Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ZFAND2B-ZFAND2B (FusionGDB2 ID:100894)

Fusion Gene Summary for ZFAND2B-ZFAND2B

Fusion gene summary

Fusion gene information	Fusion gene name: ZFAND2B-ZFAND2B
	Fusion gene ID: 100894
		Hgene	Tgene
	Gene symbol	ZFAND2B	ZFAND2B
	Gene ID	130617	130617
	Gene name	zinc finger AN1-type containing 2B	zinc finger AN1-type containing 2B
	Synonyms	AIRAPL	AIRAPL
	Cytomap	2q35	2q35
	Type of gene	protein-coding	protein-coding
	Description	AN1-type zinc finger protein 2BAIRAP-like proteinarsenite-inducible RNA-associated protein-like proteinzinc finger, AN1-type domain 2B	AN1-type zinc finger protein 2BAIRAP-like proteinarsenite-inducible RNA-associated protein-like proteinzinc finger, AN1-type domain 2B
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000468301, ENST00000289528, ENST00000409097, ENST00000409206, ENST00000409594, ENST00000409336, ENST00000409217, ENST00000409319, ENST00000409412, ENST00000444522,	ENST00000289528, ENST00000409097, ENST00000409206, ENST00000409217, ENST00000409336, ENST00000409412, ENST00000409594, ENST00000409319, ENST00000444522, ENST00000468301,
Fusion gene scores	* DoF score	2 X 4 X 2=16	2 X 4 X 1=8
	# samples	5	4
	** MAII score	log2(5/16*10)=1.64385618977472 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(4/8*10)=2.32192809488736
Context	PubMed: ZFAND2B [Title/Abstract] AND ZFAND2B [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ZFAND2B(220074145)-ZFAND2B(220073150), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across ZFAND2B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ZFAND2B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS5.0	N/A	AA490922	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
ChiTaRS5.0	N/A	AA491105	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
ChiTaRS5.0	N/A	AA513147	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
ChiTaRS5.0	N/A	AW968850	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+

Top

Fusion Gene ORF analysis for ZFAND2B-ZFAND2B

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-3CDS	ENST00000468301	ENST00000289528	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
3UTR-3CDS	ENST00000468301	ENST00000409097	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
3UTR-3CDS	ENST00000468301	ENST00000409206	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
3UTR-3CDS	ENST00000468301	ENST00000409217	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
3UTR-3CDS	ENST00000468301	ENST00000409336	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
3UTR-3CDS	ENST00000468301	ENST00000409412	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
3UTR-3CDS	ENST00000468301	ENST00000409594	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
3UTR-3UTR	ENST00000289528	ENST00000289528	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-3UTR	ENST00000289528	ENST00000409206	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-3UTR	ENST00000289528	ENST00000409594	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-3UTR	ENST00000409097	ENST00000289528	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-3UTR	ENST00000409097	ENST00000409206	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-3UTR	ENST00000409097	ENST00000409594	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-3UTR	ENST00000409206	ENST00000289528	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-3UTR	ENST00000409206	ENST00000409097	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-3UTR	ENST00000409206	ENST00000409594	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-3UTR	ENST00000409594	ENST00000289528	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-3UTR	ENST00000409594	ENST00000289528	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-3UTR	ENST00000409594	ENST00000409097	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-3UTR	ENST00000409594	ENST00000409206	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-3UTR	ENST00000409594	ENST00000409594	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-3UTR	ENST00000409594	ENST00000409594	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000289528	ENST00000409097	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000289528	ENST00000409217	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000289528	ENST00000409319	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000289528	ENST00000409336	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000289528	ENST00000409412	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000289528	ENST00000444522	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000289528	ENST00000468301	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409097	ENST00000409097	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409097	ENST00000409217	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409097	ENST00000409319	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409097	ENST00000409336	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409097	ENST00000409412	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409097	ENST00000444522	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409097	ENST00000468301	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409206	ENST00000409206	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409206	ENST00000409217	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409206	ENST00000409319	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409206	ENST00000409336	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409206	ENST00000409412	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409206	ENST00000444522	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409206	ENST00000468301	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409594	ENST00000409097	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409594	ENST00000409206	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409594	ENST00000409217	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409594	ENST00000409217	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409594	ENST00000409319	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409594	ENST00000409319	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409594	ENST00000409336	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409594	ENST00000409336	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409594	ENST00000409412	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409594	ENST00000409412	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409594	ENST00000444522	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409594	ENST00000444522	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000409594	ENST00000468301	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
3UTR-intron	ENST00000409594	ENST00000468301	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
3UTR-intron	ENST00000468301	ENST00000409319	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
3UTR-intron	ENST00000468301	ENST00000444522	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
3UTR-intron	ENST00000468301	ENST00000468301	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-3UTR	ENST00000409336	ENST00000289528	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
5CDS-3UTR	ENST00000409336	ENST00000409206	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
5CDS-3UTR	ENST00000409336	ENST00000409594	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
5CDS-intron	ENST00000289528	ENST00000409319	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000289528	ENST00000444522	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000289528	ENST00000468301	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409097	ENST00000409319	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409097	ENST00000444522	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409097	ENST00000468301	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409206	ENST00000409319	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409206	ENST00000444522	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409206	ENST00000468301	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409217	ENST00000409319	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409217	ENST00000444522	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409217	ENST00000468301	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409319	ENST00000409319	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409319	ENST00000444522	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409319	ENST00000468301	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409336	ENST00000409097	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
5CDS-intron	ENST00000409336	ENST00000409217	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
5CDS-intron	ENST00000409336	ENST00000409319	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
5CDS-intron	ENST00000409336	ENST00000409319	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409336	ENST00000409336	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
5CDS-intron	ENST00000409336	ENST00000409412	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
5CDS-intron	ENST00000409336	ENST00000444522	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
5CDS-intron	ENST00000409336	ENST00000444522	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409336	ENST00000468301	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
5CDS-intron	ENST00000409336	ENST00000468301	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409412	ENST00000409319	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409412	ENST00000444522	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409412	ENST00000468301	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409594	ENST00000409319	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409594	ENST00000444522	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000409594	ENST00000468301	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000444522	ENST00000409319	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000444522	ENST00000444522	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
5CDS-intron	ENST00000444522	ENST00000468301	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000289528	ENST00000289528	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000289528	ENST00000409097	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000289528	ENST00000409206	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000289528	ENST00000409217	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000289528	ENST00000409336	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000289528	ENST00000409412	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000289528	ENST00000409594	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409097	ENST00000289528	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409097	ENST00000409097	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409097	ENST00000409206	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409097	ENST00000409217	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409097	ENST00000409336	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409097	ENST00000409412	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409097	ENST00000409594	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409206	ENST00000289528	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409206	ENST00000409097	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409206	ENST00000409206	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409206	ENST00000409217	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409206	ENST00000409336	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409206	ENST00000409412	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409206	ENST00000409594	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409217	ENST00000289528	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409217	ENST00000409097	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409217	ENST00000409206	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409217	ENST00000409217	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409217	ENST00000409336	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409217	ENST00000409412	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409217	ENST00000409594	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409319	ENST00000289528	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409319	ENST00000409097	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409319	ENST00000409206	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409319	ENST00000409217	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409319	ENST00000409336	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409319	ENST00000409594	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409336	ENST00000289528	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409336	ENST00000409097	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409336	ENST00000409206	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409336	ENST00000409217	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409336	ENST00000409336	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409336	ENST00000409412	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409336	ENST00000409594	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409412	ENST00000289528	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409412	ENST00000409097	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409412	ENST00000409206	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409412	ENST00000409217	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409412	ENST00000409336	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409412	ENST00000409412	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409412	ENST00000409594	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409594	ENST00000289528	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409594	ENST00000409097	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409594	ENST00000409206	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409594	ENST00000409217	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409594	ENST00000409336	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409594	ENST00000409412	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000409594	ENST00000409594	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000444522	ENST00000289528	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000444522	ENST00000409097	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000444522	ENST00000409206	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000444522	ENST00000409217	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000444522	ENST00000409336	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000444522	ENST00000409412	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
Frame-shift	ENST00000444522	ENST00000409594	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
In-frame	ENST00000409319	ENST00000409412	ZFAND2B	chr2	220072696	+	ZFAND2B	chr2	220072729	-
intron-3UTR	ENST00000289528	ENST00000289528	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000289528	ENST00000409097	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000289528	ENST00000409594	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409097	ENST00000289528	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409097	ENST00000409097	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409097	ENST00000409594	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409206	ENST00000289528	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409206	ENST00000409206	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409206	ENST00000409594	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409217	ENST00000289528	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409217	ENST00000289528	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409217	ENST00000409097	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409217	ENST00000409206	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409217	ENST00000409594	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409217	ENST00000409594	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409319	ENST00000289528	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409319	ENST00000289528	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409319	ENST00000409097	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409319	ENST00000409206	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409319	ENST00000409594	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409319	ENST00000409594	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409336	ENST00000289528	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409336	ENST00000409097	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409336	ENST00000409594	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409412	ENST00000289528	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409412	ENST00000289528	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409412	ENST00000409097	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000409412	ENST00000409206	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409412	ENST00000409594	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000409412	ENST00000409594	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000444522	ENST00000289528	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000444522	ENST00000289528	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000444522	ENST00000409097	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000444522	ENST00000409206	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000444522	ENST00000409594	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000444522	ENST00000409594	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000468301	ENST00000289528	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000468301	ENST00000289528	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000468301	ENST00000409097	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-3UTR	ENST00000468301	ENST00000409206	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000468301	ENST00000409594	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-3UTR	ENST00000468301	ENST00000409594	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000289528	ENST00000409206	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000289528	ENST00000409217	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000289528	ENST00000409319	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000289528	ENST00000409336	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000289528	ENST00000409412	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000289528	ENST00000444522	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000289528	ENST00000468301	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409097	ENST00000409206	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409097	ENST00000409217	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409097	ENST00000409319	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409097	ENST00000409336	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409097	ENST00000409412	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409097	ENST00000444522	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409097	ENST00000468301	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409206	ENST00000409097	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409206	ENST00000409217	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409206	ENST00000409319	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409206	ENST00000409336	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409206	ENST00000409412	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409206	ENST00000444522	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409206	ENST00000468301	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409217	ENST00000409097	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409217	ENST00000409206	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409217	ENST00000409217	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409217	ENST00000409217	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409217	ENST00000409319	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409217	ENST00000409319	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409217	ENST00000409336	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409217	ENST00000409336	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409217	ENST00000409412	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409217	ENST00000409412	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409217	ENST00000444522	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409217	ENST00000444522	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409217	ENST00000468301	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409217	ENST00000468301	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409319	ENST00000409097	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409319	ENST00000409206	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409319	ENST00000409217	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409319	ENST00000409217	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409319	ENST00000409319	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409319	ENST00000409319	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409319	ENST00000409336	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409319	ENST00000409336	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409319	ENST00000409412	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409319	ENST00000409412	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409319	ENST00000444522	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409319	ENST00000444522	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409319	ENST00000468301	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409319	ENST00000468301	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409336	ENST00000409206	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409336	ENST00000409217	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409336	ENST00000409319	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409336	ENST00000409336	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409336	ENST00000409412	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409336	ENST00000444522	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409336	ENST00000468301	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409412	ENST00000409097	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409412	ENST00000409206	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409412	ENST00000409217	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409412	ENST00000409217	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409412	ENST00000409319	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409412	ENST00000409319	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409412	ENST00000409336	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409412	ENST00000409336	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409412	ENST00000409412	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409412	ENST00000409412	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409412	ENST00000444522	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409412	ENST00000444522	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000409412	ENST00000468301	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000409412	ENST00000468301	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000444522	ENST00000409097	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000444522	ENST00000409206	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000444522	ENST00000409217	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000444522	ENST00000409217	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000444522	ENST00000409319	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000444522	ENST00000409319	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000444522	ENST00000409336	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000444522	ENST00000409336	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000444522	ENST00000409412	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000444522	ENST00000409412	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000444522	ENST00000444522	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000444522	ENST00000444522	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000444522	ENST00000468301	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000444522	ENST00000468301	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000468301	ENST00000409097	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000468301	ENST00000409206	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000468301	ENST00000409217	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000468301	ENST00000409217	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000468301	ENST00000409319	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000468301	ENST00000409319	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000468301	ENST00000409336	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000468301	ENST00000409336	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000468301	ENST00000409412	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000468301	ENST00000409412	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000468301	ENST00000444522	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000468301	ENST00000444522	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+
intron-intron	ENST00000468301	ENST00000468301	ZFAND2B	chr2	220074145	-	ZFAND2B	chr2	220073150	+
intron-intron	ENST00000468301	ENST00000468301	ZFAND2B	chr2	220073150	-	ZFAND2B	chr2	220074145	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

Top

Fusion Genomic Features for ZFAND2B-ZFAND2B

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for ZFAND2B-ZFAND2B

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:220074145/chr2:220073150)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

197_216

258.0

Domain

UIM 1

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

221_240

258.0

Domain

UIM 2

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

197_216

177.0

Domain

UIM 1

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

221_240

177.0

Domain

UIM 2

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

197_216

258.0

Domain

UIM 1

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

221_240

258.0

Domain

UIM 2

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

197_216

177.0

Domain

UIM 1

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

221_240

177.0

Domain

UIM 2

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

254_257

258.0

Motif

CAAX motif

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

254_257

177.0

Motif

CAAX motif

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

254_257

258.0

Motif

CAAX motif

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

254_257

177.0

Motif

CAAX motif

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

141_151

258.0

Region

VCP/p97-interacting motif (VIM)

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

141_151

177.0

Region

VCP/p97-interacting motif (VIM)

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

141_151

258.0

Region

VCP/p97-interacting motif (VIM)

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

141_151

177.0

Region

VCP/p97-interacting motif (VIM)

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

7_52

258.0

Zinc finger

AN1-type 1

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

97_145

258.0

Zinc finger

AN1-type 2

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

7_52

177.0

Zinc finger

AN1-type 1

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

97_145

177.0

Zinc finger

AN1-type 2

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

7_52

258.0

Zinc finger

AN1-type 1

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

97_145

258.0

Zinc finger

AN1-type 2

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

7_52

177.0

Zinc finger

AN1-type 1

Tgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

97_145

177.0

Zinc finger

AN1-type 2

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

197_216

258.0

Domain

UIM 1

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

221_240

258.0

Domain

UIM 2

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

197_216

177.0

Domain

UIM 1

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

221_240

177.0

Domain

UIM 2

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

197_216

258.0

Domain

UIM 1

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

221_240

258.0

Domain

UIM 2

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

197_216

177.0

Domain

UIM 1

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

221_240

177.0

Domain

UIM 2

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

254_257

258.0

Motif

CAAX motif

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

254_257

177.0

Motif

CAAX motif

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

254_257

258.0

Motif

CAAX motif

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

254_257

177.0

Motif

CAAX motif

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

141_151

258.0

Region

VCP/p97-interacting motif (VIM)

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

141_151

177.0

Region

VCP/p97-interacting motif (VIM)

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

141_151

258.0

Region

VCP/p97-interacting motif (VIM)

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

141_151

177.0

Region

VCP/p97-interacting motif (VIM)

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

7_52

258.0

Zinc finger

AN1-type 1

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000289528

97_145

258.0

Zinc finger

AN1-type 2

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

7_52

177.0

Zinc finger

AN1-type 1

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409206

97_145

177.0

Zinc finger

AN1-type 2

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

7_52

258.0

Zinc finger

AN1-type 1

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409336

97_145

258.0

Zinc finger

AN1-type 2

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

7_52

177.0

Zinc finger

AN1-type 1

Hgene

ZFAND2B

chr2:220072696

chr2:220072729

ENST00000409594

97_145

177.0

Zinc finger

AN1-type 2

Top

Fusion Gene Sequence for ZFAND2B-ZFAND2B

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

Top

Fusion Gene PPI Analysis for ZFAND2B-ZFAND2B

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for ZFAND2B-ZFAND2B

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for ZFAND2B-ZFAND2B

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source