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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZBTB20-CMSS1 (FusionGDB2 ID:100348)

Fusion Gene Summary for ZBTB20-CMSS1

check button Fusion gene summary
Fusion gene informationFusion gene name: ZBTB20-CMSS1
Fusion gene ID: 100348
HgeneTgene
Gene symbol

ZBTB20

CMSS1

Gene ID

26137

84319

Gene namezinc finger and BTB domain containing 20cms1 ribosomal small subunit homolog
SynonymsDPZF|HOF|ODA-8S|PRIMS|ZNF288C3orf26
Cytomap

3q13.31

3q12.1

Type of geneprotein-codingprotein-coding
Descriptionzinc finger and BTB domain-containing protein 20BTB/POZ zinc finger protein DPZFdendritic cell-derived BTB/POZ zinc fingerzinc finger protein 288protein CMSS1
Modification date2020031320200313
UniProtAcc.

Q9BQ75

Ensembl transtripts involved in fusion geneENST00000357258, ENST00000393785, 
ENST00000462705, ENST00000464560, 
ENST00000471418, ENST00000474710, 
ENST00000481632, ENST00000488663, 
ENST00000489081, ENST00000496116, 
ENST00000421999, 
Fusion gene scores* DoF score49 X 36 X 18=3175211 X 9 X 9=891
# samples 6413
** MAII scorelog2(64/31752*10)=-5.63263175211247
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/891*10)=-2.77691380849347
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZBTB20 [Title/Abstract] AND CMSS1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZBTB20(114069121)-CMSS1(99865817), # samples:2
Anticipated loss of major functional domain due to fusion event.ZBTB20-CMSS1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ZBTB20-CMSS1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
ZBTB20-CMSS1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ZBTB20 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CMSS1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRCTCGA-CJ-5671-01AZBTB20chr3

114057852

-CMSS1chr3

99865817

+
ChimerDB4KIRCTCGA-CJ-5671-01AZBTB20chr3

114069121

-CMSS1chr3

99865817

+
ChimerDB4KIRCTCGA-CJ-5671-01AZBTB20chr3

114099064

-CMSS1chr3

99865817

+


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Fusion Gene ORF analysis for ZBTB20-CMSS1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000357258ENST00000489081ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000357258ENST00000496116ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000393785ENST00000489081ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000393785ENST00000496116ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000462705ENST00000489081ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000462705ENST00000496116ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000464560ENST00000489081ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000464560ENST00000496116ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000471418ENST00000489081ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000471418ENST00000496116ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000474710ENST00000489081ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000474710ENST00000489081ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5CDS-intronENST00000474710ENST00000496116ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000474710ENST00000496116ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5CDS-intronENST00000481632ENST00000489081ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5CDS-intronENST00000481632ENST00000496116ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
5UTR-3CDSENST00000357258ENST00000421999ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-3CDSENST00000393785ENST00000421999ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-3CDSENST00000462705ENST00000421999ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-3CDSENST00000464560ENST00000421999ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-3CDSENST00000471418ENST00000421999ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-3CDSENST00000481632ENST00000421999ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000357258ENST00000489081ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000357258ENST00000496116ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000393785ENST00000489081ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000393785ENST00000496116ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000462705ENST00000489081ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000462705ENST00000496116ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000464560ENST00000489081ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000464560ENST00000496116ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000471418ENST00000489081ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000471418ENST00000496116ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000481632ENST00000489081ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
5UTR-intronENST00000481632ENST00000496116ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
Frame-shiftENST00000393785ENST00000421999ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
Frame-shiftENST00000464560ENST00000421999ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
Frame-shiftENST00000471418ENST00000421999ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
Frame-shiftENST00000474710ENST00000421999ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
Frame-shiftENST00000474710ENST00000421999ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
In-frameENST00000357258ENST00000421999ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
In-frameENST00000462705ENST00000421999ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
In-frameENST00000481632ENST00000421999ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
intron-3CDSENST00000357258ENST00000421999ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-3CDSENST00000393785ENST00000421999ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-3CDSENST00000462705ENST00000421999ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-3CDSENST00000464560ENST00000421999ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-3CDSENST00000471418ENST00000421999ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-3CDSENST00000474710ENST00000421999ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-3CDSENST00000481632ENST00000421999ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-3CDSENST00000488663ENST00000421999ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-3CDSENST00000488663ENST00000421999ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
intron-3CDSENST00000488663ENST00000421999ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
intron-intronENST00000357258ENST00000489081ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000357258ENST00000496116ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000393785ENST00000489081ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000393785ENST00000496116ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000462705ENST00000489081ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000462705ENST00000496116ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000464560ENST00000489081ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000464560ENST00000496116ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000471418ENST00000489081ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000471418ENST00000496116ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000474710ENST00000489081ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000474710ENST00000496116ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000481632ENST00000489081ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000481632ENST00000496116ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000488663ENST00000489081ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000488663ENST00000489081ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
intron-intronENST00000488663ENST00000489081ZBTB20chr3

114099064

-CMSS1chr3

99865817

+
intron-intronENST00000488663ENST00000496116ZBTB20chr3

114057852

-CMSS1chr3

99865817

+
intron-intronENST00000488663ENST00000496116ZBTB20chr3

114069121

-CMSS1chr3

99865817

+
intron-intronENST00000488663ENST00000496116ZBTB20chr3

114099064

-CMSS1chr3

99865817

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000462705ZBTB20chr3114069121-ENST00000421999CMSS1chr399865817+339824075973182861
ENST00000481632ZBTB20chr3114069121-ENST00000421999CMSS1chr399865817+301620252152800861
ENST00000357258ZBTB20chr3114069121-ENST00000421999CMSS1chr399865817+319021993892974861

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000462705ENST00000421999ZBTB20chr3114069121-CMSS1chr399865817+0.0068943180.9931057
ENST00000481632ENST00000421999ZBTB20chr3114069121-CMSS1chr399865817+0.0102161080.98978394
ENST00000357258ENST00000421999ZBTB20chr3114069121-CMSS1chr399865817+0.007938690.9920614

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Fusion Genomic Features for ZBTB20-CMSS1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZBTB20chr3114069120-CMSS1chr399865816+0.000113420.9998865
ZBTB20chr3114099063-CMSS1chr399865816+4.85E-050.9999515
ZBTB20chr3114069120-CMSS1chr399865816+0.000113420.9998865
ZBTB20chr3114099063-CMSS1chr399865816+4.85E-050.9999515

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZBTB20-CMSS1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:114069121/chr3:99865817)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CMSS1

Q9BQ75

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZBTB20chr3:114069121chr3:99865817ENST00000357258-910104_167528669.0DomainBTB
HgeneZBTB20chr3:114069121chr3:99865817ENST00000393785-56104_167528669.0DomainBTB
HgeneZBTB20chr3:114069121chr3:99865817ENST00000462705-1112104_167528669.0DomainBTB
HgeneZBTB20chr3:114069121chr3:99865817ENST00000464560-78104_167528669.0DomainBTB
HgeneZBTB20chr3:114069121chr3:99865817ENST00000471418-67104_167528669.0DomainBTB
HgeneZBTB20chr3:114069121chr3:99865817ENST00000474710-45104_167601742.0DomainBTB
HgeneZBTB20chr3:114069121chr3:99865817ENST00000481632-56104_167528669.0DomainBTB
HgeneZBTB20chr3:114069121chr3:99865817ENST00000474710-45578_600601742.0Zinc fingerC2H2-type 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZBTB20chr3:114069121chr3:99865817ENST00000357258-910578_600528669.0Zinc fingerC2H2-type 1
HgeneZBTB20chr3:114069121chr3:99865817ENST00000357258-910606_628528669.0Zinc fingerC2H2-type 2
HgeneZBTB20chr3:114069121chr3:99865817ENST00000357258-910634_656528669.0Zinc fingerC2H2-type 3
HgeneZBTB20chr3:114069121chr3:99865817ENST00000357258-910662_684528669.0Zinc fingerC2H2-type 4
HgeneZBTB20chr3:114069121chr3:99865817ENST00000357258-910715_737528669.0Zinc fingerC2H2-type 5
HgeneZBTB20chr3:114069121chr3:99865817ENST00000393785-56578_600528669.0Zinc fingerC2H2-type 1
HgeneZBTB20chr3:114069121chr3:99865817ENST00000393785-56606_628528669.0Zinc fingerC2H2-type 2
HgeneZBTB20chr3:114069121chr3:99865817ENST00000393785-56634_656528669.0Zinc fingerC2H2-type 3
HgeneZBTB20chr3:114069121chr3:99865817ENST00000393785-56662_684528669.0Zinc fingerC2H2-type 4
HgeneZBTB20chr3:114069121chr3:99865817ENST00000393785-56715_737528669.0Zinc fingerC2H2-type 5
HgeneZBTB20chr3:114069121chr3:99865817ENST00000462705-1112578_600528669.0Zinc fingerC2H2-type 1
HgeneZBTB20chr3:114069121chr3:99865817ENST00000462705-1112606_628528669.0Zinc fingerC2H2-type 2
HgeneZBTB20chr3:114069121chr3:99865817ENST00000462705-1112634_656528669.0Zinc fingerC2H2-type 3
HgeneZBTB20chr3:114069121chr3:99865817ENST00000462705-1112662_684528669.0Zinc fingerC2H2-type 4
HgeneZBTB20chr3:114069121chr3:99865817ENST00000462705-1112715_737528669.0Zinc fingerC2H2-type 5
HgeneZBTB20chr3:114069121chr3:99865817ENST00000464560-78578_600528669.0Zinc fingerC2H2-type 1
HgeneZBTB20chr3:114069121chr3:99865817ENST00000464560-78606_628528669.0Zinc fingerC2H2-type 2
HgeneZBTB20chr3:114069121chr3:99865817ENST00000464560-78634_656528669.0Zinc fingerC2H2-type 3
HgeneZBTB20chr3:114069121chr3:99865817ENST00000464560-78662_684528669.0Zinc fingerC2H2-type 4
HgeneZBTB20chr3:114069121chr3:99865817ENST00000464560-78715_737528669.0Zinc fingerC2H2-type 5
HgeneZBTB20chr3:114069121chr3:99865817ENST00000471418-67578_600528669.0Zinc fingerC2H2-type 1
HgeneZBTB20chr3:114069121chr3:99865817ENST00000471418-67606_628528669.0Zinc fingerC2H2-type 2
HgeneZBTB20chr3:114069121chr3:99865817ENST00000471418-67634_656528669.0Zinc fingerC2H2-type 3
HgeneZBTB20chr3:114069121chr3:99865817ENST00000471418-67662_684528669.0Zinc fingerC2H2-type 4
HgeneZBTB20chr3:114069121chr3:99865817ENST00000471418-67715_737528669.0Zinc fingerC2H2-type 5
HgeneZBTB20chr3:114069121chr3:99865817ENST00000474710-45606_628601742.0Zinc fingerC2H2-type 2
HgeneZBTB20chr3:114069121chr3:99865817ENST00000474710-45634_656601742.0Zinc fingerC2H2-type 3
HgeneZBTB20chr3:114069121chr3:99865817ENST00000474710-45662_684601742.0Zinc fingerC2H2-type 4
HgeneZBTB20chr3:114069121chr3:99865817ENST00000474710-45715_737601742.0Zinc fingerC2H2-type 5
HgeneZBTB20chr3:114069121chr3:99865817ENST00000481632-56578_600528669.0Zinc fingerC2H2-type 1
HgeneZBTB20chr3:114069121chr3:99865817ENST00000481632-56606_628528669.0Zinc fingerC2H2-type 2
HgeneZBTB20chr3:114069121chr3:99865817ENST00000481632-56634_656528669.0Zinc fingerC2H2-type 3
HgeneZBTB20chr3:114069121chr3:99865817ENST00000481632-56662_684528669.0Zinc fingerC2H2-type 4
HgeneZBTB20chr3:114069121chr3:99865817ENST00000481632-56715_737528669.0Zinc fingerC2H2-type 5


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Fusion Gene Sequence for ZBTB20-CMSS1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>100348_100348_1_ZBTB20-CMSS1_ZBTB20_chr3_114069121_ENST00000357258_CMSS1_chr3_99865817_ENST00000421999_length(transcript)=3190nt_BP=2199nt
GGGGCGGGGGGAAGTTTAGGAGTTGAGGAAAGAAGATTAAAGAGCGCGAGGAGACAAATAAAAAGAAGTGTTAAGAATTGCCTTTGGGAC
TCTGAAGGCTGAAGAATTGATGAATTGCAAGTTTGTGCCCCATAGCTGCACAGACTGCCTGAAGTTACATTTAGAGACTGAAATCACTGC
ACCTTAAAAACAAAAGATTGAGCTGCACTGTATTCCTAATGTTTCATCATTACTAACAGGATATTCCTCATGACATTGCTGTCTGATCTT
TGACCATCAGTCTGTGACCTGCCCCTTCTCTTTACATGCAGCCGCTCTCTGCTCCCTGCCCCAATGAACATCTGCACTAGGCCCAAGCCT
TGGAGTAATTTACCTGAAGAGTGACACCATTGATTTTGAAACTACTGAAGAAACCCAAGACAGCTGAAAACCAGAAGGCATCTGAGGAGA
ATGAGATTACTCAGCCGGGTGGATCCAGCGCCAAGCCGGGCCTTCCCTGCCTGAACTTTGAAGCTGTTTTGTCTCCAGACCCAGCCCTCA
TCCACTCAACACATTCACTGACAAACTCTCACGCTCACACCGGGTCATCTGATTGTGACATCAGTTGCAAGGGGATGACCGAGCGCATTC
ACAGCATCAACCTTCACAACTTCAGCAATTCCGTGCTCGAGACCCTCAACGAGCAGCGCAACCGTGGCCACTTCTGTGACGTAACGGTGC
GCATCCACGGGAGCATGCTGCGCGCACACCGCTGCGTGCTGGCAGCCGGCAGCCCCTTCTTCCAGGACAAACTGCTGCTTGGCTACAGCG
ACATCGAGATCCCGTCGGTGGTGTCAGTGCAGTCAGTGCAAAAGCTCATTGACTTCATGTACAGCGGCGTGCTACGGGTCTCGCAGTCGG
AAGCTCTGCAGATCCTCACGGCCGCCAGCATCCTGCAGATCAAAACAGTCATCGACGAGTGCACGCGCATCGTGTCACAGAACGTGGGCG
ATGTGTTCCCGGGGATCCAGGACTCGGGCCAGGACACGCCGCGGGGCACTCCCGAGTCAGGCACGTCAGGCCAGAGCAGCGACACGGAGT
CGGGCTACCTGCAGAGCCACCCACAGCACAGCGTGGACAGGATCTACTCGGCACTCTACGCGTGCTCCATGCAGAATGGCAGCGGCGAGC
GCTCTTTTTACAGCGGCGCAGTGGTCAGCCACCACGAGACTGCGCTCGGCCTGCCCCGCGACCACCACATGGAAGACCCCAGCTGGATCA
CACGCATCCATGAGCGCTCGCAGCAGATGGAGCGCTACCTGTCCACCACCCCCGAGACCACGCACTGCCGCAAGCAGCCCCGGCCTGTGC
GCATCCAGACCCTAGTGGGCAACATCCACATCAAGCAGGAGATGGAGGACGATTACGACTACTACGGGCAGCAAAGGGTGCAGATCCTGG
AACGCAACGAATCCGAGGAGTGCACGGAAGACACAGACCAGGCCGAGGGCACCGAGAGTGAGCCCAAAGGTGAAAGCTTCGACTCGGGCG
TCAGCTCCTCCATAGGCACCGAGCCTGACTCGGTGGAGCAGCAGTTTGGGCCTGGGGCGGCGCGGGACAGCCAGGCTGAACCCACCCAAC
CCGAGCAGGCTGCAGAAGCCCCCGCTGAGGGTGGTCCGCAGACAAACCAGCTAGAAACAGGTGCTTCCTCTCCGGAGAGAAGCAATGAAG
TGGAGATGGACAGCACTGTTATCACTGTCAGCAACAGCTCCGACAAGAGCGTCCTACAACAGCCTTCGGTCAACACGTCCATCGGGCAGC
CATTGCCAAGTACCCAGCTCTACTTACGCCAGACAGAAACCCTCACCAGCAACCTGAGGATGCCTCTGACCTTGACCAGCAACACGCAGG
TCATTGGCACAGCTGGCAACACCTACCTGCCAGCCCTCTTCACTACCCAGCCCGCGGGCAGTGGCCCCAAGCCTTTCCTCTTCAGCCTGC
CACAGCCCCTGGCAGGCCAGCAGACCCAGTTTGTGACAGTGTCCCAGCCCGGTCTGTCGACCTTTACTGCACAGCTGCCAGCGCCACAGC
CCCTGGCCTCATCCGCAGGCCACAGCACAGCCAGTGGGCAAGGCGAAAAAAAGCCTTATGAGTGCACTCTCTGCAACAAGACTTTCACCG
CCAAACAGAACTACGTCAAGCACATGTTCGTACACACAGAAGCATCAGATGGTGAAGGAGAAGGAGACACAGAAGTGATGCAGCAGGAGA
CAGTTCCAGTTCCTGTACCTTCAGAGAAAACCAAACAGCCTAAAGAATGTTTTTTGATACAACCAAAGGAAAGAAAAGAGAATACCACCA
AGACCAGGAAAAGAAGAAAGAAGAAAATTACTGATGTTCTTGCAAAATCAGAACCAAAACCAGGGTTACCTGAAGACCTACAGAAGCTGA
TGAAGGACTATTATAGCAGCAGACGCTTGGTGATTGAATTAGAAGAACTGAACCTGCCAGACTCCTGTTTCCTCAAGGCCAATGATTTGA
CTCACAGTCTTTCCTCATACCTAAAAGAAATTTGTCCTAAGTGGGTAAAACTTAGGAAGAACCACAGTGAGAAGAAATCGGTCCTGATGC
TGATCATCTGCAGCTCGGCCGTCCGAGCCCTGGAGCTCATTAGGTCGATGACAGCATTCAGAGGAGACGGCAAAGTTATAAAATTATTTG
CAAAGCACATAAAGGTCCAGGCGCAGGTAAAGTTGCTGGAGAAGCGTGTGGTGCACCTGGGTGTAGGAACTCCGGGGAGAATTAAAGAAC
TTGTTAAACAAGGTGGCCTTAATTTGAGCCCCTTAAAATTTCTGGTTTTTGACTGGAACTGGAGAGATCAGAAGTTGAGGAGAATGATGG
ACATTCCCGAGATAAGAAAGGAGGTATTCGAACTTCTGGAAATGGGAGTGCTCAGTCTGTGCAAGTCAGAATCCTTGAAACTGGGCCTTT
TCTAAGTCTGTGTCCTAATGAAGATTCCAGTTTTCACAGTAGAAGTTGCATCTTATTTAATGACTCTGATACATTGCAAGCACTCAGTAA
ATATCAGCAAATAGTTTATGTTAATTGTGTCAACAGATGGATCACTGGAATGTGGGGATTCTGAAACAGAAATGAAACTGTCCTTTTGAC

>100348_100348_1_ZBTB20-CMSS1_ZBTB20_chr3_114069121_ENST00000357258_CMSS1_chr3_99865817_ENST00000421999_length(amino acids)=861AA_BP=603
MILKLLKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSN
SVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAAS
ILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVS
HHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTE
DTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPGAARDSQAEPTQPEQAAEAPAEGGPQTNQLETGASSPERSNEVEMDSTVITV
SNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQ
FVTVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTEASDGEGEGDTEVMQQETVPVPVPSEK
TKQPKECFLIQPKERKENTTKTRKRRKKKITDVLAKSEPKPGLPEDLQKLMKDYYSSRRLVIELEELNLPDSCFLKANDLTHSLSSYLKE
ICPKWVKLRKNHSEKKSVLMLIICSSAVRALELIRSMTAFRGDGKVIKLFAKHIKVQAQVKLLEKRVVHLGVGTPGRIKELVKQGGLNLS

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>100348_100348_2_ZBTB20-CMSS1_ZBTB20_chr3_114069121_ENST00000462705_CMSS1_chr3_99865817_ENST00000421999_length(transcript)=3398nt_BP=2407nt
GGAATTTTATCTCTGCTCACAGTCTACATTACAACATTAGTTCATTCTGGGCACTTTAGCTTCCTTGAATCTCCAGTTGATCTCACACCC
ATGCCTATGATATTCTTCTCCTGGTTAATCAAGAATTCTCTATTTCTGCTCCGTCATCCATGCCACTACAAATAAAAAGAAGTGTTAAGA
ATTGCCTTTGGGACTCTGAAGGCTGAAGAATTGATGAATTGCAAGTTTGTGCCCCATAGCTGCACAGCCTATGTCTAAGCACAGCTCATC
TTCACAAACTGAAGTGGATCTTGATTTCTGGAAATGTCCAAATAATGACAACAACCCCATGGAGGTGGATACATCAGAGTCAGCTGGAGG
TGGTCAGAATTATTTGCAATGTTTGGGAAAGCACCTACCAAGGCTTCCTATTACCTATTTCACAGAATGTTTCATCATTACTAACAGGAT
ATTCCTCATGACATTGCTGTCTGATCTTTGACCATCAGTCTGTGACCTGCCCCTTCTCTTTACATGCAGCCGCTCTCTGCTCCCTGCCCC
AATGAACATCTGCACTAGGCCCAAGCCTTGGAGTAATTTACCTGAAGAGTGACACCATTGATTTTGAAACTACTGAAGAAACCCAAGACA
GCTGAAAACCAGAAGGCATCTGAGGAGAATGAGATTACTCAGCCGGGTGGATCCAGCGCCAAGCCGGGCCTTCCCTGCCTGAACTTTGAA
GCTGTTTTGTCTCCAGACCCAGCCCTCATCCACTCAACACATTCACTGACAAACTCTCACGCTCACACCGGGTCATCTGATTGTGACATC
AGTTGCAAGGGGATGACCGAGCGCATTCACAGCATCAACCTTCACAACTTCAGCAATTCCGTGCTCGAGACCCTCAACGAGCAGCGCAAC
CGTGGCCACTTCTGTGACGTAACGGTGCGCATCCACGGGAGCATGCTGCGCGCACACCGCTGCGTGCTGGCAGCCGGCAGCCCCTTCTTC
CAGGACAAACTGCTGCTTGGCTACAGCGACATCGAGATCCCGTCGGTGGTGTCAGTGCAGTCAGTGCAAAAGCTCATTGACTTCATGTAC
AGCGGCGTGCTACGGGTCTCGCAGTCGGAAGCTCTGCAGATCCTCACGGCCGCCAGCATCCTGCAGATCAAAACAGTCATCGACGAGTGC
ACGCGCATCGTGTCACAGAACGTGGGCGATGTGTTCCCGGGGATCCAGGACTCGGGCCAGGACACGCCGCGGGGCACTCCCGAGTCAGGC
ACGTCAGGCCAGAGCAGCGACACGGAGTCGGGCTACCTGCAGAGCCACCCACAGCACAGCGTGGACAGGATCTACTCGGCACTCTACGCG
TGCTCCATGCAGAATGGCAGCGGCGAGCGCTCTTTTTACAGCGGCGCAGTGGTCAGCCACCACGAGACTGCGCTCGGCCTGCCCCGCGAC
CACCACATGGAAGACCCCAGCTGGATCACACGCATCCATGAGCGCTCGCAGCAGATGGAGCGCTACCTGTCCACCACCCCCGAGACCACG
CACTGCCGCAAGCAGCCCCGGCCTGTGCGCATCCAGACCCTAGTGGGCAACATCCACATCAAGCAGGAGATGGAGGACGATTACGACTAC
TACGGGCAGCAAAGGGTGCAGATCCTGGAACGCAACGAATCCGAGGAGTGCACGGAAGACACAGACCAGGCCGAGGGCACCGAGAGTGAG
CCCAAAGGTGAAAGCTTCGACTCGGGCGTCAGCTCCTCCATAGGCACCGAGCCTGACTCGGTGGAGCAGCAGTTTGGGCCTGGGGCGGCG
CGGGACAGCCAGGCTGAACCCACCCAACCCGAGCAGGCTGCAGAAGCCCCCGCTGAGGGTGGTCCGCAGACAAACCAGCTAGAAACAGGT
GCTTCCTCTCCGGAGAGAAGCAATGAAGTGGAGATGGACAGCACTGTTATCACTGTCAGCAACAGCTCCGACAAGAGCGTCCTACAACAG
CCTTCGGTCAACACGTCCATCGGGCAGCCATTGCCAAGTACCCAGCTCTACTTACGCCAGACAGAAACCCTCACCAGCAACCTGAGGATG
CCTCTGACCTTGACCAGCAACACGCAGGTCATTGGCACAGCTGGCAACACCTACCTGCCAGCCCTCTTCACTACCCAGCCCGCGGGCAGT
GGCCCCAAGCCTTTCCTCTTCAGCCTGCCACAGCCCCTGGCAGGCCAGCAGACCCAGTTTGTGACAGTGTCCCAGCCCGGTCTGTCGACC
TTTACTGCACAGCTGCCAGCGCCACAGCCCCTGGCCTCATCCGCAGGCCACAGCACAGCCAGTGGGCAAGGCGAAAAAAAGCCTTATGAG
TGCACTCTCTGCAACAAGACTTTCACCGCCAAACAGAACTACGTCAAGCACATGTTCGTACACACAGAAGCATCAGATGGTGAAGGAGAA
GGAGACACAGAAGTGATGCAGCAGGAGACAGTTCCAGTTCCTGTACCTTCAGAGAAAACCAAACAGCCTAAAGAATGTTTTTTGATACAA
CCAAAGGAAAGAAAAGAGAATACCACCAAGACCAGGAAAAGAAGAAAGAAGAAAATTACTGATGTTCTTGCAAAATCAGAACCAAAACCA
GGGTTACCTGAAGACCTACAGAAGCTGATGAAGGACTATTATAGCAGCAGACGCTTGGTGATTGAATTAGAAGAACTGAACCTGCCAGAC
TCCTGTTTCCTCAAGGCCAATGATTTGACTCACAGTCTTTCCTCATACCTAAAAGAAATTTGTCCTAAGTGGGTAAAACTTAGGAAGAAC
CACAGTGAGAAGAAATCGGTCCTGATGCTGATCATCTGCAGCTCGGCCGTCCGAGCCCTGGAGCTCATTAGGTCGATGACAGCATTCAGA
GGAGACGGCAAAGTTATAAAATTATTTGCAAAGCACATAAAGGTCCAGGCGCAGGTAAAGTTGCTGGAGAAGCGTGTGGTGCACCTGGGT
GTAGGAACTCCGGGGAGAATTAAAGAACTTGTTAAACAAGGTGGCCTTAATTTGAGCCCCTTAAAATTTCTGGTTTTTGACTGGAACTGG
AGAGATCAGAAGTTGAGGAGAATGATGGACATTCCCGAGATAAGAAAGGAGGTATTCGAACTTCTGGAAATGGGAGTGCTCAGTCTGTGC
AAGTCAGAATCCTTGAAACTGGGCCTTTTCTAAGTCTGTGTCCTAATGAAGATTCCAGTTTTCACAGTAGAAGTTGCATCTTATTTAATG
ACTCTGATACATTGCAAGCACTCAGTAAATATCAGCAAATAGTTTATGTTAATTGTGTCAACAGATGGATCACTGGAATGTGGGGATTCT

>100348_100348_2_ZBTB20-CMSS1_ZBTB20_chr3_114069121_ENST00000462705_CMSS1_chr3_99865817_ENST00000421999_length(amino acids)=861AA_BP=603
MILKLLKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSN
SVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAAS
ILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVS
HHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTE
DTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPGAARDSQAEPTQPEQAAEAPAEGGPQTNQLETGASSPERSNEVEMDSTVITV
SNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQ
FVTVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTEASDGEGEGDTEVMQQETVPVPVPSEK
TKQPKECFLIQPKERKENTTKTRKRRKKKITDVLAKSEPKPGLPEDLQKLMKDYYSSRRLVIELEELNLPDSCFLKANDLTHSLSSYLKE
ICPKWVKLRKNHSEKKSVLMLIICSSAVRALELIRSMTAFRGDGKVIKLFAKHIKVQAQVKLLEKRVVHLGVGTPGRIKELVKQGGLNLS

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>100348_100348_3_ZBTB20-CMSS1_ZBTB20_chr3_114069121_ENST00000481632_CMSS1_chr3_99865817_ENST00000421999_length(transcript)=3016nt_BP=2025nt
GCAGGGAGCTTAACAGCCAGGCCTGGACACCCTCAAGAGACTGTGTGCTGATTCTCAGTCGTCACTCCTTGGATCAGGAACCATAGTCCT
GATCTTTGACCATCAGTCTGTGACCTGCCCCTTCTCTTTACATGCAGCCGCTCTCTGCTCCCTGCCCCAATGAACATCTGCACTAGGCCC
AAGCCTTGGAGTAATTTACCTGAAGAGTGACACCATTGATTTTGAAACTACTGAAGAAACCCAAGACAGCTGAAAACCAGAAGGCATCTG
AGGAGAATGAGATTACTCAGCCGGGTGGATCCAGCGCCAAGCCGGGCCTTCCCTGCCTGAACTTTGAAGCTGTTTTGTCTCCAGACCCAG
CCCTCATCCACTCAACACATTCACTGACAAACTCTCACGCTCACACCGGGTCATCTGATTGTGACATCAGTTGCAAGGGGATGACCGAGC
GCATTCACAGCATCAACCTTCACAACTTCAGCAATTCCGTGCTCGAGACCCTCAACGAGCAGCGCAACCGTGGCCACTTCTGTGACGTAA
CGGTGCGCATCCACGGGAGCATGCTGCGCGCACACCGCTGCGTGCTGGCAGCCGGCAGCCCCTTCTTCCAGGACAAACTGCTGCTTGGCT
ACAGCGACATCGAGATCCCGTCGGTGGTGTCAGTGCAGTCAGTGCAAAAGCTCATTGACTTCATGTACAGCGGCGTGCTACGGGTCTCGC
AGTCGGAAGCTCTGCAGATCCTCACGGCCGCCAGCATCCTGCAGATCAAAACAGTCATCGACGAGTGCACGCGCATCGTGTCACAGAACG
TGGGCGATGTGTTCCCGGGGATCCAGGACTCGGGCCAGGACACGCCGCGGGGCACTCCCGAGTCAGGCACGTCAGGCCAGAGCAGCGACA
CGGAGTCGGGCTACCTGCAGAGCCACCCACAGCACAGCGTGGACAGGATCTACTCGGCACTCTACGCGTGCTCCATGCAGAATGGCAGCG
GCGAGCGCTCTTTTTACAGCGGCGCAGTGGTCAGCCACCACGAGACTGCGCTCGGCCTGCCCCGCGACCACCACATGGAAGACCCCAGCT
GGATCACACGCATCCATGAGCGCTCGCAGCAGATGGAGCGCTACCTGTCCACCACCCCCGAGACCACGCACTGCCGCAAGCAGCCCCGGC
CTGTGCGCATCCAGACCCTAGTGGGCAACATCCACATCAAGCAGGAGATGGAGGACGATTACGACTACTACGGGCAGCAAAGGGTGCAGA
TCCTGGAACGCAACGAATCCGAGGAGTGCACGGAAGACACAGACCAGGCCGAGGGCACCGAGAGTGAGCCCAAAGGTGAAAGCTTCGACT
CGGGCGTCAGCTCCTCCATAGGCACCGAGCCTGACTCGGTGGAGCAGCAGTTTGGGCCTGGGGCGGCGCGGGACAGCCAGGCTGAACCCA
CCCAACCCGAGCAGGCTGCAGAAGCCCCCGCTGAGGGTGGTCCGCAGACAAACCAGCTAGAAACAGGTGCTTCCTCTCCGGAGAGAAGCA
ATGAAGTGGAGATGGACAGCACTGTTATCACTGTCAGCAACAGCTCCGACAAGAGCGTCCTACAACAGCCTTCGGTCAACACGTCCATCG
GGCAGCCATTGCCAAGTACCCAGCTCTACTTACGCCAGACAGAAACCCTCACCAGCAACCTGAGGATGCCTCTGACCTTGACCAGCAACA
CGCAGGTCATTGGCACAGCTGGCAACACCTACCTGCCAGCCCTCTTCACTACCCAGCCCGCGGGCAGTGGCCCCAAGCCTTTCCTCTTCA
GCCTGCCACAGCCCCTGGCAGGCCAGCAGACCCAGTTTGTGACAGTGTCCCAGCCCGGTCTGTCGACCTTTACTGCACAGCTGCCAGCGC
CACAGCCCCTGGCCTCATCCGCAGGCCACAGCACAGCCAGTGGGCAAGGCGAAAAAAAGCCTTATGAGTGCACTCTCTGCAACAAGACTT
TCACCGCCAAACAGAACTACGTCAAGCACATGTTCGTACACACAGAAGCATCAGATGGTGAAGGAGAAGGAGACACAGAAGTGATGCAGC
AGGAGACAGTTCCAGTTCCTGTACCTTCAGAGAAAACCAAACAGCCTAAAGAATGTTTTTTGATACAACCAAAGGAAAGAAAAGAGAATA
CCACCAAGACCAGGAAAAGAAGAAAGAAGAAAATTACTGATGTTCTTGCAAAATCAGAACCAAAACCAGGGTTACCTGAAGACCTACAGA
AGCTGATGAAGGACTATTATAGCAGCAGACGCTTGGTGATTGAATTAGAAGAACTGAACCTGCCAGACTCCTGTTTCCTCAAGGCCAATG
ATTTGACTCACAGTCTTTCCTCATACCTAAAAGAAATTTGTCCTAAGTGGGTAAAACTTAGGAAGAACCACAGTGAGAAGAAATCGGTCC
TGATGCTGATCATCTGCAGCTCGGCCGTCCGAGCCCTGGAGCTCATTAGGTCGATGACAGCATTCAGAGGAGACGGCAAAGTTATAAAAT
TATTTGCAAAGCACATAAAGGTCCAGGCGCAGGTAAAGTTGCTGGAGAAGCGTGTGGTGCACCTGGGTGTAGGAACTCCGGGGAGAATTA
AAGAACTTGTTAAACAAGGTGGCCTTAATTTGAGCCCCTTAAAATTTCTGGTTTTTGACTGGAACTGGAGAGATCAGAAGTTGAGGAGAA
TGATGGACATTCCCGAGATAAGAAAGGAGGTATTCGAACTTCTGGAAATGGGAGTGCTCAGTCTGTGCAAGTCAGAATCCTTGAAACTGG
GCCTTTTCTAAGTCTGTGTCCTAATGAAGATTCCAGTTTTCACAGTAGAAGTTGCATCTTATTTAATGACTCTGATACATTGCAAGCACT
CAGTAAATATCAGCAAATAGTTTATGTTAATTGTGTCAACAGATGGATCACTGGAATGTGGGGATTCTGAAACAGAAATGAAACTGTCCT

>100348_100348_3_ZBTB20-CMSS1_ZBTB20_chr3_114069121_ENST00000481632_CMSS1_chr3_99865817_ENST00000421999_length(amino acids)=861AA_BP=603
MILKLLKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSN
SVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAAS
ILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVS
HHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTE
DTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPGAARDSQAEPTQPEQAAEAPAEGGPQTNQLETGASSPERSNEVEMDSTVITV
SNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQ
FVTVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTEASDGEGEGDTEVMQQETVPVPVPSEK
TKQPKECFLIQPKERKENTTKTRKRRKKKITDVLAKSEPKPGLPEDLQKLMKDYYSSRRLVIELEELNLPDSCFLKANDLTHSLSSYLKE
ICPKWVKLRKNHSEKKSVLMLIICSSAVRALELIRSMTAFRGDGKVIKLFAKHIKVQAQVKLLEKRVVHLGVGTPGRIKELVKQGGLNLS

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Fusion Gene PPI Analysis for ZBTB20-CMSS1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZBTB20-CMSS1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZBTB20-CMSS1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource