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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF420-DPF1 (FusionGDB2 ID:102043)

Fusion Gene Summary for ZNF420-DPF1

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF420-DPF1
Fusion gene ID: 102043
HgeneTgene
Gene symbol

ZNF420

DPF1

Gene ID

147923

8193

Gene namezinc finger protein 420double PHD fingers 1
SynonymsAPAKBAF45b|NEUD4|neuro-d4
Cytomap

19q13.12

19q13.2

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 420ATM and p53-associated KZNF proteinzinc finger protein neuro-d4BRG1-associated factor 45BD4, zinc and double PHD fingers family 1neuro-d4 homolog
Modification date2020031320200313
UniProtAcc.

Q92782

Ensembl transtripts involved in fusion geneENST00000304239, ENST00000337995, 
ENST00000586540, 		ENST00000355526, 
ENST00000412732, ENST00000414789, 
ENST00000416611, ENST00000420980, 
ENST00000456296, 
Fusion gene scores* DoF score8 X 6 X 7=3369 X 4 X 7=252
# samples 1010
** MAII scorelog2(10/336*10)=-1.74846123300404
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/252*10)=-1.33342373372519
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF420 [Title/Abstract] AND DPF1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF420(37582023)-DPF1(38704396), # samples:5
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ZNF420 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DPF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-XP-A8T6-01AZNF420chr19

37582023

-DPF1chr19

38704396

-
ChimerDB4ESCATCGA-XP-A8T6-01AZNF420chr19

37582023

+DPF1chr19

38704396

-
ChimerDB4ESCATCGA-XP-A8T6ZNF420chr19

37582023

+DPF1chr19

38704396

-
ChimerDB4ESCATCGA-XP-A8T6ZNF420chr19

37587017

+DPF1chr19

38704396

-


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Fusion Gene ORF analysis for ZNF420-DPF1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000304239ENST00000355526ZNF420chr19

37582023

+DPF1chr19

38704396

-
In-frameENST00000304239ENST00000412732ZNF420chr19

37582023

+DPF1chr19

38704396

-
In-frameENST00000304239ENST00000414789ZNF420chr19

37582023

+DPF1chr19

38704396

-
In-frameENST00000304239ENST00000416611ZNF420chr19

37582023

+DPF1chr19

38704396

-
In-frameENST00000304239ENST00000420980ZNF420chr19

37582023

+DPF1chr19

38704396

-
In-frameENST00000304239ENST00000456296ZNF420chr19

37582023

+DPF1chr19

38704396

-
In-frameENST00000337995ENST00000355526ZNF420chr19

37582023

+DPF1chr19

38704396

-
In-frameENST00000337995ENST00000412732ZNF420chr19

37582023

+DPF1chr19

38704396

-
In-frameENST00000337995ENST00000414789ZNF420chr19

37582023

+DPF1chr19

38704396

-
In-frameENST00000337995ENST00000416611ZNF420chr19

37582023

+DPF1chr19

38704396

-
In-frameENST00000337995ENST00000420980ZNF420chr19

37582023

+DPF1chr19

38704396

-
In-frameENST00000337995ENST00000456296ZNF420chr19

37582023

+DPF1chr19

38704396

-
intron-3CDSENST00000304239ENST00000355526ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000304239ENST00000412732ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000304239ENST00000414789ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000304239ENST00000416611ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000304239ENST00000420980ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000304239ENST00000456296ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000337995ENST00000355526ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000337995ENST00000412732ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000337995ENST00000414789ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000337995ENST00000416611ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000337995ENST00000420980ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000337995ENST00000456296ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000355526ZNF420chr19

37582023

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000355526ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000412732ZNF420chr19

37582023

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000412732ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000414789ZNF420chr19

37582023

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000414789ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000416611ZNF420chr19

37582023

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000416611ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000420980ZNF420chr19

37582023

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000420980ZNF420chr19

37587017

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000456296ZNF420chr19

37582023

+DPF1chr19

38704396

-
intron-3CDSENST00000586540ENST00000456296ZNF420chr19

37587017

+DPF1chr19

38704396

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000304239ZNF420chr1937582023+ENST00000420980DPF1chr1938704396-17493961604684306
ENST00000304239ZNF420chr1937582023+ENST00000412732DPF1chr1938704396-17163961574654306
ENST00000304239ZNF420chr1937582023+ENST00000416611DPF1chr1938704396-17123961604684306
ENST00000304239ZNF420chr1937582023+ENST00000414789DPF1chr1938704396-10233965321020163
ENST00000304239ZNF420chr1937582023+ENST00000355526DPF1chr1938704396-10223965321020163
ENST00000304239ZNF420chr1937582023+ENST00000456296DPF1chr1938704396-970396532969146
ENST00000337995ZNF420chr1937582023+ENST00000420980DPF1chr1938704396-17043511559639306
ENST00000337995ZNF420chr1937582023+ENST00000412732DPF1chr1938704396-16713511529609306
ENST00000337995ZNF420chr1937582023+ENST00000416611DPF1chr1938704396-16673511559639306
ENST00000337995ZNF420chr1937582023+ENST00000414789DPF1chr1938704396-978351487975163
ENST00000337995ZNF420chr1937582023+ENST00000355526DPF1chr1938704396-977351487975163
ENST00000337995ZNF420chr1937582023+ENST00000456296DPF1chr1938704396-925351487924146

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000304239ENST00000420980ZNF420chr1937582023+DPF1chr1938704396-0.287919640.7120803
ENST00000304239ENST00000412732ZNF420chr1937582023+DPF1chr1938704396-0.158099430.8419006
ENST00000304239ENST00000416611ZNF420chr1937582023+DPF1chr1938704396-0.25623890.74376106
ENST00000304239ENST00000414789ZNF420chr1937582023+DPF1chr1938704396-0.0686328040.93136716
ENST00000304239ENST00000355526ZNF420chr1937582023+DPF1chr1938704396-0.067539290.9324607
ENST00000304239ENST00000456296ZNF420chr1937582023+DPF1chr1938704396-0.0601324770.9398675
ENST00000337995ENST00000420980ZNF420chr1937582023+DPF1chr1938704396-0.277048020.72295195
ENST00000337995ENST00000412732ZNF420chr1937582023+DPF1chr1938704396-0.093641450.9063586
ENST00000337995ENST00000416611ZNF420chr1937582023+DPF1chr1938704396-0.24092980.7590702
ENST00000337995ENST00000414789ZNF420chr1937582023+DPF1chr1938704396-0.063183570.9368164
ENST00000337995ENST00000355526ZNF420chr1937582023+DPF1chr1938704396-0.0619735870.9380264
ENST00000337995ENST00000456296ZNF420chr1937582023+DPF1chr1938704396-0.048755190.9512448

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Fusion Genomic Features for ZNF420-DPF1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZNF420-DPF1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:37582023/chr19:38704396)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DPF1

Q92782

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDPF1chr19:37582023chr19:38704396ENST00000412732812254_311244333.0Zinc fingerPHD-type 1
TgeneDPF1chr19:37582023chr19:38704396ENST00000412732812308_368244333.0Zinc fingerPHD-type 2
TgeneDPF1chr19:37582023chr19:38704396ENST00000414789812254_311244333.0Zinc fingerPHD-type 1
TgeneDPF1chr19:37582023chr19:38704396ENST00000414789812308_368244333.0Zinc fingerPHD-type 2
TgeneDPF1chr19:37582023chr19:38704396ENST00000420980711308_368282381.0Zinc fingerPHD-type 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+456_8645689.0DomainKRAB
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45139_16145689.0Zinc fingerC2H2-type 1
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45167_18945689.0Zinc fingerC2H2-type 2
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45195_21745689.0Zinc fingerC2H2-type 3
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45223_24545689.0Zinc fingerC2H2-type 4
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45251_27345689.0Zinc fingerC2H2-type 5
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45279_30145689.0Zinc fingerC2H2-type 6
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45307_32945689.0Zinc fingerC2H2-type 7
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45335_35745689.0Zinc fingerC2H2-type 8
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45363_38545689.0Zinc fingerC2H2-type 9
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45391_41345689.0Zinc fingerC2H2-type 10
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45419_44145689.0Zinc fingerC2H2-type 11
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45447_46945689.0Zinc fingerC2H2-type 12
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45475_49745689.0Zinc fingerC2H2-type 13
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45503_52545689.0Zinc fingerC2H2-type 14
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45531_55345689.0Zinc fingerC2H2-type 15
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45559_58145689.0Zinc fingerC2H2-type 16
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45587_60945689.0Zinc fingerC2H2-type 17
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45615_63745689.0Zinc fingerC2H2-type 18
HgeneZNF420chr19:37582023chr19:38704396ENST00000337995+45643_66545689.0Zinc fingerC2H2-type 19
TgeneDPF1chr19:37582023chr19:38704396ENST00000355526812254_311326415.0Zinc fingerPHD-type 1
TgeneDPF1chr19:37582023chr19:38704396ENST00000355526812308_368326415.0Zinc fingerPHD-type 2
TgeneDPF1chr19:37582023chr19:38704396ENST00000420980711254_311282381.0Zinc fingerPHD-type 1


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Fusion Gene Sequence for ZNF420-DPF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102043_102043_1_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000355526_length(transcript)=1022nt_BP=396nt
GATTTGGAGGCCTCGCGTGGGGAGAGGGCCGCGTCTGTGGAGGAGCTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTG
GAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAAGAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAG
CTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAGAAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGA
AATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAGAGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATG
TGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCTCGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCT
ACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAACCTCCGAGAACGACGACCAGCTGCTGTTTTGTGATGACTGCGATC
GGGGTTACCACATGTACTGCCTGAGTCCCCCCATGGCGGAGCCCCCGGAAGGGAGCTGGAGCTGTCACCTCTGTCTCCGGCACCTGAAGG
AAAAGGCTTCTGCTTACATCACCCTCACCTAGGCCGGCTCGGCTCGCCGCGACTCTGGGGTGGTGCTCGCCTACCTGCCTCTCCGAGCTC
CTCAATTCTCCCCCACCCTGAACATCCCGCAGGGGGAGGGGGAGAGGGGGAAGCCGAGAGGGGGCTGGGCCACCCCCTCCCCTCTGTGCA
AGTGGAATGTCTGCCCTGTGGGTGGGTGGGCCCGGCCAGGGCCTCTCCCTCCCTCCCTCCCTCTCTGTCCCTTGGCAAATGGACACCAGG
GGCTTCTCCCCTCAAAGCCATACCCCGCCTCTGGGCGGGCATGGGGGGTGGTGGGTGCCAGCCAGGGGCATGGACAGAGCCTTTTTCTAA

>102043_102043_1_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000355526_length(amino acids)=163AA_BP=
MRSGLPHVLPESPHGGAPGRELELSPLSPAPEGKGFCLHHPHLGRLGSPRLWGGARLPASPSSSILPHPEHPAGGGGEGEAERGLGHPLP

--------------------------------------------------------------
>102043_102043_2_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000412732_length(transcript)=1716nt_BP=396nt
GATTTGGAGGCCTCGCGTGGGGAGAGGGCCGCGTCTGTGGAGGAGCTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTG
GAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAAGAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAG
CTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAGAAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGA
AATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAGAGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATG
TGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCTCGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCT
ACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAACCTCCGAGAACGACGACCAGCTGCTGTTTTGTGATGACTGCGATC
GGGGTTACCACATGTACTGCCTGAGTCCCCCCATGGCGGAGCCCCCGGAAGGGAGCTGGAGCTGTCACCTCTGTCTCCGGCACCTGAAGG
AAAAGGCTTCTGCTTACATCACCCTCACCTAGGCCGGCTCGGCTCGCCGCGACTCTGGGGTGGTGCTCGCCTACCTGCCTCTCCGAGCTC
CTCAATTCTCCCCCACCCTGAACATCCCGCAGGGGGAGGGGGAGAGGGGGAAGCCGAGAGGGGGCTGGGCCACCCCCTCCCCTCTGTGCA
AGTGGAATGTCTGCCCTGTGGGTGGGTGGGCCCGGCCAGGGCCTCTCCCTCCCTCCCTCCCTCTCTGTCCCTTGGCAAATGGACACCAGG
GGCTTCTCCCCTCAAAGCCATACCCCGCCTCTGGGCGGGCATGGGGGGTGGTGGGTGCCAGCCAGGGGCATGGACAGAGCCTTTTTCTAA
AGAAAAAGACAAAAAGTTAAAAAAAAAAAAAAGAAGAAAAGAAAAGAAGTTAATATATACAAAGAGTCCTCCAAGGCCTGGCTGGGTGGA
GGGGCGCTGCTGAGAGTGTCCACCGGGCACCCGCCTCTGCCGGCCCCCCGCCGGGCGCCCCAACCCCAATTTCTGGAGCTGCAGCCGTCC
CGCGCCCCACCCAAGGTGGGCGCCTTCCCCTCTTGTGCCCAGGGCGGTGGGCGTGGTGTCCACCCGCCCCTCCTGGTGCCCACGGTGGAT
ACTGCATGATGTGAACCTTGGTTTTGAACTCTGTTCCTGCCCCTCCCCGACCGCCCCAGCCTGTGCCCGCCCCGTGCCTGCCGTGGCTGG
TGGGTGGCGGTGGTGGGGCCGGGTGGGCCCCCGCCCAGCGCCTGCTGGAATGAGAAGCACAGACTCCGCCACGGACTCCTTTTCTCTCCC
TCCTCCCGCCCCGCCAGGCCTGGCGGCCCCCGCCCCCCTCGCTGGCCATTTTGGGGGAGTGAGGGGGCGTGGTTGTTTCTTGTGGTTGTG
TGTGTTTGTTGTTCGGGTTTTAAAAAAGGGAAACTGAGACTGCAGGTGGGGGAGGTGGTGGGTTTTGGGGGGATGTCCCCTAATCCAGGA
GTGCCCCCTCACTTGTCACCGAGTCTCCTCTATTGCCTGCCTCTGCTGTGAATTAACTTGTTCTGTGTATTAAACTGGGCCTGACCCCTC

>102043_102043_2_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000412732_length(amino acids)=306AA_BP=
MQSQFPFFKTRTTNTHNHKKQPRPLTPPKWPARGAGAARPGGAGGGREKESVAESVLLIPAGAGRGPTRPHHRHPPATAGTGRAQAGAVG
EGQEQSSKPRFTSCSIHRGHQEGRVDTTPTALGTRGEGAHLGWGAGRLQLQKLGLGRPAGGRQRRVPGGHSQQRPSTQPGLGGLFVYINF
FSFLLFFFFNFLSFSLEKGSVHAPGWHPPPPMPAQRRGMALRGEAPGVHLPRDREGGREGEALAGPTHPQGRHSTCTEGRGWPSPLSASP

--------------------------------------------------------------
>102043_102043_3_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000414789_length(transcript)=1023nt_BP=396nt
GATTTGGAGGCCTCGCGTGGGGAGAGGGCCGCGTCTGTGGAGGAGCTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTG
GAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAAGAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAG
CTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAGAAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGA
AATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAGAGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATG
TGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCTCGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCT
ACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAACCTCCGAGAACGACGACCAGCTGCTGTTTTGTGATGACTGCGATC
GGGGTTACCACATGTACTGCCTGAGTCCCCCCATGGCGGAGCCCCCGGAAGGGAGCTGGAGCTGTCACCTCTGTCTCCGGCACCTGAAGG
AAAAGGCTTCTGCTTACATCACCCTCACCTAGGCCGGCTCGGCTCGCCGCGACTCTGGGGTGGTGCTCGCCTACCTGCCTCTCCGAGCTC
CTCAATTCTCCCCCACCCTGAACATCCCGCAGGGGGAGGGGGAGAGGGGGAAGCCGAGAGGGGGCTGGGCCACCCCCTCCCCTCTGTGCA
AGTGGAATGTCTGCCCTGTGGGTGGGTGGGCCCGGCCAGGGCCTCTCCCTCCCTCCCTCCCTCTCTGTCCCTTGGCAAATGGACACCAGG
GGCTTCTCCCCTCAAAGCCATACCCCGCCTCTGGGCGGGCATGGGGGGTGGTGGGTGCCAGCCAGGGGCATGGACAGAGCCTTTTTCTAA

>102043_102043_3_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000414789_length(amino acids)=163AA_BP=
MRSGLPHVLPESPHGGAPGRELELSPLSPAPEGKGFCLHHPHLGRLGSPRLWGGARLPASPSSSILPHPEHPAGGGGEGEAERGLGHPLP

--------------------------------------------------------------
>102043_102043_4_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000416611_length(transcript)=1712nt_BP=396nt
GATTTGGAGGCCTCGCGTGGGGAGAGGGCCGCGTCTGTGGAGGAGCTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTG
GAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAAGAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAG
CTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAGAAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGA
AATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAGAGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATG
TGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCTCGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCT
ACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAACCTCCGAGAACGACGGTGCCAGCTGGGCGGGTCTCACCCCCCAGG
ACCAGCTGCTGTTTTGTGATGACTGCGATCGGGGTTACCACATGTACTGCCTGAGTCCCCCCATGGCGGAGCCCCCGGAAGGGAGCTGGA
GCTGTCACCTCTGTCTCCGGCACCTGAAGGAAAAGGCTTCTGCTTACATCACCCTCACCTAGGCCGGCTCGGCTCGCCGCGACTCTGGGG
TGGTGCTCGCCTACCTGCCTCTCCGAGCTCCTCAATTCTCCCCCACCCTGAACATCCCGCAGGGGGAGGGGGAGAGGGGGAAGCCGAGAG
GGGGCTGGGCCACCCCCTCCCCTCTGTGCAAGTGGAATGTCTGCCCTGTGGGTGGGTGGGCCCGGCCAGGGCCTCTCCCTCCCTCCCTCC
CTCTCTGTCCCTTGGCAAATGGACACCAGGGGCTTCTCCCCTCAAAGCCATACCCCGCCTCTGGGCGGGCATGGGGGGTGGTGGGTGCCA
GCCAGGGGCATGGACAGAGCCTTTTTCTAAAGAAAAAGACAAAAAGTTAAAAAAAAAAAAAAGAAGAAAAGAAAAGAAGTTAATATATAC
AAAGAGTCCTCCAAGGCCTGGCTGGGTGGAGGGGCGCTGCTGAGAGTGTCCACCGGGCACCCGCCTCTGCCGGCCCCCCGCCGGGCGCCC
CAACCCCAATTTCTGGAGCTGCAGCCGTCCCGCGCCCCACCCAAGGTGGGCGCCTTCCCCTCTTGTGCCCAGGGCGGTGGGCGTGGTGTC
CACCCGCCCCTCCTGGTGCCCACGGTGGATACTGCATGATGTGAACCTTGGTTTTGAACTCTGTTCCTGCCCCTCCCCGACCGCCCCAGC
CTGTGCCCGCCCCGTGCCTGCCGTGGCTGGTGGGTGGCGGTGGTGGGGCCGGGTGGGCCCCCGCCCAGCGCCTGCTGGAATGAGAAGCAC
AGACTCCGCCACGGACTCCTTTTCTCTCCCTCCTCCCGCCCCGCCAGGCCTGGCGGCCCCCGCCCCCCTCGCTGGCCATTTTGGGGGAGT
GAGGGGGCGTGGTTGTTTCTTGTGGTTGTGTGTGTTTGTTGTTCGGGTTTTAAAAAAGGGAAACTGAGACTGCAGGTGGGGGAGGTGGTG
GGTTTTGGGGGGATGTCCCCTAATCCAGGAGTGCCCCCTCACTTGTCACCGAGTCTCCTCTATTGCCTGCCTCTGCTGTGAATTAACTTG

>102043_102043_4_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000416611_length(amino acids)=306AA_BP=
MQSQFPFFKTRTTNTHNHKKQPRPLTPPKWPARGAGAARPGGAGGGREKESVAESVLLIPAGAGRGPTRPHHRHPPATAGTGRAQAGAVG
EGQEQSSKPRFTSCSIHRGHQEGRVDTTPTALGTRGEGAHLGWGAGRLQLQKLGLGRPAGGRQRRVPGGHSQQRPSTQPGLGGLFVYINF
FSFLLFFFFNFLSFSLEKGSVHAPGWHPPPPMPAQRRGMALRGEAPGVHLPRDREGGREGEALAGPTHPQGRHSTCTEGRGWPSPLSASP

--------------------------------------------------------------
>102043_102043_5_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000420980_length(transcript)=1749nt_BP=396nt
GATTTGGAGGCCTCGCGTGGGGAGAGGGCCGCGTCTGTGGAGGAGCTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTG
GAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAAGAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAG
CTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAGAAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGA
AATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAGAGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATG
TGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCTCGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCT
ACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAACCTCCGAGAACGACGGTGCCAGCTGGGCGGGTCTCACCCCCCAGG
ACCAGCTGCTGTTTTGTGATGACTGCGATCGGGGTTACCACATGTACTGCCTGAGTCCCCCCATGGCGGAGCCCCCGGAAGGGAGCTGGA
GCTGTCACCTCTGTCTCCGGCACCTGAAGGAAAAGGCTTCTGCTTACATCACCCTCACCTAGGCCGGCTCGGCTCGCCGCGACTCTGGGG
TGGTGCTCGCCTACCTGCCTCTCCGAGCTCCTCAATTCTCCCCCACCCTGAACATCCCGCAGGGGGAGGGGGAGAGGGGGAAGCCGAGAG
GGGGCTGGGCCACCCCCTCCCCTCTGTGCAAGTGGAATGTCTGCCCTGTGGGTGGGTGGGCCCGGCCAGGGCCTCTCCCTCCCTCCCTCC
CTCTCTGTCCCTTGGCAAATGGACACCAGGGGCTTCTCCCCTCAAAGCCATACCCCGCCTCTGGGCGGGCATGGGGGGTGGTGGGTGCCA
GCCAGGGGCATGGACAGAGCCTTTTTCTAAAGAAAAAGACAAAAAGTTAAAAAAAAAAAAAAGAAGAAAAGAAAAGAAGTTAATATATAC
AAAGAGTCCTCCAAGGCCTGGCTGGGTGGAGGGGCGCTGCTGAGAGTGTCCACCGGGCACCCGCCTCTGCCGGCCCCCCGCCGGGCGCCC
CAACCCCAATTTCTGGAGCTGCAGCCGTCCCGCGCCCCACCCAAGGTGGGCGCCTTCCCCTCTTGTGCCCAGGGCGGTGGGCGTGGTGTC
CACCCGCCCCTCCTGGTGCCCACGGTGGATACTGCATGATGTGAACCTTGGTTTTGAACTCTGTTCCTGCCCCTCCCCGACCGCCCCAGC
CTGTGCCCGCCCCGTGCCTGCCGTGGCTGGTGGGTGGCGGTGGTGGGGCCGGGTGGGCCCCCGCCCAGCGCCTGCTGGAATGAGAAGCAC
AGACTCCGCCACGGACTCCTTTTCTCTCCCTCCTCCCGCCCCGCCAGGCCTGGCGGCCCCCGCCCCCCTCGCTGGCCATTTTGGGGGAGT
GAGGGGGCGTGGTTGTTTCTTGTGGTTGTGTGTGTTTGTTGTTCGGGTTTTAAAAAAGGGAAACTGAGACTGCAGGTGGGGGAGGTGGTG
GGTTTTGGGGGGATGTCCCCTAATCCAGGAGTGCCCCCTCACTTGTCACCGAGTCTCCTCTATTGCCTGCCTCTGCTGTGAATTAACTTG

>102043_102043_5_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000420980_length(amino acids)=306AA_BP=
MQSQFPFFKTRTTNTHNHKKQPRPLTPPKWPARGAGAARPGGAGGGREKESVAESVLLIPAGAGRGPTRPHHRHPPATAGTGRAQAGAVG
EGQEQSSKPRFTSCSIHRGHQEGRVDTTPTALGTRGEGAHLGWGAGRLQLQKLGLGRPAGGRQRRVPGGHSQQRPSTQPGLGGLFVYINF
FSFLLFFFFNFLSFSLEKGSVHAPGWHPPPPMPAQRRGMALRGEAPGVHLPRDREGGREGEALAGPTHPQGRHSTCTEGRGWPSPLSASP

--------------------------------------------------------------
>102043_102043_6_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000456296_length(transcript)=970nt_BP=396nt
GATTTGGAGGCCTCGCGTGGGGAGAGGGCCGCGTCTGTGGAGGAGCTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTG
GAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAAGAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAG
CTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAGAAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGA
AATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAGAGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATG
TGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCTCGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCT
ACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAACCTCCGAGAACGACGACCAGCTGCTGTTTTGTGATGACTGCGATC
GGGGTTACCACATGTACTGCCTGAGTCCCCCCATGGCGGAGCCCCCGGAAGGGAGCTGGAGCTGTCACCTCTGTCTCCGGCACCTGAAGG
AAAAGGCTTCTGCTTACATCACCCTCACCTAGGCCGGCTCGGCTCGCCGCGACTCTGGGGTGGTGCTCGCCTACCTGCCTCTCCGAGCTC
CTCAATTCTCCCCCACCCTGAACATCCCGCAGGGGGAGGGGGAGAGGGGGAAGCCGAGAGGGGGCTGGGCCACCCCCTCCCCTCTGTGCA
AGTGGAATGTCTGCCCTGTGGGTGGGTGGGCCCGGCCAGGGCCTCTCCCTCCCTCCCTCCCTCTCTGTCCCTTGGCAAATGGACACCAGG

>102043_102043_6_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000304239_DPF1_chr19_38704396_ENST00000456296_length(amino acids)=146AA_BP=
MRSGLPHVLPESPHGGAPGRELELSPLSPAPEGKGFCLHHPHLGRLGSPRLWGGARLPASPSSSILPHPEHPAGGGGEGEAERGLGHPLP

--------------------------------------------------------------
>102043_102043_7_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000355526_length(transcript)=977nt_BP=351nt
CTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTGGAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAA
GAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAGCTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAG
AAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGAAATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAG
AGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATGTGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCT
CGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCTACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAA
CCTCCGAGAACGACGACCAGCTGCTGTTTTGTGATGACTGCGATCGGGGTTACCACATGTACTGCCTGAGTCCCCCCATGGCGGAGCCCC
CGGAAGGGAGCTGGAGCTGTCACCTCTGTCTCCGGCACCTGAAGGAAAAGGCTTCTGCTTACATCACCCTCACCTAGGCCGGCTCGGCTC
GCCGCGACTCTGGGGTGGTGCTCGCCTACCTGCCTCTCCGAGCTCCTCAATTCTCCCCCACCCTGAACATCCCGCAGGGGGAGGGGGAGA
GGGGGAAGCCGAGAGGGGGCTGGGCCACCCCCTCCCCTCTGTGCAAGTGGAATGTCTGCCCTGTGGGTGGGTGGGCCCGGCCAGGGCCTC
TCCCTCCCTCCCTCCCTCTCTGTCCCTTGGCAAATGGACACCAGGGGCTTCTCCCCTCAAAGCCATACCCCGCCTCTGGGCGGGCATGGG

>102043_102043_7_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000355526_length(amino acids)=163AA_BP=
MRSGLPHVLPESPHGGAPGRELELSPLSPAPEGKGFCLHHPHLGRLGSPRLWGGARLPASPSSSILPHPEHPAGGGGEGEAERGLGHPLP

--------------------------------------------------------------
>102043_102043_8_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000412732_length(transcript)=1671nt_BP=351nt
CTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTGGAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAA
GAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAGCTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAG
AAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGAAATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAG
AGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATGTGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCT
CGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCTACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAA
CCTCCGAGAACGACGACCAGCTGCTGTTTTGTGATGACTGCGATCGGGGTTACCACATGTACTGCCTGAGTCCCCCCATGGCGGAGCCCC
CGGAAGGGAGCTGGAGCTGTCACCTCTGTCTCCGGCACCTGAAGGAAAAGGCTTCTGCTTACATCACCCTCACCTAGGCCGGCTCGGCTC
GCCGCGACTCTGGGGTGGTGCTCGCCTACCTGCCTCTCCGAGCTCCTCAATTCTCCCCCACCCTGAACATCCCGCAGGGGGAGGGGGAGA
GGGGGAAGCCGAGAGGGGGCTGGGCCACCCCCTCCCCTCTGTGCAAGTGGAATGTCTGCCCTGTGGGTGGGTGGGCCCGGCCAGGGCCTC
TCCCTCCCTCCCTCCCTCTCTGTCCCTTGGCAAATGGACACCAGGGGCTTCTCCCCTCAAAGCCATACCCCGCCTCTGGGCGGGCATGGG
GGGTGGTGGGTGCCAGCCAGGGGCATGGACAGAGCCTTTTTCTAAAGAAAAAGACAAAAAGTTAAAAAAAAAAAAAAGAAGAAAAGAAAA
GAAGTTAATATATACAAAGAGTCCTCCAAGGCCTGGCTGGGTGGAGGGGCGCTGCTGAGAGTGTCCACCGGGCACCCGCCTCTGCCGGCC
CCCCGCCGGGCGCCCCAACCCCAATTTCTGGAGCTGCAGCCGTCCCGCGCCCCACCCAAGGTGGGCGCCTTCCCCTCTTGTGCCCAGGGC
GGTGGGCGTGGTGTCCACCCGCCCCTCCTGGTGCCCACGGTGGATACTGCATGATGTGAACCTTGGTTTTGAACTCTGTTCCTGCCCCTC
CCCGACCGCCCCAGCCTGTGCCCGCCCCGTGCCTGCCGTGGCTGGTGGGTGGCGGTGGTGGGGCCGGGTGGGCCCCCGCCCAGCGCCTGC
TGGAATGAGAAGCACAGACTCCGCCACGGACTCCTTTTCTCTCCCTCCTCCCGCCCCGCCAGGCCTGGCGGCCCCCGCCCCCCTCGCTGG
CCATTTTGGGGGAGTGAGGGGGCGTGGTTGTTTCTTGTGGTTGTGTGTGTTTGTTGTTCGGGTTTTAAAAAAGGGAAACTGAGACTGCAG
GTGGGGGAGGTGGTGGGTTTTGGGGGGATGTCCCCTAATCCAGGAGTGCCCCCTCACTTGTCACCGAGTCTCCTCTATTGCCTGCCTCTG

>102043_102043_8_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000412732_length(amino acids)=306AA_BP=
MQSQFPFFKTRTTNTHNHKKQPRPLTPPKWPARGAGAARPGGAGGGREKESVAESVLLIPAGAGRGPTRPHHRHPPATAGTGRAQAGAVG
EGQEQSSKPRFTSCSIHRGHQEGRVDTTPTALGTRGEGAHLGWGAGRLQLQKLGLGRPAGGRQRRVPGGHSQQRPSTQPGLGGLFVYINF
FSFLLFFFFNFLSFSLEKGSVHAPGWHPPPPMPAQRRGMALRGEAPGVHLPRDREGGREGEALAGPTHPQGRHSTCTEGRGWPSPLSASP

--------------------------------------------------------------
>102043_102043_9_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000414789_length(transcript)=978nt_BP=351nt
CTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTGGAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAA
GAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAGCTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAG
AAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGAAATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAG
AGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATGTGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCT
CGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCTACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAA
CCTCCGAGAACGACGACCAGCTGCTGTTTTGTGATGACTGCGATCGGGGTTACCACATGTACTGCCTGAGTCCCCCCATGGCGGAGCCCC
CGGAAGGGAGCTGGAGCTGTCACCTCTGTCTCCGGCACCTGAAGGAAAAGGCTTCTGCTTACATCACCCTCACCTAGGCCGGCTCGGCTC
GCCGCGACTCTGGGGTGGTGCTCGCCTACCTGCCTCTCCGAGCTCCTCAATTCTCCCCCACCCTGAACATCCCGCAGGGGGAGGGGGAGA
GGGGGAAGCCGAGAGGGGGCTGGGCCACCCCCTCCCCTCTGTGCAAGTGGAATGTCTGCCCTGTGGGTGGGTGGGCCCGGCCAGGGCCTC
TCCCTCCCTCCCTCCCTCTCTGTCCCTTGGCAAATGGACACCAGGGGCTTCTCCCCTCAAAGCCATACCCCGCCTCTGGGCGGGCATGGG

>102043_102043_9_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000414789_length(amino acids)=163AA_BP=
MRSGLPHVLPESPHGGAPGRELELSPLSPAPEGKGFCLHHPHLGRLGSPRLWGGARLPASPSSSILPHPEHPAGGGGEGEAERGLGHPLP

--------------------------------------------------------------
>102043_102043_10_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000416611_length(transcript)=1667nt_BP=351nt
CTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTGGAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAA
GAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAGCTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAG
AAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGAAATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAG
AGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATGTGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCT
CGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCTACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAA
CCTCCGAGAACGACGGTGCCAGCTGGGCGGGTCTCACCCCCCAGGACCAGCTGCTGTTTTGTGATGACTGCGATCGGGGTTACCACATGT
ACTGCCTGAGTCCCCCCATGGCGGAGCCCCCGGAAGGGAGCTGGAGCTGTCACCTCTGTCTCCGGCACCTGAAGGAAAAGGCTTCTGCTT
ACATCACCCTCACCTAGGCCGGCTCGGCTCGCCGCGACTCTGGGGTGGTGCTCGCCTACCTGCCTCTCCGAGCTCCTCAATTCTCCCCCA
CCCTGAACATCCCGCAGGGGGAGGGGGAGAGGGGGAAGCCGAGAGGGGGCTGGGCCACCCCCTCCCCTCTGTGCAAGTGGAATGTCTGCC
CTGTGGGTGGGTGGGCCCGGCCAGGGCCTCTCCCTCCCTCCCTCCCTCTCTGTCCCTTGGCAAATGGACACCAGGGGCTTCTCCCCTCAA
AGCCATACCCCGCCTCTGGGCGGGCATGGGGGGTGGTGGGTGCCAGCCAGGGGCATGGACAGAGCCTTTTTCTAAAGAAAAAGACAAAAA
GTTAAAAAAAAAAAAAAGAAGAAAAGAAAAGAAGTTAATATATACAAAGAGTCCTCCAAGGCCTGGCTGGGTGGAGGGGCGCTGCTGAGA
GTGTCCACCGGGCACCCGCCTCTGCCGGCCCCCCGCCGGGCGCCCCAACCCCAATTTCTGGAGCTGCAGCCGTCCCGCGCCCCACCCAAG
GTGGGCGCCTTCCCCTCTTGTGCCCAGGGCGGTGGGCGTGGTGTCCACCCGCCCCTCCTGGTGCCCACGGTGGATACTGCATGATGTGAA
CCTTGGTTTTGAACTCTGTTCCTGCCCCTCCCCGACCGCCCCAGCCTGTGCCCGCCCCGTGCCTGCCGTGGCTGGTGGGTGGCGGTGGTG
GGGCCGGGTGGGCCCCCGCCCAGCGCCTGCTGGAATGAGAAGCACAGACTCCGCCACGGACTCCTTTTCTCTCCCTCCTCCCGCCCCGCC
AGGCCTGGCGGCCCCCGCCCCCCTCGCTGGCCATTTTGGGGGAGTGAGGGGGCGTGGTTGTTTCTTGTGGTTGTGTGTGTTTGTTGTTCG
GGTTTTAAAAAAGGGAAACTGAGACTGCAGGTGGGGGAGGTGGTGGGTTTTGGGGGGATGTCCCCTAATCCAGGAGTGCCCCCTCACTTG

>102043_102043_10_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000416611_length(amino acids)=306AA_BP=
MQSQFPFFKTRTTNTHNHKKQPRPLTPPKWPARGAGAARPGGAGGGREKESVAESVLLIPAGAGRGPTRPHHRHPPATAGTGRAQAGAVG
EGQEQSSKPRFTSCSIHRGHQEGRVDTTPTALGTRGEGAHLGWGAGRLQLQKLGLGRPAGGRQRRVPGGHSQQRPSTQPGLGGLFVYINF
FSFLLFFFFNFLSFSLEKGSVHAPGWHPPPPMPAQRRGMALRGEAPGVHLPRDREGGREGEALAGPTHPQGRHSTCTEGRGWPSPLSASP

--------------------------------------------------------------
>102043_102043_11_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000420980_length(transcript)=1704nt_BP=351nt
CTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTGGAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAA
GAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAGCTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAG
AAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGAAATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAG
AGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATGTGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCT
CGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCTACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAA
CCTCCGAGAACGACGGTGCCAGCTGGGCGGGTCTCACCCCCCAGGACCAGCTGCTGTTTTGTGATGACTGCGATCGGGGTTACCACATGT
ACTGCCTGAGTCCCCCCATGGCGGAGCCCCCGGAAGGGAGCTGGAGCTGTCACCTCTGTCTCCGGCACCTGAAGGAAAAGGCTTCTGCTT
ACATCACCCTCACCTAGGCCGGCTCGGCTCGCCGCGACTCTGGGGTGGTGCTCGCCTACCTGCCTCTCCGAGCTCCTCAATTCTCCCCCA
CCCTGAACATCCCGCAGGGGGAGGGGGAGAGGGGGAAGCCGAGAGGGGGCTGGGCCACCCCCTCCCCTCTGTGCAAGTGGAATGTCTGCC
CTGTGGGTGGGTGGGCCCGGCCAGGGCCTCTCCCTCCCTCCCTCCCTCTCTGTCCCTTGGCAAATGGACACCAGGGGCTTCTCCCCTCAA
AGCCATACCCCGCCTCTGGGCGGGCATGGGGGGTGGTGGGTGCCAGCCAGGGGCATGGACAGAGCCTTTTTCTAAAGAAAAAGACAAAAA
GTTAAAAAAAAAAAAAAGAAGAAAAGAAAAGAAGTTAATATATACAAAGAGTCCTCCAAGGCCTGGCTGGGTGGAGGGGCGCTGCTGAGA
GTGTCCACCGGGCACCCGCCTCTGCCGGCCCCCCGCCGGGCGCCCCAACCCCAATTTCTGGAGCTGCAGCCGTCCCGCGCCCCACCCAAG
GTGGGCGCCTTCCCCTCTTGTGCCCAGGGCGGTGGGCGTGGTGTCCACCCGCCCCTCCTGGTGCCCACGGTGGATACTGCATGATGTGAA
CCTTGGTTTTGAACTCTGTTCCTGCCCCTCCCCGACCGCCCCAGCCTGTGCCCGCCCCGTGCCTGCCGTGGCTGGTGGGTGGCGGTGGTG
GGGCCGGGTGGGCCCCCGCCCAGCGCCTGCTGGAATGAGAAGCACAGACTCCGCCACGGACTCCTTTTCTCTCCCTCCTCCCGCCCCGCC
AGGCCTGGCGGCCCCCGCCCCCCTCGCTGGCCATTTTGGGGGAGTGAGGGGGCGTGGTTGTTTCTTGTGGTTGTGTGTGTTTGTTGTTCG
GGTTTTAAAAAAGGGAAACTGAGACTGCAGGTGGGGGAGGTGGTGGGTTTTGGGGGGATGTCCCCTAATCCAGGAGTGCCCCCTCACTTG

>102043_102043_11_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000420980_length(amino acids)=306AA_BP=
MQSQFPFFKTRTTNTHNHKKQPRPLTPPKWPARGAGAARPGGAGGGREKESVAESVLLIPAGAGRGPTRPHHRHPPATAGTGRAQAGAVG
EGQEQSSKPRFTSCSIHRGHQEGRVDTTPTALGTRGEGAHLGWGAGRLQLQKLGLGRPAGGRQRRVPGGHSQQRPSTQPGLGGLFVYINF
FSFLLFFFFNFLSFSLEKGSVHAPGWHPPPPMPAQRRGMALRGEAPGVHLPRDREGGREGEALAGPTHPQGRHSTCTEGRGWPSPLSASP

--------------------------------------------------------------
>102043_102043_12_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000456296_length(transcript)=925nt_BP=351nt
CTTGGCTCCGCACCTGCTGGGCTGGCGAACCCGAAATTGGGCTTGGAACCCGGGAGCCAGATCTTGGACCCTGAACTGCACCTCTGTCAA
GAGCCCAGAGGAGAAAGAATGGCTGTTTCAGTAGCAATGTCCAAGCTCTGCATTCTCCAGACTCTGTGCTTTCCTAAGATAGGAACCCAG
AAGAGGACTGATCATTTCTTGCAGCTCTAAAAACCATGGCTCGGAAATTAGTGATGTTCAGGGATGTTGCCATTGACTTCTCTCAGGAAG
AGTGGGAATGCCTGGACTCTGCTCAGAGAGATTTGTATAGAGATGTGATGTTGGAGAACTATAGCAACTTGGTATCACTAGGACACCCCT
CGTGTTTACAATTCACGGTGAACATGACGGCAGCCGTGCGGACCTACCGCTGGCAGTGCATCGAGTGCAAATCCTGCAGCCTGTGCGGAA
CCTCCGAGAACGACGACCAGCTGCTGTTTTGTGATGACTGCGATCGGGGTTACCACATGTACTGCCTGAGTCCCCCCATGGCGGAGCCCC
CGGAAGGGAGCTGGAGCTGTCACCTCTGTCTCCGGCACCTGAAGGAAAAGGCTTCTGCTTACATCACCCTCACCTAGGCCGGCTCGGCTC
GCCGCGACTCTGGGGTGGTGCTCGCCTACCTGCCTCTCCGAGCTCCTCAATTCTCCCCCACCCTGAACATCCCGCAGGGGGAGGGGGAGA
GGGGGAAGCCGAGAGGGGGCTGGGCCACCCCCTCCCCTCTGTGCAAGTGGAATGTCTGCCCTGTGGGTGGGTGGGCCCGGCCAGGGCCTC
TCCCTCCCTCCCTCCCTCTCTGTCCCTTGGCAAATGGACACCAGGGGCTTCTCCCCTCAAAGCCATACCCCGCCTCTGGGCGGGCATGGG

>102043_102043_12_ZNF420-DPF1_ZNF420_chr19_37582023_ENST00000337995_DPF1_chr19_38704396_ENST00000456296_length(amino acids)=146AA_BP=
MRSGLPHVLPESPHGGAPGRELELSPLSPAPEGKGFCLHHPHLGRLGSPRLWGGARLPASPSSSILPHPEHPAGGGGEGEAERGLGHPLP

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Fusion Gene PPI Analysis for ZNF420-DPF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF420-DPF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF420-DPF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource