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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BRD9-CEP72 (FusionGDB2 ID:10223)

Fusion Gene Summary for BRD9-CEP72

check button Fusion gene summary
Fusion gene informationFusion gene name: BRD9-CEP72
Fusion gene ID: 10223
HgeneTgene
Gene symbol

BRD9

CEP72

Gene ID

65980

55722

Gene namebromodomain containing 9centrosomal protein 72
SynonymsLAVS3040|PRO9856-
Cytomap

5p15.33

5p15.33

Type of geneprotein-codingprotein-coding
Descriptionbromodomain-containing protein 9rhabdomyosarcoma antigen MU-RMS-40.8sarcoma antigen NY-SAR-29centrosomal protein of 72 kDacentrosomal protein 72kDa
Modification date2020031520200327
UniProtAcc

Q9H8M2

Q9P209

Ensembl transtripts involved in fusion geneENST00000467963, ENST00000483173, 
ENST00000435709, ENST00000323510, 
ENST00000388890, ENST00000494422, 
ENST00000444221, ENST00000514507, 
ENST00000264935, 
Fusion gene scores* DoF score10 X 15 X 7=10502 X 4 X 2=16
# samples 123
** MAII scorelog2(12/1050*10)=-3.12928301694497
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/16*10)=0.906890595608518
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: BRD9 [Title/Abstract] AND CEP72 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBRD9(891269)-CEP72(647921), # samples:1
BRD9(891269)-CEP72(647919), # samples:1
BRD9(891270)-CEP72(647920), # samples:1
Anticipated loss of major functional domain due to fusion event.BRD9-CEP72 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
BRD9-CEP72 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
BRD9-CEP72 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across BRD9 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CEP72 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-90-6837-01ABRD9chr5

891269

-CEP72chr5

647921

+
ChimerDB4LUSCTCGA-90-6837-01ABRD9chr5

891270

-CEP72chr5

647920

+
ChimerDB4LUSCTCGA-90-6837BRD9chr5

891269

-CEP72chr5

647919

+


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Fusion Gene ORF analysis for BRD9-CEP72

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000467963ENST00000444221BRD9chr5

891269

-CEP72chr5

647921

+
5CDS-3UTRENST00000467963ENST00000444221BRD9chr5

891270

-CEP72chr5

647920

+
5CDS-3UTRENST00000467963ENST00000444221BRD9chr5

891269

-CEP72chr5

647919

+
5CDS-3UTRENST00000483173ENST00000444221BRD9chr5

891269

-CEP72chr5

647921

+
5CDS-3UTRENST00000483173ENST00000444221BRD9chr5

891270

-CEP72chr5

647920

+
5CDS-3UTRENST00000483173ENST00000444221BRD9chr5

891269

-CEP72chr5

647919

+
5CDS-intronENST00000467963ENST00000514507BRD9chr5

891269

-CEP72chr5

647921

+
5CDS-intronENST00000467963ENST00000514507BRD9chr5

891270

-CEP72chr5

647920

+
5CDS-intronENST00000467963ENST00000514507BRD9chr5

891269

-CEP72chr5

647919

+
5CDS-intronENST00000483173ENST00000514507BRD9chr5

891269

-CEP72chr5

647921

+
5CDS-intronENST00000483173ENST00000514507BRD9chr5

891270

-CEP72chr5

647920

+
5CDS-intronENST00000483173ENST00000514507BRD9chr5

891269

-CEP72chr5

647919

+
5UTR-3CDSENST00000435709ENST00000264935BRD9chr5

891269

-CEP72chr5

647921

+
5UTR-3CDSENST00000435709ENST00000264935BRD9chr5

891270

-CEP72chr5

647920

+
5UTR-3CDSENST00000435709ENST00000264935BRD9chr5

891269

-CEP72chr5

647919

+
5UTR-3UTRENST00000435709ENST00000444221BRD9chr5

891269

-CEP72chr5

647921

+
5UTR-3UTRENST00000435709ENST00000444221BRD9chr5

891270

-CEP72chr5

647920

+
5UTR-3UTRENST00000435709ENST00000444221BRD9chr5

891269

-CEP72chr5

647919

+
5UTR-intronENST00000435709ENST00000514507BRD9chr5

891269

-CEP72chr5

647921

+
5UTR-intronENST00000435709ENST00000514507BRD9chr5

891270

-CEP72chr5

647920

+
5UTR-intronENST00000435709ENST00000514507BRD9chr5

891269

-CEP72chr5

647919

+
Frame-shiftENST00000483173ENST00000264935BRD9chr5

891269

-CEP72chr5

647921

+
Frame-shiftENST00000483173ENST00000264935BRD9chr5

891270

-CEP72chr5

647920

+
Frame-shiftENST00000483173ENST00000264935BRD9chr5

891269

-CEP72chr5

647919

+
In-frameENST00000467963ENST00000264935BRD9chr5

891269

-CEP72chr5

647921

+
In-frameENST00000467963ENST00000264935BRD9chr5

891270

-CEP72chr5

647920

+
In-frameENST00000467963ENST00000264935BRD9chr5

891269

-CEP72chr5

647919

+
intron-3CDSENST00000323510ENST00000264935BRD9chr5

891269

-CEP72chr5

647921

+
intron-3CDSENST00000323510ENST00000264935BRD9chr5

891270

-CEP72chr5

647920

+
intron-3CDSENST00000323510ENST00000264935BRD9chr5

891269

-CEP72chr5

647919

+
intron-3CDSENST00000388890ENST00000264935BRD9chr5

891269

-CEP72chr5

647921

+
intron-3CDSENST00000388890ENST00000264935BRD9chr5

891270

-CEP72chr5

647920

+
intron-3CDSENST00000388890ENST00000264935BRD9chr5

891269

-CEP72chr5

647919

+
intron-3CDSENST00000494422ENST00000264935BRD9chr5

891269

-CEP72chr5

647921

+
intron-3CDSENST00000494422ENST00000264935BRD9chr5

891270

-CEP72chr5

647920

+
intron-3CDSENST00000494422ENST00000264935BRD9chr5

891269

-CEP72chr5

647919

+
intron-3UTRENST00000323510ENST00000444221BRD9chr5

891269

-CEP72chr5

647921

+
intron-3UTRENST00000323510ENST00000444221BRD9chr5

891270

-CEP72chr5

647920

+
intron-3UTRENST00000323510ENST00000444221BRD9chr5

891269

-CEP72chr5

647919

+
intron-3UTRENST00000388890ENST00000444221BRD9chr5

891269

-CEP72chr5

647921

+
intron-3UTRENST00000388890ENST00000444221BRD9chr5

891270

-CEP72chr5

647920

+
intron-3UTRENST00000388890ENST00000444221BRD9chr5

891269

-CEP72chr5

647919

+
intron-3UTRENST00000494422ENST00000444221BRD9chr5

891269

-CEP72chr5

647921

+
intron-3UTRENST00000494422ENST00000444221BRD9chr5

891270

-CEP72chr5

647920

+
intron-3UTRENST00000494422ENST00000444221BRD9chr5

891269

-CEP72chr5

647919

+
intron-intronENST00000323510ENST00000514507BRD9chr5

891269

-CEP72chr5

647921

+
intron-intronENST00000323510ENST00000514507BRD9chr5

891270

-CEP72chr5

647920

+
intron-intronENST00000323510ENST00000514507BRD9chr5

891269

-CEP72chr5

647919

+
intron-intronENST00000388890ENST00000514507BRD9chr5

891269

-CEP72chr5

647921

+
intron-intronENST00000388890ENST00000514507BRD9chr5

891270

-CEP72chr5

647920

+
intron-intronENST00000388890ENST00000514507BRD9chr5

891269

-CEP72chr5

647919

+
intron-intronENST00000494422ENST00000514507BRD9chr5

891269

-CEP72chr5

647921

+
intron-intronENST00000494422ENST00000514507BRD9chr5

891270

-CEP72chr5

647920

+
intron-intronENST00000494422ENST00000514507BRD9chr5

891269

-CEP72chr5

647919

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000467963BRD9chr5891269-ENST00000264935CEP72chr5647921+1245567167844225
ENST00000467963BRD9chr5891269-ENST00000264935CEP72chr5647919+1245567167844225
ENST00000467963BRD9chr5891270-ENST00000264935CEP72chr5647920+1245567167844225

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000467963ENST00000264935BRD9chr5891269-CEP72chr5647921+0.0035874780.9964126
ENST00000467963ENST00000264935BRD9chr5891269-CEP72chr5647919+0.0035874780.9964126
ENST00000467963ENST00000264935BRD9chr5891270-CEP72chr5647920+0.0035874780.9964126

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Fusion Genomic Features for BRD9-CEP72


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BRD9chr5891269-CEP72chr5647919+5.12E-091
BRD9chr5891269-CEP72chr5647919+5.12E-091
BRD9chr5891269-CEP72chr5647919+5.12E-091
BRD9chr5891269-CEP72chr5647919+5.12E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for BRD9-CEP72


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:891269/chr5:647921)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BRD9

Q9H8M2

CEP72

Q9P209

FUNCTION: Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797). Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058). Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR) (PubMed:32457312). {ECO:0000269|PubMed:22464331, ECO:0000269|PubMed:26365797, ECO:0000269|PubMed:29374058, ECO:0000269|PubMed:32457312}.FUNCTION: Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs) (PubMed:19536135). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (PubMed:26297806). {ECO:0000269|PubMed:19536135, ECO:0000269|PubMed:26297806}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBRD9chr5:891269chr5:647919ENST00000467963-31664_95133598.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:891269chr5:647921ENST00000467963-31664_95133598.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:891270chr5:647920ENST00000467963-31664_95133598.0Compositional biasNote=Lys-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBRD9chr5:891269chr5:647919ENST00000323510-11364_950502.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:891269chr5:647919ENST00000388890-11364_950482.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:891269chr5:647919ENST00000483173-31664_9582545.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:891269chr5:647921ENST00000323510-11364_950502.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:891269chr5:647921ENST00000388890-11364_950482.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:891269chr5:647921ENST00000483173-31664_9582545.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:891270chr5:647920ENST00000323510-11364_950502.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:891270chr5:647920ENST00000388890-11364_950482.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:891270chr5:647920ENST00000483173-31664_9582545.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:891269chr5:647919ENST00000323510-113153_2230502.0DomainBromo
HgeneBRD9chr5:891269chr5:647919ENST00000388890-113153_2230482.0DomainBromo
HgeneBRD9chr5:891269chr5:647919ENST00000467963-316153_223133598.0DomainBromo
HgeneBRD9chr5:891269chr5:647919ENST00000483173-316153_22382545.0DomainBromo
HgeneBRD9chr5:891269chr5:647921ENST00000323510-113153_2230502.0DomainBromo
HgeneBRD9chr5:891269chr5:647921ENST00000388890-113153_2230482.0DomainBromo
HgeneBRD9chr5:891269chr5:647921ENST00000467963-316153_223133598.0DomainBromo
HgeneBRD9chr5:891269chr5:647921ENST00000483173-316153_22382545.0DomainBromo
HgeneBRD9chr5:891270chr5:647920ENST00000323510-113153_2230502.0DomainBromo
HgeneBRD9chr5:891270chr5:647920ENST00000388890-113153_2230482.0DomainBromo
HgeneBRD9chr5:891270chr5:647920ENST00000467963-316153_223133598.0DomainBromo
HgeneBRD9chr5:891270chr5:647920ENST00000483173-316153_22382545.0DomainBromo
HgeneBRD9chr5:891269chr5:647919ENST00000323510-113214_2160502.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:891269chr5:647919ENST00000388890-113214_2160482.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:891269chr5:647919ENST00000467963-316214_216133598.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:891269chr5:647919ENST00000483173-316214_21682545.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:891269chr5:647921ENST00000323510-113214_2160502.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:891269chr5:647921ENST00000388890-113214_2160482.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:891269chr5:647921ENST00000467963-316214_216133598.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:891269chr5:647921ENST00000483173-316214_21682545.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:891270chr5:647920ENST00000323510-113214_2160502.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:891270chr5:647920ENST00000388890-113214_2160482.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:891270chr5:647920ENST00000467963-316214_216133598.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:891270chr5:647920ENST00000483173-316214_21682545.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
TgeneCEP72chr5:891269chr5:647919ENST00000264935912476_620555648.0Coiled coilOntology_term=ECO:0000255
TgeneCEP72chr5:891269chr5:647919ENST00000444221811476_620495306.3333333333333Coiled coilOntology_term=ECO:0000255
TgeneCEP72chr5:891269chr5:647921ENST00000264935912476_620555648.0Coiled coilOntology_term=ECO:0000255
TgeneCEP72chr5:891269chr5:647921ENST00000444221811476_620495306.3333333333333Coiled coilOntology_term=ECO:0000255
TgeneCEP72chr5:891270chr5:647920ENST00000264935912476_620555648.0Coiled coilOntology_term=ECO:0000255
TgeneCEP72chr5:891270chr5:647920ENST00000444221811476_620495306.3333333333333Coiled coilOntology_term=ECO:0000255
TgeneCEP72chr5:891269chr5:647919ENST00000264935912111_150555648.0DomainNote=LRRCT
TgeneCEP72chr5:891269chr5:647919ENST00000444221811111_150495306.3333333333333DomainNote=LRRCT
TgeneCEP72chr5:891269chr5:647921ENST00000264935912111_150555648.0DomainNote=LRRCT
TgeneCEP72chr5:891269chr5:647921ENST00000444221811111_150495306.3333333333333DomainNote=LRRCT
TgeneCEP72chr5:891270chr5:647920ENST00000264935912111_150555648.0DomainNote=LRRCT
TgeneCEP72chr5:891270chr5:647920ENST00000444221811111_150495306.3333333333333DomainNote=LRRCT
TgeneCEP72chr5:891269chr5:647919ENST0000026493591229_50555648.0RepeatNote=LRR 1
TgeneCEP72chr5:891269chr5:647919ENST0000026493591255_76555648.0RepeatNote=LRR 2
TgeneCEP72chr5:891269chr5:647919ENST0000026493591277_98555648.0RepeatNote=LRR 3
TgeneCEP72chr5:891269chr5:647919ENST0000044422181129_50495306.3333333333333RepeatNote=LRR 1
TgeneCEP72chr5:891269chr5:647919ENST0000044422181155_76495306.3333333333333RepeatNote=LRR 2
TgeneCEP72chr5:891269chr5:647919ENST0000044422181177_98495306.3333333333333RepeatNote=LRR 3
TgeneCEP72chr5:891269chr5:647921ENST0000026493591229_50555648.0RepeatNote=LRR 1
TgeneCEP72chr5:891269chr5:647921ENST0000026493591255_76555648.0RepeatNote=LRR 2
TgeneCEP72chr5:891269chr5:647921ENST0000026493591277_98555648.0RepeatNote=LRR 3
TgeneCEP72chr5:891269chr5:647921ENST0000044422181129_50495306.3333333333333RepeatNote=LRR 1
TgeneCEP72chr5:891269chr5:647921ENST0000044422181155_76495306.3333333333333RepeatNote=LRR 2
TgeneCEP72chr5:891269chr5:647921ENST0000044422181177_98495306.3333333333333RepeatNote=LRR 3
TgeneCEP72chr5:891270chr5:647920ENST0000026493591229_50555648.0RepeatNote=LRR 1
TgeneCEP72chr5:891270chr5:647920ENST0000026493591255_76555648.0RepeatNote=LRR 2
TgeneCEP72chr5:891270chr5:647920ENST0000026493591277_98555648.0RepeatNote=LRR 3
TgeneCEP72chr5:891270chr5:647920ENST0000044422181129_50495306.3333333333333RepeatNote=LRR 1
TgeneCEP72chr5:891270chr5:647920ENST0000044422181155_76495306.3333333333333RepeatNote=LRR 2
TgeneCEP72chr5:891270chr5:647920ENST0000044422181177_98495306.3333333333333RepeatNote=LRR 3


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Fusion Gene Sequence for BRD9-CEP72


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>10223_10223_1_BRD9-CEP72_BRD9_chr5_891269_ENST00000467963_CEP72_chr5_647919_ENST00000264935_length(transcript)=1245nt_BP=567nt
CTGCCGCGGCCCCGCCTCGCCCCGTTTCCGGCGCGGCCCAGCGAGCTCGGCAACCTCGGCGCAGCGAGCGCGGGCGGCCAGCCAGGGCCA
GGGGGCGGTGGCGGCCAAGGTCCGACCGGGTGCCAGCTGTTCCCAGCCCCCGCCTCGGGCCCGCCGCCGGCGCCGCCATGGGCAAGAAGC
ACAAGAAGCACAAGGCCGAGTGGCGCTCGTCCTACGAGGATTATGCCGACAAGCCCCTGGAGAAGCCTCTAAAGCTAGTCCTGAAGGTCG
GAGGAAGTGAAGTGACTGAACTCTCAGGATCCGGCCACGACTCCAGTTACTATGATGACAGGTCAGACCATGAGCGAGAGAGGCACAAAG
AAAAGAAAAAGAAGAAGAAGAAGAAGTCCGAGAAGGAGAAGCATCTGGACGATGAGGAAAGAAGGAAGCGAAAGGAAGAGAAGAAGCGGA
AGCGAGAGAGGGAGCACTGTGACACGGAGGGAGAGGCTGACGACTTTGATCCTGGGAAGAAGGTGGAGGTGGAGCCGCCCCCAGATCGGC
CAGTCCGAGCGTGCCGGACACAGCCAGGACTTCAAACAAGTGTGAAGAGGCTGTGTGGCGAGATTGTGGAACTGAAGCAGCACCTGGAGC
ACTACGACAAGATCCAGGAGCTCACGCAGATGCTGCAGGAGAGCCACAGCTCCCTGGTCAGCACCAATGAACACCTGCTGCAGGAGCTGA
GCCAGGTGCGGGCGCAGCACAGAGCCGAGGTGGAGCAGATGCACTGGAGCTACCAGGAGCTCAAGAAGACCATGGCCCTGTTTCCACACA
GCAGCGCCAGCCATGGAGGCTGCCAGGCCTGCTGACTCCTGCCGAGAAGCTGGGCCACCCCTTAAGCTTCCTGGTAAAGTTACATTGTCT
GCACCTTTGTACTTCTTTATTGAGTGTACTGGCTGGCAAGAGTTCTCTCTTCTGTTGGTAATTATTTAGGATTTTTGGAATGTATTCAGG
ACCTGTAGCTTGGTTTTCTAAAGCACCTCGTAAAATGATATGATTACTCCAAGCCCTCTGCATGTTTTCAGACAGAACACATTGACATAT
TTTGAGACAAACTGACTATTAATCTTGTATCCAGTATCCTGAGATGAAGTAAATGCAGTGTTCTACTGCCTGATGTGAAAGAGAGCTATG

>10223_10223_1_BRD9-CEP72_BRD9_chr5_891269_ENST00000467963_CEP72_chr5_647919_ENST00000264935_length(amino acids)=225AA_BP=133
MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKE
EKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACRTQPGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHL

--------------------------------------------------------------
>10223_10223_2_BRD9-CEP72_BRD9_chr5_891269_ENST00000467963_CEP72_chr5_647921_ENST00000264935_length(transcript)=1245nt_BP=567nt
CTGCCGCGGCCCCGCCTCGCCCCGTTTCCGGCGCGGCCCAGCGAGCTCGGCAACCTCGGCGCAGCGAGCGCGGGCGGCCAGCCAGGGCCA
GGGGGCGGTGGCGGCCAAGGTCCGACCGGGTGCCAGCTGTTCCCAGCCCCCGCCTCGGGCCCGCCGCCGGCGCCGCCATGGGCAAGAAGC
ACAAGAAGCACAAGGCCGAGTGGCGCTCGTCCTACGAGGATTATGCCGACAAGCCCCTGGAGAAGCCTCTAAAGCTAGTCCTGAAGGTCG
GAGGAAGTGAAGTGACTGAACTCTCAGGATCCGGCCACGACTCCAGTTACTATGATGACAGGTCAGACCATGAGCGAGAGAGGCACAAAG
AAAAGAAAAAGAAGAAGAAGAAGAAGTCCGAGAAGGAGAAGCATCTGGACGATGAGGAAAGAAGGAAGCGAAAGGAAGAGAAGAAGCGGA
AGCGAGAGAGGGAGCACTGTGACACGGAGGGAGAGGCTGACGACTTTGATCCTGGGAAGAAGGTGGAGGTGGAGCCGCCCCCAGATCGGC
CAGTCCGAGCGTGCCGGACACAGCCAGGACTTCAAACAAGTGTGAAGAGGCTGTGTGGCGAGATTGTGGAACTGAAGCAGCACCTGGAGC
ACTACGACAAGATCCAGGAGCTCACGCAGATGCTGCAGGAGAGCCACAGCTCCCTGGTCAGCACCAATGAACACCTGCTGCAGGAGCTGA
GCCAGGTGCGGGCGCAGCACAGAGCCGAGGTGGAGCAGATGCACTGGAGCTACCAGGAGCTCAAGAAGACCATGGCCCTGTTTCCACACA
GCAGCGCCAGCCATGGAGGCTGCCAGGCCTGCTGACTCCTGCCGAGAAGCTGGGCCACCCCTTAAGCTTCCTGGTAAAGTTACATTGTCT
GCACCTTTGTACTTCTTTATTGAGTGTACTGGCTGGCAAGAGTTCTCTCTTCTGTTGGTAATTATTTAGGATTTTTGGAATGTATTCAGG
ACCTGTAGCTTGGTTTTCTAAAGCACCTCGTAAAATGATATGATTACTCCAAGCCCTCTGCATGTTTTCAGACAGAACACATTGACATAT
TTTGAGACAAACTGACTATTAATCTTGTATCCAGTATCCTGAGATGAAGTAAATGCAGTGTTCTACTGCCTGATGTGAAAGAGAGCTATG

>10223_10223_2_BRD9-CEP72_BRD9_chr5_891269_ENST00000467963_CEP72_chr5_647921_ENST00000264935_length(amino acids)=225AA_BP=133
MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKE
EKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACRTQPGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHL

--------------------------------------------------------------
>10223_10223_3_BRD9-CEP72_BRD9_chr5_891270_ENST00000467963_CEP72_chr5_647920_ENST00000264935_length(transcript)=1245nt_BP=567nt
CTGCCGCGGCCCCGCCTCGCCCCGTTTCCGGCGCGGCCCAGCGAGCTCGGCAACCTCGGCGCAGCGAGCGCGGGCGGCCAGCCAGGGCCA
GGGGGCGGTGGCGGCCAAGGTCCGACCGGGTGCCAGCTGTTCCCAGCCCCCGCCTCGGGCCCGCCGCCGGCGCCGCCATGGGCAAGAAGC
ACAAGAAGCACAAGGCCGAGTGGCGCTCGTCCTACGAGGATTATGCCGACAAGCCCCTGGAGAAGCCTCTAAAGCTAGTCCTGAAGGTCG
GAGGAAGTGAAGTGACTGAACTCTCAGGATCCGGCCACGACTCCAGTTACTATGATGACAGGTCAGACCATGAGCGAGAGAGGCACAAAG
AAAAGAAAAAGAAGAAGAAGAAGAAGTCCGAGAAGGAGAAGCATCTGGACGATGAGGAAAGAAGGAAGCGAAAGGAAGAGAAGAAGCGGA
AGCGAGAGAGGGAGCACTGTGACACGGAGGGAGAGGCTGACGACTTTGATCCTGGGAAGAAGGTGGAGGTGGAGCCGCCCCCAGATCGGC
CAGTCCGAGCGTGCCGGACACAGCCAGGACTTCAAACAAGTGTGAAGAGGCTGTGTGGCGAGATTGTGGAACTGAAGCAGCACCTGGAGC
ACTACGACAAGATCCAGGAGCTCACGCAGATGCTGCAGGAGAGCCACAGCTCCCTGGTCAGCACCAATGAACACCTGCTGCAGGAGCTGA
GCCAGGTGCGGGCGCAGCACAGAGCCGAGGTGGAGCAGATGCACTGGAGCTACCAGGAGCTCAAGAAGACCATGGCCCTGTTTCCACACA
GCAGCGCCAGCCATGGAGGCTGCCAGGCCTGCTGACTCCTGCCGAGAAGCTGGGCCACCCCTTAAGCTTCCTGGTAAAGTTACATTGTCT
GCACCTTTGTACTTCTTTATTGAGTGTACTGGCTGGCAAGAGTTCTCTCTTCTGTTGGTAATTATTTAGGATTTTTGGAATGTATTCAGG
ACCTGTAGCTTGGTTTTCTAAAGCACCTCGTAAAATGATATGATTACTCCAAGCCCTCTGCATGTTTTCAGACAGAACACATTGACATAT
TTTGAGACAAACTGACTATTAATCTTGTATCCAGTATCCTGAGATGAAGTAAATGCAGTGTTCTACTGCCTGATGTGAAAGAGAGCTATG

>10223_10223_3_BRD9-CEP72_BRD9_chr5_891270_ENST00000467963_CEP72_chr5_647920_ENST00000264935_length(amino acids)=225AA_BP=133
MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKE
EKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACRTQPGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHL

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Fusion Gene PPI Analysis for BRD9-CEP72


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BRD9-CEP72


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BRD9-CEP72


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource