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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZFYVE1-DENND4A (FusionGDB2 ID:101159)

Fusion Gene Summary for ZFYVE1-DENND4A

check button Fusion gene summary
Fusion gene informationFusion gene name: ZFYVE1-DENND4A
Fusion gene ID: 101159
HgeneTgene
Gene symbol

ZFYVE1

DENND4A

Gene ID

53349

10260

Gene namezinc finger FYVE-type containing 1DENN domain containing 4A
SynonymsDFCP1|PPP1R172|SR3|TAFF1|ZNFN2A1IRLB|MYCPBP
Cytomap

14q24.2

15q22.31

Type of geneprotein-codingprotein-coding
Descriptionzinc finger FYVE domain-containing protein 1double FYVE-containing protein 1phosphoinositide-binding protein SR3protein phosphatase 1, regulatory subunit 172tandem FYVE fingers-1 proteinzinc finger protein, subfamily 2A, member 1zinc finger, FYVE doC-myc promoter-binding proteinDENN domain-containing protein 4ADENN/MADD domain containing 4Ac-myc promoter binding protein
Modification date2020032720200313
UniProtAcc.

Q7Z401

Ensembl transtripts involved in fusion geneENST00000318876, ENST00000553891, 
ENST00000556143, ENST00000394207, 
ENST00000554145, ENST00000555072, 
ENST00000567323, ENST00000431932, 
ENST00000443035, 
Fusion gene scores* DoF score5 X 6 X 3=906 X 7 X 4=168
# samples 68
** MAII scorelog2(6/90*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/168*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZFYVE1 [Title/Abstract] AND DENND4A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZFYVE1(73459850)-DENND4A(65998562), # samples:1
ZFYVE1(73459851)-DENND4A(65998562), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneZFYVE1

GO:0009267

cellular response to starvation

25578879

HgeneZFYVE1

GO:0010923

negative regulation of phosphatase activity

19389623

HgeneZFYVE1

GO:0016236

macroautophagy

25578879


check buttonFusion gene breakpoints across ZFYVE1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DENND4A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-DU-A7TD-01AZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
ChimerDB4LGGTCGA-DU-A7TDZFYVE1chr14

73459850

-DENND4Achr15

65998562

-


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Fusion Gene ORF analysis for ZFYVE1-DENND4A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000318876ENST00000567323ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
5CDS-intronENST00000318876ENST00000567323ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
5CDS-intronENST00000553891ENST00000567323ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
5CDS-intronENST00000553891ENST00000567323ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
5CDS-intronENST00000556143ENST00000567323ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
5CDS-intronENST00000556143ENST00000567323ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
In-frameENST00000318876ENST00000431932ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
In-frameENST00000318876ENST00000431932ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
In-frameENST00000318876ENST00000443035ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
In-frameENST00000318876ENST00000443035ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
In-frameENST00000553891ENST00000431932ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
In-frameENST00000553891ENST00000431932ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
In-frameENST00000553891ENST00000443035ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
In-frameENST00000553891ENST00000443035ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
In-frameENST00000556143ENST00000431932ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
In-frameENST00000556143ENST00000431932ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
In-frameENST00000556143ENST00000443035ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
In-frameENST00000556143ENST00000443035ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
intron-3CDSENST00000394207ENST00000431932ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
intron-3CDSENST00000394207ENST00000431932ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
intron-3CDSENST00000394207ENST00000443035ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
intron-3CDSENST00000394207ENST00000443035ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
intron-3CDSENST00000554145ENST00000431932ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
intron-3CDSENST00000554145ENST00000431932ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
intron-3CDSENST00000554145ENST00000443035ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
intron-3CDSENST00000554145ENST00000443035ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
intron-3CDSENST00000555072ENST00000431932ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
intron-3CDSENST00000555072ENST00000431932ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
intron-3CDSENST00000555072ENST00000443035ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
intron-3CDSENST00000555072ENST00000443035ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
intron-intronENST00000394207ENST00000567323ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
intron-intronENST00000394207ENST00000567323ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
intron-intronENST00000554145ENST00000567323ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
intron-intronENST00000554145ENST00000567323ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-
intron-intronENST00000555072ENST00000567323ZFYVE1chr14

73459851

-DENND4Achr15

65998562

-
intron-intronENST00000555072ENST00000567323ZFYVE1chr14

73459850

-DENND4Achr15

65998562

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000553891ZFYVE1chr1473459850-ENST00000443035DENND4Achr1565998562-6821181861555851656
ENST00000553891ZFYVE1chr1473459850-ENST00000431932DENND4Achr1565998562-5531181861554561613
ENST00000318876ZFYVE1chr1473459850-ENST00000443035DENND4Achr1565998562-6846184364056101656
ENST00000318876ZFYVE1chr1473459850-ENST00000431932DENND4Achr1565998562-5556184364054811613
ENST00000556143ZFYVE1chr1473459850-ENST00000443035DENND4Achr1565998562-6927192472156911656
ENST00000556143ZFYVE1chr1473459850-ENST00000431932DENND4Achr1565998562-5637192472155621613
ENST00000553891ZFYVE1chr1473459851-ENST00000443035DENND4Achr1565998562-6821181861555851656
ENST00000553891ZFYVE1chr1473459851-ENST00000431932DENND4Achr1565998562-5531181861554561613
ENST00000318876ZFYVE1chr1473459851-ENST00000443035DENND4Achr1565998562-6846184364056101656
ENST00000318876ZFYVE1chr1473459851-ENST00000431932DENND4Achr1565998562-5556184364054811613
ENST00000556143ZFYVE1chr1473459851-ENST00000443035DENND4Achr1565998562-6927192472156911656
ENST00000556143ZFYVE1chr1473459851-ENST00000431932DENND4Achr1565998562-5637192472155621613

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000553891ENST00000443035ZFYVE1chr1473459850-DENND4Achr1565998562-0.0002608970.9997391
ENST00000553891ENST00000431932ZFYVE1chr1473459850-DENND4Achr1565998562-0.0002837860.9997162
ENST00000318876ENST00000443035ZFYVE1chr1473459850-DENND4Achr1565998562-0.0002651920.9997348
ENST00000318876ENST00000431932ZFYVE1chr1473459850-DENND4Achr1565998562-0.0002828330.9997172
ENST00000556143ENST00000443035ZFYVE1chr1473459850-DENND4Achr1565998562-0.0002904380.99970955
ENST00000556143ENST00000431932ZFYVE1chr1473459850-DENND4Achr1565998562-0.0003200890.9996799
ENST00000553891ENST00000443035ZFYVE1chr1473459851-DENND4Achr1565998562-0.0002608970.9997391
ENST00000553891ENST00000431932ZFYVE1chr1473459851-DENND4Achr1565998562-0.0002837860.9997162
ENST00000318876ENST00000443035ZFYVE1chr1473459851-DENND4Achr1565998562-0.0002651920.9997348
ENST00000318876ENST00000431932ZFYVE1chr1473459851-DENND4Achr1565998562-0.0002828330.9997172
ENST00000556143ENST00000443035ZFYVE1chr1473459851-DENND4Achr1565998562-0.0002904380.99970955
ENST00000556143ENST00000431932ZFYVE1chr1473459851-DENND4Achr1565998562-0.0003200890.9996799

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Fusion Genomic Features for ZFYVE1-DENND4A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZFYVE1-DENND4A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:73459850/chr15:65998562)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DENND4A

Q7Z401

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter. {ECO:0000269|PubMed:20937701, ECO:0000269|PubMed:8056341}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDENND4Achr14:73459850chr15:65998562ENST0000043193213321183_11896511864.0Compositional biasNote=Poly-Glu
TgeneDENND4Achr14:73459850chr15:65998562ENST0000044303513331183_11896511907.0Compositional biasNote=Poly-Glu
TgeneDENND4Achr14:73459851chr15:65998562ENST0000043193213321183_11896511864.0Compositional biasNote=Poly-Glu
TgeneDENND4Achr14:73459851chr15:65998562ENST0000044303513331183_11896511907.0Compositional biasNote=Poly-Glu
TgeneDENND4Achr14:73459850chr15:65998562ENST000004319321332917_9336511864.0MotifBipartite nuclear localization signal
TgeneDENND4Achr14:73459850chr15:65998562ENST000004430351333917_9336511907.0MotifBipartite nuclear localization signal
TgeneDENND4Achr14:73459851chr15:65998562ENST000004319321332917_9336511864.0MotifBipartite nuclear localization signal
TgeneDENND4Achr14:73459851chr15:65998562ENST000004430351333917_9336511907.0MotifBipartite nuclear localization signal
TgeneDENND4Achr14:73459850chr15:65998562ENST000004319321332772_8086511864.0RepeatNote=PPR 1
TgeneDENND4Achr14:73459850chr15:65998562ENST000004319321332809_8436511864.0RepeatNote=PPR 2
TgeneDENND4Achr14:73459850chr15:65998562ENST000004430351333772_8086511907.0RepeatNote=PPR 1
TgeneDENND4Achr14:73459850chr15:65998562ENST000004430351333809_8436511907.0RepeatNote=PPR 2
TgeneDENND4Achr14:73459851chr15:65998562ENST000004319321332772_8086511864.0RepeatNote=PPR 1
TgeneDENND4Achr14:73459851chr15:65998562ENST000004319321332809_8436511864.0RepeatNote=PPR 2
TgeneDENND4Achr14:73459851chr15:65998562ENST000004430351333772_8086511907.0RepeatNote=PPR 1
TgeneDENND4Achr14:73459851chr15:65998562ENST000004430351333809_8436511907.0RepeatNote=PPR 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZFYVE1chr14:73459850chr15:65998562ENST00000394207-19416_7770363.0RegionRequired for localization in the lipid droplets
HgeneZFYVE1chr14:73459850chr15:65998562ENST00000555072-19416_7770363.0RegionRequired for localization in the lipid droplets
HgeneZFYVE1chr14:73459850chr15:65998562ENST00000556143-412416_777401778.0RegionRequired for localization in the lipid droplets
HgeneZFYVE1chr14:73459851chr15:65998562ENST00000394207-19416_7770363.0RegionRequired for localization in the lipid droplets
HgeneZFYVE1chr14:73459851chr15:65998562ENST00000555072-19416_7770363.0RegionRequired for localization in the lipid droplets
HgeneZFYVE1chr14:73459851chr15:65998562ENST00000556143-412416_777401778.0RegionRequired for localization in the lipid droplets
HgeneZFYVE1chr14:73459850chr15:65998562ENST00000394207-19598_6590363.0Zinc fingerFYVE-type 1
HgeneZFYVE1chr14:73459850chr15:65998562ENST00000394207-19715_7750363.0Zinc fingerFYVE-type 2
HgeneZFYVE1chr14:73459850chr15:65998562ENST00000555072-19598_6590363.0Zinc fingerFYVE-type 1
HgeneZFYVE1chr14:73459850chr15:65998562ENST00000555072-19715_7750363.0Zinc fingerFYVE-type 2
HgeneZFYVE1chr14:73459850chr15:65998562ENST00000556143-412598_659401778.0Zinc fingerFYVE-type 1
HgeneZFYVE1chr14:73459850chr15:65998562ENST00000556143-412715_775401778.0Zinc fingerFYVE-type 2
HgeneZFYVE1chr14:73459851chr15:65998562ENST00000394207-19598_6590363.0Zinc fingerFYVE-type 1
HgeneZFYVE1chr14:73459851chr15:65998562ENST00000394207-19715_7750363.0Zinc fingerFYVE-type 2
HgeneZFYVE1chr14:73459851chr15:65998562ENST00000555072-19598_6590363.0Zinc fingerFYVE-type 1
HgeneZFYVE1chr14:73459851chr15:65998562ENST00000555072-19715_7750363.0Zinc fingerFYVE-type 2
HgeneZFYVE1chr14:73459851chr15:65998562ENST00000556143-412598_659401778.0Zinc fingerFYVE-type 1
HgeneZFYVE1chr14:73459851chr15:65998562ENST00000556143-412715_775401778.0Zinc fingerFYVE-type 2
TgeneDENND4Achr14:73459850chr15:65998562ENST000004319321332192_3646511864.0DomainuDENN
TgeneDENND4Achr14:73459850chr15:65998562ENST000004319321332385_5216511864.0DomaincDENN
TgeneDENND4Achr14:73459850chr15:65998562ENST00000431932133242_2006511864.0DomainMABP
TgeneDENND4Achr14:73459850chr15:65998562ENST000004319321332523_6416511864.0DomaindDENN
TgeneDENND4Achr14:73459850chr15:65998562ENST000004430351333192_3646511907.0DomainuDENN
TgeneDENND4Achr14:73459850chr15:65998562ENST000004430351333385_5216511907.0DomaincDENN
TgeneDENND4Achr14:73459850chr15:65998562ENST00000443035133342_2006511907.0DomainMABP
TgeneDENND4Achr14:73459850chr15:65998562ENST000004430351333523_6416511907.0DomaindDENN
TgeneDENND4Achr14:73459851chr15:65998562ENST000004319321332192_3646511864.0DomainuDENN
TgeneDENND4Achr14:73459851chr15:65998562ENST000004319321332385_5216511864.0DomaincDENN
TgeneDENND4Achr14:73459851chr15:65998562ENST00000431932133242_2006511864.0DomainMABP
TgeneDENND4Achr14:73459851chr15:65998562ENST000004319321332523_6416511864.0DomaindDENN
TgeneDENND4Achr14:73459851chr15:65998562ENST000004430351333192_3646511907.0DomainuDENN
TgeneDENND4Achr14:73459851chr15:65998562ENST000004430351333385_5216511907.0DomaincDENN
TgeneDENND4Achr14:73459851chr15:65998562ENST00000443035133342_2006511907.0DomainMABP
TgeneDENND4Achr14:73459851chr15:65998562ENST000004430351333523_6416511907.0DomaindDENN


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Fusion Gene Sequence for ZFYVE1-DENND4A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>101159_101159_1_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000318876_DENND4A_chr15_65998562_ENST00000431932_length(transcript)=5556nt_BP=1843nt
TGTTAGTCCGAGCTGGGAGAAGTTCACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGA
GGGTGGCGGAGATGGAGATGAGGATGGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCG
CCTTGCTGCGGCCGAGCTTCTCAGTGGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCA
TTACCAAAACTTTGTAGCTGATGTCCAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCC
AAGTCAATTTTGACCACATCTTTGCTTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAG
AGGCAGCAAATTAAAAATTTGAACATTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGT
GGAAGTTTCGTGCAGTCTTCAGACTCAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTAC
CAGCGTGAGTATGAGTGCCCAGACTTCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGAC
TGATGAAGCTATCTTTGAGTGTGATGAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAA
CCATGAGCGGATAAGACTCAAACCTGGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAG
GGCAATAGTGAGGTGCCAGACCTGCAAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCC
TGTTACTGTGTACAATGTCAGTAATCTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAA
GGTTGTGAGTTTCCTCCTAGTAGACGAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGA
TCAGCATCTGAAAGTGGTTTCCATTTTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGT
CTTTAAAACCTCCCCGACCCAGGAGTCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGA
AGGGCTCCTGGGGGCCACCGTGAATCTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAAC
TCATGCAGACCGGCTGCATAACGACCTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGC
CACCACTGCTCGCTGTGGCCTGGATGTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACT
GGGCTCTGATCATCCCTCAGAGGTGCCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCAT
TCACTACAAGGGAACGAGGACTTACAACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCAC
CCGTTCTCCCCGGCACCCGGGAGTCATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGA
ATCTTTCAAAAGTGAACACACTGTTTTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTA
TAATGGATTTCCAGTTCTTAGGAACAATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAG
TAGTCCTAATAGCCCTTTGCCCATGTTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCC
TCAGATGTGGTCTAGGTGTCTACTGCGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGT
CAGGGCTCTGAAAACAGCATATGATGTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTAT
GCAACTCTGTGGACAATATGATCAGCCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTAC
TTATGGTTATTATAATAAGGCTGTTTTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGT
TGTTTTAGGAGTAACACAGTTCAAAAGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGGTGGCCAGTCTGATCTTGG
ATATAATTCATTATCTAAAGATGAAGTTAGAAGAGGGGATACATCTACTGAAGACATTCAAGAAGAAAAAGATAAAAAAGGGAGTGATTG
TAGTTCCTTGTCAGAGAGTGAGAGTACAAAAGGAAGTGCTGATTGCCTTCCTAAGCTCAGTTATCAAAATTCTTCCAGTATCGTTCGCCT
CACTGGTACAAGTAACAACAGTGCTGGTAAAATATCAGGAGAAAGCATGGAAAGCACACCTGAGCTGCTCTTAATATCATCTCTTGAAGA
TACAAATGAAACACGAAACATTCAAAGTAGATGCTTCAGGAAAAGACATAAAAGTGACAATGAAACTAATTTGCAGCAGCAAGTGGTCTG
GGGAAATAGAAACCGTAATCTTAGTGGAGGGGTACTGATGGGATTTATGCTCAATAGAATTAACCAGGAAGCAACCCCTGGAGATATAGT
TGAAAAATTGGGAGCTGATGCAAAAATTCTTTCAAATGTTATCTCAAAAAGCACGAGACCAAATACTCTTGATATTGGGAAGCCACCTTT
AAGATCAAAAAGAGACAGTCTAGAAAAGGAATCTAGTGATGATGATACACCTTTTGATGGTTCTAACTATTTGGCAGATAAAGTGGATTC
TCCTGTTATTTTTGACTTAGAAGACTTAGACAGTGAAACAGATGTATCAAAAGCAGGATGTGTTGCTACACAAAATCCCAAGAGGATTCA
ACGTATGAACAGCAGCTTTTCAGTAAAACCTTTTGAAAAAACTGATGTCGCAACAGGATTTGATCCCCTCTCTCTTTTGGTTGCTGAGAC
TGAACAGCAGCAAAAAGAAGAAGAGGAGGAGGATGAAGATGATAGCAAAAGCATTTCAACACCATCTGCTAGGCGTGATTTAGCTGAAGA
AATTGTGATGTATATGAATAACATGAGCAGTCCTTTGACAAGTCGTACACCAAGCATTGATTTACAACGGGCATGTGATGATAAATTAAA
TAAGAAAAGTCCACCATTGGTCAAGGCATGCAGAAGATCTAGTCTGCCTCCTAATTCTCCTAAGCCAGTGAGACTTACCAAATCTAAAAG
TTACACAAAAAGTGAGGAGAAACCAAGGGATAGACTTTGGTCTTCTCCAGCCTTCTCACCTACTTGCCCATTTAGGGAAGAATCTCAGGA
TACATTAACCCACTCATCACCTTCATTTAACTTAGATACACTACTAGTACCTAAACTAGATGTTCTAAGAAACAGTATGTTCACTGCTGG
AAAAGGAGTTGCAGAGAAAGCAAGCAAATGGTATTCAAGATTCACCATGTACACCACATCATCTAAGGATCAAAGTTCTGATCGTACCAG
TCTTTCTTCAGTGGGAGCCCAGGATTCTGAATCTACCTCTTTAACAGATGAAGATGTCTGCCATGAGTTGGAAGGACCTATCTCCTCTCA
AGAGACCAGTGCTACTTCAGGGACTAAGAGAATTGATCTCAGCCGAATAAGCCTGGAAAGTTCTGCATCCTTGGAAGGATCTCTGTCGAA
GTTTGCCTTACCTGGGAAATCAGAAGTGACATCTTCCTTCAACGCGAGTAATACAAATATCTTCCAGAACTATGCAATGGAGGTTCTCAT
CTCAAGTTGCTCTCGGTGTAGAACTTGTGATTGTCTTGTCCATGATGAGGAAATCATGGCTGGCTGGACAGCAGATGATTCAAATCTCAA
TACTACATGCCCATTCTGTGGCAATATCTTCTTACCCTTTCTGAATATAGAAATAAGAGATTTAAGACGACCTGGAAGATACTTTCTAAA
GTCAAGCCCATCAACAGAAAATATGCACTTTCCATCCTCCATTTCAAGTCAGACGAGGCAGTCTTGCATTTCAACATCAGCCTCTGGTCT
TGACACATCTGCTCTCTCTGTTCAAGGGAATTTTGATCTAAATAGCAAATCTAAACTGCAGGAAAATTTTTGCACCCGAAGTATTCAGAT
CCCTGCTAATAGATCAAAAACAGCTATGTCTAAATGTCCAATATTTCCAATGGCCAGGAGTATTAGTACTTCTGGCCCCTTGGATAAGGA
AGATACTGGAAGACAGAAGCTCATTTCTACAGGCAGCCTGCCAGCTACTTTACAAGGAGCTACAGATTCTTTAGGTTTAGAATGGCACCT
TCCAAGTCCCGATCCTGTCACTGTTCCGTATCTTAGTCCTTTAGTGGTATGGAAAGAACTTGAAAGCTTATTGGAAAATGAAGGTGATCA
TGCAATAACAGTAGCAGACTTTGTGGACCATCATCCAATTGTTTTTTGGAACCTGGTATGGTATTTCAGACGTCTTGACTTGCCCAGTAA
CTTACCTGGATTGATTCTTTCTTCTGAGCACTGTAACAAGTATTCAAAGATTCCCCGCCACTGTATGTCTGAAGATAGCAAATATGTTTT
AATACAAATGTTATGGGACAATATGAAGTTACATCAGGATCCGGGACAGCCCTTGTACATTCTCTGGAATGCACACACCCAAAAATATCC
AATGGTCCATTTATTGCAAAAAAGTGATAACTCATTTAACCAGGAACTGTTGAAAAGTATGGTAAAAAGCATTAAAATGAATGATGTCTA
TGGACCAATGAGTCAGATTTTAGAGACACTGAATAAGTGTCCACATTTTAAAAGACAGAGGAGTTTATACAGAGAAATACTATTTCTCTC
ACTTGTGGCACTGGGAAGAGAAAACATTGATATAGATGCTTTTGATAAAGAGTACAAGATGGCATACGATCGTCTCACACCTAGTCAAGT
CAAGAGTACACACAACTGTGATAGACCACCAAGTACAGGGGTGATGGAATGTCGAAAAACCTTTGGAGAACCTTATCTTTAAGATGTATT

>101159_101159_1_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000318876_DENND4A_chr15_65998562_ENST00000431932_length(amino acids)=1613AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGT
SNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDNETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKL
GADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDGSNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMN
SSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSISTPSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKS
PPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSPTCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGV
AEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFAL
PGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSP
STENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTG
RQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPG
LILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPM

--------------------------------------------------------------
>101159_101159_2_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000318876_DENND4A_chr15_65998562_ENST00000443035_length(transcript)=6846nt_BP=1843nt
TGTTAGTCCGAGCTGGGAGAAGTTCACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGA
GGGTGGCGGAGATGGAGATGAGGATGGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCG
CCTTGCTGCGGCCGAGCTTCTCAGTGGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCA
TTACCAAAACTTTGTAGCTGATGTCCAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCC
AAGTCAATTTTGACCACATCTTTGCTTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAG
AGGCAGCAAATTAAAAATTTGAACATTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGT
GGAAGTTTCGTGCAGTCTTCAGACTCAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTAC
CAGCGTGAGTATGAGTGCCCAGACTTCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGAC
TGATGAAGCTATCTTTGAGTGTGATGAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAA
CCATGAGCGGATAAGACTCAAACCTGGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAG
GGCAATAGTGAGGTGCCAGACCTGCAAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCC
TGTTACTGTGTACAATGTCAGTAATCTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAA
GGTTGTGAGTTTCCTCCTAGTAGACGAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGA
TCAGCATCTGAAAGTGGTTTCCATTTTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGT
CTTTAAAACCTCCCCGACCCAGGAGTCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGA
AGGGCTCCTGGGGGCCACCGTGAATCTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAAC
TCATGCAGACCGGCTGCATAACGACCTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGC
CACCACTGCTCGCTGTGGCCTGGATGTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACT
GGGCTCTGATCATCCCTCAGAGGTGCCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCAT
TCACTACAAGGGAACGAGGACTTACAACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCAC
CCGTTCTCCCCGGCACCCGGGAGTCATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGA
ATCTTTCAAAAGTGAACACACTGTTTTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTA
TAATGGATTTCCAGTTCTTAGGAACAATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAG
TAGTCCTAATAGCCCTTTGCCCATGTTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCC
TCAGATGTGGTCTAGGTGTCTACTGCGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGT
CAGGGCTCTGAAAACAGCATATGATGTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTAT
GCAACTCTGTGGACAATATGATCAGCCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTAC
TTATGGTTATTATAATAAGGCTGTTTTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGT
TGTTTTAGGAGTAACACAGTTCAAAAGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGATGGCAGTGACCTGGATGC
TGTTAGTCATGGCAGCATGGATAGTGGTCATGGGACACACACTGTGGAGCAGGCACCTTTTAATACGGGTTTAATCAAAGTATATGCTAC
TGATGATAGATCTAGTACAGGTGGCCAGTCTGATCTTGGATATAATTCATTATCTAAAGATGAAGTTAGAAGAGGGGATACATCTACTGA
AGACATTCAAGAAGAAAAAGATAAAAAAGGGAGTGATTGTAGTTCCTTGTCAGAGAGTGAGAGTACAAAAGGAAGTGCTGATTGCCTTCC
TAAGCTCAGTTATCAAAATTCTTCCAGTATCGTTCGCCTCACTGGTACAAGTAACAACAGTGCTGGTAAAATATCAGGAGAAAGCATGGA
AAGCACACCTGAGCTGCTCTTAATATCATCTCTTGAAGATACAAATGAAACACGAAACATTCAAAGTAGATGCTTCAGGAAAAGACATAA
AAGTGACAATGAAACTAATTTGCAGCAGCAAGTGGTCTGGGGAAATAGAAACCGTAATCTTAGTGGAGGGGTACTGATGGGATTTATGCT
CAATAGAATTAACCAGGAAGCAACCCCTGGAGATATAGTTGAAAAATTGGGAGCTGATGCAAAAATTCTTTCAAATGTTATCTCAAAAAG
CACGAGACCAAATACTCTTGATATTGGGAAGCCACCTTTAAGATCAAAAAGAGACAGTCTAGAAAAGGAATCTAGTGATGATGATACACC
TTTTGATGGTTCTAACTATTTGGCAGATAAAGTGGATTCTCCTGTTATTTTTGACTTAGAAGACTTAGACAGTGAAACAGATGTATCAAA
AGCAGGATGTGTTGCTACACAAAATCCCAAGAGGATTCAACGTATGAACAGCAGCTTTTCAGTAAAACCTTTTGAAAAAACTGATGTCGC
AACAGGATTTGATCCCCTCTCTCTTTTGGTTGCTGAGACTGAACAGCAGCAAAAAGAAGAAGAGGAGGAGGATGAAGATGATAGCAAAAG
CATTTCAACACCATCTGCTAGGCGTGATTTAGCTGAAGAAATTGTGATGTATATGAATAACATGAGCAGTCCTTTGACAAGTCGTACACC
AAGCATTGATTTACAACGGGCATGTGATGATAAATTAAATAAGAAAAGTCCACCATTGGTCAAGGCATGCAGAAGATCTAGTCTGCCTCC
TAATTCTCCTAAGCCAGTGAGACTTACCAAATCTAAAAGTTACACAAAAAGTGAGGAGAAACCAAGGGATAGACTTTGGTCTTCTCCAGC
CTTCTCACCTACTTGCCCATTTAGGGAAGAATCTCAGGATACATTAACCCACTCATCACCTTCATTTAACTTAGATACACTACTAGTACC
TAAACTAGATGTTCTAAGAAACAGTATGTTCACTGCTGGAAAAGGAGTTGCAGAGAAAGCAAGCAAATGGTATTCAAGATTCACCATGTA
CACCACATCATCTAAGGATCAAAGTTCTGATCGTACCAGTCTTTCTTCAGTGGGAGCCCAGGATTCTGAATCTACCTCTTTAACAGATGA
AGATGTCTGCCATGAGTTGGAAGGACCTATCTCCTCTCAAGAGACCAGTGCTACTTCAGGGACTAAGAGAATTGATCTCAGCCGAATAAG
CCTGGAAAGTTCTGCATCCTTGGAAGGATCTCTGTCGAAGTTTGCCTTACCTGGGAAATCAGAAGTGACATCTTCCTTCAACGCGAGTAA
TACAAATATCTTCCAGAACTATGCAATGGAGGTTCTCATCTCAAGTTGCTCTCGGTGTAGAACTTGTGATTGTCTTGTCCATGATGAGGA
AATCATGGCTGGCTGGACAGCAGATGATTCAAATCTCAATACTACATGCCCATTCTGTGGCAATATCTTCTTACCCTTTCTGAATATAGA
AATAAGAGATTTAAGACGACCTGGAAGATACTTTCTAAAGTCAAGCCCATCAACAGAAAATATGCACTTTCCATCCTCCATTTCAAGTCA
GACGAGGCAGTCTTGCATTTCAACATCAGCCTCTGGTCTTGACACATCTGCTCTCTCTGTTCAAGGGAATTTTGATCTAAATAGCAAATC
TAAACTGCAGGAAAATTTTTGCACCCGAAGTATTCAGATCCCTGCTAATAGATCAAAAACAGCTATGTCTAAATGTCCAATATTTCCAAT
GGCCAGGAGTATTAGTACTTCTGGCCCCTTGGATAAGGAAGATACTGGAAGACAGAAGCTCATTTCTACAGGCAGCCTGCCAGCTACTTT
ACAAGGAGCTACAGATTCTTTAGGTTTAGAATGGCACCTTCCAAGTCCCGATCCTGTCACTGTTCCGTATCTTAGTCCTTTAGTGGTATG
GAAAGAACTTGAAAGCTTATTGGAAAATGAAGGTGATCATGCAATAACAGTAGCAGACTTTGTGGACCATCATCCAATTGTTTTTTGGAA
CCTGGTATGGTATTTCAGACGTCTTGACTTGCCCAGTAACTTACCTGGATTGATTCTTTCTTCTGAGCACTGTAACAAGTATTCAAAGAT
TCCCCGCCACTGTATGTCTGAAGATAGCAAATATGTTTTAATACAAATGTTATGGGACAATATGAAGTTACATCAGGATCCGGGACAGCC
CTTGTACATTCTCTGGAATGCACACACCCAAAAATATCCAATGGTCCATTTATTGCAAAAAAGTGATAACTCATTTAACCAGGAACTGTT
GAAAAGTATGGTAAAAAGCATTAAAATGAATGATGTCTATGGACCAATGAGTCAGATTTTAGAGACACTGAATAAGTGTCCACATTTTAA
AAGACAGAGGAGTTTATACAGAGAAATACTATTTCTCTCACTTGTGGCACTGGGAAGAGAAAACATTGATATAGATGCTTTTGATAAAGA
GTACAAGATGGCATACGATCGTCTCACACCTAGTCAAGTCAAGAGTACACACAACTGTGATAGACCACCAAGTACAGGGGTGATGGAATG
TCGAAAAACCTTTGGAGAACCTTATCTTTAAGATGTATTTGTATGTGTAAACATTCAATGTATATTGTATAGTCAGTGTATAAAATAACA
CTTTTAGACTCTAAATATTTTTTCTTCAATTTTTGAAAATACAATTTGTAAATGGTTCAAAAGACTCAGACAGCTTATGTACAGAATGTT
TGAAGAAGAGAATAGTGACAAGTGGGGAGAAAGCCACTTTGTTTCTCATTTCTTTTTTCTTCTTCTTTAACTCCCCTGTAATAGGAAATA
AAGTATTTTTGTGATGAGGAAATCCCTAAACAAAATTAGTTGCCATAAAATATGACAACTGCTTTATGGTTTCTTTTGGAAGAGACAGAT
TGAAAAATCATGAATGGAATCTAAACAGAAATGTCAGATGAACGTATTTCCTGTTTTCATAGACTATTCAAATGTTTTGACCATGAAGTT
GTATTATACATATTTTAAATTGTTTATAGTAAGTTGATATTTTTTTAATTTTTAAATTTAATATAGCAAACTTAAAATGAATTTAAACTT
AAGCAAGCAAGCGTGTATTTTCCTTGTCTGCTGCTATTTGAAGTAATTAGTACAGCTGCAGATCTCTCTGTGTATATCTATCTATATATA
TATTTTTTATTACTTGGGAGAATGAATTTTAAAATGTCAGTGCTAGTGTCAAGTGTTGTCCTAGGATTGCATGTTAGTACCCCTAAGCCT
GAGTGTGGGGAGTGAGTTATGCAAGGGTAGCGTGCACTGCCCAGACTGACTCATGGAGCCTTGTGCAAGGAGAGCCAGAGAGGTTCACTA
TACCATGACTCCAAAATTGTCTCTATTGCTAATAGATACGTATAGTATACAGGGAAAACAGCTTATAAATCCAAATATCAATTTAAATTT
TAATATTCTACATGAAAACTTACATTGGGAAATATGCAGACAAGTGATTATATTCCAAATTTTACCCTTATTTTAATATCTAAAATATTG
GGTATGATGCAAATTATACTATAGAATATTTATCTGAAATATGACTTACTGGGGTATTCTGTTAATACTATATATAAATATTCAGAATTT
TTTTCAAAAGTAGAAAAATTCCCCTCTAAAAGTACAGCCAGATAGATTTTCATCCATATTGAGGAACTTAGCTTTTTCAACAAGCTTCAG
AATCTGAAGTCTGTAGAATCTAAAATACAGAAATATCCAGAAATCAGACAATAAATTGAAAGTTTAGACATCATGAGTATTAAATAGCTT

>101159_101159_2_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000318876_DENND4A_chr15_65998562_ENST00000443035_length(amino acids)=1656AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSDGSDLDAVSHGSMDSGHGTHTVEQAPFNTGLIKVYATDDRSSTGGQSDLGYNSLSKDEVRRGDTSTEDIQ
EEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGTSNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDN
ETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKLGADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDG
SNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMNSSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSIST
PSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKSPPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSP
TCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVC
HELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFALPGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMA
GWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQ
ENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKEL
ESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYI
LWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKM

--------------------------------------------------------------
>101159_101159_3_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000553891_DENND4A_chr15_65998562_ENST00000431932_length(transcript)=5531nt_BP=1818nt
ACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGAGGGTGGCGGAGATGGAGATGAGGAT
GGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCGCCTTGCTGCGGCCGAGCTTCTCAGT
GGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCATTACCAAAACTTTGTAGCTGATGTC
CAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCCAAGTCAATTTTGACCACATCTTTGC
TTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAGAGGCAGCAAATTAAAAATTTGAACA
TTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGTGGAAGTTTCGTGCAGTCTTCAGACT
CAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTACCAGCGTGAGTATGAGTGCCCAGACT
TCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGACTGATGAAGCTATCTTTGAGTGTGAT
GAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAACCATGAGCGGATAAGACTCAAACCT
GGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAGGGCAATAGTGAGGTGCCAGACCTGC
AAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCCTGTTACTGTGTACAATGTCAGTAAT
CTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAAGGTTGTGAGTTTCCTCCTAGTAGAC
GAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGATCAGCATCTGAAAGTGGTTTCCATT
TTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGTCTTTAAAACCTCCCCGACCCAGGAG
TCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGAAGGGCTCCTGGGGGCCACCGTGAAT
CTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAACTCATGCAGACCGGCTGCATAACGAC
CTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGCCACCACTGCTCGCTGTGGCCTGGAT
GTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACTGGGCTCTGATCATCCCTCAGAGGTG
CCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCATTCACTACAAGGGAACGAGGACTTAC
AACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCACCCGTTCTCCCCGGCACCCGGGAGTC
ATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGAATCTTTCAAAAGTGAACACACTGTT
TTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTATAATGGATTTCCAGTTCTTAGGAAC
AATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAGTAGTCCTAATAGCCCTTTGCCCATG
TTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCCTCAGATGTGGTCTAGGTGTCTACTG
CGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGTCAGGGCTCTGAAAACAGCATATGAT
GTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTATGCAACTCTGTGGACAATATGATCAG
CCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTACTTATGGTTATTATAATAAGGCTGTT
TTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGTTGTTTTAGGAGTAACACAGTTCAAA
AGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGGTGGCCAGTCTGATCTTGGATATAATTCATTATCTAAAGATGAA
GTTAGAAGAGGGGATACATCTACTGAAGACATTCAAGAAGAAAAAGATAAAAAAGGGAGTGATTGTAGTTCCTTGTCAGAGAGTGAGAGT
ACAAAAGGAAGTGCTGATTGCCTTCCTAAGCTCAGTTATCAAAATTCTTCCAGTATCGTTCGCCTCACTGGTACAAGTAACAACAGTGCT
GGTAAAATATCAGGAGAAAGCATGGAAAGCACACCTGAGCTGCTCTTAATATCATCTCTTGAAGATACAAATGAAACACGAAACATTCAA
AGTAGATGCTTCAGGAAAAGACATAAAAGTGACAATGAAACTAATTTGCAGCAGCAAGTGGTCTGGGGAAATAGAAACCGTAATCTTAGT
GGAGGGGTACTGATGGGATTTATGCTCAATAGAATTAACCAGGAAGCAACCCCTGGAGATATAGTTGAAAAATTGGGAGCTGATGCAAAA
ATTCTTTCAAATGTTATCTCAAAAAGCACGAGACCAAATACTCTTGATATTGGGAAGCCACCTTTAAGATCAAAAAGAGACAGTCTAGAA
AAGGAATCTAGTGATGATGATACACCTTTTGATGGTTCTAACTATTTGGCAGATAAAGTGGATTCTCCTGTTATTTTTGACTTAGAAGAC
TTAGACAGTGAAACAGATGTATCAAAAGCAGGATGTGTTGCTACACAAAATCCCAAGAGGATTCAACGTATGAACAGCAGCTTTTCAGTA
AAACCTTTTGAAAAAACTGATGTCGCAACAGGATTTGATCCCCTCTCTCTTTTGGTTGCTGAGACTGAACAGCAGCAAAAAGAAGAAGAG
GAGGAGGATGAAGATGATAGCAAAAGCATTTCAACACCATCTGCTAGGCGTGATTTAGCTGAAGAAATTGTGATGTATATGAATAACATG
AGCAGTCCTTTGACAAGTCGTACACCAAGCATTGATTTACAACGGGCATGTGATGATAAATTAAATAAGAAAAGTCCACCATTGGTCAAG
GCATGCAGAAGATCTAGTCTGCCTCCTAATTCTCCTAAGCCAGTGAGACTTACCAAATCTAAAAGTTACACAAAAAGTGAGGAGAAACCA
AGGGATAGACTTTGGTCTTCTCCAGCCTTCTCACCTACTTGCCCATTTAGGGAAGAATCTCAGGATACATTAACCCACTCATCACCTTCA
TTTAACTTAGATACACTACTAGTACCTAAACTAGATGTTCTAAGAAACAGTATGTTCACTGCTGGAAAAGGAGTTGCAGAGAAAGCAAGC
AAATGGTATTCAAGATTCACCATGTACACCACATCATCTAAGGATCAAAGTTCTGATCGTACCAGTCTTTCTTCAGTGGGAGCCCAGGAT
TCTGAATCTACCTCTTTAACAGATGAAGATGTCTGCCATGAGTTGGAAGGACCTATCTCCTCTCAAGAGACCAGTGCTACTTCAGGGACT
AAGAGAATTGATCTCAGCCGAATAAGCCTGGAAAGTTCTGCATCCTTGGAAGGATCTCTGTCGAAGTTTGCCTTACCTGGGAAATCAGAA
GTGACATCTTCCTTCAACGCGAGTAATACAAATATCTTCCAGAACTATGCAATGGAGGTTCTCATCTCAAGTTGCTCTCGGTGTAGAACT
TGTGATTGTCTTGTCCATGATGAGGAAATCATGGCTGGCTGGACAGCAGATGATTCAAATCTCAATACTACATGCCCATTCTGTGGCAAT
ATCTTCTTACCCTTTCTGAATATAGAAATAAGAGATTTAAGACGACCTGGAAGATACTTTCTAAAGTCAAGCCCATCAACAGAAAATATG
CACTTTCCATCCTCCATTTCAAGTCAGACGAGGCAGTCTTGCATTTCAACATCAGCCTCTGGTCTTGACACATCTGCTCTCTCTGTTCAA
GGGAATTTTGATCTAAATAGCAAATCTAAACTGCAGGAAAATTTTTGCACCCGAAGTATTCAGATCCCTGCTAATAGATCAAAAACAGCT
ATGTCTAAATGTCCAATATTTCCAATGGCCAGGAGTATTAGTACTTCTGGCCCCTTGGATAAGGAAGATACTGGAAGACAGAAGCTCATT
TCTACAGGCAGCCTGCCAGCTACTTTACAAGGAGCTACAGATTCTTTAGGTTTAGAATGGCACCTTCCAAGTCCCGATCCTGTCACTGTT
CCGTATCTTAGTCCTTTAGTGGTATGGAAAGAACTTGAAAGCTTATTGGAAAATGAAGGTGATCATGCAATAACAGTAGCAGACTTTGTG
GACCATCATCCAATTGTTTTTTGGAACCTGGTATGGTATTTCAGACGTCTTGACTTGCCCAGTAACTTACCTGGATTGATTCTTTCTTCT
GAGCACTGTAACAAGTATTCAAAGATTCCCCGCCACTGTATGTCTGAAGATAGCAAATATGTTTTAATACAAATGTTATGGGACAATATG
AAGTTACATCAGGATCCGGGACAGCCCTTGTACATTCTCTGGAATGCACACACCCAAAAATATCCAATGGTCCATTTATTGCAAAAAAGT
GATAACTCATTTAACCAGGAACTGTTGAAAAGTATGGTAAAAAGCATTAAAATGAATGATGTCTATGGACCAATGAGTCAGATTTTAGAG
ACACTGAATAAGTGTCCACATTTTAAAAGACAGAGGAGTTTATACAGAGAAATACTATTTCTCTCACTTGTGGCACTGGGAAGAGAAAAC
ATTGATATAGATGCTTTTGATAAAGAGTACAAGATGGCATACGATCGTCTCACACCTAGTCAAGTCAAGAGTACACACAACTGTGATAGA
CCACCAAGTACAGGGGTGATGGAATGTCGAAAAACCTTTGGAGAACCTTATCTTTAAGATGTATTTGTATGTGTAAACATTCAATGTATA

>101159_101159_3_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000553891_DENND4A_chr15_65998562_ENST00000431932_length(amino acids)=1613AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGT
SNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDNETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKL
GADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDGSNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMN
SSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSISTPSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKS
PPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSPTCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGV
AEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFAL
PGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSP
STENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTG
RQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPG
LILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPM

--------------------------------------------------------------
>101159_101159_4_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000553891_DENND4A_chr15_65998562_ENST00000443035_length(transcript)=6821nt_BP=1818nt
ACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGAGGGTGGCGGAGATGGAGATGAGGAT
GGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCGCCTTGCTGCGGCCGAGCTTCTCAGT
GGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCATTACCAAAACTTTGTAGCTGATGTC
CAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCCAAGTCAATTTTGACCACATCTTTGC
TTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAGAGGCAGCAAATTAAAAATTTGAACA
TTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGTGGAAGTTTCGTGCAGTCTTCAGACT
CAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTACCAGCGTGAGTATGAGTGCCCAGACT
TCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGACTGATGAAGCTATCTTTGAGTGTGAT
GAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAACCATGAGCGGATAAGACTCAAACCT
GGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAGGGCAATAGTGAGGTGCCAGACCTGC
AAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCCTGTTACTGTGTACAATGTCAGTAAT
CTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAAGGTTGTGAGTTTCCTCCTAGTAGAC
GAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGATCAGCATCTGAAAGTGGTTTCCATT
TTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGTCTTTAAAACCTCCCCGACCCAGGAG
TCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGAAGGGCTCCTGGGGGCCACCGTGAAT
CTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAACTCATGCAGACCGGCTGCATAACGAC
CTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGCCACCACTGCTCGCTGTGGCCTGGAT
GTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACTGGGCTCTGATCATCCCTCAGAGGTG
CCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCATTCACTACAAGGGAACGAGGACTTAC
AACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCACCCGTTCTCCCCGGCACCCGGGAGTC
ATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGAATCTTTCAAAAGTGAACACACTGTT
TTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTATAATGGATTTCCAGTTCTTAGGAAC
AATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAGTAGTCCTAATAGCCCTTTGCCCATG
TTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCCTCAGATGTGGTCTAGGTGTCTACTG
CGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGTCAGGGCTCTGAAAACAGCATATGAT
GTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTATGCAACTCTGTGGACAATATGATCAG
CCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTACTTATGGTTATTATAATAAGGCTGTT
TTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGTTGTTTTAGGAGTAACACAGTTCAAA
AGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGATGGCAGTGACCTGGATGCTGTTAGTCATGGCAGCATGGATAGT
GGTCATGGGACACACACTGTGGAGCAGGCACCTTTTAATACGGGTTTAATCAAAGTATATGCTACTGATGATAGATCTAGTACAGGTGGC
CAGTCTGATCTTGGATATAATTCATTATCTAAAGATGAAGTTAGAAGAGGGGATACATCTACTGAAGACATTCAAGAAGAAAAAGATAAA
AAAGGGAGTGATTGTAGTTCCTTGTCAGAGAGTGAGAGTACAAAAGGAAGTGCTGATTGCCTTCCTAAGCTCAGTTATCAAAATTCTTCC
AGTATCGTTCGCCTCACTGGTACAAGTAACAACAGTGCTGGTAAAATATCAGGAGAAAGCATGGAAAGCACACCTGAGCTGCTCTTAATA
TCATCTCTTGAAGATACAAATGAAACACGAAACATTCAAAGTAGATGCTTCAGGAAAAGACATAAAAGTGACAATGAAACTAATTTGCAG
CAGCAAGTGGTCTGGGGAAATAGAAACCGTAATCTTAGTGGAGGGGTACTGATGGGATTTATGCTCAATAGAATTAACCAGGAAGCAACC
CCTGGAGATATAGTTGAAAAATTGGGAGCTGATGCAAAAATTCTTTCAAATGTTATCTCAAAAAGCACGAGACCAAATACTCTTGATATT
GGGAAGCCACCTTTAAGATCAAAAAGAGACAGTCTAGAAAAGGAATCTAGTGATGATGATACACCTTTTGATGGTTCTAACTATTTGGCA
GATAAAGTGGATTCTCCTGTTATTTTTGACTTAGAAGACTTAGACAGTGAAACAGATGTATCAAAAGCAGGATGTGTTGCTACACAAAAT
CCCAAGAGGATTCAACGTATGAACAGCAGCTTTTCAGTAAAACCTTTTGAAAAAACTGATGTCGCAACAGGATTTGATCCCCTCTCTCTT
TTGGTTGCTGAGACTGAACAGCAGCAAAAAGAAGAAGAGGAGGAGGATGAAGATGATAGCAAAAGCATTTCAACACCATCTGCTAGGCGT
GATTTAGCTGAAGAAATTGTGATGTATATGAATAACATGAGCAGTCCTTTGACAAGTCGTACACCAAGCATTGATTTACAACGGGCATGT
GATGATAAATTAAATAAGAAAAGTCCACCATTGGTCAAGGCATGCAGAAGATCTAGTCTGCCTCCTAATTCTCCTAAGCCAGTGAGACTT
ACCAAATCTAAAAGTTACACAAAAAGTGAGGAGAAACCAAGGGATAGACTTTGGTCTTCTCCAGCCTTCTCACCTACTTGCCCATTTAGG
GAAGAATCTCAGGATACATTAACCCACTCATCACCTTCATTTAACTTAGATACACTACTAGTACCTAAACTAGATGTTCTAAGAAACAGT
ATGTTCACTGCTGGAAAAGGAGTTGCAGAGAAAGCAAGCAAATGGTATTCAAGATTCACCATGTACACCACATCATCTAAGGATCAAAGT
TCTGATCGTACCAGTCTTTCTTCAGTGGGAGCCCAGGATTCTGAATCTACCTCTTTAACAGATGAAGATGTCTGCCATGAGTTGGAAGGA
CCTATCTCCTCTCAAGAGACCAGTGCTACTTCAGGGACTAAGAGAATTGATCTCAGCCGAATAAGCCTGGAAAGTTCTGCATCCTTGGAA
GGATCTCTGTCGAAGTTTGCCTTACCTGGGAAATCAGAAGTGACATCTTCCTTCAACGCGAGTAATACAAATATCTTCCAGAACTATGCA
ATGGAGGTTCTCATCTCAAGTTGCTCTCGGTGTAGAACTTGTGATTGTCTTGTCCATGATGAGGAAATCATGGCTGGCTGGACAGCAGAT
GATTCAAATCTCAATACTACATGCCCATTCTGTGGCAATATCTTCTTACCCTTTCTGAATATAGAAATAAGAGATTTAAGACGACCTGGA
AGATACTTTCTAAAGTCAAGCCCATCAACAGAAAATATGCACTTTCCATCCTCCATTTCAAGTCAGACGAGGCAGTCTTGCATTTCAACA
TCAGCCTCTGGTCTTGACACATCTGCTCTCTCTGTTCAAGGGAATTTTGATCTAAATAGCAAATCTAAACTGCAGGAAAATTTTTGCACC
CGAAGTATTCAGATCCCTGCTAATAGATCAAAAACAGCTATGTCTAAATGTCCAATATTTCCAATGGCCAGGAGTATTAGTACTTCTGGC
CCCTTGGATAAGGAAGATACTGGAAGACAGAAGCTCATTTCTACAGGCAGCCTGCCAGCTACTTTACAAGGAGCTACAGATTCTTTAGGT
TTAGAATGGCACCTTCCAAGTCCCGATCCTGTCACTGTTCCGTATCTTAGTCCTTTAGTGGTATGGAAAGAACTTGAAAGCTTATTGGAA
AATGAAGGTGATCATGCAATAACAGTAGCAGACTTTGTGGACCATCATCCAATTGTTTTTTGGAACCTGGTATGGTATTTCAGACGTCTT
GACTTGCCCAGTAACTTACCTGGATTGATTCTTTCTTCTGAGCACTGTAACAAGTATTCAAAGATTCCCCGCCACTGTATGTCTGAAGAT
AGCAAATATGTTTTAATACAAATGTTATGGGACAATATGAAGTTACATCAGGATCCGGGACAGCCCTTGTACATTCTCTGGAATGCACAC
ACCCAAAAATATCCAATGGTCCATTTATTGCAAAAAAGTGATAACTCATTTAACCAGGAACTGTTGAAAAGTATGGTAAAAAGCATTAAA
ATGAATGATGTCTATGGACCAATGAGTCAGATTTTAGAGACACTGAATAAGTGTCCACATTTTAAAAGACAGAGGAGTTTATACAGAGAA
ATACTATTTCTCTCACTTGTGGCACTGGGAAGAGAAAACATTGATATAGATGCTTTTGATAAAGAGTACAAGATGGCATACGATCGTCTC
ACACCTAGTCAAGTCAAGAGTACACACAACTGTGATAGACCACCAAGTACAGGGGTGATGGAATGTCGAAAAACCTTTGGAGAACCTTAT
CTTTAAGATGTATTTGTATGTGTAAACATTCAATGTATATTGTATAGTCAGTGTATAAAATAACACTTTTAGACTCTAAATATTTTTTCT
TCAATTTTTGAAAATACAATTTGTAAATGGTTCAAAAGACTCAGACAGCTTATGTACAGAATGTTTGAAGAAGAGAATAGTGACAAGTGG
GGAGAAAGCCACTTTGTTTCTCATTTCTTTTTTCTTCTTCTTTAACTCCCCTGTAATAGGAAATAAAGTATTTTTGTGATGAGGAAATCC
CTAAACAAAATTAGTTGCCATAAAATATGACAACTGCTTTATGGTTTCTTTTGGAAGAGACAGATTGAAAAATCATGAATGGAATCTAAA
CAGAAATGTCAGATGAACGTATTTCCTGTTTTCATAGACTATTCAAATGTTTTGACCATGAAGTTGTATTATACATATTTTAAATTGTTT
ATAGTAAGTTGATATTTTTTTAATTTTTAAATTTAATATAGCAAACTTAAAATGAATTTAAACTTAAGCAAGCAAGCGTGTATTTTCCTT
GTCTGCTGCTATTTGAAGTAATTAGTACAGCTGCAGATCTCTCTGTGTATATCTATCTATATATATATTTTTTATTACTTGGGAGAATGA
ATTTTAAAATGTCAGTGCTAGTGTCAAGTGTTGTCCTAGGATTGCATGTTAGTACCCCTAAGCCTGAGTGTGGGGAGTGAGTTATGCAAG
GGTAGCGTGCACTGCCCAGACTGACTCATGGAGCCTTGTGCAAGGAGAGCCAGAGAGGTTCACTATACCATGACTCCAAAATTGTCTCTA
TTGCTAATAGATACGTATAGTATACAGGGAAAACAGCTTATAAATCCAAATATCAATTTAAATTTTAATATTCTACATGAAAACTTACAT
TGGGAAATATGCAGACAAGTGATTATATTCCAAATTTTACCCTTATTTTAATATCTAAAATATTGGGTATGATGCAAATTATACTATAGA
ATATTTATCTGAAATATGACTTACTGGGGTATTCTGTTAATACTATATATAAATATTCAGAATTTTTTTCAAAAGTAGAAAAATTCCCCT
CTAAAAGTACAGCCAGATAGATTTTCATCCATATTGAGGAACTTAGCTTTTTCAACAAGCTTCAGAATCTGAAGTCTGTAGAATCTAAAA

>101159_101159_4_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000553891_DENND4A_chr15_65998562_ENST00000443035_length(amino acids)=1656AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSDGSDLDAVSHGSMDSGHGTHTVEQAPFNTGLIKVYATDDRSSTGGQSDLGYNSLSKDEVRRGDTSTEDIQ
EEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGTSNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDN
ETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKLGADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDG
SNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMNSSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSIST
PSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKSPPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSP
TCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVC
HELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFALPGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMA
GWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQ
ENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKEL
ESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYI
LWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKM

--------------------------------------------------------------
>101159_101159_5_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000556143_DENND4A_chr15_65998562_ENST00000431932_length(transcript)=5637nt_BP=1924nt
AGTGCGCACTACGCCCTTGCTGGCGCCGGGATCCTCCCTCTCTCGCTCCTCCCTTTCTGGGCTGCACCGCTCACGCCTTCCTGTTAGTCC
GAGCTGGGAGAAGTTCACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGAGGGTGGCGG
AGATGGAGATGAGGATGGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCGCCTTGCTGC
GGCCGAGCTTCTCAGTGGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCATTACCAAAA
CTTTGTAGCTGATGTCCAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCCAAGTCAATT
TTGACCACATCTTTGCTTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAGAGGCAGCAA
ATTAAAAATTTGAACATTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGTGGAAGTTTC
GTGCAGTCTTCAGACTCAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTACCAGCGTGAG
TATGAGTGCCCAGACTTCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGACTGATGAAGC
TATCTTTGAGTGTGATGAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAACCATGAGCG
GATAAGACTCAAACCTGGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAGGGCAATAGT
GAGGTGCCAGACCTGCAAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCCTGTTACTGT
GTACAATGTCAGTAATCTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAAGGTTGTGAG
TTTCCTCCTAGTAGACGAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGATCAGCATCT
GAAAGTGGTTTCCATTTTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGTCTTTAAAAC
CTCCCCGACCCAGGAGTCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGAAGGGCTCCT
GGGGGCCACCGTGAATCTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAACTCATGCAGA
CCGGCTGCATAACGACCTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGCCACCACTGC
TCGCTGTGGCCTGGATGTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACTGGGCTCTGA
TCATCCCTCAGAGGTGCCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCATTCACTACAA
GGGAACGAGGACTTACAACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCACCCGTTCTCC
CCGGCACCCGGGAGTCATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGAATCTTTCAA
AAGTGAACACACTGTTTTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTATAATGGATT
TCCAGTTCTTAGGAACAATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAGTAGTCCTAA
TAGCCCTTTGCCCATGTTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCCTCAGATGTG
GTCTAGGTGTCTACTGCGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGTCAGGGCTCT
GAAAACAGCATATGATGTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTATGCAACTCTG
TGGACAATATGATCAGCCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTACTTATGGTTA
TTATAATAAGGCTGTTTTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGTTGTTTTAGG
AGTAACACAGTTCAAAAGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGGTGGCCAGTCTGATCTTGGATATAATTC
ATTATCTAAAGATGAAGTTAGAAGAGGGGATACATCTACTGAAGACATTCAAGAAGAAAAAGATAAAAAAGGGAGTGATTGTAGTTCCTT
GTCAGAGAGTGAGAGTACAAAAGGAAGTGCTGATTGCCTTCCTAAGCTCAGTTATCAAAATTCTTCCAGTATCGTTCGCCTCACTGGTAC
AAGTAACAACAGTGCTGGTAAAATATCAGGAGAAAGCATGGAAAGCACACCTGAGCTGCTCTTAATATCATCTCTTGAAGATACAAATGA
AACACGAAACATTCAAAGTAGATGCTTCAGGAAAAGACATAAAAGTGACAATGAAACTAATTTGCAGCAGCAAGTGGTCTGGGGAAATAG
AAACCGTAATCTTAGTGGAGGGGTACTGATGGGATTTATGCTCAATAGAATTAACCAGGAAGCAACCCCTGGAGATATAGTTGAAAAATT
GGGAGCTGATGCAAAAATTCTTTCAAATGTTATCTCAAAAAGCACGAGACCAAATACTCTTGATATTGGGAAGCCACCTTTAAGATCAAA
AAGAGACAGTCTAGAAAAGGAATCTAGTGATGATGATACACCTTTTGATGGTTCTAACTATTTGGCAGATAAAGTGGATTCTCCTGTTAT
TTTTGACTTAGAAGACTTAGACAGTGAAACAGATGTATCAAAAGCAGGATGTGTTGCTACACAAAATCCCAAGAGGATTCAACGTATGAA
CAGCAGCTTTTCAGTAAAACCTTTTGAAAAAACTGATGTCGCAACAGGATTTGATCCCCTCTCTCTTTTGGTTGCTGAGACTGAACAGCA
GCAAAAAGAAGAAGAGGAGGAGGATGAAGATGATAGCAAAAGCATTTCAACACCATCTGCTAGGCGTGATTTAGCTGAAGAAATTGTGAT
GTATATGAATAACATGAGCAGTCCTTTGACAAGTCGTACACCAAGCATTGATTTACAACGGGCATGTGATGATAAATTAAATAAGAAAAG
TCCACCATTGGTCAAGGCATGCAGAAGATCTAGTCTGCCTCCTAATTCTCCTAAGCCAGTGAGACTTACCAAATCTAAAAGTTACACAAA
AAGTGAGGAGAAACCAAGGGATAGACTTTGGTCTTCTCCAGCCTTCTCACCTACTTGCCCATTTAGGGAAGAATCTCAGGATACATTAAC
CCACTCATCACCTTCATTTAACTTAGATACACTACTAGTACCTAAACTAGATGTTCTAAGAAACAGTATGTTCACTGCTGGAAAAGGAGT
TGCAGAGAAAGCAAGCAAATGGTATTCAAGATTCACCATGTACACCACATCATCTAAGGATCAAAGTTCTGATCGTACCAGTCTTTCTTC
AGTGGGAGCCCAGGATTCTGAATCTACCTCTTTAACAGATGAAGATGTCTGCCATGAGTTGGAAGGACCTATCTCCTCTCAAGAGACCAG
TGCTACTTCAGGGACTAAGAGAATTGATCTCAGCCGAATAAGCCTGGAAAGTTCTGCATCCTTGGAAGGATCTCTGTCGAAGTTTGCCTT
ACCTGGGAAATCAGAAGTGACATCTTCCTTCAACGCGAGTAATACAAATATCTTCCAGAACTATGCAATGGAGGTTCTCATCTCAAGTTG
CTCTCGGTGTAGAACTTGTGATTGTCTTGTCCATGATGAGGAAATCATGGCTGGCTGGACAGCAGATGATTCAAATCTCAATACTACATG
CCCATTCTGTGGCAATATCTTCTTACCCTTTCTGAATATAGAAATAAGAGATTTAAGACGACCTGGAAGATACTTTCTAAAGTCAAGCCC
ATCAACAGAAAATATGCACTTTCCATCCTCCATTTCAAGTCAGACGAGGCAGTCTTGCATTTCAACATCAGCCTCTGGTCTTGACACATC
TGCTCTCTCTGTTCAAGGGAATTTTGATCTAAATAGCAAATCTAAACTGCAGGAAAATTTTTGCACCCGAAGTATTCAGATCCCTGCTAA
TAGATCAAAAACAGCTATGTCTAAATGTCCAATATTTCCAATGGCCAGGAGTATTAGTACTTCTGGCCCCTTGGATAAGGAAGATACTGG
AAGACAGAAGCTCATTTCTACAGGCAGCCTGCCAGCTACTTTACAAGGAGCTACAGATTCTTTAGGTTTAGAATGGCACCTTCCAAGTCC
CGATCCTGTCACTGTTCCGTATCTTAGTCCTTTAGTGGTATGGAAAGAACTTGAAAGCTTATTGGAAAATGAAGGTGATCATGCAATAAC
AGTAGCAGACTTTGTGGACCATCATCCAATTGTTTTTTGGAACCTGGTATGGTATTTCAGACGTCTTGACTTGCCCAGTAACTTACCTGG
ATTGATTCTTTCTTCTGAGCACTGTAACAAGTATTCAAAGATTCCCCGCCACTGTATGTCTGAAGATAGCAAATATGTTTTAATACAAAT
GTTATGGGACAATATGAAGTTACATCAGGATCCGGGACAGCCCTTGTACATTCTCTGGAATGCACACACCCAAAAATATCCAATGGTCCA
TTTATTGCAAAAAAGTGATAACTCATTTAACCAGGAACTGTTGAAAAGTATGGTAAAAAGCATTAAAATGAATGATGTCTATGGACCAAT
GAGTCAGATTTTAGAGACACTGAATAAGTGTCCACATTTTAAAAGACAGAGGAGTTTATACAGAGAAATACTATTTCTCTCACTTGTGGC
ACTGGGAAGAGAAAACATTGATATAGATGCTTTTGATAAAGAGTACAAGATGGCATACGATCGTCTCACACCTAGTCAAGTCAAGAGTAC
ACACAACTGTGATAGACCACCAAGTACAGGGGTGATGGAATGTCGAAAAACCTTTGGAGAACCTTATCTTTAAGATGTATTTGTATGTGT

>101159_101159_5_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000556143_DENND4A_chr15_65998562_ENST00000431932_length(amino acids)=1613AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGT
SNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDNETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKL
GADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDGSNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMN
SSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSISTPSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKS
PPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSPTCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGV
AEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFAL
PGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSP
STENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTG
RQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPG
LILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPM

--------------------------------------------------------------
>101159_101159_6_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000556143_DENND4A_chr15_65998562_ENST00000443035_length(transcript)=6927nt_BP=1924nt
AGTGCGCACTACGCCCTTGCTGGCGCCGGGATCCTCCCTCTCTCGCTCCTCCCTTTCTGGGCTGCACCGCTCACGCCTTCCTGTTAGTCC
GAGCTGGGAGAAGTTCACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGAGGGTGGCGG
AGATGGAGATGAGGATGGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCGCCTTGCTGC
GGCCGAGCTTCTCAGTGGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCATTACCAAAA
CTTTGTAGCTGATGTCCAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCCAAGTCAATT
TTGACCACATCTTTGCTTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAGAGGCAGCAA
ATTAAAAATTTGAACATTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGTGGAAGTTTC
GTGCAGTCTTCAGACTCAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTACCAGCGTGAG
TATGAGTGCCCAGACTTCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGACTGATGAAGC
TATCTTTGAGTGTGATGAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAACCATGAGCG
GATAAGACTCAAACCTGGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAGGGCAATAGT
GAGGTGCCAGACCTGCAAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCCTGTTACTGT
GTACAATGTCAGTAATCTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAAGGTTGTGAG
TTTCCTCCTAGTAGACGAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGATCAGCATCT
GAAAGTGGTTTCCATTTTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGTCTTTAAAAC
CTCCCCGACCCAGGAGTCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGAAGGGCTCCT
GGGGGCCACCGTGAATCTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAACTCATGCAGA
CCGGCTGCATAACGACCTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGCCACCACTGC
TCGCTGTGGCCTGGATGTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACTGGGCTCTGA
TCATCCCTCAGAGGTGCCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCATTCACTACAA
GGGAACGAGGACTTACAACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCACCCGTTCTCC
CCGGCACCCGGGAGTCATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGAATCTTTCAA
AAGTGAACACACTGTTTTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTATAATGGATT
TCCAGTTCTTAGGAACAATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAGTAGTCCTAA
TAGCCCTTTGCCCATGTTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCCTCAGATGTG
GTCTAGGTGTCTACTGCGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGTCAGGGCTCT
GAAAACAGCATATGATGTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTATGCAACTCTG
TGGACAATATGATCAGCCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTACTTATGGTTA
TTATAATAAGGCTGTTTTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGTTGTTTTAGG
AGTAACACAGTTCAAAAGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGATGGCAGTGACCTGGATGCTGTTAGTCA
TGGCAGCATGGATAGTGGTCATGGGACACACACTGTGGAGCAGGCACCTTTTAATACGGGTTTAATCAAAGTATATGCTACTGATGATAG
ATCTAGTACAGGTGGCCAGTCTGATCTTGGATATAATTCATTATCTAAAGATGAAGTTAGAAGAGGGGATACATCTACTGAAGACATTCA
AGAAGAAAAAGATAAAAAAGGGAGTGATTGTAGTTCCTTGTCAGAGAGTGAGAGTACAAAAGGAAGTGCTGATTGCCTTCCTAAGCTCAG
TTATCAAAATTCTTCCAGTATCGTTCGCCTCACTGGTACAAGTAACAACAGTGCTGGTAAAATATCAGGAGAAAGCATGGAAAGCACACC
TGAGCTGCTCTTAATATCATCTCTTGAAGATACAAATGAAACACGAAACATTCAAAGTAGATGCTTCAGGAAAAGACATAAAAGTGACAA
TGAAACTAATTTGCAGCAGCAAGTGGTCTGGGGAAATAGAAACCGTAATCTTAGTGGAGGGGTACTGATGGGATTTATGCTCAATAGAAT
TAACCAGGAAGCAACCCCTGGAGATATAGTTGAAAAATTGGGAGCTGATGCAAAAATTCTTTCAAATGTTATCTCAAAAAGCACGAGACC
AAATACTCTTGATATTGGGAAGCCACCTTTAAGATCAAAAAGAGACAGTCTAGAAAAGGAATCTAGTGATGATGATACACCTTTTGATGG
TTCTAACTATTTGGCAGATAAAGTGGATTCTCCTGTTATTTTTGACTTAGAAGACTTAGACAGTGAAACAGATGTATCAAAAGCAGGATG
TGTTGCTACACAAAATCCCAAGAGGATTCAACGTATGAACAGCAGCTTTTCAGTAAAACCTTTTGAAAAAACTGATGTCGCAACAGGATT
TGATCCCCTCTCTCTTTTGGTTGCTGAGACTGAACAGCAGCAAAAAGAAGAAGAGGAGGAGGATGAAGATGATAGCAAAAGCATTTCAAC
ACCATCTGCTAGGCGTGATTTAGCTGAAGAAATTGTGATGTATATGAATAACATGAGCAGTCCTTTGACAAGTCGTACACCAAGCATTGA
TTTACAACGGGCATGTGATGATAAATTAAATAAGAAAAGTCCACCATTGGTCAAGGCATGCAGAAGATCTAGTCTGCCTCCTAATTCTCC
TAAGCCAGTGAGACTTACCAAATCTAAAAGTTACACAAAAAGTGAGGAGAAACCAAGGGATAGACTTTGGTCTTCTCCAGCCTTCTCACC
TACTTGCCCATTTAGGGAAGAATCTCAGGATACATTAACCCACTCATCACCTTCATTTAACTTAGATACACTACTAGTACCTAAACTAGA
TGTTCTAAGAAACAGTATGTTCACTGCTGGAAAAGGAGTTGCAGAGAAAGCAAGCAAATGGTATTCAAGATTCACCATGTACACCACATC
ATCTAAGGATCAAAGTTCTGATCGTACCAGTCTTTCTTCAGTGGGAGCCCAGGATTCTGAATCTACCTCTTTAACAGATGAAGATGTCTG
CCATGAGTTGGAAGGACCTATCTCCTCTCAAGAGACCAGTGCTACTTCAGGGACTAAGAGAATTGATCTCAGCCGAATAAGCCTGGAAAG
TTCTGCATCCTTGGAAGGATCTCTGTCGAAGTTTGCCTTACCTGGGAAATCAGAAGTGACATCTTCCTTCAACGCGAGTAATACAAATAT
CTTCCAGAACTATGCAATGGAGGTTCTCATCTCAAGTTGCTCTCGGTGTAGAACTTGTGATTGTCTTGTCCATGATGAGGAAATCATGGC
TGGCTGGACAGCAGATGATTCAAATCTCAATACTACATGCCCATTCTGTGGCAATATCTTCTTACCCTTTCTGAATATAGAAATAAGAGA
TTTAAGACGACCTGGAAGATACTTTCTAAAGTCAAGCCCATCAACAGAAAATATGCACTTTCCATCCTCCATTTCAAGTCAGACGAGGCA
GTCTTGCATTTCAACATCAGCCTCTGGTCTTGACACATCTGCTCTCTCTGTTCAAGGGAATTTTGATCTAAATAGCAAATCTAAACTGCA
GGAAAATTTTTGCACCCGAAGTATTCAGATCCCTGCTAATAGATCAAAAACAGCTATGTCTAAATGTCCAATATTTCCAATGGCCAGGAG
TATTAGTACTTCTGGCCCCTTGGATAAGGAAGATACTGGAAGACAGAAGCTCATTTCTACAGGCAGCCTGCCAGCTACTTTACAAGGAGC
TACAGATTCTTTAGGTTTAGAATGGCACCTTCCAAGTCCCGATCCTGTCACTGTTCCGTATCTTAGTCCTTTAGTGGTATGGAAAGAACT
TGAAAGCTTATTGGAAAATGAAGGTGATCATGCAATAACAGTAGCAGACTTTGTGGACCATCATCCAATTGTTTTTTGGAACCTGGTATG
GTATTTCAGACGTCTTGACTTGCCCAGTAACTTACCTGGATTGATTCTTTCTTCTGAGCACTGTAACAAGTATTCAAAGATTCCCCGCCA
CTGTATGTCTGAAGATAGCAAATATGTTTTAATACAAATGTTATGGGACAATATGAAGTTACATCAGGATCCGGGACAGCCCTTGTACAT
TCTCTGGAATGCACACACCCAAAAATATCCAATGGTCCATTTATTGCAAAAAAGTGATAACTCATTTAACCAGGAACTGTTGAAAAGTAT
GGTAAAAAGCATTAAAATGAATGATGTCTATGGACCAATGAGTCAGATTTTAGAGACACTGAATAAGTGTCCACATTTTAAAAGACAGAG
GAGTTTATACAGAGAAATACTATTTCTCTCACTTGTGGCACTGGGAAGAGAAAACATTGATATAGATGCTTTTGATAAAGAGTACAAGAT
GGCATACGATCGTCTCACACCTAGTCAAGTCAAGAGTACACACAACTGTGATAGACCACCAAGTACAGGGGTGATGGAATGTCGAAAAAC
CTTTGGAGAACCTTATCTTTAAGATGTATTTGTATGTGTAAACATTCAATGTATATTGTATAGTCAGTGTATAAAATAACACTTTTAGAC
TCTAAATATTTTTTCTTCAATTTTTGAAAATACAATTTGTAAATGGTTCAAAAGACTCAGACAGCTTATGTACAGAATGTTTGAAGAAGA
GAATAGTGACAAGTGGGGAGAAAGCCACTTTGTTTCTCATTTCTTTTTTCTTCTTCTTTAACTCCCCTGTAATAGGAAATAAAGTATTTT
TGTGATGAGGAAATCCCTAAACAAAATTAGTTGCCATAAAATATGACAACTGCTTTATGGTTTCTTTTGGAAGAGACAGATTGAAAAATC
ATGAATGGAATCTAAACAGAAATGTCAGATGAACGTATTTCCTGTTTTCATAGACTATTCAAATGTTTTGACCATGAAGTTGTATTATAC
ATATTTTAAATTGTTTATAGTAAGTTGATATTTTTTTAATTTTTAAATTTAATATAGCAAACTTAAAATGAATTTAAACTTAAGCAAGCA
AGCGTGTATTTTCCTTGTCTGCTGCTATTTGAAGTAATTAGTACAGCTGCAGATCTCTCTGTGTATATCTATCTATATATATATTTTTTA
TTACTTGGGAGAATGAATTTTAAAATGTCAGTGCTAGTGTCAAGTGTTGTCCTAGGATTGCATGTTAGTACCCCTAAGCCTGAGTGTGGG
GAGTGAGTTATGCAAGGGTAGCGTGCACTGCCCAGACTGACTCATGGAGCCTTGTGCAAGGAGAGCCAGAGAGGTTCACTATACCATGAC
TCCAAAATTGTCTCTATTGCTAATAGATACGTATAGTATACAGGGAAAACAGCTTATAAATCCAAATATCAATTTAAATTTTAATATTCT
ACATGAAAACTTACATTGGGAAATATGCAGACAAGTGATTATATTCCAAATTTTACCCTTATTTTAATATCTAAAATATTGGGTATGATG
CAAATTATACTATAGAATATTTATCTGAAATATGACTTACTGGGGTATTCTGTTAATACTATATATAAATATTCAGAATTTTTTTCAAAA
GTAGAAAAATTCCCCTCTAAAAGTACAGCCAGATAGATTTTCATCCATATTGAGGAACTTAGCTTTTTCAACAAGCTTCAGAATCTGAAG

>101159_101159_6_ZFYVE1-DENND4A_ZFYVE1_chr14_73459850_ENST00000556143_DENND4A_chr15_65998562_ENST00000443035_length(amino acids)=1656AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSDGSDLDAVSHGSMDSGHGTHTVEQAPFNTGLIKVYATDDRSSTGGQSDLGYNSLSKDEVRRGDTSTEDIQ
EEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGTSNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDN
ETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKLGADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDG
SNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMNSSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSIST
PSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKSPPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSP
TCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVC
HELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFALPGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMA
GWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQ
ENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKEL
ESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYI
LWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKM

--------------------------------------------------------------
>101159_101159_7_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000318876_DENND4A_chr15_65998562_ENST00000431932_length(transcript)=5556nt_BP=1843nt
TGTTAGTCCGAGCTGGGAGAAGTTCACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGA
GGGTGGCGGAGATGGAGATGAGGATGGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCG
CCTTGCTGCGGCCGAGCTTCTCAGTGGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCA
TTACCAAAACTTTGTAGCTGATGTCCAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCC
AAGTCAATTTTGACCACATCTTTGCTTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAG
AGGCAGCAAATTAAAAATTTGAACATTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGT
GGAAGTTTCGTGCAGTCTTCAGACTCAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTAC
CAGCGTGAGTATGAGTGCCCAGACTTCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGAC
TGATGAAGCTATCTTTGAGTGTGATGAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAA
CCATGAGCGGATAAGACTCAAACCTGGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAG
GGCAATAGTGAGGTGCCAGACCTGCAAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCC
TGTTACTGTGTACAATGTCAGTAATCTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAA
GGTTGTGAGTTTCCTCCTAGTAGACGAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGA
TCAGCATCTGAAAGTGGTTTCCATTTTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGT
CTTTAAAACCTCCCCGACCCAGGAGTCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGA
AGGGCTCCTGGGGGCCACCGTGAATCTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAAC
TCATGCAGACCGGCTGCATAACGACCTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGC
CACCACTGCTCGCTGTGGCCTGGATGTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACT
GGGCTCTGATCATCCCTCAGAGGTGCCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCAT
TCACTACAAGGGAACGAGGACTTACAACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCAC
CCGTTCTCCCCGGCACCCGGGAGTCATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGA
ATCTTTCAAAAGTGAACACACTGTTTTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTA
TAATGGATTTCCAGTTCTTAGGAACAATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAG
TAGTCCTAATAGCCCTTTGCCCATGTTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCC
TCAGATGTGGTCTAGGTGTCTACTGCGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGT
CAGGGCTCTGAAAACAGCATATGATGTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTAT
GCAACTCTGTGGACAATATGATCAGCCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTAC
TTATGGTTATTATAATAAGGCTGTTTTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGT
TGTTTTAGGAGTAACACAGTTCAAAAGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGGTGGCCAGTCTGATCTTGG
ATATAATTCATTATCTAAAGATGAAGTTAGAAGAGGGGATACATCTACTGAAGACATTCAAGAAGAAAAAGATAAAAAAGGGAGTGATTG
TAGTTCCTTGTCAGAGAGTGAGAGTACAAAAGGAAGTGCTGATTGCCTTCCTAAGCTCAGTTATCAAAATTCTTCCAGTATCGTTCGCCT
CACTGGTACAAGTAACAACAGTGCTGGTAAAATATCAGGAGAAAGCATGGAAAGCACACCTGAGCTGCTCTTAATATCATCTCTTGAAGA
TACAAATGAAACACGAAACATTCAAAGTAGATGCTTCAGGAAAAGACATAAAAGTGACAATGAAACTAATTTGCAGCAGCAAGTGGTCTG
GGGAAATAGAAACCGTAATCTTAGTGGAGGGGTACTGATGGGATTTATGCTCAATAGAATTAACCAGGAAGCAACCCCTGGAGATATAGT
TGAAAAATTGGGAGCTGATGCAAAAATTCTTTCAAATGTTATCTCAAAAAGCACGAGACCAAATACTCTTGATATTGGGAAGCCACCTTT
AAGATCAAAAAGAGACAGTCTAGAAAAGGAATCTAGTGATGATGATACACCTTTTGATGGTTCTAACTATTTGGCAGATAAAGTGGATTC
TCCTGTTATTTTTGACTTAGAAGACTTAGACAGTGAAACAGATGTATCAAAAGCAGGATGTGTTGCTACACAAAATCCCAAGAGGATTCA
ACGTATGAACAGCAGCTTTTCAGTAAAACCTTTTGAAAAAACTGATGTCGCAACAGGATTTGATCCCCTCTCTCTTTTGGTTGCTGAGAC
TGAACAGCAGCAAAAAGAAGAAGAGGAGGAGGATGAAGATGATAGCAAAAGCATTTCAACACCATCTGCTAGGCGTGATTTAGCTGAAGA
AATTGTGATGTATATGAATAACATGAGCAGTCCTTTGACAAGTCGTACACCAAGCATTGATTTACAACGGGCATGTGATGATAAATTAAA
TAAGAAAAGTCCACCATTGGTCAAGGCATGCAGAAGATCTAGTCTGCCTCCTAATTCTCCTAAGCCAGTGAGACTTACCAAATCTAAAAG
TTACACAAAAAGTGAGGAGAAACCAAGGGATAGACTTTGGTCTTCTCCAGCCTTCTCACCTACTTGCCCATTTAGGGAAGAATCTCAGGA
TACATTAACCCACTCATCACCTTCATTTAACTTAGATACACTACTAGTACCTAAACTAGATGTTCTAAGAAACAGTATGTTCACTGCTGG
AAAAGGAGTTGCAGAGAAAGCAAGCAAATGGTATTCAAGATTCACCATGTACACCACATCATCTAAGGATCAAAGTTCTGATCGTACCAG
TCTTTCTTCAGTGGGAGCCCAGGATTCTGAATCTACCTCTTTAACAGATGAAGATGTCTGCCATGAGTTGGAAGGACCTATCTCCTCTCA
AGAGACCAGTGCTACTTCAGGGACTAAGAGAATTGATCTCAGCCGAATAAGCCTGGAAAGTTCTGCATCCTTGGAAGGATCTCTGTCGAA
GTTTGCCTTACCTGGGAAATCAGAAGTGACATCTTCCTTCAACGCGAGTAATACAAATATCTTCCAGAACTATGCAATGGAGGTTCTCAT
CTCAAGTTGCTCTCGGTGTAGAACTTGTGATTGTCTTGTCCATGATGAGGAAATCATGGCTGGCTGGACAGCAGATGATTCAAATCTCAA
TACTACATGCCCATTCTGTGGCAATATCTTCTTACCCTTTCTGAATATAGAAATAAGAGATTTAAGACGACCTGGAAGATACTTTCTAAA
GTCAAGCCCATCAACAGAAAATATGCACTTTCCATCCTCCATTTCAAGTCAGACGAGGCAGTCTTGCATTTCAACATCAGCCTCTGGTCT
TGACACATCTGCTCTCTCTGTTCAAGGGAATTTTGATCTAAATAGCAAATCTAAACTGCAGGAAAATTTTTGCACCCGAAGTATTCAGAT
CCCTGCTAATAGATCAAAAACAGCTATGTCTAAATGTCCAATATTTCCAATGGCCAGGAGTATTAGTACTTCTGGCCCCTTGGATAAGGA
AGATACTGGAAGACAGAAGCTCATTTCTACAGGCAGCCTGCCAGCTACTTTACAAGGAGCTACAGATTCTTTAGGTTTAGAATGGCACCT
TCCAAGTCCCGATCCTGTCACTGTTCCGTATCTTAGTCCTTTAGTGGTATGGAAAGAACTTGAAAGCTTATTGGAAAATGAAGGTGATCA
TGCAATAACAGTAGCAGACTTTGTGGACCATCATCCAATTGTTTTTTGGAACCTGGTATGGTATTTCAGACGTCTTGACTTGCCCAGTAA
CTTACCTGGATTGATTCTTTCTTCTGAGCACTGTAACAAGTATTCAAAGATTCCCCGCCACTGTATGTCTGAAGATAGCAAATATGTTTT
AATACAAATGTTATGGGACAATATGAAGTTACATCAGGATCCGGGACAGCCCTTGTACATTCTCTGGAATGCACACACCCAAAAATATCC
AATGGTCCATTTATTGCAAAAAAGTGATAACTCATTTAACCAGGAACTGTTGAAAAGTATGGTAAAAAGCATTAAAATGAATGATGTCTA
TGGACCAATGAGTCAGATTTTAGAGACACTGAATAAGTGTCCACATTTTAAAAGACAGAGGAGTTTATACAGAGAAATACTATTTCTCTC
ACTTGTGGCACTGGGAAGAGAAAACATTGATATAGATGCTTTTGATAAAGAGTACAAGATGGCATACGATCGTCTCACACCTAGTCAAGT
CAAGAGTACACACAACTGTGATAGACCACCAAGTACAGGGGTGATGGAATGTCGAAAAACCTTTGGAGAACCTTATCTTTAAGATGTATT

>101159_101159_7_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000318876_DENND4A_chr15_65998562_ENST00000431932_length(amino acids)=1613AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGT
SNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDNETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKL
GADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDGSNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMN
SSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSISTPSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKS
PPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSPTCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGV
AEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFAL
PGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSP
STENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTG
RQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPG
LILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPM

--------------------------------------------------------------
>101159_101159_8_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000318876_DENND4A_chr15_65998562_ENST00000443035_length(transcript)=6846nt_BP=1843nt
TGTTAGTCCGAGCTGGGAGAAGTTCACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGA
GGGTGGCGGAGATGGAGATGAGGATGGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCG
CCTTGCTGCGGCCGAGCTTCTCAGTGGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCA
TTACCAAAACTTTGTAGCTGATGTCCAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCC
AAGTCAATTTTGACCACATCTTTGCTTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAG
AGGCAGCAAATTAAAAATTTGAACATTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGT
GGAAGTTTCGTGCAGTCTTCAGACTCAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTAC
CAGCGTGAGTATGAGTGCCCAGACTTCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGAC
TGATGAAGCTATCTTTGAGTGTGATGAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAA
CCATGAGCGGATAAGACTCAAACCTGGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAG
GGCAATAGTGAGGTGCCAGACCTGCAAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCC
TGTTACTGTGTACAATGTCAGTAATCTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAA
GGTTGTGAGTTTCCTCCTAGTAGACGAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGA
TCAGCATCTGAAAGTGGTTTCCATTTTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGT
CTTTAAAACCTCCCCGACCCAGGAGTCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGA
AGGGCTCCTGGGGGCCACCGTGAATCTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAAC
TCATGCAGACCGGCTGCATAACGACCTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGC
CACCACTGCTCGCTGTGGCCTGGATGTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACT
GGGCTCTGATCATCCCTCAGAGGTGCCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCAT
TCACTACAAGGGAACGAGGACTTACAACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCAC
CCGTTCTCCCCGGCACCCGGGAGTCATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGA
ATCTTTCAAAAGTGAACACACTGTTTTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTA
TAATGGATTTCCAGTTCTTAGGAACAATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAG
TAGTCCTAATAGCCCTTTGCCCATGTTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCC
TCAGATGTGGTCTAGGTGTCTACTGCGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGT
CAGGGCTCTGAAAACAGCATATGATGTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTAT
GCAACTCTGTGGACAATATGATCAGCCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTAC
TTATGGTTATTATAATAAGGCTGTTTTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGT
TGTTTTAGGAGTAACACAGTTCAAAAGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGATGGCAGTGACCTGGATGC
TGTTAGTCATGGCAGCATGGATAGTGGTCATGGGACACACACTGTGGAGCAGGCACCTTTTAATACGGGTTTAATCAAAGTATATGCTAC
TGATGATAGATCTAGTACAGGTGGCCAGTCTGATCTTGGATATAATTCATTATCTAAAGATGAAGTTAGAAGAGGGGATACATCTACTGA
AGACATTCAAGAAGAAAAAGATAAAAAAGGGAGTGATTGTAGTTCCTTGTCAGAGAGTGAGAGTACAAAAGGAAGTGCTGATTGCCTTCC
TAAGCTCAGTTATCAAAATTCTTCCAGTATCGTTCGCCTCACTGGTACAAGTAACAACAGTGCTGGTAAAATATCAGGAGAAAGCATGGA
AAGCACACCTGAGCTGCTCTTAATATCATCTCTTGAAGATACAAATGAAACACGAAACATTCAAAGTAGATGCTTCAGGAAAAGACATAA
AAGTGACAATGAAACTAATTTGCAGCAGCAAGTGGTCTGGGGAAATAGAAACCGTAATCTTAGTGGAGGGGTACTGATGGGATTTATGCT
CAATAGAATTAACCAGGAAGCAACCCCTGGAGATATAGTTGAAAAATTGGGAGCTGATGCAAAAATTCTTTCAAATGTTATCTCAAAAAG
CACGAGACCAAATACTCTTGATATTGGGAAGCCACCTTTAAGATCAAAAAGAGACAGTCTAGAAAAGGAATCTAGTGATGATGATACACC
TTTTGATGGTTCTAACTATTTGGCAGATAAAGTGGATTCTCCTGTTATTTTTGACTTAGAAGACTTAGACAGTGAAACAGATGTATCAAA
AGCAGGATGTGTTGCTACACAAAATCCCAAGAGGATTCAACGTATGAACAGCAGCTTTTCAGTAAAACCTTTTGAAAAAACTGATGTCGC
AACAGGATTTGATCCCCTCTCTCTTTTGGTTGCTGAGACTGAACAGCAGCAAAAAGAAGAAGAGGAGGAGGATGAAGATGATAGCAAAAG
CATTTCAACACCATCTGCTAGGCGTGATTTAGCTGAAGAAATTGTGATGTATATGAATAACATGAGCAGTCCTTTGACAAGTCGTACACC
AAGCATTGATTTACAACGGGCATGTGATGATAAATTAAATAAGAAAAGTCCACCATTGGTCAAGGCATGCAGAAGATCTAGTCTGCCTCC
TAATTCTCCTAAGCCAGTGAGACTTACCAAATCTAAAAGTTACACAAAAAGTGAGGAGAAACCAAGGGATAGACTTTGGTCTTCTCCAGC
CTTCTCACCTACTTGCCCATTTAGGGAAGAATCTCAGGATACATTAACCCACTCATCACCTTCATTTAACTTAGATACACTACTAGTACC
TAAACTAGATGTTCTAAGAAACAGTATGTTCACTGCTGGAAAAGGAGTTGCAGAGAAAGCAAGCAAATGGTATTCAAGATTCACCATGTA
CACCACATCATCTAAGGATCAAAGTTCTGATCGTACCAGTCTTTCTTCAGTGGGAGCCCAGGATTCTGAATCTACCTCTTTAACAGATGA
AGATGTCTGCCATGAGTTGGAAGGACCTATCTCCTCTCAAGAGACCAGTGCTACTTCAGGGACTAAGAGAATTGATCTCAGCCGAATAAG
CCTGGAAAGTTCTGCATCCTTGGAAGGATCTCTGTCGAAGTTTGCCTTACCTGGGAAATCAGAAGTGACATCTTCCTTCAACGCGAGTAA
TACAAATATCTTCCAGAACTATGCAATGGAGGTTCTCATCTCAAGTTGCTCTCGGTGTAGAACTTGTGATTGTCTTGTCCATGATGAGGA
AATCATGGCTGGCTGGACAGCAGATGATTCAAATCTCAATACTACATGCCCATTCTGTGGCAATATCTTCTTACCCTTTCTGAATATAGA
AATAAGAGATTTAAGACGACCTGGAAGATACTTTCTAAAGTCAAGCCCATCAACAGAAAATATGCACTTTCCATCCTCCATTTCAAGTCA
GACGAGGCAGTCTTGCATTTCAACATCAGCCTCTGGTCTTGACACATCTGCTCTCTCTGTTCAAGGGAATTTTGATCTAAATAGCAAATC
TAAACTGCAGGAAAATTTTTGCACCCGAAGTATTCAGATCCCTGCTAATAGATCAAAAACAGCTATGTCTAAATGTCCAATATTTCCAAT
GGCCAGGAGTATTAGTACTTCTGGCCCCTTGGATAAGGAAGATACTGGAAGACAGAAGCTCATTTCTACAGGCAGCCTGCCAGCTACTTT
ACAAGGAGCTACAGATTCTTTAGGTTTAGAATGGCACCTTCCAAGTCCCGATCCTGTCACTGTTCCGTATCTTAGTCCTTTAGTGGTATG
GAAAGAACTTGAAAGCTTATTGGAAAATGAAGGTGATCATGCAATAACAGTAGCAGACTTTGTGGACCATCATCCAATTGTTTTTTGGAA
CCTGGTATGGTATTTCAGACGTCTTGACTTGCCCAGTAACTTACCTGGATTGATTCTTTCTTCTGAGCACTGTAACAAGTATTCAAAGAT
TCCCCGCCACTGTATGTCTGAAGATAGCAAATATGTTTTAATACAAATGTTATGGGACAATATGAAGTTACATCAGGATCCGGGACAGCC
CTTGTACATTCTCTGGAATGCACACACCCAAAAATATCCAATGGTCCATTTATTGCAAAAAAGTGATAACTCATTTAACCAGGAACTGTT
GAAAAGTATGGTAAAAAGCATTAAAATGAATGATGTCTATGGACCAATGAGTCAGATTTTAGAGACACTGAATAAGTGTCCACATTTTAA
AAGACAGAGGAGTTTATACAGAGAAATACTATTTCTCTCACTTGTGGCACTGGGAAGAGAAAACATTGATATAGATGCTTTTGATAAAGA
GTACAAGATGGCATACGATCGTCTCACACCTAGTCAAGTCAAGAGTACACACAACTGTGATAGACCACCAAGTACAGGGGTGATGGAATG
TCGAAAAACCTTTGGAGAACCTTATCTTTAAGATGTATTTGTATGTGTAAACATTCAATGTATATTGTATAGTCAGTGTATAAAATAACA
CTTTTAGACTCTAAATATTTTTTCTTCAATTTTTGAAAATACAATTTGTAAATGGTTCAAAAGACTCAGACAGCTTATGTACAGAATGTT
TGAAGAAGAGAATAGTGACAAGTGGGGAGAAAGCCACTTTGTTTCTCATTTCTTTTTTCTTCTTCTTTAACTCCCCTGTAATAGGAAATA
AAGTATTTTTGTGATGAGGAAATCCCTAAACAAAATTAGTTGCCATAAAATATGACAACTGCTTTATGGTTTCTTTTGGAAGAGACAGAT
TGAAAAATCATGAATGGAATCTAAACAGAAATGTCAGATGAACGTATTTCCTGTTTTCATAGACTATTCAAATGTTTTGACCATGAAGTT
GTATTATACATATTTTAAATTGTTTATAGTAAGTTGATATTTTTTTAATTTTTAAATTTAATATAGCAAACTTAAAATGAATTTAAACTT
AAGCAAGCAAGCGTGTATTTTCCTTGTCTGCTGCTATTTGAAGTAATTAGTACAGCTGCAGATCTCTCTGTGTATATCTATCTATATATA
TATTTTTTATTACTTGGGAGAATGAATTTTAAAATGTCAGTGCTAGTGTCAAGTGTTGTCCTAGGATTGCATGTTAGTACCCCTAAGCCT
GAGTGTGGGGAGTGAGTTATGCAAGGGTAGCGTGCACTGCCCAGACTGACTCATGGAGCCTTGTGCAAGGAGAGCCAGAGAGGTTCACTA
TACCATGACTCCAAAATTGTCTCTATTGCTAATAGATACGTATAGTATACAGGGAAAACAGCTTATAAATCCAAATATCAATTTAAATTT
TAATATTCTACATGAAAACTTACATTGGGAAATATGCAGACAAGTGATTATATTCCAAATTTTACCCTTATTTTAATATCTAAAATATTG
GGTATGATGCAAATTATACTATAGAATATTTATCTGAAATATGACTTACTGGGGTATTCTGTTAATACTATATATAAATATTCAGAATTT
TTTTCAAAAGTAGAAAAATTCCCCTCTAAAAGTACAGCCAGATAGATTTTCATCCATATTGAGGAACTTAGCTTTTTCAACAAGCTTCAG
AATCTGAAGTCTGTAGAATCTAAAATACAGAAATATCCAGAAATCAGACAATAAATTGAAAGTTTAGACATCATGAGTATTAAATAGCTT

>101159_101159_8_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000318876_DENND4A_chr15_65998562_ENST00000443035_length(amino acids)=1656AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSDGSDLDAVSHGSMDSGHGTHTVEQAPFNTGLIKVYATDDRSSTGGQSDLGYNSLSKDEVRRGDTSTEDIQ
EEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGTSNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDN
ETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKLGADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDG
SNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMNSSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSIST
PSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKSPPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSP
TCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVC
HELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFALPGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMA
GWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQ
ENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKEL
ESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYI
LWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKM

--------------------------------------------------------------
>101159_101159_9_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000553891_DENND4A_chr15_65998562_ENST00000431932_length(transcript)=5531nt_BP=1818nt
ACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGAGGGTGGCGGAGATGGAGATGAGGAT
GGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCGCCTTGCTGCGGCCGAGCTTCTCAGT
GGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCATTACCAAAACTTTGTAGCTGATGTC
CAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCCAAGTCAATTTTGACCACATCTTTGC
TTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAGAGGCAGCAAATTAAAAATTTGAACA
TTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGTGGAAGTTTCGTGCAGTCTTCAGACT
CAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTACCAGCGTGAGTATGAGTGCCCAGACT
TCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGACTGATGAAGCTATCTTTGAGTGTGAT
GAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAACCATGAGCGGATAAGACTCAAACCT
GGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAGGGCAATAGTGAGGTGCCAGACCTGC
AAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCCTGTTACTGTGTACAATGTCAGTAAT
CTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAAGGTTGTGAGTTTCCTCCTAGTAGAC
GAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGATCAGCATCTGAAAGTGGTTTCCATT
TTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGTCTTTAAAACCTCCCCGACCCAGGAG
TCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGAAGGGCTCCTGGGGGCCACCGTGAAT
CTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAACTCATGCAGACCGGCTGCATAACGAC
CTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGCCACCACTGCTCGCTGTGGCCTGGAT
GTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACTGGGCTCTGATCATCCCTCAGAGGTG
CCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCATTCACTACAAGGGAACGAGGACTTAC
AACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCACCCGTTCTCCCCGGCACCCGGGAGTC
ATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGAATCTTTCAAAAGTGAACACACTGTT
TTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTATAATGGATTTCCAGTTCTTAGGAAC
AATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAGTAGTCCTAATAGCCCTTTGCCCATG
TTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCCTCAGATGTGGTCTAGGTGTCTACTG
CGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGTCAGGGCTCTGAAAACAGCATATGAT
GTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTATGCAACTCTGTGGACAATATGATCAG
CCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTACTTATGGTTATTATAATAAGGCTGTT
TTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGTTGTTTTAGGAGTAACACAGTTCAAA
AGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGGTGGCCAGTCTGATCTTGGATATAATTCATTATCTAAAGATGAA
GTTAGAAGAGGGGATACATCTACTGAAGACATTCAAGAAGAAAAAGATAAAAAAGGGAGTGATTGTAGTTCCTTGTCAGAGAGTGAGAGT
ACAAAAGGAAGTGCTGATTGCCTTCCTAAGCTCAGTTATCAAAATTCTTCCAGTATCGTTCGCCTCACTGGTACAAGTAACAACAGTGCT
GGTAAAATATCAGGAGAAAGCATGGAAAGCACACCTGAGCTGCTCTTAATATCATCTCTTGAAGATACAAATGAAACACGAAACATTCAA
AGTAGATGCTTCAGGAAAAGACATAAAAGTGACAATGAAACTAATTTGCAGCAGCAAGTGGTCTGGGGAAATAGAAACCGTAATCTTAGT
GGAGGGGTACTGATGGGATTTATGCTCAATAGAATTAACCAGGAAGCAACCCCTGGAGATATAGTTGAAAAATTGGGAGCTGATGCAAAA
ATTCTTTCAAATGTTATCTCAAAAAGCACGAGACCAAATACTCTTGATATTGGGAAGCCACCTTTAAGATCAAAAAGAGACAGTCTAGAA
AAGGAATCTAGTGATGATGATACACCTTTTGATGGTTCTAACTATTTGGCAGATAAAGTGGATTCTCCTGTTATTTTTGACTTAGAAGAC
TTAGACAGTGAAACAGATGTATCAAAAGCAGGATGTGTTGCTACACAAAATCCCAAGAGGATTCAACGTATGAACAGCAGCTTTTCAGTA
AAACCTTTTGAAAAAACTGATGTCGCAACAGGATTTGATCCCCTCTCTCTTTTGGTTGCTGAGACTGAACAGCAGCAAAAAGAAGAAGAG
GAGGAGGATGAAGATGATAGCAAAAGCATTTCAACACCATCTGCTAGGCGTGATTTAGCTGAAGAAATTGTGATGTATATGAATAACATG
AGCAGTCCTTTGACAAGTCGTACACCAAGCATTGATTTACAACGGGCATGTGATGATAAATTAAATAAGAAAAGTCCACCATTGGTCAAG
GCATGCAGAAGATCTAGTCTGCCTCCTAATTCTCCTAAGCCAGTGAGACTTACCAAATCTAAAAGTTACACAAAAAGTGAGGAGAAACCA
AGGGATAGACTTTGGTCTTCTCCAGCCTTCTCACCTACTTGCCCATTTAGGGAAGAATCTCAGGATACATTAACCCACTCATCACCTTCA
TTTAACTTAGATACACTACTAGTACCTAAACTAGATGTTCTAAGAAACAGTATGTTCACTGCTGGAAAAGGAGTTGCAGAGAAAGCAAGC
AAATGGTATTCAAGATTCACCATGTACACCACATCATCTAAGGATCAAAGTTCTGATCGTACCAGTCTTTCTTCAGTGGGAGCCCAGGAT
TCTGAATCTACCTCTTTAACAGATGAAGATGTCTGCCATGAGTTGGAAGGACCTATCTCCTCTCAAGAGACCAGTGCTACTTCAGGGACT
AAGAGAATTGATCTCAGCCGAATAAGCCTGGAAAGTTCTGCATCCTTGGAAGGATCTCTGTCGAAGTTTGCCTTACCTGGGAAATCAGAA
GTGACATCTTCCTTCAACGCGAGTAATACAAATATCTTCCAGAACTATGCAATGGAGGTTCTCATCTCAAGTTGCTCTCGGTGTAGAACT
TGTGATTGTCTTGTCCATGATGAGGAAATCATGGCTGGCTGGACAGCAGATGATTCAAATCTCAATACTACATGCCCATTCTGTGGCAAT
ATCTTCTTACCCTTTCTGAATATAGAAATAAGAGATTTAAGACGACCTGGAAGATACTTTCTAAAGTCAAGCCCATCAACAGAAAATATG
CACTTTCCATCCTCCATTTCAAGTCAGACGAGGCAGTCTTGCATTTCAACATCAGCCTCTGGTCTTGACACATCTGCTCTCTCTGTTCAA
GGGAATTTTGATCTAAATAGCAAATCTAAACTGCAGGAAAATTTTTGCACCCGAAGTATTCAGATCCCTGCTAATAGATCAAAAACAGCT
ATGTCTAAATGTCCAATATTTCCAATGGCCAGGAGTATTAGTACTTCTGGCCCCTTGGATAAGGAAGATACTGGAAGACAGAAGCTCATT
TCTACAGGCAGCCTGCCAGCTACTTTACAAGGAGCTACAGATTCTTTAGGTTTAGAATGGCACCTTCCAAGTCCCGATCCTGTCACTGTT
CCGTATCTTAGTCCTTTAGTGGTATGGAAAGAACTTGAAAGCTTATTGGAAAATGAAGGTGATCATGCAATAACAGTAGCAGACTTTGTG
GACCATCATCCAATTGTTTTTTGGAACCTGGTATGGTATTTCAGACGTCTTGACTTGCCCAGTAACTTACCTGGATTGATTCTTTCTTCT
GAGCACTGTAACAAGTATTCAAAGATTCCCCGCCACTGTATGTCTGAAGATAGCAAATATGTTTTAATACAAATGTTATGGGACAATATG
AAGTTACATCAGGATCCGGGACAGCCCTTGTACATTCTCTGGAATGCACACACCCAAAAATATCCAATGGTCCATTTATTGCAAAAAAGT
GATAACTCATTTAACCAGGAACTGTTGAAAAGTATGGTAAAAAGCATTAAAATGAATGATGTCTATGGACCAATGAGTCAGATTTTAGAG
ACACTGAATAAGTGTCCACATTTTAAAAGACAGAGGAGTTTATACAGAGAAATACTATTTCTCTCACTTGTGGCACTGGGAAGAGAAAAC
ATTGATATAGATGCTTTTGATAAAGAGTACAAGATGGCATACGATCGTCTCACACCTAGTCAAGTCAAGAGTACACACAACTGTGATAGA
CCACCAAGTACAGGGGTGATGGAATGTCGAAAAACCTTTGGAGAACCTTATCTTTAAGATGTATTTGTATGTGTAAACATTCAATGTATA

>101159_101159_9_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000553891_DENND4A_chr15_65998562_ENST00000431932_length(amino acids)=1613AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGT
SNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDNETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKL
GADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDGSNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMN
SSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSISTPSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKS
PPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSPTCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGV
AEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFAL
PGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSP
STENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTG
RQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPG
LILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPM

--------------------------------------------------------------
>101159_101159_10_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000553891_DENND4A_chr15_65998562_ENST00000443035_length(transcript)=6821nt_BP=1818nt
ACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGAGGGTGGCGGAGATGGAGATGAGGAT
GGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCGCCTTGCTGCGGCCGAGCTTCTCAGT
GGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCATTACCAAAACTTTGTAGCTGATGTC
CAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCCAAGTCAATTTTGACCACATCTTTGC
TTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAGAGGCAGCAAATTAAAAATTTGAACA
TTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGTGGAAGTTTCGTGCAGTCTTCAGACT
CAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTACCAGCGTGAGTATGAGTGCCCAGACT
TCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGACTGATGAAGCTATCTTTGAGTGTGAT
GAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAACCATGAGCGGATAAGACTCAAACCT
GGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAGGGCAATAGTGAGGTGCCAGACCTGC
AAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCCTGTTACTGTGTACAATGTCAGTAAT
CTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAAGGTTGTGAGTTTCCTCCTAGTAGAC
GAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGATCAGCATCTGAAAGTGGTTTCCATT
TTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGTCTTTAAAACCTCCCCGACCCAGGAG
TCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGAAGGGCTCCTGGGGGCCACCGTGAAT
CTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAACTCATGCAGACCGGCTGCATAACGAC
CTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGCCACCACTGCTCGCTGTGGCCTGGAT
GTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACTGGGCTCTGATCATCCCTCAGAGGTG
CCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCATTCACTACAAGGGAACGAGGACTTAC
AACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCACCCGTTCTCCCCGGCACCCGGGAGTC
ATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGAATCTTTCAAAAGTGAACACACTGTT
TTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTATAATGGATTTCCAGTTCTTAGGAAC
AATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAGTAGTCCTAATAGCCCTTTGCCCATG
TTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCCTCAGATGTGGTCTAGGTGTCTACTG
CGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGTCAGGGCTCTGAAAACAGCATATGAT
GTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTATGCAACTCTGTGGACAATATGATCAG
CCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTACTTATGGTTATTATAATAAGGCTGTT
TTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGTTGTTTTAGGAGTAACACAGTTCAAA
AGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGATGGCAGTGACCTGGATGCTGTTAGTCATGGCAGCATGGATAGT
GGTCATGGGACACACACTGTGGAGCAGGCACCTTTTAATACGGGTTTAATCAAAGTATATGCTACTGATGATAGATCTAGTACAGGTGGC
CAGTCTGATCTTGGATATAATTCATTATCTAAAGATGAAGTTAGAAGAGGGGATACATCTACTGAAGACATTCAAGAAGAAAAAGATAAA
AAAGGGAGTGATTGTAGTTCCTTGTCAGAGAGTGAGAGTACAAAAGGAAGTGCTGATTGCCTTCCTAAGCTCAGTTATCAAAATTCTTCC
AGTATCGTTCGCCTCACTGGTACAAGTAACAACAGTGCTGGTAAAATATCAGGAGAAAGCATGGAAAGCACACCTGAGCTGCTCTTAATA
TCATCTCTTGAAGATACAAATGAAACACGAAACATTCAAAGTAGATGCTTCAGGAAAAGACATAAAAGTGACAATGAAACTAATTTGCAG
CAGCAAGTGGTCTGGGGAAATAGAAACCGTAATCTTAGTGGAGGGGTACTGATGGGATTTATGCTCAATAGAATTAACCAGGAAGCAACC
CCTGGAGATATAGTTGAAAAATTGGGAGCTGATGCAAAAATTCTTTCAAATGTTATCTCAAAAAGCACGAGACCAAATACTCTTGATATT
GGGAAGCCACCTTTAAGATCAAAAAGAGACAGTCTAGAAAAGGAATCTAGTGATGATGATACACCTTTTGATGGTTCTAACTATTTGGCA
GATAAAGTGGATTCTCCTGTTATTTTTGACTTAGAAGACTTAGACAGTGAAACAGATGTATCAAAAGCAGGATGTGTTGCTACACAAAAT
CCCAAGAGGATTCAACGTATGAACAGCAGCTTTTCAGTAAAACCTTTTGAAAAAACTGATGTCGCAACAGGATTTGATCCCCTCTCTCTT
TTGGTTGCTGAGACTGAACAGCAGCAAAAAGAAGAAGAGGAGGAGGATGAAGATGATAGCAAAAGCATTTCAACACCATCTGCTAGGCGT
GATTTAGCTGAAGAAATTGTGATGTATATGAATAACATGAGCAGTCCTTTGACAAGTCGTACACCAAGCATTGATTTACAACGGGCATGT
GATGATAAATTAAATAAGAAAAGTCCACCATTGGTCAAGGCATGCAGAAGATCTAGTCTGCCTCCTAATTCTCCTAAGCCAGTGAGACTT
ACCAAATCTAAAAGTTACACAAAAAGTGAGGAGAAACCAAGGGATAGACTTTGGTCTTCTCCAGCCTTCTCACCTACTTGCCCATTTAGG
GAAGAATCTCAGGATACATTAACCCACTCATCACCTTCATTTAACTTAGATACACTACTAGTACCTAAACTAGATGTTCTAAGAAACAGT
ATGTTCACTGCTGGAAAAGGAGTTGCAGAGAAAGCAAGCAAATGGTATTCAAGATTCACCATGTACACCACATCATCTAAGGATCAAAGT
TCTGATCGTACCAGTCTTTCTTCAGTGGGAGCCCAGGATTCTGAATCTACCTCTTTAACAGATGAAGATGTCTGCCATGAGTTGGAAGGA
CCTATCTCCTCTCAAGAGACCAGTGCTACTTCAGGGACTAAGAGAATTGATCTCAGCCGAATAAGCCTGGAAAGTTCTGCATCCTTGGAA
GGATCTCTGTCGAAGTTTGCCTTACCTGGGAAATCAGAAGTGACATCTTCCTTCAACGCGAGTAATACAAATATCTTCCAGAACTATGCA
ATGGAGGTTCTCATCTCAAGTTGCTCTCGGTGTAGAACTTGTGATTGTCTTGTCCATGATGAGGAAATCATGGCTGGCTGGACAGCAGAT
GATTCAAATCTCAATACTACATGCCCATTCTGTGGCAATATCTTCTTACCCTTTCTGAATATAGAAATAAGAGATTTAAGACGACCTGGA
AGATACTTTCTAAAGTCAAGCCCATCAACAGAAAATATGCACTTTCCATCCTCCATTTCAAGTCAGACGAGGCAGTCTTGCATTTCAACA
TCAGCCTCTGGTCTTGACACATCTGCTCTCTCTGTTCAAGGGAATTTTGATCTAAATAGCAAATCTAAACTGCAGGAAAATTTTTGCACC
CGAAGTATTCAGATCCCTGCTAATAGATCAAAAACAGCTATGTCTAAATGTCCAATATTTCCAATGGCCAGGAGTATTAGTACTTCTGGC
CCCTTGGATAAGGAAGATACTGGAAGACAGAAGCTCATTTCTACAGGCAGCCTGCCAGCTACTTTACAAGGAGCTACAGATTCTTTAGGT
TTAGAATGGCACCTTCCAAGTCCCGATCCTGTCACTGTTCCGTATCTTAGTCCTTTAGTGGTATGGAAAGAACTTGAAAGCTTATTGGAA
AATGAAGGTGATCATGCAATAACAGTAGCAGACTTTGTGGACCATCATCCAATTGTTTTTTGGAACCTGGTATGGTATTTCAGACGTCTT
GACTTGCCCAGTAACTTACCTGGATTGATTCTTTCTTCTGAGCACTGTAACAAGTATTCAAAGATTCCCCGCCACTGTATGTCTGAAGAT
AGCAAATATGTTTTAATACAAATGTTATGGGACAATATGAAGTTACATCAGGATCCGGGACAGCCCTTGTACATTCTCTGGAATGCACAC
ACCCAAAAATATCCAATGGTCCATTTATTGCAAAAAAGTGATAACTCATTTAACCAGGAACTGTTGAAAAGTATGGTAAAAAGCATTAAA
ATGAATGATGTCTATGGACCAATGAGTCAGATTTTAGAGACACTGAATAAGTGTCCACATTTTAAAAGACAGAGGAGTTTATACAGAGAA
ATACTATTTCTCTCACTTGTGGCACTGGGAAGAGAAAACATTGATATAGATGCTTTTGATAAAGAGTACAAGATGGCATACGATCGTCTC
ACACCTAGTCAAGTCAAGAGTACACACAACTGTGATAGACCACCAAGTACAGGGGTGATGGAATGTCGAAAAACCTTTGGAGAACCTTAT
CTTTAAGATGTATTTGTATGTGTAAACATTCAATGTATATTGTATAGTCAGTGTATAAAATAACACTTTTAGACTCTAAATATTTTTTCT
TCAATTTTTGAAAATACAATTTGTAAATGGTTCAAAAGACTCAGACAGCTTATGTACAGAATGTTTGAAGAAGAGAATAGTGACAAGTGG
GGAGAAAGCCACTTTGTTTCTCATTTCTTTTTTCTTCTTCTTTAACTCCCCTGTAATAGGAAATAAAGTATTTTTGTGATGAGGAAATCC
CTAAACAAAATTAGTTGCCATAAAATATGACAACTGCTTTATGGTTTCTTTTGGAAGAGACAGATTGAAAAATCATGAATGGAATCTAAA
CAGAAATGTCAGATGAACGTATTTCCTGTTTTCATAGACTATTCAAATGTTTTGACCATGAAGTTGTATTATACATATTTTAAATTGTTT
ATAGTAAGTTGATATTTTTTTAATTTTTAAATTTAATATAGCAAACTTAAAATGAATTTAAACTTAAGCAAGCAAGCGTGTATTTTCCTT
GTCTGCTGCTATTTGAAGTAATTAGTACAGCTGCAGATCTCTCTGTGTATATCTATCTATATATATATTTTTTATTACTTGGGAGAATGA
ATTTTAAAATGTCAGTGCTAGTGTCAAGTGTTGTCCTAGGATTGCATGTTAGTACCCCTAAGCCTGAGTGTGGGGAGTGAGTTATGCAAG
GGTAGCGTGCACTGCCCAGACTGACTCATGGAGCCTTGTGCAAGGAGAGCCAGAGAGGTTCACTATACCATGACTCCAAAATTGTCTCTA
TTGCTAATAGATACGTATAGTATACAGGGAAAACAGCTTATAAATCCAAATATCAATTTAAATTTTAATATTCTACATGAAAACTTACAT
TGGGAAATATGCAGACAAGTGATTATATTCCAAATTTTACCCTTATTTTAATATCTAAAATATTGGGTATGATGCAAATTATACTATAGA
ATATTTATCTGAAATATGACTTACTGGGGTATTCTGTTAATACTATATATAAATATTCAGAATTTTTTTCAAAAGTAGAAAAATTCCCCT
CTAAAAGTACAGCCAGATAGATTTTCATCCATATTGAGGAACTTAGCTTTTTCAACAAGCTTCAGAATCTGAAGTCTGTAGAATCTAAAA

>101159_101159_10_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000553891_DENND4A_chr15_65998562_ENST00000443035_length(amino acids)=1656AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSDGSDLDAVSHGSMDSGHGTHTVEQAPFNTGLIKVYATDDRSSTGGQSDLGYNSLSKDEVRRGDTSTEDIQ
EEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGTSNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDN
ETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKLGADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDG
SNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMNSSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSIST
PSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKSPPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSP
TCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVC
HELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFALPGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMA
GWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQ
ENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKEL
ESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYI
LWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKM

--------------------------------------------------------------
>101159_101159_11_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000556143_DENND4A_chr15_65998562_ENST00000431932_length(transcript)=5637nt_BP=1924nt
AGTGCGCACTACGCCCTTGCTGGCGCCGGGATCCTCCCTCTCTCGCTCCTCCCTTTCTGGGCTGCACCGCTCACGCCTTCCTGTTAGTCC
GAGCTGGGAGAAGTTCACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGAGGGTGGCGG
AGATGGAGATGAGGATGGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCGCCTTGCTGC
GGCCGAGCTTCTCAGTGGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCATTACCAAAA
CTTTGTAGCTGATGTCCAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCCAAGTCAATT
TTGACCACATCTTTGCTTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAGAGGCAGCAA
ATTAAAAATTTGAACATTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGTGGAAGTTTC
GTGCAGTCTTCAGACTCAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTACCAGCGTGAG
TATGAGTGCCCAGACTTCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGACTGATGAAGC
TATCTTTGAGTGTGATGAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAACCATGAGCG
GATAAGACTCAAACCTGGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAGGGCAATAGT
GAGGTGCCAGACCTGCAAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCCTGTTACTGT
GTACAATGTCAGTAATCTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAAGGTTGTGAG
TTTCCTCCTAGTAGACGAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGATCAGCATCT
GAAAGTGGTTTCCATTTTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGTCTTTAAAAC
CTCCCCGACCCAGGAGTCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGAAGGGCTCCT
GGGGGCCACCGTGAATCTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAACTCATGCAGA
CCGGCTGCATAACGACCTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGCCACCACTGC
TCGCTGTGGCCTGGATGTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACTGGGCTCTGA
TCATCCCTCAGAGGTGCCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCATTCACTACAA
GGGAACGAGGACTTACAACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCACCCGTTCTCC
CCGGCACCCGGGAGTCATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGAATCTTTCAA
AAGTGAACACACTGTTTTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTATAATGGATT
TCCAGTTCTTAGGAACAATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAGTAGTCCTAA
TAGCCCTTTGCCCATGTTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCCTCAGATGTG
GTCTAGGTGTCTACTGCGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGTCAGGGCTCT
GAAAACAGCATATGATGTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTATGCAACTCTG
TGGACAATATGATCAGCCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTACTTATGGTTA
TTATAATAAGGCTGTTTTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGTTGTTTTAGG
AGTAACACAGTTCAAAAGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGGTGGCCAGTCTGATCTTGGATATAATTC
ATTATCTAAAGATGAAGTTAGAAGAGGGGATACATCTACTGAAGACATTCAAGAAGAAAAAGATAAAAAAGGGAGTGATTGTAGTTCCTT
GTCAGAGAGTGAGAGTACAAAAGGAAGTGCTGATTGCCTTCCTAAGCTCAGTTATCAAAATTCTTCCAGTATCGTTCGCCTCACTGGTAC
AAGTAACAACAGTGCTGGTAAAATATCAGGAGAAAGCATGGAAAGCACACCTGAGCTGCTCTTAATATCATCTCTTGAAGATACAAATGA
AACACGAAACATTCAAAGTAGATGCTTCAGGAAAAGACATAAAAGTGACAATGAAACTAATTTGCAGCAGCAAGTGGTCTGGGGAAATAG
AAACCGTAATCTTAGTGGAGGGGTACTGATGGGATTTATGCTCAATAGAATTAACCAGGAAGCAACCCCTGGAGATATAGTTGAAAAATT
GGGAGCTGATGCAAAAATTCTTTCAAATGTTATCTCAAAAAGCACGAGACCAAATACTCTTGATATTGGGAAGCCACCTTTAAGATCAAA
AAGAGACAGTCTAGAAAAGGAATCTAGTGATGATGATACACCTTTTGATGGTTCTAACTATTTGGCAGATAAAGTGGATTCTCCTGTTAT
TTTTGACTTAGAAGACTTAGACAGTGAAACAGATGTATCAAAAGCAGGATGTGTTGCTACACAAAATCCCAAGAGGATTCAACGTATGAA
CAGCAGCTTTTCAGTAAAACCTTTTGAAAAAACTGATGTCGCAACAGGATTTGATCCCCTCTCTCTTTTGGTTGCTGAGACTGAACAGCA
GCAAAAAGAAGAAGAGGAGGAGGATGAAGATGATAGCAAAAGCATTTCAACACCATCTGCTAGGCGTGATTTAGCTGAAGAAATTGTGAT
GTATATGAATAACATGAGCAGTCCTTTGACAAGTCGTACACCAAGCATTGATTTACAACGGGCATGTGATGATAAATTAAATAAGAAAAG
TCCACCATTGGTCAAGGCATGCAGAAGATCTAGTCTGCCTCCTAATTCTCCTAAGCCAGTGAGACTTACCAAATCTAAAAGTTACACAAA
AAGTGAGGAGAAACCAAGGGATAGACTTTGGTCTTCTCCAGCCTTCTCACCTACTTGCCCATTTAGGGAAGAATCTCAGGATACATTAAC
CCACTCATCACCTTCATTTAACTTAGATACACTACTAGTACCTAAACTAGATGTTCTAAGAAACAGTATGTTCACTGCTGGAAAAGGAGT
TGCAGAGAAAGCAAGCAAATGGTATTCAAGATTCACCATGTACACCACATCATCTAAGGATCAAAGTTCTGATCGTACCAGTCTTTCTTC
AGTGGGAGCCCAGGATTCTGAATCTACCTCTTTAACAGATGAAGATGTCTGCCATGAGTTGGAAGGACCTATCTCCTCTCAAGAGACCAG
TGCTACTTCAGGGACTAAGAGAATTGATCTCAGCCGAATAAGCCTGGAAAGTTCTGCATCCTTGGAAGGATCTCTGTCGAAGTTTGCCTT
ACCTGGGAAATCAGAAGTGACATCTTCCTTCAACGCGAGTAATACAAATATCTTCCAGAACTATGCAATGGAGGTTCTCATCTCAAGTTG
CTCTCGGTGTAGAACTTGTGATTGTCTTGTCCATGATGAGGAAATCATGGCTGGCTGGACAGCAGATGATTCAAATCTCAATACTACATG
CCCATTCTGTGGCAATATCTTCTTACCCTTTCTGAATATAGAAATAAGAGATTTAAGACGACCTGGAAGATACTTTCTAAAGTCAAGCCC
ATCAACAGAAAATATGCACTTTCCATCCTCCATTTCAAGTCAGACGAGGCAGTCTTGCATTTCAACATCAGCCTCTGGTCTTGACACATC
TGCTCTCTCTGTTCAAGGGAATTTTGATCTAAATAGCAAATCTAAACTGCAGGAAAATTTTTGCACCCGAAGTATTCAGATCCCTGCTAA
TAGATCAAAAACAGCTATGTCTAAATGTCCAATATTTCCAATGGCCAGGAGTATTAGTACTTCTGGCCCCTTGGATAAGGAAGATACTGG
AAGACAGAAGCTCATTTCTACAGGCAGCCTGCCAGCTACTTTACAAGGAGCTACAGATTCTTTAGGTTTAGAATGGCACCTTCCAAGTCC
CGATCCTGTCACTGTTCCGTATCTTAGTCCTTTAGTGGTATGGAAAGAACTTGAAAGCTTATTGGAAAATGAAGGTGATCATGCAATAAC
AGTAGCAGACTTTGTGGACCATCATCCAATTGTTTTTTGGAACCTGGTATGGTATTTCAGACGTCTTGACTTGCCCAGTAACTTACCTGG
ATTGATTCTTTCTTCTGAGCACTGTAACAAGTATTCAAAGATTCCCCGCCACTGTATGTCTGAAGATAGCAAATATGTTTTAATACAAAT
GTTATGGGACAATATGAAGTTACATCAGGATCCGGGACAGCCCTTGTACATTCTCTGGAATGCACACACCCAAAAATATCCAATGGTCCA
TTTATTGCAAAAAAGTGATAACTCATTTAACCAGGAACTGTTGAAAAGTATGGTAAAAAGCATTAAAATGAATGATGTCTATGGACCAAT
GAGTCAGATTTTAGAGACACTGAATAAGTGTCCACATTTTAAAAGACAGAGGAGTTTATACAGAGAAATACTATTTCTCTCACTTGTGGC
ACTGGGAAGAGAAAACATTGATATAGATGCTTTTGATAAAGAGTACAAGATGGCATACGATCGTCTCACACCTAGTCAAGTCAAGAGTAC
ACACAACTGTGATAGACCACCAAGTACAGGGGTGATGGAATGTCGAAAAACCTTTGGAGAACCTTATCTTTAAGATGTATTTGTATGTGT

>101159_101159_11_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000556143_DENND4A_chr15_65998562_ENST00000431932_length(amino acids)=1613AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGT
SNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDNETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKL
GADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDGSNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMN
SSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSISTPSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKS
PPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSPTCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGV
AEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFAL
PGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSP
STENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTG
RQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPG
LILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPM

--------------------------------------------------------------
>101159_101159_12_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000556143_DENND4A_chr15_65998562_ENST00000443035_length(transcript)=6927nt_BP=1924nt
AGTGCGCACTACGCCCTTGCTGGCGCCGGGATCCTCCCTCTCTCGCTCCTCCCTTTCTGGGCTGCACCGCTCACGCCTTCCTGTTAGTCC
GAGCTGGGAGAAGTTCACTCCGATCAGCTGATCCCAACTGACAACAGGAGAGGAGGAAGCCCGGGAGGCAACGAAGGAGGAGGGTGGCGG
AGATGGAGATGAGGATGGATCTGCCGGTGTCCTGAGGAATAGCCTCTGCCCCCACTGGCGCCCTGCGGCCCCCCGACGCCGCCTTGCTGC
GGCCGAGCTTCTCAGTGGTATCCCCTGAAATACTGACTTCAGGTCGAATTATATTGAAAAGCTCCTGACCACTTTCTTTCATTACCAAAA
CTTTGTAGCTGATGTCCAACCGATGAACCCACCACCGTGAACCCATCAGACCTCTCTCAGATAGCCATAAAAGACCCTTCCAAGTCAATT
TTGACCACATCTTTGCTTGCACTTTATGGAGGATGAAACCATCAAACCAAATCAACGTTGCTGCTAATACAAGAGTCTTAGAGGCAGCAA
ATTAAAAATTTGAACATTTGTTTGTGAAGAACTATAACAGGACATGAAAGGTGTTCTTTTTTAAAGTGTTCAGAACCCTGTGGAAGTTTC
GTGCAGTCTTCAGACTCAAATCTTCGTCTTCACCCCCGGGGCAAGCTCAGTGACTATTATATGGTGGGTGTGTTTCCTTACCAGCGTGAG
TATGAGTGCCCAGACTTCCCCAGCAGAGAAGGGCCTGAATCCGGGGCTGATGTGCCAGGAAAGTTACGCTTGCAGCGGGACTGATGAAGC
TATCTTTGAGTGTGATGAGTGCTGCAGTCTGCAGTGTCTCCGCTGCGAGGAGGAGCTCCATCGGCAGGAGCGCCTGAGAAACCATGAGCG
GATAAGACTCAAACCTGGCCATGTCCCTTACTGTGACCTCTGCAAGGGTCTCAGTGGGCATTTACCAGGTGTTAGGCAGAGGGCAATAGT
GAGGTGCCAGACCTGCAAAATTAACTTGTGCCTGGAGTGCCAGAAGAGGACTCATTCTGGGGGTAACAAAAGGAGACACCCTGTTACTGT
GTACAATGTCAGTAATCTCCAGGAGTCACTGGAGGCAGAAGAGATGGATGAGGAGACCAAGAGGAAGAAGATGACTGAGAAGGTTGTGAG
TTTCCTCCTAGTAGACGAAAATGAAGAAATTCAGGTAACAAATGAAGAAGACTTTATTAGAAAATTGGACTGCAAACCTGATCAGCATCT
GAAAGTGGTTTCCATTTTTGGAAATACTGGTGATGGAAAGTCTCATACTCTCAACCACACTTTCTTTTATGGTCGTGAAGTCTTTAAAAC
CTCCCCGACCCAGGAGTCCTGCACTGTGGGAGTGTGGGCAGCCTATGACCCAGTTCACAAAGTAGCAGTGATCGATACGGAAGGGCTCCT
GGGGGCCACCGTGAATCTAAGCCAGAGAACACGGCTGCTGCTTAAGGTCCTGGCCATCTCAGACCTCGTCATCTATCGAACTCATGCAGA
CCGGCTGCATAACGACCTCTTCAAATTCCTTGGGGATGCCTCAGAAGCTTATCTGAAGCACTTCACCAAGGAGCTCAAGGCCACCACTGC
TCGCTGTGGCCTGGATGTCCCTTTATCCACACTGGGCCCTGCAGTTATCATCTTCCATGAGACCGTGCACACCCAGCTACTGGGCTCTGA
TCATCCCTCAGAGGTGCCAGAGAAGCTCATCCAGGACCGGTTCCGGAAGCTGGGCCGTTTCCCTGAAGCCTTTAGTTCCATTCACTACAA
GGGAACGAGGACTTACAACCCTCCCACGGACTTTTCTGGGCTTCGGCGTGCTTTGGAGCAGCTACTAGAGAATAACACCACCCGTTCTCC
CCGGCACCCGGGAGTCATCTTCAAAGCCCTGAAGGTGGATATGGACAAGAGCGGTGAAGTACGACTTATAGAACTGGATGAATCTTTCAA
AAGTGAACACACTGTTTTTGTAACACCACCTGAGATCCCCCACCTACCCAATGGTGAAGAACCCCCTTTACAGTACAGCTATAATGGATT
TCCAGTTCTTAGGAACAATTTATTTGAAAGACCTGAAGGATTTCTACAAGCAAAGAAGAACAAATTGCCTTCAAAATCAAGTAGTCCTAA
TAGCCCTTTGCCCATGTTCAGAAGAACAAAACAGGAAATTAAATCAGCCCATAAAATTGCAAAGAGGTACTCTTCCATCCCTCAGATGTG
GTCTAGGTGTCTACTGCGCCACTGTTATGGACTGTGGTTTATTTGTCTCCCAGCTTATGTGAAAGTCTGTCATTCAAAAGTCAGGGCTCT
GAAAACAGCATATGATGTGCTTAAAAAAATGCAGTCAAAGAAGATGGATCCACCTGATGAGGTATGCTACCGCATTCTTATGCAACTCTG
TGGACAATATGATCAGCCAGTGCTTGCAGTTCGAGTGCTTTTTGAAATGCAGAAAGCTGGTATTGACCCCAATGCCATTACTTATGGTTA
TTATAATAAGGCTGTTTTGGAAAGTACCTGGCCTTCAAGAAGTCGTAGTGGCTATTTTCTTTGGACAAAAGTAAGAAATGTTGTTTTAGG
AGTAACACAGTTCAAAAGAGCTTTAAAGAAGCATGCACACTTATCACAAACAACTCTCTCAGATGGCAGTGACCTGGATGCTGTTAGTCA
TGGCAGCATGGATAGTGGTCATGGGACACACACTGTGGAGCAGGCACCTTTTAATACGGGTTTAATCAAAGTATATGCTACTGATGATAG
ATCTAGTACAGGTGGCCAGTCTGATCTTGGATATAATTCATTATCTAAAGATGAAGTTAGAAGAGGGGATACATCTACTGAAGACATTCA
AGAAGAAAAAGATAAAAAAGGGAGTGATTGTAGTTCCTTGTCAGAGAGTGAGAGTACAAAAGGAAGTGCTGATTGCCTTCCTAAGCTCAG
TTATCAAAATTCTTCCAGTATCGTTCGCCTCACTGGTACAAGTAACAACAGTGCTGGTAAAATATCAGGAGAAAGCATGGAAAGCACACC
TGAGCTGCTCTTAATATCATCTCTTGAAGATACAAATGAAACACGAAACATTCAAAGTAGATGCTTCAGGAAAAGACATAAAAGTGACAA
TGAAACTAATTTGCAGCAGCAAGTGGTCTGGGGAAATAGAAACCGTAATCTTAGTGGAGGGGTACTGATGGGATTTATGCTCAATAGAAT
TAACCAGGAAGCAACCCCTGGAGATATAGTTGAAAAATTGGGAGCTGATGCAAAAATTCTTTCAAATGTTATCTCAAAAAGCACGAGACC
AAATACTCTTGATATTGGGAAGCCACCTTTAAGATCAAAAAGAGACAGTCTAGAAAAGGAATCTAGTGATGATGATACACCTTTTGATGG
TTCTAACTATTTGGCAGATAAAGTGGATTCTCCTGTTATTTTTGACTTAGAAGACTTAGACAGTGAAACAGATGTATCAAAAGCAGGATG
TGTTGCTACACAAAATCCCAAGAGGATTCAACGTATGAACAGCAGCTTTTCAGTAAAACCTTTTGAAAAAACTGATGTCGCAACAGGATT
TGATCCCCTCTCTCTTTTGGTTGCTGAGACTGAACAGCAGCAAAAAGAAGAAGAGGAGGAGGATGAAGATGATAGCAAAAGCATTTCAAC
ACCATCTGCTAGGCGTGATTTAGCTGAAGAAATTGTGATGTATATGAATAACATGAGCAGTCCTTTGACAAGTCGTACACCAAGCATTGA
TTTACAACGGGCATGTGATGATAAATTAAATAAGAAAAGTCCACCATTGGTCAAGGCATGCAGAAGATCTAGTCTGCCTCCTAATTCTCC
TAAGCCAGTGAGACTTACCAAATCTAAAAGTTACACAAAAAGTGAGGAGAAACCAAGGGATAGACTTTGGTCTTCTCCAGCCTTCTCACC
TACTTGCCCATTTAGGGAAGAATCTCAGGATACATTAACCCACTCATCACCTTCATTTAACTTAGATACACTACTAGTACCTAAACTAGA
TGTTCTAAGAAACAGTATGTTCACTGCTGGAAAAGGAGTTGCAGAGAAAGCAAGCAAATGGTATTCAAGATTCACCATGTACACCACATC
ATCTAAGGATCAAAGTTCTGATCGTACCAGTCTTTCTTCAGTGGGAGCCCAGGATTCTGAATCTACCTCTTTAACAGATGAAGATGTCTG
CCATGAGTTGGAAGGACCTATCTCCTCTCAAGAGACCAGTGCTACTTCAGGGACTAAGAGAATTGATCTCAGCCGAATAAGCCTGGAAAG
TTCTGCATCCTTGGAAGGATCTCTGTCGAAGTTTGCCTTACCTGGGAAATCAGAAGTGACATCTTCCTTCAACGCGAGTAATACAAATAT
CTTCCAGAACTATGCAATGGAGGTTCTCATCTCAAGTTGCTCTCGGTGTAGAACTTGTGATTGTCTTGTCCATGATGAGGAAATCATGGC
TGGCTGGACAGCAGATGATTCAAATCTCAATACTACATGCCCATTCTGTGGCAATATCTTCTTACCCTTTCTGAATATAGAAATAAGAGA
TTTAAGACGACCTGGAAGATACTTTCTAAAGTCAAGCCCATCAACAGAAAATATGCACTTTCCATCCTCCATTTCAAGTCAGACGAGGCA
GTCTTGCATTTCAACATCAGCCTCTGGTCTTGACACATCTGCTCTCTCTGTTCAAGGGAATTTTGATCTAAATAGCAAATCTAAACTGCA
GGAAAATTTTTGCACCCGAAGTATTCAGATCCCTGCTAATAGATCAAAAACAGCTATGTCTAAATGTCCAATATTTCCAATGGCCAGGAG
TATTAGTACTTCTGGCCCCTTGGATAAGGAAGATACTGGAAGACAGAAGCTCATTTCTACAGGCAGCCTGCCAGCTACTTTACAAGGAGC
TACAGATTCTTTAGGTTTAGAATGGCACCTTCCAAGTCCCGATCCTGTCACTGTTCCGTATCTTAGTCCTTTAGTGGTATGGAAAGAACT
TGAAAGCTTATTGGAAAATGAAGGTGATCATGCAATAACAGTAGCAGACTTTGTGGACCATCATCCAATTGTTTTTTGGAACCTGGTATG
GTATTTCAGACGTCTTGACTTGCCCAGTAACTTACCTGGATTGATTCTTTCTTCTGAGCACTGTAACAAGTATTCAAAGATTCCCCGCCA
CTGTATGTCTGAAGATAGCAAATATGTTTTAATACAAATGTTATGGGACAATATGAAGTTACATCAGGATCCGGGACAGCCCTTGTACAT
TCTCTGGAATGCACACACCCAAAAATATCCAATGGTCCATTTATTGCAAAAAAGTGATAACTCATTTAACCAGGAACTGTTGAAAAGTAT
GGTAAAAAGCATTAAAATGAATGATGTCTATGGACCAATGAGTCAGATTTTAGAGACACTGAATAAGTGTCCACATTTTAAAAGACAGAG
GAGTTTATACAGAGAAATACTATTTCTCTCACTTGTGGCACTGGGAAGAGAAAACATTGATATAGATGCTTTTGATAAAGAGTACAAGAT
GGCATACGATCGTCTCACACCTAGTCAAGTCAAGAGTACACACAACTGTGATAGACCACCAAGTACAGGGGTGATGGAATGTCGAAAAAC
CTTTGGAGAACCTTATCTTTAAGATGTATTTGTATGTGTAAACATTCAATGTATATTGTATAGTCAGTGTATAAAATAACACTTTTAGAC
TCTAAATATTTTTTCTTCAATTTTTGAAAATACAATTTGTAAATGGTTCAAAAGACTCAGACAGCTTATGTACAGAATGTTTGAAGAAGA
GAATAGTGACAAGTGGGGAGAAAGCCACTTTGTTTCTCATTTCTTTTTTCTTCTTCTTTAACTCCCCTGTAATAGGAAATAAAGTATTTT
TGTGATGAGGAAATCCCTAAACAAAATTAGTTGCCATAAAATATGACAACTGCTTTATGGTTTCTTTTGGAAGAGACAGATTGAAAAATC
ATGAATGGAATCTAAACAGAAATGTCAGATGAACGTATTTCCTGTTTTCATAGACTATTCAAATGTTTTGACCATGAAGTTGTATTATAC
ATATTTTAAATTGTTTATAGTAAGTTGATATTTTTTTAATTTTTAAATTTAATATAGCAAACTTAAAATGAATTTAAACTTAAGCAAGCA
AGCGTGTATTTTCCTTGTCTGCTGCTATTTGAAGTAATTAGTACAGCTGCAGATCTCTCTGTGTATATCTATCTATATATATATTTTTTA
TTACTTGGGAGAATGAATTTTAAAATGTCAGTGCTAGTGTCAAGTGTTGTCCTAGGATTGCATGTTAGTACCCCTAAGCCTGAGTGTGGG
GAGTGAGTTATGCAAGGGTAGCGTGCACTGCCCAGACTGACTCATGGAGCCTTGTGCAAGGAGAGCCAGAGAGGTTCACTATACCATGAC
TCCAAAATTGTCTCTATTGCTAATAGATACGTATAGTATACAGGGAAAACAGCTTATAAATCCAAATATCAATTTAAATTTTAATATTCT
ACATGAAAACTTACATTGGGAAATATGCAGACAAGTGATTATATTCCAAATTTTACCCTTATTTTAATATCTAAAATATTGGGTATGATG
CAAATTATACTATAGAATATTTATCTGAAATATGACTTACTGGGGTATTCTGTTAATACTATATATAAATATTCAGAATTTTTTTCAAAA
GTAGAAAAATTCCCCTCTAAAAGTACAGCCAGATAGATTTTCATCCATATTGAGGAACTTAGCTTTTTCAACAAGCTTCAGAATCTGAAG

>101159_101159_12_ZFYVE1-DENND4A_ZFYVE1_chr14_73459851_ENST00000556143_DENND4A_chr15_65998562_ENST00000443035_length(amino acids)=1656AA_BP=397
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIV
RCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHAD
RLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGF
PVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRAL
KTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLG
VTQFKRALKKHAHLSQTTLSDGSDLDAVSHGSMDSGHGTHTVEQAPFNTGLIKVYATDDRSSTGGQSDLGYNSLSKDEVRRGDTSTEDIQ
EEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGTSNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDN
ETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKLGADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDG
SNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMNSSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSIST
PSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKSPPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSP
TCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVC
HELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFALPGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMA
GWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQ
ENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKEL
ESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYI
LWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKM

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZFYVE1-DENND4A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZFYVE1-DENND4A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZFYVE1-DENND4A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource