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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF532-GMPR (FusionGDB2 ID:102294)

Fusion Gene Summary for ZNF532-GMPR

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF532-GMPR
Fusion gene ID: 102294
HgeneTgene
Gene symbol

ZNF532

GMPR

Gene ID

55205

2766

Gene namezinc finger protein 532guanosine monophosphate reductase
Synonyms-GMPR 1|GMPR1
Cytomap

18q21.32

6p22.3

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 532GMP reductase 1guanine monophosphate reductaseguanosine 5'-monophosphate oxidoreductase 1guanosine monophosphate reductase 1
Modification date2020031320200313
UniProtAcc.

Q9P2T1

Ensembl transtripts involved in fusion geneENST00000336078, ENST00000589288, 
ENST00000591083, ENST00000591230, 
ENST00000591808, ENST00000588956, 
ENST00000544145, ENST00000259727, 
Fusion gene scores* DoF score12 X 11 X 10=13204 X 4 X 4=64
# samples 164
** MAII scorelog2(16/1320*10)=-3.04439411935845
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF532 [Title/Abstract] AND GMPR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF532(56621031)-GMPR(16247073), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ZNF532 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GMPR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-76-4929-01AZNF532chr18

56621031

+GMPRchr6

16247073

+


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Fusion Gene ORF analysis for ZNF532-GMPR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000336078ENST00000544145ZNF532chr18

56621031

+GMPRchr6

16247073

+
5CDS-intronENST00000589288ENST00000544145ZNF532chr18

56621031

+GMPRchr6

16247073

+
5CDS-intronENST00000591083ENST00000544145ZNF532chr18

56621031

+GMPRchr6

16247073

+
5CDS-intronENST00000591230ENST00000544145ZNF532chr18

56621031

+GMPRchr6

16247073

+
5CDS-intronENST00000591808ENST00000544145ZNF532chr18

56621031

+GMPRchr6

16247073

+
In-frameENST00000336078ENST00000259727ZNF532chr18

56621031

+GMPRchr6

16247073

+
In-frameENST00000589288ENST00000259727ZNF532chr18

56621031

+GMPRchr6

16247073

+
In-frameENST00000591083ENST00000259727ZNF532chr18

56621031

+GMPRchr6

16247073

+
In-frameENST00000591230ENST00000259727ZNF532chr18

56621031

+GMPRchr6

16247073

+
In-frameENST00000591808ENST00000259727ZNF532chr18

56621031

+GMPRchr6

16247073

+
intron-3CDSENST00000588956ENST00000259727ZNF532chr18

56621031

+GMPRchr6

16247073

+
intron-intronENST00000588956ENST00000544145ZNF532chr18

56621031

+GMPRchr6

16247073

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000336078ZNF532chr1856621031+ENST00000259727GMPRchr616247073+5240392676448761370
ENST00000591083ZNF532chr1856621031+ENST00000259727GMPRchr616247073+4810349633444461370
ENST00000589288ZNF532chr1856621031+ENST00000259727GMPRchr616247073+4665335118943011370
ENST00000591230ZNF532chr1856621031+ENST00000259727GMPRchr616247073+4818350434244541370
ENST00000591808ZNF532chr1856621031+ENST00000259727GMPRchr616247073+5353403987749891370

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000336078ENST00000259727ZNF532chr1856621031+GMPRchr616247073+0.0013395680.99866045
ENST00000591083ENST00000259727ZNF532chr1856621031+GMPRchr616247073+0.0012293130.99877065
ENST00000589288ENST00000259727ZNF532chr1856621031+GMPRchr616247073+0.0013668880.9986331
ENST00000591230ENST00000259727ZNF532chr1856621031+GMPRchr616247073+0.0011659690.9988341
ENST00000591808ENST00000259727ZNF532chr1856621031+GMPRchr616247073+0.0018972360.99810284

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Fusion Genomic Features for ZNF532-GMPR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNF532chr1856621031+GMPRchr616247072+2.71E-101
ZNF532chr1856621031+GMPRchr616247072+2.71E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZNF532-GMPR


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:56621031/chr6:16247073)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.GMPR

Q9P2T1

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (PubMed:12009299, PubMed:12669231, PubMed:16359702, PubMed:22037469). Plays a role in modulating cellular differentiation (PubMed:12669231). {ECO:0000255|HAMAP-Rule:MF_03195, ECO:0000269|PubMed:12009299, ECO:0000269|PubMed:12669231, ECO:0000269|PubMed:16359702, ECO:0000269|PubMed:22037469}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+8111025_104810501302.0Zinc fingerC2H2-type 8
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+811616_63510501302.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+811754_77910501302.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+811783_80510501302.0Zinc fingerC2H2-type 3
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+811842_86510501302.0Zinc fingerC2H2-type 4
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+811870_89310501302.0Zinc fingerC2H2-type 5
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+811905_92710501302.0Zinc fingerC2H2-type 6
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+811936_95910501302.0Zinc fingerC2H2-type 7
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+7101025_104810501302.0Zinc fingerC2H2-type 8
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+710616_63510501302.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+710754_77910501302.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+710783_80510501302.0Zinc fingerC2H2-type 3
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+710842_86510501302.0Zinc fingerC2H2-type 4
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+710870_89310501302.0Zinc fingerC2H2-type 5
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+710905_92710501302.0Zinc fingerC2H2-type 6
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+710936_95910501302.0Zinc fingerC2H2-type 7
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+7101025_104810501302.0Zinc fingerC2H2-type 8
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+710616_63510501302.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+710754_77910501302.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+710783_80510501302.0Zinc fingerC2H2-type 3
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+710842_86510501302.0Zinc fingerC2H2-type 4
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+710870_89310501302.0Zinc fingerC2H2-type 5
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+710905_92710501302.0Zinc fingerC2H2-type 6
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+710936_95910501302.0Zinc fingerC2H2-type 7
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+8111025_104810501302.0Zinc fingerC2H2-type 8
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+811616_63510501302.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+811754_77910501302.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+811783_80510501302.0Zinc fingerC2H2-type 3
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+811842_86510501302.0Zinc fingerC2H2-type 4
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+811870_89310501302.0Zinc fingerC2H2-type 5
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+811905_92710501302.0Zinc fingerC2H2-type 6
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+811936_95910501302.0Zinc fingerC2H2-type 7
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+7101025_104810501302.0Zinc fingerC2H2-type 8
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+710616_63510501302.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+710754_77910501302.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+710783_80510501302.0Zinc fingerC2H2-type 3
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+710842_86510501302.0Zinc fingerC2H2-type 4
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+710870_89310501302.0Zinc fingerC2H2-type 5
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+710905_92710501302.0Zinc fingerC2H2-type 6
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+710936_95910501302.0Zinc fingerC2H2-type 7
TgeneGMPRchr18:56621031chr6:16247073ENST0000025972709129_13129346.0Nucleotide bindingNADP
TgeneGMPRchr18:56621031chr6:16247073ENST0000025972709180_18129346.0Nucleotide bindingNADP
TgeneGMPRchr18:56621031chr6:16247073ENST000002597270926_2729346.0Nucleotide bindingNADP%3B shared with neighboring subunit
TgeneGMPRchr18:56621031chr6:16247073ENST0000025972709285_28629346.0Nucleotide bindingNADP
TgeneGMPRchr18:56621031chr6:16247073ENST0000025972709314_31729346.0Nucleotide bindingNADP%3B shared with neighboring subunit
TgeneGMPRchr18:56621031chr6:16247073ENST0000025972709219_22129346.0RegionGMP binding
TgeneGMPRchr18:56621031chr6:16247073ENST0000025972709242_24329346.0RegionGMP binding
TgeneGMPRchr18:56621031chr6:16247073ENST0000025972709268_27029346.0RegionGMP binding
TgeneGMPRchr18:56621031chr6:16247073ENST0000025972709286_29029346.0RegionGMP binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+8111055_107810501302.0Zinc fingerC2H2-type 9
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+8111085_111110501302.0Zinc fingerC2H2-type 10%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+8111203_122610501302.0Zinc fingerC2H2-type 11
HgeneZNF532chr18:56621031chr6:16247073ENST00000336078+8111264_128610501302.0Zinc fingerC2H2-type 12
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+7101055_107810501302.0Zinc fingerC2H2-type 9
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+7101085_111110501302.0Zinc fingerC2H2-type 10%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+7101203_122610501302.0Zinc fingerC2H2-type 11
HgeneZNF532chr18:56621031chr6:16247073ENST00000589288+7101264_128610501302.0Zinc fingerC2H2-type 12
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+7101055_107810501302.0Zinc fingerC2H2-type 9
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+7101085_111110501302.0Zinc fingerC2H2-type 10%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+7101203_122610501302.0Zinc fingerC2H2-type 11
HgeneZNF532chr18:56621031chr6:16247073ENST00000591083+7101264_128610501302.0Zinc fingerC2H2-type 12
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+8111055_107810501302.0Zinc fingerC2H2-type 9
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+8111085_111110501302.0Zinc fingerC2H2-type 10%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+8111203_122610501302.0Zinc fingerC2H2-type 11
HgeneZNF532chr18:56621031chr6:16247073ENST00000591230+8111264_128610501302.0Zinc fingerC2H2-type 12
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+7101055_107810501302.0Zinc fingerC2H2-type 9
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+7101085_111110501302.0Zinc fingerC2H2-type 10%3B degenerate
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+7101203_122610501302.0Zinc fingerC2H2-type 11
HgeneZNF532chr18:56621031chr6:16247073ENST00000591808+7101264_128610501302.0Zinc fingerC2H2-type 12


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Fusion Gene Sequence for ZNF532-GMPR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102294_102294_1_ZNF532-GMPR_ZNF532_chr18_56621031_ENST00000336078_GMPR_chr6_16247073_ENST00000259727_length(transcript)=5240nt_BP=3926nt
TCTCGCCCTTGCACGGGTCACGATTATACACCTTCGTGACCTTTAGCGGGCTTACATATGTATCTTTTTGTGTTCCGCAGGCTATGACCA
CCTGCTGTATGTACAATATGTGCTTGTTACATTTGTACACCATCTCCCTTCTAGAATTTAAAGACCTAGCTATTACATCTTGTTTACTCA
ATATCATTCCCCCATTAAGGAAAAAAAAAAACCTACATGAACTGAACATGCCATGTTTCAATCTGGCCCCAGTGGCTTTTTCTCTGAAAG
CAAACGTGTGTCTTTTACACCAGGGCTTTCTCCCCACCCCAGGGGGTGTCTTCCATCCTTTTGTGGCTCAGTTGAAGGCGAAAAGGGCTC
CAAACCACTAACTAACCAGAGGAGAGCCCCTTCTTCCACCTCCAGGGAGAATTTCAGATTTAATTTGTCCGAAGATAGCGTGCTCTCTTC
TTACTCATTTGCCATCATTACGAGGAAAACAAACCACCACCTTGGCTTCAAGATCCTGGGTAGAGGCTCACGGTCTTTTCAACCATCTTT
GGCGAGGCCTTGCTTCCTTCCACTCGAGGTATGTTCTGTCTTGTGCTTTTTCTTTTAGAAGCTACTAAAGGGTGTTGGGGATGCTTCTGA
CTATTATGAAGGCCAAAAGGCCTGTTGACTGGGGCTGCTTTTAACCCTTTCCTATTTGCTGAGAATGCAGCCGTGTGACAGTAACTGAAC
ATTGGTCTAAAGTCTTTCCAAAAGGTCAAGGTTCACAAGAACATCTGCTCAAATTAATGACCATGGGGGATATGAAGACCCCAGACTTTG
ATGACCTCCTGGCAGCATTTGACATCCCAGATATGGTCGATCCTAAAGCAGCTATTGAGTCTGGACACGATGACCATGAAAGCCACATGA
AGCAGAATGCTCACGGAGAGGATGACTCCCACGCACCATCATCTTCTGATGTGGGTGTCAGCGTTATCGTCAAGAATGTTCGGAACATTG
ACTCTTCCGAGGGCGGGGAGAAAGACGGCCACAACCCCACTGGCAATGGCTTACATAATGGGTTTCTCACAGCATCCTCCCTTGACAGTT
ACAGTAAAGATGGAGCAAAGTCCTTGAAAGGAGATGTGCCTGCCTCTGAGGTGACACTGAAAGACTCGACATTCAGCCAGTTTAGCCCGA
TCTCCAGTGCTGAAGAGTTTGATGACGACGAGAAGATTGAGGTGGATGACCCCCCTGACAAGGAGGACATGCGATCAAGCTTCAGGTCGA
ATGTGTTGACGGGGTCGGCTCCCCAGCAGGACTACGATAAGCTGAAGGCACTCGGAGGGGAAAACTCCAGCAAAACTGGACTCTCTACGT
CAGGCAATGTGGAGAAAAACAAAGCTGTTAAGAGAGAAACAGAAGCCAGTTCTATAAACCTGAGTGTTTATGAACCTTTTAAAGTCAGAA
AAGCAGAGGATAAATTGAAGGAAAGCTCTGACAAGGTGCTGGAAAACAGAGTCCTAGATGGGAAGCTGAGCTCCGAGAAGAATGACACCA
GCCTCCCCAGCGTTGCGCCATCAAAGACAAAGTCGTCCTCCAAGCTCTCGTCCTGCATCGCTGCCATCGCGGCTCTCAGCGCTAAAAAGG
CGGCTTCAGACTCCTGCAAAGAACCAGTGGCCAATTCGAGGGAATCCTCCCCGTTACCAAAAGAAGTAAATGACAGTCCGAGAGCCGCTG
ACAAGTCTCCTGAATCCCAGAATCTCATCGACGGGACCAAAAAACCATCCCTGAAGCAACCGGATAGTCCCAGAAGCATCTCAAGTGAGA
ACAGCAGCAAAGGATCCCCGTCCTCTCCCGCAGGGTCCACACCAGCAATCCCCAAAGTCCGCATAAAAACCATTAAGACATCTTCTGGGG
AAATCAAGAGAACAGTGACCAGGGTATTGCCAGAAGTGGATCTTGACTCTGGAAAGAAACCTTCCGAGCAGACAGCGTCCGTGATGGCCT
CTGTGACATCCCTTCTGTCGTCTCCAGCATCAGCCGCCGTCCTTTCCTCTCCCCCCAGGGCGCCTCTCCAGTCTGCGGTCGTGACCAATG
CAGTTTCCCCTGCAGAGCTCACCCCCAAACAGGTCACAATCAAGCCTGTGGCTACTGCTTTCCTCCCAGTGTCTGCTGTGAAGACGGCAG
GATCCCAAGTCATTAATTTGAAGCTCGCTAACAACACCACGGTGAAAGCCACGGTCATATCTGCTGCCTCTGTCCAGAGTGCCAGCAGCG
CCATCATTAAAGCTGCCAACGCCATCCAGCAGCAAACTGTCGTGGTGCCGGCATCCAGCCTGGCCAATGCCAAACTCGTGCCAAAGACTG
TGCACCTTGCCAACCTTAACCTTTTGCCTCAGGGTGCCCAGGCCACCTCTGAACTCCGCCAAGTGCTAACCAAACCTCAGCAACAAATAA
AGCAGGCAATAATCAATGCAGCAGCCTCGCAACCCCCCAAAAAGGTGTCTCGAGTCCAGGTGGTGTCGTCCTTGCAGAGTTCTGTGGTGG
AAGCTTTCAACAAGGTGCTGAGCAGTGTCAATCCAGTCCCTGTTTACATCCCAAACCTCAGTCCTCCCGCCAATGCAGGGATCACGTTAC
CGACGCGTGGGTACAAGTGCTTGGAGTGTGGGGACTCCTTTGCACTTGAAAAGAGTCTGACCCAGCACTACGACAGACGGAGCGTGCGCA
TCGAAGTAACGTGCAACCATTGTACAAAGAACCTCGTTTTTTACAACAAATGCAGCCTCCTTTCCCATGCCCGTGGGCATAAGGAGAAAG
GGGTGGTAATGCAATGCTCCCACTTAATTTTAAAGCCAGTCCCAGCAGATCAAATGATAGTTTCTCCGTCAAGCAATACTTCCACTTCAA
CTTCCACTCTTCAGAGCCCTGTGGGAGCTGGCACACACACTGTCACAAAAATTCAGTCTGGCATAACTGGGACAGTCATATCGGCTCCTT
CAAGCACTCCCATCACCCCAGCCATGCCCCTAGATGAAGACCCCTCCAAACTGTGTAGACATAGTCTAAAATGTTTGGAGTGTAATGAAG
TCTTCCAGGACGAGACATCACTGGCTACACATTTCCAGCAGGCTGCAGATACGAGTGGACAAAAGACTTGCACTATCTGCCAGATGCTGC
TTCCTAACCAGTGCAGTTATGCATCACACCAGAGAATCCATCAGCACAAATCTCCCTACACCTGCCCTGAGTGTGGGGCCATCTGCAGGT
CGGTGCACTTCCAGACCCACGTCACCAAGAACTGTCTGCACTACACGAGGAGAGTTGGTTTTCGATGTGTGCATTGCAATGTTGTGTACT
CTGATGTGGCTGCTCTGAAGTCTCACATTCAAGGTTCTCACTGTGAAGTCTTCTACAAGTGTCCTATTTGTCCAATGGCGTTTAAGTCTG
CCCCAAGCACACATTCCCACGCCTACACACAGCATCCTGGCATCAAGATAGGAGAACCAAAAATAATATATAAGTGTTCCATGTGCGACA
CTGTGTTCACCCTGCAAACCTTGCTGTATCGCCACTTTGACCAACACATTGAAAACCAGAAGGTGTCTGTTTTCAAGTGTCCAGACTGTT
CTCTTTTATATGCACAGAAGCAACTTATGATGGACCATATCAAGTCTATGCATGGAACATTGAAAAGTATTGAAGGGCCTCCAAACTTGG
GTATAAACTTGCCTTTGAGCATTAAGCCTGCAACTCAAAATTCAGCAAATCAGAACAAAGAGGACACCAAATCCATGAATGGGAAAGAGA
AATTGGAAAAGAAATCTCCATCTCCTGTGAAAAAATCAATGGAAACCAAGAAAGTGGCCAGTCCTGGGTGGACGTGTTGGGAGTGTGACT
GCCTGTTCATGCAGAGAGATGTGTACATATCCCACGTGAGGAAGGAGCACGGGAAGGTGGATCTTGAACGCACCTTCACGTTTCGAAATT
CAAAGCAGACCTACTCAGGGATTCCCATCATCGTGGCCAACATGGACACTGTGGGCACGTTTGAGATGGCAGCCGTGATGTCACAGCACT
CCATGTTTACAGCAATTCATAAGCATTACTCCCTGGATGACTGGAAGCTCTTTGCCACAAATCACCCAGAATGCCTGCAGAATGTAGCCG
TGAGTTCAGGCAGTGGGCAGAATGATCTGGAAAAGATGACCAGCATCCTGGAAGCTGTGCCACAGGTTAAGTTTATTTGCCTGGATGTGG
CCAATGGGTATTCAGAACATTTTGTGGAATTCGTGAAACTTGTCCGTGCCAAATTTCCTGAACACACCATTATGGCAGGGAACGTGGTGA
CAGGAGAAATGGTAGAAGAGCTTATTCTTTCCGGAGCAGATATCATCAAAGTGGGAGTTGGACCAGGTTCTGTGTGCACCACCCGCACCA
AGACGGGAGTGGGGTACCCCCAGCTGAGTGCCGTCATTGAGTGTGCCGACTCTGCCCATGGCCTGAAGGGCCACATCATCTCTGATGGAG
GCTGTACGTGTCCAGGGGATGTCGCCAAAGCCTTTGGAGCTGGAGCAGATTTTGTCATGCTGGGAGGAATGTTTTCGGGTCATACGGAGT
GTGCTGGAGAAGTGTTTGAGAGGAACGGACGGAAGCTCAAGCTCTTCTACGGGATGAGCTCTGACACCGCCATGAACAAGCACGCAGGAG
GAGTTGCTGAGTACAGAGCCTCTGAGGGTAAGACTGTGGAAGTTCCTTACAAAGGAGATGTGGAAAACACTATCCTGGATATTCTCGGGG
GACTGAGGTCCACGTGCACCTACGTGGGGGCCGCCAAACTCAAGGAGCTCAGCAGGAGGGCAACATTCATCCGGGTGACCCAGCAGCACA
ACACCGTGTTCAGCTAACCCTGGGGACAAAGCAGCGTCTGGCTCGAGTGGAAGCGTCCAAACCTGCTTTTCCCATCTCCCCCCAAGTCTG
TTCCGTCAGAGCTTCTGGCTGCTCCTGAATGGTGGAATGCTGTGTCCTCTCTTCTGTCTCCTGCTGCCTGGAGGCTTCGGGGCTCTCCCG
CCTGCCTTCTCGGGGCCCAGACGCAAGGCACCGATTGGGCCAACATCAGAGCCCTGCTGCCCAGAACTCATAACCTCATTGTTCAAACCA
ACACTTGCACCTTTCTCTTTTTCTCTTTCTCTCTCCCTTTCTTTGTTTTTCTTTCTTTTTTAAAAGAAGATGGTTTCACTTTAATATAAT

>102294_102294_1_ZNF532-GMPR_ZNF532_chr18_56621031_ENST00000336078_GMPR_chr6_16247073_ENST00000259727_length(amino acids)=1370AA_BP=1054
MLKLMTMGDMKTPDFDDLLAAFDIPDMVDPKAAIESGHDDHESHMKQNAHGEDDSHAPSSSDVGVSVIVKNVRNIDSSEGGEKDGHNPTG
NGLHNGFLTASSLDSYSKDGAKSLKGDVPASEVTLKDSTFSQFSPISSAEEFDDDEKIEVDDPPDKEDMRSSFRSNVLTGSAPQQDYDKL
KALGGENSSKTGLSTSGNVEKNKAVKRETEASSINLSVYEPFKVRKAEDKLKESSDKVLENRVLDGKLSSEKNDTSLPSVAPSKTKSSSK
LSSCIAAIAALSAKKAASDSCKEPVANSRESSPLPKEVNDSPRAADKSPESQNLIDGTKKPSLKQPDSPRSISSENSSKGSPSSPAGSTP
AIPKVRIKTIKTSSGEIKRTVTRVLPEVDLDSGKKPSEQTASVMASVTSLLSSPASAAVLSSPPRAPLQSAVVTNAVSPAELTPKQVTIK
PVATAFLPVSAVKTAGSQVINLKLANNTTVKATVISAASVQSASSAIIKAANAIQQQTVVVPASSLANAKLVPKTVHLANLNLLPQGAQA
TSELRQVLTKPQQQIKQAIINAAASQPPKKVSRVQVVSSLQSSVVEAFNKVLSSVNPVPVYIPNLSPPANAGITLPTRGYKCLECGDSFA
LEKSLTQHYDRRSVRIEVTCNHCTKNLVFYNKCSLLSHARGHKEKGVVMQCSHLILKPVPADQMIVSPSSNTSTSTSTLQSPVGAGTHTV
TKIQSGITGTVISAPSSTPITPAMPLDEDPSKLCRHSLKCLECNEVFQDETSLATHFQQAADTSGQKTCTICQMLLPNQCSYASHQRIHQ
HKSPYTCPECGAICRSVHFQTHVTKNCLHYTRRVGFRCVHCNVVYSDVAALKSHIQGSHCEVFYKCPICPMAFKSAPSTHSHAYTQHPGI
KIGEPKIIYKCSMCDTVFTLQTLLYRHFDQHIENQKVSVFKCPDCSLLYAQKQLMMDHIKSMHGTLKSIEGPPNLGINLPLSIKPATQNS
ANQNKEDTKSMNGKEKLEKKSPSPVKKSMETKKVASPGWTCWECDCLFMQRDVYISHVRKEHGKVDLERTFTFRNSKQTYSGIPIIVANM
DTVGTFEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLV
RAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAG
ADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLK

--------------------------------------------------------------
>102294_102294_2_ZNF532-GMPR_ZNF532_chr18_56621031_ENST00000589288_GMPR_chr6_16247073_ENST00000259727_length(transcript)=4665nt_BP=3351nt
CGCCGCCGCCGCCGCTCCGACGACAGCAGCAGCAGCCACAGCAGCAGCCGCCGGCGGCGCCGCGCTGAACAAAGGCCTGTTGACTGGGGC
TGCTTTTAACCCTTTCCTATTTGCTGAGAATGCAGCCGTGTGACAGTAACTGAACATTGGTCTAAAGTCTTTCCAAAAGGTCAAGGTTCA
CAAGAACATCTGCTCAAATTAATGACCATGGGGGATATGAAGACCCCAGACTTTGATGACCTCCTGGCAGCATTTGACATCCCAGATATG
GTCGATCCTAAAGCAGCTATTGAGTCTGGACACGATGACCATGAAAGCCACATGAAGCAGAATGCTCACGGAGAGGATGACTCCCACGCA
CCATCATCTTCTGATGTGGGTGTCAGCGTTATCGTCAAGAATGTTCGGAACATTGACTCTTCCGAGGGCGGGGAGAAAGACGGCCACAAC
CCCACTGGCAATGGCTTACATAATGGGTTTCTCACAGCATCCTCCCTTGACAGTTACAGTAAAGATGGAGCAAAGTCCTTGAAAGGAGAT
GTGCCTGCCTCTGAGGTGACACTGAAAGACTCGACATTCAGCCAGTTTAGCCCGATCTCCAGTGCTGAAGAGTTTGATGACGACGAGAAG
ATTGAGGTGGATGACCCCCCTGACAAGGAGGACATGCGATCAAGCTTCAGGTCGAATGTGTTGACGGGGTCGGCTCCCCAGCAGGACTAC
GATAAGCTGAAGGCACTCGGAGGGGAAAACTCCAGCAAAACTGGACTCTCTACGTCAGGCAATGTGGAGAAAAACAAAGCTGTTAAGAGA
GAAACAGAAGCCAGTTCTATAAACCTGAGTGTTTATGAACCTTTTAAAGTCAGAAAAGCAGAGGATAAATTGAAGGAAAGCTCTGACAAG
GTGCTGGAAAACAGAGTCCTAGATGGGAAGCTGAGCTCCGAGAAGAATGACACCAGCCTCCCCAGCGTTGCGCCATCAAAGACAAAGTCG
TCCTCCAAGCTCTCGTCCTGCATCGCTGCCATCGCGGCTCTCAGCGCTAAAAAGGCGGCTTCAGACTCCTGCAAAGAACCAGTGGCCAAT
TCGAGGGAATCCTCCCCGTTACCAAAAGAAGTAAATGACAGTCCGAGAGCCGCTGACAAGTCTCCTGAATCCCAGAATCTCATCGACGGG
ACCAAAAAACCATCCCTGAAGCAACCGGATAGTCCCAGAAGCATCTCAAGTGAGAACAGCAGCAAAGGATCCCCGTCCTCTCCCGCAGGG
TCCACACCAGCAATCCCCAAAGTCCGCATAAAAACCATTAAGACATCTTCTGGGGAAATCAAGAGAACAGTGACCAGGGTATTGCCAGAA
GTGGATCTTGACTCTGGAAAGAAACCTTCCGAGCAGACAGCGTCCGTGATGGCCTCTGTGACATCCCTTCTGTCGTCTCCAGCATCAGCC
GCCGTCCTTTCCTCTCCCCCCAGGGCGCCTCTCCAGTCTGCGGTCGTGACCAATGCAGTTTCCCCTGCAGAGCTCACCCCCAAACAGGTC
ACAATCAAGCCTGTGGCTACTGCTTTCCTCCCAGTGTCTGCTGTGAAGACGGCAGGATCCCAAGTCATTAATTTGAAGCTCGCTAACAAC
ACCACGGTGAAAGCCACGGTCATATCTGCTGCCTCTGTCCAGAGTGCCAGCAGCGCCATCATTAAAGCTGCCAACGCCATCCAGCAGCAA
ACTGTCGTGGTGCCGGCATCCAGCCTGGCCAATGCCAAACTCGTGCCAAAGACTGTGCACCTTGCCAACCTTAACCTTTTGCCTCAGGGT
GCCCAGGCCACCTCTGAACTCCGCCAAGTGCTAACCAAACCTCAGCAACAAATAAAGCAGGCAATAATCAATGCAGCAGCCTCGCAACCC
CCCAAAAAGGTGTCTCGAGTCCAGGTGGTGTCGTCCTTGCAGAGTTCTGTGGTGGAAGCTTTCAACAAGGTGCTGAGCAGTGTCAATCCA
GTCCCTGTTTACATCCCAAACCTCAGTCCTCCCGCCAATGCAGGGATCACGTTACCGACGCGTGGGTACAAGTGCTTGGAGTGTGGGGAC
TCCTTTGCACTTGAAAAGAGTCTGACCCAGCACTACGACAGACGGAGCGTGCGCATCGAAGTAACGTGCAACCATTGTACAAAGAACCTC
GTTTTTTACAACAAATGCAGCCTCCTTTCCCATGCCCGTGGGCATAAGGAGAAAGGGGTGGTAATGCAATGCTCCCACTTAATTTTAAAG
CCAGTCCCAGCAGATCAAATGATAGTTTCTCCGTCAAGCAATACTTCCACTTCAACTTCCACTCTTCAGAGCCCTGTGGGAGCTGGCACA
CACACTGTCACAAAAATTCAGTCTGGCATAACTGGGACAGTCATATCGGCTCCTTCAAGCACTCCCATCACCCCAGCCATGCCCCTAGAT
GAAGACCCCTCCAAACTGTGTAGACATAGTCTAAAATGTTTGGAGTGTAATGAAGTCTTCCAGGACGAGACATCACTGGCTACACATTTC
CAGCAGGCTGCAGATACGAGTGGACAAAAGACTTGCACTATCTGCCAGATGCTGCTTCCTAACCAGTGCAGTTATGCATCACACCAGAGA
ATCCATCAGCACAAATCTCCCTACACCTGCCCTGAGTGTGGGGCCATCTGCAGGTCGGTGCACTTCCAGACCCACGTCACCAAGAACTGT
CTGCACTACACGAGGAGAGTTGGTTTTCGATGTGTGCATTGCAATGTTGTGTACTCTGATGTGGCTGCTCTGAAGTCTCACATTCAAGGT
TCTCACTGTGAAGTCTTCTACAAGTGTCCTATTTGTCCAATGGCGTTTAAGTCTGCCCCAAGCACACATTCCCACGCCTACACACAGCAT
CCTGGCATCAAGATAGGAGAACCAAAAATAATATATAAGTGTTCCATGTGCGACACTGTGTTCACCCTGCAAACCTTGCTGTATCGCCAC
TTTGACCAACACATTGAAAACCAGAAGGTGTCTGTTTTCAAGTGTCCAGACTGTTCTCTTTTATATGCACAGAAGCAACTTATGATGGAC
CATATCAAGTCTATGCATGGAACATTGAAAAGTATTGAAGGGCCTCCAAACTTGGGTATAAACTTGCCTTTGAGCATTAAGCCTGCAACT
CAAAATTCAGCAAATCAGAACAAAGAGGACACCAAATCCATGAATGGGAAAGAGAAATTGGAAAAGAAATCTCCATCTCCTGTGAAAAAA
TCAATGGAAACCAAGAAAGTGGCCAGTCCTGGGTGGACGTGTTGGGAGTGTGACTGCCTGTTCATGCAGAGAGATGTGTACATATCCCAC
GTGAGGAAGGAGCACGGGAAGGTGGATCTTGAACGCACCTTCACGTTTCGAAATTCAAAGCAGACCTACTCAGGGATTCCCATCATCGTG
GCCAACATGGACACTGTGGGCACGTTTGAGATGGCAGCCGTGATGTCACAGCACTCCATGTTTACAGCAATTCATAAGCATTACTCCCTG
GATGACTGGAAGCTCTTTGCCACAAATCACCCAGAATGCCTGCAGAATGTAGCCGTGAGTTCAGGCAGTGGGCAGAATGATCTGGAAAAG
ATGACCAGCATCCTGGAAGCTGTGCCACAGGTTAAGTTTATTTGCCTGGATGTGGCCAATGGGTATTCAGAACATTTTGTGGAATTCGTG
AAACTTGTCCGTGCCAAATTTCCTGAACACACCATTATGGCAGGGAACGTGGTGACAGGAGAAATGGTAGAAGAGCTTATTCTTTCCGGA
GCAGATATCATCAAAGTGGGAGTTGGACCAGGTTCTGTGTGCACCACCCGCACCAAGACGGGAGTGGGGTACCCCCAGCTGAGTGCCGTC
ATTGAGTGTGCCGACTCTGCCCATGGCCTGAAGGGCCACATCATCTCTGATGGAGGCTGTACGTGTCCAGGGGATGTCGCCAAAGCCTTT
GGAGCTGGAGCAGATTTTGTCATGCTGGGAGGAATGTTTTCGGGTCATACGGAGTGTGCTGGAGAAGTGTTTGAGAGGAACGGACGGAAG
CTCAAGCTCTTCTACGGGATGAGCTCTGACACCGCCATGAACAAGCACGCAGGAGGAGTTGCTGAGTACAGAGCCTCTGAGGGTAAGACT
GTGGAAGTTCCTTACAAAGGAGATGTGGAAAACACTATCCTGGATATTCTCGGGGGACTGAGGTCCACGTGCACCTACGTGGGGGCCGCC
AAACTCAAGGAGCTCAGCAGGAGGGCAACATTCATCCGGGTGACCCAGCAGCACAACACCGTGTTCAGCTAACCCTGGGGACAAAGCAGC
GTCTGGCTCGAGTGGAAGCGTCCAAACCTGCTTTTCCCATCTCCCCCCAAGTCTGTTCCGTCAGAGCTTCTGGCTGCTCCTGAATGGTGG
AATGCTGTGTCCTCTCTTCTGTCTCCTGCTGCCTGGAGGCTTCGGGGCTCTCCCGCCTGCCTTCTCGGGGCCCAGACGCAAGGCACCGAT
TGGGCCAACATCAGAGCCCTGCTGCCCAGAACTCATAACCTCATTGTTCAAACCAACACTTGCACCTTTCTCTTTTTCTCTTTCTCTCTC

>102294_102294_2_ZNF532-GMPR_ZNF532_chr18_56621031_ENST00000589288_GMPR_chr6_16247073_ENST00000259727_length(amino acids)=1370AA_BP=1054
MLKLMTMGDMKTPDFDDLLAAFDIPDMVDPKAAIESGHDDHESHMKQNAHGEDDSHAPSSSDVGVSVIVKNVRNIDSSEGGEKDGHNPTG
NGLHNGFLTASSLDSYSKDGAKSLKGDVPASEVTLKDSTFSQFSPISSAEEFDDDEKIEVDDPPDKEDMRSSFRSNVLTGSAPQQDYDKL
KALGGENSSKTGLSTSGNVEKNKAVKRETEASSINLSVYEPFKVRKAEDKLKESSDKVLENRVLDGKLSSEKNDTSLPSVAPSKTKSSSK
LSSCIAAIAALSAKKAASDSCKEPVANSRESSPLPKEVNDSPRAADKSPESQNLIDGTKKPSLKQPDSPRSISSENSSKGSPSSPAGSTP
AIPKVRIKTIKTSSGEIKRTVTRVLPEVDLDSGKKPSEQTASVMASVTSLLSSPASAAVLSSPPRAPLQSAVVTNAVSPAELTPKQVTIK
PVATAFLPVSAVKTAGSQVINLKLANNTTVKATVISAASVQSASSAIIKAANAIQQQTVVVPASSLANAKLVPKTVHLANLNLLPQGAQA
TSELRQVLTKPQQQIKQAIINAAASQPPKKVSRVQVVSSLQSSVVEAFNKVLSSVNPVPVYIPNLSPPANAGITLPTRGYKCLECGDSFA
LEKSLTQHYDRRSVRIEVTCNHCTKNLVFYNKCSLLSHARGHKEKGVVMQCSHLILKPVPADQMIVSPSSNTSTSTSTLQSPVGAGTHTV
TKIQSGITGTVISAPSSTPITPAMPLDEDPSKLCRHSLKCLECNEVFQDETSLATHFQQAADTSGQKTCTICQMLLPNQCSYASHQRIHQ
HKSPYTCPECGAICRSVHFQTHVTKNCLHYTRRVGFRCVHCNVVYSDVAALKSHIQGSHCEVFYKCPICPMAFKSAPSTHSHAYTQHPGI
KIGEPKIIYKCSMCDTVFTLQTLLYRHFDQHIENQKVSVFKCPDCSLLYAQKQLMMDHIKSMHGTLKSIEGPPNLGINLPLSIKPATQNS
ANQNKEDTKSMNGKEKLEKKSPSPVKKSMETKKVASPGWTCWECDCLFMQRDVYISHVRKEHGKVDLERTFTFRNSKQTYSGIPIIVANM
DTVGTFEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLV
RAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAG
ADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLK

--------------------------------------------------------------
>102294_102294_3_ZNF532-GMPR_ZNF532_chr18_56621031_ENST00000591083_GMPR_chr6_16247073_ENST00000259727_length(transcript)=4810nt_BP=3496nt
CGAAAAGGGCTCCAAACCACTAACTAACCAGAGGAGAGCCCCTTCTTCCACCTCCAGGGAGAATTTCAGATTTAATTTGTCCGAAGATAG
CGTGCTCTCTTCTTACTCATTTGCCATCATTACGAGGAAAACAAACCACCACCTTGGCTTCAAGATCCTGGGTAGAGGCTCACGGTCTTT
TCAACCATCTTTGGCGAGGCCTTGCTTCCTTCCACTCGAGCCTGTTGACTGGGGCTGCTTTTAACCCTTTCCTATTTGCTGAGAATGCAG
CCGTGTGACAGTAACTGAACATTGGTCTAAAGTCTTTCCAAAAGGTCAAGGTTCACAAGAACATCTGCTCAAATTAATGACCATGGGGGA
TATGAAGACCCCAGACTTTGATGACCTCCTGGCAGCATTTGACATCCCAGATATGGTCGATCCTAAAGCAGCTATTGAGTCTGGACACGA
TGACCATGAAAGCCACATGAAGCAGAATGCTCACGGAGAGGATGACTCCCACGCACCATCATCTTCTGATGTGGGTGTCAGCGTTATCGT
CAAGAATGTTCGGAACATTGACTCTTCCGAGGGCGGGGAGAAAGACGGCCACAACCCCACTGGCAATGGCTTACATAATGGGTTTCTCAC
AGCATCCTCCCTTGACAGTTACAGTAAAGATGGAGCAAAGTCCTTGAAAGGAGATGTGCCTGCCTCTGAGGTGACACTGAAAGACTCGAC
ATTCAGCCAGTTTAGCCCGATCTCCAGTGCTGAAGAGTTTGATGACGACGAGAAGATTGAGGTGGATGACCCCCCTGACAAGGAGGACAT
GCGATCAAGCTTCAGGTCGAATGTGTTGACGGGGTCGGCTCCCCAGCAGGACTACGATAAGCTGAAGGCACTCGGAGGGGAAAACTCCAG
CAAAACTGGACTCTCTACGTCAGGCAATGTGGAGAAAAACAAAGCTGTTAAGAGAGAAACAGAAGCCAGTTCTATAAACCTGAGTGTTTA
TGAACCTTTTAAAGTCAGAAAAGCAGAGGATAAATTGAAGGAAAGCTCTGACAAGGTGCTGGAAAACAGAGTCCTAGATGGGAAGCTGAG
CTCCGAGAAGAATGACACCAGCCTCCCCAGCGTTGCGCCATCAAAGACAAAGTCGTCCTCCAAGCTCTCGTCCTGCATCGCTGCCATCGC
GGCTCTCAGCGCTAAAAAGGCGGCTTCAGACTCCTGCAAAGAACCAGTGGCCAATTCGAGGGAATCCTCCCCGTTACCAAAAGAAGTAAA
TGACAGTCCGAGAGCCGCTGACAAGTCTCCTGAATCCCAGAATCTCATCGACGGGACCAAAAAACCATCCCTGAAGCAACCGGATAGTCC
CAGAAGCATCTCAAGTGAGAACAGCAGCAAAGGATCCCCGTCCTCTCCCGCAGGGTCCACACCAGCAATCCCCAAAGTCCGCATAAAAAC
CATTAAGACATCTTCTGGGGAAATCAAGAGAACAGTGACCAGGGTATTGCCAGAAGTGGATCTTGACTCTGGAAAGAAACCTTCCGAGCA
GACAGCGTCCGTGATGGCCTCTGTGACATCCCTTCTGTCGTCTCCAGCATCAGCCGCCGTCCTTTCCTCTCCCCCCAGGGCGCCTCTCCA
GTCTGCGGTCGTGACCAATGCAGTTTCCCCTGCAGAGCTCACCCCCAAACAGGTCACAATCAAGCCTGTGGCTACTGCTTTCCTCCCAGT
GTCTGCTGTGAAGACGGCAGGATCCCAAGTCATTAATTTGAAGCTCGCTAACAACACCACGGTGAAAGCCACGGTCATATCTGCTGCCTC
TGTCCAGAGTGCCAGCAGCGCCATCATTAAAGCTGCCAACGCCATCCAGCAGCAAACTGTCGTGGTGCCGGCATCCAGCCTGGCCAATGC
CAAACTCGTGCCAAAGACTGTGCACCTTGCCAACCTTAACCTTTTGCCTCAGGGTGCCCAGGCCACCTCTGAACTCCGCCAAGTGCTAAC
CAAACCTCAGCAACAAATAAAGCAGGCAATAATCAATGCAGCAGCCTCGCAACCCCCCAAAAAGGTGTCTCGAGTCCAGGTGGTGTCGTC
CTTGCAGAGTTCTGTGGTGGAAGCTTTCAACAAGGTGCTGAGCAGTGTCAATCCAGTCCCTGTTTACATCCCAAACCTCAGTCCTCCCGC
CAATGCAGGGATCACGTTACCGACGCGTGGGTACAAGTGCTTGGAGTGTGGGGACTCCTTTGCACTTGAAAAGAGTCTGACCCAGCACTA
CGACAGACGGAGCGTGCGCATCGAAGTAACGTGCAACCATTGTACAAAGAACCTCGTTTTTTACAACAAATGCAGCCTCCTTTCCCATGC
CCGTGGGCATAAGGAGAAAGGGGTGGTAATGCAATGCTCCCACTTAATTTTAAAGCCAGTCCCAGCAGATCAAATGATAGTTTCTCCGTC
AAGCAATACTTCCACTTCAACTTCCACTCTTCAGAGCCCTGTGGGAGCTGGCACACACACTGTCACAAAAATTCAGTCTGGCATAACTGG
GACAGTCATATCGGCTCCTTCAAGCACTCCCATCACCCCAGCCATGCCCCTAGATGAAGACCCCTCCAAACTGTGTAGACATAGTCTAAA
ATGTTTGGAGTGTAATGAAGTCTTCCAGGACGAGACATCACTGGCTACACATTTCCAGCAGGCTGCAGATACGAGTGGACAAAAGACTTG
CACTATCTGCCAGATGCTGCTTCCTAACCAGTGCAGTTATGCATCACACCAGAGAATCCATCAGCACAAATCTCCCTACACCTGCCCTGA
GTGTGGGGCCATCTGCAGGTCGGTGCACTTCCAGACCCACGTCACCAAGAACTGTCTGCACTACACGAGGAGAGTTGGTTTTCGATGTGT
GCATTGCAATGTTGTGTACTCTGATGTGGCTGCTCTGAAGTCTCACATTCAAGGTTCTCACTGTGAAGTCTTCTACAAGTGTCCTATTTG
TCCAATGGCGTTTAAGTCTGCCCCAAGCACACATTCCCACGCCTACACACAGCATCCTGGCATCAAGATAGGAGAACCAAAAATAATATA
TAAGTGTTCCATGTGCGACACTGTGTTCACCCTGCAAACCTTGCTGTATCGCCACTTTGACCAACACATTGAAAACCAGAAGGTGTCTGT
TTTCAAGTGTCCAGACTGTTCTCTTTTATATGCACAGAAGCAACTTATGATGGACCATATCAAGTCTATGCATGGAACATTGAAAAGTAT
TGAAGGGCCTCCAAACTTGGGTATAAACTTGCCTTTGAGCATTAAGCCTGCAACTCAAAATTCAGCAAATCAGAACAAAGAGGACACCAA
ATCCATGAATGGGAAAGAGAAATTGGAAAAGAAATCTCCATCTCCTGTGAAAAAATCAATGGAAACCAAGAAAGTGGCCAGTCCTGGGTG
GACGTGTTGGGAGTGTGACTGCCTGTTCATGCAGAGAGATGTGTACATATCCCACGTGAGGAAGGAGCACGGGAAGGTGGATCTTGAACG
CACCTTCACGTTTCGAAATTCAAAGCAGACCTACTCAGGGATTCCCATCATCGTGGCCAACATGGACACTGTGGGCACGTTTGAGATGGC
AGCCGTGATGTCACAGCACTCCATGTTTACAGCAATTCATAAGCATTACTCCCTGGATGACTGGAAGCTCTTTGCCACAAATCACCCAGA
ATGCCTGCAGAATGTAGCCGTGAGTTCAGGCAGTGGGCAGAATGATCTGGAAAAGATGACCAGCATCCTGGAAGCTGTGCCACAGGTTAA
GTTTATTTGCCTGGATGTGGCCAATGGGTATTCAGAACATTTTGTGGAATTCGTGAAACTTGTCCGTGCCAAATTTCCTGAACACACCAT
TATGGCAGGGAACGTGGTGACAGGAGAAATGGTAGAAGAGCTTATTCTTTCCGGAGCAGATATCATCAAAGTGGGAGTTGGACCAGGTTC
TGTGTGCACCACCCGCACCAAGACGGGAGTGGGGTACCCCCAGCTGAGTGCCGTCATTGAGTGTGCCGACTCTGCCCATGGCCTGAAGGG
CCACATCATCTCTGATGGAGGCTGTACGTGTCCAGGGGATGTCGCCAAAGCCTTTGGAGCTGGAGCAGATTTTGTCATGCTGGGAGGAAT
GTTTTCGGGTCATACGGAGTGTGCTGGAGAAGTGTTTGAGAGGAACGGACGGAAGCTCAAGCTCTTCTACGGGATGAGCTCTGACACCGC
CATGAACAAGCACGCAGGAGGAGTTGCTGAGTACAGAGCCTCTGAGGGTAAGACTGTGGAAGTTCCTTACAAAGGAGATGTGGAAAACAC
TATCCTGGATATTCTCGGGGGACTGAGGTCCACGTGCACCTACGTGGGGGCCGCCAAACTCAAGGAGCTCAGCAGGAGGGCAACATTCAT
CCGGGTGACCCAGCAGCACAACACCGTGTTCAGCTAACCCTGGGGACAAAGCAGCGTCTGGCTCGAGTGGAAGCGTCCAAACCTGCTTTT
CCCATCTCCCCCCAAGTCTGTTCCGTCAGAGCTTCTGGCTGCTCCTGAATGGTGGAATGCTGTGTCCTCTCTTCTGTCTCCTGCTGCCTG
GAGGCTTCGGGGCTCTCCCGCCTGCCTTCTCGGGGCCCAGACGCAAGGCACCGATTGGGCCAACATCAGAGCCCTGCTGCCCAGAACTCA
TAACCTCATTGTTCAAACCAACACTTGCACCTTTCTCTTTTTCTCTTTCTCTCTCCCTTTCTTTGTTTTTCTTTCTTTTTTAAAAGAAGA

>102294_102294_3_ZNF532-GMPR_ZNF532_chr18_56621031_ENST00000591083_GMPR_chr6_16247073_ENST00000259727_length(amino acids)=1370AA_BP=1054
MLKLMTMGDMKTPDFDDLLAAFDIPDMVDPKAAIESGHDDHESHMKQNAHGEDDSHAPSSSDVGVSVIVKNVRNIDSSEGGEKDGHNPTG
NGLHNGFLTASSLDSYSKDGAKSLKGDVPASEVTLKDSTFSQFSPISSAEEFDDDEKIEVDDPPDKEDMRSSFRSNVLTGSAPQQDYDKL
KALGGENSSKTGLSTSGNVEKNKAVKRETEASSINLSVYEPFKVRKAEDKLKESSDKVLENRVLDGKLSSEKNDTSLPSVAPSKTKSSSK
LSSCIAAIAALSAKKAASDSCKEPVANSRESSPLPKEVNDSPRAADKSPESQNLIDGTKKPSLKQPDSPRSISSENSSKGSPSSPAGSTP
AIPKVRIKTIKTSSGEIKRTVTRVLPEVDLDSGKKPSEQTASVMASVTSLLSSPASAAVLSSPPRAPLQSAVVTNAVSPAELTPKQVTIK
PVATAFLPVSAVKTAGSQVINLKLANNTTVKATVISAASVQSASSAIIKAANAIQQQTVVVPASSLANAKLVPKTVHLANLNLLPQGAQA
TSELRQVLTKPQQQIKQAIINAAASQPPKKVSRVQVVSSLQSSVVEAFNKVLSSVNPVPVYIPNLSPPANAGITLPTRGYKCLECGDSFA
LEKSLTQHYDRRSVRIEVTCNHCTKNLVFYNKCSLLSHARGHKEKGVVMQCSHLILKPVPADQMIVSPSSNTSTSTSTLQSPVGAGTHTV
TKIQSGITGTVISAPSSTPITPAMPLDEDPSKLCRHSLKCLECNEVFQDETSLATHFQQAADTSGQKTCTICQMLLPNQCSYASHQRIHQ
HKSPYTCPECGAICRSVHFQTHVTKNCLHYTRRVGFRCVHCNVVYSDVAALKSHIQGSHCEVFYKCPICPMAFKSAPSTHSHAYTQHPGI
KIGEPKIIYKCSMCDTVFTLQTLLYRHFDQHIENQKVSVFKCPDCSLLYAQKQLMMDHIKSMHGTLKSIEGPPNLGINLPLSIKPATQNS
ANQNKEDTKSMNGKEKLEKKSPSPVKKSMETKKVASPGWTCWECDCLFMQRDVYISHVRKEHGKVDLERTFTFRNSKQTYSGIPIIVANM
DTVGTFEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLV
RAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAG
ADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLK

--------------------------------------------------------------
>102294_102294_4_ZNF532-GMPR_ZNF532_chr18_56621031_ENST00000591230_GMPR_chr6_16247073_ENST00000259727_length(transcript)=4818nt_BP=3504nt
ACAGATGCGTTTCCAGAGGCCTCCGTGCCCCCTCTCCCACTGGCCCTGCCTTCGCCCCCCGCCCCCTCCCCAGACAGCCCCAGTTTTCTT
CCCCCGAGGTGAAGGGATTTGGACTTCTCCCCCCAGGTGCTTGAAAGAAGAGAAGGGTATGTTCTGTCTTGTGCTTTTTCTTTTAGAAGC
TACTAAAGGGTGTTGGGGATGCTTCTGACTATTATGAAGGCCAAAAGGCCTGTTGACTGGGGCTGCTTTTAACCCTTTCCTATTTGCTGA
GAATGCAGCCGTGTGACAGTAACTGAACATTGGTCTAAAGTCTTTCCAAAAGGTCAAGGTTCACAAGAACATCTGCTCAAATTAATGACC
ATGGGGGATATGAAGACCCCAGACTTTGATGACCTCCTGGCAGCATTTGACATCCCAGATATGGTCGATCCTAAAGCAGCTATTGAGTCT
GGACACGATGACCATGAAAGCCACATGAAGCAGAATGCTCACGGAGAGGATGACTCCCACGCACCATCATCTTCTGATGTGGGTGTCAGC
GTTATCGTCAAGAATGTTCGGAACATTGACTCTTCCGAGGGCGGGGAGAAAGACGGCCACAACCCCACTGGCAATGGCTTACATAATGGG
TTTCTCACAGCATCCTCCCTTGACAGTTACAGTAAAGATGGAGCAAAGTCCTTGAAAGGAGATGTGCCTGCCTCTGAGGTGACACTGAAA
GACTCGACATTCAGCCAGTTTAGCCCGATCTCCAGTGCTGAAGAGTTTGATGACGACGAGAAGATTGAGGTGGATGACCCCCCTGACAAG
GAGGACATGCGATCAAGCTTCAGGTCGAATGTGTTGACGGGGTCGGCTCCCCAGCAGGACTACGATAAGCTGAAGGCACTCGGAGGGGAA
AACTCCAGCAAAACTGGACTCTCTACGTCAGGCAATGTGGAGAAAAACAAAGCTGTTAAGAGAGAAACAGAAGCCAGTTCTATAAACCTG
AGTGTTTATGAACCTTTTAAAGTCAGAAAAGCAGAGGATAAATTGAAGGAAAGCTCTGACAAGGTGCTGGAAAACAGAGTCCTAGATGGG
AAGCTGAGCTCCGAGAAGAATGACACCAGCCTCCCCAGCGTTGCGCCATCAAAGACAAAGTCGTCCTCCAAGCTCTCGTCCTGCATCGCT
GCCATCGCGGCTCTCAGCGCTAAAAAGGCGGCTTCAGACTCCTGCAAAGAACCAGTGGCCAATTCGAGGGAATCCTCCCCGTTACCAAAA
GAAGTAAATGACAGTCCGAGAGCCGCTGACAAGTCTCCTGAATCCCAGAATCTCATCGACGGGACCAAAAAACCATCCCTGAAGCAACCG
GATAGTCCCAGAAGCATCTCAAGTGAGAACAGCAGCAAAGGATCCCCGTCCTCTCCCGCAGGGTCCACACCAGCAATCCCCAAAGTCCGC
ATAAAAACCATTAAGACATCTTCTGGGGAAATCAAGAGAACAGTGACCAGGGTATTGCCAGAAGTGGATCTTGACTCTGGAAAGAAACCT
TCCGAGCAGACAGCGTCCGTGATGGCCTCTGTGACATCCCTTCTGTCGTCTCCAGCATCAGCCGCCGTCCTTTCCTCTCCCCCCAGGGCG
CCTCTCCAGTCTGCGGTCGTGACCAATGCAGTTTCCCCTGCAGAGCTCACCCCCAAACAGGTCACAATCAAGCCTGTGGCTACTGCTTTC
CTCCCAGTGTCTGCTGTGAAGACGGCAGGATCCCAAGTCATTAATTTGAAGCTCGCTAACAACACCACGGTGAAAGCCACGGTCATATCT
GCTGCCTCTGTCCAGAGTGCCAGCAGCGCCATCATTAAAGCTGCCAACGCCATCCAGCAGCAAACTGTCGTGGTGCCGGCATCCAGCCTG
GCCAATGCCAAACTCGTGCCAAAGACTGTGCACCTTGCCAACCTTAACCTTTTGCCTCAGGGTGCCCAGGCCACCTCTGAACTCCGCCAA
GTGCTAACCAAACCTCAGCAACAAATAAAGCAGGCAATAATCAATGCAGCAGCCTCGCAACCCCCCAAAAAGGTGTCTCGAGTCCAGGTG
GTGTCGTCCTTGCAGAGTTCTGTGGTGGAAGCTTTCAACAAGGTGCTGAGCAGTGTCAATCCAGTCCCTGTTTACATCCCAAACCTCAGT
CCTCCCGCCAATGCAGGGATCACGTTACCGACGCGTGGGTACAAGTGCTTGGAGTGTGGGGACTCCTTTGCACTTGAAAAGAGTCTGACC
CAGCACTACGACAGACGGAGCGTGCGCATCGAAGTAACGTGCAACCATTGTACAAAGAACCTCGTTTTTTACAACAAATGCAGCCTCCTT
TCCCATGCCCGTGGGCATAAGGAGAAAGGGGTGGTAATGCAATGCTCCCACTTAATTTTAAAGCCAGTCCCAGCAGATCAAATGATAGTT
TCTCCGTCAAGCAATACTTCCACTTCAACTTCCACTCTTCAGAGCCCTGTGGGAGCTGGCACACACACTGTCACAAAAATTCAGTCTGGC
ATAACTGGGACAGTCATATCGGCTCCTTCAAGCACTCCCATCACCCCAGCCATGCCCCTAGATGAAGACCCCTCCAAACTGTGTAGACAT
AGTCTAAAATGTTTGGAGTGTAATGAAGTCTTCCAGGACGAGACATCACTGGCTACACATTTCCAGCAGGCTGCAGATACGAGTGGACAA
AAGACTTGCACTATCTGCCAGATGCTGCTTCCTAACCAGTGCAGTTATGCATCACACCAGAGAATCCATCAGCACAAATCTCCCTACACC
TGCCCTGAGTGTGGGGCCATCTGCAGGTCGGTGCACTTCCAGACCCACGTCACCAAGAACTGTCTGCACTACACGAGGAGAGTTGGTTTT
CGATGTGTGCATTGCAATGTTGTGTACTCTGATGTGGCTGCTCTGAAGTCTCACATTCAAGGTTCTCACTGTGAAGTCTTCTACAAGTGT
CCTATTTGTCCAATGGCGTTTAAGTCTGCCCCAAGCACACATTCCCACGCCTACACACAGCATCCTGGCATCAAGATAGGAGAACCAAAA
ATAATATATAAGTGTTCCATGTGCGACACTGTGTTCACCCTGCAAACCTTGCTGTATCGCCACTTTGACCAACACATTGAAAACCAGAAG
GTGTCTGTTTTCAAGTGTCCAGACTGTTCTCTTTTATATGCACAGAAGCAACTTATGATGGACCATATCAAGTCTATGCATGGAACATTG
AAAAGTATTGAAGGGCCTCCAAACTTGGGTATAAACTTGCCTTTGAGCATTAAGCCTGCAACTCAAAATTCAGCAAATCAGAACAAAGAG
GACACCAAATCCATGAATGGGAAAGAGAAATTGGAAAAGAAATCTCCATCTCCTGTGAAAAAATCAATGGAAACCAAGAAAGTGGCCAGT
CCTGGGTGGACGTGTTGGGAGTGTGACTGCCTGTTCATGCAGAGAGATGTGTACATATCCCACGTGAGGAAGGAGCACGGGAAGGTGGAT
CTTGAACGCACCTTCACGTTTCGAAATTCAAAGCAGACCTACTCAGGGATTCCCATCATCGTGGCCAACATGGACACTGTGGGCACGTTT
GAGATGGCAGCCGTGATGTCACAGCACTCCATGTTTACAGCAATTCATAAGCATTACTCCCTGGATGACTGGAAGCTCTTTGCCACAAAT
CACCCAGAATGCCTGCAGAATGTAGCCGTGAGTTCAGGCAGTGGGCAGAATGATCTGGAAAAGATGACCAGCATCCTGGAAGCTGTGCCA
CAGGTTAAGTTTATTTGCCTGGATGTGGCCAATGGGTATTCAGAACATTTTGTGGAATTCGTGAAACTTGTCCGTGCCAAATTTCCTGAA
CACACCATTATGGCAGGGAACGTGGTGACAGGAGAAATGGTAGAAGAGCTTATTCTTTCCGGAGCAGATATCATCAAAGTGGGAGTTGGA
CCAGGTTCTGTGTGCACCACCCGCACCAAGACGGGAGTGGGGTACCCCCAGCTGAGTGCCGTCATTGAGTGTGCCGACTCTGCCCATGGC
CTGAAGGGCCACATCATCTCTGATGGAGGCTGTACGTGTCCAGGGGATGTCGCCAAAGCCTTTGGAGCTGGAGCAGATTTTGTCATGCTG
GGAGGAATGTTTTCGGGTCATACGGAGTGTGCTGGAGAAGTGTTTGAGAGGAACGGACGGAAGCTCAAGCTCTTCTACGGGATGAGCTCT
GACACCGCCATGAACAAGCACGCAGGAGGAGTTGCTGAGTACAGAGCCTCTGAGGGTAAGACTGTGGAAGTTCCTTACAAAGGAGATGTG
GAAAACACTATCCTGGATATTCTCGGGGGACTGAGGTCCACGTGCACCTACGTGGGGGCCGCCAAACTCAAGGAGCTCAGCAGGAGGGCA
ACATTCATCCGGGTGACCCAGCAGCACAACACCGTGTTCAGCTAACCCTGGGGACAAAGCAGCGTCTGGCTCGAGTGGAAGCGTCCAAAC
CTGCTTTTCCCATCTCCCCCCAAGTCTGTTCCGTCAGAGCTTCTGGCTGCTCCTGAATGGTGGAATGCTGTGTCCTCTCTTCTGTCTCCT
GCTGCCTGGAGGCTTCGGGGCTCTCCCGCCTGCCTTCTCGGGGCCCAGACGCAAGGCACCGATTGGGCCAACATCAGAGCCCTGCTGCCC
AGAACTCATAACCTCATTGTTCAAACCAACACTTGCACCTTTCTCTTTTTCTCTTTCTCTCTCCCTTTCTTTGTTTTTCTTTCTTTTTTA

>102294_102294_4_ZNF532-GMPR_ZNF532_chr18_56621031_ENST00000591230_GMPR_chr6_16247073_ENST00000259727_length(amino acids)=1370AA_BP=1054
MLKLMTMGDMKTPDFDDLLAAFDIPDMVDPKAAIESGHDDHESHMKQNAHGEDDSHAPSSSDVGVSVIVKNVRNIDSSEGGEKDGHNPTG
NGLHNGFLTASSLDSYSKDGAKSLKGDVPASEVTLKDSTFSQFSPISSAEEFDDDEKIEVDDPPDKEDMRSSFRSNVLTGSAPQQDYDKL
KALGGENSSKTGLSTSGNVEKNKAVKRETEASSINLSVYEPFKVRKAEDKLKESSDKVLENRVLDGKLSSEKNDTSLPSVAPSKTKSSSK
LSSCIAAIAALSAKKAASDSCKEPVANSRESSPLPKEVNDSPRAADKSPESQNLIDGTKKPSLKQPDSPRSISSENSSKGSPSSPAGSTP
AIPKVRIKTIKTSSGEIKRTVTRVLPEVDLDSGKKPSEQTASVMASVTSLLSSPASAAVLSSPPRAPLQSAVVTNAVSPAELTPKQVTIK
PVATAFLPVSAVKTAGSQVINLKLANNTTVKATVISAASVQSASSAIIKAANAIQQQTVVVPASSLANAKLVPKTVHLANLNLLPQGAQA
TSELRQVLTKPQQQIKQAIINAAASQPPKKVSRVQVVSSLQSSVVEAFNKVLSSVNPVPVYIPNLSPPANAGITLPTRGYKCLECGDSFA
LEKSLTQHYDRRSVRIEVTCNHCTKNLVFYNKCSLLSHARGHKEKGVVMQCSHLILKPVPADQMIVSPSSNTSTSTSTLQSPVGAGTHTV
TKIQSGITGTVISAPSSTPITPAMPLDEDPSKLCRHSLKCLECNEVFQDETSLATHFQQAADTSGQKTCTICQMLLPNQCSYASHQRIHQ
HKSPYTCPECGAICRSVHFQTHVTKNCLHYTRRVGFRCVHCNVVYSDVAALKSHIQGSHCEVFYKCPICPMAFKSAPSTHSHAYTQHPGI
KIGEPKIIYKCSMCDTVFTLQTLLYRHFDQHIENQKVSVFKCPDCSLLYAQKQLMMDHIKSMHGTLKSIEGPPNLGINLPLSIKPATQNS
ANQNKEDTKSMNGKEKLEKKSPSPVKKSMETKKVASPGWTCWECDCLFMQRDVYISHVRKEHGKVDLERTFTFRNSKQTYSGIPIIVANM
DTVGTFEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLV
RAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAG
ADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLK

--------------------------------------------------------------
>102294_102294_5_ZNF532-GMPR_ZNF532_chr18_56621031_ENST00000591808_GMPR_chr6_16247073_ENST00000259727_length(transcript)=5353nt_BP=4039nt
CTTGCGAGGTGAGCATTTCCAAGGCTGTGTGCTCGTGGGGTGGGGGGACACACGATGACCTTCTCCTCCTCAGGAAGACCTAAGAGGGAA
GAGCAAACCCCAGCGAGATCCCCCCTGTGCTGATGATTTTCAGGGACTTGTTGGCAACTCAGCGAGGGTTGCCATAGCTTTTTTATGTAG
GGTGACCAGAACCGGCTGAAACTGGTTTGAGGCAGATCAGCTCCTGAACACAATGCAGTCACTGAGCTACTACAGTAGGATAGCAGCTTC
CTCCCTTCATGGCAGCCAAAAGCAGAGGAGCTTGCAGGAAGGTACCATCCCTACACAGTATGTGAATGCACACTTAGACACCACACAGCA
CTGGTACGTGACTAATGGAGCCCTAAAAGATTCTGGGTAGAGAAGATGGAAAAAAAGGTGCAGGTTTGCAGGGTCTGAGATTACTTGGGC
TTTTCCTGCCTTTTTCTTTTGCTTAAGGGATGGACAAGGAGCTGAGATTTATGACCCTTATTAGAGAAAAAAATGTGCCTTGCTAGGGTG
GGGACACTTGGTTGATGCAGTCTCTCTCTCTCTTTCTCGGTGTTTATAACAAAACAAAACCAAAATGAACTGAGGGGTTTGTAATGGTAG
TTTGTTTGTTGCTGGAGAATGCTACTTTGCATGCTTTTTTTCTCTTGCAGGGTATGTTCTGTCTTGTGCTTTTTCTTTTAGAAGCTACTA
AAGGGTGTTGGGGATGCTTCTGACTATTATGAAGGCCAAAAGGCCTGTTGACTGGGGCTGCTTTTAACCCTTTCCTATTTGCTGAGAATG
CAGCCGTGTGACAGTAACTGAACATTGGTCTAAAGTCTTTCCAAAAGGTCAAGGTTCACAAGAACATCTGCTCAAATTAATGACCATGGG
GGATATGAAGACCCCAGACTTTGATGACCTCCTGGCAGCATTTGACATCCCAGATATGGTCGATCCTAAAGCAGCTATTGAGTCTGGACA
CGATGACCATGAAAGCCACATGAAGCAGAATGCTCACGGAGAGGATGACTCCCACGCACCATCATCTTCTGATGTGGGTGTCAGCGTTAT
CGTCAAGAATGTTCGGAACATTGACTCTTCCGAGGGCGGGGAGAAAGACGGCCACAACCCCACTGGCAATGGCTTACATAATGGGTTTCT
CACAGCATCCTCCCTTGACAGTTACAGTAAAGATGGAGCAAAGTCCTTGAAAGGAGATGTGCCTGCCTCTGAGGTGACACTGAAAGACTC
GACATTCAGCCAGTTTAGCCCGATCTCCAGTGCTGAAGAGTTTGATGACGACGAGAAGATTGAGGTGGATGACCCCCCTGACAAGGAGGA
CATGCGATCAAGCTTCAGGTCGAATGTGTTGACGGGGTCGGCTCCCCAGCAGGACTACGATAAGCTGAAGGCACTCGGAGGGGAAAACTC
CAGCAAAACTGGACTCTCTACGTCAGGCAATGTGGAGAAAAACAAAGCTGTTAAGAGAGAAACAGAAGCCAGTTCTATAAACCTGAGTGT
TTATGAACCTTTTAAAGTCAGAAAAGCAGAGGATAAATTGAAGGAAAGCTCTGACAAGGTGCTGGAAAACAGAGTCCTAGATGGGAAGCT
GAGCTCCGAGAAGAATGACACCAGCCTCCCCAGCGTTGCGCCATCAAAGACAAAGTCGTCCTCCAAGCTCTCGTCCTGCATCGCTGCCAT
CGCGGCTCTCAGCGCTAAAAAGGCGGCTTCAGACTCCTGCAAAGAACCAGTGGCCAATTCGAGGGAATCCTCCCCGTTACCAAAAGAAGT
AAATGACAGTCCGAGAGCCGCTGACAAGTCTCCTGAATCCCAGAATCTCATCGACGGGACCAAAAAACCATCCCTGAAGCAACCGGATAG
TCCCAGAAGCATCTCAAGTGAGAACAGCAGCAAAGGATCCCCGTCCTCTCCCGCAGGGTCCACACCAGCAATCCCCAAAGTCCGCATAAA
AACCATTAAGACATCTTCTGGGGAAATCAAGAGAACAGTGACCAGGGTATTGCCAGAAGTGGATCTTGACTCTGGAAAGAAACCTTCCGA
GCAGACAGCGTCCGTGATGGCCTCTGTGACATCCCTTCTGTCGTCTCCAGCATCAGCCGCCGTCCTTTCCTCTCCCCCCAGGGCGCCTCT
CCAGTCTGCGGTCGTGACCAATGCAGTTTCCCCTGCAGAGCTCACCCCCAAACAGGTCACAATCAAGCCTGTGGCTACTGCTTTCCTCCC
AGTGTCTGCTGTGAAGACGGCAGGATCCCAAGTCATTAATTTGAAGCTCGCTAACAACACCACGGTGAAAGCCACGGTCATATCTGCTGC
CTCTGTCCAGAGTGCCAGCAGCGCCATCATTAAAGCTGCCAACGCCATCCAGCAGCAAACTGTCGTGGTGCCGGCATCCAGCCTGGCCAA
TGCCAAACTCGTGCCAAAGACTGTGCACCTTGCCAACCTTAACCTTTTGCCTCAGGGTGCCCAGGCCACCTCTGAACTCCGCCAAGTGCT
AACCAAACCTCAGCAACAAATAAAGCAGGCAATAATCAATGCAGCAGCCTCGCAACCCCCCAAAAAGGTGTCTCGAGTCCAGGTGGTGTC
GTCCTTGCAGAGTTCTGTGGTGGAAGCTTTCAACAAGGTGCTGAGCAGTGTCAATCCAGTCCCTGTTTACATCCCAAACCTCAGTCCTCC
CGCCAATGCAGGGATCACGTTACCGACGCGTGGGTACAAGTGCTTGGAGTGTGGGGACTCCTTTGCACTTGAAAAGAGTCTGACCCAGCA
CTACGACAGACGGAGCGTGCGCATCGAAGTAACGTGCAACCATTGTACAAAGAACCTCGTTTTTTACAACAAATGCAGCCTCCTTTCCCA
TGCCCGTGGGCATAAGGAGAAAGGGGTGGTAATGCAATGCTCCCACTTAATTTTAAAGCCAGTCCCAGCAGATCAAATGATAGTTTCTCC
GTCAAGCAATACTTCCACTTCAACTTCCACTCTTCAGAGCCCTGTGGGAGCTGGCACACACACTGTCACAAAAATTCAGTCTGGCATAAC
TGGGACAGTCATATCGGCTCCTTCAAGCACTCCCATCACCCCAGCCATGCCCCTAGATGAAGACCCCTCCAAACTGTGTAGACATAGTCT
AAAATGTTTGGAGTGTAATGAAGTCTTCCAGGACGAGACATCACTGGCTACACATTTCCAGCAGGCTGCAGATACGAGTGGACAAAAGAC
TTGCACTATCTGCCAGATGCTGCTTCCTAACCAGTGCAGTTATGCATCACACCAGAGAATCCATCAGCACAAATCTCCCTACACCTGCCC
TGAGTGTGGGGCCATCTGCAGGTCGGTGCACTTCCAGACCCACGTCACCAAGAACTGTCTGCACTACACGAGGAGAGTTGGTTTTCGATG
TGTGCATTGCAATGTTGTGTACTCTGATGTGGCTGCTCTGAAGTCTCACATTCAAGGTTCTCACTGTGAAGTCTTCTACAAGTGTCCTAT
TTGTCCAATGGCGTTTAAGTCTGCCCCAAGCACACATTCCCACGCCTACACACAGCATCCTGGCATCAAGATAGGAGAACCAAAAATAAT
ATATAAGTGTTCCATGTGCGACACTGTGTTCACCCTGCAAACCTTGCTGTATCGCCACTTTGACCAACACATTGAAAACCAGAAGGTGTC
TGTTTTCAAGTGTCCAGACTGTTCTCTTTTATATGCACAGAAGCAACTTATGATGGACCATATCAAGTCTATGCATGGAACATTGAAAAG
TATTGAAGGGCCTCCAAACTTGGGTATAAACTTGCCTTTGAGCATTAAGCCTGCAACTCAAAATTCAGCAAATCAGAACAAAGAGGACAC
CAAATCCATGAATGGGAAAGAGAAATTGGAAAAGAAATCTCCATCTCCTGTGAAAAAATCAATGGAAACCAAGAAAGTGGCCAGTCCTGG
GTGGACGTGTTGGGAGTGTGACTGCCTGTTCATGCAGAGAGATGTGTACATATCCCACGTGAGGAAGGAGCACGGGAAGGTGGATCTTGA
ACGCACCTTCACGTTTCGAAATTCAAAGCAGACCTACTCAGGGATTCCCATCATCGTGGCCAACATGGACACTGTGGGCACGTTTGAGAT
GGCAGCCGTGATGTCACAGCACTCCATGTTTACAGCAATTCATAAGCATTACTCCCTGGATGACTGGAAGCTCTTTGCCACAAATCACCC
AGAATGCCTGCAGAATGTAGCCGTGAGTTCAGGCAGTGGGCAGAATGATCTGGAAAAGATGACCAGCATCCTGGAAGCTGTGCCACAGGT
TAAGTTTATTTGCCTGGATGTGGCCAATGGGTATTCAGAACATTTTGTGGAATTCGTGAAACTTGTCCGTGCCAAATTTCCTGAACACAC
CATTATGGCAGGGAACGTGGTGACAGGAGAAATGGTAGAAGAGCTTATTCTTTCCGGAGCAGATATCATCAAAGTGGGAGTTGGACCAGG
TTCTGTGTGCACCACCCGCACCAAGACGGGAGTGGGGTACCCCCAGCTGAGTGCCGTCATTGAGTGTGCCGACTCTGCCCATGGCCTGAA
GGGCCACATCATCTCTGATGGAGGCTGTACGTGTCCAGGGGATGTCGCCAAAGCCTTTGGAGCTGGAGCAGATTTTGTCATGCTGGGAGG
AATGTTTTCGGGTCATACGGAGTGTGCTGGAGAAGTGTTTGAGAGGAACGGACGGAAGCTCAAGCTCTTCTACGGGATGAGCTCTGACAC
CGCCATGAACAAGCACGCAGGAGGAGTTGCTGAGTACAGAGCCTCTGAGGGTAAGACTGTGGAAGTTCCTTACAAAGGAGATGTGGAAAA
CACTATCCTGGATATTCTCGGGGGACTGAGGTCCACGTGCACCTACGTGGGGGCCGCCAAACTCAAGGAGCTCAGCAGGAGGGCAACATT
CATCCGGGTGACCCAGCAGCACAACACCGTGTTCAGCTAACCCTGGGGACAAAGCAGCGTCTGGCTCGAGTGGAAGCGTCCAAACCTGCT
TTTCCCATCTCCCCCCAAGTCTGTTCCGTCAGAGCTTCTGGCTGCTCCTGAATGGTGGAATGCTGTGTCCTCTCTTCTGTCTCCTGCTGC
CTGGAGGCTTCGGGGCTCTCCCGCCTGCCTTCTCGGGGCCCAGACGCAAGGCACCGATTGGGCCAACATCAGAGCCCTGCTGCCCAGAAC
TCATAACCTCATTGTTCAAACCAACACTTGCACCTTTCTCTTTTTCTCTTTCTCTCTCCCTTTCTTTGTTTTTCTTTCTTTTTTAAAAGA

>102294_102294_5_ZNF532-GMPR_ZNF532_chr18_56621031_ENST00000591808_GMPR_chr6_16247073_ENST00000259727_length(amino acids)=1370AA_BP=1054
MLKLMTMGDMKTPDFDDLLAAFDIPDMVDPKAAIESGHDDHESHMKQNAHGEDDSHAPSSSDVGVSVIVKNVRNIDSSEGGEKDGHNPTG
NGLHNGFLTASSLDSYSKDGAKSLKGDVPASEVTLKDSTFSQFSPISSAEEFDDDEKIEVDDPPDKEDMRSSFRSNVLTGSAPQQDYDKL
KALGGENSSKTGLSTSGNVEKNKAVKRETEASSINLSVYEPFKVRKAEDKLKESSDKVLENRVLDGKLSSEKNDTSLPSVAPSKTKSSSK
LSSCIAAIAALSAKKAASDSCKEPVANSRESSPLPKEVNDSPRAADKSPESQNLIDGTKKPSLKQPDSPRSISSENSSKGSPSSPAGSTP
AIPKVRIKTIKTSSGEIKRTVTRVLPEVDLDSGKKPSEQTASVMASVTSLLSSPASAAVLSSPPRAPLQSAVVTNAVSPAELTPKQVTIK
PVATAFLPVSAVKTAGSQVINLKLANNTTVKATVISAASVQSASSAIIKAANAIQQQTVVVPASSLANAKLVPKTVHLANLNLLPQGAQA
TSELRQVLTKPQQQIKQAIINAAASQPPKKVSRVQVVSSLQSSVVEAFNKVLSSVNPVPVYIPNLSPPANAGITLPTRGYKCLECGDSFA
LEKSLTQHYDRRSVRIEVTCNHCTKNLVFYNKCSLLSHARGHKEKGVVMQCSHLILKPVPADQMIVSPSSNTSTSTSTLQSPVGAGTHTV
TKIQSGITGTVISAPSSTPITPAMPLDEDPSKLCRHSLKCLECNEVFQDETSLATHFQQAADTSGQKTCTICQMLLPNQCSYASHQRIHQ
HKSPYTCPECGAICRSVHFQTHVTKNCLHYTRRVGFRCVHCNVVYSDVAALKSHIQGSHCEVFYKCPICPMAFKSAPSTHSHAYTQHPGI
KIGEPKIIYKCSMCDTVFTLQTLLYRHFDQHIENQKVSVFKCPDCSLLYAQKQLMMDHIKSMHGTLKSIEGPPNLGINLPLSIKPATQNS
ANQNKEDTKSMNGKEKLEKKSPSPVKKSMETKKVASPGWTCWECDCLFMQRDVYISHVRKEHGKVDLERTFTFRNSKQTYSGIPIIVANM
DTVGTFEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLV
RAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAG
ADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNF532-GMPR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF532-GMPR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF532-GMPR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource