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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF415-SMG9 (FusionGDB2 ID:102024)

Fusion Gene Summary for ZNF415-SMG9

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF415-SMG9
Fusion gene ID: 102024
HgeneTgene
Gene symbol

ZNF415

SMG9

Gene ID

55786

56006

Gene namezinc finger protein 415SMG9 nonsense mediated mRNA decay factor
SynonymsPact|ZfLpC19orf61|F17127_1|HBMS
Cytomap

19q13.42

19q13.31

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 415protein SMG9protein smg-9 homolog
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000440291, ENST00000596683, 
ENST00000421033, ENST00000448501, 
ENST00000594011, ENST00000595193, 
ENST00000595813, ENST00000597503, 
ENST00000599261, ENST00000243643, 
ENST00000455735, ENST00000500065, 
ENST00000597748, ENST00000600574, 
ENST00000601215, ENST00000601493, 
ENST00000270066, ENST00000601170, 
Fusion gene scores* DoF score3 X 3 X 3=277 X 4 X 7=196
# samples 38
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(8/196*10)=-1.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF415 [Title/Abstract] AND SMG9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF415(53619566)-SMG9(44244370), # samples:1
Anticipated loss of major functional domain due to fusion event.ZNF415-SMG9 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
ZNF415-SMG9 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ZNF415-SMG9 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ZNF415 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SMG9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-50-5055-01AZNF415chr19

53619566

-SMG9chr19

44244370

-


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Fusion Gene ORF analysis for ZNF415-SMG9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000440291ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
5UTR-3CDSENST00000440291ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
5UTR-3CDSENST00000596683ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
5UTR-3CDSENST00000596683ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000421033ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000421033ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000448501ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000448501ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000594011ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000594011ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000595193ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000595193ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000595813ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000595813ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000597503ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000597503ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000599261ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
Frame-shiftENST00000599261ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
In-frameENST00000243643ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
In-frameENST00000243643ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
In-frameENST00000455735ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
In-frameENST00000455735ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
In-frameENST00000500065ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
In-frameENST00000500065ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
In-frameENST00000597748ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
In-frameENST00000597748ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
intron-3CDSENST00000600574ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
intron-3CDSENST00000600574ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
intron-3CDSENST00000601215ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
intron-3CDSENST00000601215ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-
intron-3CDSENST00000601493ENST00000270066ZNF415chr19

53619566

-SMG9chr19

44244370

-
intron-3CDSENST00000601493ENST00000601170ZNF415chr19

53619566

-SMG9chr19

44244370

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000243643ZNF415chr1953619566-ENST00000270066SMG9chr1944244370-15492401661101311
ENST00000243643ZNF415chr1953619566-ENST00000601170SMG9chr1944244370-16112401661026286
ENST00000455735ZNF415chr1953619566-ENST00000270066SMG9chr1944244370-17043953211256311
ENST00000455735ZNF415chr1953619566-ENST00000601170SMG9chr1944244370-17663953211181286
ENST00000500065ZNF415chr1953619566-ENST00000270066SMG9chr1944244370-17794703961331311
ENST00000500065ZNF415chr1953619566-ENST00000601170SMG9chr1944244370-18414703961256286
ENST00000597748ZNF415chr1953619566-ENST00000270066SMG9chr1944244370-16613522781213311
ENST00000597748ZNF415chr1953619566-ENST00000601170SMG9chr1944244370-17233522781138286

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000243643ENST00000270066ZNF415chr1953619566-SMG9chr1944244370-0.0029134830.9970866
ENST00000243643ENST00000601170ZNF415chr1953619566-SMG9chr1944244370-0.0025884860.99741155
ENST00000455735ENST00000270066ZNF415chr1953619566-SMG9chr1944244370-0.005319240.9946807
ENST00000455735ENST00000601170ZNF415chr1953619566-SMG9chr1944244370-0.0051822550.9948178
ENST00000500065ENST00000270066ZNF415chr1953619566-SMG9chr1944244370-0.0038147890.99618524
ENST00000500065ENST00000601170ZNF415chr1953619566-SMG9chr1944244370-0.003463440.9965366
ENST00000597748ENST00000270066ZNF415chr1953619566-SMG9chr1944244370-0.0049856130.99501437
ENST00000597748ENST00000601170ZNF415chr1953619566-SMG9chr1944244370-0.004808910.9951911

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Fusion Genomic Features for ZNF415-SMG9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZNF415-SMG9


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:53619566/chr19:44244370)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34264_28645556.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34292_31445556.0Zinc fingerC2H2-type 2
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34320_34245556.0Zinc fingerC2H2-type 3
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34348_37045556.0Zinc fingerC2H2-type 4
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34376_39845556.0Zinc fingerC2H2-type 5
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34404_42645556.0Zinc fingerC2H2-type 6
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34432_45445556.0Zinc fingerC2H2-type 7
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34460_48245556.0Zinc fingerC2H2-type 8
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34488_51045556.0Zinc fingerC2H2-type 9
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34516_53845556.0Zinc fingerC2H2-type 10
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34544_56645556.0Zinc fingerC2H2-type 11
HgeneZNF415chr19:53619566chr19:44244370ENST00000243643-34572_59445556.0Zinc fingerC2H2-type 12
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35264_28624568.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35292_31424568.0Zinc fingerC2H2-type 2
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35320_34224568.0Zinc fingerC2H2-type 3
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35348_37024568.0Zinc fingerC2H2-type 4
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35376_39824568.0Zinc fingerC2H2-type 5
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35404_42624568.0Zinc fingerC2H2-type 6
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35432_45424568.0Zinc fingerC2H2-type 7
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35460_48224568.0Zinc fingerC2H2-type 8
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35488_51024568.0Zinc fingerC2H2-type 9
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35516_53824568.0Zinc fingerC2H2-type 10
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35544_56624568.0Zinc fingerC2H2-type 11
HgeneZNF415chr19:53619566chr19:44244370ENST00000421033-35572_59424568.0Zinc fingerC2H2-type 12
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35264_2860543.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35292_3140543.0Zinc fingerC2H2-type 2
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35320_3420543.0Zinc fingerC2H2-type 3
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35348_3700543.0Zinc fingerC2H2-type 4
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35376_3980543.0Zinc fingerC2H2-type 5
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35404_4260543.0Zinc fingerC2H2-type 6
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35432_4540543.0Zinc fingerC2H2-type 7
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35460_4820543.0Zinc fingerC2H2-type 8
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35488_5100543.0Zinc fingerC2H2-type 9
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35516_5380543.0Zinc fingerC2H2-type 10
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35544_5660543.0Zinc fingerC2H2-type 11
HgeneZNF415chr19:53619566chr19:44244370ENST00000440291-35572_5940543.0Zinc fingerC2H2-type 12
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34264_28645556.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34292_31445556.0Zinc fingerC2H2-type 2
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34320_34245556.0Zinc fingerC2H2-type 3
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34348_37045556.0Zinc fingerC2H2-type 4
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34376_39845556.0Zinc fingerC2H2-type 5
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34404_42645556.0Zinc fingerC2H2-type 6
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34432_45445556.0Zinc fingerC2H2-type 7
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34460_48245556.0Zinc fingerC2H2-type 8
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34488_51045556.0Zinc fingerC2H2-type 9
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34516_53845556.0Zinc fingerC2H2-type 10
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34544_56645556.0Zinc fingerC2H2-type 11
HgeneZNF415chr19:53619566chr19:44244370ENST00000500065-34572_59445556.0Zinc fingerC2H2-type 12
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13264_2860326.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13292_3140326.0Zinc fingerC2H2-type 2
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13320_3420326.0Zinc fingerC2H2-type 3
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13348_3700326.0Zinc fingerC2H2-type 4
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13376_3980326.0Zinc fingerC2H2-type 5
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13404_4260326.0Zinc fingerC2H2-type 6
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13432_4540326.0Zinc fingerC2H2-type 7
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13460_4820326.0Zinc fingerC2H2-type 8
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13488_5100326.0Zinc fingerC2H2-type 9
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13516_5380326.0Zinc fingerC2H2-type 10
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13544_5660326.0Zinc fingerC2H2-type 11
HgeneZNF415chr19:53619566chr19:44244370ENST00000601493-13572_5940326.0Zinc fingerC2H2-type 12
TgeneSMG9chr19:53619566chr19:44244370ENST0000027006651471_133233521.0Compositional biasNote=Pro-rich
TgeneSMG9chr19:53619566chr19:44244370ENST0000060117051371_133233496.0Compositional biasNote=Pro-rich


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Fusion Gene Sequence for ZNF415-SMG9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102024_102024_1_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000243643_SMG9_chr19_44244370_ENST00000270066_length(transcript)=1549nt_BP=240nt
AAACGGATCGCGTTGGGTGAAGGTGACGGCGTCGAGCCATTGACTTCCAAAGACTCCTGGCACATGAGGAAGAAACCCAGAAGAGGAGAG
CAAAGGAGTCAGGAATGGCTTTTACTCAGTTGACATTCAGGGACGTGGCCATCGAATTCTCTCAAGATGAGTGGAAATGCCTGAACTCTA
CACAGAGGACTTTATACAGGGATGTGATGTTGGAGAACTACAGGAACCTGGTCTCCCTGGGACTTATGTTTTCCGGGCCCAGAGCGCTGA
AATGAAGGAACGAGGGGGCAACCAGACCAGTGGCATCGACTTCTTTATTACCCAAGAACGGATTGTTTTCCTGGACACACAGCCCATCCT
GAGCCCTTCTATCCTAGACCATCTCATCAATAATGACCGCAAACTGCCTCCAGAGTACAACCTTCCCCACACTTACGTTGAAATGCAGTC
ACTCCAGATTGCTGCCTTCCTTTTCACGGTCTGCCATGTGGTGATTGTTGTCCAGGACTGGTTCACAGACCTCAGTCTCTACAGGTTCCT
GCAGACAGCAGAGATGGTGAAGCCCTCCACCCCATCCCCCAGCCACGAGTCCAGCAGCTCATCGGGCTCCGATGAAGGCACCGAGTACTA
CCCCCACCTAGTCTTCTTGCAGAACAAAGCTCGCCGAGAGGACTTCTGTCCTCGGAAGCTGCGGCAGATGCACCTGATGATTGACCAGCT
CATGGCCCACTCCCACCTGCGTTACAAGGGAACTCTGTCCATGTTACAATGCAATGTCTTCCCGGGGCTTCCACCTGACTTCCTGGACTC
TGAGGTCAACTTATTCCTGGTACCCTTCATGGACAGTGAAGCAGAGAGTGAAAACCCACCAAGAGCAGGACCTGGTTCCAGCCCACTCTT
CTCCCTGCTGCCTGGGTATCGTGGCCACCCCAGTTTCCAGTCCTTGGTGAGCAAGCTCCGGAGCCAAGTGATGTCCATGGCCCGGCCACA
GCTGTCACACACGATCCTCACCGAGAAGAACTGGTTCCACTACGCTGCCCGGATCTGGGATGGGGTGAGAAAGTCCTCTGCTCTGGCAGA
GTACAGCCGCCTGCTGGCCTGAGGCCAAGGAGAGGAATGTCATGCAGGGGACCTCCTGGGTCCGCAGTGTACTGCGAGGGAGCACAGATG
TCCATCCCCCGCTGGGGTGGAGAGCGGCAGCAGGCCTGATGGATGAGGGATCGTGGCTTCCCGGCCCAGAGACATGAGGTGTCCAGGGCC
AGGCCCCCCACCCTCAGTTGGGGCTGTTCCGGGGGTGACTGTGAGCGATCCCACCCCAAACCTGAGATGGGGTAGCCCGTCCTGTGTCCT
CCACAGGGACAAGCAGTGGGAGGAGTCTGAATGGTCACCAGGAAGCCCGGGCTCCATCTTGACCTCCTTTTTCAGGGACAGGAGCAACAG
GCCCCTCTTCCCTGACTCTAAGCCCTTCCCTGTAAGGTGAGGCAGGGTCTGGAGAGCTCTTTATTGGAACAGATCTGGTGGTTCAAATAA

>102024_102024_1_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000243643_SMG9_chr19_44244370_ENST00000270066_length(amino acids)=311AA_BP=20
MPELYTEDFIQGCDVGELQEPGLPGTYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTY
VEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSSGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHL
MIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDSEVNLFLVPFMDSEAESENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMS

--------------------------------------------------------------
>102024_102024_2_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000243643_SMG9_chr19_44244370_ENST00000601170_length(transcript)=1611nt_BP=240nt
AAACGGATCGCGTTGGGTGAAGGTGACGGCGTCGAGCCATTGACTTCCAAAGACTCCTGGCACATGAGGAAGAAACCCAGAAGAGGAGAG
CAAAGGAGTCAGGAATGGCTTTTACTCAGTTGACATTCAGGGACGTGGCCATCGAATTCTCTCAAGATGAGTGGAAATGCCTGAACTCTA
CACAGAGGACTTTATACAGGGATGTGATGTTGGAGAACTACAGGAACCTGGTCTCCCTGGGACTTATGTTTTCCGGGCCCAGAGCGCTGA
AATGAAGGAACGAGGGGGCAACCAGACCAGTGGCATCGACTTCTTTATTACCCAAGAACGGATTGTTTTCCTGGACACACAGCCCATCCT
GAGCCCTTCTATCCTAGACCATCTCATCAATAATGACCGCAAACTGCCTCCAGAGTACAACCTTCCCCACACTTACGTTGAAATGCAGTC
ACTCCAGATTGCTGCCTTCCTTTTCACGGTCTGCCATGTGGTGATTGTTGTCCAGGACTGGTTCACAGACCTCAGTCTCTACAGGTTCCT
GCAGACAGCAGAGATGGTGAAGCCCTCCACCCCATCCCCCAGCCACGAGTCCAGCAGCTCATCGGGCTCCGATGAAGGCACCGAGTACTA
CCCCCACCTAGTCTTCTTGCAGAACAAAGCTCGCCGAGAGGACTTCTGTCCTCGGAAGCTGCGGCAGATGCACCTGATGATTGACCAGCT
CATGGCCCACTCCCACCTGCGTTACAAGGGAACTCTGTCCATGTTACAATGCAATGTCTTCCCGGGGCTTCCACCTGACTTCCTGGACTC
TGAGGTCAACTTATTCCTGGTACCCTTCATGGACAGTGAAGCAGAGAGTGAAAACCCACCAAGAGCAGGACCTGGTTCCAGCCCACTCTT
CTCCCTGCTGCCTGGGTATCGTGGCCACCCCAGTTTCCAGTCCTTGGTGAGCAAGCTCCGGAGCCAAGTGATGTCCATGGCCCGGCCACA
GCTGTCACACACGATCCTCACCGAGAAGAACTGGTAAGAGCTCTTTGCAGAGGGGGTCAATTTGAGGCACCCCACCCTGGTGTAGAGAGA
AGGGGGCGTCCCTTAGATCGGCATGACCTTGTGAAGCCCCTCCTCTCCAGATCCCAGGTTCCTTTTCTGGAACAGTGATGATTGCTACTG
TCTTGTAAGCATCTCACCCATGTGGCAACATGCTGTTTCCTGTGACTTTGAATCCTCCTAATCAGCCAGCATCATGTAGGTCCTTGTCAC
CAGTTTTCCTGGTGGGGAAATTTAGGCTCGGGGAAAAGTGTTACATAGCAAGGCCACACATCTGTGGCTAGGAGTCATTTGATTGCTAGG
AGTAGGACCAGTGACCAGATTTAGCTTAAGGAAGATTTATTCCAGGGACCTGATCACAGAAAGCAGGGCCCTGCAGCAGATGGGAACCAG
GAAGCCATCAGGGTCTCATTCTTCACACTTCTGCATTTGTCTTGTTTCCTGCCTCTGGCTTTCTCTCCCTGCTTTCACTTGGCCCGGCAC

>102024_102024_2_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000243643_SMG9_chr19_44244370_ENST00000601170_length(amino acids)=286AA_BP=20
MPELYTEDFIQGCDVGELQEPGLPGTYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTY
VEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSSGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHL
MIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDSEVNLFLVPFMDSEAESENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMS

--------------------------------------------------------------
>102024_102024_3_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000455735_SMG9_chr19_44244370_ENST00000270066_length(transcript)=1704nt_BP=395nt
AAACGGATCGCGTTGGGTGAAGGTGACGGCGTCGAGCGACCTCTCTGACCTCATCTCCTGCCTGTGTCCTCCTCGCTCCCTCTGCTCCAG
CCAAGCATGCGTCCTTCCTGTTCCTGGGCCGAGCTTGCTCCTGCCTCAAGGCCTTCACGTGGGCTGTGCCTCTGCTGGAACTCGCTGGCC
CCTCAGCTGCAGCATTGACTTCCAAAGACTCCTGGCACATGAGGAAGAAACCCAGAAGAGGAGAGCAAAGGAGTCAGGAATGGCTTTTAC
TCAGTTGACATTCAGGGACGTGGCCATCGAATTCTCTCAAGATGAGTGGAAATGCCTGAACTCTACACAGAGGACTTTATACAGGGATGT
GATGTTGGAGAACTACAGGAACCTGGTCTCCCTGGGACTTATGTTTTCCGGGCCCAGAGCGCTGAAATGAAGGAACGAGGGGGCAACCAG
ACCAGTGGCATCGACTTCTTTATTACCCAAGAACGGATTGTTTTCCTGGACACACAGCCCATCCTGAGCCCTTCTATCCTAGACCATCTC
ATCAATAATGACCGCAAACTGCCTCCAGAGTACAACCTTCCCCACACTTACGTTGAAATGCAGTCACTCCAGATTGCTGCCTTCCTTTTC
ACGGTCTGCCATGTGGTGATTGTTGTCCAGGACTGGTTCACAGACCTCAGTCTCTACAGGTTCCTGCAGACAGCAGAGATGGTGAAGCCC
TCCACCCCATCCCCCAGCCACGAGTCCAGCAGCTCATCGGGCTCCGATGAAGGCACCGAGTACTACCCCCACCTAGTCTTCTTGCAGAAC
AAAGCTCGCCGAGAGGACTTCTGTCCTCGGAAGCTGCGGCAGATGCACCTGATGATTGACCAGCTCATGGCCCACTCCCACCTGCGTTAC
AAGGGAACTCTGTCCATGTTACAATGCAATGTCTTCCCGGGGCTTCCACCTGACTTCCTGGACTCTGAGGTCAACTTATTCCTGGTACCC
TTCATGGACAGTGAAGCAGAGAGTGAAAACCCACCAAGAGCAGGACCTGGTTCCAGCCCACTCTTCTCCCTGCTGCCTGGGTATCGTGGC
CACCCCAGTTTCCAGTCCTTGGTGAGCAAGCTCCGGAGCCAAGTGATGTCCATGGCCCGGCCACAGCTGTCACACACGATCCTCACCGAG
AAGAACTGGTTCCACTACGCTGCCCGGATCTGGGATGGGGTGAGAAAGTCCTCTGCTCTGGCAGAGTACAGCCGCCTGCTGGCCTGAGGC
CAAGGAGAGGAATGTCATGCAGGGGACCTCCTGGGTCCGCAGTGTACTGCGAGGGAGCACAGATGTCCATCCCCCGCTGGGGTGGAGAGC
GGCAGCAGGCCTGATGGATGAGGGATCGTGGCTTCCCGGCCCAGAGACATGAGGTGTCCAGGGCCAGGCCCCCCACCCTCAGTTGGGGCT
GTTCCGGGGGTGACTGTGAGCGATCCCACCCCAAACCTGAGATGGGGTAGCCCGTCCTGTGTCCTCCACAGGGACAAGCAGTGGGAGGAG
TCTGAATGGTCACCAGGAAGCCCGGGCTCCATCTTGACCTCCTTTTTCAGGGACAGGAGCAACAGGCCCCTCTTCCCTGACTCTAAGCCC

>102024_102024_3_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000455735_SMG9_chr19_44244370_ENST00000270066_length(amino acids)=311AA_BP=20
MPELYTEDFIQGCDVGELQEPGLPGTYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTY
VEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSSGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHL
MIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDSEVNLFLVPFMDSEAESENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMS

--------------------------------------------------------------
>102024_102024_4_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000455735_SMG9_chr19_44244370_ENST00000601170_length(transcript)=1766nt_BP=395nt
AAACGGATCGCGTTGGGTGAAGGTGACGGCGTCGAGCGACCTCTCTGACCTCATCTCCTGCCTGTGTCCTCCTCGCTCCCTCTGCTCCAG
CCAAGCATGCGTCCTTCCTGTTCCTGGGCCGAGCTTGCTCCTGCCTCAAGGCCTTCACGTGGGCTGTGCCTCTGCTGGAACTCGCTGGCC
CCTCAGCTGCAGCATTGACTTCCAAAGACTCCTGGCACATGAGGAAGAAACCCAGAAGAGGAGAGCAAAGGAGTCAGGAATGGCTTTTAC
TCAGTTGACATTCAGGGACGTGGCCATCGAATTCTCTCAAGATGAGTGGAAATGCCTGAACTCTACACAGAGGACTTTATACAGGGATGT
GATGTTGGAGAACTACAGGAACCTGGTCTCCCTGGGACTTATGTTTTCCGGGCCCAGAGCGCTGAAATGAAGGAACGAGGGGGCAACCAG
ACCAGTGGCATCGACTTCTTTATTACCCAAGAACGGATTGTTTTCCTGGACACACAGCCCATCCTGAGCCCTTCTATCCTAGACCATCTC
ATCAATAATGACCGCAAACTGCCTCCAGAGTACAACCTTCCCCACACTTACGTTGAAATGCAGTCACTCCAGATTGCTGCCTTCCTTTTC
ACGGTCTGCCATGTGGTGATTGTTGTCCAGGACTGGTTCACAGACCTCAGTCTCTACAGGTTCCTGCAGACAGCAGAGATGGTGAAGCCC
TCCACCCCATCCCCCAGCCACGAGTCCAGCAGCTCATCGGGCTCCGATGAAGGCACCGAGTACTACCCCCACCTAGTCTTCTTGCAGAAC
AAAGCTCGCCGAGAGGACTTCTGTCCTCGGAAGCTGCGGCAGATGCACCTGATGATTGACCAGCTCATGGCCCACTCCCACCTGCGTTAC
AAGGGAACTCTGTCCATGTTACAATGCAATGTCTTCCCGGGGCTTCCACCTGACTTCCTGGACTCTGAGGTCAACTTATTCCTGGTACCC
TTCATGGACAGTGAAGCAGAGAGTGAAAACCCACCAAGAGCAGGACCTGGTTCCAGCCCACTCTTCTCCCTGCTGCCTGGGTATCGTGGC
CACCCCAGTTTCCAGTCCTTGGTGAGCAAGCTCCGGAGCCAAGTGATGTCCATGGCCCGGCCACAGCTGTCACACACGATCCTCACCGAG
AAGAACTGGTAAGAGCTCTTTGCAGAGGGGGTCAATTTGAGGCACCCCACCCTGGTGTAGAGAGAAGGGGGCGTCCCTTAGATCGGCATG
ACCTTGTGAAGCCCCTCCTCTCCAGATCCCAGGTTCCTTTTCTGGAACAGTGATGATTGCTACTGTCTTGTAAGCATCTCACCCATGTGG
CAACATGCTGTTTCCTGTGACTTTGAATCCTCCTAATCAGCCAGCATCATGTAGGTCCTTGTCACCAGTTTTCCTGGTGGGGAAATTTAG
GCTCGGGGAAAAGTGTTACATAGCAAGGCCACACATCTGTGGCTAGGAGTCATTTGATTGCTAGGAGTAGGACCAGTGACCAGATTTAGC
TTAAGGAAGATTTATTCCAGGGACCTGATCACAGAAAGCAGGGCCCTGCAGCAGATGGGAACCAGGAAGCCATCAGGGTCTCATTCTTCA
CACTTCTGCATTTGTCTTGTTTCCTGCCTCTGGCTTTCTCTCCCTGCTTTCACTTGGCCCGGCACTAGCTCTGTGGCCCCTACTTTACAT

>102024_102024_4_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000455735_SMG9_chr19_44244370_ENST00000601170_length(amino acids)=286AA_BP=20
MPELYTEDFIQGCDVGELQEPGLPGTYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTY
VEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSSGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHL
MIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDSEVNLFLVPFMDSEAESENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMS

--------------------------------------------------------------
>102024_102024_5_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000500065_SMG9_chr19_44244370_ENST00000270066_length(transcript)=1779nt_BP=470nt
GGATCGCGTTGGGTGAAGGTGACGGCGTCGAGCGTGAGTGACCCTCTGTGTAGATTAAACCTGCGCTCCCTGTTTCCCATTTCCACAGCC
GATGTCCAGGGTCGATACGGCCCTTAAAATCCCCGTACACTCCACCCCAGGTGGGAGACAATGCCTTGGAGCTGCAAATCTTCTCTGAGT
CTGAAGCATCCTGCCTGACGCGTTTGCTCACATTGACCCGTGCCTTCCCTCAGTCCTTCTCATCTCTACTGAGATTCCGTCTCACCCTGA
CCCTGTGACATGAACTTCTGAAGAGTCCACTGGGCATGGTCCTGGGAAGGGCTCACACCCAGACATGGATGGAGACGGGTTGACATTCAG
GGACGTGGCCATCGAATTCTCTCAAGATGAGTGGAAATGCCTGAACTCTACACAGAGGACTTTATACAGGGATGTGATGTTGGAGAACTA
CAGGAACCTGGTCTCCCTGGGACTTATGTTTTCCGGGCCCAGAGCGCTGAAATGAAGGAACGAGGGGGCAACCAGACCAGTGGCATCGAC
TTCTTTATTACCCAAGAACGGATTGTTTTCCTGGACACACAGCCCATCCTGAGCCCTTCTATCCTAGACCATCTCATCAATAATGACCGC
AAACTGCCTCCAGAGTACAACCTTCCCCACACTTACGTTGAAATGCAGTCACTCCAGATTGCTGCCTTCCTTTTCACGGTCTGCCATGTG
GTGATTGTTGTCCAGGACTGGTTCACAGACCTCAGTCTCTACAGGTTCCTGCAGACAGCAGAGATGGTGAAGCCCTCCACCCCATCCCCC
AGCCACGAGTCCAGCAGCTCATCGGGCTCCGATGAAGGCACCGAGTACTACCCCCACCTAGTCTTCTTGCAGAACAAAGCTCGCCGAGAG
GACTTCTGTCCTCGGAAGCTGCGGCAGATGCACCTGATGATTGACCAGCTCATGGCCCACTCCCACCTGCGTTACAAGGGAACTCTGTCC
ATGTTACAATGCAATGTCTTCCCGGGGCTTCCACCTGACTTCCTGGACTCTGAGGTCAACTTATTCCTGGTACCCTTCATGGACAGTGAA
GCAGAGAGTGAAAACCCACCAAGAGCAGGACCTGGTTCCAGCCCACTCTTCTCCCTGCTGCCTGGGTATCGTGGCCACCCCAGTTTCCAG
TCCTTGGTGAGCAAGCTCCGGAGCCAAGTGATGTCCATGGCCCGGCCACAGCTGTCACACACGATCCTCACCGAGAAGAACTGGTTCCAC
TACGCTGCCCGGATCTGGGATGGGGTGAGAAAGTCCTCTGCTCTGGCAGAGTACAGCCGCCTGCTGGCCTGAGGCCAAGGAGAGGAATGT
CATGCAGGGGACCTCCTGGGTCCGCAGTGTACTGCGAGGGAGCACAGATGTCCATCCCCCGCTGGGGTGGAGAGCGGCAGCAGGCCTGAT
GGATGAGGGATCGTGGCTTCCCGGCCCAGAGACATGAGGTGTCCAGGGCCAGGCCCCCCACCCTCAGTTGGGGCTGTTCCGGGGGTGACT
GTGAGCGATCCCACCCCAAACCTGAGATGGGGTAGCCCGTCCTGTGTCCTCCACAGGGACAAGCAGTGGGAGGAGTCTGAATGGTCACCA
GGAAGCCCGGGCTCCATCTTGACCTCCTTTTTCAGGGACAGGAGCAACAGGCCCCTCTTCCCTGACTCTAAGCCCTTCCCTGTAAGGTGA

>102024_102024_5_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000500065_SMG9_chr19_44244370_ENST00000270066_length(amino acids)=311AA_BP=20
MPELYTEDFIQGCDVGELQEPGLPGTYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTY
VEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSSGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHL
MIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDSEVNLFLVPFMDSEAESENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMS

--------------------------------------------------------------
>102024_102024_6_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000500065_SMG9_chr19_44244370_ENST00000601170_length(transcript)=1841nt_BP=470nt
GGATCGCGTTGGGTGAAGGTGACGGCGTCGAGCGTGAGTGACCCTCTGTGTAGATTAAACCTGCGCTCCCTGTTTCCCATTTCCACAGCC
GATGTCCAGGGTCGATACGGCCCTTAAAATCCCCGTACACTCCACCCCAGGTGGGAGACAATGCCTTGGAGCTGCAAATCTTCTCTGAGT
CTGAAGCATCCTGCCTGACGCGTTTGCTCACATTGACCCGTGCCTTCCCTCAGTCCTTCTCATCTCTACTGAGATTCCGTCTCACCCTGA
CCCTGTGACATGAACTTCTGAAGAGTCCACTGGGCATGGTCCTGGGAAGGGCTCACACCCAGACATGGATGGAGACGGGTTGACATTCAG
GGACGTGGCCATCGAATTCTCTCAAGATGAGTGGAAATGCCTGAACTCTACACAGAGGACTTTATACAGGGATGTGATGTTGGAGAACTA
CAGGAACCTGGTCTCCCTGGGACTTATGTTTTCCGGGCCCAGAGCGCTGAAATGAAGGAACGAGGGGGCAACCAGACCAGTGGCATCGAC
TTCTTTATTACCCAAGAACGGATTGTTTTCCTGGACACACAGCCCATCCTGAGCCCTTCTATCCTAGACCATCTCATCAATAATGACCGC
AAACTGCCTCCAGAGTACAACCTTCCCCACACTTACGTTGAAATGCAGTCACTCCAGATTGCTGCCTTCCTTTTCACGGTCTGCCATGTG
GTGATTGTTGTCCAGGACTGGTTCACAGACCTCAGTCTCTACAGGTTCCTGCAGACAGCAGAGATGGTGAAGCCCTCCACCCCATCCCCC
AGCCACGAGTCCAGCAGCTCATCGGGCTCCGATGAAGGCACCGAGTACTACCCCCACCTAGTCTTCTTGCAGAACAAAGCTCGCCGAGAG
GACTTCTGTCCTCGGAAGCTGCGGCAGATGCACCTGATGATTGACCAGCTCATGGCCCACTCCCACCTGCGTTACAAGGGAACTCTGTCC
ATGTTACAATGCAATGTCTTCCCGGGGCTTCCACCTGACTTCCTGGACTCTGAGGTCAACTTATTCCTGGTACCCTTCATGGACAGTGAA
GCAGAGAGTGAAAACCCACCAAGAGCAGGACCTGGTTCCAGCCCACTCTTCTCCCTGCTGCCTGGGTATCGTGGCCACCCCAGTTTCCAG
TCCTTGGTGAGCAAGCTCCGGAGCCAAGTGATGTCCATGGCCCGGCCACAGCTGTCACACACGATCCTCACCGAGAAGAACTGGTAAGAG
CTCTTTGCAGAGGGGGTCAATTTGAGGCACCCCACCCTGGTGTAGAGAGAAGGGGGCGTCCCTTAGATCGGCATGACCTTGTGAAGCCCC
TCCTCTCCAGATCCCAGGTTCCTTTTCTGGAACAGTGATGATTGCTACTGTCTTGTAAGCATCTCACCCATGTGGCAACATGCTGTTTCC
TGTGACTTTGAATCCTCCTAATCAGCCAGCATCATGTAGGTCCTTGTCACCAGTTTTCCTGGTGGGGAAATTTAGGCTCGGGGAAAAGTG
TTACATAGCAAGGCCACACATCTGTGGCTAGGAGTCATTTGATTGCTAGGAGTAGGACCAGTGACCAGATTTAGCTTAAGGAAGATTTAT
TCCAGGGACCTGATCACAGAAAGCAGGGCCCTGCAGCAGATGGGAACCAGGAAGCCATCAGGGTCTCATTCTTCACACTTCTGCATTTGT
CTTGTTTCCTGCCTCTGGCTTTCTCTCCCTGCTTTCACTTGGCCCGGCACTAGCTCTGTGGCCCCTACTTTACATTACTTCTTTGTCCAG

>102024_102024_6_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000500065_SMG9_chr19_44244370_ENST00000601170_length(amino acids)=286AA_BP=20
MPELYTEDFIQGCDVGELQEPGLPGTYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTY
VEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSSGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHL
MIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDSEVNLFLVPFMDSEAESENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMS

--------------------------------------------------------------
>102024_102024_7_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000597748_SMG9_chr19_44244370_ENST00000270066_length(transcript)=1661nt_BP=352nt
TCTGACCTCATCTCCTGCCTGTGTCCTCCTCGCTCCCTCTGCTCCAGCCAAGCATGCGTCCTTCCTGTTCCTGGGCCGAGCTTGCTCCTG
CCTCAAGGCCTTCACGTGGGCTGTGCCTCTGCTGGAACTCGCTGGCCCCTCAGCTGCAGCATTGACTTCCAAAGACTCCTGGCACATGAG
GAAGAAACCCAGAAGAGGAGAGCAAAGGAGTCAGGAATGGCTTTTACTCAGTTGACATTCAGGGACGTGGCCATCGAATTCTCTCAAGAT
GAGTGGAAATGCCTGAACTCTACACAGAGGACTTTATACAGGGATGTGATGTTGGAGAACTACAGGAACCTGGTCTCCCTGGGACTTATG
TTTTCCGGGCCCAGAGCGCTGAAATGAAGGAACGAGGGGGCAACCAGACCAGTGGCATCGACTTCTTTATTACCCAAGAACGGATTGTTT
TCCTGGACACACAGCCCATCCTGAGCCCTTCTATCCTAGACCATCTCATCAATAATGACCGCAAACTGCCTCCAGAGTACAACCTTCCCC
ACACTTACGTTGAAATGCAGTCACTCCAGATTGCTGCCTTCCTTTTCACGGTCTGCCATGTGGTGATTGTTGTCCAGGACTGGTTCACAG
ACCTCAGTCTCTACAGGTTCCTGCAGACAGCAGAGATGGTGAAGCCCTCCACCCCATCCCCCAGCCACGAGTCCAGCAGCTCATCGGGCT
CCGATGAAGGCACCGAGTACTACCCCCACCTAGTCTTCTTGCAGAACAAAGCTCGCCGAGAGGACTTCTGTCCTCGGAAGCTGCGGCAGA
TGCACCTGATGATTGACCAGCTCATGGCCCACTCCCACCTGCGTTACAAGGGAACTCTGTCCATGTTACAATGCAATGTCTTCCCGGGGC
TTCCACCTGACTTCCTGGACTCTGAGGTCAACTTATTCCTGGTACCCTTCATGGACAGTGAAGCAGAGAGTGAAAACCCACCAAGAGCAG
GACCTGGTTCCAGCCCACTCTTCTCCCTGCTGCCTGGGTATCGTGGCCACCCCAGTTTCCAGTCCTTGGTGAGCAAGCTCCGGAGCCAAG
TGATGTCCATGGCCCGGCCACAGCTGTCACACACGATCCTCACCGAGAAGAACTGGTTCCACTACGCTGCCCGGATCTGGGATGGGGTGA
GAAAGTCCTCTGCTCTGGCAGAGTACAGCCGCCTGCTGGCCTGAGGCCAAGGAGAGGAATGTCATGCAGGGGACCTCCTGGGTCCGCAGT
GTACTGCGAGGGAGCACAGATGTCCATCCCCCGCTGGGGTGGAGAGCGGCAGCAGGCCTGATGGATGAGGGATCGTGGCTTCCCGGCCCA
GAGACATGAGGTGTCCAGGGCCAGGCCCCCCACCCTCAGTTGGGGCTGTTCCGGGGGTGACTGTGAGCGATCCCACCCCAAACCTGAGAT
GGGGTAGCCCGTCCTGTGTCCTCCACAGGGACAAGCAGTGGGAGGAGTCTGAATGGTCACCAGGAAGCCCGGGCTCCATCTTGACCTCCT
TTTTCAGGGACAGGAGCAACAGGCCCCTCTTCCCTGACTCTAAGCCCTTCCCTGTAAGGTGAGGCAGGGTCTGGAGAGCTCTTTATTGGA

>102024_102024_7_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000597748_SMG9_chr19_44244370_ENST00000270066_length(amino acids)=311AA_BP=20
MPELYTEDFIQGCDVGELQEPGLPGTYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTY
VEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSSGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHL
MIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDSEVNLFLVPFMDSEAESENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMS

--------------------------------------------------------------
>102024_102024_8_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000597748_SMG9_chr19_44244370_ENST00000601170_length(transcript)=1723nt_BP=352nt
TCTGACCTCATCTCCTGCCTGTGTCCTCCTCGCTCCCTCTGCTCCAGCCAAGCATGCGTCCTTCCTGTTCCTGGGCCGAGCTTGCTCCTG
CCTCAAGGCCTTCACGTGGGCTGTGCCTCTGCTGGAACTCGCTGGCCCCTCAGCTGCAGCATTGACTTCCAAAGACTCCTGGCACATGAG
GAAGAAACCCAGAAGAGGAGAGCAAAGGAGTCAGGAATGGCTTTTACTCAGTTGACATTCAGGGACGTGGCCATCGAATTCTCTCAAGAT
GAGTGGAAATGCCTGAACTCTACACAGAGGACTTTATACAGGGATGTGATGTTGGAGAACTACAGGAACCTGGTCTCCCTGGGACTTATG
TTTTCCGGGCCCAGAGCGCTGAAATGAAGGAACGAGGGGGCAACCAGACCAGTGGCATCGACTTCTTTATTACCCAAGAACGGATTGTTT
TCCTGGACACACAGCCCATCCTGAGCCCTTCTATCCTAGACCATCTCATCAATAATGACCGCAAACTGCCTCCAGAGTACAACCTTCCCC
ACACTTACGTTGAAATGCAGTCACTCCAGATTGCTGCCTTCCTTTTCACGGTCTGCCATGTGGTGATTGTTGTCCAGGACTGGTTCACAG
ACCTCAGTCTCTACAGGTTCCTGCAGACAGCAGAGATGGTGAAGCCCTCCACCCCATCCCCCAGCCACGAGTCCAGCAGCTCATCGGGCT
CCGATGAAGGCACCGAGTACTACCCCCACCTAGTCTTCTTGCAGAACAAAGCTCGCCGAGAGGACTTCTGTCCTCGGAAGCTGCGGCAGA
TGCACCTGATGATTGACCAGCTCATGGCCCACTCCCACCTGCGTTACAAGGGAACTCTGTCCATGTTACAATGCAATGTCTTCCCGGGGC
TTCCACCTGACTTCCTGGACTCTGAGGTCAACTTATTCCTGGTACCCTTCATGGACAGTGAAGCAGAGAGTGAAAACCCACCAAGAGCAG
GACCTGGTTCCAGCCCACTCTTCTCCCTGCTGCCTGGGTATCGTGGCCACCCCAGTTTCCAGTCCTTGGTGAGCAAGCTCCGGAGCCAAG
TGATGTCCATGGCCCGGCCACAGCTGTCACACACGATCCTCACCGAGAAGAACTGGTAAGAGCTCTTTGCAGAGGGGGTCAATTTGAGGC
ACCCCACCCTGGTGTAGAGAGAAGGGGGCGTCCCTTAGATCGGCATGACCTTGTGAAGCCCCTCCTCTCCAGATCCCAGGTTCCTTTTCT
GGAACAGTGATGATTGCTACTGTCTTGTAAGCATCTCACCCATGTGGCAACATGCTGTTTCCTGTGACTTTGAATCCTCCTAATCAGCCA
GCATCATGTAGGTCCTTGTCACCAGTTTTCCTGGTGGGGAAATTTAGGCTCGGGGAAAAGTGTTACATAGCAAGGCCACACATCTGTGGC
TAGGAGTCATTTGATTGCTAGGAGTAGGACCAGTGACCAGATTTAGCTTAAGGAAGATTTATTCCAGGGACCTGATCACAGAAAGCAGGG
CCCTGCAGCAGATGGGAACCAGGAAGCCATCAGGGTCTCATTCTTCACACTTCTGCATTTGTCTTGTTTCCTGCCTCTGGCTTTCTCTCC
CTGCTTTCACTTGGCCCGGCACTAGCTCTGTGGCCCCTACTTTACATTACTTCTTTGTCCAGAGCTCTCAGCATATGAGTCCAGGTCTTC

>102024_102024_8_ZNF415-SMG9_ZNF415_chr19_53619566_ENST00000597748_SMG9_chr19_44244370_ENST00000601170_length(amino acids)=286AA_BP=20
MPELYTEDFIQGCDVGELQEPGLPGTYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTY
VEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSSGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHL
MIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDSEVNLFLVPFMDSEAESENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ZNF415-SMG9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF415-SMG9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF415-SMG9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource