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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF544-AP2A1 (FusionGDB2 ID:102327)

Fusion Gene Summary for ZNF544-AP2A1

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF544-AP2A1
Fusion gene ID: 102327
HgeneTgene
Gene symbol

ZNF544

AP2A1

Gene ID

27300

160

Gene namezinc finger protein 544adaptor related protein complex 2 subunit alpha 1
Synonyms-ADTAA|AP2-ALPHA|CLAPA1
Cytomap

19q13.43

19q13.33

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 544AP-2 complex subunit alpha-1100 kDa coated vesicle protein Aadapter-related protein complex 2 alpha-1 subunitadapter-related protein complex 2 subunit alpha-1adaptin, alpha Aadaptor protein complex AP-2 subunit alpha-1adaptor related protein complex
Modification date2020031320200313
UniProtAcc.

O95782

Ensembl transtripts involved in fusion geneENST00000596597, ENST00000269829, 
ENST00000333581, ENST00000594384, 
ENST00000595981, ENST00000596652, 
ENST00000596825, ENST00000596929, 
ENST00000599227, ENST00000599953, 
ENST00000415203, ENST00000600044, 
ENST00000600220, 		ENST00000354293, 
ENST00000359032, ENST00000600199, 
Fusion gene scores* DoF score8 X 4 X 6=19213 X 12 X 6=936
# samples 1115
** MAII scorelog2(11/192*10)=-0.803602787196497
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/936*10)=-2.64154602908752
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF544 [Title/Abstract] AND AP2A1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF544(58758160)-AP2A1(50285014), # samples:3
Anticipated loss of major functional domain due to fusion event.ZNF544-AP2A1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
ZNF544-AP2A1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneAP2A1

GO:0072583

clathrin-dependent endocytosis

23676497

TgeneAP2A1

GO:1900126

negative regulation of hyaluronan biosynthetic process

24251095


check buttonFusion gene breakpoints across ZNF544 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AP2A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-32-1970-01AZNF544chr19

58758160

-AP2A1chr19

50285014

+
ChimerDB4GBMTCGA-32-1970-01AZNF544chr19

58758160

+AP2A1chr19

50285014

+


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Fusion Gene ORF analysis for ZNF544-AP2A1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000596597ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
3UTR-3UTRENST00000596597ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
3UTR-3UTRENST00000596597ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000269829ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000269829ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000333581ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000333581ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000594384ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000594384ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000595981ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000595981ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000596652ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000596652ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000596825ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000596825ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000596929ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000596929ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000599227ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5CDS-3UTRENST00000599227ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5UTR-3CDSENST00000599953ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5UTR-3UTRENST00000599953ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
5UTR-3UTRENST00000599953ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
Frame-shiftENST00000594384ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
Frame-shiftENST00000596825ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
Frame-shiftENST00000599227ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
In-frameENST00000269829ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
In-frameENST00000333581ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
In-frameENST00000595981ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
In-frameENST00000596652ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
In-frameENST00000596929ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
intron-3CDSENST00000415203ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
intron-3CDSENST00000600044ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
intron-3CDSENST00000600220ENST00000354293ZNF544chr19

58758160

+AP2A1chr19

50285014

+
intron-3UTRENST00000415203ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
intron-3UTRENST00000415203ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
intron-3UTRENST00000600044ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
intron-3UTRENST00000600044ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+
intron-3UTRENST00000600220ENST00000359032ZNF544chr19

58758160

+AP2A1chr19

50285014

+
intron-3UTRENST00000600220ENST00000600199ZNF544chr19

58758160

+AP2A1chr19

50285014

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000269829ZNF544chr1958758160+ENST00000354293AP2A1chr1950285014+387371837235181048
ENST00000333581ZNF544chr1958758160+ENST00000354293AP2A1chr1950285014+363347813232781048
ENST00000596652ZNF544chr1958758160+ENST00000354293AP2A1chr1950285014+363347813232781048
ENST00000596929ZNF544chr1958758160+ENST00000354293AP2A1chr1950285014+363347813232781048
ENST00000595981ZNF544chr1958758160+ENST00000354293AP2A1chr1950285014+363047512932751048

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000269829ENST00000354293ZNF544chr1958758160+AP2A1chr1950285014+0.0044537010.99554634
ENST00000333581ENST00000354293ZNF544chr1958758160+AP2A1chr1950285014+0.0031827760.99681723
ENST00000596652ENST00000354293ZNF544chr1958758160+AP2A1chr1950285014+0.0031827760.99681723
ENST00000596929ENST00000354293ZNF544chr1958758160+AP2A1chr1950285014+0.0031827760.99681723
ENST00000595981ENST00000354293ZNF544chr1958758160+AP2A1chr1950285014+0.0031749150.9968251

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Fusion Genomic Features for ZNF544-AP2A1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNF544chr1958758160+AP2A1chr1950285013+3.30E-050.9999671
ZNF544chr1958758160+AP2A1chr1950285013+3.30E-050.9999671

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZNF544-AP2A1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:58758160/chr19:50285014)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AP2A1

O95782

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. During long-term potentiation in hippocampal neurons, AP-2 is responsible for the endocytosis of ADAM10 (PubMed:23676497). The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif (By similarity). {ECO:0000250, ECO:0000269|PubMed:14745134, ECO:0000269|PubMed:15473838, ECO:0000269|PubMed:19033387, ECO:0000269|PubMed:23676497}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+6714_8581716.0DomainKRAB
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+5614_8581716.0DomainKRAB
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67354_37481716.0Zinc fingerC2H2-type 1%3B atypical
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67380_40281716.0Zinc fingerC2H2-type 2
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67408_43081716.0Zinc fingerC2H2-type 3
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67436_45881716.0Zinc fingerC2H2-type 4
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67464_48681716.0Zinc fingerC2H2-type 5
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67492_51481716.0Zinc fingerC2H2-type 6
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67520_54281716.0Zinc fingerC2H2-type 7
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67548_57081716.0Zinc fingerC2H2-type 8
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67576_59881716.0Zinc fingerC2H2-type 9
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67604_62681716.0Zinc fingerC2H2-type 10
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67632_65481716.0Zinc fingerC2H2-type 11
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67660_68281716.0Zinc fingerC2H2-type 12
HgeneZNF544chr19:58758160chr19:50285014ENST00000269829+67688_71081716.0Zinc fingerC2H2-type 13
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56354_37481716.0Zinc fingerC2H2-type 1%3B atypical
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56380_40281716.0Zinc fingerC2H2-type 2
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56408_43081716.0Zinc fingerC2H2-type 3
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56436_45881716.0Zinc fingerC2H2-type 4
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56464_48681716.0Zinc fingerC2H2-type 5
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56492_51481716.0Zinc fingerC2H2-type 6
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56520_54281716.0Zinc fingerC2H2-type 7
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56548_57081716.0Zinc fingerC2H2-type 8
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56576_59881716.0Zinc fingerC2H2-type 9
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56604_62681716.0Zinc fingerC2H2-type 10
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56632_65481716.0Zinc fingerC2H2-type 11
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56660_68281716.0Zinc fingerC2H2-type 12
HgeneZNF544chr19:58758160chr19:50285014ENST00000596652+56688_71081716.0Zinc fingerC2H2-type 13


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Fusion Gene Sequence for ZNF544-AP2A1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102327_102327_1_ZNF544-AP2A1_ZNF544_chr19_58758160_ENST00000269829_AP2A1_chr19_50285014_ENST00000354293_length(transcript)=3873nt_BP=718nt
GGGGAGGGGACAGGCGCTGCAAGGAGCAGAGCCGCGGGAAGCAACTCCCTAAGCCACAATGCTAGTCGCGAACACAGGAAAAAGCTCATC
CCGCCGCCGCGGGGCCCCATGCTCCCGCCGGCAATGACTATGCCTGTGGGAGCAACGGCTACCGGCGCGCGGCCTTCTGGGAGTTGTTTG
TTGCGCGGAGCGCGGGCACGTCCGCCGGCCACCGGAAGCACCGCCATTGGCCGGTGCGTGCAGGTGGCAGCCAAGAGCCTCCTGGCACAG
CGGCACCAGGCAGGTGACGCCTATTGGACCCCAGAGGTCATCCCAGCTCCAGACGTGGACACATTTTCTTCCAATGATGTCTACGGATGA
GGAAACTGAGGCCTGGAGAGGTTAAAGAGACCCGTTCAGAGTCCTACAGTGGCAGACTGGTCTTCTGAGGACCTCTGCCCTCTACACAGC
GGCCTCTTCAGGTGCAGGGAGGAAATGGAAGCACGTTCTATGCTGGTTCCACCCCAGGCATCTGTGTGCTTCGAGGATGTGGCTATGGCA
TTCACACAGGAGGAGTGGGAACAGCTGGACCTGGCCCAGAGGACACTGTACCGAGAGGTGACACTGGAGACCTGGGAGCATATTGTCTCC
CTGGGGCTTTTCCTTTCCAAATCTGATGTGATCTCTCAGCTGGAGCAAGAAGAGGACCTGTGCAGGGCAGAGCAGGAGGCCCCCCGAGGT
AAGAGCAAAGAGGCGGAAATTAAGAGAATCAACAAGGAACTGGCCAACATCCGCTCCAAGTTCAAAGGAGACAAAGCCTTGGATGGCTAC
AGTAAGAAAAAATATGTGTGTAAACTGCTTTTCATCTTCCTGCTTGGCCATGACATTGACTTTGGGCACATGGAGGCTGTGAATCTGTTG
AGTTCCAATAAATACACAGAGAAGCAAATAGGTTACCTGTTCATTTCTGTGCTGGTGAACTCGAACTCGGAGCTGATCCGCCTCATCAAC
AACGCCATCAAGAATGACCTGGCCAGCCGCAACCCCACCTTCATGTGCCTGGCCCTGCACTGCATCGCCAACGTGGGCAGCCGGGAGATG
GGCGAGGCCTTTGCCGCTGACATCCCCCGCATCCTGGTGGCCGGGGACAGCATGGACAGTGTCAAGCAGAGTGCGGCCCTGTGCCTCCTT
CGACTGTACAAGGCCTCGCCTGACCTGGTGCCCATGGGCGAGTGGACGGCGCGTGTGGTACACCTGCTCAATGACCAGCACATGGGTGTG
GTCACGGCCGCCGTCAGCCTCATCACCTGTCTCTGCAAGAAGAACCCAGATGACTTCAAGACGTGCGTCTCTCTGGCTGTGTCGCGCCTG
AGCCGGATCGTCTCCTCTGCCTCCACCGACCTCCAGGACTACACCTACTACTTCGTCCCAGCACCCTGGCTCTCGGTGAAGCTCCTGCGG
CTGCTGCAGTGCTACCCGCCTCCAGAGGATGCGGCTGTGAAGGGGCGGCTGGTGGAATGTCTGGAGACTGTGCTCAACAAGGCCCAGGAG
CCCCCCAAATCCAAGAAGGTGCAGCATTCCAACGCCAAGAACGCCATCCTCTTCGAGACCATCAGCCTCATCATCCACTATGACAGTGAG
CCCAACCTCCTGGTTCGGGCCTGCAACCAGCTGGGCCAGTTCCTGCAGCACCGGGAGACCAACCTGCGCTACCTGGCCCTGGAGAGCATG
TGCACGCTGGCCAGCTCCGAGTTCTCCCATGAAGCCGTCAAGACGCACATTGACACCGTCATCAATGCCCTCAAGACGGAGCGGGACGTC
AGCGTGCGGCAGCGGGCGGCTGACCTCCTCTACGCCATGTGTGACCGGAGCAATGCCAAGCAGATCGTGTCGGAGATGCTGCGGTACCTG
GAGACGGCAGACTACGCCATCCGCGAGGAGATCGTCCTGAAGGTGGCCATCCTGGCCGAGAAGTACGCCGTGGACTACAGCTGGTACGTG
GACACCATCCTCAACCTCATCCGCATTGCGGGCGACTACGTGAGTGAGGAGGTGTGGTACCGTGTGCTACAGATCGTCACCAACCGTGAT
GACGTCCAGGGCTATGCCGCCAAGACCGTCTTTGAGGCGCTCCAGGCCCCTGCCTGTCACGAGAACATGGTGAAGGTTGGCGGCTACATC
CTTGGGGAGTTTGGGAACCTGATTGCTGGGGACCCCCGCTCCAGCCCCCCAGTGCAGTTCTCCCTGCTCCACTCCAAGTTCCATCTGTGC
AGCGTGGCCACGCGGGCGCTGCTGCTGTCCACCTACATCAAGTTCATCAACCTCTTCCCCGAGACCAAGGCCACCATCCAGGGCGTCCTG
CGGGCCGGCTCCCAGCTGCGCAATGCTGACGTGGAGCTGCAGCAGCGAGCCGTGGAGTACCTCACCCTCAGCTCAGTGGCCAGCACCGAC
GTCCTGGCCACGGTGCTGGAGGAGATGCCGCCCTTCCCCGAGCGCGAGTCGTCCATCCTGGCCAAGCTGAAACGCAAGAAGGGGCCAGGG
GCCGGCAGCGCCCTGGACGATGGCCGGAGGGACCCCAGCAGCAACGACATCAACGGGGGCATGGAGCCCACCCCCAGCACTGTGTCGACG
CCCTCGCCCTCCGCCGACCTCCTGGGGCTGCGGGCAGCCCCTCCCCCGGCAGCACCCCCGGCTTCTGCAGGAGCAGGGAACCTTCTGGTG
GACGTCTTCGATGGCCCGGCCGCCCAGCCCAGCCTGGGGCCCACCCCCGAGGAGGCCTTCCTCAGCCCAGGTCCTGAGGACATCGGCCCT
CCCATTCCGGAAGCCGATGAGTTGCTGAATAAGTTTGTGTGTAAGAACAACGGGGTCCTGTTCGAGAACCAGCTGCTGCAGATCGGAGTC
AAGTCAGAGTTCCGACAGAACCTGGGCCGCATGTATCTCTTCTATGGCAACAAGACCTCGGTGCAGTTCCAGAATTTCTCACCCACTGTG
GTTCACCCGGGAGACCTCCAGACTCAGCTGGCTGTGCAGACCAAGCGCGTGGCGGCGCAGGTGGACGGCGGCGCGCAGGTGCAGCAGGTG
CTCAATATCGAGTGCCTGCGGGACTTCCTGACGCCCCCGCTGCTGTCCGTGCGCTTCCGGTACGGTGGCGCCCCCCAGGCCCTCACCCTG
AAGCTCCCAGTGACCATCAACAAGTTCTTCCAGCCCACCGAGATGGCGGCCCAGGATTTCTTCCAGCGCTGGAAGCAGCTGAGCCTCCCT
CAACAGGAGGCGCAGAAAATCTTCAAAGCCAACCACCCCATGGACGCAGAAGTTACTAAGGCCAAGCTTCTGGGGTTTGGCTCTGCTCTC
CTGGACAATGTGGACCCCAACCCTGAGAACTTCGTGGGGGCGGGGATCATCCAGACTAAAGCCCTGCAGGTGGGCTGTCTGCTTCGGCTG
GAGCCCAATGCCCAGGCCCAGATGTACCGGCTGACCCTGCGCACCAGCAAGGAGCCCGTCTCCCGTCACCTGTGTGAGCTGCTGGCACAG
CAGTTCTGAGCCCTGGACTCTGCCCCGGGGGATGTGGCCGGCACTGGGCAGCCCCTTGGACTGAGGCAGTTTTGGTGGATGGGGGACCTC
CACTGGTGACAGAGAAGACACCAGGGTTTGGGGGATGCCTGGGACTTTCCTCCGGCCTTTTGTATTTTTATTTTTGTTCATCTGCTGCTG
TTTACATTCTGGGGGGTTAGGGGGAGTCCCCCTCCCTCCCTTTCCCCCCCAAGCACAGAGGGGAGAGGGGCCAGGGAAGTGGATGTCTCC
TCCCCTCCCACCCCACCCTGTTGTAGCCCCTCCTACCCCCTCCCCATCCAGGGGCTGTGTATTATTGTGAGCGAATAAACAGAGAGACGC

>102327_102327_1_ZNF544-AP2A1_ZNF544_chr19_58758160_ENST00000269829_AP2A1_chr19_50285014_ENST00000354293_length(amino acids)=1048AA_BP=115
MERLKRPVQSPTVADWSSEDLCPLHSGLFRCREEMEARSMLVPPQASVCFEDVAMAFTQEEWEQLDLAQRTLYREVTLETWEHIVSLGLF
LSKSDVISQLEQEEDLCRAEQEAPRGKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNK
YTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYK
ASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQC
YPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLA
SSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTIL
NLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVAT
RALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAGSA
LDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSPGPEDIGPPIPE
ADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIE
CLRDFLTPPLLSVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMDAEVTKAKLLGFGSALLDNV

--------------------------------------------------------------
>102327_102327_2_ZNF544-AP2A1_ZNF544_chr19_58758160_ENST00000333581_AP2A1_chr19_50285014_ENST00000354293_length(transcript)=3633nt_BP=478nt
CAGGTGGCAGCCAAGAGCCTCCTGGCACAGCGGCACCAGGCAGGTGACGCCTATTGGACCCCAGAGGTCATCCCAGCTCCAGACGTGGAC
ACATTTTCTTCCAATGATGTCTACGGATGAGGAAACTGAGGCCTGGAGAGGTTAAAGAGACCCGTTCAGAGTCCTACAGTGGCAGACTGG
TCTTCTGAGGACCTCTGCCCTCTACACAGCGGCCTCTTCAGGTGCAGGGAGGAAATGGAAGCACGTTCTATGCTGGTTCCACCCCAGGCA
TCTGTGTGCTTCGAGGATGTGGCTATGGCATTCACACAGGAGGAGTGGGAACAGCTGGACCTGGCCCAGAGGACACTGTACCGAGAGGTG
ACACTGGAGACCTGGGAGCATATTGTCTCCCTGGGGCTTTTCCTTTCCAAATCTGATGTGATCTCTCAGCTGGAGCAAGAAGAGGACCTG
TGCAGGGCAGAGCAGGAGGCCCCCCGAGGTAAGAGCAAAGAGGCGGAAATTAAGAGAATCAACAAGGAACTGGCCAACATCCGCTCCAAG
TTCAAAGGAGACAAAGCCTTGGATGGCTACAGTAAGAAAAAATATGTGTGTAAACTGCTTTTCATCTTCCTGCTTGGCCATGACATTGAC
TTTGGGCACATGGAGGCTGTGAATCTGTTGAGTTCCAATAAATACACAGAGAAGCAAATAGGTTACCTGTTCATTTCTGTGCTGGTGAAC
TCGAACTCGGAGCTGATCCGCCTCATCAACAACGCCATCAAGAATGACCTGGCCAGCCGCAACCCCACCTTCATGTGCCTGGCCCTGCAC
TGCATCGCCAACGTGGGCAGCCGGGAGATGGGCGAGGCCTTTGCCGCTGACATCCCCCGCATCCTGGTGGCCGGGGACAGCATGGACAGT
GTCAAGCAGAGTGCGGCCCTGTGCCTCCTTCGACTGTACAAGGCCTCGCCTGACCTGGTGCCCATGGGCGAGTGGACGGCGCGTGTGGTA
CACCTGCTCAATGACCAGCACATGGGTGTGGTCACGGCCGCCGTCAGCCTCATCACCTGTCTCTGCAAGAAGAACCCAGATGACTTCAAG
ACGTGCGTCTCTCTGGCTGTGTCGCGCCTGAGCCGGATCGTCTCCTCTGCCTCCACCGACCTCCAGGACTACACCTACTACTTCGTCCCA
GCACCCTGGCTCTCGGTGAAGCTCCTGCGGCTGCTGCAGTGCTACCCGCCTCCAGAGGATGCGGCTGTGAAGGGGCGGCTGGTGGAATGT
CTGGAGACTGTGCTCAACAAGGCCCAGGAGCCCCCCAAATCCAAGAAGGTGCAGCATTCCAACGCCAAGAACGCCATCCTCTTCGAGACC
ATCAGCCTCATCATCCACTATGACAGTGAGCCCAACCTCCTGGTTCGGGCCTGCAACCAGCTGGGCCAGTTCCTGCAGCACCGGGAGACC
AACCTGCGCTACCTGGCCCTGGAGAGCATGTGCACGCTGGCCAGCTCCGAGTTCTCCCATGAAGCCGTCAAGACGCACATTGACACCGTC
ATCAATGCCCTCAAGACGGAGCGGGACGTCAGCGTGCGGCAGCGGGCGGCTGACCTCCTCTACGCCATGTGTGACCGGAGCAATGCCAAG
CAGATCGTGTCGGAGATGCTGCGGTACCTGGAGACGGCAGACTACGCCATCCGCGAGGAGATCGTCCTGAAGGTGGCCATCCTGGCCGAG
AAGTACGCCGTGGACTACAGCTGGTACGTGGACACCATCCTCAACCTCATCCGCATTGCGGGCGACTACGTGAGTGAGGAGGTGTGGTAC
CGTGTGCTACAGATCGTCACCAACCGTGATGACGTCCAGGGCTATGCCGCCAAGACCGTCTTTGAGGCGCTCCAGGCCCCTGCCTGTCAC
GAGAACATGGTGAAGGTTGGCGGCTACATCCTTGGGGAGTTTGGGAACCTGATTGCTGGGGACCCCCGCTCCAGCCCCCCAGTGCAGTTC
TCCCTGCTCCACTCCAAGTTCCATCTGTGCAGCGTGGCCACGCGGGCGCTGCTGCTGTCCACCTACATCAAGTTCATCAACCTCTTCCCC
GAGACCAAGGCCACCATCCAGGGCGTCCTGCGGGCCGGCTCCCAGCTGCGCAATGCTGACGTGGAGCTGCAGCAGCGAGCCGTGGAGTAC
CTCACCCTCAGCTCAGTGGCCAGCACCGACGTCCTGGCCACGGTGCTGGAGGAGATGCCGCCCTTCCCCGAGCGCGAGTCGTCCATCCTG
GCCAAGCTGAAACGCAAGAAGGGGCCAGGGGCCGGCAGCGCCCTGGACGATGGCCGGAGGGACCCCAGCAGCAACGACATCAACGGGGGC
ATGGAGCCCACCCCCAGCACTGTGTCGACGCCCTCGCCCTCCGCCGACCTCCTGGGGCTGCGGGCAGCCCCTCCCCCGGCAGCACCCCCG
GCTTCTGCAGGAGCAGGGAACCTTCTGGTGGACGTCTTCGATGGCCCGGCCGCCCAGCCCAGCCTGGGGCCCACCCCCGAGGAGGCCTTC
CTCAGCCCAGGTCCTGAGGACATCGGCCCTCCCATTCCGGAAGCCGATGAGTTGCTGAATAAGTTTGTGTGTAAGAACAACGGGGTCCTG
TTCGAGAACCAGCTGCTGCAGATCGGAGTCAAGTCAGAGTTCCGACAGAACCTGGGCCGCATGTATCTCTTCTATGGCAACAAGACCTCG
GTGCAGTTCCAGAATTTCTCACCCACTGTGGTTCACCCGGGAGACCTCCAGACTCAGCTGGCTGTGCAGACCAAGCGCGTGGCGGCGCAG
GTGGACGGCGGCGCGCAGGTGCAGCAGGTGCTCAATATCGAGTGCCTGCGGGACTTCCTGACGCCCCCGCTGCTGTCCGTGCGCTTCCGG
TACGGTGGCGCCCCCCAGGCCCTCACCCTGAAGCTCCCAGTGACCATCAACAAGTTCTTCCAGCCCACCGAGATGGCGGCCCAGGATTTC
TTCCAGCGCTGGAAGCAGCTGAGCCTCCCTCAACAGGAGGCGCAGAAAATCTTCAAAGCCAACCACCCCATGGACGCAGAAGTTACTAAG
GCCAAGCTTCTGGGGTTTGGCTCTGCTCTCCTGGACAATGTGGACCCCAACCCTGAGAACTTCGTGGGGGCGGGGATCATCCAGACTAAA
GCCCTGCAGGTGGGCTGTCTGCTTCGGCTGGAGCCCAATGCCCAGGCCCAGATGTACCGGCTGACCCTGCGCACCAGCAAGGAGCCCGTC
TCCCGTCACCTGTGTGAGCTGCTGGCACAGCAGTTCTGAGCCCTGGACTCTGCCCCGGGGGATGTGGCCGGCACTGGGCAGCCCCTTGGA
CTGAGGCAGTTTTGGTGGATGGGGGACCTCCACTGGTGACAGAGAAGACACCAGGGTTTGGGGGATGCCTGGGACTTTCCTCCGGCCTTT
TGTATTTTTATTTTTGTTCATCTGCTGCTGTTTACATTCTGGGGGGTTAGGGGGAGTCCCCCTCCCTCCCTTTCCCCCCCAAGCACAGAG
GGGAGAGGGGCCAGGGAAGTGGATGTCTCCTCCCCTCCCACCCCACCCTGTTGTAGCCCCTCCTACCCCCTCCCCATCCAGGGGCTGTGT

>102327_102327_2_ZNF544-AP2A1_ZNF544_chr19_58758160_ENST00000333581_AP2A1_chr19_50285014_ENST00000354293_length(amino acids)=1048AA_BP=115
MERLKRPVQSPTVADWSSEDLCPLHSGLFRCREEMEARSMLVPPQASVCFEDVAMAFTQEEWEQLDLAQRTLYREVTLETWEHIVSLGLF
LSKSDVISQLEQEEDLCRAEQEAPRGKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNK
YTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYK
ASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQC
YPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLA
SSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTIL
NLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVAT
RALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAGSA
LDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSPGPEDIGPPIPE
ADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIE
CLRDFLTPPLLSVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMDAEVTKAKLLGFGSALLDNV

--------------------------------------------------------------
>102327_102327_3_ZNF544-AP2A1_ZNF544_chr19_58758160_ENST00000595981_AP2A1_chr19_50285014_ENST00000354293_length(transcript)=3630nt_BP=475nt
GTGGCAGCCAAGAGCCTCCTGGCACAGCGGCACCAGGCAGGTGACGCCTATTGGACCCCAGAGGTCATCCCAGCTCCAGACGTGGACACA
TTTTCTTCCAATGATGTCTACGGATGAGGAAACTGAGGCCTGGAGAGGTTAAAGAGACCCGTTCAGAGTCCTACAGTGGCAGACTGGTCT
TCTGAGGACCTCTGCCCTCTACACAGCGGCCTCTTCAGGTGCAGGGAGGAAATGGAAGCACGTTCTATGCTGGTTCCACCCCAGGCATCT
GTGTGCTTCGAGGATGTGGCTATGGCATTCACACAGGAGGAGTGGGAACAGCTGGACCTGGCCCAGAGGACACTGTACCGAGAGGTGACA
CTGGAGACCTGGGAGCATATTGTCTCCCTGGGGCTTTTCCTTTCCAAATCTGATGTGATCTCTCAGCTGGAGCAAGAAGAGGACCTGTGC
AGGGCAGAGCAGGAGGCCCCCCGAGGTAAGAGCAAAGAGGCGGAAATTAAGAGAATCAACAAGGAACTGGCCAACATCCGCTCCAAGTTC
AAAGGAGACAAAGCCTTGGATGGCTACAGTAAGAAAAAATATGTGTGTAAACTGCTTTTCATCTTCCTGCTTGGCCATGACATTGACTTT
GGGCACATGGAGGCTGTGAATCTGTTGAGTTCCAATAAATACACAGAGAAGCAAATAGGTTACCTGTTCATTTCTGTGCTGGTGAACTCG
AACTCGGAGCTGATCCGCCTCATCAACAACGCCATCAAGAATGACCTGGCCAGCCGCAACCCCACCTTCATGTGCCTGGCCCTGCACTGC
ATCGCCAACGTGGGCAGCCGGGAGATGGGCGAGGCCTTTGCCGCTGACATCCCCCGCATCCTGGTGGCCGGGGACAGCATGGACAGTGTC
AAGCAGAGTGCGGCCCTGTGCCTCCTTCGACTGTACAAGGCCTCGCCTGACCTGGTGCCCATGGGCGAGTGGACGGCGCGTGTGGTACAC
CTGCTCAATGACCAGCACATGGGTGTGGTCACGGCCGCCGTCAGCCTCATCACCTGTCTCTGCAAGAAGAACCCAGATGACTTCAAGACG
TGCGTCTCTCTGGCTGTGTCGCGCCTGAGCCGGATCGTCTCCTCTGCCTCCACCGACCTCCAGGACTACACCTACTACTTCGTCCCAGCA
CCCTGGCTCTCGGTGAAGCTCCTGCGGCTGCTGCAGTGCTACCCGCCTCCAGAGGATGCGGCTGTGAAGGGGCGGCTGGTGGAATGTCTG
GAGACTGTGCTCAACAAGGCCCAGGAGCCCCCCAAATCCAAGAAGGTGCAGCATTCCAACGCCAAGAACGCCATCCTCTTCGAGACCATC
AGCCTCATCATCCACTATGACAGTGAGCCCAACCTCCTGGTTCGGGCCTGCAACCAGCTGGGCCAGTTCCTGCAGCACCGGGAGACCAAC
CTGCGCTACCTGGCCCTGGAGAGCATGTGCACGCTGGCCAGCTCCGAGTTCTCCCATGAAGCCGTCAAGACGCACATTGACACCGTCATC
AATGCCCTCAAGACGGAGCGGGACGTCAGCGTGCGGCAGCGGGCGGCTGACCTCCTCTACGCCATGTGTGACCGGAGCAATGCCAAGCAG
ATCGTGTCGGAGATGCTGCGGTACCTGGAGACGGCAGACTACGCCATCCGCGAGGAGATCGTCCTGAAGGTGGCCATCCTGGCCGAGAAG
TACGCCGTGGACTACAGCTGGTACGTGGACACCATCCTCAACCTCATCCGCATTGCGGGCGACTACGTGAGTGAGGAGGTGTGGTACCGT
GTGCTACAGATCGTCACCAACCGTGATGACGTCCAGGGCTATGCCGCCAAGACCGTCTTTGAGGCGCTCCAGGCCCCTGCCTGTCACGAG
AACATGGTGAAGGTTGGCGGCTACATCCTTGGGGAGTTTGGGAACCTGATTGCTGGGGACCCCCGCTCCAGCCCCCCAGTGCAGTTCTCC
CTGCTCCACTCCAAGTTCCATCTGTGCAGCGTGGCCACGCGGGCGCTGCTGCTGTCCACCTACATCAAGTTCATCAACCTCTTCCCCGAG
ACCAAGGCCACCATCCAGGGCGTCCTGCGGGCCGGCTCCCAGCTGCGCAATGCTGACGTGGAGCTGCAGCAGCGAGCCGTGGAGTACCTC
ACCCTCAGCTCAGTGGCCAGCACCGACGTCCTGGCCACGGTGCTGGAGGAGATGCCGCCCTTCCCCGAGCGCGAGTCGTCCATCCTGGCC
AAGCTGAAACGCAAGAAGGGGCCAGGGGCCGGCAGCGCCCTGGACGATGGCCGGAGGGACCCCAGCAGCAACGACATCAACGGGGGCATG
GAGCCCACCCCCAGCACTGTGTCGACGCCCTCGCCCTCCGCCGACCTCCTGGGGCTGCGGGCAGCCCCTCCCCCGGCAGCACCCCCGGCT
TCTGCAGGAGCAGGGAACCTTCTGGTGGACGTCTTCGATGGCCCGGCCGCCCAGCCCAGCCTGGGGCCCACCCCCGAGGAGGCCTTCCTC
AGCCCAGGTCCTGAGGACATCGGCCCTCCCATTCCGGAAGCCGATGAGTTGCTGAATAAGTTTGTGTGTAAGAACAACGGGGTCCTGTTC
GAGAACCAGCTGCTGCAGATCGGAGTCAAGTCAGAGTTCCGACAGAACCTGGGCCGCATGTATCTCTTCTATGGCAACAAGACCTCGGTG
CAGTTCCAGAATTTCTCACCCACTGTGGTTCACCCGGGAGACCTCCAGACTCAGCTGGCTGTGCAGACCAAGCGCGTGGCGGCGCAGGTG
GACGGCGGCGCGCAGGTGCAGCAGGTGCTCAATATCGAGTGCCTGCGGGACTTCCTGACGCCCCCGCTGCTGTCCGTGCGCTTCCGGTAC
GGTGGCGCCCCCCAGGCCCTCACCCTGAAGCTCCCAGTGACCATCAACAAGTTCTTCCAGCCCACCGAGATGGCGGCCCAGGATTTCTTC
CAGCGCTGGAAGCAGCTGAGCCTCCCTCAACAGGAGGCGCAGAAAATCTTCAAAGCCAACCACCCCATGGACGCAGAAGTTACTAAGGCC
AAGCTTCTGGGGTTTGGCTCTGCTCTCCTGGACAATGTGGACCCCAACCCTGAGAACTTCGTGGGGGCGGGGATCATCCAGACTAAAGCC
CTGCAGGTGGGCTGTCTGCTTCGGCTGGAGCCCAATGCCCAGGCCCAGATGTACCGGCTGACCCTGCGCACCAGCAAGGAGCCCGTCTCC
CGTCACCTGTGTGAGCTGCTGGCACAGCAGTTCTGAGCCCTGGACTCTGCCCCGGGGGATGTGGCCGGCACTGGGCAGCCCCTTGGACTG
AGGCAGTTTTGGTGGATGGGGGACCTCCACTGGTGACAGAGAAGACACCAGGGTTTGGGGGATGCCTGGGACTTTCCTCCGGCCTTTTGT
ATTTTTATTTTTGTTCATCTGCTGCTGTTTACATTCTGGGGGGTTAGGGGGAGTCCCCCTCCCTCCCTTTCCCCCCCAAGCACAGAGGGG
AGAGGGGCCAGGGAAGTGGATGTCTCCTCCCCTCCCACCCCACCCTGTTGTAGCCCCTCCTACCCCCTCCCCATCCAGGGGCTGTGTATT

>102327_102327_3_ZNF544-AP2A1_ZNF544_chr19_58758160_ENST00000595981_AP2A1_chr19_50285014_ENST00000354293_length(amino acids)=1048AA_BP=115
MERLKRPVQSPTVADWSSEDLCPLHSGLFRCREEMEARSMLVPPQASVCFEDVAMAFTQEEWEQLDLAQRTLYREVTLETWEHIVSLGLF
LSKSDVISQLEQEEDLCRAEQEAPRGKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNK
YTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYK
ASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQC
YPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLA
SSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTIL
NLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVAT
RALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAGSA
LDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSPGPEDIGPPIPE
ADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIE
CLRDFLTPPLLSVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMDAEVTKAKLLGFGSALLDNV

--------------------------------------------------------------
>102327_102327_4_ZNF544-AP2A1_ZNF544_chr19_58758160_ENST00000596652_AP2A1_chr19_50285014_ENST00000354293_length(transcript)=3633nt_BP=478nt
CAGGTGGCAGCCAAGAGCCTCCTGGCACAGCGGCACCAGGCAGGTGACGCCTATTGGACCCCAGAGGTCATCCCAGCTCCAGACGTGGAC
ACATTTTCTTCCAATGATGTCTACGGATGAGGAAACTGAGGCCTGGAGAGGTTAAAGAGACCCGTTCAGAGTCCTACAGTGGCAGACTGG
TCTTCTGAGGACCTCTGCCCTCTACACAGCGGCCTCTTCAGGTGCAGGGAGGAAATGGAAGCACGTTCTATGCTGGTTCCACCCCAGGCA
TCTGTGTGCTTCGAGGATGTGGCTATGGCATTCACACAGGAGGAGTGGGAACAGCTGGACCTGGCCCAGAGGACACTGTACCGAGAGGTG
ACACTGGAGACCTGGGAGCATATTGTCTCCCTGGGGCTTTTCCTTTCCAAATCTGATGTGATCTCTCAGCTGGAGCAAGAAGAGGACCTG
TGCAGGGCAGAGCAGGAGGCCCCCCGAGGTAAGAGCAAAGAGGCGGAAATTAAGAGAATCAACAAGGAACTGGCCAACATCCGCTCCAAG
TTCAAAGGAGACAAAGCCTTGGATGGCTACAGTAAGAAAAAATATGTGTGTAAACTGCTTTTCATCTTCCTGCTTGGCCATGACATTGAC
TTTGGGCACATGGAGGCTGTGAATCTGTTGAGTTCCAATAAATACACAGAGAAGCAAATAGGTTACCTGTTCATTTCTGTGCTGGTGAAC
TCGAACTCGGAGCTGATCCGCCTCATCAACAACGCCATCAAGAATGACCTGGCCAGCCGCAACCCCACCTTCATGTGCCTGGCCCTGCAC
TGCATCGCCAACGTGGGCAGCCGGGAGATGGGCGAGGCCTTTGCCGCTGACATCCCCCGCATCCTGGTGGCCGGGGACAGCATGGACAGT
GTCAAGCAGAGTGCGGCCCTGTGCCTCCTTCGACTGTACAAGGCCTCGCCTGACCTGGTGCCCATGGGCGAGTGGACGGCGCGTGTGGTA
CACCTGCTCAATGACCAGCACATGGGTGTGGTCACGGCCGCCGTCAGCCTCATCACCTGTCTCTGCAAGAAGAACCCAGATGACTTCAAG
ACGTGCGTCTCTCTGGCTGTGTCGCGCCTGAGCCGGATCGTCTCCTCTGCCTCCACCGACCTCCAGGACTACACCTACTACTTCGTCCCA
GCACCCTGGCTCTCGGTGAAGCTCCTGCGGCTGCTGCAGTGCTACCCGCCTCCAGAGGATGCGGCTGTGAAGGGGCGGCTGGTGGAATGT
CTGGAGACTGTGCTCAACAAGGCCCAGGAGCCCCCCAAATCCAAGAAGGTGCAGCATTCCAACGCCAAGAACGCCATCCTCTTCGAGACC
ATCAGCCTCATCATCCACTATGACAGTGAGCCCAACCTCCTGGTTCGGGCCTGCAACCAGCTGGGCCAGTTCCTGCAGCACCGGGAGACC
AACCTGCGCTACCTGGCCCTGGAGAGCATGTGCACGCTGGCCAGCTCCGAGTTCTCCCATGAAGCCGTCAAGACGCACATTGACACCGTC
ATCAATGCCCTCAAGACGGAGCGGGACGTCAGCGTGCGGCAGCGGGCGGCTGACCTCCTCTACGCCATGTGTGACCGGAGCAATGCCAAG
CAGATCGTGTCGGAGATGCTGCGGTACCTGGAGACGGCAGACTACGCCATCCGCGAGGAGATCGTCCTGAAGGTGGCCATCCTGGCCGAG
AAGTACGCCGTGGACTACAGCTGGTACGTGGACACCATCCTCAACCTCATCCGCATTGCGGGCGACTACGTGAGTGAGGAGGTGTGGTAC
CGTGTGCTACAGATCGTCACCAACCGTGATGACGTCCAGGGCTATGCCGCCAAGACCGTCTTTGAGGCGCTCCAGGCCCCTGCCTGTCAC
GAGAACATGGTGAAGGTTGGCGGCTACATCCTTGGGGAGTTTGGGAACCTGATTGCTGGGGACCCCCGCTCCAGCCCCCCAGTGCAGTTC
TCCCTGCTCCACTCCAAGTTCCATCTGTGCAGCGTGGCCACGCGGGCGCTGCTGCTGTCCACCTACATCAAGTTCATCAACCTCTTCCCC
GAGACCAAGGCCACCATCCAGGGCGTCCTGCGGGCCGGCTCCCAGCTGCGCAATGCTGACGTGGAGCTGCAGCAGCGAGCCGTGGAGTAC
CTCACCCTCAGCTCAGTGGCCAGCACCGACGTCCTGGCCACGGTGCTGGAGGAGATGCCGCCCTTCCCCGAGCGCGAGTCGTCCATCCTG
GCCAAGCTGAAACGCAAGAAGGGGCCAGGGGCCGGCAGCGCCCTGGACGATGGCCGGAGGGACCCCAGCAGCAACGACATCAACGGGGGC
ATGGAGCCCACCCCCAGCACTGTGTCGACGCCCTCGCCCTCCGCCGACCTCCTGGGGCTGCGGGCAGCCCCTCCCCCGGCAGCACCCCCG
GCTTCTGCAGGAGCAGGGAACCTTCTGGTGGACGTCTTCGATGGCCCGGCCGCCCAGCCCAGCCTGGGGCCCACCCCCGAGGAGGCCTTC
CTCAGCCCAGGTCCTGAGGACATCGGCCCTCCCATTCCGGAAGCCGATGAGTTGCTGAATAAGTTTGTGTGTAAGAACAACGGGGTCCTG
TTCGAGAACCAGCTGCTGCAGATCGGAGTCAAGTCAGAGTTCCGACAGAACCTGGGCCGCATGTATCTCTTCTATGGCAACAAGACCTCG
GTGCAGTTCCAGAATTTCTCACCCACTGTGGTTCACCCGGGAGACCTCCAGACTCAGCTGGCTGTGCAGACCAAGCGCGTGGCGGCGCAG
GTGGACGGCGGCGCGCAGGTGCAGCAGGTGCTCAATATCGAGTGCCTGCGGGACTTCCTGACGCCCCCGCTGCTGTCCGTGCGCTTCCGG
TACGGTGGCGCCCCCCAGGCCCTCACCCTGAAGCTCCCAGTGACCATCAACAAGTTCTTCCAGCCCACCGAGATGGCGGCCCAGGATTTC
TTCCAGCGCTGGAAGCAGCTGAGCCTCCCTCAACAGGAGGCGCAGAAAATCTTCAAAGCCAACCACCCCATGGACGCAGAAGTTACTAAG
GCCAAGCTTCTGGGGTTTGGCTCTGCTCTCCTGGACAATGTGGACCCCAACCCTGAGAACTTCGTGGGGGCGGGGATCATCCAGACTAAA
GCCCTGCAGGTGGGCTGTCTGCTTCGGCTGGAGCCCAATGCCCAGGCCCAGATGTACCGGCTGACCCTGCGCACCAGCAAGGAGCCCGTC
TCCCGTCACCTGTGTGAGCTGCTGGCACAGCAGTTCTGAGCCCTGGACTCTGCCCCGGGGGATGTGGCCGGCACTGGGCAGCCCCTTGGA
CTGAGGCAGTTTTGGTGGATGGGGGACCTCCACTGGTGACAGAGAAGACACCAGGGTTTGGGGGATGCCTGGGACTTTCCTCCGGCCTTT
TGTATTTTTATTTTTGTTCATCTGCTGCTGTTTACATTCTGGGGGGTTAGGGGGAGTCCCCCTCCCTCCCTTTCCCCCCCAAGCACAGAG
GGGAGAGGGGCCAGGGAAGTGGATGTCTCCTCCCCTCCCACCCCACCCTGTTGTAGCCCCTCCTACCCCCTCCCCATCCAGGGGCTGTGT

>102327_102327_4_ZNF544-AP2A1_ZNF544_chr19_58758160_ENST00000596652_AP2A1_chr19_50285014_ENST00000354293_length(amino acids)=1048AA_BP=115
MERLKRPVQSPTVADWSSEDLCPLHSGLFRCREEMEARSMLVPPQASVCFEDVAMAFTQEEWEQLDLAQRTLYREVTLETWEHIVSLGLF
LSKSDVISQLEQEEDLCRAEQEAPRGKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNK
YTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYK
ASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQC
YPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLA
SSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTIL
NLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVAT
RALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAGSA
LDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSPGPEDIGPPIPE
ADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIE
CLRDFLTPPLLSVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMDAEVTKAKLLGFGSALLDNV

--------------------------------------------------------------
>102327_102327_5_ZNF544-AP2A1_ZNF544_chr19_58758160_ENST00000596929_AP2A1_chr19_50285014_ENST00000354293_length(transcript)=3633nt_BP=478nt
CAGGTGGCAGCCAAGAGCCTCCTGGCACAGCGGCACCAGGCAGGTGACGCCTATTGGACCCCAGAGGTCATCCCAGCTCCAGACGTGGAC
ACATTTTCTTCCAATGATGTCTACGGATGAGGAAACTGAGGCCTGGAGAGGTTAAAGAGACCCGTTCAGAGTCCTACAGTGGCAGACTGG
TCTTCTGAGGACCTCTGCCCTCTACACAGCGGCCTCTTCAGGTGCAGGGAGGAAATGGAAGCACGTTCTATGCTGGTTCCACCCCAGGCA
TCTGTGTGCTTCGAGGATGTGGCTATGGCATTCACACAGGAGGAGTGGGAACAGCTGGACCTGGCCCAGAGGACACTGTACCGAGAGGTG
ACACTGGAGACCTGGGAGCATATTGTCTCCCTGGGGCTTTTCCTTTCCAAATCTGATGTGATCTCTCAGCTGGAGCAAGAAGAGGACCTG
TGCAGGGCAGAGCAGGAGGCCCCCCGAGGTAAGAGCAAAGAGGCGGAAATTAAGAGAATCAACAAGGAACTGGCCAACATCCGCTCCAAG
TTCAAAGGAGACAAAGCCTTGGATGGCTACAGTAAGAAAAAATATGTGTGTAAACTGCTTTTCATCTTCCTGCTTGGCCATGACATTGAC
TTTGGGCACATGGAGGCTGTGAATCTGTTGAGTTCCAATAAATACACAGAGAAGCAAATAGGTTACCTGTTCATTTCTGTGCTGGTGAAC
TCGAACTCGGAGCTGATCCGCCTCATCAACAACGCCATCAAGAATGACCTGGCCAGCCGCAACCCCACCTTCATGTGCCTGGCCCTGCAC
TGCATCGCCAACGTGGGCAGCCGGGAGATGGGCGAGGCCTTTGCCGCTGACATCCCCCGCATCCTGGTGGCCGGGGACAGCATGGACAGT
GTCAAGCAGAGTGCGGCCCTGTGCCTCCTTCGACTGTACAAGGCCTCGCCTGACCTGGTGCCCATGGGCGAGTGGACGGCGCGTGTGGTA
CACCTGCTCAATGACCAGCACATGGGTGTGGTCACGGCCGCCGTCAGCCTCATCACCTGTCTCTGCAAGAAGAACCCAGATGACTTCAAG
ACGTGCGTCTCTCTGGCTGTGTCGCGCCTGAGCCGGATCGTCTCCTCTGCCTCCACCGACCTCCAGGACTACACCTACTACTTCGTCCCA
GCACCCTGGCTCTCGGTGAAGCTCCTGCGGCTGCTGCAGTGCTACCCGCCTCCAGAGGATGCGGCTGTGAAGGGGCGGCTGGTGGAATGT
CTGGAGACTGTGCTCAACAAGGCCCAGGAGCCCCCCAAATCCAAGAAGGTGCAGCATTCCAACGCCAAGAACGCCATCCTCTTCGAGACC
ATCAGCCTCATCATCCACTATGACAGTGAGCCCAACCTCCTGGTTCGGGCCTGCAACCAGCTGGGCCAGTTCCTGCAGCACCGGGAGACC
AACCTGCGCTACCTGGCCCTGGAGAGCATGTGCACGCTGGCCAGCTCCGAGTTCTCCCATGAAGCCGTCAAGACGCACATTGACACCGTC
ATCAATGCCCTCAAGACGGAGCGGGACGTCAGCGTGCGGCAGCGGGCGGCTGACCTCCTCTACGCCATGTGTGACCGGAGCAATGCCAAG
CAGATCGTGTCGGAGATGCTGCGGTACCTGGAGACGGCAGACTACGCCATCCGCGAGGAGATCGTCCTGAAGGTGGCCATCCTGGCCGAG
AAGTACGCCGTGGACTACAGCTGGTACGTGGACACCATCCTCAACCTCATCCGCATTGCGGGCGACTACGTGAGTGAGGAGGTGTGGTAC
CGTGTGCTACAGATCGTCACCAACCGTGATGACGTCCAGGGCTATGCCGCCAAGACCGTCTTTGAGGCGCTCCAGGCCCCTGCCTGTCAC
GAGAACATGGTGAAGGTTGGCGGCTACATCCTTGGGGAGTTTGGGAACCTGATTGCTGGGGACCCCCGCTCCAGCCCCCCAGTGCAGTTC
TCCCTGCTCCACTCCAAGTTCCATCTGTGCAGCGTGGCCACGCGGGCGCTGCTGCTGTCCACCTACATCAAGTTCATCAACCTCTTCCCC
GAGACCAAGGCCACCATCCAGGGCGTCCTGCGGGCCGGCTCCCAGCTGCGCAATGCTGACGTGGAGCTGCAGCAGCGAGCCGTGGAGTAC
CTCACCCTCAGCTCAGTGGCCAGCACCGACGTCCTGGCCACGGTGCTGGAGGAGATGCCGCCCTTCCCCGAGCGCGAGTCGTCCATCCTG
GCCAAGCTGAAACGCAAGAAGGGGCCAGGGGCCGGCAGCGCCCTGGACGATGGCCGGAGGGACCCCAGCAGCAACGACATCAACGGGGGC
ATGGAGCCCACCCCCAGCACTGTGTCGACGCCCTCGCCCTCCGCCGACCTCCTGGGGCTGCGGGCAGCCCCTCCCCCGGCAGCACCCCCG
GCTTCTGCAGGAGCAGGGAACCTTCTGGTGGACGTCTTCGATGGCCCGGCCGCCCAGCCCAGCCTGGGGCCCACCCCCGAGGAGGCCTTC
CTCAGCCCAGGTCCTGAGGACATCGGCCCTCCCATTCCGGAAGCCGATGAGTTGCTGAATAAGTTTGTGTGTAAGAACAACGGGGTCCTG
TTCGAGAACCAGCTGCTGCAGATCGGAGTCAAGTCAGAGTTCCGACAGAACCTGGGCCGCATGTATCTCTTCTATGGCAACAAGACCTCG
GTGCAGTTCCAGAATTTCTCACCCACTGTGGTTCACCCGGGAGACCTCCAGACTCAGCTGGCTGTGCAGACCAAGCGCGTGGCGGCGCAG
GTGGACGGCGGCGCGCAGGTGCAGCAGGTGCTCAATATCGAGTGCCTGCGGGACTTCCTGACGCCCCCGCTGCTGTCCGTGCGCTTCCGG
TACGGTGGCGCCCCCCAGGCCCTCACCCTGAAGCTCCCAGTGACCATCAACAAGTTCTTCCAGCCCACCGAGATGGCGGCCCAGGATTTC
TTCCAGCGCTGGAAGCAGCTGAGCCTCCCTCAACAGGAGGCGCAGAAAATCTTCAAAGCCAACCACCCCATGGACGCAGAAGTTACTAAG
GCCAAGCTTCTGGGGTTTGGCTCTGCTCTCCTGGACAATGTGGACCCCAACCCTGAGAACTTCGTGGGGGCGGGGATCATCCAGACTAAA
GCCCTGCAGGTGGGCTGTCTGCTTCGGCTGGAGCCCAATGCCCAGGCCCAGATGTACCGGCTGACCCTGCGCACCAGCAAGGAGCCCGTC
TCCCGTCACCTGTGTGAGCTGCTGGCACAGCAGTTCTGAGCCCTGGACTCTGCCCCGGGGGATGTGGCCGGCACTGGGCAGCCCCTTGGA
CTGAGGCAGTTTTGGTGGATGGGGGACCTCCACTGGTGACAGAGAAGACACCAGGGTTTGGGGGATGCCTGGGACTTTCCTCCGGCCTTT
TGTATTTTTATTTTTGTTCATCTGCTGCTGTTTACATTCTGGGGGGTTAGGGGGAGTCCCCCTCCCTCCCTTTCCCCCCCAAGCACAGAG
GGGAGAGGGGCCAGGGAAGTGGATGTCTCCTCCCCTCCCACCCCACCCTGTTGTAGCCCCTCCTACCCCCTCCCCATCCAGGGGCTGTGT

>102327_102327_5_ZNF544-AP2A1_ZNF544_chr19_58758160_ENST00000596929_AP2A1_chr19_50285014_ENST00000354293_length(amino acids)=1048AA_BP=115
MERLKRPVQSPTVADWSSEDLCPLHSGLFRCREEMEARSMLVPPQASVCFEDVAMAFTQEEWEQLDLAQRTLYREVTLETWEHIVSLGLF
LSKSDVISQLEQEEDLCRAEQEAPRGKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNK
YTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYK
ASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQC
YPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLA
SSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTIL
NLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVAT
RALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAGSA
LDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSPGPEDIGPPIPE
ADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIE
CLRDFLTPPLLSVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMDAEVTKAKLLGFGSALLDNV

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Fusion Gene PPI Analysis for ZNF544-AP2A1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF544-AP2A1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF544-AP2A1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource