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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF511-PPAPDC1A (FusionGDB2 ID:102230)

Fusion Gene Summary for ZNF511-PPAPDC1A

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF511-PPAPDC1A
Fusion gene ID: 102230
HgeneTgene
Gene symbol

ZNF511

PPAPDC1A

Gene ID

118472

196051

Gene namezinc finger protein 511phospholipid phosphatase 4
SynonymsZfp511DPPL2|PPAPDC1|PPAPDC1A
Cytomap

10q26.3

10q26.12

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 511phospholipid phosphatase 4diacylglycerol pyrophosphate like 2diacylglycerol pyrophosphate phosphatase-like 2phosphatidate phosphatase PPAPDC1Aphosphatidic acid phosphatase type 2 domain containing 1Aphosphatidic acid phosphatase type 2 domain-contain
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000463816, ENST00000359035, 
ENST00000361518, ENST00000368554, 
ENST00000369073, ENST00000398248, 
ENST00000398250, ENST00000439221, 
ENST00000541332, ENST00000496437, 
Fusion gene scores* DoF score2 X 1 X 2=48 X 6 X 6=288
# samples 213
** MAII scorelog2(2/4*10)=2.32192809488736log2(13/288*10)=-1.14755718841386
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF511 [Title/Abstract] AND PPAPDC1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF511(135125345)-PPAPDC1A(122263330), # samples:1
Anticipated loss of major functional domain due to fusion event.ZNF511-PPAPDC1A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ZNF511-PPAPDC1A seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePPAPDC1A

GO:0046839

phospholipid dephosphorylation

17590538


check buttonFusion gene breakpoints across ZNF511 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PPAPDC1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A8BM-01AZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+


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Fusion Gene ORF analysis for ZNF511-PPAPDC1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000463816ENST00000369073ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
3UTR-3CDSENST00000463816ENST00000398248ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
3UTR-3CDSENST00000463816ENST00000398250ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
3UTR-3CDSENST00000463816ENST00000439221ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
3UTR-3CDSENST00000463816ENST00000541332ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
3UTR-intronENST00000463816ENST00000496437ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
5CDS-intronENST00000359035ENST00000496437ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
5CDS-intronENST00000361518ENST00000496437ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
5CDS-intronENST00000368554ENST00000496437ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
Frame-shiftENST00000359035ENST00000369073ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
Frame-shiftENST00000359035ENST00000398248ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
Frame-shiftENST00000359035ENST00000398250ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
Frame-shiftENST00000359035ENST00000439221ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
Frame-shiftENST00000359035ENST00000541332ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
In-frameENST00000361518ENST00000369073ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
In-frameENST00000361518ENST00000398248ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
In-frameENST00000361518ENST00000398250ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
In-frameENST00000361518ENST00000439221ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
In-frameENST00000361518ENST00000541332ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
In-frameENST00000368554ENST00000369073ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
In-frameENST00000368554ENST00000398248ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
In-frameENST00000368554ENST00000398250ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
In-frameENST00000368554ENST00000439221ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+
In-frameENST00000368554ENST00000541332ZNF511chr10

135125345

-PPAPDC1Achr10

122263330

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000368554ZNF511chr10135125345-ENST00000398250PPAPDC1Achr10122263330+1620507221266414
ENST00000368554ZNF511chr10135125345-ENST00000439221PPAPDC1Achr10122263330+1431507221077351
ENST00000368554ZNF511chr10135125345-ENST00000398248PPAPDC1Achr10122263330+116950722741239
ENST00000368554ZNF511chr10135125345-ENST00000541332PPAPDC1Achr10122263330+1816507221152376
ENST00000368554ZNF511chr10135125345-ENST00000369073PPAPDC1Achr10122263330+1616507221266414
ENST00000361518ZNF511chr10135125345-ENST00000398250PPAPDC1Achr10122263330+226211494451908487
ENST00000361518ZNF511chr10135125345-ENST00000439221PPAPDC1Achr10122263330+207311494451719424
ENST00000361518ZNF511chr10135125345-ENST00000398248PPAPDC1Achr10122263330+181111494451383312
ENST00000361518ZNF511chr10135125345-ENST00000541332PPAPDC1Achr10122263330+245811494451794449
ENST00000361518ZNF511chr10135125345-ENST00000369073PPAPDC1Achr10122263330+225811494451908487

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000368554ENST00000398250ZNF511chr10135125345-PPAPDC1Achr10122263330+0.0044376780.9955623
ENST00000368554ENST00000439221ZNF511chr10135125345-PPAPDC1Achr10122263330+0.0042117730.9957883
ENST00000368554ENST00000398248ZNF511chr10135125345-PPAPDC1Achr10122263330+0.0161744840.9838255
ENST00000368554ENST00000541332ZNF511chr10135125345-PPAPDC1Achr10122263330+0.0230754690.97692454
ENST00000368554ENST00000369073ZNF511chr10135125345-PPAPDC1Achr10122263330+0.0045978970.9954021
ENST00000361518ENST00000398250ZNF511chr10135125345-PPAPDC1Achr10122263330+0.0057678350.9942321
ENST00000361518ENST00000439221ZNF511chr10135125345-PPAPDC1Achr10122263330+0.0080032030.9919968
ENST00000361518ENST00000398248ZNF511chr10135125345-PPAPDC1Achr10122263330+0.0238347740.9761653
ENST00000361518ENST00000541332ZNF511chr10135125345-PPAPDC1Achr10122263330+0.0241960230.975804
ENST00000361518ENST00000369073ZNF511chr10135125345-PPAPDC1Achr10122263330+0.005918190.9940818

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Fusion Genomic Features for ZNF511-PPAPDC1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZNF511-PPAPDC1A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:135125345/chr10:122263330)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF511chr10:135125345chr10:122263330ENST00000361518-56107_130226253.0Zinc fingerNote=C2H2-type 2
HgeneZNF511chr10:135125345chr10:122263330ENST00000361518-56144_169226253.0Zinc fingerNote=C2H2-type 3
HgeneZNF511chr10:135125345chr10:122263330ENST00000361518-5680_105226253.0Zinc fingerNote=C2H2-type 1
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039824803102_1101897.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039824803143_1461897.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039824803195_2051897.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039825007102_11018272.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039825007143_14618272.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039825007195_20518272.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000043922105102_11018209.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000043922105143_14618209.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000043922105195_20518209.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039824803142_1621897.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039824803179_1991897.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039824803202_2221897.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST000003982480349_691897.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST000003982480384_1041897.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039825007142_16218272.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039825007179_19918272.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000039825007202_22218272.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST000003982500749_6918272.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST000003982500784_10418272.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000043922105142_16218209.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000043922105179_19918209.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST0000043922105202_22218209.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST000004392210549_6918209.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST000004392210584_10418209.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF511chr10:135125345chr10:122263330ENST00000359035-15107_1300263.0Zinc fingerNote=C2H2-type 2
HgeneZNF511chr10:135125345chr10:122263330ENST00000359035-15144_1690263.0Zinc fingerNote=C2H2-type 3
HgeneZNF511chr10:135125345chr10:122263330ENST00000359035-1580_1050263.0Zinc fingerNote=C2H2-type 1
TgenePPAPDC1Achr10:135125345chr10:122263330ENST00000398248034_241897.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST00000398250074_2418272.0TransmembraneHelical
TgenePPAPDC1Achr10:135125345chr10:122263330ENST00000439221054_2418209.0TransmembraneHelical


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Fusion Gene Sequence for ZNF511-PPAPDC1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102230_102230_1_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000361518_PPAPDC1A_chr10_122263330_ENST00000369073_length(transcript)=2258nt_BP=1149nt
CCAGGGACTGCAGCGGGAGACGACAGGCGGGGCAAGGCGGACGGGAGAGGGCGTGCGAGAGGGGGACCTGCGACCCGGCTTCCCAGGGCT
GGGAGGGGACACCCGGGACGACCCGGAGGCCCGCTCCGCCCCGCCCCGGCTGAGTGTCGGGCCGCGGGGCAAGACGCTGGCCTGGCCGGT
GCAGGCCCGAAGGGCTTCGGCCCCAGAGTTCGGGGACCGCTGCACAGCCAGAGGGAGCGCGCGGGAAGAGCCGCGTCCCGCCAGCCCCGT
CGCCTCGTGGGCCCCCCCGGGCCTGGCAGTCCCCCAACCCCCTCATCACGCCCGCGCCCGCGTTCGGCCAGGACTCACCGCAGTCCCGGA
GCCACAGCCCCCGCGCAGCCCCCGACGGCGGCGGAAGTGAGCGTGACGTCACGTCCGGCTCGGCTCGCGGACGGTGGCCGACAGGCTGCG
CCCGCCCGCGCCCGGGGTGATGCAGTTGCCCCCCGCGCTGTGCGCCCGCCTCGCTGCGGGGCCCGGGGCGGCGGAGCCGCTGCCTGTAGA
GCGGGATCCCGCGGCTGGGGCCGCGCCCTTTCGCTTCGTTGCGCGCCCCGTGCGCTTCCCGCGGGAGCACCAGTTCTTCGAGGATGGGGA
CGTGCAGCGCCACCTCTACCTCCAGGACGTGATCATGCAGGTGGCCGACGTGCCTGAGAAGCCCAGGGTGCCCGCGTTTGCCTGCCAGGT
GGCCGGCTGCTGCCAGGTGTTCGATGCCCTGGACGACTACGAGCACCACTACCACACGCTGCACGGAAATGTTTGCTCCTTTTGCAAGCG
GGCCTTCCCTTCCGGACACCTGCTGGACGCCCACATCCTGGAGTGGCACGATTCGCTCTTCCAGATCCTGTCTGAGAGGCAGGACATGTA
TCAGTGCTTGGTAGAAGGCTGCACAGAGAAGTTCAAGACCAGCAGAGACCGGAAGGATCACATGGTGAGGATGCACCTGTACCCCGCGGA
CTTCCGGTTTGATAAGCCAAAGAAAAGCAGAAGCCCAGCCTCAGCAGAAGCCCCAGGGGACAGTGGAGAGCGGTCAGAAGGGGAGGCCAT
GGAAATCTGCTCTGAGCCTGTGGCAGCCTCCCCTGCACCGGCAGGTGAGAGGCGGATCTACAGACATAGTTTTACAGAGTTTTTGGATCC
GTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGC
AATTTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGC
GGTGTCCTTGGCTCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTG
CTTTCCAGATGGAGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCA
TTCCTCCTTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAG
CTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGA
TTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAA
ACCCTACGTTAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGAT
CACCGAAGGCCCGGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAA
TGGTTTTCTGTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAA
ATGTCTACTTCCAACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGG
AGCTTGGCCGATTCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACG

>102230_102230_1_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000361518_PPAPDC1A_chr10_122263330_ENST00000369073_length(amino acids)=487AA_BP=234
MRPPAPGVMQLPPALCARLAAGPGAAEPLPVERDPAAGAAPFRFVARPVRFPREHQFFEDGDVQRHLYLQDVIMQVADVPEKPRVPAFAC
QVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQDMYQCLVEGCTEKFKTSRDRKDHMVRMHLYP
ADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHSFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLM
FAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPS
IHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTAC

--------------------------------------------------------------
>102230_102230_2_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000361518_PPAPDC1A_chr10_122263330_ENST00000398248_length(transcript)=1811nt_BP=1149nt
CCAGGGACTGCAGCGGGAGACGACAGGCGGGGCAAGGCGGACGGGAGAGGGCGTGCGAGAGGGGGACCTGCGACCCGGCTTCCCAGGGCT
GGGAGGGGACACCCGGGACGACCCGGAGGCCCGCTCCGCCCCGCCCCGGCTGAGTGTCGGGCCGCGGGGCAAGACGCTGGCCTGGCCGGT
GCAGGCCCGAAGGGCTTCGGCCCCAGAGTTCGGGGACCGCTGCACAGCCAGAGGGAGCGCGCGGGAAGAGCCGCGTCCCGCCAGCCCCGT
CGCCTCGTGGGCCCCCCCGGGCCTGGCAGTCCCCCAACCCCCTCATCACGCCCGCGCCCGCGTTCGGCCAGGACTCACCGCAGTCCCGGA
GCCACAGCCCCCGCGCAGCCCCCGACGGCGGCGGAAGTGAGCGTGACGTCACGTCCGGCTCGGCTCGCGGACGGTGGCCGACAGGCTGCG
CCCGCCCGCGCCCGGGGTGATGCAGTTGCCCCCCGCGCTGTGCGCCCGCCTCGCTGCGGGGCCCGGGGCGGCGGAGCCGCTGCCTGTAGA
GCGGGATCCCGCGGCTGGGGCCGCGCCCTTTCGCTTCGTTGCGCGCCCCGTGCGCTTCCCGCGGGAGCACCAGTTCTTCGAGGATGGGGA
CGTGCAGCGCCACCTCTACCTCCAGGACGTGATCATGCAGGTGGCCGACGTGCCTGAGAAGCCCAGGGTGCCCGCGTTTGCCTGCCAGGT
GGCCGGCTGCTGCCAGGTGTTCGATGCCCTGGACGACTACGAGCACCACTACCACACGCTGCACGGAAATGTTTGCTCCTTTTGCAAGCG
GGCCTTCCCTTCCGGACACCTGCTGGACGCCCACATCCTGGAGTGGCACGATTCGCTCTTCCAGATCCTGTCTGAGAGGCAGGACATGTA
TCAGTGCTTGGTAGAAGGCTGCACAGAGAAGTTCAAGACCAGCAGAGACCGGAAGGATCACATGGTGAGGATGCACCTGTACCCCGCGGA
CTTCCGGTTTGATAAGCCAAAGAAAAGCAGAAGCCCAGCCTCAGCAGAAGCCCCAGGGGACAGTGGAGAGCGGTCAGAAGGGGAGGCCAT
GGAAATCTGCTCTGAGCCTGTGGCAGCCTCCCCTGCACCGGCAGGTGAGAGGCGGATCTACAGACATAGTTTTACAGAGTTTTTGGATCC
GTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTAT
TCCTTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAA
CCCTACGTTAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATC
ACCGAAGGCCCGGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAAT
GGTTTTCTGTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAA
TGTCTACTTCCAACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGA
GCTTGGCCGATTCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGT

>102230_102230_2_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000361518_PPAPDC1A_chr10_122263330_ENST00000398248_length(amino acids)=312AA_BP=234
MRPPAPGVMQLPPALCARLAAGPGAAEPLPVERDPAAGAAPFRFVARPVRFPREHQFFEDGDVQRHLYLQDVIMQVADVPEKPRVPAFAC
QVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQDMYQCLVEGCTEKFKTSRDRKDHMVRMHLYP
ADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHSFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLM

--------------------------------------------------------------
>102230_102230_3_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000361518_PPAPDC1A_chr10_122263330_ENST00000398250_length(transcript)=2262nt_BP=1149nt
CCAGGGACTGCAGCGGGAGACGACAGGCGGGGCAAGGCGGACGGGAGAGGGCGTGCGAGAGGGGGACCTGCGACCCGGCTTCCCAGGGCT
GGGAGGGGACACCCGGGACGACCCGGAGGCCCGCTCCGCCCCGCCCCGGCTGAGTGTCGGGCCGCGGGGCAAGACGCTGGCCTGGCCGGT
GCAGGCCCGAAGGGCTTCGGCCCCAGAGTTCGGGGACCGCTGCACAGCCAGAGGGAGCGCGCGGGAAGAGCCGCGTCCCGCCAGCCCCGT
CGCCTCGTGGGCCCCCCCGGGCCTGGCAGTCCCCCAACCCCCTCATCACGCCCGCGCCCGCGTTCGGCCAGGACTCACCGCAGTCCCGGA
GCCACAGCCCCCGCGCAGCCCCCGACGGCGGCGGAAGTGAGCGTGACGTCACGTCCGGCTCGGCTCGCGGACGGTGGCCGACAGGCTGCG
CCCGCCCGCGCCCGGGGTGATGCAGTTGCCCCCCGCGCTGTGCGCCCGCCTCGCTGCGGGGCCCGGGGCGGCGGAGCCGCTGCCTGTAGA
GCGGGATCCCGCGGCTGGGGCCGCGCCCTTTCGCTTCGTTGCGCGCCCCGTGCGCTTCCCGCGGGAGCACCAGTTCTTCGAGGATGGGGA
CGTGCAGCGCCACCTCTACCTCCAGGACGTGATCATGCAGGTGGCCGACGTGCCTGAGAAGCCCAGGGTGCCCGCGTTTGCCTGCCAGGT
GGCCGGCTGCTGCCAGGTGTTCGATGCCCTGGACGACTACGAGCACCACTACCACACGCTGCACGGAAATGTTTGCTCCTTTTGCAAGCG
GGCCTTCCCTTCCGGACACCTGCTGGACGCCCACATCCTGGAGTGGCACGATTCGCTCTTCCAGATCCTGTCTGAGAGGCAGGACATGTA
TCAGTGCTTGGTAGAAGGCTGCACAGAGAAGTTCAAGACCAGCAGAGACCGGAAGGATCACATGGTGAGGATGCACCTGTACCCCGCGGA
CTTCCGGTTTGATAAGCCAAAGAAAAGCAGAAGCCCAGCCTCAGCAGAAGCCCCAGGGGACAGTGGAGAGCGGTCAGAAGGGGAGGCCAT
GGAAATCTGCTCTGAGCCTGTGGCAGCCTCCCCTGCACCGGCAGGTGAGAGGCGGATCTACAGACATAGTTTTACAGAGTTTTTGGATCC
GTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGC
AATTTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGC
GGTGTCCTTGGCTCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTG
CTTTCCAGATGGAGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCA
TTCCTCCTTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAG
CTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGA
TTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAA
ACCCTACGTTAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGAT
CACCGAAGGCCCGGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAA
TGGTTTTCTGTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAA
ATGTCTACTTCCAACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGG
AGCTTGGCCGATTCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACG

>102230_102230_3_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000361518_PPAPDC1A_chr10_122263330_ENST00000398250_length(amino acids)=487AA_BP=234
MRPPAPGVMQLPPALCARLAAGPGAAEPLPVERDPAAGAAPFRFVARPVRFPREHQFFEDGDVQRHLYLQDVIMQVADVPEKPRVPAFAC
QVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQDMYQCLVEGCTEKFKTSRDRKDHMVRMHLYP
ADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHSFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLM
FAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPS
IHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTAC

--------------------------------------------------------------
>102230_102230_4_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000361518_PPAPDC1A_chr10_122263330_ENST00000439221_length(transcript)=2073nt_BP=1149nt
CCAGGGACTGCAGCGGGAGACGACAGGCGGGGCAAGGCGGACGGGAGAGGGCGTGCGAGAGGGGGACCTGCGACCCGGCTTCCCAGGGCT
GGGAGGGGACACCCGGGACGACCCGGAGGCCCGCTCCGCCCCGCCCCGGCTGAGTGTCGGGCCGCGGGGCAAGACGCTGGCCTGGCCGGT
GCAGGCCCGAAGGGCTTCGGCCCCAGAGTTCGGGGACCGCTGCACAGCCAGAGGGAGCGCGCGGGAAGAGCCGCGTCCCGCCAGCCCCGT
CGCCTCGTGGGCCCCCCCGGGCCTGGCAGTCCCCCAACCCCCTCATCACGCCCGCGCCCGCGTTCGGCCAGGACTCACCGCAGTCCCGGA
GCCACAGCCCCCGCGCAGCCCCCGACGGCGGCGGAAGTGAGCGTGACGTCACGTCCGGCTCGGCTCGCGGACGGTGGCCGACAGGCTGCG
CCCGCCCGCGCCCGGGGTGATGCAGTTGCCCCCCGCGCTGTGCGCCCGCCTCGCTGCGGGGCCCGGGGCGGCGGAGCCGCTGCCTGTAGA
GCGGGATCCCGCGGCTGGGGCCGCGCCCTTTCGCTTCGTTGCGCGCCCCGTGCGCTTCCCGCGGGAGCACCAGTTCTTCGAGGATGGGGA
CGTGCAGCGCCACCTCTACCTCCAGGACGTGATCATGCAGGTGGCCGACGTGCCTGAGAAGCCCAGGGTGCCCGCGTTTGCCTGCCAGGT
GGCCGGCTGCTGCCAGGTGTTCGATGCCCTGGACGACTACGAGCACCACTACCACACGCTGCACGGAAATGTTTGCTCCTTTTGCAAGCG
GGCCTTCCCTTCCGGACACCTGCTGGACGCCCACATCCTGGAGTGGCACGATTCGCTCTTCCAGATCCTGTCTGAGAGGCAGGACATGTA
TCAGTGCTTGGTAGAAGGCTGCACAGAGAAGTTCAAGACCAGCAGAGACCGGAAGGATCACATGGTGAGGATGCACCTGTACCCCGCGGA
CTTCCGGTTTGATAAGCCAAAGAAAAGCAGAAGCCCAGCCTCAGCAGAAGCCCCAGGGGACAGTGGAGAGCGGTCAGAAGGGGAGGCCAT
GGAAATCTGCTCTGAGCCTGTGGCAGCCTCCCCTGCACCGGCAGGTGAGAGGCGGATCTACAGACATAGTTTTACAGAGTTTTTGGATCC
GTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGC
AATTTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGT
TGCCTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCT
CTGTGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGT
GGGTGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGT
TAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGG
CCCGGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCT
GTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACT
TCCAACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCC
GATTCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGGAAGACT

>102230_102230_4_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000361518_PPAPDC1A_chr10_122263330_ENST00000439221_length(amino acids)=424AA_BP=234
MRPPAPGVMQLPPALCARLAAGPGAAEPLPVERDPAAGAAPFRFVARPVRFPREHQFFEDGDVQRHLYLQDVIMQVADVPEKPRVPAFAC
QVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQDMYQCLVEGCTEKFKTSRDRKDHMVRMHLYP
ADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHSFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLM
FAISFLTPLAVICVVKIIRRTDKTEIKEAFLVAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDS

--------------------------------------------------------------
>102230_102230_5_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000361518_PPAPDC1A_chr10_122263330_ENST00000541332_length(transcript)=2458nt_BP=1149nt
CCAGGGACTGCAGCGGGAGACGACAGGCGGGGCAAGGCGGACGGGAGAGGGCGTGCGAGAGGGGGACCTGCGACCCGGCTTCCCAGGGCT
GGGAGGGGACACCCGGGACGACCCGGAGGCCCGCTCCGCCCCGCCCCGGCTGAGTGTCGGGCCGCGGGGCAAGACGCTGGCCTGGCCGGT
GCAGGCCCGAAGGGCTTCGGCCCCAGAGTTCGGGGACCGCTGCACAGCCAGAGGGAGCGCGCGGGAAGAGCCGCGTCCCGCCAGCCCCGT
CGCCTCGTGGGCCCCCCCGGGCCTGGCAGTCCCCCAACCCCCTCATCACGCCCGCGCCCGCGTTCGGCCAGGACTCACCGCAGTCCCGGA
GCCACAGCCCCCGCGCAGCCCCCGACGGCGGCGGAAGTGAGCGTGACGTCACGTCCGGCTCGGCTCGCGGACGGTGGCCGACAGGCTGCG
CCCGCCCGCGCCCGGGGTGATGCAGTTGCCCCCCGCGCTGTGCGCCCGCCTCGCTGCGGGGCCCGGGGCGGCGGAGCCGCTGCCTGTAGA
GCGGGATCCCGCGGCTGGGGCCGCGCCCTTTCGCTTCGTTGCGCGCCCCGTGCGCTTCCCGCGGGAGCACCAGTTCTTCGAGGATGGGGA
CGTGCAGCGCCACCTCTACCTCCAGGACGTGATCATGCAGGTGGCCGACGTGCCTGAGAAGCCCAGGGTGCCCGCGTTTGCCTGCCAGGT
GGCCGGCTGCTGCCAGGTGTTCGATGCCCTGGACGACTACGAGCACCACTACCACACGCTGCACGGAAATGTTTGCTCCTTTTGCAAGCG
GGCCTTCCCTTCCGGACACCTGCTGGACGCCCACATCCTGGAGTGGCACGATTCGCTCTTCCAGATCCTGTCTGAGAGGCAGGACATGTA
TCAGTGCTTGGTAGAAGGCTGCACAGAGAAGTTCAAGACCAGCAGAGACCGGAAGGATCACATGGTGAGGATGCACCTGTACCCCGCGGA
CTTCCGGTTTGATAAGCCAAAGAAAAGCAGAAGCCCAGCCTCAGCAGAAGCCCCAGGGGACAGTGGAGAGCGGTCAGAAGGGGAGGCCAT
GGAAATCTGCTCTGAGCCTGTGGCAGCCTCCCCTGCACCGGCAGGTGAGAGGCGGATCTACAGACATAGTTTTACAGAGTTTTTGGATCC
GTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGC
AATTTCTTTCCTCACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGC
GGTGTCCTTGGCTCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTG
CTTTCCAGATGGAGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCA
TTCCTCCTTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAG
CTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGT
TGGCTGCTGTGTATGGCAGGGCCCACAGTCACATTTACCATCGGCTGCCAACCCCCGCCTCTGTCTGGGAACCTCTGAACCTTGACTGCC
CATCTAAGTCCACCCGCCTCTGTGTTGGTGCCTAGGAGAGCGTAAGAAGCCTCAGCCCCTGGCTCACCCCTCCCTCCGGTCAAAGTCCAC
TGCATATCCTGCTTTCAGCCTCAAGAGAGGCATTCTCAGTCAGGACTTCTGCCCTCTTCCTGCCTCCAGGATAGCCCTGGTGTTTCCCCG
TGATGTAATTCCCAGGGAAGATGGACGTTGATTGCTCCCAAGTCTCACTGGCATCCTTCCTTTGTTTTACTCAAGGGAACCTGTCTCTTC
TCAGCTTTCTGTGGTGTTCTGTGGTTCCTCCTGCTCAGCATATTTATAGACTCCAACTTTTCCTTCCCACTCTGGTCTAGTGATCCTCAG
TTGTTGCCTGAATCATTGCAGAAGCCTCTCAGCCTGGCTCCCTCCTTCCTTCTTTGGCCCTCAACTGCATTTGGAATGTGCCTTTAGAGC
CTGCGTTAGCACATGTCACTTTTGCAAAAATCCTCCAGTGATTCTCATTTCACTCAGCATCACAGCCTGTGTCCTGCCATGGTCCATAAG
ATCTGCTCCCTCCGTACTTCTTTGATGCTATGTTCAAGCTACTTGTCCTCCTCGTTCACATGATTGCATCGCTTGAGCTTCTTGCTACTC

>102230_102230_5_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000361518_PPAPDC1A_chr10_122263330_ENST00000541332_length(amino acids)=449AA_BP=234
MRPPAPGVMQLPPALCARLAAGPGAAEPLPVERDPAAGAAPFRFVARPVRFPREHQFFEDGDVQRHLYLQDVIMQVADVPEKPRVPAFAC
QVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQDMYQCLVEGCTEKFKTSRDRKDHMVRMHLYP
ADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHSFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLM
FAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPS

--------------------------------------------------------------
>102230_102230_6_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000368554_PPAPDC1A_chr10_122263330_ENST00000369073_length(transcript)=1616nt_BP=507nt
CCTCTACCTCCAGGACGTGATCATGCAGGTGGCCGACGTGCCTGAGAAGCCCAGGGTGCCCGCGTTTGCCTGCCAGGTGGCCGGCTGCTG
CCAGGTGTTCGATGCCCTGGACGACTACGAGCACCACTACCACACGCTGCACGGAAATGTTTGCTCCTTTTGCAAGCGGGCCTTCCCTTC
CGGACACCTGCTGGACGCCCACATCCTGGAGTGGCACGATTCGCTCTTCCAGATCCTGTCTGAGAGGCAGGACATGTATCAGTGCTTGGT
AGAAGGCTGCACAGAGAAGTTCAAGACCAGCAGAGACCGGAAGGATCACATGGTGAGGATGCACCTGTACCCCGCGGACTTCCGGTTTGA
TAAGCCAAAGAAAAGCAGAAGCCCAGCCTCAGCAGAAGCCCCAGGGGACAGTGGAGAGCGGTCAGAAGGGGAGGCCATGGAAATCTGCTC
TGAGCCTGTGGCAGCCTCCCCTGCACCGGCAGGTGAGAGGCGGATCTACAGACATAGTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGT
CATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCT
CACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGC
TCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGG
AGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGC
CTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTG
TGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGG
TGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAG
TCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCC
GGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTA
GTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCC
AACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGAT

>102230_102230_6_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000368554_PPAPDC1A_chr10_122263330_ENST00000369073_length(amino acids)=414AA_BP=161
MQVADVPEKPRVPAFACQVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQDMYQCLVEGCTEKF
KTSRDRKDHMVRMHLYPADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHSFTEFLDPFQRVIQPEEIW
LYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMH
CTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIF

--------------------------------------------------------------
>102230_102230_7_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000368554_PPAPDC1A_chr10_122263330_ENST00000398248_length(transcript)=1169nt_BP=507nt
CCTCTACCTCCAGGACGTGATCATGCAGGTGGCCGACGTGCCTGAGAAGCCCAGGGTGCCCGCGTTTGCCTGCCAGGTGGCCGGCTGCTG
CCAGGTGTTCGATGCCCTGGACGACTACGAGCACCACTACCACACGCTGCACGGAAATGTTTGCTCCTTTTGCAAGCGGGCCTTCCCTTC
CGGACACCTGCTGGACGCCCACATCCTGGAGTGGCACGATTCGCTCTTCCAGATCCTGTCTGAGAGGCAGGACATGTATCAGTGCTTGGT
AGAAGGCTGCACAGAGAAGTTCAAGACCAGCAGAGACCGGAAGGATCACATGGTGAGGATGCACCTGTACCCCGCGGACTTCCGGTTTGA
TAAGCCAAAGAAAAGCAGAAGCCCAGCCTCAGCAGAAGCCCCAGGGGACAGTGGAGAGCGGTCAGAAGGGGAGGCCATGGAAATCTGCTC
TGAGCCTGTGGCAGCCTCCCCTGCACCGGCAGGTGAGAGGCGGATCTACAGACATAGTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGT
CATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTATTCCTTTGTGGGT
GGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGT
CTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCG
GTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAG
TGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCA
ACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATT

>102230_102230_7_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000368554_PPAPDC1A_chr10_122263330_ENST00000398248_length(amino acids)=239AA_BP=161
MQVADVPEKPRVPAFACQVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQDMYQCLVEGCTEKF
KTSRDRKDHMVRMHLYPADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHSFTEFLDPFQRVIQPEEIW

--------------------------------------------------------------
>102230_102230_8_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000368554_PPAPDC1A_chr10_122263330_ENST00000398250_length(transcript)=1620nt_BP=507nt
CCTCTACCTCCAGGACGTGATCATGCAGGTGGCCGACGTGCCTGAGAAGCCCAGGGTGCCCGCGTTTGCCTGCCAGGTGGCCGGCTGCTG
CCAGGTGTTCGATGCCCTGGACGACTACGAGCACCACTACCACACGCTGCACGGAAATGTTTGCTCCTTTTGCAAGCGGGCCTTCCCTTC
CGGACACCTGCTGGACGCCCACATCCTGGAGTGGCACGATTCGCTCTTCCAGATCCTGTCTGAGAGGCAGGACATGTATCAGTGCTTGGT
AGAAGGCTGCACAGAGAAGTTCAAGACCAGCAGAGACCGGAAGGATCACATGGTGAGGATGCACCTGTACCCCGCGGACTTCCGGTTTGA
TAAGCCAAAGAAAAGCAGAAGCCCAGCCTCAGCAGAAGCCCCAGGGGACAGTGGAGAGCGGTCAGAAGGGGAGGCCATGGAAATCTGCTC
TGAGCCTGTGGCAGCCTCCCCTGCACCGGCAGGTGAGAGGCGGATCTACAGACATAGTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGT
CATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCT
CACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGC
TCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGG
AGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGC
CTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTG
TGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGG
TGGAGTCATCGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAG
TCTGCGAGTCCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCC
GGTATGACCAGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTA
GTGTATTTTTCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCC
AACATCCTTGAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGAT
TCGTCTATCTGAAATGTTTGCTGTAACAGCCACCTTCCTATGTTTTCATGGTTGTAAAACATAATAAAACCTCCCACGTGGAAGACTTGG

>102230_102230_8_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000368554_PPAPDC1A_chr10_122263330_ENST00000398250_length(amino acids)=414AA_BP=161
MQVADVPEKPRVPAFACQVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQDMYQCLVEGCTEKF
KTSRDRKDHMVRMHLYPADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHSFTEFLDPFQRVIQPEEIW
LYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMH
CTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIF

--------------------------------------------------------------
>102230_102230_9_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000368554_PPAPDC1A_chr10_122263330_ENST00000439221_length(transcript)=1431nt_BP=507nt
CCTCTACCTCCAGGACGTGATCATGCAGGTGGCCGACGTGCCTGAGAAGCCCAGGGTGCCCGCGTTTGCCTGCCAGGTGGCCGGCTGCTG
CCAGGTGTTCGATGCCCTGGACGACTACGAGCACCACTACCACACGCTGCACGGAAATGTTTGCTCCTTTTGCAAGCGGGCCTTCCCTTC
CGGACACCTGCTGGACGCCCACATCCTGGAGTGGCACGATTCGCTCTTCCAGATCCTGTCTGAGAGGCAGGACATGTATCAGTGCTTGGT
AGAAGGCTGCACAGAGAAGTTCAAGACCAGCAGAGACCGGAAGGATCACATGGTGAGGATGCACCTGTACCCCGCGGACTTCCGGTTTGA
TAAGCCAAAGAAAAGCAGAAGCCCAGCCTCAGCAGAAGCCCCAGGGGACAGTGGAGAGCGGTCAGAAGGGGAGGCCATGGAAATCTGCTC
TGAGCCTGTGGCAGCCTCCCCTGCACCGGCAGGTGAGAGGCGGATCTACAGACATAGTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGT
CATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCT
CACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGTTGCCTTTTCGGG
CCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCAT
CCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGGTGGAGTCAT
CGGCCTCATTTTTGCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGT
CCCAGCCTCACTGAAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACC
AGTGTCCTGGGAGGATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTT
TCATCAGTTGTTTCTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTT
GAATTTGCAAGTGAAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATC

>102230_102230_9_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000368554_PPAPDC1A_chr10_122263330_ENST00000439221_length(amino acids)=351AA_BP=161
MQVADVPEKPRVPAFACQVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQDMYQCLVEGCTEKF
KTSRDRKDHMVRMHLYPADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHSFTEFLDPFQRVIQPEEIW
LYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLVAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAM

--------------------------------------------------------------
>102230_102230_10_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000368554_PPAPDC1A_chr10_122263330_ENST00000541332_length(transcript)=1816nt_BP=507nt
CCTCTACCTCCAGGACGTGATCATGCAGGTGGCCGACGTGCCTGAGAAGCCCAGGGTGCCCGCGTTTGCCTGCCAGGTGGCCGGCTGCTG
CCAGGTGTTCGATGCCCTGGACGACTACGAGCACCACTACCACACGCTGCACGGAAATGTTTGCTCCTTTTGCAAGCGGGCCTTCCCTTC
CGGACACCTGCTGGACGCCCACATCCTGGAGTGGCACGATTCGCTCTTCCAGATCCTGTCTGAGAGGCAGGACATGTATCAGTGCTTGGT
AGAAGGCTGCACAGAGAAGTTCAAGACCAGCAGAGACCGGAAGGATCACATGGTGAGGATGCACCTGTACCCCGCGGACTTCCGGTTTGA
TAAGCCAAAGAAAAGCAGAAGCCCAGCCTCAGCAGAAGCCCCAGGGGACAGTGGAGAGCGGTCAGAAGGGGAGGCCATGGAAATCTGCTC
TGAGCCTGTGGCAGCCTCCCCTGCACCGGCAGGTGAGAGGCGGATCTACAGACATAGTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGT
CATCCAGCCAGAAGAGATCTGGCTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCT
CACACCCCTGGCTGTTATTTGTGTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGC
TCTTGCTTTGAATGGAGTCTGCACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGG
AGTGATGAACTCGGAAATGCATTGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGC
CTTTTCGGGCCTTGGCTTCACGACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTG
TGCTGCCATCCTGCCCTTGTACTGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGTTGGCTGCTGTGT
ATGGCAGGGCCCACAGTCACATTTACCATCGGCTGCCAACCCCCGCCTCTGTCTGGGAACCTCTGAACCTTGACTGCCCATCTAAGTCCA
CCCGCCTCTGTGTTGGTGCCTAGGAGAGCGTAAGAAGCCTCAGCCCCTGGCTCACCCCTCCCTCCGGTCAAAGTCCACTGCATATCCTGC
TTTCAGCCTCAAGAGAGGCATTCTCAGTCAGGACTTCTGCCCTCTTCCTGCCTCCAGGATAGCCCTGGTGTTTCCCCGTGATGTAATTCC
CAGGGAAGATGGACGTTGATTGCTCCCAAGTCTCACTGGCATCCTTCCTTTGTTTTACTCAAGGGAACCTGTCTCTTCTCAGCTTTCTGT
GGTGTTCTGTGGTTCCTCCTGCTCAGCATATTTATAGACTCCAACTTTTCCTTCCCACTCTGGTCTAGTGATCCTCAGTTGTTGCCTGAA
TCATTGCAGAAGCCTCTCAGCCTGGCTCCCTCCTTCCTTCTTTGGCCCTCAACTGCATTTGGAATGTGCCTTTAGAGCCTGCGTTAGCAC
ATGTCACTTTTGCAAAAATCCTCCAGTGATTCTCATTTCACTCAGCATCACAGCCTGTGTCCTGCCATGGTCCATAAGATCTGCTCCCTC
CGTACTTCTTTGATGCTATGTTCAAGCTACTTGTCCTCCTCGTTCACATGATTGCATCGCTTGAGCTTCTTGCTACTCCTTGAACAGGCC

>102230_102230_10_ZNF511-PPAPDC1A_ZNF511_chr10_135125345_ENST00000368554_PPAPDC1A_chr10_122263330_ENST00000541332_length(amino acids)=376AA_BP=161
MQVADVPEKPRVPAFACQVAGCCQVFDALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQDMYQCLVEGCTEKF
KTSRDRKDHMVRMHLYPADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHSFTEFLDPFQRVIQPEEIW
LYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMH
CTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQVGCCVWQGPQSH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNF511-PPAPDC1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF511-PPAPDC1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF511-PPAPDC1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource