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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZCCHC7-MLLT3 (FusionGDB2 ID:100703)

Fusion Gene Summary for ZCCHC7-MLLT3

check button Fusion gene summary
Fusion gene informationFusion gene name: ZCCHC7-MLLT3
Fusion gene ID: 100703
HgeneTgene
Gene symbol

ZCCHC7

MLLT3

Gene ID

84186

4300

Gene namezinc finger CCHC-type containing 7MLLT3 super elongation complex subunit
SynonymsAIR1|HSPC086AF9|YEATS3
Cytomap

9p13.2

9p21.3

Type of geneprotein-codingprotein-coding
Descriptionzinc finger CCHC domain-containing protein 7TRAMP-like complex RNA-binding factor ZCCHC7zinc finger, CCHC domain containing 7protein AF-9ALL1-fused gene from chromosome 9 proteinKMT2A/MLLT3 fusionKMT2A/MLLT3 fusion proteinYEATS domain-containing protein 3myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 3myeloid/lymphoid or mixed-lineage leu
Modification date2020032020200327
UniProtAcc.

P42568

Ensembl transtripts involved in fusion geneENST00000461038, ENST00000322831, 
ENST00000336755, ENST00000534928, 
ENST00000380338, ENST00000355930, 
ENST00000429426, ENST00000380321, 
ENST00000475957, 
Fusion gene scores* DoF score29 X 11 X 11=350918 X 37 X 9=5994
# samples 2935
** MAII scorelog2(29/3509*10)=-3.59693514238723
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(35/5994*10)=-4.09809225668125
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZCCHC7 [Title/Abstract] AND MLLT3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZCCHC7(37126939)-MLLT3(20456784), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMLLT3

GO:0045893

positive regulation of transcription, DNA-templated

25417107|27105114

TgeneMLLT3

GO:0090090

negative regulation of canonical Wnt signaling pathway

19591803


check buttonFusion gene breakpoints across ZCCHC7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MLLT3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-6709-01AZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
ChimerDB4STADTCGA-BR-6709ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-


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Fusion Gene ORF analysis for ZCCHC7-MLLT3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000461038ENST00000380338ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
3UTR-5UTRENST00000461038ENST00000355930ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
3UTR-5UTRENST00000461038ENST00000429426ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
3UTR-intronENST00000461038ENST00000380321ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
3UTR-intronENST00000461038ENST00000475957ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
5CDS-5UTRENST00000322831ENST00000355930ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
5CDS-5UTRENST00000322831ENST00000429426ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
5CDS-5UTRENST00000336755ENST00000355930ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
5CDS-5UTRENST00000336755ENST00000429426ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
5CDS-intronENST00000322831ENST00000380321ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
5CDS-intronENST00000322831ENST00000475957ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
5CDS-intronENST00000336755ENST00000380321ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
5CDS-intronENST00000336755ENST00000475957ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
In-frameENST00000322831ENST00000380338ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
In-frameENST00000336755ENST00000380338ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
intron-3CDSENST00000534928ENST00000380338ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
intron-5UTRENST00000534928ENST00000355930ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
intron-5UTRENST00000534928ENST00000429426ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
intron-intronENST00000534928ENST00000380321ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-
intron-intronENST00000534928ENST00000475957ZCCHC7chr9

37126939

+MLLT3chr9

20456784

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000336755ZCCHC7chr937126939+ENST00000380338MLLT3chr920456784-70087161062229707
ENST00000322831ZCCHC7chr937126939+ENST00000380338MLLT3chr920456784-71688762662389707

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000336755ENST00000380338ZCCHC7chr937126939+MLLT3chr920456784-0.0002522630.9997477
ENST00000322831ENST00000380338ZCCHC7chr937126939+MLLT3chr920456784-0.0002677610.9997322

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Fusion Genomic Features for ZCCHC7-MLLT3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZCCHC7-MLLT3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:37126939/chr9:20456784)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MLLT3

P42568

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA (PubMed:20159561, PubMed:20471948, PubMed:25417107, PubMed:27105114, PubMed:27545619). Specifically recognizes and binds acylated histone H3, with a preference for histone H3 that is crotonylated (PubMed:25417107, PubMed:27105114, PubMed:27545619, PubMed:30374167, PubMed:30385749). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors (PubMed:25417107, PubMed:27105114, PubMed:27545619). Recognizes and binds histone H3 crotonylated at 'Lys-9' (H3K9cr), and with slightly lower affinity histone H3 crotonylated at 'Lys-18' (H3K18cr) (PubMed:27105114). Also recognizes and binds histone H3 acetylated and butyrylated at 'Lys-9' (H3K9ac and H3K9bu, respectively), but with lower affinity than crotonylated histone H3 (PubMed:25417107, PubMed:27105114, PubMed:30385749). In the SEC complex, MLLT3 is required to recruit the complex to crotonylated histones (PubMed:27105114, PubMed:27545619). Recruitment of the SEC complex to crotonylated histones promotes recruitment of DOT1L on active chromatin to deposit histone H3 'Lys-79' methylation (H3K79me) (PubMed:25417107). Plays a key role in hematopoietic stem cell (HSC) maintenance by preserving, rather than confering, HSC stemness (PubMed:31776511). Acts by binding to the transcription start site of active genes in HSCs and sustaining level of H3K79me2, probably by recruiting DOT1L (PubMed:31776511). {ECO:0000269|PubMed:20159561, ECO:0000269|PubMed:20471948, ECO:0000269|PubMed:25417107, ECO:0000269|PubMed:27105114, ECO:0000269|PubMed:27545619, ECO:0000269|PubMed:30374167, ECO:0000269|PubMed:30385749, ECO:0000269|PubMed:31776511}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMLLT3chr9:37126939chr9:20456784ENST00000380338111149_19464569.0Compositional biasNote=Poly-Ser
TgeneMLLT3chr9:37126939chr9:20456784ENST00000380338111383_39164569.0Compositional biasNote=Poly-Ser
TgeneMLLT3chr9:37126939chr9:20456784ENST00000380338111466_46964569.0Compositional biasNote=Poly-Pro
TgeneMLLT3chr9:37126939chr9:20456784ENST00000380338111295_30064569.0MotifNuclear localization signal
TgeneMLLT3chr9:37126939chr9:20456784ENST00000380338111106_10864569.0RegionHistone H3K9cr binding
TgeneMLLT3chr9:37126939chr9:20456784ENST00000380338111106_10964569.0RegionInhibitor XL-07i binding
TgeneMLLT3chr9:37126939chr9:20456784ENST0000038033811178_8064569.0RegionHistone H3K9cr binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZCCHC7chr9:37126939chr9:20456784ENST00000336755+29241_258203544.0Zinc fingerCCHC-type 1
HgeneZCCHC7chr9:37126939chr9:20456784ENST00000336755+29263_280203544.0Zinc fingerCCHC-type 2
HgeneZCCHC7chr9:37126939chr9:20456784ENST00000336755+29304_321203544.0Zinc fingerCCHC-type 3
HgeneZCCHC7chr9:37126939chr9:20456784ENST00000336755+29348_365203544.0Zinc fingerCCHC-type 4
TgeneMLLT3chr9:37126939chr9:20456784ENST000003803381111_13864569.0DomainYEATS
TgeneMLLT3chr9:37126939chr9:20456784ENST0000038033811156_5864569.0RegionInhibitor XL-07i binding


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Fusion Gene Sequence for ZCCHC7-MLLT3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>100703_100703_1_ZCCHC7-MLLT3_ZCCHC7_chr9_37126939_ENST00000322831_MLLT3_chr9_20456784_ENST00000380338_length(transcript)=7168nt_BP=876nt
CCTGTTCGCAGCTGCGGCAGTGAGTATGTGTGTGACGGACCCCCGCCGCCCGCGGCTCGGGACCCCTGCCTACCCTCCTTCTTGCCCGCC
GGGCTGTGGAACTAGCGCGTGCCCCCTCGCCGGCCTCGACGTCTCCCGTCCGCCCCTCACTCGTGGCAGGGCGCAGCTCCTGGAGAATCT
GAGCATGGGGAATAAAGTCAGGAAGGATCGCAAGTGAGGATTATATTAATATGATAATTAGCACGCTTCAAGGTTACTGACTTTTTATGA
TGTTTGGTGGCTATGAGACTATAGAAGCATACGAAGATGATCTTTATCGAGATGAGTCATCTAGTGAACTGAGTGTTGATAGTGAGGTGG
AATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGAAGAAAAGAACTCTGGGAATT
CGGAATCTTCGAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCTGTCAGATGGGTCAGAGGTCA
TCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAGCACAAGAAAATGCCCATGGTCTTTCTTCTT
CTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAGATCAGGTGTAATCCGAGAGG
TCATGATTATAGAGGTCAGTTCAAGTGAAGAGGAAGAGAGCACCATTTCAGAAGGTGATAATGTGGAAAGCTGGATGCTACTGGGATGTG
AAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGTGTGCAAAGATCCACCTTACAAAG
TAGAAGAATCTGGGTATGCTGGTTTCATTTTGCCAATTGAAGTTTATTTTAAAAACAAGGAAGAACCTAGGAAAGTCCGCTTTGATTATG
ACTTATTCCTGCATCTTGAAGGCCATCCACCAGTGAATCACCTCCGCTGTGAAAAGCTAACTTTCAACAACCCCACAGAGGACTTTAGGA
GAAAGTTGCTGAAGGCAGGAGGGGACCCTAATAGGAGTATTCATACCAGCAGCAGCAGCAGCAGCAGCAGTAGCAGCAGCAGCAGCAGCA
GCAGCAGCAGCAGTAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGTAGCAGCAGCAGTAGCAGCAGCAGCAGCAGCAGTAGTACCAGTT
TTTCAAAGCCTCACAAATTAATGAAGGAGCACAAGGAAAAACCTTCTAAAGACTCCAGAGAACATAAAAGTGCCTTCAAAGAACCTTCCA
GGGATCACAACAAATCTTCCAAAGAATCCTCTAAGAAACCCAAAGAAAATAAACCACTGAAAGAAGAGAAAATAGTTCCTAAGATGGCCT
TCAAGGAACCTAAACCCATGTCAAAAGAGCCAAAACCAGATAGTAACTTACTCACCATCACCAGTGGACAAGATAAGAAGGCTCCTAGTA
AAAGGCCGCCCATTTCAGATTCTGAAGAACTCTCAGCCAAAAAAAGGAAAAAGAGTAGCTCAGAGGCTTTATTTAAAAGTTTTTCTAGCG
CACCACCACTGATACTCACTTGTTCTGCTGACAAAAAACAGATAAAAGATAAATCTCATGTCAAGATGGGAAAGGTCAAAATTGAAAGTG
AGACATCAGAGAAGAAGAAATCAACGTTACCGCCATTTGATGATATTGTGGATCCCAATGATTCAGATGTGGAGGAGAATATATCCTCTA
AATCTGATTCTGAACAACCCAGTCCTGCCAGCTCCAGCTCCAGCTCCAGCTCCAGCTTCACACCATCCCAGACCAGGCAACAAGGTCCTT
TGAGGTCTATAATGAAAGATCTGCATTCTGATGACAATGAGGAGGAATCAGATGAAGTGGAGGATAACGACAATGACTCTGAAATGGAGA
GGCCTGTAAATAGAGGAGGCAGCCGAAGTCGCAGAGTTAGCTTAAGTGATGGCAGCGATAGTGAAAGCAGTTCTGCTTCTTCACCCCTAC
ATCACGAACCTCCACCACCCTTACTAAAAACCAACAACAACCAGATTCTTGAAGTGAAAAGTCCAATAAAGCAAAGCAAATCAGATAAGC
AAATAAAGAATGGTGAATGTGACAAGGCATACCTAGATGAACTGGTAGAGCTTCACAGAAGGTTAATGACATTGAGAGAAAGACACATTC
TGCAGCAGATCGTGAACCTTATAGAAGAAACTGGACACTTTCATATCACAAACACAACATTTGATTTTGATCTTTGCTCGCTGGACAAAA
CCACAGTCCGTAAACTACAGAGTTACCTGGAAACATCTGGAACATCCTGAGGATATAACAACTGGATGCATCAAGAACTATTGTGTTTTT
TTTTTTTGGTTTTTTTTTTTTTTGGTTGTGATTTTTTGTTCTTGTTGTTTATATGAAAACACTCAAAATGATGCAACCAAAAGGGAAAAA
ATAAAAATCAAACAACCTTCAGCTTTATTTTTCTTTAAAGCCAGTCATCATCTCTTGATAAAGGAGAGGTTAAAGCAAACCAGCCTCAGC
GGACCACTCTTCTCTCCAAGGAAATCCCCGGGAAGAGTTAGCCTGGATAGCCTTGAAAACAAACAAATCAAACACAACACAAGAAAACTC
AAAGAATGTGTATGGTATCATGTATCTCTCTGTGGTGGTTCATTCCACAGGACGAATGCATATTCAACACACTGCCTTATTACATAACTG
ATCTATTTATTATCGCATACAGATATTCTAAGTCGTTGAGGGAATGACACCATCAGACATTATAAGTACTTGGTCCCGTGGATGCTCTTT
CAATGCAGCACCCTTGCCATCCCAAGCCCAGTGACCTTACTCGTATACCGTGCCACTTTCCACCAACTTTTTCCAAGTCCTTTAACTCGT
TGCAGTCTGTATTTTCCACCTTTTGTTTTTCCAGTTCCAGGACACAGATTATCAACTGGGGGGACCAAATAGCCACCTTGATTTTCTTCT
TTGTGGTCTTTTTCCTGAAAGTTGGGGCCCAGTCCTTGGCTGTATCCATGTAATGATCTTGGACCATGGTAGAAAATGCACCAAATAGGA
TCATATGAATTGCTGTCTAGCCTTAGTCAATAAACTTGTAGGACTTTTAAACAAAAGTGTACCTGTAAATGTCCTGAATCCAGCATTGTT
GAGCTGTCATCAACATTCTTGTGTCTGTTTTACTGTTACAATATTAGGTGAATATGGAAGTAAAGGCATTCCACAGGATCATCATTTAAA
AAAAAAGAATTCTGGTCCTGTTTTCTAAAAAAAAAAACTGTTGTAGAAATTCTTAATTTGGATCTATTTATTAGTCAGAGTTTCAGCTTT
CTTCAGCTGCCAGTGTGTTACTCATCTTTATCCTAAAAATCTGGAATCAGAGATTTTTGTTTGTTCACATATGATTCTCTTAGACACTTT
TATATTTGAAAAAATTAAAATCTTTCTTTGGGGAAAAATTCTTGGTTATTCTGCCATAACAGATTATGTATTAACTTGTAGATTCAGTGG
TTCAATACCTGTTTAGTTGCTTGCTAATATTTCCAGAAGGATTTCTTGTATTGGTGAAAGACGGTTGGGGATGGGGGGATTTTTTTGTTC
TTGTTGTACCCTTGTTTTGAAACTAGAAATCTGTCCTGTGGCATGCAAAAGAAAGCAAATTATTTTTAAAAGAAAAAAACCAAAGTACTT
TTGGTGTCATTATTCCATCTTCTCCATAAGTGGAGAAATGAAAAGTAAGAACAGCTCATCTTCAAAGTTTTTACTAGAAATTCAGCCGAA
AAGAAGAGAAATGAAGAAATACTTCTGGATCCAAAGGTTCGTCACTGGATCAGCCTTAAGAAAGTCTCTATGTGTGCTAATAGACCAGTA
TCTCCCTTGTTTGTTCCCATGCCAGATGCTGTCTTTTCATACAGAGATTAACTAGTGTCTGTACAGAAAATGGTCTTTCCAGACCCATTC
TTTTGGGCAGTTATATAAATGCAGATTGATAATGGAGTTATTTCTGCATTTTAAAAAGGGGATTTTTTACACTGTTTCTTTCTATCCAAA
GAAACTATTTTTCCTTTAAAAAATTATAATACAGCCATGCTCCTTGTAAATTATTTCTCTGAAGCGTCCTCCCAGAGGACAAGTGTACTT
TCTCAATAATGTTATGATTCTTAATGACGATTGGCATGAACCGTACTTGAAGCATTTGTTGTATTGTCCACTTCTTGATGTGCAGAGAAA
CTTTGAGTCATTTTGGACATTAGGTGATTGATGAATTGTGTGGTTTCAGTTGCGTTTTGTTTTTAACTTTATAGCTGGAAGGGGAGGGTA
ATGTTTATATGGAAATGTTGCAAATTTTTAAAATATTTTAAAATTTCTAACTGCTAACACATATTCTGATCAAGCCAGAAGTTTATGTGA
TTTAATATATCTGTGTAGTTTAACTAGAAACGTATATATGTAGTTTGGGCCATTTTTATTTCTGTAACTAAATTGTGGGGCAAAAAATAT
GATTTGCCAATGTAAAAATTTTTTCCTTTAAGTTACTAACCAAGAAGCTAGGTAAGATAAGAAATGACCAAACAAAAATAATGATAAGAA
GGACAGCTATTATATGATAAACTTTAGACTTGAAAATTAGGTAATAAAGTTAATTTCTTCAGAATATCCTAAAATGTAAGTTTGTAAATT
GATAAAGTTCAGAAAAACTTATCCATCTTCTACTCATCAAGATAGCAAAGTAAGTTTTTCACAAAATTAAGACTGAGAGTTACGTTATTT
TTTTTGAAGTGGTAATCTTGCTCTCATCTAATTTTTAAATACAGAAATAAAAAGATCCCTTTGAATTAATTTCAAGTAGTTTTAATACCT
CTCTTAAAGTAACCCCTTCAGTTCTGTCACATTTATATACACCCAACTTTGAAGCCTATTAAGAATATCTTTGACATGTGAGTACCCTAA
CAGTGGCTCTGGTTTCTTAAGCACAAAGGGAAAATGGCAGGGTTTAATTTCTTTGGTGTACATATATAAATAGATGTTTCAAATAAAATT
AATTGGGTAAATGTGAATATGGTTTGAACCAGCCAGAGTATGATAAACTTTTAAAAAATTTTTCCTCAGTGATCAGCCAGGGGAAAAAAT
ATATGTACAGAGCTCCTGCCCCTCTGCCCCCTTATAACTTAGCTTTTGCCTCTGGTTTTGCAGCAGGATGTGTGTTGGTGGGTTTGGGGT
TCCTTCTGTCTTCGGATGTAACAGTCATGTTAGCAACAATATTTTGCAGTTACTTCACCATCCTCAGCATAATCTGCCTCTCTCTCAATC
TTAATACAGACAAATAGGTATGTCTATAAATGCGTTCATATAGTGTCAAGGTAGGGAAGACTATAAAAACTTCAGATCAGGAAAAAAATA
TCTCTTAAGAGAGTGTCTTAAACATTTTAAATTGCTAGGCAATTTAAATCTCTCTAATCTGAATATTCACCTTTTGGTGGAAAGAGCCAG
TAATATTGGTTTTCTTCCACTAAAAAGTTTCTTCAAAATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGCCGATATCTTTTACAGGCCC
ACCTAATCTTTAAAAAAAAGAGAAGAAACAATTTTAGGCCTGTATAACATCCTATTTACTACTTCAAGCTCCACAAATGTAGTTAATATA
TTTGTTTAAGAGAGACTTTACTCTTAAATGTTTTAACTTTGCCTACTTAATGGAGTTGGATGTCCAGTGTTGGAAACAGTCAGTGTCTGT
TTGGTGGCTCGTGTTTATTTTTGTCACTGTAGAAGTGATCTGCTCTGGAGTAATTTGCTGTATGCTTATTACTTTCCACCTTTAGCGTTT
TGTGTACTAATGCTATGTACTGCTCCTATATTTATATATACATATATATATATATATACACATATATATTATCAGAGTAATCTTGCTTTG
GACTGTTGCTCTAAAACTATGAATATGATGTAGAGACTACTACAGCTGCAGTGAATGTTAAGGAGTCAATTCCCATGGTTTAGTTTAGTC
TCGGGCTGGAAGTCTACATCTTTTGACCTCTTTTGTTTTATATGATGCTTTTTATTATGTAGGCACTGCCATCCCTGAATATTCCTTGTA
AAGATGCAGTGAAGAAGTCAATTTAAAAGGAAGACAAAGCCACCGCTGTCTGTAAACTGTAAATGTGTATTTTGGCACTTGTACTCCAGT
ATTCTGAAAATAGAGTTATGATGGAAATGCTGACAGATCCTTAATGGTGGCCAGAGCTACCATGCAGTGCAAAAATAAATTAAGTGAAAA
TGTATTATTGAGATTAACAGTGCAAGGCCAATACATTTTATAAATCTGTCAGTATCTTTTTAATGGACTGTGTATGTGTAGTTATGTTGA
AAGATACATTGTGTATGTGTACATGCTTTTGTGTGAATTCAAGGCACACTGTAAGATGTATTTCCCTTCTCTAAAATCCATGTTGAAATG
TAAGTACAGATTGATAGAAATAGGTGTTTTACTTAAACTCATATAATCTGTTTCAGCACCTTTTTTAAAATGTATAATTGTACTGATTTG
CTGAGAGTCATTTGACCAAAGTTTGGCTTTATTTTGCATACAGGAAAAATTAGCCCCTAGCCTTTTCTCAAGAAGTGATGCTGTTTCTAA
AGAAGAATAGATGGGGAGATCTGAGACATCCAGAGAGAGGACAATGTGTCCAAAACCAGCTGAAGGCAGAGAGTCCATGCCTCATTCATT
TTAGGAGTCCCTCATGTCTAACACCATCTTCTGTGTCCTAAAGCCAGTATATATATAATATTTTTAAAACTCTGCAAAGATTGGAACAAG
AAGTGGTGGGATACATTTTTTGGCATAAACTGGGCTATGTGTGCCCGGTATTTTTTCTTTCCCCCCTATTTCTTTGGAGGGTTTTGTTCA
GAAACAATGTGCTATAGCCAGAGAGAGTCGATCTTACAAAGTCCCTGCATTTACTTTCACAGCAAGAACTGCTACCTTGATTAGACAGGA

>100703_100703_1_ZCCHC7-MLLT3_ZCCHC7_chr9_37126939_ENST00000322831_MLLT3_chr9_20456784_ENST00000380338_length(amino acids)=707AA_BP=198
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSE
VITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLG
CEVDDKDDDILLNLVGCENSVTEVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDF
RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEP
SRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFS
SAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQG
PLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSD

--------------------------------------------------------------
>100703_100703_2_ZCCHC7-MLLT3_ZCCHC7_chr9_37126939_ENST00000336755_MLLT3_chr9_20456784_ENST00000380338_length(transcript)=7008nt_BP=716nt
CTCCTTACCTCATTTGTCCTCGCCCCTCCCCGTCCCTCTACGCGTTTTGGTTCCCGGTTGGTGCTTCCTGTTCGCAGCTGCGGCACTTCA
AGGTTACTGACTTTTTATGATGTTTGGTGGCTATGAGACTATAGAAGCATACGAAGATGATCTTTATCGAGATGAGTCATCTAGTGAACT
GAGTGTTGATAGTGAGGTGGAATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGA
AGAAAAGAACTCTGGGAATTCGGAATCTTCGAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCT
GTCAGATGGGTCAGAGGTCATCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAGCACAAGAAAA
TGCCCATGGTCTTTCTTCTTCTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAG
ATCAGGTGTAATCCGAGAGGTCATGATTATAGAGGTCAGTTCAAGTGAAGAGGAAGAGAGCACCATTTCAGAAGGTGATAATGTGGAAAG
CTGGATGCTACTGGGATGTGAAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGTGTG
CAAAGATCCACCTTACAAAGTAGAAGAATCTGGGTATGCTGGTTTCATTTTGCCAATTGAAGTTTATTTTAAAAACAAGGAAGAACCTAG
GAAAGTCCGCTTTGATTATGACTTATTCCTGCATCTTGAAGGCCATCCACCAGTGAATCACCTCCGCTGTGAAAAGCTAACTTTCAACAA
CCCCACAGAGGACTTTAGGAGAAAGTTGCTGAAGGCAGGAGGGGACCCTAATAGGAGTATTCATACCAGCAGCAGCAGCAGCAGCAGCAG
TAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGTAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGTAGCAGCAGCAGTAGCAGCAGCAG
CAGCAGCAGTAGTACCAGTTTTTCAAAGCCTCACAAATTAATGAAGGAGCACAAGGAAAAACCTTCTAAAGACTCCAGAGAACATAAAAG
TGCCTTCAAAGAACCTTCCAGGGATCACAACAAATCTTCCAAAGAATCCTCTAAGAAACCCAAAGAAAATAAACCACTGAAAGAAGAGAA
AATAGTTCCTAAGATGGCCTTCAAGGAACCTAAACCCATGTCAAAAGAGCCAAAACCAGATAGTAACTTACTCACCATCACCAGTGGACA
AGATAAGAAGGCTCCTAGTAAAAGGCCGCCCATTTCAGATTCTGAAGAACTCTCAGCCAAAAAAAGGAAAAAGAGTAGCTCAGAGGCTTT
ATTTAAAAGTTTTTCTAGCGCACCACCACTGATACTCACTTGTTCTGCTGACAAAAAACAGATAAAAGATAAATCTCATGTCAAGATGGG
AAAGGTCAAAATTGAAAGTGAGACATCAGAGAAGAAGAAATCAACGTTACCGCCATTTGATGATATTGTGGATCCCAATGATTCAGATGT
GGAGGAGAATATATCCTCTAAATCTGATTCTGAACAACCCAGTCCTGCCAGCTCCAGCTCCAGCTCCAGCTCCAGCTTCACACCATCCCA
GACCAGGCAACAAGGTCCTTTGAGGTCTATAATGAAAGATCTGCATTCTGATGACAATGAGGAGGAATCAGATGAAGTGGAGGATAACGA
CAATGACTCTGAAATGGAGAGGCCTGTAAATAGAGGAGGCAGCCGAAGTCGCAGAGTTAGCTTAAGTGATGGCAGCGATAGTGAAAGCAG
TTCTGCTTCTTCACCCCTACATCACGAACCTCCACCACCCTTACTAAAAACCAACAACAACCAGATTCTTGAAGTGAAAAGTCCAATAAA
GCAAAGCAAATCAGATAAGCAAATAAAGAATGGTGAATGTGACAAGGCATACCTAGATGAACTGGTAGAGCTTCACAGAAGGTTAATGAC
ATTGAGAGAAAGACACATTCTGCAGCAGATCGTGAACCTTATAGAAGAAACTGGACACTTTCATATCACAAACACAACATTTGATTTTGA
TCTTTGCTCGCTGGACAAAACCACAGTCCGTAAACTACAGAGTTACCTGGAAACATCTGGAACATCCTGAGGATATAACAACTGGATGCA
TCAAGAACTATTGTGTTTTTTTTTTTTGGTTTTTTTTTTTTTTGGTTGTGATTTTTTGTTCTTGTTGTTTATATGAAAACACTCAAAATG
ATGCAACCAAAAGGGAAAAAATAAAAATCAAACAACCTTCAGCTTTATTTTTCTTTAAAGCCAGTCATCATCTCTTGATAAAGGAGAGGT
TAAAGCAAACCAGCCTCAGCGGACCACTCTTCTCTCCAAGGAAATCCCCGGGAAGAGTTAGCCTGGATAGCCTTGAAAACAAACAAATCA
AACACAACACAAGAAAACTCAAAGAATGTGTATGGTATCATGTATCTCTCTGTGGTGGTTCATTCCACAGGACGAATGCATATTCAACAC
ACTGCCTTATTACATAACTGATCTATTTATTATCGCATACAGATATTCTAAGTCGTTGAGGGAATGACACCATCAGACATTATAAGTACT
TGGTCCCGTGGATGCTCTTTCAATGCAGCACCCTTGCCATCCCAAGCCCAGTGACCTTACTCGTATACCGTGCCACTTTCCACCAACTTT
TTCCAAGTCCTTTAACTCGTTGCAGTCTGTATTTTCCACCTTTTGTTTTTCCAGTTCCAGGACACAGATTATCAACTGGGGGGACCAAAT
AGCCACCTTGATTTTCTTCTTTGTGGTCTTTTTCCTGAAAGTTGGGGCCCAGTCCTTGGCTGTATCCATGTAATGATCTTGGACCATGGT
AGAAAATGCACCAAATAGGATCATATGAATTGCTGTCTAGCCTTAGTCAATAAACTTGTAGGACTTTTAAACAAAAGTGTACCTGTAAAT
GTCCTGAATCCAGCATTGTTGAGCTGTCATCAACATTCTTGTGTCTGTTTTACTGTTACAATATTAGGTGAATATGGAAGTAAAGGCATT
CCACAGGATCATCATTTAAAAAAAAAGAATTCTGGTCCTGTTTTCTAAAAAAAAAAACTGTTGTAGAAATTCTTAATTTGGATCTATTTA
TTAGTCAGAGTTTCAGCTTTCTTCAGCTGCCAGTGTGTTACTCATCTTTATCCTAAAAATCTGGAATCAGAGATTTTTGTTTGTTCACAT
ATGATTCTCTTAGACACTTTTATATTTGAAAAAATTAAAATCTTTCTTTGGGGAAAAATTCTTGGTTATTCTGCCATAACAGATTATGTA
TTAACTTGTAGATTCAGTGGTTCAATACCTGTTTAGTTGCTTGCTAATATTTCCAGAAGGATTTCTTGTATTGGTGAAAGACGGTTGGGG
ATGGGGGGATTTTTTTGTTCTTGTTGTACCCTTGTTTTGAAACTAGAAATCTGTCCTGTGGCATGCAAAAGAAAGCAAATTATTTTTAAA
AGAAAAAAACCAAAGTACTTTTGGTGTCATTATTCCATCTTCTCCATAAGTGGAGAAATGAAAAGTAAGAACAGCTCATCTTCAAAGTTT
TTACTAGAAATTCAGCCGAAAAGAAGAGAAATGAAGAAATACTTCTGGATCCAAAGGTTCGTCACTGGATCAGCCTTAAGAAAGTCTCTA
TGTGTGCTAATAGACCAGTATCTCCCTTGTTTGTTCCCATGCCAGATGCTGTCTTTTCATACAGAGATTAACTAGTGTCTGTACAGAAAA
TGGTCTTTCCAGACCCATTCTTTTGGGCAGTTATATAAATGCAGATTGATAATGGAGTTATTTCTGCATTTTAAAAAGGGGATTTTTTAC
ACTGTTTCTTTCTATCCAAAGAAACTATTTTTCCTTTAAAAAATTATAATACAGCCATGCTCCTTGTAAATTATTTCTCTGAAGCGTCCT
CCCAGAGGACAAGTGTACTTTCTCAATAATGTTATGATTCTTAATGACGATTGGCATGAACCGTACTTGAAGCATTTGTTGTATTGTCCA
CTTCTTGATGTGCAGAGAAACTTTGAGTCATTTTGGACATTAGGTGATTGATGAATTGTGTGGTTTCAGTTGCGTTTTGTTTTTAACTTT
ATAGCTGGAAGGGGAGGGTAATGTTTATATGGAAATGTTGCAAATTTTTAAAATATTTTAAAATTTCTAACTGCTAACACATATTCTGAT
CAAGCCAGAAGTTTATGTGATTTAATATATCTGTGTAGTTTAACTAGAAACGTATATATGTAGTTTGGGCCATTTTTATTTCTGTAACTA
AATTGTGGGGCAAAAAATATGATTTGCCAATGTAAAAATTTTTTCCTTTAAGTTACTAACCAAGAAGCTAGGTAAGATAAGAAATGACCA
AACAAAAATAATGATAAGAAGGACAGCTATTATATGATAAACTTTAGACTTGAAAATTAGGTAATAAAGTTAATTTCTTCAGAATATCCT
AAAATGTAAGTTTGTAAATTGATAAAGTTCAGAAAAACTTATCCATCTTCTACTCATCAAGATAGCAAAGTAAGTTTTTCACAAAATTAA
GACTGAGAGTTACGTTATTTTTTTTGAAGTGGTAATCTTGCTCTCATCTAATTTTTAAATACAGAAATAAAAAGATCCCTTTGAATTAAT
TTCAAGTAGTTTTAATACCTCTCTTAAAGTAACCCCTTCAGTTCTGTCACATTTATATACACCCAACTTTGAAGCCTATTAAGAATATCT
TTGACATGTGAGTACCCTAACAGTGGCTCTGGTTTCTTAAGCACAAAGGGAAAATGGCAGGGTTTAATTTCTTTGGTGTACATATATAAA
TAGATGTTTCAAATAAAATTAATTGGGTAAATGTGAATATGGTTTGAACCAGCCAGAGTATGATAAACTTTTAAAAAATTTTTCCTCAGT
GATCAGCCAGGGGAAAAAATATATGTACAGAGCTCCTGCCCCTCTGCCCCCTTATAACTTAGCTTTTGCCTCTGGTTTTGCAGCAGGATG
TGTGTTGGTGGGTTTGGGGTTCCTTCTGTCTTCGGATGTAACAGTCATGTTAGCAACAATATTTTGCAGTTACTTCACCATCCTCAGCAT
AATCTGCCTCTCTCTCAATCTTAATACAGACAAATAGGTATGTCTATAAATGCGTTCATATAGTGTCAAGGTAGGGAAGACTATAAAAAC
TTCAGATCAGGAAAAAAATATCTCTTAAGAGAGTGTCTTAAACATTTTAAATTGCTAGGCAATTTAAATCTCTCTAATCTGAATATTCAC
CTTTTGGTGGAAAGAGCCAGTAATATTGGTTTTCTTCCACTAAAAAGTTTCTTCAAAATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTG
CCGATATCTTTTACAGGCCCACCTAATCTTTAAAAAAAAGAGAAGAAACAATTTTAGGCCTGTATAACATCCTATTTACTACTTCAAGCT
CCACAAATGTAGTTAATATATTTGTTTAAGAGAGACTTTACTCTTAAATGTTTTAACTTTGCCTACTTAATGGAGTTGGATGTCCAGTGT
TGGAAACAGTCAGTGTCTGTTTGGTGGCTCGTGTTTATTTTTGTCACTGTAGAAGTGATCTGCTCTGGAGTAATTTGCTGTATGCTTATT
ACTTTCCACCTTTAGCGTTTTGTGTACTAATGCTATGTACTGCTCCTATATTTATATATACATATATATATATATATACACATATATATT
ATCAGAGTAATCTTGCTTTGGACTGTTGCTCTAAAACTATGAATATGATGTAGAGACTACTACAGCTGCAGTGAATGTTAAGGAGTCAAT
TCCCATGGTTTAGTTTAGTCTCGGGCTGGAAGTCTACATCTTTTGACCTCTTTTGTTTTATATGATGCTTTTTATTATGTAGGCACTGCC
ATCCCTGAATATTCCTTGTAAAGATGCAGTGAAGAAGTCAATTTAAAAGGAAGACAAAGCCACCGCTGTCTGTAAACTGTAAATGTGTAT
TTTGGCACTTGTACTCCAGTATTCTGAAAATAGAGTTATGATGGAAATGCTGACAGATCCTTAATGGTGGCCAGAGCTACCATGCAGTGC
AAAAATAAATTAAGTGAAAATGTATTATTGAGATTAACAGTGCAAGGCCAATACATTTTATAAATCTGTCAGTATCTTTTTAATGGACTG
TGTATGTGTAGTTATGTTGAAAGATACATTGTGTATGTGTACATGCTTTTGTGTGAATTCAAGGCACACTGTAAGATGTATTTCCCTTCT
CTAAAATCCATGTTGAAATGTAAGTACAGATTGATAGAAATAGGTGTTTTACTTAAACTCATATAATCTGTTTCAGCACCTTTTTTAAAA
TGTATAATTGTACTGATTTGCTGAGAGTCATTTGACCAAAGTTTGGCTTTATTTTGCATACAGGAAAAATTAGCCCCTAGCCTTTTCTCA
AGAAGTGATGCTGTTTCTAAAGAAGAATAGATGGGGAGATCTGAGACATCCAGAGAGAGGACAATGTGTCCAAAACCAGCTGAAGGCAGA
GAGTCCATGCCTCATTCATTTTAGGAGTCCCTCATGTCTAACACCATCTTCTGTGTCCTAAAGCCAGTATATATATAATATTTTTAAAAC
TCTGCAAAGATTGGAACAAGAAGTGGTGGGATACATTTTTTGGCATAAACTGGGCTATGTGTGCCCGGTATTTTTTCTTTCCCCCCTATT
TCTTTGGAGGGTTTTGTTCAGAAACAATGTGCTATAGCCAGAGAGAGTCGATCTTACAAAGTCCCTGCATTTACTTTCACAGCAAGAACT

>100703_100703_2_ZCCHC7-MLLT3_ZCCHC7_chr9_37126939_ENST00000336755_MLLT3_chr9_20456784_ENST00000380338_length(amino acids)=707AA_BP=198
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSE
VITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLG
CEVDDKDDDILLNLVGCENSVTEVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDF
RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEP
SRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFS
SAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQG
PLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZCCHC7-MLLT3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZCCHC7-MLLT3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZCCHC7-MLLT3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource