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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF226-DDX19B (FusionGDB2 ID:101648)

Fusion Gene Summary for ZNF226-DDX19B

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF226-DDX19B
Fusion gene ID: 101648
HgeneTgene
Gene symbol

ZNF226

DDX19B

Gene ID

7769

11269

Gene namezinc finger protein 226DEAD-box helicase 19B
Synonyms-DBP5|DDX19|RNAh
Cytomap

19q13.31

16q22.1

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 226Kruppel-associated box proteinATP-dependent RNA helicase DDX19BATP-dependent RNA helicase DDX19DEAD (Asp-Glu-Ala-As) box polypeptide 19BDEAD (Asp-Glu-Ala-Asp) box polypeptide 19BDEAD box protein 19BDEAD-box RNA helicase DEAD5DEAD-box protein 5DEAD/H (Asp-Glu-Ala-Asp/His) box po
Modification date2020031320200313
UniProtAcc.

Q9UMR2

Ensembl transtripts involved in fusion geneENST00000300823, ENST00000337433, 
ENST00000413984, ENST00000454662, 
ENST00000588742, ENST00000588795, 
ENST00000588883, ENST00000589160, 
ENST00000590089, 		ENST00000288071, 
ENST00000355992, ENST00000393657, 
ENST00000451014, ENST00000563206, 
ENST00000568625, ENST00000570055, 
ENST00000563392, 
Fusion gene scores* DoF score4 X 2 X 4=327 X 9 X 8=504
# samples 413
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(13/504*10)=-1.95491211047146
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF226 [Title/Abstract] AND DDX19B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF226(44677105)-DDX19B(70366870), # samples:1
Anticipated loss of major functional domain due to fusion event.ZNF226-DDX19B seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
ZNF226-DDX19B seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ZNF226 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DDX19B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-IG-A3YCZNF226chr19

44677105

+DDX19Bchr16

70366870

+


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Fusion Gene ORF analysis for ZNF226-DDX19B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000300823ENST00000288071ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000300823ENST00000355992ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000300823ENST00000393657ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000300823ENST00000451014ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000300823ENST00000563206ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000300823ENST00000568625ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000300823ENST00000570055ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000337433ENST00000288071ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000337433ENST00000355992ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000337433ENST00000393657ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000337433ENST00000451014ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000337433ENST00000563206ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000337433ENST00000568625ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000337433ENST00000570055ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000413984ENST00000288071ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000413984ENST00000355992ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000413984ENST00000393657ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000413984ENST00000451014ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000413984ENST00000563206ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000413984ENST00000568625ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000413984ENST00000570055ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000454662ENST00000288071ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000454662ENST00000355992ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000454662ENST00000393657ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000454662ENST00000451014ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000454662ENST00000563206ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000454662ENST00000568625ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000454662ENST00000570055ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588742ENST00000288071ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588742ENST00000355992ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588742ENST00000393657ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588742ENST00000451014ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588742ENST00000563206ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588742ENST00000568625ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588742ENST00000570055ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588795ENST00000288071ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588795ENST00000355992ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588795ENST00000393657ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588795ENST00000451014ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588795ENST00000563206ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588795ENST00000568625ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588795ENST00000570055ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588883ENST00000288071ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588883ENST00000355992ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588883ENST00000393657ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588883ENST00000451014ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588883ENST00000563206ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588883ENST00000568625ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000588883ENST00000570055ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000589160ENST00000288071ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000589160ENST00000355992ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000589160ENST00000393657ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000589160ENST00000451014ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000589160ENST00000563206ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000589160ENST00000568625ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000589160ENST00000570055ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000590089ENST00000288071ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000590089ENST00000355992ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000590089ENST00000393657ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000590089ENST00000451014ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000590089ENST00000563206ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000590089ENST00000568625ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
5CDS-intronENST00000590089ENST00000570055ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
Frame-shiftENST00000588883ENST00000563392ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
Frame-shiftENST00000589160ENST00000563392ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
In-frameENST00000300823ENST00000563392ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
In-frameENST00000337433ENST00000563392ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
In-frameENST00000413984ENST00000563392ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
In-frameENST00000454662ENST00000563392ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
In-frameENST00000588742ENST00000563392ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
In-frameENST00000588795ENST00000563392ZNF226chr19

44677105

+DDX19Bchr16

70366870

+
In-frameENST00000590089ENST00000563392ZNF226chr19

44677105

+DDX19Bchr16

70366870

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000337433ZNF226chr1944677105+ENST00000563392DDX19Bchr1670366870+871379144632162
ENST00000413984ZNF226chr1944677105+ENST00000563392DDX19Bchr1670366870+1033541306794162
ENST00000588742ZNF226chr1944677105+ENST00000563392DDX19Bchr1670366870+889397162650162
ENST00000300823ZNF226chr1944677105+ENST00000563392DDX19Bchr1670366870+863371136624162
ENST00000588795ZNF226chr1944677105+ENST00000563392DDX19Bchr1670366870+1040548873514119
ENST00000590089ZNF226chr1944677105+ENST00000563392DDX19Bchr1670366870+1094602367855162
ENST00000454662ZNF226chr1944677105+ENST00000563392DDX19Bchr1670366870+907415180668162

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000337433ENST00000563392ZNF226chr1944677105+DDX19Bchr1670366870+0.0019049210.9980951
ENST00000413984ENST00000563392ZNF226chr1944677105+DDX19Bchr1670366870+0.0019113920.99808854
ENST00000588742ENST00000563392ZNF226chr1944677105+DDX19Bchr1670366870+0.0019742420.9980258
ENST00000300823ENST00000563392ZNF226chr1944677105+DDX19Bchr1670366870+0.0024717860.99752825
ENST00000588795ENST00000563392ZNF226chr1944677105+DDX19Bchr1670366870+0.15732750.84267247
ENST00000590089ENST00000563392ZNF226chr1944677105+DDX19Bchr1670366870+0.0030791730.9969208
ENST00000454662ENST00000563392ZNF226chr1944677105+DDX19Bchr1670366870+0.0024566460.99754333

Top

Fusion Genomic Features for ZNF226-DDX19B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNF226chr1944677105+DDX19Bchr1670366870+6.22E-050.9999378
ZNF226chr1944677105+DDX19Bchr1670366870+6.22E-050.9999378

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZNF226-DDX19B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:44677105/chr16:70366870)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DDX19B

Q9UMR2

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: ATP-dependent RNA helicase involved in mRNA export from the nucleus (PubMed:10428971). Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins (PubMed:10428971). {ECO:0000269|PubMed:10428971}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+568_787895.0DomainKRAB
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+568_7878804.0DomainKRAB
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+568_787895.0DomainKRAB
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+568_7878804.0DomainKRAB
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+678_787895.0DomainKRAB
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+678_7878804.0DomainKRAB
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000393657710306_474286371.0DomainHelicase C-terminal
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000563392710306_474286371.0DomainHelicase C-terminal
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000568625811306_474286371.0DomainHelicase C-terminal
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000393657710301_479286371.0RegionNote=C-terminal lobe
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000563392710301_479286371.0RegionNote=C-terminal lobe
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000568625811301_479286371.0RegionNote=C-terminal lobe

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56252_2747895.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56280_3027895.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56307_3297895.0Zinc fingerC2H2-type 3
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56335_3577895.0Zinc fingerC2H2-type 4
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56363_3857895.0Zinc fingerC2H2-type 5
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56391_4137895.0Zinc fingerC2H2-type 6
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56419_4417895.0Zinc fingerC2H2-type 7
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56447_4697895.0Zinc fingerC2H2-type 8
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56475_4977895.0Zinc fingerC2H2-type 9
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56503_5257895.0Zinc fingerC2H2-type 10
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56531_5537895.0Zinc fingerC2H2-type 11
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56559_5817895.0Zinc fingerC2H2-type 12
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56587_6097895.0Zinc fingerC2H2-type 13
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56615_6377895.0Zinc fingerC2H2-type 14
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56643_6657895.0Zinc fingerC2H2-type 15
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56671_6937895.0Zinc fingerC2H2-type 16
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56699_7217895.0Zinc fingerC2H2-type 17
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56727_7497895.0Zinc fingerC2H2-type 18
HgeneZNF226chr19:44677105chr16:70366870ENST00000300823+56755_7777895.0Zinc fingerC2H2-type 19
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56252_27478804.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56280_30278804.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56307_32978804.0Zinc fingerC2H2-type 3
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56335_35778804.0Zinc fingerC2H2-type 4
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56363_38578804.0Zinc fingerC2H2-type 5
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56391_41378804.0Zinc fingerC2H2-type 6
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56419_44178804.0Zinc fingerC2H2-type 7
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56447_46978804.0Zinc fingerC2H2-type 8
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56475_49778804.0Zinc fingerC2H2-type 9
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56503_52578804.0Zinc fingerC2H2-type 10
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56531_55378804.0Zinc fingerC2H2-type 11
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56559_58178804.0Zinc fingerC2H2-type 12
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56587_60978804.0Zinc fingerC2H2-type 13
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56615_63778804.0Zinc fingerC2H2-type 14
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56643_66578804.0Zinc fingerC2H2-type 15
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56671_69378804.0Zinc fingerC2H2-type 16
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56699_72178804.0Zinc fingerC2H2-type 17
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56727_74978804.0Zinc fingerC2H2-type 18
HgeneZNF226chr19:44677105chr16:70366870ENST00000337433+56755_77778804.0Zinc fingerC2H2-type 19
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56252_2747895.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56280_3027895.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56307_3297895.0Zinc fingerC2H2-type 3
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56335_3577895.0Zinc fingerC2H2-type 4
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56363_3857895.0Zinc fingerC2H2-type 5
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56391_4137895.0Zinc fingerC2H2-type 6
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56419_4417895.0Zinc fingerC2H2-type 7
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56447_4697895.0Zinc fingerC2H2-type 8
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56475_4977895.0Zinc fingerC2H2-type 9
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56503_5257895.0Zinc fingerC2H2-type 10
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56531_5537895.0Zinc fingerC2H2-type 11
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56559_5817895.0Zinc fingerC2H2-type 12
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56587_6097895.0Zinc fingerC2H2-type 13
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56615_6377895.0Zinc fingerC2H2-type 14
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56643_6657895.0Zinc fingerC2H2-type 15
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56671_6937895.0Zinc fingerC2H2-type 16
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56699_7217895.0Zinc fingerC2H2-type 17
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56727_7497895.0Zinc fingerC2H2-type 18
HgeneZNF226chr19:44677105chr16:70366870ENST00000413984+56755_7777895.0Zinc fingerC2H2-type 19
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56252_27478804.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56280_30278804.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56307_32978804.0Zinc fingerC2H2-type 3
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56335_35778804.0Zinc fingerC2H2-type 4
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56363_38578804.0Zinc fingerC2H2-type 5
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56391_41378804.0Zinc fingerC2H2-type 6
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56419_44178804.0Zinc fingerC2H2-type 7
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56447_46978804.0Zinc fingerC2H2-type 8
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56475_49778804.0Zinc fingerC2H2-type 9
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56503_52578804.0Zinc fingerC2H2-type 10
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56531_55378804.0Zinc fingerC2H2-type 11
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56559_58178804.0Zinc fingerC2H2-type 12
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56587_60978804.0Zinc fingerC2H2-type 13
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56615_63778804.0Zinc fingerC2H2-type 14
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56643_66578804.0Zinc fingerC2H2-type 15
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56671_69378804.0Zinc fingerC2H2-type 16
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56699_72178804.0Zinc fingerC2H2-type 17
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56727_74978804.0Zinc fingerC2H2-type 18
HgeneZNF226chr19:44677105chr16:70366870ENST00000454662+56755_77778804.0Zinc fingerC2H2-type 19
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67252_2747895.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67280_3027895.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67307_3297895.0Zinc fingerC2H2-type 3
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67335_3577895.0Zinc fingerC2H2-type 4
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67363_3857895.0Zinc fingerC2H2-type 5
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67391_4137895.0Zinc fingerC2H2-type 6
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67419_4417895.0Zinc fingerC2H2-type 7
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67447_4697895.0Zinc fingerC2H2-type 8
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67475_4977895.0Zinc fingerC2H2-type 9
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67503_5257895.0Zinc fingerC2H2-type 10
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67531_5537895.0Zinc fingerC2H2-type 11
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67559_5817895.0Zinc fingerC2H2-type 12
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67587_6097895.0Zinc fingerC2H2-type 13
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67615_6377895.0Zinc fingerC2H2-type 14
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67643_6657895.0Zinc fingerC2H2-type 15
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67671_6937895.0Zinc fingerC2H2-type 16
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67699_7217895.0Zinc fingerC2H2-type 17
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67727_7497895.0Zinc fingerC2H2-type 18
HgeneZNF226chr19:44677105chr16:70366870ENST00000588742+67755_7777895.0Zinc fingerC2H2-type 19
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67252_27478804.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67280_30278804.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67307_32978804.0Zinc fingerC2H2-type 3
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67335_35778804.0Zinc fingerC2H2-type 4
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67363_38578804.0Zinc fingerC2H2-type 5
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67391_41378804.0Zinc fingerC2H2-type 6
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67419_44178804.0Zinc fingerC2H2-type 7
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67447_46978804.0Zinc fingerC2H2-type 8
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67475_49778804.0Zinc fingerC2H2-type 9
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67503_52578804.0Zinc fingerC2H2-type 10
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67531_55378804.0Zinc fingerC2H2-type 11
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67559_58178804.0Zinc fingerC2H2-type 12
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67587_60978804.0Zinc fingerC2H2-type 13
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67615_63778804.0Zinc fingerC2H2-type 14
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67643_66578804.0Zinc fingerC2H2-type 15
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67671_69378804.0Zinc fingerC2H2-type 16
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67699_72178804.0Zinc fingerC2H2-type 17
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67727_74978804.0Zinc fingerC2H2-type 18
HgeneZNF226chr19:44677105chr16:70366870ENST00000590089+67755_77778804.0Zinc fingerC2H2-type 19
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000288071912125_295395480.0DomainHelicase ATP-binding
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000288071912306_474395480.0DomainHelicase C-terminal
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000355992811125_295364449.0DomainHelicase ATP-binding
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000355992811306_474364449.0DomainHelicase C-terminal
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000393657710125_295286371.0DomainHelicase ATP-binding
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000451014811125_295369454.0DomainHelicase ATP-binding
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000451014811306_474369454.0DomainHelicase C-terminal
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000563392710125_295286371.0DomainHelicase ATP-binding
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000568625811125_295286371.0DomainHelicase ATP-binding
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000288071912242_245395480.0MotifNote=DEAD box
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000028807191292_120395480.0MotifNote=Q motif
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000355992811242_245364449.0MotifNote=DEAD box
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000035599281192_120364449.0MotifNote=Q motif
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000393657710242_245286371.0MotifNote=DEAD box
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000039365771092_120286371.0MotifNote=Q motif
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000451014811242_245369454.0MotifNote=DEAD box
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000045101481192_120369454.0MotifNote=Q motif
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000563392710242_245286371.0MotifNote=DEAD box
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000056339271092_120286371.0MotifNote=Q motif
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000568625811242_245286371.0MotifNote=DEAD box
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000056862581192_120286371.0MotifNote=Q motif
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000288071912138_145395480.0Nucleotide bindingNote=ATP
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000355992811138_145364449.0Nucleotide bindingNote=ATP
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000393657710138_145286371.0Nucleotide bindingNote=ATP
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000451014811138_145369454.0Nucleotide bindingNote=ATP
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000563392710138_145286371.0Nucleotide bindingNote=ATP
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000568625811138_145286371.0Nucleotide bindingNote=ATP
TgeneDDX19Bchr19:44677105chr16:70366870ENST000002880719122_300395480.0RegionNote=N-terminal lobe
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000288071912301_479395480.0RegionNote=C-terminal lobe
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000028807191255_68395480.0RegionNote=N-terminal helix
TgeneDDX19Bchr19:44677105chr16:70366870ENST000003559928112_300364449.0RegionNote=N-terminal lobe
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000355992811301_479364449.0RegionNote=C-terminal lobe
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000035599281155_68364449.0RegionNote=N-terminal helix
TgeneDDX19Bchr19:44677105chr16:70366870ENST000003936577102_300286371.0RegionNote=N-terminal lobe
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000039365771055_68286371.0RegionNote=N-terminal helix
TgeneDDX19Bchr19:44677105chr16:70366870ENST000004510148112_300369454.0RegionNote=N-terminal lobe
TgeneDDX19Bchr19:44677105chr16:70366870ENST00000451014811301_479369454.0RegionNote=C-terminal lobe
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000045101481155_68369454.0RegionNote=N-terminal helix
TgeneDDX19Bchr19:44677105chr16:70366870ENST000005633927102_300286371.0RegionNote=N-terminal lobe
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000056339271055_68286371.0RegionNote=N-terminal helix
TgeneDDX19Bchr19:44677105chr16:70366870ENST000005686258112_300286371.0RegionNote=N-terminal lobe
TgeneDDX19Bchr19:44677105chr16:70366870ENST0000056862581155_68286371.0RegionNote=N-terminal helix


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Fusion Gene Sequence for ZNF226-DDX19B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>101648_101648_1_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000300823_DDX19B_chr16_70366870_ENST00000563392_length(transcript)=863nt_BP=371nt
GACGTAGCAGCCATCTTTTCCCTGGCTTTGGTGATTCAGCCCTGACTTCTCAAAAAGCACTGCACAGAGGAGGAGGCAGCAGAACCCCAT
TTCAGCTTCTTAGGACTCTGCACTTCCCCAGAAGGAAGAATTAAAAATGAATATGTTCAAGGAAGCAGTGACCTTCAAGGACGTGGCTGT
GGCCTTCACGGAGGAGGAATTGGGGCTGCTGGGCCCTGCCCAGAGGAAGCTGTACCGAGATGTGATGGTGGAGAACTTTAGGAACCTGCT
GTCAGTGGGGCATCCACCCTTCAAACAAGATGTATCACCTATAGAAAGAAATGAGCAGCTTTGGATAATGACGACAGCAACCCGAAGACA
GGGAAATTTAGGCATTGATGTTGAACAAGTGTCTGTCGTCATCAACTTTGATCTTCCCGTGGACAAGGACGGGAATCCTGACAATGAGAC
CTACCTGCACCGGATCGGGCGCACGGGCCGCTTTGGCAAGAGGGGCCTGGCAGTGAACATGGTGGACAGCAAGCACAGCATGAACATCCT
GAACAGAATCCAGGAGCATTTTAATAAGAAGATAGAAAGATTGGACACAGATGATTTGGACGAGATTGAGAAAATAGCCAACTGAGAAGC
TCCACCAGCCACTGATGCCAGCCCTGGCACTGCCCCTGCACAGGAGACAAGTGCGTTCAGGGCACAGGCCCCGACATCACCCCAAGGACA
ACGGCACAAGTAGAGAGAAACTACCTACCTCACTTCAAATTATGTTTGGACTTGACAAAAATGTATGCAAATGATGGGGGATGGTAGAAA

>101648_101648_1_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000300823_DDX19B_chr16_70366870_ENST00000563392_length(amino acids)=162AA_BP=78
MNMFKEAVTFKDVAVAFTEEELGLLGPAQRKLYRDVMVENFRNLLSVGHPPFKQDVSPIERNEQLWIMTTATRRQGNLGIDVEQVSVVIN

--------------------------------------------------------------
>101648_101648_2_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000337433_DDX19B_chr16_70366870_ENST00000563392_length(transcript)=871nt_BP=379nt
AGGAAGACGACGTAGCAGCCATCTTTTCCCTGGCTTTGGTGATTCAGCCCTGACTTCTCAAAAAGCACTGCACAGAGGAGGAGGCAGCAG
AACCCCATTTCAGCTTCTTAGGACTCTGCACTTCCCCAGAAGGAAGAATTAAAAATGAATATGTTCAAGGAAGCAGTGACCTTCAAGGAC
GTGGCTGTGGCCTTCACGGAGGAGGAATTGGGGCTGCTGGGCCCTGCCCAGAGGAAGCTGTACCGAGATGTGATGGTGGAGAACTTTAGG
AACCTGCTGTCAGTGGGGCATCCACCCTTCAAACAAGATGTATCACCTATAGAAAGAAATGAGCAGCTTTGGATAATGACGACAGCAACC
CGAAGACAGGGAAATTTAGGCATTGATGTTGAACAAGTGTCTGTCGTCATCAACTTTGATCTTCCCGTGGACAAGGACGGGAATCCTGAC
AATGAGACCTACCTGCACCGGATCGGGCGCACGGGCCGCTTTGGCAAGAGGGGCCTGGCAGTGAACATGGTGGACAGCAAGCACAGCATG
AACATCCTGAACAGAATCCAGGAGCATTTTAATAAGAAGATAGAAAGATTGGACACAGATGATTTGGACGAGATTGAGAAAATAGCCAAC
TGAGAAGCTCCACCAGCCACTGATGCCAGCCCTGGCACTGCCCCTGCACAGGAGACAAGTGCGTTCAGGGCACAGGCCCCGACATCACCC
CAAGGACAACGGCACAAGTAGAGAGAAACTACCTACCTCACTTCAAATTATGTTTGGACTTGACAAAAATGTATGCAAATGATGGGGGAT

>101648_101648_2_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000337433_DDX19B_chr16_70366870_ENST00000563392_length(amino acids)=162AA_BP=78
MNMFKEAVTFKDVAVAFTEEELGLLGPAQRKLYRDVMVENFRNLLSVGHPPFKQDVSPIERNEQLWIMTTATRRQGNLGIDVEQVSVVIN

--------------------------------------------------------------
>101648_101648_3_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000413984_DDX19B_chr16_70366870_ENST00000563392_length(transcript)=1033nt_BP=541nt
CGACGTAGCAGCCATCTTTTCCCTGGCTTTGGTGATTCAGAAACTCCCGTTCTGTGGCGAAATTCTGTGAGTCCATGAAGCTGGATTGTC
CCTGACCTCTTTTGAGGAAGGAGAGGGTTGCTTCTAACTGGTCCTGGGAGATGCCACTGTGATGTATCCGGGATGAAGACACAATCCTGG
TTACTTCATAGCCTGTTTTTCTTCCCCAGCCCTGACTTCTCAAAAAGCACTGCACAGAGGAGGAGGCAGCAGAACCCCATTTCAGCTTCT
TAGGACTCTGCACTTCCCCAGAAGGAAGAATTAAAAATGAATATGTTCAAGGAAGCAGTGACCTTCAAGGACGTGGCTGTGGCCTTCACG
GAGGAGGAATTGGGGCTGCTGGGCCCTGCCCAGAGGAAGCTGTACCGAGATGTGATGGTGGAGAACTTTAGGAACCTGCTGTCAGTGGGG
CATCCACCCTTCAAACAAGATGTATCACCTATAGAAAGAAATGAGCAGCTTTGGATAATGACGACAGCAACCCGAAGACAGGGAAATTTA
GGCATTGATGTTGAACAAGTGTCTGTCGTCATCAACTTTGATCTTCCCGTGGACAAGGACGGGAATCCTGACAATGAGACCTACCTGCAC
CGGATCGGGCGCACGGGCCGCTTTGGCAAGAGGGGCCTGGCAGTGAACATGGTGGACAGCAAGCACAGCATGAACATCCTGAACAGAATC
CAGGAGCATTTTAATAAGAAGATAGAAAGATTGGACACAGATGATTTGGACGAGATTGAGAAAATAGCCAACTGAGAAGCTCCACCAGCC
ACTGATGCCAGCCCTGGCACTGCCCCTGCACAGGAGACAAGTGCGTTCAGGGCACAGGCCCCGACATCACCCCAAGGACAACGGCACAAG
TAGAGAGAAACTACCTACCTCACTTCAAATTATGTTTGGACTTGACAAAAATGTATGCAAATGATGGGGGATGGTAGAAAAAAATTATTT

>101648_101648_3_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000413984_DDX19B_chr16_70366870_ENST00000563392_length(amino acids)=162AA_BP=78
MNMFKEAVTFKDVAVAFTEEELGLLGPAQRKLYRDVMVENFRNLLSVGHPPFKQDVSPIERNEQLWIMTTATRRQGNLGIDVEQVSVVIN

--------------------------------------------------------------
>101648_101648_4_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000454662_DDX19B_chr16_70366870_ENST00000563392_length(transcript)=907nt_BP=415nt
CAAACTTCCCCGAAATGCACTTGTGGTCAGCAGCTAGCGGTCTTTTGTTTGGGGAAAAAAAGGAGTAGCGGCTAAGAGCGGAGCCCTGAC
TTCTCAAAAAGCACTGCACAGAGGAGGAGGCAGCAGAACCCCATTTCAGCTTCTTAGGACTCTGCACTTCCCCAGAAGGAAGAATTAAAA
ATGAATATGTTCAAGGAAGCAGTGACCTTCAAGGACGTGGCTGTGGCCTTCACGGAGGAGGAATTGGGGCTGCTGGGCCCTGCCCAGAGG
AAGCTGTACCGAGATGTGATGGTGGAGAACTTTAGGAACCTGCTGTCAGTGGGGCATCCACCCTTCAAACAAGATGTATCACCTATAGAA
AGAAATGAGCAGCTTTGGATAATGACGACAGCAACCCGAAGACAGGGAAATTTAGGCATTGATGTTGAACAAGTGTCTGTCGTCATCAAC
TTTGATCTTCCCGTGGACAAGGACGGGAATCCTGACAATGAGACCTACCTGCACCGGATCGGGCGCACGGGCCGCTTTGGCAAGAGGGGC
CTGGCAGTGAACATGGTGGACAGCAAGCACAGCATGAACATCCTGAACAGAATCCAGGAGCATTTTAATAAGAAGATAGAAAGATTGGAC
ACAGATGATTTGGACGAGATTGAGAAAATAGCCAACTGAGAAGCTCCACCAGCCACTGATGCCAGCCCTGGCACTGCCCCTGCACAGGAG
ACAAGTGCGTTCAGGGCACAGGCCCCGACATCACCCCAAGGACAACGGCACAAGTAGAGAGAAACTACCTACCTCACTTCAAATTATGTT
TGGACTTGACAAAAATGTATGCAAATGATGGGGGATGGTAGAAAAAAATTATTTACACAACCTTGGAAGATTAGGCATGAATACACAGAG

>101648_101648_4_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000454662_DDX19B_chr16_70366870_ENST00000563392_length(amino acids)=162AA_BP=78
MNMFKEAVTFKDVAVAFTEEELGLLGPAQRKLYRDVMVENFRNLLSVGHPPFKQDVSPIERNEQLWIMTTATRRQGNLGIDVEQVSVVIN

--------------------------------------------------------------
>101648_101648_5_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000588742_DDX19B_chr16_70366870_ENST00000563392_length(transcript)=889nt_BP=397nt
GACGTAGCAGCCATCTTTTCCCTGGCTTTGGTGATTCAGAAACTCCCGTTCTGTGGCGAAATTCTCCCTGACTTCTCAAAAAGCACTGCA
CAGAGGAGGAGGCAGCAGAACCCCATTTCAGCTTCTTAGGACTCTGCACTTCCCCAGAAGGAAGAATTAAAAATGAATATGTTCAAGGAA
GCAGTGACCTTCAAGGACGTGGCTGTGGCCTTCACGGAGGAGGAATTGGGGCTGCTGGGCCCTGCCCAGAGGAAGCTGTACCGAGATGTG
ATGGTGGAGAACTTTAGGAACCTGCTGTCAGTGGGGCATCCACCCTTCAAACAAGATGTATCACCTATAGAAAGAAATGAGCAGCTTTGG
ATAATGACGACAGCAACCCGAAGACAGGGAAATTTAGGCATTGATGTTGAACAAGTGTCTGTCGTCATCAACTTTGATCTTCCCGTGGAC
AAGGACGGGAATCCTGACAATGAGACCTACCTGCACCGGATCGGGCGCACGGGCCGCTTTGGCAAGAGGGGCCTGGCAGTGAACATGGTG
GACAGCAAGCACAGCATGAACATCCTGAACAGAATCCAGGAGCATTTTAATAAGAAGATAGAAAGATTGGACACAGATGATTTGGACGAG
ATTGAGAAAATAGCCAACTGAGAAGCTCCACCAGCCACTGATGCCAGCCCTGGCACTGCCCCTGCACAGGAGACAAGTGCGTTCAGGGCA
CAGGCCCCGACATCACCCCAAGGACAACGGCACAAGTAGAGAGAAACTACCTACCTCACTTCAAATTATGTTTGGACTTGACAAAAATGT

>101648_101648_5_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000588742_DDX19B_chr16_70366870_ENST00000563392_length(amino acids)=162AA_BP=78
MNMFKEAVTFKDVAVAFTEEELGLLGPAQRKLYRDVMVENFRNLLSVGHPPFKQDVSPIERNEQLWIMTTATRRQGNLGIDVEQVSVVIN

--------------------------------------------------------------
>101648_101648_6_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000588795_DDX19B_chr16_70366870_ENST00000563392_length(transcript)=1040nt_BP=548nt
ATCTTTTCCCTGGCTTTGGTGATTCAGCCCTGACTTCTCAAAAAGCACTGCACAGAGGAGGAGGCAGCAGAACCCCATTTCAGCTTCTTA
GGACTCTGCACTTCCCCAGAAGGAAGAATTAAAAATGAATATGTTCAAGGAAGCAGTGACCTTCAAGGACGTGGCTGTGGCCTTCACGGA
GGAGGAATTGGGGCTGCTGGGCCCTGCCCAGAGGAAGCTGTACCGAGATGTGATGGTGGAGAACTTTAGGAACCTGCTGTCAGTGGGTAA
AAACCAAACAGTTATGAGTTCTTATAGTTAACTGTCCATCTGCTTTGCTTCTTCTTAGCCTTGTTGCCATCACCTGGTCCAAATTGCCAA
CTGTCTTTCCTGGATTATTGCAACACCCTTTGTACTGCTTGCCCTGCTCCCACCCCTCTCCTCTTACATTCTGTTCTTTAAGTGGCAAAG
TGAGTTTTTGTTACCTTGTGTCAGACTATGTTGTTCTTCTGCTCAAAATTCTCTGTGACTTATTTTACATAGAGTAAAATCCACTTAATG
TGGCTGACGCATTGATGTTGAACAAGTGTCTGTCGTCATCAACTTTGATCTTCCCGTGGACAAGGACGGGAATCCTGACAATGAGACCTA
CCTGCACCGGATCGGGCGCACGGGCCGCTTTGGCAAGAGGGGCCTGGCAGTGAACATGGTGGACAGCAAGCACAGCATGAACATCCTGAA
CAGAATCCAGGAGCATTTTAATAAGAAGATAGAAAGATTGGACACAGATGATTTGGACGAGATTGAGAAAATAGCCAACTGAGAAGCTCC
ACCAGCCACTGATGCCAGCCCTGGCACTGCCCCTGCACAGGAGACAAGTGCGTTCAGGGCACAGGCCCCGACATCACCCCAAGGACAACG
GCACAAGTAGAGAGAAACTACCTACCTCACTTCAAATTATGTTTGGACTTGACAAAAATGTATGCAAATGATGGGGGATGGTAGAAAAAA

>101648_101648_6_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000588795_DDX19B_chr16_70366870_ENST00000563392_length(amino acids)=119AA_BP=1
MCPERTCLLCRGSARAGISGWWSFSVGYFLNLVQIICVQSFYLLIKMLLDSVQDVHAVLAVHHVHCQAPLAKAARAPDPVQVGLIVRIPV

--------------------------------------------------------------
>101648_101648_7_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000590089_DDX19B_chr16_70366870_ENST00000563392_length(transcript)=1094nt_BP=602nt
GGAACCTTTCAAACTTCCCCGAAATGCACTTGTGGTCAGCAGCTAGCGGTCTTTTGTTTGGGGAAAAAAAGGAGTAGCGGCTAAGAGCGG
AGCCCTGACTTCTCAAAAAGCACTGCACAGAGGAGGAGGCAGCAGAACCCCATGGGCTGTTTTGGGAGAGGGACTGAGTACAGTGCAACA
CTACTCAAACTGTGGTTCACAAAGCAGCAACATTGGCATCACCCAGGTAGAAAGGCTCATTCTTGAGCCCTACCGAAGGCCTTCTGATTT
AGCATTTTTGCAGATAGGACCCAGAAATCTGCATTTCAACAAGATCCCAAGTTCAGCTTCTTAGGACTCTGCACTTCCCCAGAAGGAAGA
ATTAAAAATGAATATGTTCAAGGAAGCAGTGACCTTCAAGGACGTGGCTGTGGCCTTCACGGAGGAGGAATTGGGGCTGCTGGGCCCTGC
CCAGAGGAAGCTGTACCGAGATGTGATGGTGGAGAACTTTAGGAACCTGCTGTCAGTGGGGCATCCACCCTTCAAACAAGATGTATCACC
TATAGAAAGAAATGAGCAGCTTTGGATAATGACGACAGCAACCCGAAGACAGGGAAATTTAGGCATTGATGTTGAACAAGTGTCTGTCGT
CATCAACTTTGATCTTCCCGTGGACAAGGACGGGAATCCTGACAATGAGACCTACCTGCACCGGATCGGGCGCACGGGCCGCTTTGGCAA
GAGGGGCCTGGCAGTGAACATGGTGGACAGCAAGCACAGCATGAACATCCTGAACAGAATCCAGGAGCATTTTAATAAGAAGATAGAAAG
ATTGGACACAGATGATTTGGACGAGATTGAGAAAATAGCCAACTGAGAAGCTCCACCAGCCACTGATGCCAGCCCTGGCACTGCCCCTGC
ACAGGAGACAAGTGCGTTCAGGGCACAGGCCCCGACATCACCCCAAGGACAACGGCACAAGTAGAGAGAAACTACCTACCTCACTTCAAA
TTATGTTTGGACTTGACAAAAATGTATGCAAATGATGGGGGATGGTAGAAAAAAATTATTTACACAACCTTGGAAGATTAGGCATGAATA

>101648_101648_7_ZNF226-DDX19B_ZNF226_chr19_44677105_ENST00000590089_DDX19B_chr16_70366870_ENST00000563392_length(amino acids)=162AA_BP=78
MNMFKEAVTFKDVAVAFTEEELGLLGPAQRKLYRDVMVENFRNLLSVGHPPFKQDVSPIERNEQLWIMTTATRRQGNLGIDVEQVSVVIN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNF226-DDX19B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF226-DDX19B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF226-DDX19B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource