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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZMYND8-GNAI3 (FusionGDB2 ID:101403)

Fusion Gene Summary for ZMYND8-GNAI3

check button Fusion gene summary
Fusion gene informationFusion gene name: ZMYND8-GNAI3
Fusion gene ID: 101403
HgeneTgene
Gene symbol

ZMYND8

GNAI3

Gene ID

23613

2773

Gene namezinc finger MYND-type containing 8G protein subunit alpha i3
SynonymsPRKCBP1|PRO2893|RACK787U6|ARCND1
Cytomap

20q13.12

1p13.3

Type of geneprotein-codingprotein-coding
Descriptionprotein kinase C-binding protein 1CTCL tumor antigen se14-3cutaneous T-cell lymphoma-associated antigen se14-3predicted protein of HQ2893zinc finger MYND domain-containing protein 8guanine nucleotide-binding protein G(i) subunit alphag(i) alpha-3guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3guanine nucleotide-binding protein G(k) subunit alpha
Modification date2020031320200322
UniProtAcc.

P08754

Ensembl transtripts involved in fusion geneENST00000262975, ENST00000311275, 
ENST00000355972, ENST00000446994, 
ENST00000352431, ENST00000360911, 
ENST00000372023, ENST00000396281, 
ENST00000458360, ENST00000461685, 
ENST00000471951, ENST00000536340, 
ENST00000540497, ENST00000468376, 
ENST00000369851, 
Fusion gene scores* DoF score25 X 23 X 10=575033 X 8 X 14=3696
# samples 3435
** MAII scorelog2(34/5750*10)=-4.0799553045814
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(35/3696*10)=-3.40053792958373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZMYND8 [Title/Abstract] AND GNAI3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZMYND8(45976599)-GNAI3(110116358), # samples:2
Anticipated loss of major functional domain due to fusion event.ZMYND8-GNAI3 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
ZMYND8-GNAI3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ZMYND8-GNAI3 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneGNAI3

GO:0007193

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

19478087

TgeneGNAI3

GO:0007212

dopamine receptor signaling pathway

19478087

TgeneGNAI3

GO:0046039

GTP metabolic process

19478087

TgeneGNAI3

GO:0051301

cell division

17635935


check buttonFusion gene breakpoints across ZMYND8 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GNAI3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-2A-A8VOZMYND8chr20

45976599

-GNAI3chr1

110116358

+


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Fusion Gene ORF analysis for ZMYND8-GNAI3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000262975ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
Frame-shiftENST00000311275ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
Frame-shiftENST00000355972ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
Frame-shiftENST00000446994ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
In-frameENST00000352431ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
In-frameENST00000360911ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
In-frameENST00000372023ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
In-frameENST00000396281ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
In-frameENST00000458360ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
In-frameENST00000461685ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
In-frameENST00000471951ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
In-frameENST00000536340ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
In-frameENST00000540497ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+
intron-3CDSENST00000468376ENST00000369851ZMYND8chr20

45976599

-GNAI3chr1

110116358

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000360911ZMYND8chr2045976599-ENST00000369851GNAI3chr1110116358+3099121361067343
ENST00000458360ZMYND8chr2045976599-ENST00000369851GNAI3chr1110116358+3113135501081343
ENST00000471951ZMYND8chr2045976599-ENST00000369851GNAI3chr1110116358+3090112271058343
ENST00000352431ZMYND8chr2045976599-ENST00000369851GNAI3chr1110116358+3092114291060343
ENST00000396281ZMYND8chr2045976599-ENST00000369851GNAI3chr1110116358+32913132131259348
ENST00000536340ZMYND8chr2045976599-ENST00000369851GNAI3chr1110116358+3166188311134367
ENST00000540497ZMYND8chr2045976599-ENST00000369851GNAI3chr1110116358+30638501031343
ENST00000461685ZMYND8chr2045976599-ENST00000369851GNAI3chr1110116358+30638501031343
ENST00000372023ZMYND8chr2045976599-ENST00000369851GNAI3chr1110116358+30638501031343

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000360911ENST00000369851ZMYND8chr2045976599-GNAI3chr1110116358+0.0001372920.9998627
ENST00000458360ENST00000369851ZMYND8chr2045976599-GNAI3chr1110116358+0.0001374130.99986255
ENST00000471951ENST00000369851ZMYND8chr2045976599-GNAI3chr1110116358+0.0001407390.9998592
ENST00000352431ENST00000369851ZMYND8chr2045976599-GNAI3chr1110116358+0.0001404640.9998596
ENST00000396281ENST00000369851ZMYND8chr2045976599-GNAI3chr1110116358+0.0002179040.99978215
ENST00000536340ENST00000369851ZMYND8chr2045976599-GNAI3chr1110116358+0.0001019920.99989796
ENST00000540497ENST00000369851ZMYND8chr2045976599-GNAI3chr1110116358+0.0001467120.99985325
ENST00000461685ENST00000369851ZMYND8chr2045976599-GNAI3chr1110116358+0.0001467120.99985325
ENST00000372023ENST00000369851ZMYND8chr2045976599-GNAI3chr1110116358+0.0001467120.99985325

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Fusion Genomic Features for ZMYND8-GNAI3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZMYND8chr2045976599-GNAI3chr1110116358+6.55E-080.9999999
ZMYND8chr2045976599-GNAI3chr1110116358+6.55E-080.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZMYND8-GNAI3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:45976599/chr1:110116358)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.GNAI3

P08754

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins (PubMed:8774883, PubMed:18434541, PubMed:19478087). Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels (PubMed:19478087). Stimulates the activity of receptor-regulated K(+) channels (PubMed:2535845). The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division (PubMed:17635935). {ECO:0000269|PubMed:17635935, ECO:0000269|PubMed:18434541, ECO:0000269|PubMed:2535845, ECO:0000269|PubMed:8774883}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneGNAI3chr20:45976599chr1:110116358ENST0000036985109150_15139948.6666666666666Nucleotide bindingGTP
TgeneGNAI3chr20:45976599chr1:110116358ENST0000036985109175_18139948.6666666666666Nucleotide bindingGTP
TgeneGNAI3chr20:45976599chr1:110116358ENST0000036985109200_20439948.6666666666666Nucleotide bindingGTP
TgeneGNAI3chr20:45976599chr1:110116358ENST0000036985109269_27239948.6666666666666Nucleotide bindingGTP
TgeneGNAI3chr20:45976599chr1:110116358ENST000003698510943_4839948.6666666666666Nucleotide bindingGTP
TgeneGNAI3chr20:45976599chr1:110116358ENST0000036985109173_18139948.6666666666666RegionG2 motif
TgeneGNAI3chr20:45976599chr1:110116358ENST0000036985109196_20539948.6666666666666RegionG3 motif
TgeneGNAI3chr20:45976599chr1:110116358ENST0000036985109265_27239948.6666666666666RegionG4 motif
TgeneGNAI3chr20:45976599chr1:110116358ENST0000036985109324_32939948.6666666666666RegionG5 motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZMYND8chr20:45976599chr1:110116358ENST00000262975-3241089_109281169.0Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976599chr1:110116358ENST00000262975-32443_4781169.0Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976599chr1:110116358ENST00000262975-324838_85481169.0Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976599chr1:110116358ENST00000311275-2221089_109281187.0Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976599chr1:110116358ENST00000311275-22243_4781187.0Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976599chr1:110116358ENST00000311275-222838_85481187.0Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976599chr1:110116358ENST00000352431-2221089_1092281161.0Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976599chr1:110116358ENST00000352431-22243_47281161.0Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976599chr1:110116358ENST00000352431-222838_854281161.0Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976599chr1:110116358ENST00000355972-3241089_109281215.0Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976599chr1:110116358ENST00000355972-32443_4781215.0Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976599chr1:110116358ENST00000355972-324838_85481215.0Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976599chr1:110116358ENST00000360911-2221089_1092281136.0Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976599chr1:110116358ENST00000360911-22243_47281136.0Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976599chr1:110116358ENST00000360911-222838_854281136.0Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976599chr1:110116358ENST00000461685-2231089_1092281189.0Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976599chr1:110116358ENST00000461685-22343_47281189.0Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976599chr1:110116358ENST00000461685-223838_854281189.0Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976599chr1:110116358ENST00000471951-2231089_1092281235.0Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976599chr1:110116358ENST00000471951-22343_47281235.0Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976599chr1:110116358ENST00000471951-223838_854281235.0Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976599chr1:110116358ENST00000262975-324165_23581169.0DomainBromo
HgeneZMYND8chr20:45976599chr1:110116358ENST00000262975-324277_32781169.0DomainPWWP
HgeneZMYND8chr20:45976599chr1:110116358ENST00000311275-222165_23581187.0DomainBromo
HgeneZMYND8chr20:45976599chr1:110116358ENST00000311275-222277_32781187.0DomainPWWP
HgeneZMYND8chr20:45976599chr1:110116358ENST00000352431-222165_235281161.0DomainBromo
HgeneZMYND8chr20:45976599chr1:110116358ENST00000352431-222277_327281161.0DomainPWWP
HgeneZMYND8chr20:45976599chr1:110116358ENST00000355972-324165_23581215.0DomainBromo
HgeneZMYND8chr20:45976599chr1:110116358ENST00000355972-324277_32781215.0DomainPWWP
HgeneZMYND8chr20:45976599chr1:110116358ENST00000360911-222165_235281136.0DomainBromo
HgeneZMYND8chr20:45976599chr1:110116358ENST00000360911-222277_327281136.0DomainPWWP
HgeneZMYND8chr20:45976599chr1:110116358ENST00000461685-223165_235281189.0DomainBromo
HgeneZMYND8chr20:45976599chr1:110116358ENST00000461685-223277_327281189.0DomainPWWP
HgeneZMYND8chr20:45976599chr1:110116358ENST00000471951-223165_235281235.0DomainBromo
HgeneZMYND8chr20:45976599chr1:110116358ENST00000471951-223277_327281235.0DomainPWWP
HgeneZMYND8chr20:45976599chr1:110116358ENST00000262975-3241028_106281169.0Zinc fingerMYND-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000262975-32488_13381169.0Zinc fingerPHD-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000311275-2221028_106281187.0Zinc fingerMYND-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000311275-22288_13381187.0Zinc fingerPHD-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000352431-2221028_1062281161.0Zinc fingerMYND-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000352431-22288_133281161.0Zinc fingerPHD-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000355972-3241028_106281215.0Zinc fingerMYND-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000355972-32488_13381215.0Zinc fingerPHD-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000360911-2221028_1062281136.0Zinc fingerMYND-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000360911-22288_133281136.0Zinc fingerPHD-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000461685-2231028_1062281189.0Zinc fingerMYND-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000461685-22388_133281189.0Zinc fingerPHD-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000471951-2231028_1062281235.0Zinc fingerMYND-type
HgeneZMYND8chr20:45976599chr1:110116358ENST00000471951-22388_133281235.0Zinc fingerPHD-type
TgeneGNAI3chr20:45976599chr1:110116358ENST000003698510932_35439948.6666666666666DomainG-alpha
TgeneGNAI3chr20:45976599chr1:110116358ENST000003698510935_4839948.6666666666666RegionG1 motif


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Fusion Gene Sequence for ZMYND8-GNAI3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>101403_101403_1_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000352431_GNAI3_chr1_110116358_ENST00000369851_length(transcript)=3092nt_BP=114nt
ATAAGTATTGACATTACACAGTGTTAACAATGCATCCACAGAGCTTGGCTGAAGAGGAAATAAAAACAGAACAGGAGGTGGTAGAGGGCA
TGGATATCTCTACTCGCTCCAAAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAACAGATGAAAATCATTCATGAGGATGGCTATT
CAGAGGATGAATGTAAACAATATAAAGTAGTTGTCTACAGCAATACTATACAGTCCATCATTGCAATCATAAGAGCCATGGGACGGCTAA
AGATTGACTTTGGGGAAGCTGCCAGGGCAGATGATGCCCGGCAATTATTTGTTTTAGCTGGCAGTGCTGAAGAAGGAGTCATGACTCCAG
AACTAGCAGGAGTGATTAAACGGTTATGGCGAGATGGTGGGGTACAAGCTTGCTTCAGCAGATCCAGGGAATATCAGCTCAATGATTCTG
CTTCATATTATCTAAATGATCTGGATAGAATATCCCAGTCTAACTACATTCCAACTCAGCAAGATGTTCTTCGGACGAGAGTGAAGACCA
CAGGCATTGTAGAAACACATTTCACCTTCAAAGACCTATACTTCAAGATGTTTGATGTAGGTGGCCAAAGATCAGAACGAAAAAAGTGGA
TTCACTGTTTTGAGGGAGTGACAGCAATTATCTTCTGTGTGGCCCTCAGTGATTATGACCTTGTTCTGGCTGAGGACGAGGAGATGAACC
GAATGCATGAAAGCATGAAACTGTTTGACAGCATTTGTAATAACAAATGGTTTACAGAAACTTCAATCATTCTCTTCCTTAACAAGAAAG
ACCTTTTTGAGGAAAAAATAAAGAGGAGTCCGTTAACTATCTGTTATCCAGAATACACAGGTTCCAATACATATGAAGAGGCAGCTGCCT
ATATTCAATGCCAGTTTGAAGATCTGAACAGAAGAAAAGATACCAAGGAGATCTATACTCACTTCACCTGTGCCACAGACACGAAGAATG
TGCAGTTTGTTTTTGATGCTGTTACAGATGTCATCATTAAAAACAACTTAAAGGAATGTGGACTTTATTGAGAAGCATGGATGTTAGTGA
AAGTTACTACAGTGTGGAGTGTTGAGACCAGACACCTTTTGCTGTCTCATGGGGCAGCTACAAGCATGAACGGGACCAGGGAATGGCAGC
AGCATGCAGAATCTTAGCACTCTTTAGCACAATATTTTGTATTAGGGAACTTTTAATTGACATGAGATGCTAAAGTCAGACATTGGAATT
GGAAGAACTATAAAGTGTGATTCGATCGTCAAGACATCACTTGGATTTCTTAATCTTAAATGCTTATGGAAGATGTGAAGTTGAGGTGCT
GCATTCTAGAACTTCAATATGTAGCTTACTCTTTTTTTCCCCCCTTCTTAAACCACCAGTGGTTCATTTTTAAGGTTTTTTCATCAAGAG
AAGAATAACTTTACTAAATTTTATTTCTTTATTTGCAAAAGAATCTTTATTAAAACAAACAATCTTAACTATGCACATGATGTGACCAGA
TCATCTTGAAAATATTCCTCTTTAGTAGGAACTCTTTGTTTTTAACTCTTGGTATGGTCAGAATATAATACTTCCATAATTACTTATAAT
TCTTTCCGGTTACTGGGGCTATAAATACAACTTTTTAAATGAAATTTATGTTATTATCCTGCTCAAAGTACCATTATGGTTTCCATATGG
TAATTACATTGGAAAGTTCTGCAATAAGATTCTAGTTCTCTCTTTTCTTTAAGCTTATGGTTGAAGGTTAACCTTGTTTGTGCAGATTAC
CAAATTACTGCTGATGTAGTATGATAAAGTCAGCTTCTTGGATACAGACACACCCAGGGCAGCTGCCAATCAGAAATGCAAATTGCTAAA
TTCCAAACAGAACCAGTGACTTTGCTGCTACATATTTACTAAATTGACCACTTTGATTCTTGCTTGTTTGTCTCAGTTATAGGGAGTTTT
GTACATGGTGCCTCTTGTTTTCCATCTTCATGGCCTTTTCTGTTGAGAAACATCTAAAGTGTATTAACAGTGCATGCTTTTACTTTGTAA
ATGTGGTGCCAAATCCCTGTTTGCCATCGTTTTTACTGTACCGATGTTAACTGTAGTAATCCTTAGCCAGTATGTTCTTTTGCTGAAACT
GTTGCATTTTGGGACTTTTTTCCACTTTGTCATGTGTACATTTTTAATCTGTTATAGTTGGCGGCAGTATTAAAATGGTGAGTAAAGAGC
CCAGGTTTGCTCCTGTTTGTAACTAGTCTTTTCTGGAAATACTGTCTTCTGTTTCCTTTTGCCTTTGCAGAATGTGCTTTAGCCTTTGTC
TGAGAATGGGTTTAGGTAGAAGGGTTTCCTGAAAGTCTAGTCTTTTGGTGTAATAGTATTGTTGAACCTTAGGTTTTATGTTATATCTGC
ATATGAGTGATATGTGATCATGATTCATTTTGCAGATTTACATTTTGCTTGTGTGGAAAGTTACGTTCACTTCAACCTACAGACCCTTTT
GTATAATGTACAGCAAATGTCATTAAATATTGAATGCTCTATTGGGGGAAGACAAATGAAGAGAATGCATTTTGAGCATTTCAAATCAGT
AGTTTGGGCAGTGCCTTTTGGGGTCCAATCTTTTTGGATTGGATTCTATTTCATCTTTTGATGTGACTTTTCACTAGTTTACAAAAAAAA
GGTTGGTGGTCAACAAAAAAAGCAAGTCATAGCAGTTCAGTGCCTTTGTTGGTAGTTTTTAACTTTTTTTGTGATTCTTTTTGGAAAATC
ATAGCTTACAGATGGTATAACTGTATTATATAATGGAATTTTCTTTAGGTGTGGGAAAACTTGATCTGAAAGAAAATTATCAGCTTCAAT
TGGCGATTGATTCAGTGCCCACAATGTAAACAGGGTTGGTAGTTGTTACTCATTTTGAATATACCTTTTCCTTATTGTATTCTGTAATAT
AGGATCCTGGAAATGAGACCTGGTGGAATATTATTTTCAACTGTAGTCTTTCTATACTGTGGACTAATGAAATGGTGTTGTTGATAATCT

>101403_101403_1_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000352431_GNAI3_chr1_110116358_ENST00000369851_length(amino acids)=343AA_BP=28
MHPQSLAEEEIKTEQEVVEGMDISTRSKGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARA
DDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTF
KDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRS

--------------------------------------------------------------
>101403_101403_2_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000360911_GNAI3_chr1_110116358_ENST00000369851_length(transcript)=3099nt_BP=121nt
ATGTTTTATAAGTATTGACATTACACAGTGTTAACAATGCATCCACAGAGCTTGGCTGAAGAGGAAATAAAAACAGAACAGGAGGTGGTA
GAGGGCATGGATATCTCTACTCGCTCCAAAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAACAGATGAAAATCATTCATGAGGAT
GGCTATTCAGAGGATGAATGTAAACAATATAAAGTAGTTGTCTACAGCAATACTATACAGTCCATCATTGCAATCATAAGAGCCATGGGA
CGGCTAAAGATTGACTTTGGGGAAGCTGCCAGGGCAGATGATGCCCGGCAATTATTTGTTTTAGCTGGCAGTGCTGAAGAAGGAGTCATG
ACTCCAGAACTAGCAGGAGTGATTAAACGGTTATGGCGAGATGGTGGGGTACAAGCTTGCTTCAGCAGATCCAGGGAATATCAGCTCAAT
GATTCTGCTTCATATTATCTAAATGATCTGGATAGAATATCCCAGTCTAACTACATTCCAACTCAGCAAGATGTTCTTCGGACGAGAGTG
AAGACCACAGGCATTGTAGAAACACATTTCACCTTCAAAGACCTATACTTCAAGATGTTTGATGTAGGTGGCCAAAGATCAGAACGAAAA
AAGTGGATTCACTGTTTTGAGGGAGTGACAGCAATTATCTTCTGTGTGGCCCTCAGTGATTATGACCTTGTTCTGGCTGAGGACGAGGAG
ATGAACCGAATGCATGAAAGCATGAAACTGTTTGACAGCATTTGTAATAACAAATGGTTTACAGAAACTTCAATCATTCTCTTCCTTAAC
AAGAAAGACCTTTTTGAGGAAAAAATAAAGAGGAGTCCGTTAACTATCTGTTATCCAGAATACACAGGTTCCAATACATATGAAGAGGCA
GCTGCCTATATTCAATGCCAGTTTGAAGATCTGAACAGAAGAAAAGATACCAAGGAGATCTATACTCACTTCACCTGTGCCACAGACACG
AAGAATGTGCAGTTTGTTTTTGATGCTGTTACAGATGTCATCATTAAAAACAACTTAAAGGAATGTGGACTTTATTGAGAAGCATGGATG
TTAGTGAAAGTTACTACAGTGTGGAGTGTTGAGACCAGACACCTTTTGCTGTCTCATGGGGCAGCTACAAGCATGAACGGGACCAGGGAA
TGGCAGCAGCATGCAGAATCTTAGCACTCTTTAGCACAATATTTTGTATTAGGGAACTTTTAATTGACATGAGATGCTAAAGTCAGACAT
TGGAATTGGAAGAACTATAAAGTGTGATTCGATCGTCAAGACATCACTTGGATTTCTTAATCTTAAATGCTTATGGAAGATGTGAAGTTG
AGGTGCTGCATTCTAGAACTTCAATATGTAGCTTACTCTTTTTTTCCCCCCTTCTTAAACCACCAGTGGTTCATTTTTAAGGTTTTTTCA
TCAAGAGAAGAATAACTTTACTAAATTTTATTTCTTTATTTGCAAAAGAATCTTTATTAAAACAAACAATCTTAACTATGCACATGATGT
GACCAGATCATCTTGAAAATATTCCTCTTTAGTAGGAACTCTTTGTTTTTAACTCTTGGTATGGTCAGAATATAATACTTCCATAATTAC
TTATAATTCTTTCCGGTTACTGGGGCTATAAATACAACTTTTTAAATGAAATTTATGTTATTATCCTGCTCAAAGTACCATTATGGTTTC
CATATGGTAATTACATTGGAAAGTTCTGCAATAAGATTCTAGTTCTCTCTTTTCTTTAAGCTTATGGTTGAAGGTTAACCTTGTTTGTGC
AGATTACCAAATTACTGCTGATGTAGTATGATAAAGTCAGCTTCTTGGATACAGACACACCCAGGGCAGCTGCCAATCAGAAATGCAAAT
TGCTAAATTCCAAACAGAACCAGTGACTTTGCTGCTACATATTTACTAAATTGACCACTTTGATTCTTGCTTGTTTGTCTCAGTTATAGG
GAGTTTTGTACATGGTGCCTCTTGTTTTCCATCTTCATGGCCTTTTCTGTTGAGAAACATCTAAAGTGTATTAACAGTGCATGCTTTTAC
TTTGTAAATGTGGTGCCAAATCCCTGTTTGCCATCGTTTTTACTGTACCGATGTTAACTGTAGTAATCCTTAGCCAGTATGTTCTTTTGC
TGAAACTGTTGCATTTTGGGACTTTTTTCCACTTTGTCATGTGTACATTTTTAATCTGTTATAGTTGGCGGCAGTATTAAAATGGTGAGT
AAAGAGCCCAGGTTTGCTCCTGTTTGTAACTAGTCTTTTCTGGAAATACTGTCTTCTGTTTCCTTTTGCCTTTGCAGAATGTGCTTTAGC
CTTTGTCTGAGAATGGGTTTAGGTAGAAGGGTTTCCTGAAAGTCTAGTCTTTTGGTGTAATAGTATTGTTGAACCTTAGGTTTTATGTTA
TATCTGCATATGAGTGATATGTGATCATGATTCATTTTGCAGATTTACATTTTGCTTGTGTGGAAAGTTACGTTCACTTCAACCTACAGA
CCCTTTTGTATAATGTACAGCAAATGTCATTAAATATTGAATGCTCTATTGGGGGAAGACAAATGAAGAGAATGCATTTTGAGCATTTCA
AATCAGTAGTTTGGGCAGTGCCTTTTGGGGTCCAATCTTTTTGGATTGGATTCTATTTCATCTTTTGATGTGACTTTTCACTAGTTTACA
AAAAAAAGGTTGGTGGTCAACAAAAAAAGCAAGTCATAGCAGTTCAGTGCCTTTGTTGGTAGTTTTTAACTTTTTTTGTGATTCTTTTTG
GAAAATCATAGCTTACAGATGGTATAACTGTATTATATAATGGAATTTTCTTTAGGTGTGGGAAAACTTGATCTGAAAGAAAATTATCAG
CTTCAATTGGCGATTGATTCAGTGCCCACAATGTAAACAGGGTTGGTAGTTGTTACTCATTTTGAATATACCTTTTCCTTATTGTATTCT
GTAATATAGGATCCTGGAAATGAGACCTGGTGGAATATTATTTTCAACTGTAGTCTTTCTATACTGTGGACTAATGAAATGGTGTTGTTG

>101403_101403_2_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000360911_GNAI3_chr1_110116358_ENST00000369851_length(amino acids)=343AA_BP=28
MHPQSLAEEEIKTEQEVVEGMDISTRSKGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARA
DDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTF
KDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRS

--------------------------------------------------------------
>101403_101403_3_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000372023_GNAI3_chr1_110116358_ENST00000369851_length(transcript)=3063nt_BP=85nt
ATGCATCCACAGAGCTTGGCTGAAGAGGAAATAAAAACAGAACAGGAGGTGGTAGAGGGCATGGATATCTCTACTCGCTCCAAAGGTGCT
GGAGAATCTGGTAAAAGCACCATTGTGAAACAGATGAAAATCATTCATGAGGATGGCTATTCAGAGGATGAATGTAAACAATATAAAGTA
GTTGTCTACAGCAATACTATACAGTCCATCATTGCAATCATAAGAGCCATGGGACGGCTAAAGATTGACTTTGGGGAAGCTGCCAGGGCA
GATGATGCCCGGCAATTATTTGTTTTAGCTGGCAGTGCTGAAGAAGGAGTCATGACTCCAGAACTAGCAGGAGTGATTAAACGGTTATGG
CGAGATGGTGGGGTACAAGCTTGCTTCAGCAGATCCAGGGAATATCAGCTCAATGATTCTGCTTCATATTATCTAAATGATCTGGATAGA
ATATCCCAGTCTAACTACATTCCAACTCAGCAAGATGTTCTTCGGACGAGAGTGAAGACCACAGGCATTGTAGAAACACATTTCACCTTC
AAAGACCTATACTTCAAGATGTTTGATGTAGGTGGCCAAAGATCAGAACGAAAAAAGTGGATTCACTGTTTTGAGGGAGTGACAGCAATT
ATCTTCTGTGTGGCCCTCAGTGATTATGACCTTGTTCTGGCTGAGGACGAGGAGATGAACCGAATGCATGAAAGCATGAAACTGTTTGAC
AGCATTTGTAATAACAAATGGTTTACAGAAACTTCAATCATTCTCTTCCTTAACAAGAAAGACCTTTTTGAGGAAAAAATAAAGAGGAGT
CCGTTAACTATCTGTTATCCAGAATACACAGGTTCCAATACATATGAAGAGGCAGCTGCCTATATTCAATGCCAGTTTGAAGATCTGAAC
AGAAGAAAAGATACCAAGGAGATCTATACTCACTTCACCTGTGCCACAGACACGAAGAATGTGCAGTTTGTTTTTGATGCTGTTACAGAT
GTCATCATTAAAAACAACTTAAAGGAATGTGGACTTTATTGAGAAGCATGGATGTTAGTGAAAGTTACTACAGTGTGGAGTGTTGAGACC
AGACACCTTTTGCTGTCTCATGGGGCAGCTACAAGCATGAACGGGACCAGGGAATGGCAGCAGCATGCAGAATCTTAGCACTCTTTAGCA
CAATATTTTGTATTAGGGAACTTTTAATTGACATGAGATGCTAAAGTCAGACATTGGAATTGGAAGAACTATAAAGTGTGATTCGATCGT
CAAGACATCACTTGGATTTCTTAATCTTAAATGCTTATGGAAGATGTGAAGTTGAGGTGCTGCATTCTAGAACTTCAATATGTAGCTTAC
TCTTTTTTTCCCCCCTTCTTAAACCACCAGTGGTTCATTTTTAAGGTTTTTTCATCAAGAGAAGAATAACTTTACTAAATTTTATTTCTT
TATTTGCAAAAGAATCTTTATTAAAACAAACAATCTTAACTATGCACATGATGTGACCAGATCATCTTGAAAATATTCCTCTTTAGTAGG
AACTCTTTGTTTTTAACTCTTGGTATGGTCAGAATATAATACTTCCATAATTACTTATAATTCTTTCCGGTTACTGGGGCTATAAATACA
ACTTTTTAAATGAAATTTATGTTATTATCCTGCTCAAAGTACCATTATGGTTTCCATATGGTAATTACATTGGAAAGTTCTGCAATAAGA
TTCTAGTTCTCTCTTTTCTTTAAGCTTATGGTTGAAGGTTAACCTTGTTTGTGCAGATTACCAAATTACTGCTGATGTAGTATGATAAAG
TCAGCTTCTTGGATACAGACACACCCAGGGCAGCTGCCAATCAGAAATGCAAATTGCTAAATTCCAAACAGAACCAGTGACTTTGCTGCT
ACATATTTACTAAATTGACCACTTTGATTCTTGCTTGTTTGTCTCAGTTATAGGGAGTTTTGTACATGGTGCCTCTTGTTTTCCATCTTC
ATGGCCTTTTCTGTTGAGAAACATCTAAAGTGTATTAACAGTGCATGCTTTTACTTTGTAAATGTGGTGCCAAATCCCTGTTTGCCATCG
TTTTTACTGTACCGATGTTAACTGTAGTAATCCTTAGCCAGTATGTTCTTTTGCTGAAACTGTTGCATTTTGGGACTTTTTTCCACTTTG
TCATGTGTACATTTTTAATCTGTTATAGTTGGCGGCAGTATTAAAATGGTGAGTAAAGAGCCCAGGTTTGCTCCTGTTTGTAACTAGTCT
TTTCTGGAAATACTGTCTTCTGTTTCCTTTTGCCTTTGCAGAATGTGCTTTAGCCTTTGTCTGAGAATGGGTTTAGGTAGAAGGGTTTCC
TGAAAGTCTAGTCTTTTGGTGTAATAGTATTGTTGAACCTTAGGTTTTATGTTATATCTGCATATGAGTGATATGTGATCATGATTCATT
TTGCAGATTTACATTTTGCTTGTGTGGAAAGTTACGTTCACTTCAACCTACAGACCCTTTTGTATAATGTACAGCAAATGTCATTAAATA
TTGAATGCTCTATTGGGGGAAGACAAATGAAGAGAATGCATTTTGAGCATTTCAAATCAGTAGTTTGGGCAGTGCCTTTTGGGGTCCAAT
CTTTTTGGATTGGATTCTATTTCATCTTTTGATGTGACTTTTCACTAGTTTACAAAAAAAAGGTTGGTGGTCAACAAAAAAAGCAAGTCA
TAGCAGTTCAGTGCCTTTGTTGGTAGTTTTTAACTTTTTTTGTGATTCTTTTTGGAAAATCATAGCTTACAGATGGTATAACTGTATTAT
ATAATGGAATTTTCTTTAGGTGTGGGAAAACTTGATCTGAAAGAAAATTATCAGCTTCAATTGGCGATTGATTCAGTGCCCACAATGTAA
ACAGGGTTGGTAGTTGTTACTCATTTTGAATATACCTTTTCCTTATTGTATTCTGTAATATAGGATCCTGGAAATGAGACCTGGTGGAAT
ATTATTTTCAACTGTAGTCTTTCTATACTGTGGACTAATGAAATGGTGTTGTTGATAATCTAAAATAACCAATAATCCAAAAAAGTTCAT

>101403_101403_3_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000372023_GNAI3_chr1_110116358_ENST00000369851_length(amino acids)=343AA_BP=28
MHPQSLAEEEIKTEQEVVEGMDISTRSKGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARA
DDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTF
KDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRS

--------------------------------------------------------------
>101403_101403_4_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000396281_GNAI3_chr1_110116358_ENST00000369851_length(transcript)=3291nt_BP=313nt
ATAAGTATTGACATTACACAGTGTTAACAATGCATCCACAGAGTCCCAAATCTGCCAGCCTGTTCTCTCTTCCTAACTGTGGAAAAATGA
GACGGTTGCTTGAACATTTGTTGGCAGCATTCCTGCCTGAAGTATTCAGCTCCTCTAGGCTGTTACAAGCCAAATAATGGTTCCCTTGAA
TGCAGCCTTCCTCCATGATCAATACACCTTTGAATGTTTTCATCGCTGCAGAAATCCTTCAACTTGGCTGAAGAGGAAATAAAAACAGAA
CAGGAGGTGGTAGAGGGCATGGATATCTCTACTCGCTCCAAAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAACAGATGAAAATC
ATTCATGAGGATGGCTATTCAGAGGATGAATGTAAACAATATAAAGTAGTTGTCTACAGCAATACTATACAGTCCATCATTGCAATCATA
AGAGCCATGGGACGGCTAAAGATTGACTTTGGGGAAGCTGCCAGGGCAGATGATGCCCGGCAATTATTTGTTTTAGCTGGCAGTGCTGAA
GAAGGAGTCATGACTCCAGAACTAGCAGGAGTGATTAAACGGTTATGGCGAGATGGTGGGGTACAAGCTTGCTTCAGCAGATCCAGGGAA
TATCAGCTCAATGATTCTGCTTCATATTATCTAAATGATCTGGATAGAATATCCCAGTCTAACTACATTCCAACTCAGCAAGATGTTCTT
CGGACGAGAGTGAAGACCACAGGCATTGTAGAAACACATTTCACCTTCAAAGACCTATACTTCAAGATGTTTGATGTAGGTGGCCAAAGA
TCAGAACGAAAAAAGTGGATTCACTGTTTTGAGGGAGTGACAGCAATTATCTTCTGTGTGGCCCTCAGTGATTATGACCTTGTTCTGGCT
GAGGACGAGGAGATGAACCGAATGCATGAAAGCATGAAACTGTTTGACAGCATTTGTAATAACAAATGGTTTACAGAAACTTCAATCATT
CTCTTCCTTAACAAGAAAGACCTTTTTGAGGAAAAAATAAAGAGGAGTCCGTTAACTATCTGTTATCCAGAATACACAGGTTCCAATACA
TATGAAGAGGCAGCTGCCTATATTCAATGCCAGTTTGAAGATCTGAACAGAAGAAAAGATACCAAGGAGATCTATACTCACTTCACCTGT
GCCACAGACACGAAGAATGTGCAGTTTGTTTTTGATGCTGTTACAGATGTCATCATTAAAAACAACTTAAAGGAATGTGGACTTTATTGA
GAAGCATGGATGTTAGTGAAAGTTACTACAGTGTGGAGTGTTGAGACCAGACACCTTTTGCTGTCTCATGGGGCAGCTACAAGCATGAAC
GGGACCAGGGAATGGCAGCAGCATGCAGAATCTTAGCACTCTTTAGCACAATATTTTGTATTAGGGAACTTTTAATTGACATGAGATGCT
AAAGTCAGACATTGGAATTGGAAGAACTATAAAGTGTGATTCGATCGTCAAGACATCACTTGGATTTCTTAATCTTAAATGCTTATGGAA
GATGTGAAGTTGAGGTGCTGCATTCTAGAACTTCAATATGTAGCTTACTCTTTTTTTCCCCCCTTCTTAAACCACCAGTGGTTCATTTTT
AAGGTTTTTTCATCAAGAGAAGAATAACTTTACTAAATTTTATTTCTTTATTTGCAAAAGAATCTTTATTAAAACAAACAATCTTAACTA
TGCACATGATGTGACCAGATCATCTTGAAAATATTCCTCTTTAGTAGGAACTCTTTGTTTTTAACTCTTGGTATGGTCAGAATATAATAC
TTCCATAATTACTTATAATTCTTTCCGGTTACTGGGGCTATAAATACAACTTTTTAAATGAAATTTATGTTATTATCCTGCTCAAAGTAC
CATTATGGTTTCCATATGGTAATTACATTGGAAAGTTCTGCAATAAGATTCTAGTTCTCTCTTTTCTTTAAGCTTATGGTTGAAGGTTAA
CCTTGTTTGTGCAGATTACCAAATTACTGCTGATGTAGTATGATAAAGTCAGCTTCTTGGATACAGACACACCCAGGGCAGCTGCCAATC
AGAAATGCAAATTGCTAAATTCCAAACAGAACCAGTGACTTTGCTGCTACATATTTACTAAATTGACCACTTTGATTCTTGCTTGTTTGT
CTCAGTTATAGGGAGTTTTGTACATGGTGCCTCTTGTTTTCCATCTTCATGGCCTTTTCTGTTGAGAAACATCTAAAGTGTATTAACAGT
GCATGCTTTTACTTTGTAAATGTGGTGCCAAATCCCTGTTTGCCATCGTTTTTACTGTACCGATGTTAACTGTAGTAATCCTTAGCCAGT
ATGTTCTTTTGCTGAAACTGTTGCATTTTGGGACTTTTTTCCACTTTGTCATGTGTACATTTTTAATCTGTTATAGTTGGCGGCAGTATT
AAAATGGTGAGTAAAGAGCCCAGGTTTGCTCCTGTTTGTAACTAGTCTTTTCTGGAAATACTGTCTTCTGTTTCCTTTTGCCTTTGCAGA
ATGTGCTTTAGCCTTTGTCTGAGAATGGGTTTAGGTAGAAGGGTTTCCTGAAAGTCTAGTCTTTTGGTGTAATAGTATTGTTGAACCTTA
GGTTTTATGTTATATCTGCATATGAGTGATATGTGATCATGATTCATTTTGCAGATTTACATTTTGCTTGTGTGGAAAGTTACGTTCACT
TCAACCTACAGACCCTTTTGTATAATGTACAGCAAATGTCATTAAATATTGAATGCTCTATTGGGGGAAGACAAATGAAGAGAATGCATT
TTGAGCATTTCAAATCAGTAGTTTGGGCAGTGCCTTTTGGGGTCCAATCTTTTTGGATTGGATTCTATTTCATCTTTTGATGTGACTTTT
CACTAGTTTACAAAAAAAAGGTTGGTGGTCAACAAAAAAAGCAAGTCATAGCAGTTCAGTGCCTTTGTTGGTAGTTTTTAACTTTTTTTG
TGATTCTTTTTGGAAAATCATAGCTTACAGATGGTATAACTGTATTATATAATGGAATTTTCTTTAGGTGTGGGAAAACTTGATCTGAAA
GAAAATTATCAGCTTCAATTGGCGATTGATTCAGTGCCCACAATGTAAACAGGGTTGGTAGTTGTTACTCATTTTGAATATACCTTTTCC
TTATTGTATTCTGTAATATAGGATCCTGGAAATGAGACCTGGTGGAATATTATTTTCAACTGTAGTCTTTCTATACTGTGGACTAATGAA

>101403_101403_4_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000396281_GNAI3_chr1_110116358_ENST00000369851_length(amino acids)=348AA_BP=33
MFSSLQKSFNLAEEEIKTEQEVVEGMDISTRSKGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFG
EAARADDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVE
THFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEE

--------------------------------------------------------------
>101403_101403_5_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000458360_GNAI3_chr1_110116358_ENST00000369851_length(transcript)=3113nt_BP=135nt
GGAGCCTGTCCTCCATGTTTTATAAGTATTGACATTACACAGTGTTAACAATGCATCCACAGAGCTTGGCTGAAGAGGAAATAAAAACAG
AACAGGAGGTGGTAGAGGGCATGGATATCTCTACTCGCTCCAAAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAACAGATGAAAA
TCATTCATGAGGATGGCTATTCAGAGGATGAATGTAAACAATATAAAGTAGTTGTCTACAGCAATACTATACAGTCCATCATTGCAATCA
TAAGAGCCATGGGACGGCTAAAGATTGACTTTGGGGAAGCTGCCAGGGCAGATGATGCCCGGCAATTATTTGTTTTAGCTGGCAGTGCTG
AAGAAGGAGTCATGACTCCAGAACTAGCAGGAGTGATTAAACGGTTATGGCGAGATGGTGGGGTACAAGCTTGCTTCAGCAGATCCAGGG
AATATCAGCTCAATGATTCTGCTTCATATTATCTAAATGATCTGGATAGAATATCCCAGTCTAACTACATTCCAACTCAGCAAGATGTTC
TTCGGACGAGAGTGAAGACCACAGGCATTGTAGAAACACATTTCACCTTCAAAGACCTATACTTCAAGATGTTTGATGTAGGTGGCCAAA
GATCAGAACGAAAAAAGTGGATTCACTGTTTTGAGGGAGTGACAGCAATTATCTTCTGTGTGGCCCTCAGTGATTATGACCTTGTTCTGG
CTGAGGACGAGGAGATGAACCGAATGCATGAAAGCATGAAACTGTTTGACAGCATTTGTAATAACAAATGGTTTACAGAAACTTCAATCA
TTCTCTTCCTTAACAAGAAAGACCTTTTTGAGGAAAAAATAAAGAGGAGTCCGTTAACTATCTGTTATCCAGAATACACAGGTTCCAATA
CATATGAAGAGGCAGCTGCCTATATTCAATGCCAGTTTGAAGATCTGAACAGAAGAAAAGATACCAAGGAGATCTATACTCACTTCACCT
GTGCCACAGACACGAAGAATGTGCAGTTTGTTTTTGATGCTGTTACAGATGTCATCATTAAAAACAACTTAAAGGAATGTGGACTTTATT
GAGAAGCATGGATGTTAGTGAAAGTTACTACAGTGTGGAGTGTTGAGACCAGACACCTTTTGCTGTCTCATGGGGCAGCTACAAGCATGA
ACGGGACCAGGGAATGGCAGCAGCATGCAGAATCTTAGCACTCTTTAGCACAATATTTTGTATTAGGGAACTTTTAATTGACATGAGATG
CTAAAGTCAGACATTGGAATTGGAAGAACTATAAAGTGTGATTCGATCGTCAAGACATCACTTGGATTTCTTAATCTTAAATGCTTATGG
AAGATGTGAAGTTGAGGTGCTGCATTCTAGAACTTCAATATGTAGCTTACTCTTTTTTTCCCCCCTTCTTAAACCACCAGTGGTTCATTT
TTAAGGTTTTTTCATCAAGAGAAGAATAACTTTACTAAATTTTATTTCTTTATTTGCAAAAGAATCTTTATTAAAACAAACAATCTTAAC
TATGCACATGATGTGACCAGATCATCTTGAAAATATTCCTCTTTAGTAGGAACTCTTTGTTTTTAACTCTTGGTATGGTCAGAATATAAT
ACTTCCATAATTACTTATAATTCTTTCCGGTTACTGGGGCTATAAATACAACTTTTTAAATGAAATTTATGTTATTATCCTGCTCAAAGT
ACCATTATGGTTTCCATATGGTAATTACATTGGAAAGTTCTGCAATAAGATTCTAGTTCTCTCTTTTCTTTAAGCTTATGGTTGAAGGTT
AACCTTGTTTGTGCAGATTACCAAATTACTGCTGATGTAGTATGATAAAGTCAGCTTCTTGGATACAGACACACCCAGGGCAGCTGCCAA
TCAGAAATGCAAATTGCTAAATTCCAAACAGAACCAGTGACTTTGCTGCTACATATTTACTAAATTGACCACTTTGATTCTTGCTTGTTT
GTCTCAGTTATAGGGAGTTTTGTACATGGTGCCTCTTGTTTTCCATCTTCATGGCCTTTTCTGTTGAGAAACATCTAAAGTGTATTAACA
GTGCATGCTTTTACTTTGTAAATGTGGTGCCAAATCCCTGTTTGCCATCGTTTTTACTGTACCGATGTTAACTGTAGTAATCCTTAGCCA
GTATGTTCTTTTGCTGAAACTGTTGCATTTTGGGACTTTTTTCCACTTTGTCATGTGTACATTTTTAATCTGTTATAGTTGGCGGCAGTA
TTAAAATGGTGAGTAAAGAGCCCAGGTTTGCTCCTGTTTGTAACTAGTCTTTTCTGGAAATACTGTCTTCTGTTTCCTTTTGCCTTTGCA
GAATGTGCTTTAGCCTTTGTCTGAGAATGGGTTTAGGTAGAAGGGTTTCCTGAAAGTCTAGTCTTTTGGTGTAATAGTATTGTTGAACCT
TAGGTTTTATGTTATATCTGCATATGAGTGATATGTGATCATGATTCATTTTGCAGATTTACATTTTGCTTGTGTGGAAAGTTACGTTCA
CTTCAACCTACAGACCCTTTTGTATAATGTACAGCAAATGTCATTAAATATTGAATGCTCTATTGGGGGAAGACAAATGAAGAGAATGCA
TTTTGAGCATTTCAAATCAGTAGTTTGGGCAGTGCCTTTTGGGGTCCAATCTTTTTGGATTGGATTCTATTTCATCTTTTGATGTGACTT
TTCACTAGTTTACAAAAAAAAGGTTGGTGGTCAACAAAAAAAGCAAGTCATAGCAGTTCAGTGCCTTTGTTGGTAGTTTTTAACTTTTTT
TGTGATTCTTTTTGGAAAATCATAGCTTACAGATGGTATAACTGTATTATATAATGGAATTTTCTTTAGGTGTGGGAAAACTTGATCTGA
AAGAAAATTATCAGCTTCAATTGGCGATTGATTCAGTGCCCACAATGTAAACAGGGTTGGTAGTTGTTACTCATTTTGAATATACCTTTT
CCTTATTGTATTCTGTAATATAGGATCCTGGAAATGAGACCTGGTGGAATATTATTTTCAACTGTAGTCTTTCTATACTGTGGACTAATG

>101403_101403_5_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000458360_GNAI3_chr1_110116358_ENST00000369851_length(amino acids)=343AA_BP=28
MHPQSLAEEEIKTEQEVVEGMDISTRSKGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARA
DDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTF
KDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRS

--------------------------------------------------------------
>101403_101403_6_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000461685_GNAI3_chr1_110116358_ENST00000369851_length(transcript)=3063nt_BP=85nt
ATGCATCCACAGAGCTTGGCTGAAGAGGAAATAAAAACAGAACAGGAGGTGGTAGAGGGCATGGATATCTCTACTCGCTCCAAAGGTGCT
GGAGAATCTGGTAAAAGCACCATTGTGAAACAGATGAAAATCATTCATGAGGATGGCTATTCAGAGGATGAATGTAAACAATATAAAGTA
GTTGTCTACAGCAATACTATACAGTCCATCATTGCAATCATAAGAGCCATGGGACGGCTAAAGATTGACTTTGGGGAAGCTGCCAGGGCA
GATGATGCCCGGCAATTATTTGTTTTAGCTGGCAGTGCTGAAGAAGGAGTCATGACTCCAGAACTAGCAGGAGTGATTAAACGGTTATGG
CGAGATGGTGGGGTACAAGCTTGCTTCAGCAGATCCAGGGAATATCAGCTCAATGATTCTGCTTCATATTATCTAAATGATCTGGATAGA
ATATCCCAGTCTAACTACATTCCAACTCAGCAAGATGTTCTTCGGACGAGAGTGAAGACCACAGGCATTGTAGAAACACATTTCACCTTC
AAAGACCTATACTTCAAGATGTTTGATGTAGGTGGCCAAAGATCAGAACGAAAAAAGTGGATTCACTGTTTTGAGGGAGTGACAGCAATT
ATCTTCTGTGTGGCCCTCAGTGATTATGACCTTGTTCTGGCTGAGGACGAGGAGATGAACCGAATGCATGAAAGCATGAAACTGTTTGAC
AGCATTTGTAATAACAAATGGTTTACAGAAACTTCAATCATTCTCTTCCTTAACAAGAAAGACCTTTTTGAGGAAAAAATAAAGAGGAGT
CCGTTAACTATCTGTTATCCAGAATACACAGGTTCCAATACATATGAAGAGGCAGCTGCCTATATTCAATGCCAGTTTGAAGATCTGAAC
AGAAGAAAAGATACCAAGGAGATCTATACTCACTTCACCTGTGCCACAGACACGAAGAATGTGCAGTTTGTTTTTGATGCTGTTACAGAT
GTCATCATTAAAAACAACTTAAAGGAATGTGGACTTTATTGAGAAGCATGGATGTTAGTGAAAGTTACTACAGTGTGGAGTGTTGAGACC
AGACACCTTTTGCTGTCTCATGGGGCAGCTACAAGCATGAACGGGACCAGGGAATGGCAGCAGCATGCAGAATCTTAGCACTCTTTAGCA
CAATATTTTGTATTAGGGAACTTTTAATTGACATGAGATGCTAAAGTCAGACATTGGAATTGGAAGAACTATAAAGTGTGATTCGATCGT
CAAGACATCACTTGGATTTCTTAATCTTAAATGCTTATGGAAGATGTGAAGTTGAGGTGCTGCATTCTAGAACTTCAATATGTAGCTTAC
TCTTTTTTTCCCCCCTTCTTAAACCACCAGTGGTTCATTTTTAAGGTTTTTTCATCAAGAGAAGAATAACTTTACTAAATTTTATTTCTT
TATTTGCAAAAGAATCTTTATTAAAACAAACAATCTTAACTATGCACATGATGTGACCAGATCATCTTGAAAATATTCCTCTTTAGTAGG
AACTCTTTGTTTTTAACTCTTGGTATGGTCAGAATATAATACTTCCATAATTACTTATAATTCTTTCCGGTTACTGGGGCTATAAATACA
ACTTTTTAAATGAAATTTATGTTATTATCCTGCTCAAAGTACCATTATGGTTTCCATATGGTAATTACATTGGAAAGTTCTGCAATAAGA
TTCTAGTTCTCTCTTTTCTTTAAGCTTATGGTTGAAGGTTAACCTTGTTTGTGCAGATTACCAAATTACTGCTGATGTAGTATGATAAAG
TCAGCTTCTTGGATACAGACACACCCAGGGCAGCTGCCAATCAGAAATGCAAATTGCTAAATTCCAAACAGAACCAGTGACTTTGCTGCT
ACATATTTACTAAATTGACCACTTTGATTCTTGCTTGTTTGTCTCAGTTATAGGGAGTTTTGTACATGGTGCCTCTTGTTTTCCATCTTC
ATGGCCTTTTCTGTTGAGAAACATCTAAAGTGTATTAACAGTGCATGCTTTTACTTTGTAAATGTGGTGCCAAATCCCTGTTTGCCATCG
TTTTTACTGTACCGATGTTAACTGTAGTAATCCTTAGCCAGTATGTTCTTTTGCTGAAACTGTTGCATTTTGGGACTTTTTTCCACTTTG
TCATGTGTACATTTTTAATCTGTTATAGTTGGCGGCAGTATTAAAATGGTGAGTAAAGAGCCCAGGTTTGCTCCTGTTTGTAACTAGTCT
TTTCTGGAAATACTGTCTTCTGTTTCCTTTTGCCTTTGCAGAATGTGCTTTAGCCTTTGTCTGAGAATGGGTTTAGGTAGAAGGGTTTCC
TGAAAGTCTAGTCTTTTGGTGTAATAGTATTGTTGAACCTTAGGTTTTATGTTATATCTGCATATGAGTGATATGTGATCATGATTCATT
TTGCAGATTTACATTTTGCTTGTGTGGAAAGTTACGTTCACTTCAACCTACAGACCCTTTTGTATAATGTACAGCAAATGTCATTAAATA
TTGAATGCTCTATTGGGGGAAGACAAATGAAGAGAATGCATTTTGAGCATTTCAAATCAGTAGTTTGGGCAGTGCCTTTTGGGGTCCAAT
CTTTTTGGATTGGATTCTATTTCATCTTTTGATGTGACTTTTCACTAGTTTACAAAAAAAAGGTTGGTGGTCAACAAAAAAAGCAAGTCA
TAGCAGTTCAGTGCCTTTGTTGGTAGTTTTTAACTTTTTTTGTGATTCTTTTTGGAAAATCATAGCTTACAGATGGTATAACTGTATTAT
ATAATGGAATTTTCTTTAGGTGTGGGAAAACTTGATCTGAAAGAAAATTATCAGCTTCAATTGGCGATTGATTCAGTGCCCACAATGTAA
ACAGGGTTGGTAGTTGTTACTCATTTTGAATATACCTTTTCCTTATTGTATTCTGTAATATAGGATCCTGGAAATGAGACCTGGTGGAAT
ATTATTTTCAACTGTAGTCTTTCTATACTGTGGACTAATGAAATGGTGTTGTTGATAATCTAAAATAACCAATAATCCAAAAAAGTTCAT

>101403_101403_6_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000461685_GNAI3_chr1_110116358_ENST00000369851_length(amino acids)=343AA_BP=28
MHPQSLAEEEIKTEQEVVEGMDISTRSKGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARA
DDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTF
KDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRS

--------------------------------------------------------------
>101403_101403_7_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000471951_GNAI3_chr1_110116358_ENST00000369851_length(transcript)=3090nt_BP=112nt
AAGTATTGACATTACACAGTGTTAACAATGCATCCACAGAGCTTGGCTGAAGAGGAAATAAAAACAGAACAGGAGGTGGTAGAGGGCATG
GATATCTCTACTCGCTCCAAAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAACAGATGAAAATCATTCATGAGGATGGCTATTCA
GAGGATGAATGTAAACAATATAAAGTAGTTGTCTACAGCAATACTATACAGTCCATCATTGCAATCATAAGAGCCATGGGACGGCTAAAG
ATTGACTTTGGGGAAGCTGCCAGGGCAGATGATGCCCGGCAATTATTTGTTTTAGCTGGCAGTGCTGAAGAAGGAGTCATGACTCCAGAA
CTAGCAGGAGTGATTAAACGGTTATGGCGAGATGGTGGGGTACAAGCTTGCTTCAGCAGATCCAGGGAATATCAGCTCAATGATTCTGCT
TCATATTATCTAAATGATCTGGATAGAATATCCCAGTCTAACTACATTCCAACTCAGCAAGATGTTCTTCGGACGAGAGTGAAGACCACA
GGCATTGTAGAAACACATTTCACCTTCAAAGACCTATACTTCAAGATGTTTGATGTAGGTGGCCAAAGATCAGAACGAAAAAAGTGGATT
CACTGTTTTGAGGGAGTGACAGCAATTATCTTCTGTGTGGCCCTCAGTGATTATGACCTTGTTCTGGCTGAGGACGAGGAGATGAACCGA
ATGCATGAAAGCATGAAACTGTTTGACAGCATTTGTAATAACAAATGGTTTACAGAAACTTCAATCATTCTCTTCCTTAACAAGAAAGAC
CTTTTTGAGGAAAAAATAAAGAGGAGTCCGTTAACTATCTGTTATCCAGAATACACAGGTTCCAATACATATGAAGAGGCAGCTGCCTAT
ATTCAATGCCAGTTTGAAGATCTGAACAGAAGAAAAGATACCAAGGAGATCTATACTCACTTCACCTGTGCCACAGACACGAAGAATGTG
CAGTTTGTTTTTGATGCTGTTACAGATGTCATCATTAAAAACAACTTAAAGGAATGTGGACTTTATTGAGAAGCATGGATGTTAGTGAAA
GTTACTACAGTGTGGAGTGTTGAGACCAGACACCTTTTGCTGTCTCATGGGGCAGCTACAAGCATGAACGGGACCAGGGAATGGCAGCAG
CATGCAGAATCTTAGCACTCTTTAGCACAATATTTTGTATTAGGGAACTTTTAATTGACATGAGATGCTAAAGTCAGACATTGGAATTGG
AAGAACTATAAAGTGTGATTCGATCGTCAAGACATCACTTGGATTTCTTAATCTTAAATGCTTATGGAAGATGTGAAGTTGAGGTGCTGC
ATTCTAGAACTTCAATATGTAGCTTACTCTTTTTTTCCCCCCTTCTTAAACCACCAGTGGTTCATTTTTAAGGTTTTTTCATCAAGAGAA
GAATAACTTTACTAAATTTTATTTCTTTATTTGCAAAAGAATCTTTATTAAAACAAACAATCTTAACTATGCACATGATGTGACCAGATC
ATCTTGAAAATATTCCTCTTTAGTAGGAACTCTTTGTTTTTAACTCTTGGTATGGTCAGAATATAATACTTCCATAATTACTTATAATTC
TTTCCGGTTACTGGGGCTATAAATACAACTTTTTAAATGAAATTTATGTTATTATCCTGCTCAAAGTACCATTATGGTTTCCATATGGTA
ATTACATTGGAAAGTTCTGCAATAAGATTCTAGTTCTCTCTTTTCTTTAAGCTTATGGTTGAAGGTTAACCTTGTTTGTGCAGATTACCA
AATTACTGCTGATGTAGTATGATAAAGTCAGCTTCTTGGATACAGACACACCCAGGGCAGCTGCCAATCAGAAATGCAAATTGCTAAATT
CCAAACAGAACCAGTGACTTTGCTGCTACATATTTACTAAATTGACCACTTTGATTCTTGCTTGTTTGTCTCAGTTATAGGGAGTTTTGT
ACATGGTGCCTCTTGTTTTCCATCTTCATGGCCTTTTCTGTTGAGAAACATCTAAAGTGTATTAACAGTGCATGCTTTTACTTTGTAAAT
GTGGTGCCAAATCCCTGTTTGCCATCGTTTTTACTGTACCGATGTTAACTGTAGTAATCCTTAGCCAGTATGTTCTTTTGCTGAAACTGT
TGCATTTTGGGACTTTTTTCCACTTTGTCATGTGTACATTTTTAATCTGTTATAGTTGGCGGCAGTATTAAAATGGTGAGTAAAGAGCCC
AGGTTTGCTCCTGTTTGTAACTAGTCTTTTCTGGAAATACTGTCTTCTGTTTCCTTTTGCCTTTGCAGAATGTGCTTTAGCCTTTGTCTG
AGAATGGGTTTAGGTAGAAGGGTTTCCTGAAAGTCTAGTCTTTTGGTGTAATAGTATTGTTGAACCTTAGGTTTTATGTTATATCTGCAT
ATGAGTGATATGTGATCATGATTCATTTTGCAGATTTACATTTTGCTTGTGTGGAAAGTTACGTTCACTTCAACCTACAGACCCTTTTGT
ATAATGTACAGCAAATGTCATTAAATATTGAATGCTCTATTGGGGGAAGACAAATGAAGAGAATGCATTTTGAGCATTTCAAATCAGTAG
TTTGGGCAGTGCCTTTTGGGGTCCAATCTTTTTGGATTGGATTCTATTTCATCTTTTGATGTGACTTTTCACTAGTTTACAAAAAAAAGG
TTGGTGGTCAACAAAAAAAGCAAGTCATAGCAGTTCAGTGCCTTTGTTGGTAGTTTTTAACTTTTTTTGTGATTCTTTTTGGAAAATCAT
AGCTTACAGATGGTATAACTGTATTATATAATGGAATTTTCTTTAGGTGTGGGAAAACTTGATCTGAAAGAAAATTATCAGCTTCAATTG
GCGATTGATTCAGTGCCCACAATGTAAACAGGGTTGGTAGTTGTTACTCATTTTGAATATACCTTTTCCTTATTGTATTCTGTAATATAG
GATCCTGGAAATGAGACCTGGTGGAATATTATTTTCAACTGTAGTCTTTCTATACTGTGGACTAATGAAATGGTGTTGTTGATAATCTAA

>101403_101403_7_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000471951_GNAI3_chr1_110116358_ENST00000369851_length(amino acids)=343AA_BP=28
MHPQSLAEEEIKTEQEVVEGMDISTRSKGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARA
DDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTF
KDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRS

--------------------------------------------------------------
>101403_101403_8_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000536340_GNAI3_chr1_110116358_ENST00000369851_length(transcript)=3166nt_BP=188nt
GTCACATGGCTCAGTAGCCATTAGCCATAGCTTGATTTTGCAAACTGGCAAGGGCCTGGCACACCTTTCCTTCCACCAGGGCATGGTGTT
TCTGGAAGAGTTTGAAGCTAGATCCTGCTTGGCTGAAGAGGAAATAAAAACAGAACAGGAGGTGGTAGAGGGCATGGATATCTCTACTCG
CTCCAAAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAACAGATGAAAATCATTCATGAGGATGGCTATTCAGAGGATGAATGTAA
ACAATATAAAGTAGTTGTCTACAGCAATACTATACAGTCCATCATTGCAATCATAAGAGCCATGGGACGGCTAAAGATTGACTTTGGGGA
AGCTGCCAGGGCAGATGATGCCCGGCAATTATTTGTTTTAGCTGGCAGTGCTGAAGAAGGAGTCATGACTCCAGAACTAGCAGGAGTGAT
TAAACGGTTATGGCGAGATGGTGGGGTACAAGCTTGCTTCAGCAGATCCAGGGAATATCAGCTCAATGATTCTGCTTCATATTATCTAAA
TGATCTGGATAGAATATCCCAGTCTAACTACATTCCAACTCAGCAAGATGTTCTTCGGACGAGAGTGAAGACCACAGGCATTGTAGAAAC
ACATTTCACCTTCAAAGACCTATACTTCAAGATGTTTGATGTAGGTGGCCAAAGATCAGAACGAAAAAAGTGGATTCACTGTTTTGAGGG
AGTGACAGCAATTATCTTCTGTGTGGCCCTCAGTGATTATGACCTTGTTCTGGCTGAGGACGAGGAGATGAACCGAATGCATGAAAGCAT
GAAACTGTTTGACAGCATTTGTAATAACAAATGGTTTACAGAAACTTCAATCATTCTCTTCCTTAACAAGAAAGACCTTTTTGAGGAAAA
AATAAAGAGGAGTCCGTTAACTATCTGTTATCCAGAATACACAGGTTCCAATACATATGAAGAGGCAGCTGCCTATATTCAATGCCAGTT
TGAAGATCTGAACAGAAGAAAAGATACCAAGGAGATCTATACTCACTTCACCTGTGCCACAGACACGAAGAATGTGCAGTTTGTTTTTGA
TGCTGTTACAGATGTCATCATTAAAAACAACTTAAAGGAATGTGGACTTTATTGAGAAGCATGGATGTTAGTGAAAGTTACTACAGTGTG
GAGTGTTGAGACCAGACACCTTTTGCTGTCTCATGGGGCAGCTACAAGCATGAACGGGACCAGGGAATGGCAGCAGCATGCAGAATCTTA
GCACTCTTTAGCACAATATTTTGTATTAGGGAACTTTTAATTGACATGAGATGCTAAAGTCAGACATTGGAATTGGAAGAACTATAAAGT
GTGATTCGATCGTCAAGACATCACTTGGATTTCTTAATCTTAAATGCTTATGGAAGATGTGAAGTTGAGGTGCTGCATTCTAGAACTTCA
ATATGTAGCTTACTCTTTTTTTCCCCCCTTCTTAAACCACCAGTGGTTCATTTTTAAGGTTTTTTCATCAAGAGAAGAATAACTTTACTA
AATTTTATTTCTTTATTTGCAAAAGAATCTTTATTAAAACAAACAATCTTAACTATGCACATGATGTGACCAGATCATCTTGAAAATATT
CCTCTTTAGTAGGAACTCTTTGTTTTTAACTCTTGGTATGGTCAGAATATAATACTTCCATAATTACTTATAATTCTTTCCGGTTACTGG
GGCTATAAATACAACTTTTTAAATGAAATTTATGTTATTATCCTGCTCAAAGTACCATTATGGTTTCCATATGGTAATTACATTGGAAAG
TTCTGCAATAAGATTCTAGTTCTCTCTTTTCTTTAAGCTTATGGTTGAAGGTTAACCTTGTTTGTGCAGATTACCAAATTACTGCTGATG
TAGTATGATAAAGTCAGCTTCTTGGATACAGACACACCCAGGGCAGCTGCCAATCAGAAATGCAAATTGCTAAATTCCAAACAGAACCAG
TGACTTTGCTGCTACATATTTACTAAATTGACCACTTTGATTCTTGCTTGTTTGTCTCAGTTATAGGGAGTTTTGTACATGGTGCCTCTT
GTTTTCCATCTTCATGGCCTTTTCTGTTGAGAAACATCTAAAGTGTATTAACAGTGCATGCTTTTACTTTGTAAATGTGGTGCCAAATCC
CTGTTTGCCATCGTTTTTACTGTACCGATGTTAACTGTAGTAATCCTTAGCCAGTATGTTCTTTTGCTGAAACTGTTGCATTTTGGGACT
TTTTTCCACTTTGTCATGTGTACATTTTTAATCTGTTATAGTTGGCGGCAGTATTAAAATGGTGAGTAAAGAGCCCAGGTTTGCTCCTGT
TTGTAACTAGTCTTTTCTGGAAATACTGTCTTCTGTTTCCTTTTGCCTTTGCAGAATGTGCTTTAGCCTTTGTCTGAGAATGGGTTTAGG
TAGAAGGGTTTCCTGAAAGTCTAGTCTTTTGGTGTAATAGTATTGTTGAACCTTAGGTTTTATGTTATATCTGCATATGAGTGATATGTG
ATCATGATTCATTTTGCAGATTTACATTTTGCTTGTGTGGAAAGTTACGTTCACTTCAACCTACAGACCCTTTTGTATAATGTACAGCAA
ATGTCATTAAATATTGAATGCTCTATTGGGGGAAGACAAATGAAGAGAATGCATTTTGAGCATTTCAAATCAGTAGTTTGGGCAGTGCCT
TTTGGGGTCCAATCTTTTTGGATTGGATTCTATTTCATCTTTTGATGTGACTTTTCACTAGTTTACAAAAAAAAGGTTGGTGGTCAACAA
AAAAAGCAAGTCATAGCAGTTCAGTGCCTTTGTTGGTAGTTTTTAACTTTTTTTGTGATTCTTTTTGGAAAATCATAGCTTACAGATGGT
ATAACTGTATTATATAATGGAATTTTCTTTAGGTGTGGGAAAACTTGATCTGAAAGAAAATTATCAGCTTCAATTGGCGATTGATTCAGT
GCCCACAATGTAAACAGGGTTGGTAGTTGTTACTCATTTTGAATATACCTTTTCCTTATTGTATTCTGTAATATAGGATCCTGGAAATGA
GACCTGGTGGAATATTATTTTCAACTGTAGTCTTTCTATACTGTGGACTAATGAAATGGTGTTGTTGATAATCTAAAATAACCAATAATC

>101403_101403_8_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000536340_GNAI3_chr1_110116358_ENST00000369851_length(amino acids)=367AA_BP=52
MILQTGKGLAHLSFHQGMVFLEEFEARSCLAEEEIKTEQEVVEGMDISTRSKGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNT
IQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNY
IPTQQDVLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNK
WFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAAYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNN

--------------------------------------------------------------
>101403_101403_9_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000540497_GNAI3_chr1_110116358_ENST00000369851_length(transcript)=3063nt_BP=85nt
ATGCATCCACAGAGCTTGGCTGAAGAGGAAATAAAAACAGAACAGGAGGTGGTAGAGGGCATGGATATCTCTACTCGCTCCAAAGGTGCT
GGAGAATCTGGTAAAAGCACCATTGTGAAACAGATGAAAATCATTCATGAGGATGGCTATTCAGAGGATGAATGTAAACAATATAAAGTA
GTTGTCTACAGCAATACTATACAGTCCATCATTGCAATCATAAGAGCCATGGGACGGCTAAAGATTGACTTTGGGGAAGCTGCCAGGGCA
GATGATGCCCGGCAATTATTTGTTTTAGCTGGCAGTGCTGAAGAAGGAGTCATGACTCCAGAACTAGCAGGAGTGATTAAACGGTTATGG
CGAGATGGTGGGGTACAAGCTTGCTTCAGCAGATCCAGGGAATATCAGCTCAATGATTCTGCTTCATATTATCTAAATGATCTGGATAGA
ATATCCCAGTCTAACTACATTCCAACTCAGCAAGATGTTCTTCGGACGAGAGTGAAGACCACAGGCATTGTAGAAACACATTTCACCTTC
AAAGACCTATACTTCAAGATGTTTGATGTAGGTGGCCAAAGATCAGAACGAAAAAAGTGGATTCACTGTTTTGAGGGAGTGACAGCAATT
ATCTTCTGTGTGGCCCTCAGTGATTATGACCTTGTTCTGGCTGAGGACGAGGAGATGAACCGAATGCATGAAAGCATGAAACTGTTTGAC
AGCATTTGTAATAACAAATGGTTTACAGAAACTTCAATCATTCTCTTCCTTAACAAGAAAGACCTTTTTGAGGAAAAAATAAAGAGGAGT
CCGTTAACTATCTGTTATCCAGAATACACAGGTTCCAATACATATGAAGAGGCAGCTGCCTATATTCAATGCCAGTTTGAAGATCTGAAC
AGAAGAAAAGATACCAAGGAGATCTATACTCACTTCACCTGTGCCACAGACACGAAGAATGTGCAGTTTGTTTTTGATGCTGTTACAGAT
GTCATCATTAAAAACAACTTAAAGGAATGTGGACTTTATTGAGAAGCATGGATGTTAGTGAAAGTTACTACAGTGTGGAGTGTTGAGACC
AGACACCTTTTGCTGTCTCATGGGGCAGCTACAAGCATGAACGGGACCAGGGAATGGCAGCAGCATGCAGAATCTTAGCACTCTTTAGCA
CAATATTTTGTATTAGGGAACTTTTAATTGACATGAGATGCTAAAGTCAGACATTGGAATTGGAAGAACTATAAAGTGTGATTCGATCGT
CAAGACATCACTTGGATTTCTTAATCTTAAATGCTTATGGAAGATGTGAAGTTGAGGTGCTGCATTCTAGAACTTCAATATGTAGCTTAC
TCTTTTTTTCCCCCCTTCTTAAACCACCAGTGGTTCATTTTTAAGGTTTTTTCATCAAGAGAAGAATAACTTTACTAAATTTTATTTCTT
TATTTGCAAAAGAATCTTTATTAAAACAAACAATCTTAACTATGCACATGATGTGACCAGATCATCTTGAAAATATTCCTCTTTAGTAGG
AACTCTTTGTTTTTAACTCTTGGTATGGTCAGAATATAATACTTCCATAATTACTTATAATTCTTTCCGGTTACTGGGGCTATAAATACA
ACTTTTTAAATGAAATTTATGTTATTATCCTGCTCAAAGTACCATTATGGTTTCCATATGGTAATTACATTGGAAAGTTCTGCAATAAGA
TTCTAGTTCTCTCTTTTCTTTAAGCTTATGGTTGAAGGTTAACCTTGTTTGTGCAGATTACCAAATTACTGCTGATGTAGTATGATAAAG
TCAGCTTCTTGGATACAGACACACCCAGGGCAGCTGCCAATCAGAAATGCAAATTGCTAAATTCCAAACAGAACCAGTGACTTTGCTGCT
ACATATTTACTAAATTGACCACTTTGATTCTTGCTTGTTTGTCTCAGTTATAGGGAGTTTTGTACATGGTGCCTCTTGTTTTCCATCTTC
ATGGCCTTTTCTGTTGAGAAACATCTAAAGTGTATTAACAGTGCATGCTTTTACTTTGTAAATGTGGTGCCAAATCCCTGTTTGCCATCG
TTTTTACTGTACCGATGTTAACTGTAGTAATCCTTAGCCAGTATGTTCTTTTGCTGAAACTGTTGCATTTTGGGACTTTTTTCCACTTTG
TCATGTGTACATTTTTAATCTGTTATAGTTGGCGGCAGTATTAAAATGGTGAGTAAAGAGCCCAGGTTTGCTCCTGTTTGTAACTAGTCT
TTTCTGGAAATACTGTCTTCTGTTTCCTTTTGCCTTTGCAGAATGTGCTTTAGCCTTTGTCTGAGAATGGGTTTAGGTAGAAGGGTTTCC
TGAAAGTCTAGTCTTTTGGTGTAATAGTATTGTTGAACCTTAGGTTTTATGTTATATCTGCATATGAGTGATATGTGATCATGATTCATT
TTGCAGATTTACATTTTGCTTGTGTGGAAAGTTACGTTCACTTCAACCTACAGACCCTTTTGTATAATGTACAGCAAATGTCATTAAATA
TTGAATGCTCTATTGGGGGAAGACAAATGAAGAGAATGCATTTTGAGCATTTCAAATCAGTAGTTTGGGCAGTGCCTTTTGGGGTCCAAT
CTTTTTGGATTGGATTCTATTTCATCTTTTGATGTGACTTTTCACTAGTTTACAAAAAAAAGGTTGGTGGTCAACAAAAAAAGCAAGTCA
TAGCAGTTCAGTGCCTTTGTTGGTAGTTTTTAACTTTTTTTGTGATTCTTTTTGGAAAATCATAGCTTACAGATGGTATAACTGTATTAT
ATAATGGAATTTTCTTTAGGTGTGGGAAAACTTGATCTGAAAGAAAATTATCAGCTTCAATTGGCGATTGATTCAGTGCCCACAATGTAA
ACAGGGTTGGTAGTTGTTACTCATTTTGAATATACCTTTTCCTTATTGTATTCTGTAATATAGGATCCTGGAAATGAGACCTGGTGGAAT
ATTATTTTCAACTGTAGTCTTTCTATACTGTGGACTAATGAAATGGTGTTGTTGATAATCTAAAATAACCAATAATCCAAAAAAGTTCAT

>101403_101403_9_ZMYND8-GNAI3_ZMYND8_chr20_45976599_ENST00000540497_GNAI3_chr1_110116358_ENST00000369851_length(amino acids)=343AA_BP=28
MHPQSLAEEEIKTEQEVVEGMDISTRSKGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARA
DDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTF
KDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZMYND8-GNAI3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneZMYND8chr20:45976599chr1:110116358ENST00000262975-32475_4068.3333333333333341169.0histone H3K14ac
HgeneZMYND8chr20:45976599chr1:110116358ENST00000311275-22275_4068.3333333333333341187.0histone H3K14ac
HgeneZMYND8chr20:45976599chr1:110116358ENST00000352431-22275_40628.3333333333333321161.0histone H3K14ac
HgeneZMYND8chr20:45976599chr1:110116358ENST00000355972-32475_4068.3333333333333341215.0histone H3K14ac
HgeneZMYND8chr20:45976599chr1:110116358ENST00000360911-22275_40628.3333333333333321136.0histone H3K14ac
HgeneZMYND8chr20:45976599chr1:110116358ENST00000461685-22375_40628.3333333333333321189.0histone H3K14ac
HgeneZMYND8chr20:45976599chr1:110116358ENST00000471951-22375_40628.3333333333333321235.0histone H3K14ac
HgeneZMYND8chr20:45976599chr1:110116358ENST00000262975-32475_2688.3333333333333341169.0histone H3K4me0
HgeneZMYND8chr20:45976599chr1:110116358ENST00000311275-22275_2688.3333333333333341187.0histone H3K4me0
HgeneZMYND8chr20:45976599chr1:110116358ENST00000352431-22275_26828.3333333333333321161.0histone H3K4me0
HgeneZMYND8chr20:45976599chr1:110116358ENST00000355972-32475_2688.3333333333333341215.0histone H3K4me0
HgeneZMYND8chr20:45976599chr1:110116358ENST00000360911-22275_26828.3333333333333321136.0histone H3K4me0
HgeneZMYND8chr20:45976599chr1:110116358ENST00000461685-22375_26828.3333333333333321189.0histone H3K4me0
HgeneZMYND8chr20:45976599chr1:110116358ENST00000471951-22375_26828.3333333333333321235.0histone H3K4me0
HgeneZMYND8chr20:45976599chr1:110116358ENST00000262975-3241147_11868.3333333333333341169.0PRKCB1
HgeneZMYND8chr20:45976599chr1:110116358ENST00000311275-2221147_11868.3333333333333341187.0PRKCB1
HgeneZMYND8chr20:45976599chr1:110116358ENST00000352431-2221147_118628.3333333333333321161.0PRKCB1
HgeneZMYND8chr20:45976599chr1:110116358ENST00000355972-3241147_11868.3333333333333341215.0PRKCB1
HgeneZMYND8chr20:45976599chr1:110116358ENST00000360911-2221147_118628.3333333333333321136.0PRKCB1
HgeneZMYND8chr20:45976599chr1:110116358ENST00000461685-2231147_118628.3333333333333321189.0PRKCB1
HgeneZMYND8chr20:45976599chr1:110116358ENST00000471951-2231147_118628.3333333333333321235.0PRKCB1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZMYND8-GNAI3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZMYND8-GNAI3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource