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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZEB1-TAOK3 (FusionGDB2 ID:100861)

Fusion Gene Summary for ZEB1-TAOK3

check button Fusion gene summary
Fusion gene informationFusion gene name: ZEB1-TAOK3
Fusion gene ID: 100861
HgeneTgene
Gene symbol

ZEB1

TAOK3

Gene ID

6935

51347

Gene namezinc finger E-box binding homeobox 1TAO kinase 3
SynonymsAREB6|BZP|DELTAEF1|FECD6|NIL2A|PPCD3|TCF8|ZFHEP|ZFHX1ADPK|JIK|MAP3K18|hKFC-A
Cytomap

10p11.22

12q24.23

Type of geneprotein-codingprotein-coding
Descriptionzinc finger E-box-binding homeobox 1delta-crystallin enhancer binding factor 1negative regulator of IL2posterior polymorphous corneal dystrophy 3transcription factor 8 (represses interleukin 2 expression)zinc finger homeodomain enhancer-binding proteserine/threonine-protein kinase TAO3CTCL-associated antigen HD-CL-09JNK/SAPK-inhibitory kinaseSTE20-like kinasecutaneous T-cell lymphoma-associated antigen HD-CL-09dendritic cell-derived protein kinasejun kinase-inhibitory kinasekinase from chicken
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000559858, ENST00000320985, 
ENST00000361642, ENST00000542815, 
ENST00000560721, ENST00000446923, 
ENST00000392533, ENST00000419821, 
ENST00000536979, ENST00000537952, 
ENST00000543709, 
Fusion gene scores* DoF score11 X 5 X 8=44013 X 15 X 5=975
# samples 1316
** MAII scorelog2(13/440*10)=-1.7589919004962
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/975*10)=-2.60733031374961
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZEB1 [Title/Abstract] AND TAOK3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZEB1(31608221)-TAOK3(118651915), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneZEB1

GO:0000122

negative regulation of transcription by RNA polymerase II

23765923|23814079

HgeneZEB1

GO:0045892

negative regulation of transcription, DNA-templated

20418909

TgeneTAOK3

GO:0006468

protein phosphorylation

10559204

TgeneTAOK3

GO:0006974

cellular response to DNA damage stimulus

17396146

TgeneTAOK3

GO:0046329

negative regulation of JNK cascade

10559204

TgeneTAOK3

GO:0046777

protein autophosphorylation

10559204


check buttonFusion gene breakpoints across ZEB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TAOK3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-A4MJZEB1chr10

31608221

+TAOK3chr12

118651915

-


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Fusion Gene ORF analysis for ZEB1-TAOK3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000559858ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
3UTR-3CDSENST00000559858ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
3UTR-intronENST00000559858ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-
3UTR-intronENST00000559858ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
3UTR-intronENST00000559858ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000320985ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000320985ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000320985ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000361642ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000361642ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000361642ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000542815ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000542815ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000542815ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000560721ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000560721ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
5CDS-intronENST00000560721ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000320985ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000320985ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000361642ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000361642ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000542815ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000542815ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000560721ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
In-frameENST00000560721ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
intron-3CDSENST00000446923ENST00000392533ZEB1chr10

31608221

+TAOK3chr12

118651915

-
intron-3CDSENST00000446923ENST00000419821ZEB1chr10

31608221

+TAOK3chr12

118651915

-
intron-intronENST00000446923ENST00000536979ZEB1chr10

31608221

+TAOK3chr12

118651915

-
intron-intronENST00000446923ENST00000537952ZEB1chr10

31608221

+TAOK3chr12

118651915

-
intron-intronENST00000446923ENST00000543709ZEB1chr10

31608221

+TAOK3chr12

118651915

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000320985ZEB1chr1031608221+ENST00000419821TAOK3chr12118651915-34181681102221703
ENST00000320985ZEB1chr1031608221+ENST00000392533TAOK3chr12118651915-34181681102221703
ENST00000361642ZEB1chr1031608221+ENST00000419821TAOK3chr12118651915-3371121632174703
ENST00000361642ZEB1chr1031608221+ENST00000392533TAOK3chr12118651915-3371121632174703
ENST00000560721ZEB1chr1031608221+ENST00000419821TAOK3chr12118651915-333181232134703
ENST00000560721ZEB1chr1031608221+ENST00000392533TAOK3chr12118651915-333181232134703
ENST00000542815ZEB1chr1031608221+ENST00000419821TAOK3chr12118651915-332171132124703
ENST00000542815ZEB1chr1031608221+ENST00000392533TAOK3chr12118651915-332171132124703

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000320985ENST00000419821ZEB1chr1031608221+TAOK3chr12118651915-0.0076965460.9923035
ENST00000320985ENST00000392533ZEB1chr1031608221+TAOK3chr12118651915-0.0076965460.9923035
ENST00000361642ENST00000419821ZEB1chr1031608221+TAOK3chr12118651915-0.0083059730.99169403
ENST00000361642ENST00000392533ZEB1chr1031608221+TAOK3chr12118651915-0.0083059730.99169403
ENST00000560721ENST00000419821ZEB1chr1031608221+TAOK3chr12118651915-0.0085068770.99149317
ENST00000560721ENST00000392533ZEB1chr1031608221+TAOK3chr12118651915-0.0085068770.99149317
ENST00000542815ENST00000419821ZEB1chr1031608221+TAOK3chr12118651915-0.0086107240.99138933
ENST00000542815ENST00000392533ZEB1chr1031608221+TAOK3chr12118651915-0.0086107240.99138933

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Fusion Genomic Features for ZEB1-TAOK3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZEB1-TAOK3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:31608221/chr12:118651915)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTAOK3chr10:31608221chr12:118651915ENST00000392533821452_502214899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000392533821548_649214899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000392533821754_879214899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000419821821452_502214899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000419821821548_649214899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000419821821754_879214899.0Coiled coilOntology_term=ECO:0000255
TgeneTAOK3chr10:31608221chr12:118651915ENST00000392533821343_393214899.0Compositional biasNote=Ser-rich
TgeneTAOK3chr10:31608221chr12:118651915ENST00000419821821343_393214899.0Compositional biasNote=Ser-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19989_1124191125.0Compositional biasNote=Glu-rich (acidic)
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19989_1124191126.0Compositional biasNote=Glu-rich (acidic)
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19989_112401109.0Compositional biasNote=Glu-rich (acidic)
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18989_1124191058.0Compositional biasNote=Glu-rich (acidic)
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18989_1124191105.0Compositional biasNote=Glu-rich (acidic)
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19581_640191125.0DNA bindingNote=Homeobox%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19581_640191126.0DNA bindingNote=Homeobox%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19581_64001109.0DNA bindingNote=Homeobox%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18581_640191058.0DNA bindingNote=Homeobox%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18581_640191105.0DNA bindingNote=Homeobox%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19170_193191125.0Zinc fingerC2H2-type 1
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19200_222191125.0Zinc fingerC2H2-type 2
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19240_262191125.0Zinc fingerC2H2-type 3
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19268_292191125.0Zinc fingerC2H2-type 4%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19904_926191125.0Zinc fingerC2H2-type 5
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19932_954191125.0Zinc fingerC2H2-type 6
HgeneZEB1chr10:31608221chr12:118651915ENST00000320985+19960_981191125.0Zinc fingerC2H2-type 7%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19170_193191126.0Zinc fingerC2H2-type 1
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19200_222191126.0Zinc fingerC2H2-type 2
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19240_262191126.0Zinc fingerC2H2-type 3
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19268_292191126.0Zinc fingerC2H2-type 4%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19904_926191126.0Zinc fingerC2H2-type 5
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19932_954191126.0Zinc fingerC2H2-type 6
HgeneZEB1chr10:31608221chr12:118651915ENST00000361642+19960_981191126.0Zinc fingerC2H2-type 7%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19170_19301109.0Zinc fingerC2H2-type 1
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19200_22201109.0Zinc fingerC2H2-type 2
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19240_26201109.0Zinc fingerC2H2-type 3
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19268_29201109.0Zinc fingerC2H2-type 4%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19904_92601109.0Zinc fingerC2H2-type 5
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19932_95401109.0Zinc fingerC2H2-type 6
HgeneZEB1chr10:31608221chr12:118651915ENST00000446923+19960_98101109.0Zinc fingerC2H2-type 7%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18170_193191058.0Zinc fingerC2H2-type 1
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18200_222191058.0Zinc fingerC2H2-type 2
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18240_262191058.0Zinc fingerC2H2-type 3
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18268_292191058.0Zinc fingerC2H2-type 4%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18904_926191058.0Zinc fingerC2H2-type 5
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18932_954191058.0Zinc fingerC2H2-type 6
HgeneZEB1chr10:31608221chr12:118651915ENST00000542815+18960_981191058.0Zinc fingerC2H2-type 7%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18170_193191105.0Zinc fingerC2H2-type 1
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18200_222191105.0Zinc fingerC2H2-type 2
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18240_262191105.0Zinc fingerC2H2-type 3
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18268_292191105.0Zinc fingerC2H2-type 4%3B atypical
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18904_926191105.0Zinc fingerC2H2-type 5
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18932_954191105.0Zinc fingerC2H2-type 6
HgeneZEB1chr10:31608221chr12:118651915ENST00000560721+18960_981191105.0Zinc fingerC2H2-type 7%3B atypical
TgeneTAOK3chr10:31608221chr12:118651915ENST0000039253382124_277214899.0DomainProtein kinase
TgeneTAOK3chr10:31608221chr12:118651915ENST0000041982182124_277214899.0DomainProtein kinase
TgeneTAOK3chr10:31608221chr12:118651915ENST0000039253382130_38214899.0Nucleotide bindingATP
TgeneTAOK3chr10:31608221chr12:118651915ENST0000041982182130_38214899.0Nucleotide bindingATP


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Fusion Gene Sequence for ZEB1-TAOK3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>100861_100861_1_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000320985_TAOK3_chr12_118651915_ENST00000392533_length(transcript)=3418nt_BP=168nt
GTAAACCAGGTGCGGTGGGGAGGGGGGAGGGGTGGAGGCGGAGGGGTGGGGGGGAAGGGGGAGGGAGGGGGAGGAGGTGACTCGAGCATT
TAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGC
CGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACT
CCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGAC
GAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGA
AAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACA
GGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGG
AAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAG
ATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACT
ACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGG
AACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGC
ACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCA
TAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCT
TAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGC
AAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACG
ACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGA
GGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGA
AGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACA
GAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAG
TACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAG
ATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATG
AGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGC
AAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGG
AGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGA
GCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAA
AAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCT
TACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCT
GGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTT
TTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCA
AAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATT
TTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGT
GATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCT
GGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTC
ACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATA
TTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAG
TTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGC
ATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAA

>100861_100861_1_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000320985_TAOK3_chr12_118651915_ENST00000392533_length(amino acids)=703AA_BP=19
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>100861_100861_2_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000320985_TAOK3_chr12_118651915_ENST00000419821_length(transcript)=3418nt_BP=168nt
GTAAACCAGGTGCGGTGGGGAGGGGGGAGGGGTGGAGGCGGAGGGGTGGGGGGGAAGGGGGAGGGAGGGGGAGGAGGTGACTCGAGCATT
TAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGC
CGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACT
CCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGAC
GAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGA
AAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACA
GGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGG
AAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAG
ATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACT
ACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGG
AACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGC
ACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCA
TAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCT
TAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGC
AAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACG
ACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGA
GGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGA
AGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACA
GAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAG
TACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAG
ATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATG
AGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGC
AAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGG
AGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGA
GCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAA
AAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCT
TACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCT
GGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTT
TTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCA
AAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATT
TTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGT
GATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCT
GGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTC
ACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATA
TTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAG
TTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGC
ATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAA

>100861_100861_2_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000320985_TAOK3_chr12_118651915_ENST00000419821_length(amino acids)=703AA_BP=19
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>100861_100861_3_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000361642_TAOK3_chr12_118651915_ENST00000392533_length(transcript)=3371nt_BP=121nt
GGGGGGGAAGGGGGAGGGAGGGGGAGGAGGTGACTCGAGCATTTAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGC
AGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGCCGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCC
CAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACTCCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAA
AGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAA
GATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCA
CAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCC
GTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGAC
GAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCT
GAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTT
ACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAG
CTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCG
TCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAG
CAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAA
GAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCT
GAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCAC
GAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAG
TCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAA
AACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCC
ATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTT
ACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAG
AGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAG
GAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGA
GTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTA
TTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAG
GAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCAC
ATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTC
CATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTAT
TGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGC
TTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCG
CAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTT
ATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGG
GGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATC
ATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTT
GTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCC
TGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCT
CCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGAT
GAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTC

>100861_100861_3_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000361642_TAOK3_chr12_118651915_ENST00000392533_length(amino acids)=703AA_BP=19
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>100861_100861_4_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000361642_TAOK3_chr12_118651915_ENST00000419821_length(transcript)=3371nt_BP=121nt
GGGGGGGAAGGGGGAGGGAGGGGGAGGAGGTGACTCGAGCATTTAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGC
AGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGCCGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCC
CAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACTCCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAA
AGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAA
GATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCA
CAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCC
GTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGAC
GAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCT
GAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTT
ACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAG
CTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCG
TCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAG
CAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAA
GAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCT
GAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCAC
GAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAG
TCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAA
AACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCC
ATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTT
ACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAG
AGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAG
GAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGA
GTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTA
TTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAG
GAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCAC
ATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTC
CATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTAT
TGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGC
TTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCG
CAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTT
ATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGG
GGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATC
ATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTT
GTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCC
TGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCT
CCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGAT
GAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTC

>100861_100861_4_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000361642_TAOK3_chr12_118651915_ENST00000419821_length(amino acids)=703AA_BP=19
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>100861_100861_5_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000542815_TAOK3_chr12_118651915_ENST00000392533_length(transcript)=3321nt_BP=71nt
AAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGCCGCCCCT
TTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACTCCTTTAG
GAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGACGAGACCG
GCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAAT
ACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAAT
GGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCAT
GGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGT
ATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAA
CAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGAT
GTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCT
CAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAA
GGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAG
TCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCG
GATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAA
TTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCA
GAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACG
CATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCA
TGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGAC
CAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCA
GACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCA
AGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGA
GGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGC
TGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAG
AATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAA
AAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTT
ACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAA
ACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAA
AACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATA
ATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTT
TTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTAC
ATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGA
GTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAAT
CCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATT
TTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACA
CTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTC
ACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACA

>100861_100861_5_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000542815_TAOK3_chr12_118651915_ENST00000392533_length(amino acids)=703AA_BP=19
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>100861_100861_6_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000542815_TAOK3_chr12_118651915_ENST00000419821_length(transcript)=3321nt_BP=71nt
AAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGAAGCCGCCCCT
TTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAGACTCCTTTAG
GAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTCGACGAGACCG
GCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAAT
ACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAAT
GGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCAT
GGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGT
ATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAA
CAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGAT
GTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCT
CAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAA
GGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAG
TCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCG
GATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAA
TTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCA
GAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACG
CATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCA
TGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGAC
CAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCA
GACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCA
AGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGA
GGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGC
TGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAG
AATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAA
AAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTT
ACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAA
ACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAA
AACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATA
ATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTT
TTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTAC
ATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGA
GTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAAT
CCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATT
TTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACA
CTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTC
ACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACA

>100861_100861_6_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000542815_TAOK3_chr12_118651915_ENST00000419821_length(amino acids)=703AA_BP=19
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>100861_100861_7_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000560721_TAOK3_chr12_118651915_ENST00000392533_length(transcript)=3331nt_BP=81nt
ATTTAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGA
AGCCGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAG
ACTCCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTC
GACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAA
TGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGA
ACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGC
AGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGA
AAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCC
ACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGC
GGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACG
AGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTA
TCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTT
TCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGA
AGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACT
ACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAA
AGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTAC
AGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGC
ACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCA
AAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGA
AAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAG
ATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGA
TGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAG
AGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGG
AGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAA
AAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTC
TCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGT
GCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACA
GTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAA
GCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTT
ATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAAT
TGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCT
GCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAG
CTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTC
ATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTG
GAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATAT
TGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAA
AAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTCAGAGCTTTTAATTATATTTGTAAATAAAAGTGTTCATCAC

>100861_100861_7_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000560721_TAOK3_chr12_118651915_ENST00000392533_length(amino acids)=703AA_BP=19
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------
>100861_100861_8_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000560721_TAOK3_chr12_118651915_ENST00000419821_length(transcript)=3331nt_BP=81nt
ATTTAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACGCGGAACGGA
AGCCGCCCCTTTTCAACATGAATGCAATGAGTGCCTTATATCACATTGCCCAGAATGACTCCCCAACGTTACAGTCTAATGAATGGACAG
ACTCCTTTAGGAGATTTGTTGATTACTGCTTGCAGAAAATACCTCAGGAAAGGCCAACATCAGCAGAACTATTAAGGCATGACTTTGTTC
GACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGCAGTTCGTGAGCTAGATAACCTACAGTACCGAAAAA
TGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGAGGATGAGGAAGACAGTGAACATGGAACCAGCCTGA
ACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAGCACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGC
AGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAGCACAATCAATTCCAGCTCCTCCGTCGTGCATAAGA
AAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCCGCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCC
ACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACGACAGATCCATGAGCATGAGCAGGAGAACGAGTTGC
GGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGATCGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACG
AGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCATCGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTA
TCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACAGATCTTGGCCCAGCAGAAGAAAGATTTGACAACTT
TCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGAAATGAATGAGGACCATAGCACACCCAAGAAAGAGA
AGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGAGGAAGCCCACCTTCTCACTCAACAGAGACTGTACT
ACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGTGGAGCAGCAGAACATTCGGGAGGAACTAAATAAAA
AGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCACCCGAGAGCTAGAGTACAGGCAGCTGCACACGTTAC
AGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCAGCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGC
ACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGAAATGCAAATTAAAAAACAGTTTCAGGACACTTGCA
AAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCCAAAGAATGAGCACAAAACAATCTTAAAGACACTGA
AAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTATAAATGAAATGATGGCCTCTCAAGCGTTACGGCTAG
ATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAATGGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGA
TGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTCTCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAG
AGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGAAAGGCAAGAGCGAGAGATTGAAACTTTTGACATGG
AGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGACTACAGATGAGATTAAATTTTTTGCCATTTACAAA
AAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCCCCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTC
TCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCAGGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGT
GCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATGTGATTCAAAATGTTTCAGTGAAAACTTTGGAGACA
GTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAAGCAATCACTCATTACCACCAATCTGTGAAAGTAAA
GCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCCTTACACCTTAACTAGCTGCTGCATTATTTTATTTT
ATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAAAGATTGAAAATTTGATACATTTTACAGAAACTAAT
TGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGGGTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCT
GCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTTCTGCTGTTGCAGAGGATGTGAATACACTTAAGGAG
CTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTATAGAAGGAATTTAAGGAGAGGTATTACTTATTTTC
ATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTCCTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTG
GAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTTCCCCTTCCTAAGTCCCATTTCTTGGTCATAAATAT
TGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAAAAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAA
AAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTCAGAGCTTTTAATTATATTTGTAAATAAAAGTGTTCATCAC

>100861_100861_8_ZEB1-TAOK3_ZEB1_chr10_31608221_ENST00000560721_TAOK3_chr12_118651915_ENST00000419821_length(amino acids)=703AA_BP=19
MADGPRCKRRKQANPRRNNAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPLRV
LIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGSQSSSVNSMQEVMDESS
SELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYK
RMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQ
YKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQNIREELNKKRTQKEME
HAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYK
ALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZEB1-TAOK3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZEB1-TAOK3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZEB1-TAOK3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource