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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF236-RFX3 (FusionGDB2 ID:101679)

Fusion Gene Summary for ZNF236-RFX3

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF236-RFX3
Fusion gene ID: 101679
HgeneTgene
Gene symbol

ZNF236

RFX3

Gene ID

7776

5991

Gene namezinc finger protein 236regulatory factor X3
SynonymsZNF236A|ZNF236B-
Cytomap

18q23

9p24.2

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 236regulated by glucosetranscription factor RFX3DNA binding protein RFX3regulatory factor X, 3 (influences HLA class II expression)
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000253159, ENST00000320610, 
ENST00000583095, 		ENST00000302303, 
ENST00000358730, ENST00000381984, 
ENST00000382004, 
Fusion gene scores* DoF score6 X 6 X 4=14410 X 10 X 4=400
# samples 69
** MAII scorelog2(6/144*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/400*10)=-2.15200309344505
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF236 [Title/Abstract] AND RFX3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF236(74659608)-RFX3(3228889), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRFX3

GO:0045892

negative regulation of transcription, DNA-templated

12411430

TgeneRFX3

GO:0045893

positive regulation of transcription, DNA-templated

20148032


check buttonFusion gene breakpoints across ZNF236 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RFX3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A04U-01AZNF236chr18

74659608

+RFX3chr9

3228889

-


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Fusion Gene ORF analysis for ZNF236-RFX3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000253159ENST00000302303ZNF236chr18

74659608

+RFX3chr9

3228889

-
5CDS-intronENST00000253159ENST00000358730ZNF236chr18

74659608

+RFX3chr9

3228889

-
5CDS-intronENST00000253159ENST00000381984ZNF236chr18

74659608

+RFX3chr9

3228889

-
5CDS-intronENST00000320610ENST00000302303ZNF236chr18

74659608

+RFX3chr9

3228889

-
5CDS-intronENST00000320610ENST00000358730ZNF236chr18

74659608

+RFX3chr9

3228889

-
5CDS-intronENST00000320610ENST00000381984ZNF236chr18

74659608

+RFX3chr9

3228889

-
In-frameENST00000253159ENST00000382004ZNF236chr18

74659608

+RFX3chr9

3228889

-
In-frameENST00000320610ENST00000382004ZNF236chr18

74659608

+RFX3chr9

3228889

-
intron-3CDSENST00000583095ENST00000382004ZNF236chr18

74659608

+RFX3chr9

3228889

-
intron-intronENST00000583095ENST00000302303ZNF236chr18

74659608

+RFX3chr9

3228889

-
intron-intronENST00000583095ENST00000358730ZNF236chr18

74659608

+RFX3chr9

3228889

-
intron-intronENST00000583095ENST00000381984ZNF236chr18

74659608

+RFX3chr9

3228889

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000320610ZNF236chr1874659608+ENST00000382004RFX3chr93228889-119424915151961731
ENST00000253159ZNF236chr1874659608+ENST00000382004RFX3chr93228889-12133510619853871729

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000320610ENST00000382004ZNF236chr1874659608+RFX3chr93228889-0.0001364450.9998635
ENST00000253159ENST00000382004ZNF236chr1874659608+RFX3chr93228889-0.0001747180.9998253

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Fusion Genomic Features for ZNF236-RFX3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZNF236-RFX3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:74659608/chr9:3228889)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+27311023_104516361846.0Zinc fingerC2H2-type 20
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+27311051_107316361846.0Zinc fingerC2H2-type 21
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+27311167_118916361846.0Zinc fingerC2H2-type 22
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+27311195_121716361846.0Zinc fingerC2H2-type 23
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731121_14316361846.0Zinc fingerC2H2-type 4
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+27311223_124516361846.0Zinc fingerC2H2-type 24
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+27311251_127316361846.0Zinc fingerC2H2-type 25
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731153_17516361846.0Zinc fingerC2H2-type 5
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731197_21916361846.0Zinc fingerC2H2-type 6
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731225_24716361846.0Zinc fingerC2H2-type 7
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731253_27616361846.0Zinc fingerC2H2-type 8
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731285_30816361846.0Zinc fingerC2H2-type 9
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+273137_5916361846.0Zinc fingerC2H2-type 1
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731482_50416361846.0Zinc fingerC2H2-type 10
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731510_53216361846.0Zinc fingerC2H2-type 11
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731538_56016361846.0Zinc fingerC2H2-type 12
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731566_58816361846.0Zinc fingerC2H2-type 13
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731657_67916361846.0Zinc fingerC2H2-type 14
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+273166_8816361846.0Zinc fingerC2H2-type 2
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731685_70716361846.0Zinc fingerC2H2-type 15
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731713_73516361846.0Zinc fingerC2H2-type 16
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731741_76316361846.0Zinc fingerC2H2-type 17
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+273193_11516361846.0Zinc fingerC2H2-type 3
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731967_98916361846.0Zinc fingerC2H2-type 18
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+2731995_101716361846.0Zinc fingerC2H2-type 19
TgeneRFX3chr18:74659608chr9:3228889ENST00000302303016183_2580708.0DNA bindingRFX-type winged-helix
TgeneRFX3chr18:74659608chr9:3228889ENST00000358730014183_2580708.0DNA bindingRFX-type winged-helix

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+27311657_168016361846.0Zinc fingerC2H2-type 26
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+27311686_170816361846.0Zinc fingerC2H2-type 27
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+27311722_174416361846.0Zinc fingerC2H2-type 28
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+27311750_177216361846.0Zinc fingerC2H2-type 29
HgeneZNF236chr18:74659608chr9:3228889ENST00000253159+27311778_180116361846.0Zinc fingerC2H2-type 30
TgeneRFX3chr18:74659608chr9:3228889ENST000003820041518183_258656750.0DNA bindingRFX-type winged-helix


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Fusion Gene Sequence for ZNF236-RFX3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>101679_101679_1_ZNF236-RFX3_ZNF236_chr18_74659608_ENST00000253159_RFX3_chr9_3228889_ENST00000382004_length(transcript)=12133nt_BP=5106nt
GCCTGGAAACTACAAAGGATTGTGTTAATTTTGTGTTTAGGAAGAAAGAGGTAATGGGTAGGAATCAATGTAAACTTATTCATAGGCCAC
ACCAAACCAGGAATTCTTGTCGTGATTGCACTTGGTAGAGTTAACACACGTGCACATTACGGAAACGTTGGTGACCAACAGGCGTTTCAG
CGAGCTTTCGCACACCTCATGGGCCTTTGTGGGCTGCTGGAGAGATGTTGGCTGCACCATGACCCAGATGGAGTTTTAACATTGAATGCG
GAGAACACTAATTATGCCTATCAAGTTCCAAACTTCCATAAATGTGAAATCTGTCTACTATCTTTTCCAAAAGAATCCCAGTTTCAACGC
CACATGAGGGATCACGAGCGAAATGACAAGCCACATCGATGTGACCAGTGCCCCCAAACATTTAATGTTGAATTCAACCTGACACTTCAT
AAATGCACCCACAGCGGGGAAGATCCTACCTGCCCTGTGTGTAACAAGAAATTCTCCAGAGTGGCTAGTCTCAAAGCGCATATTATGCTA
CATGAAAAGGAAGAGAATCTCATCTGTTCTGAGTGTGGGGATGAGTTTACTCTGCAGAGTCAGCTGGCCGTGCACATGGAGGAGCACCGC
CAGGAGCTGGCTGGAACCCGGCAGCATGCCTGCAAGGCCTGCAAGAAAGAGTTCGAGACCTCCTCGGAGCTGAAGGAACACATGAAGACT
CATTACAAAATTAGGGTATCAAGTACAAGGTCTTATAACCGGAATATCGACAGAAGTGGATTCACGTATTCGTGTCCGCACTGTGGAAAG
ACGTTTCAAAAGCCAAGCCAGTTAACGCGACACATTAGGATACACACAGGTGAAAGGCCGTTCAAATGTAGTGAATGTGGAAAGGCTTTT
AACCAGAAGGGGGCACTGCAGACCCACATGATCAAGCACACAGGTGAAAAACCCCATGCCTGTGCCTTCTGTCCTGCCGCCTTCTCTCAG
AAAGGGAATCTTCAGTCGCACGTGCAGCGAGTCCACTCAGAGGTCAAGAATGGTCCTACCTATAACTGTACAGAATGTAGTTGTGTATTT
AAAAGTTTAGGCAGCTTAAACACGCATATCAGCAAGATGCATATGGGTGGGCCACAGAATTCAACAAGTTCTACAGAGACTGCTCATGTT
TTAACGGCCACACTTTTTCAGACGTTACCTCTTCAACAGACGGAAGCCCAAGCCACGTCGGCCTCAAGCCAGCCGAGCTCCCAGGCGGTG
AGCGACGTCATCCAGCAGCTCCTGGAGCTCTCAGAGCCGGCGCCGGTGGAGTCGGGGCAGTCCCCGCAGCCTGGGCAGCAGCTGAGCATC
ACAGTGGGCATCAACCAGGACATTTTACAGCAAGCCTTAGAAAACAGTGGGCTGTCTTCAATTCCAGCTGCAGCACATCCTAATGACTCC
TGCCATGCCAAGACCTCTGCACCACACGCTCAAAACCCAGATGTTTCCAGCGTTTCAAATGAGCAGACGGACCCCACAGACGCAGAGCAA
GAAAAAGAACAGGAAAGCCCGGAGAAACTGGATAAAAAAGAAAAAAAAATGATAAAGAAGAAGTCACCGTTTCTACCTGGCTCCATCCGC
GAGGAGAACGGCGTGCGCTGGCATGTGTGTCCCTACTGCGCCAAGGAGTTCCGCAAGCCCAGCGACCTGGTCCGCCACATCCGCATCCAC
ACCCACGAGAAGCCCTTCAAGTGCCCGCAGTGCTTCCGCGCCTTCGCCGTGAAGAGCACGCTGACAGCGCACATCAAGACGCACACCGGC
ATCAAGGCGTTCAAGTGCCAGTACTGCATGAAGAGCTTCTCCACCTCTGGCAGCCTCAAGGTGCACATTCGCCTGCACACAGGAGTTAGA
CCTTTTGCTTGTCCTCACTGTGACAAAAAATTTCGAACCTCAGGCCATAGGAAGACTCACATTGCTTCCCACTTTAAACATACGGAATTA
AGGAAAATGAGGCACCAGCGTAAACCTGCAAAGGTCCGTGTTGGCAAGACGAATATTCCAGTCCCTGATATTCCTTTGCAGGAACCAATC
CTCATAACTGACTTAGGTCTCATCCAGCCCATTCCAAAAAACCAGTTTTTCCAAAGCTATTTCAATAATAATTTTGTCAATGAAGCAGAT
AGACCATACAAGTGTTTTTACTGTCATCGTGCATATAAAAAATCTTGCCACCTTAAACAACACATCAGATCCCATACAGGTGAAAAACCT
TTTAAATGTTCTCAGTGTGGAAGAGGCTTTGTTTCTGCAGGCGTGCTCAAAGCACACATCAGAACACACACAGGACTGAAATCTTTCAAG
TGTCTGATATGTAATGGGGCTTTCACTACTGGTGGCAGCTTACGGCGACACATGGGTATCCACAACGACCTTCGTCCCTATATGTGTCCC
TATTGCCAAAAAACATTTAAGACTTCACTAAATTGCAAAAAGCACATGAAAACCCACAGATATGAGCTTGCCCAGCAGCTCCAACAGCAT
CAGCAGGCAGCCTCGATAGATGACAGCACTGTAGACCAGCAGAGCATGCAGGCCTCCACTCAAATGCAGGTGGAGATCGAGAGCGACGAG
CTGCCGCAGACGGCAGAGGTGGTCGCAGCGAACCCCGAGGCCATGCTGGACCTGGAGCCTCAGCATGTGGTGGGCACGGAGGAAGCAGGG
CTGGGCCAGCAGTTGGCAGATCAGCCCCTGGAAGCAGATGAAGATGGGTTTGTGGCTCCACAGGACCCTCTGCGAGGGCACGTAGACCAG
TTTGAAGAGCAGAGCCCTGCGCAACAGTCCTTCGAACCAGCAGGGCTACCCCAAGGTTTTACAGTGACTGATACGTACCATCAGCAGCCT
CAGTTTCCACCTGTCCAACAGCTACAGGATTCCAGCACACTTGAGTCTCAGGCCCTCTCCACAAGCTTCCACCAGCAGAGCTTGCTGCAG
GCTCCCAGCTCTGATGGGATGAATGTAACAACTCGCTTGATTCAGGAGTCATCCCAAGAGGAACTGGACCTGCAGGCACAAGGTTCCCAG
TTTCTGGAGGACAACGAGGACCAGAGCAGGCGCTCTTACAGGTGTGACTATTGCAACAAAGGCTTTAAGAAGTCCAGCCACCTGAAGCAG
CATGTGCGGTCGCACACCGGGGAAAAGCCCTACAAGTGCAAGCTCTGTGGACGCGGCTTTGTTTCCTCTGGGGTCCTCAAGTCCCACGAG
AAGACACACACAGGAGTGAAGGCGTTCAGCTGCAGTGTGTGCAATGCTTCCTTCACCACCAATGGCAGCCTCACCCGGCACATGGCCACA
CATATGAGCATGAAGCCTTATAAGTGTCCGTTTTGTGAGGAGGGTTTCCGAACTACAGTGCATTGTAAAAAGCACATGAAGAGACACCAA
ACAGTCCCCTCTGCTGTGTCAGCCACTGGAGAGACAGAAGGAGGAGACATTTGTATGGAGGAAGAGGAAGAACATTCTGACAGAAATGCA
TCACGGAAGTCTCGTCCTGAGGTCATCACTTTCACGGAGGAGGAGACAGCCCAGTTAGCCAAGATCCGGCCGCAGGAGAGCGCCACGGTG
TCAGAGAAGGTCCTGGTGCAGTCCGCGGCAGAAAAGGACCGCATCAGTGAGCTGAGGGACAAGCAGGCGGAGCTGCAGGACGAGCCCAAG
CACGCCAACTGCTGCACATACTGCCCCAAGAGCTTCAAGAAACCTAGCGACCTGGTGAGGCATGTTCGAATCCATACTGGAGAAAAGCCA
TACAAATGTGATGAATGTGGAAAGAGTTTTACTGTGAAATCCACTCTCGATTGTCATGTGAAGACTCACACAGGTCAGAAGCTCTTCAGC
TGTCACGTCTGCAGCAACGCCTTCTCCACGAAGGGAAGTCTGAAGGTCCACATGCGCCTGCACACGGGAGCCAAGCCCTTCAAATGCCCG
CATTGCGAGCTGCGTTTCCGTACCTCGGGTAGAAGAAAGACACACATGCAGTTTCATTATAAACCAGACCCAAAGAAGGCCAGAAAGCCT
ATGACTCGAAGCTCATCGGAAGGACTGCAGCCTGTAAACCTCCTCAACTCCTCCTCTACTGACCCAAACGTGTTTATCATGAACAACTCT
GTTCTAACAGGACAGTTTGATCAGAATCTGCTGCAACCAGGACTGGTGGGCCAAGCTATTCTCCCTGCCTCTGTGTCAGCTGGGGGTGAC
CTGACCGTGTCTCTGACAGATGGGAGCCTGGCTACCCTAGAAGGCATCCAGTTACAGTTGGCTGCTAACTTGGTTGGACCAAATGTACAG
ATTTCTGGAATCGATGCTGCCAGCATTAATAACATTACGTTGCAGATTGATCCAAGCATTCTGCAGCAGACGCTACAGCAGGGCAACCTA
TTGGCTCAGCAGCTCACGGGGGAGCCTGGCCTGGCCCCACAGAACAGCTCTCTCCAGACATCGGACAGCACGGTCCCTGCCAGTGTTGTC
ATCCAGCCCATCTCAGGCCTGTCCTTACAGCCCACAGTGACCTCTGCGAACCTGACCATAGGCCCGCTGTCTGAGCAGGATTCAGTGCTG
ACCACTAACAGCAGTGGGACCCAAGACCTCACTCAAGTGATGACTTCGCAAGGTCTAGTGTCCCCCTCCGGCGGTCCCCACGAGATCACC
CTGACCATTAACAACTCCAGCCTGAGCCAGGTCCTGGCACAGGCCGCTGGGCCCACTGCCACGTCTTCCTCGGGGTCTCCACAGGAAATT
ACCCTGACTATCTCCGAACTTAACACTACAAGCGGAAGCCTTCCTTCAACAACACCGATGTCTCCATCGGCCATCTCGACTCAGAACCTG
GTCATGTCCTCGTCGGGCGTGGGAGGTGACGCTAGTGTCACGCTGACGCTGGCCGATACTCAGGGTATGCTATCTGGAGGCCTGGACACT
GTCACACTCAACATCACCTCTCAGGGTCAGCAGTTCCCAGCGCTCCTCACGGATCCCTCTCTCTCGGGCCAGGGTGGAGCAGGCTCGCCG
CAAGTCATACTAGTGAGCCACACGCCACAGTCAGCGTCTGCTGCTTGTGAAGAAATAGCCTACCAGTTTGGTGATTTAAATGCCGTGTCT
CCTGGAAATCTGGATAAAGATGAAGGCAGTGAAGTAGAAAGTGAAATGGATGAAGAACTGGATGACTCTTCAGAGCCTCAAGCCAAAAGA
GAGAAAACAGAGCTGAGCCAGGCATTTCCAGTGGGCTGCATGCAGCCTGTTCTCGAGACTGGCGTGCAACCAAGCCTCCTGAATCCAATT
CACAGCGAGCACATTGTCACAAGTACTCAGACTATCAGACAGTGCAGCGCTACAGGAAATACCTACACTGCAGTCTAAAGAATATTAAAG
CGTATTTTTCCAGCTTACATTAACCCTGTTGATATTGGGCTTAAGTTGAAAATTTAATAAGCCTGAAGGTCGACTGTTGTCAAATTCTAT
CTGTGCTGAACATTAACTTTTTGGAGTTGTGAAATGGAATGGGTGTATGTATTTTGCCAGATCTTTTTTTTTAACGTAAACAAATTATTT
GCTTCTTAATAATGAATTTTTTCCCTTAGTTTCAGGTGTCAAGAAGGATTTTTACAACACTTAATGTCAATGTTTTGTTTTCTTATAATT
AAAAAGTAATTTACATTTTTTGTAGCTTAAAATATTTTATTGTTGATTGTTAGTCTTGGTGTATGATTTCATGTGTAAGTTTTTTAATTA
GATGCACTTCTGTGAAATATCAAAAGAAATGATTTTTTTGATTTACACTGGAGGCATGCCCATTTGGCAGCAGATGCATCAAATTTGCTT
TTGAAAGGTGCTTTTCATTGGACAGAACCATAAGACACTATTTTGATAACATTTTGAGTATGGAGAGAGAATACAGAGCATTTTTATTAT
AGTGCTAGAGGGTTTGGAAGGTCATCTATTTTTCTCTGAGGAAAAAATGAGCTGTACATTTATCAGTTCAGAGTAAATGACAGAATTGCA
AGAGATTATGCTAATATGTACATAATTTGTGTACATAATTATTAAACCATGTTAACAATGCAAGCTTCCGTTAAACATTGAATTTTAACT
ATTATTTGCATACCAATTCCTCTGTTTAAAGACTACTGATTCTGTATTTGGGACCACTGCACAGATGCATTCTGCTGTTAAGTGGGGGCT
GTTATAGTTAGATACTGAAGCAGAAAAAAAAGACTTGACTTTTTTTTTTTAAGTGTACATGCTACTTATGCTGAGCTGGACATACAGGAA
ACCATTCCATTTGGATGACTTTCTTTTATTCCAGGTCTTTTTCCTAATAGTAGTTCAATATGCTGCTATTATAAACGAGAATTTATAGAA
TGCAAGGAATGTAGCAACCTACATAACGTTATTTCCTTCAAAACTATTTCCTGGTTTCTAAAGTATGTGGATTTAAATTGTAAACAGAAC
CTGAAGGCAGTGTAACTGGCACACCTCACTGTTACTTATCCCCAATTCTGTAGGATTTGGATAGGTGGCTGGATGGACCATTGCCATTGA
AGAATGTACATCAGGGATCATCGTACCTCGGCTATTACATGGTGCCTTAAAACAGAACTGAAGCTAAGGTTTAGTAAGGTTTATTTTGTT
CATGTGACTAACTCTTCAATCCATTTGACAAAGTGTGCCTGTCATTTTCAGATTCCTGAAGTAAGGACAGGTGACATGTTCTTCAAAGGA
AATTTAGGGAAAACAAAGGAAAACAAAAAGACAAAAATCAGTTTCCCTCTTTGAGTGACCGTGGATCTATTTTTTATTCTTAGAGCTGAA
TATTACTTGATTACAAATCAGATTGCTTAAGGGTGTGGAATAGCAGGCTAGTTTTAATACCAACTTGTTAACATAAAATCATATATGTTT
TAGACCATTCTTATTTAGTTACAATTTTAGAAAGTTAACAAAGTAAGCAGGTACTTATCGAAGTGCATCTTTTCAGTCTAAATGTTTGTC
TGTGTGTCTAGGTGCTGGTGAGTCCACATGGACACATGAGTGCCCATGGGGCAGGAGTCTGCTATAAAGTCAGAAGGTGAGATCCTAGAG
AGTTACACCCAGCCCCATTTTAATTTGCATGAAAAGCCAAGGTTCTTTTAAGCACTCAAATTATTTAATGATTAAAACACAAGAAAGGCA
CATCTGTTCATTTAAATAGTTGTAAAAAACTAATCAGCAAAAATAAATAGATAATAAAGCCAAAAAAAAGGAAAGCACAAAATGATTGAC
AGATTATCAAATGAGGCCTATATTAAACCCAAGATGTTTATCTTTCCAGTGGTATTGGGGTAAGGGGGGTGGGGGGTTGGAAAGACGAGG
TGAGCCAGTCTGTAAAGTTAGAAATACCAAATGGCTTATCGGGTAATACACAGTGTATTTAAGCTGTTGTTGCTTAATTGCCTCAGACTA
CTCAAATAACATCAACAACATTTCTTAAGTAAAATTTAAATATTTTAGATGTAATTTTAAAAACTGATCCAAATTTTTTATTATACAACT
CACTCATATATTTGAAAGTCTTCACTAGCATAGTAGCATCACCTTCATCTAAATGTCATTTAAATTACTGTCCCCCTTTTTCCTCCCAAA
AAGACAATGGATTTGTACCAAAACACACACAAAAAAGGCAAACAAAACATGATAATCTGCAAAAGTTCATGTATCTACTTCATTGTGCAT
AGGAAGTGTTTACAGGTAAAATTAAAATCAAAAATTGAAAAAACACTCTTCATTTTGGCTCTCCTTTCTGAATTTTTTCAGTTTCCTGTC
TCTACCCGCCATCCTTTGAGTGATACTATATCTGTATTGGACCAAATGTATTTACTGGTTTCATTTTGTTTATTGAATGACTTTAAATGT
ATTTATTATCATTGTTTAATTTAATGTTGGATATATTTGTATCATTACAGGAATCTGGTAATAATGGGCAAATTTAGATTGATGAGGCTT
AGGGATCGGGGATGCTCCAGGATTCAACATTTCTTCCAATTGTTCATGGTTTGTTCTAAATTAGGACAGATTAAGAACTAATAAAACATT
ATTACATTTGAACTTGACTCAATAAAAATATTCTGATCTCCTTTATGAATATTAGGAATATTCTTTGTGATTAGTGTAAGTAGTTTGGAT
CAAAACATAAAAAGAAGACCTATGGTTTATGCTACTTCTAGTTATTTGTAGTTCACAGTAAAACATGCACAGACATACACACAAACATTT
TCATCAATTTCGAATTTGAATTGTGAAAAATATATAAGAAAATAAAAACAATTTATACATTTGAGCAAATTGAGCAATCACATTTATTGC
ATTTATTTCCCTTTTTCCCTTTTTTCACTCATTGAAAGTGTGGGTTTTCTAAATAATATTAGACACTAACACTCAACAGATTTATTCACA
AATGACACAAGTACACATTTTAAGACTTCTTTGTATTTCTTGCAATTATAACCAATCACTAGTCATGAAATATACCTACATAAACCAAGT
CCTACACTTTCAGTGAGGAAGAATGTAAGGAAGGTATGTTGACTGTTTTCAAGTTTCAGAAAAGATATTTTCATATGATAGGATTGAGTA
TCATGGGTATAGTTTGATCTTGACATATAGTTTGAAAATCATACTCAAAAGATTTGCATTCATGAAACCAGTGAACAATAGGGTGGAATG
GATGAACCATCTCCTTGGAAGACAGGGCCCAATTTTCAATTTTTTCTTTGGCTATCAAGTTGCTAGTCACTTATTCAGGATTTTCATCCA
AACTGTGTTTGGACTGACTGTATAAGTCTTACTGCCTTTTCAGAAATCTGCTTTCCTTTGTGTGATTTTTCTTGTACTGTATAGCACGGT
TTATGCACCTCTCTTTAGATGGTGTACTTTAAAAACAAAAGTAAAATTTAGAAAATGGTTTTAACACTGCATACCTAAAATTAGTAGTGT
GCAGCATTGACTGCCTTTGATTTGTAGTAGACAAGTAAAAATGAATACGTTCTTGTAGAATGCTGTAAAAGTTATTCAGGAATGAATACG
GTTTTAGTGCCGTAATCATGAATCTTTTTATATGAATGCACTGTCTAAAAGTGCTAAATGCATTTTCAAATTTTTAAAAATTCCTCAGAT
GATATATTTGAAATGTCTAAAATAATGCTGTGCTTGAAACATTAGTGTAAAAGGAAAAAAAAAATAGTGTCACTGTGATGTTGGTCCTCC
CTGTGTGGACACAAGTAGAAAGAAAAAACTTGGCAAGTCACCTTTGTGTACAATTTGAGGCAGTGGTTATATACAATAAATTGACCTTTA
TTATATCCCCCAGACACACACATTCTTGGTGAGAAAAGAACAACCATCCAGAAATTGAGATGAGAACTTTTGTGATCTGTATGAATCACA
GCAGATCATGGGGGAGGAGGATTGGCATGCAGTGCTGTTGAAAATTGGGCTTGTTGTTAGATCAGAACAACCTCCATGTATATGGTTAGA
ACGAATCAATTAATGGAATCCTAGTATTTCTGCAAGTTTGGTGATTTTTAAAAACTGGAATAGAAGCATTAATTCAGTGCTTAGTTCTAG
TATTAGAAAACCCCTTTGATGTAATGCCTTGTATTAACCCTTTGAGCATTGTAAGATATACAATGGGGGACAAAAGCCTTTCAGATCATT
TATTTAGACTTAGACCGGTAAAGTATACTCTATATCCAAATGTCTAATTATGCTGTTTTTTTAAAGGGGGGGGTAGGAAGAGAAAGTGTT
TCCACGCCGAACACTTGCATTTTATATACAACTCTTAATTTTTCTTCAAGAGGGCTTGATATATTTATTCCCAAATATTCACTGCCATCT
AAGTAAGTGTACTGTTTACAGAAAAAAAAAATCAACTTTTCTAGTATCACACCATAGTCTCTAGAAAAGGAGGACAAATACATGGGCCTG
GATAGACCTATGTCATAACTGATTTCTGCACATTGAAGGTACCTAGATTGCCTTTAAAAGGTATAAAGAAAGGGTTAAGTTTCTTTTTTT
TTTGTCTTTTTTTTCCCAAAATGAATCAAAAGATCTCATTTATTTAGCTTTAGAAAGTACAAGTGTAAGTAAAGCCTTAGGAAGAAAGGA
GTTCGAGTGGATTAAGAGAATCTGAACTCTTTGGGGGCAGTTAGGCTATTTGGAGTTAGATCGCTCATAAAATATTGTTTGCGAATTTCA
CACAGGGCATAATTTTATCTATGCTCCAAAACTTTAATACGTTGTCAAAAAATTATATATAGATAGAATGGAGAGCAAAGCACTTGATTT
TAAGCTCATCTGTCAGGAGATGCTATGACTACTGCTTCTGATATCTCTAAATGTCAGTCTGCTTACACCATTGCTGATTTTGTTCAAGGG
AATCTCTTCGTGCACTTGATTCCCTCTGTTCCCTGCGTGATCGAACATGAAAGCAGTGTTGTCTGCAGATGTGCTTGCGCTGCCCTAGCT
GGGTGCAAATAAGAGTGTAACCTATTCTGATGTCTGGTGAAAGGACATCCATAGCATAGTGCAAGTATGCCGTAAACGTTGCTTTTTAGG
CAGTTTAGGAAGTCAGACCATGCAAATTACTCATGTGTTAACATGCAATACTCAAAGGGTTTTAATTTAACTCTCTTCTTTTGAATTCTT
CATGATGATTTACTGTAAATGCTTCTCAGTTTGCATGCCTTGATCATTGCTGCTAGTGATTTTATGTGCCAGTAGACCTGAGTTTAGTTT
ACCAATTTTACTTAAATAGTAAAAGCCACTTACAAAGTGACTGCCTAGGATTTTTTTTTCCTTTCATTTGAAATAATTGATAATATGTTT
TTTTAAAAAGAAAAATGTGTTTTGTCTCTTCTTTTATTTGGTTCTGGTTTGATTCTTTTTCTCCCCTCTTTCCTTTGTTTTTTTTTTTTA
AATAAATTATGATGTTGGGATTGGAAGCCCTGAGTAATGAAAATCTTTGGTAAGAATTGTTTATGTAGCTCAATAACGAGGACAACAAAT
ATTCTTTAGAAGAATTTTGATTCTGGGGAGGAAAGAAAATATAAAAACTCCCATTGACTGTTGATAACCAAGTAAATTTTTCCTTCAGTA
AATTAGTATTTTTGAAGAAACGATCGCCTTGTTTTAACTTGCTAAACAACAATTTTAAATGACCCAATAAAGAATCTATTGAACTTTATT
CGTTTAAAAAGCATCTTTTGTACCAAAGCAAATTTTTTTCTCTACTCATTTCCATCATCAATTTGGACCTATGGTGGTGACCAATGCATT
GGTTACAGAAACTTTAAGTGAGTGCCTTGAGAAAACTTGGAAATTTGTGCCTGAGGTGGTAAACTTTTAATTAGGTTAATTGTAGTGCTT
ACCAATCAGTAACTTCACTATCACTCAGGGCTTTCGTACCTTCTAGGTAAAACTTCTTTCATTGTGTTTTTTTAAGATACTGTATTTTTT
TTTAAGTGCCATCATTTAAATTTCACTTAGTAAGTGGCAGATTACATTATTCAGTCCCACAAGCACAGAAACATAGTAACACTAGGAGAT
ATTTGAACATTTATTTTACAATCGACTGAATATATTATGTAAATGAGGTAAGCAACTTTTGTAGAGATTGTATGTGTGAGATAATGTAAT
GTTCTTTTCCAGTTTTTGGACTACAGTTGAATAAACTTTTTAATTATTTAAAAACATCTTTACCGAATAACATGTGATGGTTTTTTGTAT
AATGTATTTGATTTTGTAAATACGTATTTCCTGATGTGATTTTTGTGAGAAATGCTAAATCTTTTAGTATATCATGTCCTCTCAAAATTG
GCAGGAGCTAAATAATAGTTTGTGGGCGATTTGTATTGTGTACTGTACAATAACTGGGGAACTTTTATAATTATAAAAATATATATTAAC
TTTTAGTGTGTTGTTTAAACAAATGACTGGAACATACTAAAGATATTAGTAGGATTTTTCTGAATATTTCAGACTTGAACTCAGGCTAGC

>101679_101679_1_ZNF236-RFX3_ZNF236_chr18_74659608_ENST00000253159_RFX3_chr9_3228889_ENST00000382004_length(amino acids)=1729AA_BP=981
MGLCGLLERCWLHHDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSG
EDPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRV
SSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQS
HVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQ
LLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQES
PEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKC
QYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLG
LIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNG
AFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAE
VVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQ
QLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHT
GEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAV
SATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANCCT
YCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRF
RTSGRRKTHMQFHYKPDPKKARKPMTRSSSEGLQPVNLLNSSSTDPNVFIMNNSVLTGQFDQNLLQPGLVGQAILPASVSAGGDLTVSLT
DGSLATLEGIQLQLAANLVGPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPGLAPQNSSLQTSDSTVPASVVIQPISG
LSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEITLTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISE
LNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGSPQVILVS
HTPQSASAACEEIAYQFGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEHIV

--------------------------------------------------------------
>101679_101679_2_ZNF236-RFX3_ZNF236_chr18_74659608_ENST00000320610_RFX3_chr9_3228889_ENST00000382004_length(transcript)=11942nt_BP=4915nt
GATGCCGCGGGGCCGCCCCCCGAAGCCCAGGGAGAGCAAGGCGCGCGGCGACTCCGATGGAGTTTTAACATTGAATGCGGAGAACACTAA
TTATGCCTATCAAGTTCCAAACTTCCATAAATGTGAAATCTGTCTACTATCTTTTCCAAAAGAATCCCAGTTTCAACGCCACATGAGGGA
TCACGAGCGAAATGACAAGCCACATCGATGTGACCAGTGCCCCCAAACATTTAATGTTGAATTCAACCTGACACTTCATAAATGCACCCA
CAGCGGGGAAGATCCTACCTGCCCTGTGTGTAACAAGAAATTCTCCAGAGTGGCTAGTCTCAAAGCGCATATTATGCTACATGAAAAGGA
AGAGAATCTCATCTGTTCTGAGTGTGGGGATGAGTTTACTCTGCAGAGTCAGCTGGCCGTGCACATGGAGGAGCACCGCCAGGAGCTGGC
TGGAACCCGGCAGCATGCCTGCAAGGCCTGCAAGAAAGAGTTCGAGACCTCCTCGGAGCTGAAGGAACACATGAAGACTCATTACAAAAT
TAGGGTATCAAGTACAAGGTCTTATAACCGGAATATCGACAGAAGTGGATTCACGTATTCGTGTCCGCACTGTGGAAAGACGTTTCAAAA
GCCAAGCCAGTTAACGCGACACATTAGGATACACACAGGTGAAAGGCCGTTCAAATGTAGTGAATGTGGAAAGGCTTTTAACCAGAAGGG
GGCACTGCAGACCCACATGATCAAGCACACAGGTGAAAAACCCCATGCCTGTGCCTTCTGTCCTGCCGCCTTCTCTCAGAAAGGGAATCT
TCAGTCGCACGTGCAGCGAGTCCACTCAGAGGTCAAGAATGGTCCTACCTATAACTGTACAGAATGTAGTTGTGTATTTAAAAGTTTAGG
CAGCTTAAACACGCATATCAGCAAGATGCATATGGGTGGGCCACAGAATTCAACAAGTTCTACAGAGACTGCTCATGTTTTAACGGCCAC
ACTTTTTCAGACGTTACCTCTTCAACAGACGGAAGCCCAAGCCACGTCGGCCTCAAGCCAGCCGAGCTCCCAGGCGGTGAGCGACGTCAT
CCAGCAGCTCCTGGAGCTCTCAGAGCCGGCGCCGGTGGAGTCGGGGCAGTCCCCGCAGCCTGGGCAGCAGCTGAGCATCACAGTGGGCAT
CAACCAGGACATTTTACAGCAAGCCTTAGAAAACAGTGGGCTGTCTTCAATTCCAGCTGCAGCACATCCTAATGACTCCTGCCATGCCAA
GACCTCTGCACCACACGCTCAAAACCCAGATGTTTCCAGCGTTTCAAATGAGCAGACGGACCCCACAGACGCAGAGCAAGAAAAAGAACA
GGAAAGCCCGGAGAAACTGGATAAAAAAGAAAAAAAAATGATAAAGAAGAAGTCACCGTTTCTACCTGGCTCCATCCGCGAGGAGAACGG
CGTGCGCTGGCATGTGTGTCCCTACTGCGCCAAGGAGTTCCGCAAGCCCAGCGACCTGGTCCGCCACATCCGCATCCACACCCACGAGAA
GCCCTTCAAGTGCCCGCAGTGCTTCCGCGCCTTCGCCGTGAAGAGCACGCTGACAGCGCACATCAAGACGCACACCGGCATCAAGGCGTT
CAAGTGCCAGTACTGCATGAAGAGCTTCTCCACCTCTGGCAGCCTCAAGGTGCACATTCGCCTGCACACAGGAGTTAGACCTTTTGCTTG
TCCTCACTGTGACAAAAAATTTCGAACCTCAGGCCATAGGAAGACTCACATTGCTTCCCACTTTAAACATACGGAATTAAGGAAAATGAG
GCACCAGCGTAAACCTGCAAAGGTCCGTGTTGGCAAGACGAATATTCCAGTCCCTGATATTCCTTTGCAGGAACCAATCCTCATAACTGA
CTTAGGTCTCATCCAGCCCATTCCAAAAAACCAGTTTTTCCAAAGCTATTTCAATAATAATTTTGTCAATGAAGCAGATAGACCATACAA
GTGTTTTTACTGTCATCGTGCATATAAAAAATCTTGCCACCTTAAACAACACATCAGATCCCATACAGGTGAAAAACCTTTTAAATGTTC
TCAGTGTGGAAGAGGCTTTGTTTCTGCAGGCGTGCTCAAAGCACACATCAGAACACACACAGGACTGAAATCTTTCAAGTGTCTGATATG
TAATGGGGCTTTCACTACTGGTGGCAGCTTACGGCGACACATGGGTATCCACAACGACCTTCGTCCCTATATGTGTCCCTATTGCCAAAA
AACATTTAAGACTTCACTAAATTGCAAAAAGCACATGAAAACCCACAGATATGAGCTTGCCCAGCAGCTCCAACAGCATCAGCAGGCAGC
CTCGATAGATGACAGCACTGTAGACCAGCAGAGCATGCAGGCCTCCACTCAAATGCAGGTGGAGATCGAGAGCGACGAGCTGCCGCAGAC
GGCAGAGGTGGTCGCAGCGAACCCCGAGGCCATGCTGGACCTGGAGCCTCAGCATGTGGTGGGCACGGAGGAAGCAGGGCTGGGCCAGCA
GTTGGCAGATCAGCCCCTGGAAGCAGATGAAGATGGGTTTGTGGCTCCACAGGACCCTCTGCGAGGGCACGTAGACCAGTTTGAAGAGCA
GAGCCCTGCGCAACAGTCCTTCGAACCAGCAGGGCTACCCCAAGGTTTTACAGTGACTGATACGTACCATCAGCAGCCTCAGTTTCCACC
TGTCCAACAGCTACAGGATTCCAGCACACTTGAGTCTCAGGCCCTCTCCACAAGCTTCCACCAGCAGAGCTTGCTGCAGGCTCCCAGCTC
TGATGGGATGAATGTAACAACTCGCTTGATTCAGGAGTCATCCCAAGAGGAACTGGACCTGCAGGCACAAGGTTCCCAGTTTCTGGAGGA
CAACGAGGACCAGAGCAGGCGCTCTTACAGGTGTGACTATTGCAACAAAGGCTTTAAGAAGTCCAGCCACCTGAAGCAGCATGTGCGGTC
GCACACCGGGGAAAAGCCCTACAAGTGCAAGCTCTGTGGACGCGGCTTTGTTTCCTCTGGGGTCCTCAAGTCCCACGAGAAGACACACAC
AGGAGTGAAGGCGTTCAGCTGCAGTGTGTGCAATGCTTCCTTCACCACCAATGGCAGCCTCACCCGGCACATGGCCACACATATGAGCAT
GAAGCCTTATAAGTGTCCGTTTTGTGAGGAGGGTTTCCGAACTACAGTGCATTGTAAAAAGCACATGAAGAGACACCAAACAGTCCCCTC
TGCTGTGTCAGCCACTGGAGAGACAGAAGGAGGAGACATTTGTATGGAGGAAGAGGAAGAACATTCTGACAGAAATGCATCACGGAAGTC
TCGTCCTGAGGTCATCACTTTCACGGAGGAGGAGACAGCCCAGTTAGCCAAGATCCGGCCGCAGGAGAGCGCCACGGTGTCAGAGAAGGT
CCTGGTGCAGTCCGCGGCAGAAAAGGACCGCATCAGTGAGCTGAGGGACAAGCAGGCGGAGCTGCAGGACGAGCCCAAGCACGCCAACTG
CTGCACATACTGCCCCAAGAGCTTCAAGAAACCTAGCGACCTGGTGAGGCATGTTCGAATCCATACTGGAGAAAAGCCATACAAATGTGA
TGAATGTGGAAAGAGTTTTACTGTGAAATCCACTCTCGATTGTCATGTGAAGACTCACACAGGTCAGAAGCTCTTCAGCTGTCACGTCTG
CAGCAACGCCTTCTCCACGAAGGGAAGTCTGAAGGTCCACATGCGCCTGCACACGGGAGCCAAGCCCTTCAAATGCCCGCATTGCGAGCT
GCGTTTCCGTACCTCGGGTAGAAGAAAGACACACATGCAGTTTCATTATAAACCAGACCCAAAGAAGGCCAGAAAGCCTATGACTCGAAG
CTCATCGGAAGGACTGCAGCCTGTAAACCTCCTCAACTCCTCCTCTACTGACCCAAACGTGTTTATCATGAACAACTCTGTTCTAACAGG
ACAGTTTGATCAGAATCTGCTGCAACCAGGACTGGTGGGCCAAGCTATTCTCCCTGCCTCTGTGTCAGCTGGGGGTGACCTGACCGTGTC
TCTGACAGATGGGAGCCTGGCTACCCTAGAAGGCATCCAGTTACAGTTGGCTGCTAACTTGGTTGGACCAAATGTACAGATTTCTGGAAT
CGATGCTGCCAGCATTAATAACATTACGTTGCAGATTGATCCAAGCATTCTGCAGCAGACGCTACAGCAGGGCAACCTATTGGCTCAGCA
GCTCACGGGGGAGCCTGGCCTGGCCCCACAGAACAGCTCTCTCCAGACATCGGACAGCACGGTCCCTGCCAGTGTTGTCATCCAGCCCAT
CTCAGGCCTGTCCTTACAGCCCACAGTGACCTCTGCGAACCTGACCATAGGCCCGCTGTCTGAGCAGGATTCAGTGCTGACCACTAACAG
CAGTGGGACCCAAGACCTCACTCAAGTGATGACTTCGCAAGGTCTAGTGTCCCCCTCCGGCGGTCCCCACGAGATCACCCTGACCATTAA
CAACTCCAGCCTGAGCCAGGTCCTGGCACAGGCCGCTGGGCCCACTGCCACGTCTTCCTCGGGGTCTCCACAGGAAATTACCCTGACTAT
CTCCGAACTTAACACTACAAGCGGAAGCCTTCCTTCAACAACACCGATGTCTCCATCGGCCATCTCGACTCAGAACCTGGTCATGTCCTC
GTCGGGCGTGGGAGGTGACGCTAGTGTCACGCTGACGCTGGCCGATACTCAGGGTATGCTATCTGGAGGCCTGGACACTGTCACACTCAA
CATCACCTCTCAGGGTCAGCAGTTCCCAGCGCTCCTCACGGATCCCTCTCTCTCGGGCCAGGGTGGAGCAGGCTCGCCGCAAGTCATACT
AGTGAGCCACACGCCACAGTCAGCGTCTGCTGCTTGTGAAGAAATAGCCTACCAGTTTGGTGATTTAAATGCCGTGTCTCCTGGAAATCT
GGATAAAGATGAAGGCAGTGAAGTAGAAAGTGAAATGGATGAAGAACTGGATGACTCTTCAGAGCCTCAAGCCAAAAGAGAGAAAACAGA
GCTGAGCCAGGCATTTCCAGTGGGCTGCATGCAGCCTGTTCTCGAGACTGGCGTGCAACCAAGCCTCCTGAATCCAATTCACAGCGAGCA
CATTGTCACAAGTACTCAGACTATCAGACAGTGCAGCGCTACAGGAAATACCTACACTGCAGTCTAAAGAATATTAAAGCGTATTTTTCC
AGCTTACATTAACCCTGTTGATATTGGGCTTAAGTTGAAAATTTAATAAGCCTGAAGGTCGACTGTTGTCAAATTCTATCTGTGCTGAAC
ATTAACTTTTTGGAGTTGTGAAATGGAATGGGTGTATGTATTTTGCCAGATCTTTTTTTTTAACGTAAACAAATTATTTGCTTCTTAATA
ATGAATTTTTTCCCTTAGTTTCAGGTGTCAAGAAGGATTTTTACAACACTTAATGTCAATGTTTTGTTTTCTTATAATTAAAAAGTAATT
TACATTTTTTGTAGCTTAAAATATTTTATTGTTGATTGTTAGTCTTGGTGTATGATTTCATGTGTAAGTTTTTTAATTAGATGCACTTCT
GTGAAATATCAAAAGAAATGATTTTTTTGATTTACACTGGAGGCATGCCCATTTGGCAGCAGATGCATCAAATTTGCTTTTGAAAGGTGC
TTTTCATTGGACAGAACCATAAGACACTATTTTGATAACATTTTGAGTATGGAGAGAGAATACAGAGCATTTTTATTATAGTGCTAGAGG
GTTTGGAAGGTCATCTATTTTTCTCTGAGGAAAAAATGAGCTGTACATTTATCAGTTCAGAGTAAATGACAGAATTGCAAGAGATTATGC
TAATATGTACATAATTTGTGTACATAATTATTAAACCATGTTAACAATGCAAGCTTCCGTTAAACATTGAATTTTAACTATTATTTGCAT
ACCAATTCCTCTGTTTAAAGACTACTGATTCTGTATTTGGGACCACTGCACAGATGCATTCTGCTGTTAAGTGGGGGCTGTTATAGTTAG
ATACTGAAGCAGAAAAAAAAGACTTGACTTTTTTTTTTTAAGTGTACATGCTACTTATGCTGAGCTGGACATACAGGAAACCATTCCATT
TGGATGACTTTCTTTTATTCCAGGTCTTTTTCCTAATAGTAGTTCAATATGCTGCTATTATAAACGAGAATTTATAGAATGCAAGGAATG
TAGCAACCTACATAACGTTATTTCCTTCAAAACTATTTCCTGGTTTCTAAAGTATGTGGATTTAAATTGTAAACAGAACCTGAAGGCAGT
GTAACTGGCACACCTCACTGTTACTTATCCCCAATTCTGTAGGATTTGGATAGGTGGCTGGATGGACCATTGCCATTGAAGAATGTACAT
CAGGGATCATCGTACCTCGGCTATTACATGGTGCCTTAAAACAGAACTGAAGCTAAGGTTTAGTAAGGTTTATTTTGTTCATGTGACTAA
CTCTTCAATCCATTTGACAAAGTGTGCCTGTCATTTTCAGATTCCTGAAGTAAGGACAGGTGACATGTTCTTCAAAGGAAATTTAGGGAA
AACAAAGGAAAACAAAAAGACAAAAATCAGTTTCCCTCTTTGAGTGACCGTGGATCTATTTTTTATTCTTAGAGCTGAATATTACTTGAT
TACAAATCAGATTGCTTAAGGGTGTGGAATAGCAGGCTAGTTTTAATACCAACTTGTTAACATAAAATCATATATGTTTTAGACCATTCT
TATTTAGTTACAATTTTAGAAAGTTAACAAAGTAAGCAGGTACTTATCGAAGTGCATCTTTTCAGTCTAAATGTTTGTCTGTGTGTCTAG
GTGCTGGTGAGTCCACATGGACACATGAGTGCCCATGGGGCAGGAGTCTGCTATAAAGTCAGAAGGTGAGATCCTAGAGAGTTACACCCA
GCCCCATTTTAATTTGCATGAAAAGCCAAGGTTCTTTTAAGCACTCAAATTATTTAATGATTAAAACACAAGAAAGGCACATCTGTTCAT
TTAAATAGTTGTAAAAAACTAATCAGCAAAAATAAATAGATAATAAAGCCAAAAAAAAGGAAAGCACAAAATGATTGACAGATTATCAAA
TGAGGCCTATATTAAACCCAAGATGTTTATCTTTCCAGTGGTATTGGGGTAAGGGGGGTGGGGGGTTGGAAAGACGAGGTGAGCCAGTCT
GTAAAGTTAGAAATACCAAATGGCTTATCGGGTAATACACAGTGTATTTAAGCTGTTGTTGCTTAATTGCCTCAGACTACTCAAATAACA
TCAACAACATTTCTTAAGTAAAATTTAAATATTTTAGATGTAATTTTAAAAACTGATCCAAATTTTTTATTATACAACTCACTCATATAT
TTGAAAGTCTTCACTAGCATAGTAGCATCACCTTCATCTAAATGTCATTTAAATTACTGTCCCCCTTTTTCCTCCCAAAAAGACAATGGA
TTTGTACCAAAACACACACAAAAAAGGCAAACAAAACATGATAATCTGCAAAAGTTCATGTATCTACTTCATTGTGCATAGGAAGTGTTT
ACAGGTAAAATTAAAATCAAAAATTGAAAAAACACTCTTCATTTTGGCTCTCCTTTCTGAATTTTTTCAGTTTCCTGTCTCTACCCGCCA
TCCTTTGAGTGATACTATATCTGTATTGGACCAAATGTATTTACTGGTTTCATTTTGTTTATTGAATGACTTTAAATGTATTTATTATCA
TTGTTTAATTTAATGTTGGATATATTTGTATCATTACAGGAATCTGGTAATAATGGGCAAATTTAGATTGATGAGGCTTAGGGATCGGGG
ATGCTCCAGGATTCAACATTTCTTCCAATTGTTCATGGTTTGTTCTAAATTAGGACAGATTAAGAACTAATAAAACATTATTACATTTGA
ACTTGACTCAATAAAAATATTCTGATCTCCTTTATGAATATTAGGAATATTCTTTGTGATTAGTGTAAGTAGTTTGGATCAAAACATAAA
AAGAAGACCTATGGTTTATGCTACTTCTAGTTATTTGTAGTTCACAGTAAAACATGCACAGACATACACACAAACATTTTCATCAATTTC
GAATTTGAATTGTGAAAAATATATAAGAAAATAAAAACAATTTATACATTTGAGCAAATTGAGCAATCACATTTATTGCATTTATTTCCC
TTTTTCCCTTTTTTCACTCATTGAAAGTGTGGGTTTTCTAAATAATATTAGACACTAACACTCAACAGATTTATTCACAAATGACACAAG
TACACATTTTAAGACTTCTTTGTATTTCTTGCAATTATAACCAATCACTAGTCATGAAATATACCTACATAAACCAAGTCCTACACTTTC
AGTGAGGAAGAATGTAAGGAAGGTATGTTGACTGTTTTCAAGTTTCAGAAAAGATATTTTCATATGATAGGATTGAGTATCATGGGTATA
GTTTGATCTTGACATATAGTTTGAAAATCATACTCAAAAGATTTGCATTCATGAAACCAGTGAACAATAGGGTGGAATGGATGAACCATC
TCCTTGGAAGACAGGGCCCAATTTTCAATTTTTTCTTTGGCTATCAAGTTGCTAGTCACTTATTCAGGATTTTCATCCAAACTGTGTTTG
GACTGACTGTATAAGTCTTACTGCCTTTTCAGAAATCTGCTTTCCTTTGTGTGATTTTTCTTGTACTGTATAGCACGGTTTATGCACCTC
TCTTTAGATGGTGTACTTTAAAAACAAAAGTAAAATTTAGAAAATGGTTTTAACACTGCATACCTAAAATTAGTAGTGTGCAGCATTGAC
TGCCTTTGATTTGTAGTAGACAAGTAAAAATGAATACGTTCTTGTAGAATGCTGTAAAAGTTATTCAGGAATGAATACGGTTTTAGTGCC
GTAATCATGAATCTTTTTATATGAATGCACTGTCTAAAAGTGCTAAATGCATTTTCAAATTTTTAAAAATTCCTCAGATGATATATTTGA
AATGTCTAAAATAATGCTGTGCTTGAAACATTAGTGTAAAAGGAAAAAAAAAATAGTGTCACTGTGATGTTGGTCCTCCCTGTGTGGACA
CAAGTAGAAAGAAAAAACTTGGCAAGTCACCTTTGTGTACAATTTGAGGCAGTGGTTATATACAATAAATTGACCTTTATTATATCCCCC
AGACACACACATTCTTGGTGAGAAAAGAACAACCATCCAGAAATTGAGATGAGAACTTTTGTGATCTGTATGAATCACAGCAGATCATGG
GGGAGGAGGATTGGCATGCAGTGCTGTTGAAAATTGGGCTTGTTGTTAGATCAGAACAACCTCCATGTATATGGTTAGAACGAATCAATT
AATGGAATCCTAGTATTTCTGCAAGTTTGGTGATTTTTAAAAACTGGAATAGAAGCATTAATTCAGTGCTTAGTTCTAGTATTAGAAAAC
CCCTTTGATGTAATGCCTTGTATTAACCCTTTGAGCATTGTAAGATATACAATGGGGGACAAAAGCCTTTCAGATCATTTATTTAGACTT
AGACCGGTAAAGTATACTCTATATCCAAATGTCTAATTATGCTGTTTTTTTAAAGGGGGGGGTAGGAAGAGAAAGTGTTTCCACGCCGAA
CACTTGCATTTTATATACAACTCTTAATTTTTCTTCAAGAGGGCTTGATATATTTATTCCCAAATATTCACTGCCATCTAAGTAAGTGTA
CTGTTTACAGAAAAAAAAAATCAACTTTTCTAGTATCACACCATAGTCTCTAGAAAAGGAGGACAAATACATGGGCCTGGATAGACCTAT
GTCATAACTGATTTCTGCACATTGAAGGTACCTAGATTGCCTTTAAAAGGTATAAAGAAAGGGTTAAGTTTCTTTTTTTTTTGTCTTTTT
TTTCCCAAAATGAATCAAAAGATCTCATTTATTTAGCTTTAGAAAGTACAAGTGTAAGTAAAGCCTTAGGAAGAAAGGAGTTCGAGTGGA
TTAAGAGAATCTGAACTCTTTGGGGGCAGTTAGGCTATTTGGAGTTAGATCGCTCATAAAATATTGTTTGCGAATTTCACACAGGGCATA
ATTTTATCTATGCTCCAAAACTTTAATACGTTGTCAAAAAATTATATATAGATAGAATGGAGAGCAAAGCACTTGATTTTAAGCTCATCT
GTCAGGAGATGCTATGACTACTGCTTCTGATATCTCTAAATGTCAGTCTGCTTACACCATTGCTGATTTTGTTCAAGGGAATCTCTTCGT
GCACTTGATTCCCTCTGTTCCCTGCGTGATCGAACATGAAAGCAGTGTTGTCTGCAGATGTGCTTGCGCTGCCCTAGCTGGGTGCAAATA
AGAGTGTAACCTATTCTGATGTCTGGTGAAAGGACATCCATAGCATAGTGCAAGTATGCCGTAAACGTTGCTTTTTAGGCAGTTTAGGAA
GTCAGACCATGCAAATTACTCATGTGTTAACATGCAATACTCAAAGGGTTTTAATTTAACTCTCTTCTTTTGAATTCTTCATGATGATTT
ACTGTAAATGCTTCTCAGTTTGCATGCCTTGATCATTGCTGCTAGTGATTTTATGTGCCAGTAGACCTGAGTTTAGTTTACCAATTTTAC
TTAAATAGTAAAAGCCACTTACAAAGTGACTGCCTAGGATTTTTTTTTCCTTTCATTTGAAATAATTGATAATATGTTTTTTTAAAAAGA
AAAATGTGTTTTGTCTCTTCTTTTATTTGGTTCTGGTTTGATTCTTTTTCTCCCCTCTTTCCTTTGTTTTTTTTTTTTAAATAAATTATG
ATGTTGGGATTGGAAGCCCTGAGTAATGAAAATCTTTGGTAAGAATTGTTTATGTAGCTCAATAACGAGGACAACAAATATTCTTTAGAA
GAATTTTGATTCTGGGGAGGAAAGAAAATATAAAAACTCCCATTGACTGTTGATAACCAAGTAAATTTTTCCTTCAGTAAATTAGTATTT
TTGAAGAAACGATCGCCTTGTTTTAACTTGCTAAACAACAATTTTAAATGACCCAATAAAGAATCTATTGAACTTTATTCGTTTAAAAAG
CATCTTTTGTACCAAAGCAAATTTTTTTCTCTACTCATTTCCATCATCAATTTGGACCTATGGTGGTGACCAATGCATTGGTTACAGAAA
CTTTAAGTGAGTGCCTTGAGAAAACTTGGAAATTTGTGCCTGAGGTGGTAAACTTTTAATTAGGTTAATTGTAGTGCTTACCAATCAGTA
ACTTCACTATCACTCAGGGCTTTCGTACCTTCTAGGTAAAACTTCTTTCATTGTGTTTTTTTAAGATACTGTATTTTTTTTTAAGTGCCA
TCATTTAAATTTCACTTAGTAAGTGGCAGATTACATTATTCAGTCCCACAAGCACAGAAACATAGTAACACTAGGAGATATTTGAACATT
TATTTTACAATCGACTGAATATATTATGTAAATGAGGTAAGCAACTTTTGTAGAGATTGTATGTGTGAGATAATGTAATGTTCTTTTCCA
GTTTTTGGACTACAGTTGAATAAACTTTTTAATTATTTAAAAACATCTTTACCGAATAACATGTGATGGTTTTTTGTATAATGTATTTGA
TTTTGTAAATACGTATTTCCTGATGTGATTTTTGTGAGAAATGCTAAATCTTTTAGTATATCATGTCCTCTCAAAATTGGCAGGAGCTAA
ATAATAGTTTGTGGGCGATTTGTATTGTGTACTGTACAATAACTGGGGAACTTTTATAATTATAAAAATATATATTAACTTTTAGTGTGT
TGTTTAAACAAATGACTGGAACATACTAAAGATATTAGTAGGATTTTTCTGAATATTTCAGACTTGAACTCAGGCTAGCTTTCTTGTGTT

>101679_101679_2_ZNF236-RFX3_ZNF236_chr18_74659608_ENST00000320610_RFX3_chr9_3228889_ENST00000382004_length(amino acids)=1731AA_BP=983
MPRGRPPKPRESKARGDSDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTH
SGEDPTCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKI
RVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNL
QSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVI
QQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQ
ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAF
KCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITD
LGLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLIC
NGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQT
AEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPP
VQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRS
HTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPS
AVSATGETEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKHANC
CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCEL
RFRTSGRRKTHMQFHYKPDPKKARKPMTRSSSEGLQPVNLLNSSSTDPNVFIMNNSVLTGQFDQNLLQPGLVGQAILPASVSAGGDLTVS
LTDGSLATLEGIQLQLAANLVGPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPGLAPQNSSLQTSDSTVPASVVIQPI
SGLSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEITLTINNSSLSQVLAQAAGPTATSSSGSPQEITLTI
SELNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGSPQVIL
VSHTPQSASAACEEIAYQFGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEH

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Fusion Gene PPI Analysis for ZNF236-RFX3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF236-RFX3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF236-RFX3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource