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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:BRAF-CIITA (FusionGDB2 ID:10118)

Fusion Gene Summary for BRAF-CIITA

Fusion gene summary

Fusion gene information	Fusion gene name: BRAF-CIITA
	Fusion gene ID: 10118
		Hgene	Tgene
	Gene symbol	BRAF	CIITA
	Gene ID	673	4261
	Gene name	B-Raf proto-oncogene, serine/threonine kinase	class II major histocompatibility complex transactivator
	Synonyms	B-RAF1\|B-raf\|BRAF1\|NS7\|RAFB1	C2TA\|CIITAIV\|MHC2TA\|NLRA
	Cytomap	7q34	16p13.13
	Type of gene	protein-coding	protein-coding
	Description	serine/threonine-protein kinase B-raf94 kDa B-raf proteinB-Raf proto-oncogene serine/threonine-protein kinase (p94)B-Raf serine/threonine-proteinmurine sarcoma viral (v-raf) oncogene homolog B1proto-oncogene B-Rafv-raf murine sarcoma viral oncogene	MHC class II transactivatorMHC class II transactivator type IMHC class II transactivator type IIINLR family, acid domain containingnucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing
	Modification date	20200329	20200320
	UniProtAcc	P15056	P33076
	Ensembl transtripts involved in fusion gene	ENST00000288602,	ENST00000537380, ENST00000324288, ENST00000381835,
Fusion gene scores	* DoF score	28 X 21 X 11=6468	7 X 7 X 6=294
	# samples	32	7
	** MAII score	log2(32/6468*10)=-4.3371758685863 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(7/294*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: BRAF [Title/Abstract] AND CIITA [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	BRAF(140487348)-CIITA(10995371), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	BRAF	GO:0000186	activation of MAPKK activity	29433126
Hgene	BRAF	GO:0006468	protein phosphorylation	17563371
Hgene	BRAF	GO:0010828	positive regulation of glucose transmembrane transport	23010278
Hgene	BRAF	GO:0033138	positive regulation of peptidyl-serine phosphorylation	19667065
Hgene	BRAF	GO:0043066	negative regulation of apoptotic process	19667065
Hgene	BRAF	GO:0070374	positive regulation of ERK1 and ERK2 cascade	22065586
Hgene	BRAF	GO:0071277	cellular response to calcium ion	18567582
Hgene	BRAF	GO:0090150	establishment of protein localization to membrane	23010278
Tgene	CIITA	GO:0034341	response to interferon-gamma	19041327
Tgene	CIITA	GO:0045345	positive regulation of MHC class I biosynthetic process	20639463
Tgene	CIITA	GO:0045892	negative regulation of transcription, DNA-templated	19041327
Tgene	CIITA	GO:0045893	positive regulation of transcription, DNA-templated	19041327
Tgene	CIITA	GO:0045944	positive regulation of transcription by RNA polymerase II	20639463
Tgene	CIITA	GO:0046677	response to antibiotic	107465

Fusion gene breakpoints across BRAF (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CIITA (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	THCA	TCGA-EM-A3AQ-01A	BRAF	chr7	140487348	-	CIITA	chr16	10995371	+

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Fusion Gene ORF analysis for BRAF-CIITA

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000288602	ENST00000537380	BRAF	chr7	140487348	-	CIITA	chr16	10995371	+
In-frame	ENST00000288602	ENST00000324288	BRAF	chr7	140487348	-	CIITA	chr16	10995371	+
In-frame	ENST00000288602	ENST00000381835	BRAF	chr7	140487348	-	CIITA	chr16	10995371	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

ENST00000288602

BRAF

chr7

140487348

ENST00000324288

CIITA

chr16

10995371

10107

1238

4194

1377

ENST00000288602

BRAF

chr7

140487348

ENST00000381835

CIITA

chr16

10995371

3025

1238

2442

793

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000288602	ENST00000324288	BRAF	chr7	140487348	-	CIITA	chr16	10995371	+	0.001094813	0.9989052
ENST00000288602	ENST00000381835	BRAF	chr7	140487348	-	CIITA	chr16	10995371	+	0.006972153	0.99302787

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Fusion Genomic Features for BRAF-CIITA

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
BRAF	chr7	140487347	-	CIITA	chr16	10995370	+	3.07E-05	0.99996924
BRAF	chr7	140487347	-	CIITA	chr16	10995370	+	3.07E-05	0.99996924

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for BRAF-CIITA

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:140487348/chr16:10995371)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
BRAF P15056	CIITA P33076
FUNCTION: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:21441910, PubMed:29433126). May play a role in the postsynaptic responses of hippocampal neurons (PubMed:1508179). {ECO:0000269\|PubMed:1508179, ECO:0000269\|PubMed:21441910, ECO:0000269\|PubMed:29433126, ECO:0000305}.	FUNCTION: Essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. May act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter. Also mediates enhanced MHC class I transcription; the promoter element requirements for CIITA-mediated transcription are distinct from those of constitutive MHC class I transcription, and CIITA can functionally replace TAF1 at these genes. Activates CD74 transcription (PubMed:32855215). Exhibits intrinsic GTP-stimulated acetyltransferase activity. Exhibits serine/threonine protein kinase activity: can phosphorylate the TFIID component TAF7, the RAP74 subunit of the general transcription factor TFIIF, histone H2B at 'Ser-37' and other histones (in vitro). Has antiviral activity against Ebola virus and coronaviruses, including SARS-CoV-2. Induces resistance by up-regulation of the p41 isoform of CD74, which blocks cathepsin-mediated cleavage of viral glycoproteins, thereby preventing viral fusion (PubMed:32855215). {ECO:0000269\|PubMed:11172716, ECO:0000269\|PubMed:16600381, ECO:0000269\|PubMed:17493635, ECO:0000269\|PubMed:24036077, ECO:0000269\|PubMed:32855215}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

BRAF

chr7:140487348

chr16:10995371

ENST00000288602

122_129

392

767.0

Compositional bias

Note=Poly-Ser

Hgene

BRAF

chr7:140487348

chr16:10995371

ENST00000288602

6_11

392

767.0

Compositional bias

Note=Poly-Gly

Hgene

BRAF

chr7:140487348

chr16:10995371

ENST00000288602

155_227

392

767.0

Domain

RBD

Hgene

BRAF

chr7:140487348

chr16:10995371

ENST00000288602

234_280

392

767.0

Zinc finger

Phorbol-ester/DAG-type

Tgene

CIITA

chr7:140487348

chr16:10995371

ENST00000324288

414_724

145

3032.6666666666665

Domain

NACHT

Tgene

CIITA

chr7:140487348

chr16:10995371

ENST00000324288

420_427

145

3032.6666666666665

Nucleotide binding

Note=GTP

Tgene

CIITA

chr7:140487348

chr16:10995371

ENST00000324288

1016_1037

145

3032.6666666666665

Repeat

Note=LRR 2

Tgene

CIITA

chr7:140487348

chr16:10995371

ENST00000324288

1045_1066

145

3032.6666666666665

Repeat

Note=LRR 3

Tgene

CIITA

chr7:140487348

chr16:10995371

ENST00000324288

1073_1093

145

3032.6666666666665

Repeat

Note=LRR 4

Tgene

CIITA

chr7:140487348

chr16:10995371

ENST00000324288

985_1008

145

3032.6666666666665

Repeat

Note=LRR 1

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

BRAF

chr7:140487348

chr16:10995371

ENST00000288602

428_432

392

767.0

Compositional bias

Note=Poly-Ser

Hgene

BRAF

chr7:140487348

chr16:10995371

ENST00000288602

457_717

392

767.0

Domain

Protein kinase

Hgene

BRAF

chr7:140487348

chr16:10995371

ENST00000288602

463_471

392

767.0

Nucleotide binding

ATP

Tgene

CIITA

chr7:140487348

chr16:10995371

ENST00000324288

52_137

145

3032.6666666666665

Compositional bias

Note=Asp/Glu-rich (acidic)

Tgene

CIITA

chr7:140487348

chr16:10995371

ENST00000324288

94_132

145

3032.6666666666665

Region

Note=Required for acetyltransferase activity

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Fusion Gene Sequence for BRAF-CIITA

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>10118_10118_1_BRAF-CIITA_BRAF_chr7_140487348_ENST00000288602_CIITA_chr16_10995371_ENST00000324288_length(transcript)=10107nt_BP=1238nt
CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG
CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA
CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG
GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT
GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT
GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT
CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT
AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA
AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT
TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG
TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC
TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCAT
TCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCA
TATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGCCTTCCCAGAGGAGCTTCCGGC
AGACCTGAAGCACTGGAAGCCAGCTGAGCCCCCCACTGTGGTGACTGGCAGTCTCCTAGTGAGACCAGTGAGCGACTGCTCCACCCTGCC
CTGCCTGCCACTGCCTGCGCTGTTCAACCAGGAGCCAGCCTCCGGCCAGATGCGCCTGGAGAAAACCGACCAGATTCCCATGCCTTTCTC
CAGTTCCTCGTTGAGCTGCCTGAATCTCCCTGAGGGACCCATCCAGTTTGTCCCCACCATCTCCACTCTGCCCCATGGGCTCTGGCAAAT
CTCTGAGGCTGGAACAGGGGTCTCCAGTATATTCATCTACCATGGTGAGGTGCCCCAGGCCAGCCAAGTACCCCCTCCCAGTGGATTCAC
TGTCCACGGCCTCCCAACATCTCCAGACCGGCCAGGCTCCACCAGCCCCTTCGCTCCATCAGCCACTGACCTGCCCAGCATGCCTGAACC
TGCCCTGACCTCCCGAGCAAACATGACAGAGCACAAGACGTCCCCCACCCAATGCCCGGCAGCTGGAGAGGTCTCCAACAAGCTTCCAAA
ATGGCCTGAGCCGGTGGAGCAGTTCTACCGCTCACTGCAGGACACGTATGGTGCCGAGCCCGCAGGCCCGGATGGCATCCTAGTGGAGGT
GGATCTGGTGCAGGCCAGGCTGGAGAGGAGCAGCAGCAAGAGCCTGGAGCGGGAACTGGCCACCCCGGACTGGGCAGAACGGCAGCTGGC
CCAAGGAGGCCTGGCTGAGGTGCTGTTGGCTGCCAAGGAGCACCGGCGGCCGCGTGAGACACGAGTGATTGCTGTGCTGGGCAAAGCTGG
TCAGGGCAAGAGCTATTGGGCTGGGGCAGTGAGCCGGGCCTGGGCTTGTGGCCGGCTTCCCCAGTACGACTTTGTCTTCTCTGTCCCCTG
CCATTGCTTGAACCGTCCGGGGGATGCCTATGGCCTGCAGGATCTGCTCTTCTCCCTGGGCCCACAGCCACTCGTGGCGGCCGATGAGGT
TTTCAGCCACATCTTGAAGAGACCTGACCGCGTTCTGCTCATCCTAGACGGCTTCGAGGAGCTGGAAGCGCAAGATGGCTTCCTGCACAG
CACGTGCGGACCGGCACCGGCGGAGCCCTGCTCCCTCCGGGGGCTGCTGGCCGGCCTTTTCCAGAAGAAGCTGCTCCGAGGTTGCACCCT
CCTCCTCACAGCCCGGCCCCGGGGCCGCCTGGTCCAGAGCCTGAGCAAGGCCGACGCCCTATTTGAGCTGTCCGGCTTCTCCATGGAGCA
GGCCCAGGCATACGTGATGCGCTACTTTGAGAGCTCAGGGATGACAGAGCACCAAGACAGAGCCCTGACGCTCCTCCGGGACCGGCCACT
TCTTCTCAGTCACAGCCACAGCCCTACTTTGTGCCGGGCAGTGTGCCAGCTCTCAGAGGCCCTGCTGGAGCTTGGGGAGGACGCCAAGCT
GCCCTCCACGCTCACGGGACTCTATGTCGGCCTGCTGGGCCGTGCAGCCCTCGACAGCCCCCCCGGGGCCCTGGCAGAGCTGGCCAAGCT
GGCCTGGGAGCTGGGCCGCAGACATCAAAGTACCCTACAGGAGGACCAGTTCCCATCCGCAGACGTGAGGACCTGGGCGATGGCCAAAGG
CTTAGTCCAACACCCACCGCGGGCCGCAGAGTCCGAGCTGGCCTTCCCCAGCTTCCTCCTGCAATGCTTCCTGGGGGCCCTGTGGCTGGC
TCTGAGTGGCGAAATCAAGGACAAGGAGCTCCCGCAGTACCTAGCATTGACCCCAAGGAAGAAGAGGCCCTATGACAACTGGCTGGAGGG
CGTGCCACGCTTTCTGGCTGGGCTGATCTTCCAGCCTCCCGCCCGCTGCCTGGGAGCCCTACTCGGGCCATCGGCGGCTGCCTCGGTGGA
CAGGAAGCAGAAGGTGCTTGCGAGGTACCTGAAGCGGCTGCAGCCGGGGACACTGCGGGCGCGGCAGCTGCTGGAGCTGCTGCACTGCGC
CCACGAGGCCGAGGAGGCTGGAATTTGGCAGCACGTGGTACAGGAGCTCCCCGGCCGCCTCTCTTTTCTGGGCACCCGCCTCACGCCTCC
TGATGCACATGTACTGGGCAAGGCCTTGGAGGCGGCGGGCCAAGACTTCTCCCTGGACCTCCGCAGCACTGGCATTTGCCCCTCTGGATT
GGGGAGCCTCGTGGGACTCAGCTGTGTCACCCGTTTCAGGGCTGCCTTGAGCGACACGGTGGCGCTGTGGGAGTCCCTGCAGCAGCATGG
GGAGACCAAGCTACTTCAGGCAGCAGAGGAGAAGTTCACCATCGAGCCTTTCAAAGCCAAGTCCCTGAAGGATGTGGAAGACCTGGGAAA
GCTTGTGCAGACTCAGAGGACGAGAAGTTCCTCGGAAGACACAGCTGGGGAGCTCCCTGCTGTTCGGGACCTAAAGAAACTGGAGTTTGC
GCTGGGCCCTGTCTCAGGCCCCCAGGCTTTCCCCAAACTGGTGCGGATCCTCACGGCCTTTTCCTCCCTGCAGCATCTGGACCTGGATGC
GCTGAGTGAGAACAAGATCGGGGACGAGGGTGTCTCGCAGCTCTCAGCCACCTTCCCCCAGCTGAAGTCCTTGGAAACCCTCAATCTGTC
CCAGAACAACATCACTGACCTGGGTGCCTACAAACTCGCCGAGGCCCTGCCTTCGCTCGCTGCATCCCTGCTCAGGCTAAGCTTGTACAA
TAACTGCATCTGCGACGTGGGAGCCGAGAGCTTGGCTCGTGTGCTTCCGGACATGGTGTCCCTCCGGGTGATGGACGTCCAGTACAACAA
GTTCACGGCTGCCGGGGCCCAGCAGCTCGCTGCCAGCCTTCGGAGGTGTCCTCATGTGGAGACGCTGGCGATGTGGACGCCCACCATCCC
ATTCAGTGTCCAGGAACACCTGCAACAACAGGATTCACGGATCAGCCTGAGATGATCCCAGCTGTGCTCTGGACAGGCATGTTCTCTGAG
GACACTAACCACGCTGGACCTTGAACTGGGTACTTGTGGACACAGCTCTTCTCCAGGCTGTATCCCATGAGCCTCAGCATCCTGGCACCC
GGCCCCTGCTGGTTCAGGGTTGGCCCCTGCCCGGCTGCGGAATGAACCACATCTTGCTCTGCTGACAGACACAGGCCCGGCTCCAGGCTC
CTTTAGCGCCCAGTTGGGTGGATGCCTGGTGGCAGCTGCGGTCCACCCAGGAGCCCCGAGGCCTTCTCTGAAGGACATTGCGGACAGCCA
CGGCCAGGCCAGAGGGAGTGACAGAGGCAGCCCCATTCTGCCTGCCCAGGCCCCTGCCACCCTGGGGAGAAAGTACTTCTTTTTTTTTAT
TTTTAGACAGAGTCTCACTGTTGCCCAGGCTGGCGTGCAGTGGTGCGATCTGGGTTCACTGCAACCTCCGCCTCTTGGGTTCAAGCGATT
CTTCTGCTTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCACCATCATGTCTGGCTAATTTTTCATTTTTAGTAGAGACAGGGTTTTG
CCATGTTGGCCAGGCTGGTCTCAAACTCTTGACCTCAGGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAAGCGTGAGCCA
CTGCACCGGGCCACAGAGAAAGTACTTCTCCACCCTGCTCTCCGACCAGACACCTTGACAGGGCACACCGGGCACTCAGAAGACACTGAT
GGGCAACCCCCAGCCTGCTAATTCCCCAGATTGCAACAGGCTGGGCTTCAGTGGCAGCTGCTTTTGTCTATGGGACTCAATGCACTGACA
TTGTTGGCCAAAGCCAAAGCTAGGCCTGGCCAGATGCACCAGCCCTTAGCAGGGAAACAGCTAATGGGACACTAATGGGGCGGTGAGAGG
GGAACAGACTGGAAGCACAGCTTCATTTCCTGTGTCTTTTTTCACTACATTATAAATGTCTCTTTAATGTCACAGGCAGGTCCAGGGTTT
GAGTTCATACCCTGTTACCATTTTGGGGTACCCACTGCTCTGGTTATCTAATATGTAACAAGCCACCCCAAATCATAGTGGCTTAAAACA
ACACTCACATTTATTCTGCTCACATATCTGTCATTTGAGCAGGGCTCAGCGGGGACAGCTCCTTCTGTCCTACTCTGTGTCAGGTGGGGC
AGCTTGAGGGTTGGGCTGGTGTCACCTGAAGACTCATTCTTCTGTACGTCTGACAGGCAATGCTGGCTGTTGGCTGGGGGCCTCAGTGCC
ACTACGGAATAGTTGGCTAGGACCCCTCCATGTGGGCTAGTTGGGCTTCCTCATAGTATGGTGGCTGGGTTGGAGGGTGTCCCAAAAAGA
AAGGAGGGGATAGAGAGAGACCACTTTTCATAACCTAGCCTTAGAAGTCACACAGTATTACTTCTGCTACATATATATGTTTTAAGAGGC
AGGGTCTCACTCTGTCGCCCAGTCTGGAATGCAGTGGTATGATCACGGCTCACTGCAGCCTCAACCTCCTGGGCTAAGTGATCCTCCCAC
CTCAGCCTCCCGAATAGCTGGGACTACAGGTGTGAGTCACCAAGCCCAGTTAATCTTTAGTTTTATTTTTGTAGAGCCAGGGTCTCACTA
TGTTGCCCAGGCAGGTCTTGAACTCCTGGCCTCAAGTGATTCTCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAACCACCA
CACCCAGCCCACTTCTGCCATATTCTGTTGGCCAGTGTGACAAGGATTGCTACTGTCCTACCCACCCTCCTTTCACCACATGTGCACATG
CACGTGTGTGCACGTACACACACATACACACACACGCGTGCACACACCAGAGCCCACCTTGGCTCAAGTCCTCTTTTCTGAGAGGACTTT
TCTTTGTGGCTTCCTAAAATTCAGTGGAAAATTAATTGTTTGGGGATGAGAAAGGTTGAAGCACCAAAAGCTTACCAAGGGGAATGTTTG
CCTCTGCCTCTGACACACAGCTCTGTCCTGGGAGTGAGCTGGTTTTTAGCGGAGACGGAGTCCCACCTTGGCTGCAGGGAGTCCGAAAGG
GACTTGGAAGCTCCGCTTTCTACCCAGCGAGCTGCCGGCACGACTGTTGCTTTTCACTCGGGCATAGTCTGCTCAGAAGCCCCAATTCAA
GACATCTTAGCTTACTCCTGGTGGCAGTGGGAGCTGCCTGTTCAGCTCCAGCTCACCAGCCCCAGTGCCCACAGGATCAGTCTGATTCCC
AAGCTCTGCTCCTCTCCCCAGCAAGTGAGAGCTGGGTGTCAAGAGGGTCTGAGGAATCCAGACCCGGCTGCGTGGTTGATGATCTTTGCA
GACAGGCAAGCACCTCCTGCCTCGAACTGGCTGCAAAGGGTATCAGGTGCTGCCATCCAGGTTCAGCTTGTAAATAGCTCAGGTGTCACC
CTGCAAGGGATCCCTGCACTTGCAGACTCTACAGAGGCCATGGGCCTCCTGTGTGTGCGCCTACAGGAGTGAGCACTAAGGTGTGCTCTG
ATCATCCACTGTGCCATGTGCCAGGTTTTTGGTCTGACCCACTGCTTTTGGTCTGTGTGATGATGAAATGAGGTCAGAGCCTGCAGTTAT
TAACACTAACGATTTGTTAATGATAGCTACTGTTTATTATTTTATTTAATTTTTTTGAGACAGAGTTTTCACTCTTATTGCCCACGCTGG
AGTGCAGTGGCATGATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCAATTCTCCCACCTCAGCCTCCCAAGTAGCTGGGATTA
CAGGCATGCACCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAGGCTGGTAATCTGCCTGCCT
TGGCCTCCCAAAGTGCTGGGATTACAGGGGTGAGCCACCGCACCCGGCCACTACTGTTTATTTAATGAGCAGATACATGCAAAGCCCTTA
TCACAGTGCAAGGGAAATTCAAAGCGCTCAGAAAGTATTAGCTCAATAAGTGATGACTGTGTGCCAGACACTGTGCTAAACTCCTACTCA
AGAGGGATAAGAGTCTAGGGGCAAGTGGCAGAGACTCTAGAACGAGATTGCCTGGGCTCAACGCCCACCTCACCACTTACTTATGCAAGC
TAGTTCTCTGTGCCTCAGTCTCCTCATTTGTAAAATGGGCATAACCACAGCACCTTCTTTATAGGATTATGTGAAGGTGTGGTGAGCTAA
TACGTTAAGAATTGGAGCTCAATAACATGTTGGCTGTCATTATTACATATATCTGTGTTTCATTCTTGCCTCTGGCTGGAATGTTCTTCC
CAGCTCTCCATATGGCTGATTTCTCATCCTTCGGGACTTGCCCCATTCTCCAACCCCATCACTAGTTTTATCTTTTTCACTTATTTATGC
AGTCTGCTCTTGTCCTAGGACATGAGCTCCAGGAGGGCGGGAAACATCTCGCTTTGTACACTGCTGTGCCCTCTGTACCCAGCAAGGCGC
CTGTGTATAATAGGTGCTCAATAACATAAAATGAACAAATAATCCTCACCTAACGGTTTCATTCATTCTGCAAATACATACTGACAGCAC
AGTCATGAATAAGATGTTCCTGCCCTGGTGAGTCTTATATTTTAGCAAATTAAAAAAACTCTTTGGACAGGGCTGCCAGGTGAGGTTGGC
CAGTCTGTACACTGCACAAAGGCACCTGGGACAAGGGGGAACATGGGGGCTGCAAACCAGTCTGGGTTCTGCTTGCCAAACTGGGAGTCC
TGGTGTGGAGCCTTTTAACCCAGAGGGGCATCTTTTCGTAGTTAACGCACAGTCATCGTAAGATGTGGATAAATTACTGTCTCCGTGTCA
CAGATCTAAGTGATACTTATAGTCACACTCCTATAAAGGAATGGACTTCTGACTTCTTTGGAGGACCTCTCTGCAGGGACAGGCACAGTG
TGCCGGAAGTGCCCCTGAACCCCATTTGTCAGGTGGTAAAGCGCTGCTCGGAGGAATCAGGGCATGATAGTGCAATTCCATGTCCAGTGG
ATTGTAAGTCCACGCACCTTCCAAATGGTCACTCTTCCTCGCAGGCCTCTCTCTGCATACAAATGTCTCCCTCCTGACGCTCACCTTTTT
CCCTGGGGCTCTCAAATGTCTTCTTTTCAGATTTCGTAGCTTTTCTTTCTTTAGCATCACTTGAGGGCAAGTGGTGCTCCAACTGTCTCC
CCCCAGAGTTCTGCCGCCTGTACTCTCCCACACCTCAGTCTCCTCGCCTGTAGAAAGGGGTCAATCGTTTGAACCCTGCTTCACTTGGTG
TGTATGTGAAGGTGCTTTGAAATCAAGTGCTCTGCAAACTGGAGAGAATTACTGCTTGTATTCCGTGAAACTACAAGCTCCCAATTCCAC
TCATTTAATCCCTCTCTTGCTCTGTTGCCCAGGCTGGAATGCAGTGGCATGATCTCAACTCACTGCAACCTCTGCCTCCCTGGTTTCAAG
CAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTATAAGTGTGCGCCACTATGCCTGGCTAATTTTTTTGTATTTTTAGTAGAGATG
GGGTTTCACCGTGGTGGCCAGGCTGGTCTCGAACTCCTAACCTCAAGTGATCTGCCCGCCTCGGCCTTCCAAAGTGCTGGGATTACAGGC
ATGAGCCACCATGCCAAGCCCTTCCCCCCTATCTTTAATGAAGGTCTACCATGTGCCTGACACAGGGGATACCCACCCCCACTTCTATGG
GATTCAGGCCTGGTTTCCAGCTTGGCCTTCAGGCTTTTCCCACCACACCCCAAATGCTGTCCCTGGCTTGTGGAGTGGGGCAGGGGGCCA
GCCTGGGACTTTCACGCCAGCCCGACTGGGGCAGACTCTCTCAACCCCACTGGATCTTCTGCTGTTTGTCAGCCACAAGGTTCTGCCTAG
AACTCCTTTCCCGAATCTCAAAGTTAAAAAAAAAGGCAGGGCCCCAGGGGTTGGAGTTGCATACATTTTTTTTTAATCCAAAGAAGTAAG
CCTCCTAAGTATTGCTTAGACAGGTTTATCAGAATTAAGTAGGCACAACACTCATACTTTCAGAAAAGCATTTCCAGCCAGGGGAGTAAC
GTGGCACTCACCAGCATGATGTCTGTTTTGCCAACTTGCTGAAGAACGAGTAACCTGAAATGAAGGAGCGAGAATCCCACCCTCAGCCCC
CCAACAGCTTCCTCAGCTTCTTTTTCTTCTGAGTCACCCCTGAAACAGTCGCTGCATCTAAGACCAGCCTCGGGCTAAACCCAGCTGGCC
TGAAGGCTCAACTCACATCAAACGGAGCTGGGAGTCGCTTTTGCGTGTGTCCGCAGTTTGAAGTGTCCTCTCCGAAGGTGAAGTGGGGGA
AGCAGGTGCGCTCCGGGATGAAGTGCAGGGAGGCAAACTCTGGCTGGGTTCCTGTAAACATCCATCGCAGCTGCAAATAATCAGAAGCCA
AGGCCAGGCCATCGATTTGACACTGCAGGCAGATGAGGTCTTGGGATGCCTCTTGCGTTCCCCCTTCTGTGGGAGCAGGTGCCTTCCCAA
CCTCAGCACTCAGTCCCAATCTCTCTTCCACTCTCCTGGGTTCAAACAGGAACCTCTCTGTTGGCACGAAGCTTTTGAGGGGAGCAGGTC
TAACAAGAAGGAAAAAGGGGGGTTATTAGCACGGAAGCCCCACCCTGCCACCAGGTTGGCTGGGGACAGGGACCAATCCACCAGGCTCGG
GAGGCTTGGGGTGGGGCAGGGAAGTCTTCCTCCATCCCTCAAATTTAGGGAACCACTGGGAGCCCCAGACTCAGGCTGAAAATGTCTTTC

>10118_10118_1_BRAF-CIITA_BRAF_chr7_140487348_ENST00000288602_CIITA_chr16_10995371_ENST00000324288_length(amino acids)=1377AA_BP=392
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD
ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ
RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQR
DRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGAFPEELPADLKHWKPAEPPTVVTGSLLVRPVSDCSTLPCLPLPALFNQEPASGQMRLE
KTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPS
ATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGILVEVDLVQARLERSSSKSLERELA
TPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQDLLFSLG
PQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADAL
FELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGRAALDSP
PGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRK
KRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPGRL
SFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESLQQHGETKLLQAAEEKFTIEPFKAK
SLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQ
LKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVE

--------------------------------------------------------------
>10118_10118_2_BRAF-CIITA_BRAF_chr7_140487348_ENST00000288602_CIITA_chr16_10995371_ENST00000381835_length(transcript)=3025nt_BP=1238nt
CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG
CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA
CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG
GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT
GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT
GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT
CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT
AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA
AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT
TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG
TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC
TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCAT
TCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCA
TATAAACACAATAGAACCTGTCAATATTGATGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGCCTTCCCAGAGGAGCTTCCGGC
AGACCTGAAGCACTGGAAGCCAGTGCCTTTCTCCAGTTCCTCGTTGAGCTGCCTGAATCTCCCTGAGGGACCCATCCAGTTTGTCCCCAC
CATCTCCACTCTGCCCCATGGGCTCTGGCAAATCTCTGAGGCTGGAACAGGGGTCTCCAGTATATTCATCTACCATGGTGAGGTGCCCCA
GGCCAGCCAAGTACCCCCTCCCAGTGGATTCACTGTCCACGGCCTCCCAACATCTCCAGACCGGCCAGGCTCCACCAGCCCCTTCGCTCC
ATCAGCCACTGACCTGCCCAGCATGCCTGAACCTGCCCTGACCTCCCGAGCAAACATGACAGAGCACAAGACGTCCCCCACCCAATGCCC
GGCAGCTGGAGAGGTCTCCAACAAGCTTCCAAAATGGCCTGGTCTAGCCTGGTCACCGTGCCTGGGTCTGAGGCCCTCCCTCCACAGGGC
TGCCTTGAGCGACACGGTGGCGCTGTGGGAGTCCCTGCAGCAGCATGGGGAGACCAAGCTACTTCAGGCAGCAGAGGAGAAGTTCACCAT
CGAGCCTTTCAAAGCCAAGTCCCTGAAGGATGTGGAAGACCTGGGAAAGCTTGTGCAGACTCAGAGGACGAGAAGTTCCTCGGAAGACAC
AGCTGGGGAGCTCCCTGCTGTTCGGGACCTAAAGAAACTGGAGTTTGCGCTGGGCCCTGTCTCAGGCCCCCAGGCTTTCCCCAAACTGGT
GCGGATCCTCACGGCCTTTTCCTCCCTGCAGCATCTGGACCTGGATGCGCTGAGTGAGAACAAGATCGGGGACGAGGGTGTCTCGCAGCT
CTCAGCCACCTTCCCCCAGCTGAAGTCCTTGGAAACCCTCAATCTGTCCCAGAACAACATCACTGACCTGGGTGCCTACAAACTCGCCGA
GGCCCTGCCTTCGCTCGCTGCATCCCTGCTCAGGCTAAGCTTGTACAATAACTGCATCTGCGACGTGGGAGCCGAGAGCTTGGCTCGTGT
GCTTCCGGACATGGTGTCCCTCCGGGTGATGGACGTCCAGTACAACAAGTTCACGGCTGCCGGGGCCCAGCAGCTCGCTGCCAGCCTTCG
GAGGTGTCCTCATGTGGAGACGCTGGCGATGTGGACGCCCACCATCCCATTCAGTGTCCAGGAACACCTGCAACAACAGGATTCACGGAT
CAGCCTGAGATGATCCCAGCTGTGCTCTGGACAGGCATGTTCTCTGAGGACACTAACCACGCTGGACCTTGAACTGGGTACTTGTGGACA
CAGCTCTTCTCCAGGCTGTATCCCATGAGCCTCAGCATCCTGGCACCCGGCCCCTGCTGGTTCAGGGTTGGCCCCTGCCCGGCTGCGGAA
TGAACCACATCTTGCTCTGCTGACAGACACAGGCCCGGCTCCAGGCTCCTTTAGCGCCCAGTTGGGTGGATGCCTGGTGGCAGCTGCGGT
CCACCCAGGAGCCCCGAGGCCTTCTCTGAAGGACATTGCGGACAGCCACGGCCAGGCCAGAGGGAGTGACAGAGGCAGCCCCATTCTGCC
TGCCCAGGCCCCTGCCACCCTGGGGAGAAAGTACTTCTTTTTTTTTATTTTTAGACAGAGTCTCACTGTTGCCCAGGCTGGCGTGCAGTG
GTGCGATCTGGGTTCACTGCAACCTCCGCCTCTTGGGTTCAAGCGATTCTTCTGCTTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCC

>10118_10118_2_BRAF-CIITA_BRAF_chr7_140487348_ENST00000288602_CIITA_chr16_10995371_ENST00000381835_length(amino acids)=793AA_BP=392
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD
ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ
RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQR
DRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGAFPEELPADLKHWKPVPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISEAGTGVSS
IFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPGLAWSPC
LGLRPSLHRAALSDTVALWESLQQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPV
SGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCIC

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for BRAF-CIITA

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for BRAF-CIITA

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for BRAF-CIITA

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source