB6-YLPM1 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
EPHB6-YLPM1 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
EPHB6-YLPM1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across YLPM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EPHB6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AAK091050YLPM1chr14

75265473

+EPHB6chr7

142568562

+
ChiTaRS5.0N/AAX746751YLPM1chr14

75265473

+EPHB6chr7

142568562

+


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Fusion Gene ORF analysis for YLPM1-EPHB6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000238571ENST00000476059YLPM1chr14

75265473

+EPHB6chr7

142568562

+
5CDS-3UTRENST00000325680ENST00000476059YLPM1chr14

75265473

+EPHB6chr7

142568562

+
In-frameENST00000238571ENST00000392957YLPM1chr14

75265473

+EPHB6chr7

142568562

+
In-frameENST00000238571ENST00000411471YLPM1chr14

75265473

+EPHB6chr7

142568562

+
In-frameENST00000238571ENST00000442129YLPM1chr14

75265473

+EPHB6chr7

142568562

+
In-frameENST00000325680ENST00000392957YLPM1chr14

75265473

+EPHB6chr7

142568562

+
In-frameENST00000325680ENST00000411471YLPM1chr14

75265473

+EPHB6chr7

142568562

+
In-frameENST00000325680ENST00000442129YLPM1chr14

75265473

+EPHB6chr7

142568562

+
intron-3CDSENST00000546901ENST00000392957YLPM1chr14

75265473

+EPHB6chr7

142568562

+
intron-3CDSENST00000546901ENST00000411471YLPM1chr14

75265473

+EPHB6chr7

142568562

+
intron-3CDSENST00000546901ENST00000442129YLPM1chr14

75265473

+EPHB6chr7

142568562

+
intron-3CDSENST00000552421ENST00000392957YLPM1chr14

75265473

+EPHB6chr7

142568562

+
intron-3CDSENST00000552421ENST00000411471YLPM1chr14

75265473

+EPHB6chr7

142568562

+
intron-3CDSENST00000552421ENST00000442129YLPM1chr14

75265473

+EPHB6chr7

142568562

+
intron-3UTRENST00000546901ENST00000476059YLPM1chr14

75265473

+EPHB6chr7

142568562

+
intron-3UTRENST00000552421ENST00000476059YLPM1chr14

75265473

+EPHB6chr7

142568562

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000238571YLPM1chr1475265473+ENST00000392957EPHB6chr7142568562+303327481242904926
ENST00000238571YLPM1chr1475265473+ENST00000442129EPHB6chr7142568562+303327481242904926
ENST00000238571YLPM1chr1475265473+ENST00000411471EPHB6chr7142568562+303327481242904926
ENST00000325680YLPM1chr1475265473+ENST00000392957EPHB6chr7142568562+3618333312434891121
ENST00000325680YLPM1chr1475265473+ENST00000442129EPHB6chr7142568562+3618333312434891121
ENST00000325680YLPM1chr1475265473+ENST00000411471EPHB6chr7142568562+3618333312434891121

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000238571ENST00000392957YLPM1chr1475265473+EPHB6chr7142568562+0.0090900910.9909099
ENST00000238571ENST00000442129YLPM1chr1475265473+EPHB6chr7142568562+0.0090900910.9909099
ENST00000238571ENST00000411471YLPM1chr1475265473+EPHB6chr7142568562+0.0090900910.9909099
ENST00000325680ENST00000392957YLPM1chr1475265473+EPHB6chr7142568562+0.0059063410.9940937
ENST00000325680ENST00000442129YLPM1chr1475265473+EPHB6chr7142568562+0.0059063410.9940937
ENST00000325680ENST00000411471YLPM1chr1475265473+EPHB6chr7142568562+0.0059063410.9940937

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Fusion Genomic Features for YLPM1-EPHB6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for YLPM1-EPHB6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:75265473/chr7:142568562)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EPHB6

O15197

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2. {ECO:0000269|PubMed:12517763, ECO:0000269|PubMed:15955811}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEPHB6chr14:75265473chr7:142568562ENST00000392957020166_17601022.0Compositional biasNote=Poly-Ser
TgeneEPHB6chr14:75265473chr7:142568562ENST00000392957020219_36601022.0Compositional biasNote=Cys-rich
TgeneEPHB6chr14:75265473chr7:142568562ENST00000392957020881_88401022.0Compositional biasNote=Poly-Pro
TgeneEPHB6chr14:75265473chr7:142568562ENST00000442129020166_17601022.0Compositional biasNote=Poly-Ser
TgeneEPHB6chr14:75265473chr7:142568562ENST00000442129020219_36601022.0Compositional biasNote=Cys-rich
TgeneEPHB6chr14:75265473chr7:142568562ENST00000442129020881_88401022.0Compositional biasNote=Poly-Pro
TgeneEPHB6chr14:75265473chr7:142568562ENST0000039295702033_23701022.0DomainEph LBD
TgeneEPHB6chr14:75265473chr7:142568562ENST00000392957020369_48601022.0DomainFibronectin type-III 1
TgeneEPHB6chr14:75265473chr7:142568562ENST00000392957020487_58201022.0DomainFibronectin type-III 2
TgeneEPHB6chr14:75265473chr7:142568562ENST00000392957020670_91901022.0DomainProtein kinase
TgeneEPHB6chr14:75265473chr7:142568562ENST00000392957020948_101201022.0DomainSAM
TgeneEPHB6chr14:75265473chr7:142568562ENST0000044212902033_23701022.0DomainEph LBD
TgeneEPHB6chr14:75265473chr7:142568562ENST00000442129020369_48601022.0DomainFibronectin type-III 1
TgeneEPHB6chr14:75265473chr7:142568562ENST00000442129020487_58201022.0DomainFibronectin type-III 2
TgeneEPHB6chr14:75265473chr7:142568562ENST00000442129020670_91901022.0DomainProtein kinase
TgeneEPHB6chr14:75265473chr7:142568562ENST00000442129020948_101201022.0DomainSAM
TgeneEPHB6chr14:75265473chr7:142568562ENST000003929570201019_102101022.0MotifPDZ-binding
TgeneEPHB6chr14:75265473chr7:142568562ENST000004421290201019_102101022.0MotifPDZ-binding
TgeneEPHB6chr14:75265473chr7:142568562ENST00000392957020676_68401022.0Nucleotide bindingATP
TgeneEPHB6chr14:75265473chr7:142568562ENST00000442129020676_68401022.0Nucleotide bindingATP
TgeneEPHB6chr14:75265473chr7:142568562ENST0000039295702032_59401022.0Topological domainExtracellular
TgeneEPHB6chr14:75265473chr7:142568562ENST00000392957020616_102101022.0Topological domainCytoplasmic
TgeneEPHB6chr14:75265473chr7:142568562ENST0000044212902032_59401022.0Topological domainExtracellular
TgeneEPHB6chr14:75265473chr7:142568562ENST00000442129020616_102101022.0Topological domainCytoplasmic
TgeneEPHB6chr14:75265473chr7:142568562ENST00000392957020595_61501022.0TransmembraneHelical
TgeneEPHB6chr14:75265473chr7:142568562ENST00000442129020595_61501022.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneYLPM1chr14:75265473chr7:142568562ENST00000238571+1161002_140401823.0Compositional biasNote=Arg-rich
HgeneYLPM1chr14:75265473chr7:142568562ENST00000238571+11615_20501823.0Compositional biasNote=Pro-rich
HgeneYLPM1chr14:75265473chr7:142568562ENST00000238571+1161683_177201823.0Compositional biasNote=Arg-rich
HgeneYLPM1chr14:75265473chr7:142568562ENST00000238571+116382_43001823.0Compositional biasNote=Gln-rich
HgeneYLPM1chr14:75265473chr7:142568562ENST00000325680+1211002_140401953.3333333333333Compositional biasNote=Arg-rich
HgeneYLPM1chr14:75265473chr7:142568562ENST00000325680+12115_20501953.3333333333333Compositional biasNote=Pro-rich
HgeneYLPM1chr14:75265473chr7:142568562ENST00000325680+1211683_177201953.3333333333333Compositional biasNote=Arg-rich
HgeneYLPM1chr14:75265473chr7:142568562ENST00000325680+121382_43001953.3333333333333Compositional biasNote=Gln-rich


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Fusion Gene Sequence for YLPM1-EPHB6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>100034_100034_1_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000238571_EPHB6_chr7_142568562_ENST00000392957_length(transcript)=3033nt_BP=2748nt
GTTTACACGCTCCGGGGCCTGTAGGCGCCGCGAGTTCCGGCTGTCGCCGTCGCCGCCGCGGCTCCTGGAGGTCGGTTGCGACGAGTAACG
GCGCCAGGACGAGCCCTGCGCCTTCTTTTTCGATATGTACCCGAATTGGGGCCGGTATGGCGGGAGCAGCCACTATCCGCCGCCACCGGT
CCCACCGCCGCCGCCAGTGGCGCTTCCTGAGGCCTCGCCGGGGCCCGGGTACTCGAGCTCGACGACTCCCGCGGCCCCCTCCTCCTCGGG
CTTCATGAGCTTCCGCGAACAGCACTTGGCGCAGCTCCAGCAGCTGCAGCAGATGCACCAGAAGCAAATGCAGTGCGTGCTTCAGCCCCA
CCACCTTCCTCCGCCCCCTCTGCCGCCCCCGCCAGTGATGCCGGGGGGCGGCTACGGAGACTGGCAGCCGCCACCGCCACCGATGCCCCC
GCCACCCGGGCCGGCCCTCAGCTATCAGAAGCAGCAGCAGTACAAACACCAGATGCTCCACCACCAACGAGACGGGCCTCCTGGTTTGGT
TCCAATGGAGCTGGAATCCCCCCCTGAATCTCCCCCTGTGCCGCCTGGGTCCTATATGCCCCCATCTCAGTCTTACATGCCCCCACCTCA
GCCGCCACCCTCTTACTACCCCCCGACCTCATCTCAGCCCTACCTGCCTCCTGCTCAGCCGTCCCCTTCGCAGTCCCCACCTTCCCAATC
CTACCTGGCGCCCACCCCTTCTTACTCATCCTCCTCCTCTTCCTCGCAATCCTATTTGAGCCATTCCCAGTCCTACTTGCCCTCTTCTCA
GGCATCTCCTTCCCGCCCCTCCCAGGGCCATTCTAAATCCCAACTACTAGCTCCACCACCACCGTCCGCCCCCCCTGGAAATAAGACAAC
TGTCCAGCAAGAGCCTTTGGAGAGTGGGGCCAAAAACAAGAGTACTGAACAGCAGCAAGCCGCCCCTGAGCCAGATCCCTCTACGATGAC
TCCACAGGAACAGCAGCAGTATTGGTATCGACAGCACTTGCTTAGTTTGCAACAGAGGACAAAAGTTCATTTGCCAGGACACAAAAAGGG
TCCTGTGGTAGCAAAGGATACACCAGAGCCGGTAAAAGAAGAAGTTACAGTACCTGCCACCAGTCAAGTTCCAGAATCTCCTTCTTCTGA
GGAGCCCCCATTGCCACCTCCAAATGAGGAAGTGCCACCTCCTCTCCCACCTGAGGAACCCCAGTCTGAGGACCCAGAAGAAGATGCCAG
GTTAAAGCAGTTGCAGGCTGCAGCAGCACACTGGCAGCAGCACCAGCAGCATCGAGTCGGTTTCCAGTATCAGGGAATAATGCAGAAGCA
CACTCAGTTACAGCAGATTCTACAACAGTATCAGCAGATTATACAGCCCCCACCACATATACAGGCAACTACACCTCCTCCAGGAATACC
TCCCCCTGGAGTTCCACAAGGGATACCTCCTCAGTTAACAGCAGCCCCAGTTCCACCAGCCTCCAGTTCACAGAGCTCGCAAGTTCCAGA
GAAACCTAGACCAGCACTGCTTCCTACTCCTGTGTCTTTTGGTTCTGCCCCACCGACAACTTACCATCCTCCGTTGCAATCAGCTGGTCC
ATCAGAACAAGTGAATTCAAAAGCTCCTTTGAGCAAGTCTGCTCTGCCATACAGTTCATTCTCATCTGATCAAGGACTTGGGGAGTCTTC
AGCTGCTCCATCTCAGCCAATCACTGCAGTGAAGGACATGCCAGTGAGATCAGGTGGCCTGCTTCCAGATCCTCCTAGAAGTAGTTACTT
GGAAAGTCCAAGAGGCCCAAGAAGATCAGATTTTGGTCGTGATAGAGGTCCATTCAGACCAGAACCAGGAGATGGTGGGGAAAAAATGTA
TCCATATCACCGGGATGAGCCTCCTAGGGCTCCATGGAACCATGGAGAAGAGCGAGGGCATGAAGAGTTTCCATTAGATGGTAGAAATGC
TCCAATGGAACGAGAAAGACTCGATGACTGGGATAGAGAGAGATACTGGAGAGAATGTGAACGTGACTATCAAGATGATACACTAGAGCT
CTATAACAGAGAGGACAGGTTCTCAGCACCACCATCTCGGTCTCATGATGGAGATAGGCGAGGCCCTTGGTGGGATGATTGGGAGAGAGA
CCAGGATATGGATGAGGACTACAATAGGGAAATGGAAAGGGACATGGACAGGGATGTGGATCGGATTTCAAGACCTATGGATATGTATGA
TAGAAGTTTGGATAATGAGTGGGACAGAGATTATGGGAGACCACTGGATGAACAAGAATCACAGTTTCGTGAACGGGATATTCCATCTCT
TCCACCTTTACCGCCCCTCCCACCTCTTCCACCTTTGGATAGATATCGGGATGATAGATGGAGAGAAGAAAGAAATCGAGAGCATGGGTA
TGATCGAGATTTCCGTGATAGGGGTGAGTTGAGGATTCGAGAGTATCCAGAAAGAGGAGATACATGGCGGGAAAAGCGAGATTATGTTCC
TGACAGAATGGACTGGGAAAGAGAACGGTTGTCAGACAGATGGTACCCATCTGATGTGGATAGACATTCCCCCATGGCGGAACATATGCC
CTCCTCACATCATTCCTCAGAAATGATGGGGTCCGATGCAAGCTTAGACTCTGACCAAGGCCTTGGAGGGGTAATGGTTCTCAGTCAGAG
GCAGCATGAAATCATTTTGAAAGCTGCACAAGAACTGAAAATGCTTCGTGGGCATCACCCTGGCTGGCCACCAGAAGAAGCTGCTGCACC
ACATCCAGCTCCTTCAGCAACACCTGAGGCAGCAGGGCTCAGTGGAGGTCTGAGAATGACGATACCCGTGACTCAGCCCTGGACACTGGT
CCGAGAAGGGACATGTGGGACGTGAGCCGGGCTCCAACAGCCTCTGTGAGAGATGCCCCACACCAAACCCAACCCTCCCGATGGCTGCAT

>100034_100034_1_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000238571_EPHB6_chr7_142568562_ENST00000392957_length(amino acids)=926AA_BP=875
MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPP
VMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS
QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAK
NKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEV
PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQATTPPPGIPPPGVPQGIPPQ
LTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVK
DMPVRSGGLLPDPPRSSYLESPRGPRRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWD
RERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDY
GRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKRDYVPDRMDWERERLS
DRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLRGHHPGWPPEEAAAPHPAPSATPEAA

--------------------------------------------------------------
>100034_100034_2_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000238571_EPHB6_chr7_142568562_ENST00000411471_length(transcript)=3033nt_BP=2748nt
GTTTACACGCTCCGGGGCCTGTAGGCGCCGCGAGTTCCGGCTGTCGCCGTCGCCGCCGCGGCTCCTGGAGGTCGGTTGCGACGAGTAACG
GCGCCAGGACGAGCCCTGCGCCTTCTTTTTCGATATGTACCCGAATTGGGGCCGGTATGGCGGGAGCAGCCACTATCCGCCGCCACCGGT
CCCACCGCCGCCGCCAGTGGCGCTTCCTGAGGCCTCGCCGGGGCCCGGGTACTCGAGCTCGACGACTCCCGCGGCCCCCTCCTCCTCGGG
CTTCATGAGCTTCCGCGAACAGCACTTGGCGCAGCTCCAGCAGCTGCAGCAGATGCACCAGAAGCAAATGCAGTGCGTGCTTCAGCCCCA
CCACCTTCCTCCGCCCCCTCTGCCGCCCCCGCCAGTGATGCCGGGGGGCGGCTACGGAGACTGGCAGCCGCCACCGCCACCGATGCCCCC
GCCACCCGGGCCGGCCCTCAGCTATCAGAAGCAGCAGCAGTACAAACACCAGATGCTCCACCACCAACGAGACGGGCCTCCTGGTTTGGT
TCCAATGGAGCTGGAATCCCCCCCTGAATCTCCCCCTGTGCCGCCTGGGTCCTATATGCCCCCATCTCAGTCTTACATGCCCCCACCTCA
GCCGCCACCCTCTTACTACCCCCCGACCTCATCTCAGCCCTACCTGCCTCCTGCTCAGCCGTCCCCTTCGCAGTCCCCACCTTCCCAATC
CTACCTGGCGCCCACCCCTTCTTACTCATCCTCCTCCTCTTCCTCGCAATCCTATTTGAGCCATTCCCAGTCCTACTTGCCCTCTTCTCA
GGCATCTCCTTCCCGCCCCTCCCAGGGCCATTCTAAATCCCAACTACTAGCTCCACCACCACCGTCCGCCCCCCCTGGAAATAAGACAAC
TGTCCAGCAAGAGCCTTTGGAGAGTGGGGCCAAAAACAAGAGTACTGAACAGCAGCAAGCCGCCCCTGAGCCAGATCCCTCTACGATGAC
TCCACAGGAACAGCAGCAGTATTGGTATCGACAGCACTTGCTTAGTTTGCAACAGAGGACAAAAGTTCATTTGCCAGGACACAAAAAGGG
TCCTGTGGTAGCAAAGGATACACCAGAGCCGGTAAAAGAAGAAGTTACAGTACCTGCCACCAGTCAAGTTCCAGAATCTCCTTCTTCTGA
GGAGCCCCCATTGCCACCTCCAAATGAGGAAGTGCCACCTCCTCTCCCACCTGAGGAACCCCAGTCTGAGGACCCAGAAGAAGATGCCAG
GTTAAAGCAGTTGCAGGCTGCAGCAGCACACTGGCAGCAGCACCAGCAGCATCGAGTCGGTTTCCAGTATCAGGGAATAATGCAGAAGCA
CACTCAGTTACAGCAGATTCTACAACAGTATCAGCAGATTATACAGCCCCCACCACATATACAGGCAACTACACCTCCTCCAGGAATACC
TCCCCCTGGAGTTCCACAAGGGATACCTCCTCAGTTAACAGCAGCCCCAGTTCCACCAGCCTCCAGTTCACAGAGCTCGCAAGTTCCAGA
GAAACCTAGACCAGCACTGCTTCCTACTCCTGTGTCTTTTGGTTCTGCCCCACCGACAACTTACCATCCTCCGTTGCAATCAGCTGGTCC
ATCAGAACAAGTGAATTCAAAAGCTCCTTTGAGCAAGTCTGCTCTGCCATACAGTTCATTCTCATCTGATCAAGGACTTGGGGAGTCTTC
AGCTGCTCCATCTCAGCCAATCACTGCAGTGAAGGACATGCCAGTGAGATCAGGTGGCCTGCTTCCAGATCCTCCTAGAAGTAGTTACTT
GGAAAGTCCAAGAGGCCCAAGAAGATCAGATTTTGGTCGTGATAGAGGTCCATTCAGACCAGAACCAGGAGATGGTGGGGAAAAAATGTA
TCCATATCACCGGGATGAGCCTCCTAGGGCTCCATGGAACCATGGAGAAGAGCGAGGGCATGAAGAGTTTCCATTAGATGGTAGAAATGC
TCCAATGGAACGAGAAAGACTCGATGACTGGGATAGAGAGAGATACTGGAGAGAATGTGAACGTGACTATCAAGATGATACACTAGAGCT
CTATAACAGAGAGGACAGGTTCTCAGCACCACCATCTCGGTCTCATGATGGAGATAGGCGAGGCCCTTGGTGGGATGATTGGGAGAGAGA
CCAGGATATGGATGAGGACTACAATAGGGAAATGGAAAGGGACATGGACAGGGATGTGGATCGGATTTCAAGACCTATGGATATGTATGA
TAGAAGTTTGGATAATGAGTGGGACAGAGATTATGGGAGACCACTGGATGAACAAGAATCACAGTTTCGTGAACGGGATATTCCATCTCT
TCCACCTTTACCGCCCCTCCCACCTCTTCCACCTTTGGATAGATATCGGGATGATAGATGGAGAGAAGAAAGAAATCGAGAGCATGGGTA
TGATCGAGATTTCCGTGATAGGGGTGAGTTGAGGATTCGAGAGTATCCAGAAAGAGGAGATACATGGCGGGAAAAGCGAGATTATGTTCC
TGACAGAATGGACTGGGAAAGAGAACGGTTGTCAGACAGATGGTACCCATCTGATGTGGATAGACATTCCCCCATGGCGGAACATATGCC
CTCCTCACATCATTCCTCAGAAATGATGGGGTCCGATGCAAGCTTAGACTCTGACCAAGGCCTTGGAGGGGTAATGGTTCTCAGTCAGAG
GCAGCATGAAATCATTTTGAAAGCTGCACAAGAACTGAAAATGCTTCGTGGGCATCACCCTGGCTGGCCACCAGAAGAAGCTGCTGCACC
ACATCCAGCTCCTTCAGCAACACCTGAGGCAGCAGGGCTCAGTGGAGGTCTGAGAATGACGATACCCGTGACTCAGCCCTGGACACTGGT
CCGAGAAGGGACATGTGGGACGTGAGCCGGGCTCCAACAGCCTCTGTGAGAGATGCCCCACACCAAACCCAACCCTCCCGATGGCTGCAT

>100034_100034_2_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000238571_EPHB6_chr7_142568562_ENST00000411471_length(amino acids)=926AA_BP=875
MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPP
VMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS
QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAK
NKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEV
PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQATTPPPGIPPPGVPQGIPPQ
LTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVK
DMPVRSGGLLPDPPRSSYLESPRGPRRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWD
RERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDY
GRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKRDYVPDRMDWERERLS
DRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLRGHHPGWPPEEAAAPHPAPSATPEAA

--------------------------------------------------------------
>100034_100034_3_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000238571_EPHB6_chr7_142568562_ENST00000442129_length(transcript)=3033nt_BP=2748nt
GTTTACACGCTCCGGGGCCTGTAGGCGCCGCGAGTTCCGGCTGTCGCCGTCGCCGCCGCGGCTCCTGGAGGTCGGTTGCGACGAGTAACG
GCGCCAGGACGAGCCCTGCGCCTTCTTTTTCGATATGTACCCGAATTGGGGCCGGTATGGCGGGAGCAGCCACTATCCGCCGCCACCGGT
CCCACCGCCGCCGCCAGTGGCGCTTCCTGAGGCCTCGCCGGGGCCCGGGTACTCGAGCTCGACGACTCCCGCGGCCCCCTCCTCCTCGGG
CTTCATGAGCTTCCGCGAACAGCACTTGGCGCAGCTCCAGCAGCTGCAGCAGATGCACCAGAAGCAAATGCAGTGCGTGCTTCAGCCCCA
CCACCTTCCTCCGCCCCCTCTGCCGCCCCCGCCAGTGATGCCGGGGGGCGGCTACGGAGACTGGCAGCCGCCACCGCCACCGATGCCCCC
GCCACCCGGGCCGGCCCTCAGCTATCAGAAGCAGCAGCAGTACAAACACCAGATGCTCCACCACCAACGAGACGGGCCTCCTGGTTTGGT
TCCAATGGAGCTGGAATCCCCCCCTGAATCTCCCCCTGTGCCGCCTGGGTCCTATATGCCCCCATCTCAGTCTTACATGCCCCCACCTCA
GCCGCCACCCTCTTACTACCCCCCGACCTCATCTCAGCCCTACCTGCCTCCTGCTCAGCCGTCCCCTTCGCAGTCCCCACCTTCCCAATC
CTACCTGGCGCCCACCCCTTCTTACTCATCCTCCTCCTCTTCCTCGCAATCCTATTTGAGCCATTCCCAGTCCTACTTGCCCTCTTCTCA
GGCATCTCCTTCCCGCCCCTCCCAGGGCCATTCTAAATCCCAACTACTAGCTCCACCACCACCGTCCGCCCCCCCTGGAAATAAGACAAC
TGTCCAGCAAGAGCCTTTGGAGAGTGGGGCCAAAAACAAGAGTACTGAACAGCAGCAAGCCGCCCCTGAGCCAGATCCCTCTACGATGAC
TCCACAGGAACAGCAGCAGTATTGGTATCGACAGCACTTGCTTAGTTTGCAACAGAGGACAAAAGTTCATTTGCCAGGACACAAAAAGGG
TCCTGTGGTAGCAAAGGATACACCAGAGCCGGTAAAAGAAGAAGTTACAGTACCTGCCACCAGTCAAGTTCCAGAATCTCCTTCTTCTGA
GGAGCCCCCATTGCCACCTCCAAATGAGGAAGTGCCACCTCCTCTCCCACCTGAGGAACCCCAGTCTGAGGACCCAGAAGAAGATGCCAG
GTTAAAGCAGTTGCAGGCTGCAGCAGCACACTGGCAGCAGCACCAGCAGCATCGAGTCGGTTTCCAGTATCAGGGAATAATGCAGAAGCA
CACTCAGTTACAGCAGATTCTACAACAGTATCAGCAGATTATACAGCCCCCACCACATATACAGGCAACTACACCTCCTCCAGGAATACC
TCCCCCTGGAGTTCCACAAGGGATACCTCCTCAGTTAACAGCAGCCCCAGTTCCACCAGCCTCCAGTTCACAGAGCTCGCAAGTTCCAGA
GAAACCTAGACCAGCACTGCTTCCTACTCCTGTGTCTTTTGGTTCTGCCCCACCGACAACTTACCATCCTCCGTTGCAATCAGCTGGTCC
ATCAGAACAAGTGAATTCAAAAGCTCCTTTGAGCAAGTCTGCTCTGCCATACAGTTCATTCTCATCTGATCAAGGACTTGGGGAGTCTTC
AGCTGCTCCATCTCAGCCAATCACTGCAGTGAAGGACATGCCAGTGAGATCAGGTGGCCTGCTTCCAGATCCTCCTAGAAGTAGTTACTT
GGAAAGTCCAAGAGGCCCAAGAAGATCAGATTTTGGTCGTGATAGAGGTCCATTCAGACCAGAACCAGGAGATGGTGGGGAAAAAATGTA
TCCATATCACCGGGATGAGCCTCCTAGGGCTCCATGGAACCATGGAGAAGAGCGAGGGCATGAAGAGTTTCCATTAGATGGTAGAAATGC
TCCAATGGAACGAGAAAGACTCGATGACTGGGATAGAGAGAGATACTGGAGAGAATGTGAACGTGACTATCAAGATGATACACTAGAGCT
CTATAACAGAGAGGACAGGTTCTCAGCACCACCATCTCGGTCTCATGATGGAGATAGGCGAGGCCCTTGGTGGGATGATTGGGAGAGAGA
CCAGGATATGGATGAGGACTACAATAGGGAAATGGAAAGGGACATGGACAGGGATGTGGATCGGATTTCAAGACCTATGGATATGTATGA
TAGAAGTTTGGATAATGAGTGGGACAGAGATTATGGGAGACCACTGGATGAACAAGAATCACAGTTTCGTGAACGGGATATTCCATCTCT
TCCACCTTTACCGCCCCTCCCACCTCTTCCACCTTTGGATAGATATCGGGATGATAGATGGAGAGAAGAAAGAAATCGAGAGCATGGGTA
TGATCGAGATTTCCGTGATAGGGGTGAGTTGAGGATTCGAGAGTATCCAGAAAGAGGAGATACATGGCGGGAAAAGCGAGATTATGTTCC
TGACAGAATGGACTGGGAAAGAGAACGGTTGTCAGACAGATGGTACCCATCTGATGTGGATAGACATTCCCCCATGGCGGAACATATGCC
CTCCTCACATCATTCCTCAGAAATGATGGGGTCCGATGCAAGCTTAGACTCTGACCAAGGCCTTGGAGGGGTAATGGTTCTCAGTCAGAG
GCAGCATGAAATCATTTTGAAAGCTGCACAAGAACTGAAAATGCTTCGTGGGCATCACCCTGGCTGGCCACCAGAAGAAGCTGCTGCACC
ACATCCAGCTCCTTCAGCAACACCTGAGGCAGCAGGGCTCAGTGGAGGTCTGAGAATGACGATACCCGTGACTCAGCCCTGGACACTGGT
CCGAGAAGGGACATGTGGGACGTGAGCCGGGCTCCAACAGCCTCTGTGAGAGATGCCCCACACCAAACCCAACCCTCCCGATGGCTGCAT

>100034_100034_3_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000238571_EPHB6_chr7_142568562_ENST00000442129_length(amino acids)=926AA_BP=875
MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPP
VMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS
QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAK
NKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEV
PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQATTPPPGIPPPGVPQGIPPQ
LTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVK
DMPVRSGGLLPDPPRSSYLESPRGPRRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWD
RERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDY
GRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKRDYVPDRMDWERERLS
DRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLRGHHPGWPPEEAAAPHPAPSATPEAA

--------------------------------------------------------------
>100034_100034_4_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000325680_EPHB6_chr7_142568562_ENST00000392957_length(transcript)=3618nt_BP=3333nt
GTTTACACGCTCCGGGGCCTGTAGGCGCCGCGAGTTCCGGCTGTCGCCGTCGCCGCCGCGGCTCCTGGAGGTCGGTTGCGACGAGTAACG
GCGCCAGGACGAGCCCTGCGCCTTCTTTTTCGATATGTACCCGAATTGGGGCCGGTATGGCGGGAGCAGCCACTATCCGCCGCCACCGGT
CCCACCGCCGCCGCCAGTGGCGCTTCCTGAGGCCTCGCCGGGGCCCGGGTACTCGAGCTCGACGACTCCCGCGGCCCCCTCCTCCTCGGG
CTTCATGAGCTTCCGCGAACAGCACTTGGCGCAGCTCCAGCAGCTGCAGCAGATGCACCAGAAGCAAATGCAGTGCGTGCTTCAGCCCCA
CCACCTTCCTCCGCCCCCTCTGCCGCCCCCGCCAGTGATGCCGGGGGGCGGCTACGGAGACTGGCAGCCGCCACCGCCACCGATGCCCCC
GCCACCCGGGCCGGCCCTCAGCTATCAGAAGCAGCAGCAGTACAAACACCAGATGCTCCACCACCAACGAGACGGGCCTCCTGGTTTGGT
TCCAATGGAGCTGGAATCCCCCCCTGAATCTCCCCCTGTGCCGCCTGGGTCCTATATGCCCCCATCTCAGTCTTACATGCCCCCACCTCA
GCCGCCACCCTCTTACTACCCCCCGACCTCATCTCAGCCCTACCTGCCTCCTGCTCAGCCGTCCCCTTCGCAGTCCCCACCTTCCCAATC
CTACCTGGCGCCCACCCCTTCTTACTCATCCTCCTCCTCTTCCTCGCAATCCTATTTGAGCCATTCCCAGTCCTACTTGCCCTCTTCTCA
GGCATCTCCTTCCCGCCCCTCCCAGGGCCATTCTAAATCCCAACTACTAGCTCCACCACCACCGTCCGCCCCCCCTGGAAATAAGACAAC
TGTCCAGCAAGAGCCTTTGGAGAGTGGGGCCAAAAACAAGAGTACTGAACAGCAGCAAGCCGCCCCTGAGCCAGATCCCTCTACGATGAC
TCCACAGGAACAGCAGCAGTATTGGTATCGACAGCACTTGCTTAGTTTGCAACAGAGGACAAAAGTTCATTTGCCAGGACACAAAAAGGG
TCCTGTGGTAGCAAAGGATACACCAGAGCCGGTAAAAGAAGAAGTTACAGTACCTGCCACCAGTCAAGTTCCAGAATCTCCTTCTTCTGA
GGAGCCCCCATTGCCACCTCCAAATGAGGAAGTGCCACCTCCTCTCCCACCTGAGGAACCCCAGTCTGAGGACCCAGAAGAAGATGCCAG
GTTAAAGCAGTTGCAGGCTGCAGCAGCACACTGGCAGCAGCACCAGCAGCATCGAGTCGGTTTCCAGTATCAGGGAATAATGCAGAAGCA
CACTCAGTTACAGCAGATTCTACAACAGTATCAGCAGATTATACAGCCCCCACCACATATACAGACCATGTCTGTAGATATGCAGCTGCG
GCATTATGAGATGCAGCAGCAACAGTTTCAACATCTTTACCAAGAATGGGAGCGAGAGTTTCAGCTATGGGAGGAACAACTCCATTCCTA
TCCTCATAAAGATCAGCTTCAGGAGTATGAGAAGCAGTGGAAAACATGGCAGGGACATATGAAAGCCACTCAGAGCTATCTCCAGGAGAA
AGTCAATTCATTTCAGAACATGAAGAACCAGTATATGGGGAACATGTCAATGCCACCTCCTTTTGTTCCATATTCTCAGATGCCTCCACC
TCTACCTACAATGCCCCCTCCAGTGTTGCCTCCTTCATTGCCACCACCAGTGATGCCCCCTGCCCTCCCTGCTACAGTGCCACCACCTGG
CATGCCCCCACCTGTTATGCCACCTTCTCTACCAACCTCTGTTCCCCCACCAGGGATGCCTCCTTCTCTCTCTTCTGCAGGGCCACCACC
AGTTCTCCCCCCACCTTCCCTGTCTTCTGCAGGGCCACCACCAGTTCTTCCCCCACCATCTCTCTCTTCAACAGCACCTCCACCTGTCAT
GCCCCTCCCACCATTGTCTTCAGCTACACCTCCTCCAGGAATACCTCCCCCTGGAGTTCCACAAGGGATACCTCCTCAGTTAACAGCAGC
CCCAGTTCCACCAGCCTCCAGTTCACAGAGCTCGCAAGTTCCAGAGAAACCTAGACCAGCACTGCTTCCTACTCCTGTGTCTTTTGGTTC
TGCCCCACCGACAACTTACCATCCTCCGTTGCAATCAGCTGGTCCATCAGAACAAGTGAATTCAAAAGCTCCTTTGAGCAAGTCTGCTCT
GCCATACAGTTCATTCTCATCTGATCAAGGACTTGGGGAGTCTTCAGCTGCTCCATCTCAGCCAATCACTGCAGTGAAGGACATGCCAGT
GAGATCAGGTGGCCTGCTTCCAGATCCTCCTAGAAGTAGTTACTTGGAAAGTCCAAGAGGCCCAAGAAGATCAGATTTTGGTCGTGATAG
AGGTCCATTCAGACCAGAACCAGGAGATGGTGGGGAAAAAATGTATCCATATCACCGGGATGAGCCTCCTAGGGCTCCATGGAACCATGG
AGAAGAGCGAGGGCATGAAGAGTTTCCATTAGATGGTAGAAATGCTCCAATGGAACGAGAAAGACTCGATGACTGGGATAGAGAGAGATA
CTGGAGAGAATGTGAACGTGACTATCAAGATGATACACTAGAGCTCTATAACAGAGAGGACAGGTTCTCAGCACCACCATCTCGGTCTCA
TGATGGAGATAGGCGAGGCCCTTGGTGGGATGATTGGGAGAGAGACCAGGATATGGATGAGGACTACAATAGGGAAATGGAAAGGGACAT
GGACAGGGATGTGGATCGGATTTCAAGACCTATGGATATGTATGATAGAAGTTTGGATAATGAGTGGGACAGAGATTATGGGAGACCACT
GGATGAACAAGAATCACAGTTTCGTGAACGGGATATTCCATCTCTTCCACCTTTACCGCCCCTCCCACCTCTTCCACCTTTGGATAGATA
TCGGGATGATAGATGGAGAGAAGAAAGAAATCGAGAGCATGGGTATGATCGAGATTTCCGTGATAGGGGTGAGTTGAGGATTCGAGAGTA
TCCAGAAAGAGGAGATACATGGCGGGAAAAGCGAGATTATGTTCCTGACAGAATGGACTGGGAAAGAGAACGGTTGTCAGACAGATGGTA
CCCATCTGATGTGGATAGACATTCCCCCATGGCGGAACATATGCCCTCCTCACATCATTCCTCAGAAATGATGGGGTCCGATGCAAGCTT
AGACTCTGACCAAGGCCTTGGAGGGGTAATGGTTCTCAGTCAGAGGCAGCATGAAATCATTTTGAAAGCTGCACAAGAACTGAAAATGCT
TCGTGGGCATCACCCTGGCTGGCCACCAGAAGAAGCTGCTGCACCACATCCAGCTCCTTCAGCAACACCTGAGGCAGCAGGGCTCAGTGG
AGGTCTGAGAATGACGATACCCGTGACTCAGCCCTGGACACTGGTCCGAGAAGGGACATGTGGGACGTGAGCCGGGCTCCAACAGCCTCT
GTGAGAGATGCCCCACACCAAACCCAACCCTCCCGATGGCTGCATTCCCTGGTCCTCCGCCTCTCCACCAGCCCCCTCCTCATTAAAGGG

>100034_100034_4_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000325680_EPHB6_chr7_142568562_ENST00000392957_length(amino acids)=1121AA_BP=1070
MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPP
VMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS
QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAK
NKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEV
PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQH
LYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPP
SLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPP
PGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL
GESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEFPLD
GRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPM
DMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKR
DYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLRGHHPGWPPEE

--------------------------------------------------------------
>100034_100034_5_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000325680_EPHB6_chr7_142568562_ENST00000411471_length(transcript)=3618nt_BP=3333nt
GTTTACACGCTCCGGGGCCTGTAGGCGCCGCGAGTTCCGGCTGTCGCCGTCGCCGCCGCGGCTCCTGGAGGTCGGTTGCGACGAGTAACG
GCGCCAGGACGAGCCCTGCGCCTTCTTTTTCGATATGTACCCGAATTGGGGCCGGTATGGCGGGAGCAGCCACTATCCGCCGCCACCGGT
CCCACCGCCGCCGCCAGTGGCGCTTCCTGAGGCCTCGCCGGGGCCCGGGTACTCGAGCTCGACGACTCCCGCGGCCCCCTCCTCCTCGGG
CTTCATGAGCTTCCGCGAACAGCACTTGGCGCAGCTCCAGCAGCTGCAGCAGATGCACCAGAAGCAAATGCAGTGCGTGCTTCAGCCCCA
CCACCTTCCTCCGCCCCCTCTGCCGCCCCCGCCAGTGATGCCGGGGGGCGGCTACGGAGACTGGCAGCCGCCACCGCCACCGATGCCCCC
GCCACCCGGGCCGGCCCTCAGCTATCAGAAGCAGCAGCAGTACAAACACCAGATGCTCCACCACCAACGAGACGGGCCTCCTGGTTTGGT
TCCAATGGAGCTGGAATCCCCCCCTGAATCTCCCCCTGTGCCGCCTGGGTCCTATATGCCCCCATCTCAGTCTTACATGCCCCCACCTCA
GCCGCCACCCTCTTACTACCCCCCGACCTCATCTCAGCCCTACCTGCCTCCTGCTCAGCCGTCCCCTTCGCAGTCCCCACCTTCCCAATC
CTACCTGGCGCCCACCCCTTCTTACTCATCCTCCTCCTCTTCCTCGCAATCCTATTTGAGCCATTCCCAGTCCTACTTGCCCTCTTCTCA
GGCATCTCCTTCCCGCCCCTCCCAGGGCCATTCTAAATCCCAACTACTAGCTCCACCACCACCGTCCGCCCCCCCTGGAAATAAGACAAC
TGTCCAGCAAGAGCCTTTGGAGAGTGGGGCCAAAAACAAGAGTACTGAACAGCAGCAAGCCGCCCCTGAGCCAGATCCCTCTACGATGAC
TCCACAGGAACAGCAGCAGTATTGGTATCGACAGCACTTGCTTAGTTTGCAACAGAGGACAAAAGTTCATTTGCCAGGACACAAAAAGGG
TCCTGTGGTAGCAAAGGATACACCAGAGCCGGTAAAAGAAGAAGTTACAGTACCTGCCACCAGTCAAGTTCCAGAATCTCCTTCTTCTGA
GGAGCCCCCATTGCCACCTCCAAATGAGGAAGTGCCACCTCCTCTCCCACCTGAGGAACCCCAGTCTGAGGACCCAGAAGAAGATGCCAG
GTTAAAGCAGTTGCAGGCTGCAGCAGCACACTGGCAGCAGCACCAGCAGCATCGAGTCGGTTTCCAGTATCAGGGAATAATGCAGAAGCA
CACTCAGTTACAGCAGATTCTACAACAGTATCAGCAGATTATACAGCCCCCACCACATATACAGACCATGTCTGTAGATATGCAGCTGCG
GCATTATGAGATGCAGCAGCAACAGTTTCAACATCTTTACCAAGAATGGGAGCGAGAGTTTCAGCTATGGGAGGAACAACTCCATTCCTA
TCCTCATAAAGATCAGCTTCAGGAGTATGAGAAGCAGTGGAAAACATGGCAGGGACATATGAAAGCCACTCAGAGCTATCTCCAGGAGAA
AGTCAATTCATTTCAGAACATGAAGAACCAGTATATGGGGAACATGTCAATGCCACCTCCTTTTGTTCCATATTCTCAGATGCCTCCACC
TCTACCTACAATGCCCCCTCCAGTGTTGCCTCCTTCATTGCCACCACCAGTGATGCCCCCTGCCCTCCCTGCTACAGTGCCACCACCTGG
CATGCCCCCACCTGTTATGCCACCTTCTCTACCAACCTCTGTTCCCCCACCAGGGATGCCTCCTTCTCTCTCTTCTGCAGGGCCACCACC
AGTTCTCCCCCCACCTTCCCTGTCTTCTGCAGGGCCACCACCAGTTCTTCCCCCACCATCTCTCTCTTCAACAGCACCTCCACCTGTCAT
GCCCCTCCCACCATTGTCTTCAGCTACACCTCCTCCAGGAATACCTCCCCCTGGAGTTCCACAAGGGATACCTCCTCAGTTAACAGCAGC
CCCAGTTCCACCAGCCTCCAGTTCACAGAGCTCGCAAGTTCCAGAGAAACCTAGACCAGCACTGCTTCCTACTCCTGTGTCTTTTGGTTC
TGCCCCACCGACAACTTACCATCCTCCGTTGCAATCAGCTGGTCCATCAGAACAAGTGAATTCAAAAGCTCCTTTGAGCAAGTCTGCTCT
GCCATACAGTTCATTCTCATCTGATCAAGGACTTGGGGAGTCTTCAGCTGCTCCATCTCAGCCAATCACTGCAGTGAAGGACATGCCAGT
GAGATCAGGTGGCCTGCTTCCAGATCCTCCTAGAAGTAGTTACTTGGAAAGTCCAAGAGGCCCAAGAAGATCAGATTTTGGTCGTGATAG
AGGTCCATTCAGACCAGAACCAGGAGATGGTGGGGAAAAAATGTATCCATATCACCGGGATGAGCCTCCTAGGGCTCCATGGAACCATGG
AGAAGAGCGAGGGCATGAAGAGTTTCCATTAGATGGTAGAAATGCTCCAATGGAACGAGAAAGACTCGATGACTGGGATAGAGAGAGATA
CTGGAGAGAATGTGAACGTGACTATCAAGATGATACACTAGAGCTCTATAACAGAGAGGACAGGTTCTCAGCACCACCATCTCGGTCTCA
TGATGGAGATAGGCGAGGCCCTTGGTGGGATGATTGGGAGAGAGACCAGGATATGGATGAGGACTACAATAGGGAAATGGAAAGGGACAT
GGACAGGGATGTGGATCGGATTTCAAGACCTATGGATATGTATGATAGAAGTTTGGATAATGAGTGGGACAGAGATTATGGGAGACCACT
GGATGAACAAGAATCACAGTTTCGTGAACGGGATATTCCATCTCTTCCACCTTTACCGCCCCTCCCACCTCTTCCACCTTTGGATAGATA
TCGGGATGATAGATGGAGAGAAGAAAGAAATCGAGAGCATGGGTATGATCGAGATTTCCGTGATAGGGGTGAGTTGAGGATTCGAGAGTA
TCCAGAAAGAGGAGATACATGGCGGGAAAAGCGAGATTATGTTCCTGACAGAATGGACTGGGAAAGAGAACGGTTGTCAGACAGATGGTA
CCCATCTGATGTGGATAGACATTCCCCCATGGCGGAACATATGCCCTCCTCACATCATTCCTCAGAAATGATGGGGTCCGATGCAAGCTT
AGACTCTGACCAAGGCCTTGGAGGGGTAATGGTTCTCAGTCAGAGGCAGCATGAAATCATTTTGAAAGCTGCACAAGAACTGAAAATGCT
TCGTGGGCATCACCCTGGCTGGCCACCAGAAGAAGCTGCTGCACCACATCCAGCTCCTTCAGCAACACCTGAGGCAGCAGGGCTCAGTGG
AGGTCTGAGAATGACGATACCCGTGACTCAGCCCTGGACACTGGTCCGAGAAGGGACATGTGGGACGTGAGCCGGGCTCCAACAGCCTCT
GTGAGAGATGCCCCACACCAAACCCAACCCTCCCGATGGCTGCATTCCCTGGTCCTCCGCCTCTCCACCAGCCCCCTCCTCATTAAAGGG

>100034_100034_5_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000325680_EPHB6_chr7_142568562_ENST00000411471_length(amino acids)=1121AA_BP=1070
MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPP
VMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS
QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAK
NKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEV
PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQH
LYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPP
SLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPP
PGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL
GESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEFPLD
GRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPM
DMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKR
DYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLRGHHPGWPPEE

--------------------------------------------------------------
>100034_100034_6_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000325680_EPHB6_chr7_142568562_ENST00000442129_length(transcript)=3618nt_BP=3333nt
GTTTACACGCTCCGGGGCCTGTAGGCGCCGCGAGTTCCGGCTGTCGCCGTCGCCGCCGCGGCTCCTGGAGGTCGGTTGCGACGAGTAACG
GCGCCAGGACGAGCCCTGCGCCTTCTTTTTCGATATGTACCCGAATTGGGGCCGGTATGGCGGGAGCAGCCACTATCCGCCGCCACCGGT
CCCACCGCCGCCGCCAGTGGCGCTTCCTGAGGCCTCGCCGGGGCCCGGGTACTCGAGCTCGACGACTCCCGCGGCCCCCTCCTCCTCGGG
CTTCATGAGCTTCCGCGAACAGCACTTGGCGCAGCTCCAGCAGCTGCAGCAGATGCACCAGAAGCAAATGCAGTGCGTGCTTCAGCCCCA
CCACCTTCCTCCGCCCCCTCTGCCGCCCCCGCCAGTGATGCCGGGGGGCGGCTACGGAGACTGGCAGCCGCCACCGCCACCGATGCCCCC
GCCACCCGGGCCGGCCCTCAGCTATCAGAAGCAGCAGCAGTACAAACACCAGATGCTCCACCACCAACGAGACGGGCCTCCTGGTTTGGT
TCCAATGGAGCTGGAATCCCCCCCTGAATCTCCCCCTGTGCCGCCTGGGTCCTATATGCCCCCATCTCAGTCTTACATGCCCCCACCTCA
GCCGCCACCCTCTTACTACCCCCCGACCTCATCTCAGCCCTACCTGCCTCCTGCTCAGCCGTCCCCTTCGCAGTCCCCACCTTCCCAATC
CTACCTGGCGCCCACCCCTTCTTACTCATCCTCCTCCTCTTCCTCGCAATCCTATTTGAGCCATTCCCAGTCCTACTTGCCCTCTTCTCA
GGCATCTCCTTCCCGCCCCTCCCAGGGCCATTCTAAATCCCAACTACTAGCTCCACCACCACCGTCCGCCCCCCCTGGAAATAAGACAAC
TGTCCAGCAAGAGCCTTTGGAGAGTGGGGCCAAAAACAAGAGTACTGAACAGCAGCAAGCCGCCCCTGAGCCAGATCCCTCTACGATGAC
TCCACAGGAACAGCAGCAGTATTGGTATCGACAGCACTTGCTTAGTTTGCAACAGAGGACAAAAGTTCATTTGCCAGGACACAAAAAGGG
TCCTGTGGTAGCAAAGGATACACCAGAGCCGGTAAAAGAAGAAGTTACAGTACCTGCCACCAGTCAAGTTCCAGAATCTCCTTCTTCTGA
GGAGCCCCCATTGCCACCTCCAAATGAGGAAGTGCCACCTCCTCTCCCACCTGAGGAACCCCAGTCTGAGGACCCAGAAGAAGATGCCAG
GTTAAAGCAGTTGCAGGCTGCAGCAGCACACTGGCAGCAGCACCAGCAGCATCGAGTCGGTTTCCAGTATCAGGGAATAATGCAGAAGCA
CACTCAGTTACAGCAGATTCTACAACAGTATCAGCAGATTATACAGCCCCCACCACATATACAGACCATGTCTGTAGATATGCAGCTGCG
GCATTATGAGATGCAGCAGCAACAGTTTCAACATCTTTACCAAGAATGGGAGCGAGAGTTTCAGCTATGGGAGGAACAACTCCATTCCTA
TCCTCATAAAGATCAGCTTCAGGAGTATGAGAAGCAGTGGAAAACATGGCAGGGACATATGAAAGCCACTCAGAGCTATCTCCAGGAGAA
AGTCAATTCATTTCAGAACATGAAGAACCAGTATATGGGGAACATGTCAATGCCACCTCCTTTTGTTCCATATTCTCAGATGCCTCCACC
TCTACCTACAATGCCCCCTCCAGTGTTGCCTCCTTCATTGCCACCACCAGTGATGCCCCCTGCCCTCCCTGCTACAGTGCCACCACCTGG
CATGCCCCCACCTGTTATGCCACCTTCTCTACCAACCTCTGTTCCCCCACCAGGGATGCCTCCTTCTCTCTCTTCTGCAGGGCCACCACC
AGTTCTCCCCCCACCTTCCCTGTCTTCTGCAGGGCCACCACCAGTTCTTCCCCCACCATCTCTCTCTTCAACAGCACCTCCACCTGTCAT
GCCCCTCCCACCATTGTCTTCAGCTACACCTCCTCCAGGAATACCTCCCCCTGGAGTTCCACAAGGGATACCTCCTCAGTTAACAGCAGC
CCCAGTTCCACCAGCCTCCAGTTCACAGAGCTCGCAAGTTCCAGAGAAACCTAGACCAGCACTGCTTCCTACTCCTGTGTCTTTTGGTTC
TGCCCCACCGACAACTTACCATCCTCCGTTGCAATCAGCTGGTCCATCAGAACAAGTGAATTCAAAAGCTCCTTTGAGCAAGTCTGCTCT
GCCATACAGTTCATTCTCATCTGATCAAGGACTTGGGGAGTCTTCAGCTGCTCCATCTCAGCCAATCACTGCAGTGAAGGACATGCCAGT
GAGATCAGGTGGCCTGCTTCCAGATCCTCCTAGAAGTAGTTACTTGGAAAGTCCAAGAGGCCCAAGAAGATCAGATTTTGGTCGTGATAG
AGGTCCATTCAGACCAGAACCAGGAGATGGTGGGGAAAAAATGTATCCATATCACCGGGATGAGCCTCCTAGGGCTCCATGGAACCATGG
AGAAGAGCGAGGGCATGAAGAGTTTCCATTAGATGGTAGAAATGCTCCAATGGAACGAGAAAGACTCGATGACTGGGATAGAGAGAGATA
CTGGAGAGAATGTGAACGTGACTATCAAGATGATACACTAGAGCTCTATAACAGAGAGGACAGGTTCTCAGCACCACCATCTCGGTCTCA
TGATGGAGATAGGCGAGGCCCTTGGTGGGATGATTGGGAGAGAGACCAGGATATGGATGAGGACTACAATAGGGAAATGGAAAGGGACAT
GGACAGGGATGTGGATCGGATTTCAAGACCTATGGATATGTATGATAGAAGTTTGGATAATGAGTGGGACAGAGATTATGGGAGACCACT
GGATGAACAAGAATCACAGTTTCGTGAACGGGATATTCCATCTCTTCCACCTTTACCGCCCCTCCCACCTCTTCCACCTTTGGATAGATA
TCGGGATGATAGATGGAGAGAAGAAAGAAATCGAGAGCATGGGTATGATCGAGATTTCCGTGATAGGGGTGAGTTGAGGATTCGAGAGTA
TCCAGAAAGAGGAGATACATGGCGGGAAAAGCGAGATTATGTTCCTGACAGAATGGACTGGGAAAGAGAACGGTTGTCAGACAGATGGTA
CCCATCTGATGTGGATAGACATTCCCCCATGGCGGAACATATGCCCTCCTCACATCATTCCTCAGAAATGATGGGGTCCGATGCAAGCTT
AGACTCTGACCAAGGCCTTGGAGGGGTAATGGTTCTCAGTCAGAGGCAGCATGAAATCATTTTGAAAGCTGCACAAGAACTGAAAATGCT
TCGTGGGCATCACCCTGGCTGGCCACCAGAAGAAGCTGCTGCACCACATCCAGCTCCTTCAGCAACACCTGAGGCAGCAGGGCTCAGTGG
AGGTCTGAGAATGACGATACCCGTGACTCAGCCCTGGACACTGGTCCGAGAAGGGACATGTGGGACGTGAGCCGGGCTCCAACAGCCTCT
GTGAGAGATGCCCCACACCAAACCCAACCCTCCCGATGGCTGCATTCCCTGGTCCTCCGCCTCTCCACCAGCCCCCTCCTCATTAAAGGG

>100034_100034_6_YLPM1-EPHB6_YLPM1_chr14_75265473_ENST00000325680_EPHB6_chr7_142568562_ENST00000442129_length(amino acids)=1121AA_BP=1070
MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPP
VMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS
QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAK
NKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEV
PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQH
LYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPP
SLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPP
PGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL
GESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEFPLD
GRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPM
DMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKR
DYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLRGHHPGWPPEE

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Fusion Gene PPI Analysis for YLPM1-EPHB6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for YLPM1-EPHB6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for YLPM1-EPHB6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource