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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZCCHC7-TEK (FusionGDB2 ID:100712)

Fusion Gene Summary for ZCCHC7-TEK

check button Fusion gene summary
Fusion gene informationFusion gene name: ZCCHC7-TEK
Fusion gene ID: 100712
HgeneTgene
Gene symbol

ZCCHC7

TEK

Gene ID

84186

7010

Gene namezinc finger CCHC-type containing 7TEK receptor tyrosine kinase
SynonymsAIR1|HSPC086CD202B|GLC3E|TIE-2|TIE2|VMCM|VMCM1
Cytomap

9p13.2

9p21.2

Type of geneprotein-codingprotein-coding
Descriptionzinc finger CCHC domain-containing protein 7TRAMP-like complex RNA-binding factor ZCCHC7zinc finger, CCHC domain containing 7angiopoietin-1 receptorTEK tyrosine kinase, endothelialendothelial tyrosine kinasetunica interna endothelial cell kinasetyrosine kinase with Ig and EGF homology domains-2tyrosine-protein kinase receptor TEKtyrosine-protein kinase receptor TIE-2
Modification date2020032020200322
UniProtAcc.

TEKT5

Ensembl transtripts involved in fusion geneENST00000461038, ENST00000322831, 
ENST00000336755, ENST00000534928, 
ENST00000380036, ENST00000406359, 
ENST00000519097, 
Fusion gene scores* DoF score29 X 11 X 11=35095 X 5 X 2=50
# samples 295
** MAII scorelog2(29/3509*10)=-3.59693514238723
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/50*10)=0
Context

PubMed: ZCCHC7 [Title/Abstract] AND TEK [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZCCHC7(37126939)-TEK(27197313), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTEK

GO:0001934

positive regulation of protein phosphorylation

15284220

TgeneTEK

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

15284220

TgeneTEK

GO:0010595

positive regulation of endothelial cell migration

15284220

TgeneTEK

GO:0018108

peptidyl-tyrosine phosphorylation

11513602

TgeneTEK

GO:0045766

positive regulation of angiogenesis

15284220

TgeneTEK

GO:0046777

protein autophosphorylation

11513602

TgeneTEK

GO:0048014

Tie signaling pathway

15284220|19223473

TgeneTEK

GO:0051897

positive regulation of protein kinase B signaling

19615361

TgeneTEK

GO:0070374

positive regulation of ERK1 and ERK2 cascade

19615361


check buttonFusion gene breakpoints across ZCCHC7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TEK (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-XF-A9T4-01AZCCHC7chr9

37126939

-TEKchr9

27197313

+
ChimerDB4BLCATCGA-XF-A9T4-01AZCCHC7chr9

37126939

+TEKchr9

27197313

+
ChimerDB4BLCATCGA-XF-A9T4ZCCHC7chr9

37126939

+TEKchr9

27197313

+


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Fusion Gene ORF analysis for ZCCHC7-TEK

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000461038ENST00000380036ZCCHC7chr9

37126939

+TEKchr9

27197313

+
3UTR-3CDSENST00000461038ENST00000406359ZCCHC7chr9

37126939

+TEKchr9

27197313

+
3UTR-3CDSENST00000461038ENST00000519097ZCCHC7chr9

37126939

+TEKchr9

27197313

+
In-frameENST00000322831ENST00000380036ZCCHC7chr9

37126939

+TEKchr9

27197313

+
In-frameENST00000322831ENST00000406359ZCCHC7chr9

37126939

+TEKchr9

27197313

+
In-frameENST00000322831ENST00000519097ZCCHC7chr9

37126939

+TEKchr9

27197313

+
In-frameENST00000336755ENST00000380036ZCCHC7chr9

37126939

+TEKchr9

27197313

+
In-frameENST00000336755ENST00000406359ZCCHC7chr9

37126939

+TEKchr9

27197313

+
In-frameENST00000336755ENST00000519097ZCCHC7chr9

37126939

+TEKchr9

27197313

+
intron-3CDSENST00000534928ENST00000380036ZCCHC7chr9

37126939

+TEKchr9

27197313

+
intron-3CDSENST00000534928ENST00000406359ZCCHC7chr9

37126939

+TEKchr9

27197313

+
intron-3CDSENST00000534928ENST00000519097ZCCHC7chr9

37126939

+TEKchr9

27197313

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000336755ZCCHC7chr937126939+ENST00000519097TEKchr927197313+29197161062463785
ENST00000336755ZCCHC7chr937126939+ENST00000380036TEKchr927197313+34107161062466786
ENST00000336755ZCCHC7chr937126939+ENST00000406359TEKchr927197313+29817161062466786
ENST00000322831ZCCHC7chr937126939+ENST00000519097TEKchr927197313+30798762662623785
ENST00000322831ZCCHC7chr937126939+ENST00000380036TEKchr927197313+35708762662626786
ENST00000322831ZCCHC7chr937126939+ENST00000406359TEKchr927197313+31418762662626786

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000336755ENST00000519097ZCCHC7chr937126939+TEKchr927197313+0.0006365190.9993635
ENST00000336755ENST00000380036ZCCHC7chr937126939+TEKchr927197313+0.0003404020.99965966
ENST00000336755ENST00000406359ZCCHC7chr937126939+TEKchr927197313+0.0005113820.9994886
ENST00000322831ENST00000519097ZCCHC7chr937126939+TEKchr927197313+0.0008109840.99918896
ENST00000322831ENST00000380036ZCCHC7chr937126939+TEKchr927197313+0.0003962150.9996038
ENST00000322831ENST00000406359ZCCHC7chr937126939+TEKchr927197313+0.0006446910.99935526

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Fusion Genomic Features for ZCCHC7-TEK


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZCCHC7chr937126939+TEKchr927197312+2.61E-050.9999739
ZCCHC7chr937126939+TEKchr927197312+2.61E-050.9999739
ZCCHC7chr937126939+TEKchr927197312+2.61E-050.9999739
ZCCHC7chr937126939+TEKchr927197312+2.61E-050.9999739

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZCCHC7-TEK


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:37126939/chr9:27197313)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.TEK

TEKT5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.485

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTEKchr9:37126939chr9:27197313ENST000003800361023545_6365411125.0DomainFibronectin type-III 2
TgeneTEKchr9:37126939chr9:27197313ENST000003800361023641_7355411125.0DomainFibronectin type-III 3
TgeneTEKchr9:37126939chr9:27197313ENST000003800361023824_10965411125.0DomainProtein kinase
TgeneTEKchr9:37126939chr9:27197313ENST00000406359922545_6364981082.0DomainFibronectin type-III 2
TgeneTEKchr9:37126939chr9:27197313ENST00000406359922641_7354981082.0DomainFibronectin type-III 3
TgeneTEKchr9:37126939chr9:27197313ENST00000406359922824_10964981082.0DomainProtein kinase
TgeneTEKchr9:37126939chr9:27197313ENST00000519097821447_541394977.0DomainFibronectin type-III 1
TgeneTEKchr9:37126939chr9:27197313ENST00000519097821545_636394977.0DomainFibronectin type-III 2
TgeneTEKchr9:37126939chr9:27197313ENST00000519097821641_735394977.0DomainFibronectin type-III 3
TgeneTEKchr9:37126939chr9:27197313ENST00000519097821824_1096394977.0DomainProtein kinase
TgeneTEKchr9:37126939chr9:27197313ENST000003800361023830_8385411125.0Nucleotide bindingATP
TgeneTEKchr9:37126939chr9:27197313ENST00000406359922830_8384981082.0Nucleotide bindingATP
TgeneTEKchr9:37126939chr9:27197313ENST00000519097821830_838394977.0Nucleotide bindingATP
TgeneTEKchr9:37126939chr9:27197313ENST000003800361023770_11245411125.0Topological domainCytoplasmic
TgeneTEKchr9:37126939chr9:27197313ENST00000406359922770_11244981082.0Topological domainCytoplasmic
TgeneTEKchr9:37126939chr9:27197313ENST00000519097821770_1124394977.0Topological domainCytoplasmic
TgeneTEKchr9:37126939chr9:27197313ENST000003800361023749_7695411125.0TransmembraneHelical
TgeneTEKchr9:37126939chr9:27197313ENST00000406359922749_7694981082.0TransmembraneHelical
TgeneTEKchr9:37126939chr9:27197313ENST00000519097821749_769394977.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZCCHC7chr9:37126939chr9:27197313ENST00000336755+29241_258203544.0Zinc fingerCCHC-type 1
HgeneZCCHC7chr9:37126939chr9:27197313ENST00000336755+29263_280203544.0Zinc fingerCCHC-type 2
HgeneZCCHC7chr9:37126939chr9:27197313ENST00000336755+29304_321203544.0Zinc fingerCCHC-type 3
HgeneZCCHC7chr9:37126939chr9:27197313ENST00000336755+29348_365203544.0Zinc fingerCCHC-type 4
TgeneTEKchr9:37126939chr9:27197313ENST000003800361023210_2525411125.0DomainEGF-like 1
TgeneTEKchr9:37126939chr9:27197313ENST000003800361023254_2995411125.0DomainEGF-like 2
TgeneTEKchr9:37126939chr9:27197313ENST000003800361023301_3415411125.0DomainEGF-like 3
TgeneTEKchr9:37126939chr9:27197313ENST000003800361023350_4405411125.0DomainNote=Ig-like C2-type 2
TgeneTEKchr9:37126939chr9:27197313ENST000003800361023447_5415411125.0DomainFibronectin type-III 1
TgeneTEKchr9:37126939chr9:27197313ENST00000380036102344_1235411125.0DomainNote=Ig-like C2-type 1
TgeneTEKchr9:37126939chr9:27197313ENST00000406359922210_2524981082.0DomainEGF-like 1
TgeneTEKchr9:37126939chr9:27197313ENST00000406359922254_2994981082.0DomainEGF-like 2
TgeneTEKchr9:37126939chr9:27197313ENST00000406359922301_3414981082.0DomainEGF-like 3
TgeneTEKchr9:37126939chr9:27197313ENST00000406359922350_4404981082.0DomainNote=Ig-like C2-type 2
TgeneTEKchr9:37126939chr9:27197313ENST00000406359922447_5414981082.0DomainFibronectin type-III 1
TgeneTEKchr9:37126939chr9:27197313ENST0000040635992244_1234981082.0DomainNote=Ig-like C2-type 1
TgeneTEKchr9:37126939chr9:27197313ENST00000519097821210_252394977.0DomainEGF-like 1
TgeneTEKchr9:37126939chr9:27197313ENST00000519097821254_299394977.0DomainEGF-like 2
TgeneTEKchr9:37126939chr9:27197313ENST00000519097821301_341394977.0DomainEGF-like 3
TgeneTEKchr9:37126939chr9:27197313ENST00000519097821350_440394977.0DomainNote=Ig-like C2-type 2
TgeneTEKchr9:37126939chr9:27197313ENST0000051909782144_123394977.0DomainNote=Ig-like C2-type 1
TgeneTEKchr9:37126939chr9:27197313ENST00000380036102323_7485411125.0Topological domainExtracellular
TgeneTEKchr9:37126939chr9:27197313ENST0000040635992223_7484981082.0Topological domainExtracellular
TgeneTEKchr9:37126939chr9:27197313ENST0000051909782123_748394977.0Topological domainExtracellular


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Fusion Gene Sequence for ZCCHC7-TEK


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>100712_100712_1_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000322831_TEK_chr9_27197313_ENST00000380036_length(transcript)=3570nt_BP=876nt
CCTGTTCGCAGCTGCGGCAGTGAGTATGTGTGTGACGGACCCCCGCCGCCCGCGGCTCGGGACCCCTGCCTACCCTCCTTCTTGCCCGCC
GGGCTGTGGAACTAGCGCGTGCCCCCTCGCCGGCCTCGACGTCTCCCGTCCGCCCCTCACTCGTGGCAGGGCGCAGCTCCTGGAGAATCT
GAGCATGGGGAATAAAGTCAGGAAGGATCGCAAGTGAGGATTATATTAATATGATAATTAGCACGCTTCAAGGTTACTGACTTTTTATGA
TGTTTGGTGGCTATGAGACTATAGAAGCATACGAAGATGATCTTTATCGAGATGAGTCATCTAGTGAACTGAGTGTTGATAGTGAGGTGG
AATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGAAGAAAAGAACTCTGGGAATT
CGGAATCTTCGAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCTGTCAGATGGGTCAGAGGTCA
TCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAGCACAAGAAAATGCCCATGGTCTTTCTTCTT
CTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAGATCAGGTGTAATCCGAGAGG
TCATGATTATAGAGGTCAGTTCAAGTGAAGAGGAAGAGAGCACCATTTCAGAAGGTGATAATGTGGAAAGCTGGATGCTACTGGGATGTG
AAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGGACTCCCTCCTCCAAGAGGTCTAA
ATCTCCTGCCTAAAAGTCAGACCACTCTAAATTTGACCTGGCAACCAATATTTCCAAGCTCGGAAGATGACTTTTATGTTGAAGTGGAGA
GAAGGTCTGTGCAAAAAAGTGATCAGCAGAATATTAAAGTTCCAGGCAACTTGACTTCGGTGCTACTTAACAACTTACATCCCAGGGAGC
AGTACGTGGTCCGAGCTAGAGTCAACACCAAGGCCCAGGGGGAATGGAGTGAAGATCTCACTGCTTGGACCCTTAGTGACATTCTTCCTC
CTCAACCAGAAAACATCAAGATTTCCAACATTACACACTCCTCAGCTGTGATTTCTTGGACAATATTGGATGGCTATTCTATTTCTTCTA
TTACTATCCGTTACAAGGTTCAAGGCAAGAATGAAGACCAGCACGTTGATGTGAAGATAAAGAATGCCACCATCACTCAGTATCAGCTCA
AGGGCCTAGAGCCTGAAACAGCATACCAGGTGGACATTTTTGCAGAGAACAACATAGGGTCAAGCAACCCAGCCTTTTCTCATGAACTGG
TGACCCTCCCAGAATCTCAAGCACCAGCGGACCTCGGAGGGGGGAAGATGCTGCTTATAGCCATCCTTGGCTCTGCTGGAATGACCTGCC
TGACTGTGCTGTTGGCCTTTCTGATCATATTGCAATTGAAGAGGGCAAATGTGCAAAGGAGAATGGCCCAAGCCTTCCAAAACGTGAGGG
AAGAACCAGCTGTGCAGTTCAACTCAGGGACTCTGGCCCTAAACAGGAAGGTCAAAAACAACCCAGATCCTACAATTTATCCAGTGCTTG
ACTGGAATGACATCAAATTTCAAGATGTGATTGGGGAGGGCAATTTTGGCCAAGTTCTTAAGGCGCGCATCAAGAAGGATGGGTTACGGA
TGGATGCTGCCATCAAAAGAATGAAAGAATATGCCTCCAAAGATGATCACAGGGACTTTGCAGGAGAACTGGAAGTTCTTTGTAAACTTG
GACACCATCCAAACATCATCAATCTCTTAGGAGCATGTGAACATCGAGGCTACTTGTACCTGGCCATTGAGTACGCGCCCCATGGAAACC
TTCTGGACTTCCTTCGCAAGAGCCGTGTGCTGGAGACGGACCCAGCATTTGCCATTGCCAATAGCACCGCGTCCACACTGTCCTCCCAGC
AGCTCCTTCACTTCGCTGCCGACGTGGCCCGGGGCATGGACTACTTGAGCCAAAAACAGTTTATCCACAGGGATCTGGCTGCCAGAAACA
TTTTAGTTGGTGAAAACTATGTGGCAAAAATAGCAGATTTTGGATTGTCCCGAGGTCAAGAGGTGTATGTGAAAAAGACAATGGGAAGGC
TCCCAGTGCGCTGGATGGCCATCGAGTCACTGAATTACAGTGTGTACACAACCAACAGTGATGTATGGTCCTATGGTGTGTTACTATGGG
AGATTGTTAGCTTAGGAGGCACACCCTACTGCGGGATGACTTGTGCAGAACTCTACGAGAAGCTGCCCCAGGGCTACAGACTGGAGAAGC
CCCTGAACTGTGATGATGAGGTGTATGATCTAATGAGACAATGCTGGCGGGAGAAGCCTTATGAGAGGCCATCATTTGCCCAGATATTGG
TGTCCTTAAACAGAATGTTAGAGGAGCGAAAGACCTACGTGAATACCACGCTTTATGAGAAGTTTACTTATGCAGGAATTGACTGTTCTG
CTGAAGAAGCGGCCTAGGACAGAACATCTGTATACCCTCTGTTTCCCTTTCACTGGCATGGGAGACCCTTGACACCTGCTGAGAAAACAT
GCCTCTGCCAAAGGATGTGATATATAAGTGTACATATGTGCTGTACACCTGGGACCTTCACCACTGTAGATCCCATGCATGGATCTATGT
AGTATGCTCTGACTCTAATAGGACTGTATATACTGTTTTAAGAATGGGCTGAAATCAGAATGCCTGTTTGTGGTTTCATATGCAATAATA
TATTTTTTTAAAAATGTGGACTTCATAGGAAGGCGTGAGTACAATTAGTATAATGCATAACTCATTGTTGTCCTAGATATTTTGATATTT
ACCTTTATGTTGAATGCTATTAAATGTTTTCCTGTGTCAAAGTAAAATATTGTTAATAAACCTAACAATGACCCTGATAGTACAGGTTAA
GTGAGAGAACTATATGAATTCTAACAAGTCATAGGTTAATATTTAAGACACTGAAAAATCTAAGTGATATAAATCAGATTCTTCTCTCTC
AATTTTATCCCTCACCTGTAGCAGCCAGTCCCGTTTCATTTAGTCATGTGACCACTCTGTCTTGTGTTTCCACAGCCTGCAAGTCAGTCC
AGGATGCTAACATCTAAAAATAGACTTAAATCTCATTGCTTACAAGCCTAAGAATCTTTAGAGAAGTATACATAAGTTTAGGATAAAATA
ATGGGATTTTCTTTTCTTTTCTCTGGTAATATTGACTTGTATATTTTAAGAAATAACAGAAAGCCTGGGTGACATTTGGGAGACATGTGA
CATTTATATATTGAATTAATATCCCTACATGTATTGCACATTGTAAAAAGTTTTAGTTTTGATGAGTTGTGAGTTTACCTTGTATACTGT

>100712_100712_1_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000322831_TEK_chr9_27197313_ENST00000380036_length(amino acids)=786AA_BP=203
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSE
VITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLG
CEVDDKDDDILLNLVGCENSVTEGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLHPR
EQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAVISWTILDGYSISSITIRYKVQGKNEDQHVDVKIKNATITQYQ
LKGLEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNV
REEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCK
LGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAAR
NILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLE

--------------------------------------------------------------
>100712_100712_2_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000322831_TEK_chr9_27197313_ENST00000406359_length(transcript)=3141nt_BP=876nt
CCTGTTCGCAGCTGCGGCAGTGAGTATGTGTGTGACGGACCCCCGCCGCCCGCGGCTCGGGACCCCTGCCTACCCTCCTTCTTGCCCGCC
GGGCTGTGGAACTAGCGCGTGCCCCCTCGCCGGCCTCGACGTCTCCCGTCCGCCCCTCACTCGTGGCAGGGCGCAGCTCCTGGAGAATCT
GAGCATGGGGAATAAAGTCAGGAAGGATCGCAAGTGAGGATTATATTAATATGATAATTAGCACGCTTCAAGGTTACTGACTTTTTATGA
TGTTTGGTGGCTATGAGACTATAGAAGCATACGAAGATGATCTTTATCGAGATGAGTCATCTAGTGAACTGAGTGTTGATAGTGAGGTGG
AATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGAAGAAAAGAACTCTGGGAATT
CGGAATCTTCGAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCTGTCAGATGGGTCAGAGGTCA
TCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAGCACAAGAAAATGCCCATGGTCTTTCTTCTT
CTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAGATCAGGTGTAATCCGAGAGG
TCATGATTATAGAGGTCAGTTCAAGTGAAGAGGAAGAGAGCACCATTTCAGAAGGTGATAATGTGGAAAGCTGGATGCTACTGGGATGTG
AAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGGACTCCCTCCTCCAAGAGGTCTAA
ATCTCCTGCCTAAAAGTCAGACCACTCTAAATTTGACCTGGCAACCAATATTTCCAAGCTCGGAAGATGACTTTTATGTTGAAGTGGAGA
GAAGGTCTGTGCAAAAAAGTGATCAGCAGAATATTAAAGTTCCAGGCAACTTGACTTCGGTGCTACTTAACAACTTACATCCCAGGGAGC
AGTACGTGGTCCGAGCTAGAGTCAACACCAAGGCCCAGGGGGAATGGAGTGAAGATCTCACTGCTTGGACCCTTAGTGACATTCTTCCTC
CTCAACCAGAAAACATCAAGATTTCCAACATTACACACTCCTCAGCTGTGATTTCTTGGACAATATTGGATGGCTATTCTATTTCTTCTA
TTACTATCCGTTACAAGGTTCAAGGCAAGAATGAAGACCAGCACGTTGATGTGAAGATAAAGAATGCCACCATCACTCAGTATCAGCTCA
AGGGCCTAGAGCCTGAAACAGCATACCAGGTGGACATTTTTGCAGAGAACAACATAGGGTCAAGCAACCCAGCCTTTTCTCATGAACTGG
TGACCCTCCCAGAATCTCAAGCACCAGCGGACCTCGGAGGGGGGAAGATGCTGCTTATAGCCATCCTTGGCTCTGCTGGAATGACCTGCC
TGACTGTGCTGTTGGCCTTTCTGATCATATTGCAATTGAAGAGGGCAAATGTGCAAAGGAGAATGGCCCAAGCCTTCCAAAACGTGAGGG
AAGAACCAGCTGTGCAGTTCAACTCAGGGACTCTGGCCCTAAACAGGAAGGTCAAAAACAACCCAGATCCTACAATTTATCCAGTGCTTG
ACTGGAATGACATCAAATTTCAAGATGTGATTGGGGAGGGCAATTTTGGCCAAGTTCTTAAGGCGCGCATCAAGAAGGATGGGTTACGGA
TGGATGCTGCCATCAAAAGAATGAAAGAATATGCCTCCAAAGATGATCACAGGGACTTTGCAGGAGAACTGGAAGTTCTTTGTAAACTTG
GACACCATCCAAACATCATCAATCTCTTAGGAGCATGTGAACATCGAGGCTACTTGTACCTGGCCATTGAGTACGCGCCCCATGGAAACC
TTCTGGACTTCCTTCGCAAGAGCCGTGTGCTGGAGACGGACCCAGCATTTGCCATTGCCAATAGCACCGCGTCCACACTGTCCTCCCAGC
AGCTCCTTCACTTCGCTGCCGACGTGGCCCGGGGCATGGACTACTTGAGCCAAAAACAGTTTATCCACAGGGATCTGGCTGCCAGAAACA
TTTTAGTTGGTGAAAACTATGTGGCAAAAATAGCAGATTTTGGATTGTCCCGAGGTCAAGAGGTGTATGTGAAAAAGACAATGGGAAGGC
TCCCAGTGCGCTGGATGGCCATCGAGTCACTGAATTACAGTGTGTACACAACCAACAGTGATGTATGGTCCTATGGTGTGTTACTATGGG
AGATTGTTAGCTTAGGAGGCACACCCTACTGCGGGATGACTTGTGCAGAACTCTACGAGAAGCTGCCCCAGGGCTACAGACTGGAGAAGC
CCCTGAACTGTGATGATGAGGTGTATGATCTAATGAGACAATGCTGGCGGGAGAAGCCTTATGAGAGGCCATCATTTGCCCAGATATTGG
TGTCCTTAAACAGAATGTTAGAGGAGCGAAAGACCTACGTGAATACCACGCTTTATGAGAAGTTTACTTATGCAGGAATTGACTGTTCTG
CTGAAGAAGCGGCCTAGGACAGAACATCTGTATACCCTCTGTTTCCCTTTCACTGGCATGGGAGACCCTTGACACCTGCTGAGAAAACAT
GCCTCTGCCAAAGGATGTGATATATAAGTGTACATATGTGCTGTACACCTGGGACCTTCACCACTGTAGATCCCATGCATGGATCTATGT
AGTATGCTCTGACTCTAATAGGACTGTATATACTGTTTTAAGAATGGGCTGAAATCAGAATGCCTGTTTGTGGTTTCATATGCAATAATA
TATTTTTTTAAAAATGTGGACTTCATAGGAAGGCGTGAGTACAATTAGTATAATGCATAACTCATTGTTGTCCTAGATATTTTGATATTT
ACCTTTATGTTGAATGCTATTAAATGTTTTCCTGTGTCAAAGTAAAATATTGTTAATAAACCTAACAATGACCCTGATAGTACAGGTTAA

>100712_100712_2_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000322831_TEK_chr9_27197313_ENST00000406359_length(amino acids)=786AA_BP=203
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSE
VITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLG
CEVDDKDDDILLNLVGCENSVTEGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLHPR
EQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAVISWTILDGYSISSITIRYKVQGKNEDQHVDVKIKNATITQYQ
LKGLEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNV
REEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCK
LGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAAR
NILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLE

--------------------------------------------------------------
>100712_100712_3_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000322831_TEK_chr9_27197313_ENST00000519097_length(transcript)=3079nt_BP=876nt
CCTGTTCGCAGCTGCGGCAGTGAGTATGTGTGTGACGGACCCCCGCCGCCCGCGGCTCGGGACCCCTGCCTACCCTCCTTCTTGCCCGCC
GGGCTGTGGAACTAGCGCGTGCCCCCTCGCCGGCCTCGACGTCTCCCGTCCGCCCCTCACTCGTGGCAGGGCGCAGCTCCTGGAGAATCT
GAGCATGGGGAATAAAGTCAGGAAGGATCGCAAGTGAGGATTATATTAATATGATAATTAGCACGCTTCAAGGTTACTGACTTTTTATGA
TGTTTGGTGGCTATGAGACTATAGAAGCATACGAAGATGATCTTTATCGAGATGAGTCATCTAGTGAACTGAGTGTTGATAGTGAGGTGG
AATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGAAGAAAAGAACTCTGGGAATT
CGGAATCTTCGAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCTGTCAGATGGGTCAGAGGTCA
TCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAGCACAAGAAAATGCCCATGGTCTTTCTTCTT
CTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAGATCAGGTGTAATCCGAGAGG
TCATGATTATAGAGGTCAGTTCAAGTGAAGAGGAAGAGAGCACCATTTCAGAAGGTGATAATGTGGAAAGCTGGATGCTACTGGGATGTG
AAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGGACTCCCTCCTCCAAGAGGTCTAA
ATCTCCTGCCTAAAAGTCAGACCACTCTAAATTTGACCTGGCAACCAATATTTCCAAGCTCGGAAGATGACTTTTATGTTGAAGTGGAGA
GAAGGTCTGTGCAAAAAAGTGATCAGCAGAATATTAAAGTTCCAGGCAACTTGACTTCGGTGCTACTTAACAACTTACATCCCAGGGAGC
AGTACGTGGTCCGAGCTAGAGTCAACACCAAGGCCCAGGGGGAATGGAGTGAAGATCTCACTGCTTGGACCCTTAGTGACATTCTTCCTC
CTCAACCAGAAAACATCAAGATTTCCAACATTACACACTCCTCAGCTGTGATTTCTTGGACAATATTGGATGGCTATTCTATTTCTTCTA
TTACTATCCGTTACAAGGTTCAAGGCAAGAATGAAGACCAGCACGTTGATGTGAAGATAAAGAATGCCACCATCACTCAGTATCAGCTCA
AGGGCCTAGAGCCTGAAACAGCATACCAGGTGGACATTTTTGCAGAGAACAACATAGGGTCAAGCAACCCAGCCTTTTCTCATGAACTGG
TGACCCTCCCAGAATCTCAAGCACCAGCGGACCTCGGAGGGGGGAAGATGCTGCTTATAGCCATCCTTGGCTCTGCTGGAATGACCTGCC
TGACTGTGCTGTTGGCCTTTCTGATCATATTGCAATTGAAGAGGGCAAATGTGCAAAGGAGAATGGCCCAAGCCTTCCAAAACAGGGAAG
AACCAGCTGTGCAGTTCAACTCAGGGACTCTGGCCCTAAACAGGAAGGTCAAAAACAACCCAGATCCTACAATTTATCCAGTGCTTGACT
GGAATGACATCAAATTTCAAGATGTGATTGGGGAGGGCAATTTTGGCCAAGTTCTTAAGGCGCGCATCAAGAAGGATGGGTTACGGATGG
ATGCTGCCATCAAAAGAATGAAAGAATATGCCTCCAAAGATGATCACAGGGACTTTGCAGGAGAACTGGAAGTTCTTTGTAAACTTGGAC
ACCATCCAAACATCATCAATCTCTTAGGAGCATGTGAACATCGAGGCTACTTGTACCTGGCCATTGAGTACGCGCCCCATGGAAACCTTC
TGGACTTCCTTCGCAAGAGCCGTGTGCTGGAGACGGACCCAGCATTTGCCATTGCCAATAGCACCGCGTCCACACTGTCCTCCCAGCAGC
TCCTTCACTTCGCTGCCGACGTGGCCCGGGGCATGGACTACTTGAGCCAAAAACAGTTTATCCACAGGGATCTGGCTGCCAGAAACATTT
TAGTTGGTGAAAACTATGTGGCAAAAATAGCAGATTTTGGATTGTCCCGAGGTCAAGAGGTGTATGTGAAAAAGACAATGGGAAGGCTCC
CAGTGCGCTGGATGGCCATCGAGTCACTGAATTACAGTGTGTACACAACCAACAGTGATGTATGGTCCTATGGTGTGTTACTATGGGAGA
TTGTTAGCTTAGGAGGCACACCCTACTGCGGGATGACTTGTGCAGAACTCTACGAGAAGCTGCCCCAGGGCTACAGACTGGAGAAGCCCC
TGAACTGTGATGATGAGGTGTATGATCTAATGAGACAATGCTGGCGGGAGAAGCCTTATGAGAGGCCATCATTTGCCCAGATATTGGTGT
CCTTAAACAGAATGTTAGAGGAGCGAAAGACCTACGTGAATACCACGCTTTATGAGAAGTTTACTTATGCAGGAATTGACTGTTCTGCTG
AAGAAGCGGCCTAGGACAGAACATCTGTATACCCTCTGTTTCCCTTTCACTGGCATGGGAGACCCTTGACACCTGCTGAGAAAACATGCC
TCTGCCAAAGGATGTGATATATAAGTGTACATATGTGCTGTACACCTGGGACCTTCACCACTGTAGATCCCATGCATGGATCTATGTAGT
ATGCTCTGACTCTAATAGGACTGTATATACTGTTTTAAGAATGGGCTGAAATCAGAATGCCTGTTTGTGGTTTCATATGCAATAATATAT
TTTTTTAAAAATGTGGACTTCATAGGAAGGCGTGAGTACAATTAGTATAATGCATAACTCATTGTTGTCCTAGATATTTTGATATTTACC
TTTATGTTGAATGCTATTAAATGTTTTCCTGTGTCAAAGTAAAATATTGTTAATAAACCTAACAATGACCCTGATAGTACAGGTTAAGTG

>100712_100712_3_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000322831_TEK_chr9_27197313_ENST00000519097_length(amino acids)=785AA_BP=203
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSE
VITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLG
CEVDDKDDDILLNLVGCENSVTEGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLHPR
EQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAVISWTILDGYSISSITIRYKVQGKNEDQHVDVKIKNATITQYQ
LKGLEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNR
EEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKL
GHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARN
ILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEK

--------------------------------------------------------------
>100712_100712_4_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000336755_TEK_chr9_27197313_ENST00000380036_length(transcript)=3410nt_BP=716nt
CTCCTTACCTCATTTGTCCTCGCCCCTCCCCGTCCCTCTACGCGTTTTGGTTCCCGGTTGGTGCTTCCTGTTCGCAGCTGCGGCACTTCA
AGGTTACTGACTTTTTATGATGTTTGGTGGCTATGAGACTATAGAAGCATACGAAGATGATCTTTATCGAGATGAGTCATCTAGTGAACT
GAGTGTTGATAGTGAGGTGGAATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGA
AGAAAAGAACTCTGGGAATTCGGAATCTTCGAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCT
GTCAGATGGGTCAGAGGTCATCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAGCACAAGAAAA
TGCCCATGGTCTTTCTTCTTCTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAG
ATCAGGTGTAATCCGAGAGGTCATGATTATAGAGGTCAGTTCAAGTGAAGAGGAAGAGAGCACCATTTCAGAAGGTGATAATGTGGAAAG
CTGGATGCTACTGGGATGTGAAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGGACT
CCCTCCTCCAAGAGGTCTAAATCTCCTGCCTAAAAGTCAGACCACTCTAAATTTGACCTGGCAACCAATATTTCCAAGCTCGGAAGATGA
CTTTTATGTTGAAGTGGAGAGAAGGTCTGTGCAAAAAAGTGATCAGCAGAATATTAAAGTTCCAGGCAACTTGACTTCGGTGCTACTTAA
CAACTTACATCCCAGGGAGCAGTACGTGGTCCGAGCTAGAGTCAACACCAAGGCCCAGGGGGAATGGAGTGAAGATCTCACTGCTTGGAC
CCTTAGTGACATTCTTCCTCCTCAACCAGAAAACATCAAGATTTCCAACATTACACACTCCTCAGCTGTGATTTCTTGGACAATATTGGA
TGGCTATTCTATTTCTTCTATTACTATCCGTTACAAGGTTCAAGGCAAGAATGAAGACCAGCACGTTGATGTGAAGATAAAGAATGCCAC
CATCACTCAGTATCAGCTCAAGGGCCTAGAGCCTGAAACAGCATACCAGGTGGACATTTTTGCAGAGAACAACATAGGGTCAAGCAACCC
AGCCTTTTCTCATGAACTGGTGACCCTCCCAGAATCTCAAGCACCAGCGGACCTCGGAGGGGGGAAGATGCTGCTTATAGCCATCCTTGG
CTCTGCTGGAATGACCTGCCTGACTGTGCTGTTGGCCTTTCTGATCATATTGCAATTGAAGAGGGCAAATGTGCAAAGGAGAATGGCCCA
AGCCTTCCAAAACGTGAGGGAAGAACCAGCTGTGCAGTTCAACTCAGGGACTCTGGCCCTAAACAGGAAGGTCAAAAACAACCCAGATCC
TACAATTTATCCAGTGCTTGACTGGAATGACATCAAATTTCAAGATGTGATTGGGGAGGGCAATTTTGGCCAAGTTCTTAAGGCGCGCAT
CAAGAAGGATGGGTTACGGATGGATGCTGCCATCAAAAGAATGAAAGAATATGCCTCCAAAGATGATCACAGGGACTTTGCAGGAGAACT
GGAAGTTCTTTGTAAACTTGGACACCATCCAAACATCATCAATCTCTTAGGAGCATGTGAACATCGAGGCTACTTGTACCTGGCCATTGA
GTACGCGCCCCATGGAAACCTTCTGGACTTCCTTCGCAAGAGCCGTGTGCTGGAGACGGACCCAGCATTTGCCATTGCCAATAGCACCGC
GTCCACACTGTCCTCCCAGCAGCTCCTTCACTTCGCTGCCGACGTGGCCCGGGGCATGGACTACTTGAGCCAAAAACAGTTTATCCACAG
GGATCTGGCTGCCAGAAACATTTTAGTTGGTGAAAACTATGTGGCAAAAATAGCAGATTTTGGATTGTCCCGAGGTCAAGAGGTGTATGT
GAAAAAGACAATGGGAAGGCTCCCAGTGCGCTGGATGGCCATCGAGTCACTGAATTACAGTGTGTACACAACCAACAGTGATGTATGGTC
CTATGGTGTGTTACTATGGGAGATTGTTAGCTTAGGAGGCACACCCTACTGCGGGATGACTTGTGCAGAACTCTACGAGAAGCTGCCCCA
GGGCTACAGACTGGAGAAGCCCCTGAACTGTGATGATGAGGTGTATGATCTAATGAGACAATGCTGGCGGGAGAAGCCTTATGAGAGGCC
ATCATTTGCCCAGATATTGGTGTCCTTAAACAGAATGTTAGAGGAGCGAAAGACCTACGTGAATACCACGCTTTATGAGAAGTTTACTTA
TGCAGGAATTGACTGTTCTGCTGAAGAAGCGGCCTAGGACAGAACATCTGTATACCCTCTGTTTCCCTTTCACTGGCATGGGAGACCCTT
GACACCTGCTGAGAAAACATGCCTCTGCCAAAGGATGTGATATATAAGTGTACATATGTGCTGTACACCTGGGACCTTCACCACTGTAGA
TCCCATGCATGGATCTATGTAGTATGCTCTGACTCTAATAGGACTGTATATACTGTTTTAAGAATGGGCTGAAATCAGAATGCCTGTTTG
TGGTTTCATATGCAATAATATATTTTTTTAAAAATGTGGACTTCATAGGAAGGCGTGAGTACAATTAGTATAATGCATAACTCATTGTTG
TCCTAGATATTTTGATATTTACCTTTATGTTGAATGCTATTAAATGTTTTCCTGTGTCAAAGTAAAATATTGTTAATAAACCTAACAATG
ACCCTGATAGTACAGGTTAAGTGAGAGAACTATATGAATTCTAACAAGTCATAGGTTAATATTTAAGACACTGAAAAATCTAAGTGATAT
AAATCAGATTCTTCTCTCTCAATTTTATCCCTCACCTGTAGCAGCCAGTCCCGTTTCATTTAGTCATGTGACCACTCTGTCTTGTGTTTC
CACAGCCTGCAAGTCAGTCCAGGATGCTAACATCTAAAAATAGACTTAAATCTCATTGCTTACAAGCCTAAGAATCTTTAGAGAAGTATA
CATAAGTTTAGGATAAAATAATGGGATTTTCTTTTCTTTTCTCTGGTAATATTGACTTGTATATTTTAAGAAATAACAGAAAGCCTGGGT
GACATTTGGGAGACATGTGACATTTATATATTGAATTAATATCCCTACATGTATTGCACATTGTAAAAAGTTTTAGTTTTGATGAGTTGT

>100712_100712_4_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000336755_TEK_chr9_27197313_ENST00000380036_length(amino acids)=786AA_BP=203
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSE
VITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLG
CEVDDKDDDILLNLVGCENSVTEGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLHPR
EQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAVISWTILDGYSISSITIRYKVQGKNEDQHVDVKIKNATITQYQ
LKGLEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNV
REEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCK
LGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAAR
NILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLE

--------------------------------------------------------------
>100712_100712_5_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000336755_TEK_chr9_27197313_ENST00000406359_length(transcript)=2981nt_BP=716nt
CTCCTTACCTCATTTGTCCTCGCCCCTCCCCGTCCCTCTACGCGTTTTGGTTCCCGGTTGGTGCTTCCTGTTCGCAGCTGCGGCACTTCA
AGGTTACTGACTTTTTATGATGTTTGGTGGCTATGAGACTATAGAAGCATACGAAGATGATCTTTATCGAGATGAGTCATCTAGTGAACT
GAGTGTTGATAGTGAGGTGGAATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGA
AGAAAAGAACTCTGGGAATTCGGAATCTTCGAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCT
GTCAGATGGGTCAGAGGTCATCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAGCACAAGAAAA
TGCCCATGGTCTTTCTTCTTCTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAG
ATCAGGTGTAATCCGAGAGGTCATGATTATAGAGGTCAGTTCAAGTGAAGAGGAAGAGAGCACCATTTCAGAAGGTGATAATGTGGAAAG
CTGGATGCTACTGGGATGTGAAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGGACT
CCCTCCTCCAAGAGGTCTAAATCTCCTGCCTAAAAGTCAGACCACTCTAAATTTGACCTGGCAACCAATATTTCCAAGCTCGGAAGATGA
CTTTTATGTTGAAGTGGAGAGAAGGTCTGTGCAAAAAAGTGATCAGCAGAATATTAAAGTTCCAGGCAACTTGACTTCGGTGCTACTTAA
CAACTTACATCCCAGGGAGCAGTACGTGGTCCGAGCTAGAGTCAACACCAAGGCCCAGGGGGAATGGAGTGAAGATCTCACTGCTTGGAC
CCTTAGTGACATTCTTCCTCCTCAACCAGAAAACATCAAGATTTCCAACATTACACACTCCTCAGCTGTGATTTCTTGGACAATATTGGA
TGGCTATTCTATTTCTTCTATTACTATCCGTTACAAGGTTCAAGGCAAGAATGAAGACCAGCACGTTGATGTGAAGATAAAGAATGCCAC
CATCACTCAGTATCAGCTCAAGGGCCTAGAGCCTGAAACAGCATACCAGGTGGACATTTTTGCAGAGAACAACATAGGGTCAAGCAACCC
AGCCTTTTCTCATGAACTGGTGACCCTCCCAGAATCTCAAGCACCAGCGGACCTCGGAGGGGGGAAGATGCTGCTTATAGCCATCCTTGG
CTCTGCTGGAATGACCTGCCTGACTGTGCTGTTGGCCTTTCTGATCATATTGCAATTGAAGAGGGCAAATGTGCAAAGGAGAATGGCCCA
AGCCTTCCAAAACGTGAGGGAAGAACCAGCTGTGCAGTTCAACTCAGGGACTCTGGCCCTAAACAGGAAGGTCAAAAACAACCCAGATCC
TACAATTTATCCAGTGCTTGACTGGAATGACATCAAATTTCAAGATGTGATTGGGGAGGGCAATTTTGGCCAAGTTCTTAAGGCGCGCAT
CAAGAAGGATGGGTTACGGATGGATGCTGCCATCAAAAGAATGAAAGAATATGCCTCCAAAGATGATCACAGGGACTTTGCAGGAGAACT
GGAAGTTCTTTGTAAACTTGGACACCATCCAAACATCATCAATCTCTTAGGAGCATGTGAACATCGAGGCTACTTGTACCTGGCCATTGA
GTACGCGCCCCATGGAAACCTTCTGGACTTCCTTCGCAAGAGCCGTGTGCTGGAGACGGACCCAGCATTTGCCATTGCCAATAGCACCGC
GTCCACACTGTCCTCCCAGCAGCTCCTTCACTTCGCTGCCGACGTGGCCCGGGGCATGGACTACTTGAGCCAAAAACAGTTTATCCACAG
GGATCTGGCTGCCAGAAACATTTTAGTTGGTGAAAACTATGTGGCAAAAATAGCAGATTTTGGATTGTCCCGAGGTCAAGAGGTGTATGT
GAAAAAGACAATGGGAAGGCTCCCAGTGCGCTGGATGGCCATCGAGTCACTGAATTACAGTGTGTACACAACCAACAGTGATGTATGGTC
CTATGGTGTGTTACTATGGGAGATTGTTAGCTTAGGAGGCACACCCTACTGCGGGATGACTTGTGCAGAACTCTACGAGAAGCTGCCCCA
GGGCTACAGACTGGAGAAGCCCCTGAACTGTGATGATGAGGTGTATGATCTAATGAGACAATGCTGGCGGGAGAAGCCTTATGAGAGGCC
ATCATTTGCCCAGATATTGGTGTCCTTAAACAGAATGTTAGAGGAGCGAAAGACCTACGTGAATACCACGCTTTATGAGAAGTTTACTTA
TGCAGGAATTGACTGTTCTGCTGAAGAAGCGGCCTAGGACAGAACATCTGTATACCCTCTGTTTCCCTTTCACTGGCATGGGAGACCCTT
GACACCTGCTGAGAAAACATGCCTCTGCCAAAGGATGTGATATATAAGTGTACATATGTGCTGTACACCTGGGACCTTCACCACTGTAGA
TCCCATGCATGGATCTATGTAGTATGCTCTGACTCTAATAGGACTGTATATACTGTTTTAAGAATGGGCTGAAATCAGAATGCCTGTTTG
TGGTTTCATATGCAATAATATATTTTTTTAAAAATGTGGACTTCATAGGAAGGCGTGAGTACAATTAGTATAATGCATAACTCATTGTTG
TCCTAGATATTTTGATATTTACCTTTATGTTGAATGCTATTAAATGTTTTCCTGTGTCAAAGTAAAATATTGTTAATAAACCTAACAATG
ACCCTGATAGTACAGGTTAAGTGAGAGAACTATATGAATTCTAACAAGTCATAGGTTAATATTTAAGACACTGAAAAATCTAAGTGATAT

>100712_100712_5_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000336755_TEK_chr9_27197313_ENST00000406359_length(amino acids)=786AA_BP=203
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSE
VITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLG
CEVDDKDDDILLNLVGCENSVTEGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLHPR
EQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAVISWTILDGYSISSITIRYKVQGKNEDQHVDVKIKNATITQYQ
LKGLEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNV
REEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCK
LGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAAR
NILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLE

--------------------------------------------------------------
>100712_100712_6_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000336755_TEK_chr9_27197313_ENST00000519097_length(transcript)=2919nt_BP=716nt
CTCCTTACCTCATTTGTCCTCGCCCCTCCCCGTCCCTCTACGCGTTTTGGTTCCCGGTTGGTGCTTCCTGTTCGCAGCTGCGGCACTTCA
AGGTTACTGACTTTTTATGATGTTTGGTGGCTATGAGACTATAGAAGCATACGAAGATGATCTTTATCGAGATGAGTCATCTAGTGAACT
GAGTGTTGATAGTGAGGTGGAATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGA
AGAAAAGAACTCTGGGAATTCGGAATCTTCGAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCT
GTCAGATGGGTCAGAGGTCATCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAGCACAAGAAAA
TGCCCATGGTCTTTCTTCTTCTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAG
ATCAGGTGTAATCCGAGAGGTCATGATTATAGAGGTCAGTTCAAGTGAAGAGGAAGAGAGCACCATTTCAGAAGGTGATAATGTGGAAAG
CTGGATGCTACTGGGATGTGAAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGGACT
CCCTCCTCCAAGAGGTCTAAATCTCCTGCCTAAAAGTCAGACCACTCTAAATTTGACCTGGCAACCAATATTTCCAAGCTCGGAAGATGA
CTTTTATGTTGAAGTGGAGAGAAGGTCTGTGCAAAAAAGTGATCAGCAGAATATTAAAGTTCCAGGCAACTTGACTTCGGTGCTACTTAA
CAACTTACATCCCAGGGAGCAGTACGTGGTCCGAGCTAGAGTCAACACCAAGGCCCAGGGGGAATGGAGTGAAGATCTCACTGCTTGGAC
CCTTAGTGACATTCTTCCTCCTCAACCAGAAAACATCAAGATTTCCAACATTACACACTCCTCAGCTGTGATTTCTTGGACAATATTGGA
TGGCTATTCTATTTCTTCTATTACTATCCGTTACAAGGTTCAAGGCAAGAATGAAGACCAGCACGTTGATGTGAAGATAAAGAATGCCAC
CATCACTCAGTATCAGCTCAAGGGCCTAGAGCCTGAAACAGCATACCAGGTGGACATTTTTGCAGAGAACAACATAGGGTCAAGCAACCC
AGCCTTTTCTCATGAACTGGTGACCCTCCCAGAATCTCAAGCACCAGCGGACCTCGGAGGGGGGAAGATGCTGCTTATAGCCATCCTTGG
CTCTGCTGGAATGACCTGCCTGACTGTGCTGTTGGCCTTTCTGATCATATTGCAATTGAAGAGGGCAAATGTGCAAAGGAGAATGGCCCA
AGCCTTCCAAAACAGGGAAGAACCAGCTGTGCAGTTCAACTCAGGGACTCTGGCCCTAAACAGGAAGGTCAAAAACAACCCAGATCCTAC
AATTTATCCAGTGCTTGACTGGAATGACATCAAATTTCAAGATGTGATTGGGGAGGGCAATTTTGGCCAAGTTCTTAAGGCGCGCATCAA
GAAGGATGGGTTACGGATGGATGCTGCCATCAAAAGAATGAAAGAATATGCCTCCAAAGATGATCACAGGGACTTTGCAGGAGAACTGGA
AGTTCTTTGTAAACTTGGACACCATCCAAACATCATCAATCTCTTAGGAGCATGTGAACATCGAGGCTACTTGTACCTGGCCATTGAGTA
CGCGCCCCATGGAAACCTTCTGGACTTCCTTCGCAAGAGCCGTGTGCTGGAGACGGACCCAGCATTTGCCATTGCCAATAGCACCGCGTC
CACACTGTCCTCCCAGCAGCTCCTTCACTTCGCTGCCGACGTGGCCCGGGGCATGGACTACTTGAGCCAAAAACAGTTTATCCACAGGGA
TCTGGCTGCCAGAAACATTTTAGTTGGTGAAAACTATGTGGCAAAAATAGCAGATTTTGGATTGTCCCGAGGTCAAGAGGTGTATGTGAA
AAAGACAATGGGAAGGCTCCCAGTGCGCTGGATGGCCATCGAGTCACTGAATTACAGTGTGTACACAACCAACAGTGATGTATGGTCCTA
TGGTGTGTTACTATGGGAGATTGTTAGCTTAGGAGGCACACCCTACTGCGGGATGACTTGTGCAGAACTCTACGAGAAGCTGCCCCAGGG
CTACAGACTGGAGAAGCCCCTGAACTGTGATGATGAGGTGTATGATCTAATGAGACAATGCTGGCGGGAGAAGCCTTATGAGAGGCCATC
ATTTGCCCAGATATTGGTGTCCTTAAACAGAATGTTAGAGGAGCGAAAGACCTACGTGAATACCACGCTTTATGAGAAGTTTACTTATGC
AGGAATTGACTGTTCTGCTGAAGAAGCGGCCTAGGACAGAACATCTGTATACCCTCTGTTTCCCTTTCACTGGCATGGGAGACCCTTGAC
ACCTGCTGAGAAAACATGCCTCTGCCAAAGGATGTGATATATAAGTGTACATATGTGCTGTACACCTGGGACCTTCACCACTGTAGATCC
CATGCATGGATCTATGTAGTATGCTCTGACTCTAATAGGACTGTATATACTGTTTTAAGAATGGGCTGAAATCAGAATGCCTGTTTGTGG
TTTCATATGCAATAATATATTTTTTTAAAAATGTGGACTTCATAGGAAGGCGTGAGTACAATTAGTATAATGCATAACTCATTGTTGTCC
TAGATATTTTGATATTTACCTTTATGTTGAATGCTATTAAATGTTTTCCTGTGTCAAAGTAAAATATTGTTAATAAACCTAACAATGACC

>100712_100712_6_ZCCHC7-TEK_ZCCHC7_chr9_37126939_ENST00000336755_TEK_chr9_27197313_ENST00000519097_length(amino acids)=785AA_BP=203
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSE
VITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLG
CEVDDKDDDILLNLVGCENSVTEGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLHPR
EQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAVISWTILDGYSISSITIRYKVQGKNEDQHVDVKIKNATITQYQ
LKGLEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNR
EEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKL
GHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARN
ILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEK

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Fusion Gene PPI Analysis for ZCCHC7-TEK


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZCCHC7-TEK


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZCCHC7-TEK


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource