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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BRE-ZNF57 (FusionGDB2 ID:10245)

Fusion Gene Summary for BRE-ZNF57

check button Fusion gene summary
Fusion gene informationFusion gene name: BRE-ZNF57
Fusion gene ID: 10245
HgeneTgene
Gene symbol

BRE

ZNF57

Gene ID

9577

126295

Gene nameBRISC and BRCA1 A complex member 2zinc finger protein 57
SynonymsBRCC4|BRCC45|BREZNF424
Cytomap

2p23.2

19p13.3

Type of geneprotein-codingprotein-coding
DescriptionBRISC and BRCA1-A complex member 2BRCA1-A complex subunit BREBRCA1/BRCA2-containing complex subunit 45BRCA1/BRCA2-containing complex, subunit 4brain and reproductive organ-expressed (TNFRSF1A modulator)brain and reproductive organ-expressed proteinzinc finger protein 57zinc finger protein 424
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000603461, ENST00000342045, 
ENST00000344773, ENST00000361704, 
ENST00000379624, ENST00000379632, 
ENST00000306908, ENST00000523428, 
Fusion gene scores* DoF score13 X 9 X 8=9361 X 1 X 1=1
# samples 151
** MAII scorelog2(15/936*10)=-2.64154602908752
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: BRE [Title/Abstract] AND ZNF57 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBRE(28248287)-ZNF57(2915520), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBRE

GO:0043066

negative regulation of apoptotic process

15465831


check buttonFusion gene breakpoints across BRE (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZNF57 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-FS-A1Z4-06ABREchr2

28248287

+ZNF57chr19

2915520

+


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Fusion Gene ORF analysis for BRE-ZNF57

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000603461ENST00000306908BREchr2

28248287

+ZNF57chr19

2915520

+
3UTR-5UTRENST00000603461ENST00000523428BREchr2

28248287

+ZNF57chr19

2915520

+
5CDS-5UTRENST00000342045ENST00000523428BREchr2

28248287

+ZNF57chr19

2915520

+
5CDS-5UTRENST00000344773ENST00000523428BREchr2

28248287

+ZNF57chr19

2915520

+
5CDS-5UTRENST00000361704ENST00000523428BREchr2

28248287

+ZNF57chr19

2915520

+
5CDS-5UTRENST00000379624ENST00000523428BREchr2

28248287

+ZNF57chr19

2915520

+
5CDS-5UTRENST00000379632ENST00000523428BREchr2

28248287

+ZNF57chr19

2915520

+
In-frameENST00000342045ENST00000306908BREchr2

28248287

+ZNF57chr19

2915520

+
In-frameENST00000344773ENST00000306908BREchr2

28248287

+ZNF57chr19

2915520

+
In-frameENST00000361704ENST00000306908BREchr2

28248287

+ZNF57chr19

2915520

+
In-frameENST00000379624ENST00000306908BREchr2

28248287

+ZNF57chr19

2915520

+
In-frameENST00000379632ENST00000306908BREchr2

28248287

+ZNF57chr19

2915520

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000344773BREchr228248287+ENST00000306908ZNF57chr192915520+24856331382297719
ENST00000379624BREchr228248287+ENST00000306908ZNF57chr192915520+24646121172276719
ENST00000342045BREchr228248287+ENST00000306908ZNF57chr192915520+24886361412300719
ENST00000379632BREchr228248287+ENST00000306908ZNF57chr192915520+24876351402299719
ENST00000361704BREchr228248287+ENST00000306908ZNF57chr192915520+2421569742233719

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000344773ENST00000306908BREchr228248287+ZNF57chr192915520+0.0009500930.99904984
ENST00000379624ENST00000306908BREchr228248287+ZNF57chr192915520+0.000933540.99906653
ENST00000342045ENST00000306908BREchr228248287+ZNF57chr192915520+0.0009360390.999064
ENST00000379632ENST00000306908BREchr228248287+ZNF57chr192915520+0.0009379630.999062
ENST00000361704ENST00000306908BREchr228248287+ZNF57chr192915520+0.0009568130.99904317

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Fusion Genomic Features for BRE-ZNF57


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BREchr228248287+ZNF57chr192915519+5.95E-060.99999404
BREchr228248287+ZNF57chr192915519+5.95E-060.99999404

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for BRE-ZNF57


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:28248287/chr19:2915520)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBREchr2:28248287chr19:2915520ENST00000342045+61330_147165384.0RegionNote=UEV-like 1
HgeneBREchr2:28248287chr19:2915520ENST00000344773+51330_147165528.6666666666666RegionNote=UEV-like 1
HgeneBREchr2:28248287chr19:2915520ENST00000361704+51330_147165511.0RegionNote=UEV-like 1
HgeneBREchr2:28248287chr19:2915520ENST00000379624+51230_147165384.0RegionNote=UEV-like 1
HgeneBREchr2:28248287chr19:2915520ENST00000379632+61430_147165511.0RegionNote=UEV-like 1
TgeneZNF57chr2:28248287chr19:2915520ENST00000306908044_761556.0DomainKRAB
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804140_1621556.0Zinc fingerC2H2-type 1
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804196_2181556.0Zinc fingerC2H2-type 2%3B degenerate
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804224_2461556.0Zinc fingerC2H2-type 3
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804252_2741556.0Zinc fingerC2H2-type 4
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804280_3021556.0Zinc fingerC2H2-type 5
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804308_3301556.0Zinc fingerC2H2-type 6
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804336_3581556.0Zinc fingerC2H2-type 7
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804364_3861556.0Zinc fingerC2H2-type 8
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804392_4141556.0Zinc fingerC2H2-type 9
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804420_4421556.0Zinc fingerC2H2-type 10
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804448_4701556.0Zinc fingerC2H2-type 11
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804476_4981556.0Zinc fingerC2H2-type 12
TgeneZNF57chr2:28248287chr19:2915520ENST0000030690804504_5261556.0Zinc fingerC2H2-type 13

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBREchr2:28248287chr19:2915520ENST00000342045+613275_364165384.0RegionNote=UEV-like 2
HgeneBREchr2:28248287chr19:2915520ENST00000344773+513275_364165528.6666666666666RegionNote=UEV-like 2
HgeneBREchr2:28248287chr19:2915520ENST00000361704+513275_364165511.0RegionNote=UEV-like 2
HgeneBREchr2:28248287chr19:2915520ENST00000379624+512275_364165384.0RegionNote=UEV-like 2
HgeneBREchr2:28248287chr19:2915520ENST00000379632+614275_364165511.0RegionNote=UEV-like 2


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Fusion Gene Sequence for BRE-ZNF57


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>10245_10245_1_BRE-ZNF57_BRE_chr2_28248287_ENST00000342045_ZNF57_chr19_2915520_ENST00000306908_length(transcript)=2488nt_BP=636nt
GGGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTCCAGAAGCAAGAGATAAAGTAATAATGGGTACTGTGGGGAAAA
ACACAGAAGAACAATTCGGTAATATAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATG
CTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGC
TGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTGGGATATCATTTTC
AATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTTGCAGAATCTTGCC
TCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATGTAGCCGCCTCCGG
GAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGCTGGGAAAAAAAAC
AACTGGGACTCAGTGGTCTTTGAGGATGTGGCTGTGGACTTCACCCTGGAGGAGTGGGCTTTGCTGGATTCTGCTCAGAGGGACCTCTAC
AGAGATGTGATGCTGGAGACCTTCCGGAACCTGGCCTCAGTAGATGATGGGACTCAATTTAAAGCCAATGGGTCAGTTTCTCTGCAGGAT
ATGTACGGGCAAGAAAAATCTAAGGAACAGACAATACCAAACTTCACAGGAAATAATTCCTGTGCCTACACTTTAGAAAAAAATTGTGAA
GGCTATGGCACTGAAGACCACCACAAAAATCTGAGAAATCATATGGTGGACAGATTCTGTACACATAATGAAGGTAATCAATATGGAGAA
GCCATCCATCAAATGCCAGATCTTACCCTGCACAAGAAAGTTTCTGCTGGAGAAAAACCATATGAATGCACCAAGTGCAGGACAGTCTTC
ACGCATCTTTCTTCTCTTAAAAGGCACGTCAAGTCTCACTGTGGACGAAAAGCACCTCCAGGTGAGGAATGTAAGCAGGCCTGCATTTGT
CCCTCACACCTACACAGTCACGGAAGAACTGACACTGAGGAGAAGCCGTATAAGTGTCAAGCATGTGGGCAAACTTTCCAACATCCTCGT
TACCTCTCCCACCACGTAAAGACTCACACAGCAGAGAAAACCTACAAATGCGAGCAGTGTCGGATGGCGTTTAATGGGTTCGCAAGCTTC
ACTAGACATGTGAGAACTCACACAAAAGACAGGCCATATAAATGTCAGGAATGTGGGAGAGCCTTCATTTATCCCTCGACATTTCAAAGA
CACATGACAACACACACTGGAGAGAAGCCCTATAAATGTCAGCACTGTGGGAAAGCCTTCACTTACCCCCAGGCTTTTCAAAGACATGAG
AAGACGCACACGGGAGAGAAGCCCTATGAATGCAAGCAGTGTGGGAAAACATTCAGTTGGTCTGAAACCTTGCGAGTCCACATGAGGATC
CACACTGGGGACAAACTCTATAAATGTGAACACTGTGGGAAGGCTTTTACCTCTTCCAGATCATTCCAAGGTCATTTGAGGACGCACACT
GGAGAGAAACCTTATGAGTGTAAACAATGTGGGAAAGCCTTCACTTGGTCCTCAACGTTTAGAGAACATGTGAGAATTCACACGCAAGAG
CAGCTCTATAAATGTGAACAATGTGGGAAGGCTTTTACCTCTTCCAGATCATTCCGAGGTCATTTGAGGACGCACACTGGAGAGAAGCCT
TATGAGTGTAAACAATGTGGAAAAACCTTCACTTGGTCCTCAACGTTTAGAGAACATGTGAGAATTCACACGCAAGAGCAGCTCCATAAA
TGTGAACACTGTGGGAAGGCCTTTACCTCTTCCAGAGCATTCCAAGGTCATTTGAGGATGCACACTGGAGAGAAGCCTTATGAGTGTAAA
CAATGTGGAAAAACCTTCACTTGGTCCTCAACCTTACATAATCATGTGAGGATGCACACTGGAGAGAAACCTCACAAATGTAAACAATGT
GGGATGTCCTTCAAGTGGCACTCCTCCTTCCGGAACCATCTGAGGATGCACACAGGACAGAAATCCCACGAATGTCAGTCATACTCAAAA
GCCTTCAGTTGCCAAGTCATTCTTTCTAAAACCAGTGAGAGCACACACTAAAGAGAAATTCTATAACTTTAATGGGGTAACCTCACATTA
ATTCATGTATAATGCTCCAGAAAATTCACACCAGGAGAGAAATCTTACAAGTATGATATTGTCTTTGTCAATACCTCATTTGTAAAACAG

>10245_10245_1_BRE-ZNF57_BRE_chr2_28248287_ENST00000342045_ZNF57_chr19_2915520_ENST00000306908_length(amino acids)=719AA_BP=165
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDA
EFLPDPSALQNLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWDSVVFEDVAVDFTLE
EWALLDSAQRDLYRDVMLETFRNLASVDDGTQFKANGSVSLQDMYGQEKSKEQTIPNFTGNNSCAYTLEKNCEGYGTEDHHKNLRNHMVD
RFCTHNEGNQYGEAIHQMPDLTLHKKVSAGEKPYECTKCRTVFTHLSSLKRHVKSHCGRKAPPGEECKQACICPSHLHSHGRTDTEEKPY
KCQACGQTFQHPRYLSHHVKTHTAEKTYKCEQCRMAFNGFASFTRHVRTHTKDRPYKCQECGRAFIYPSTFQRHMTTHTGEKPYKCQHCG
KAFTYPQAFQRHEKTHTGEKPYECKQCGKTFSWSETLRVHMRIHTGDKLYKCEHCGKAFTSSRSFQGHLRTHTGEKPYECKQCGKAFTWS
STFREHVRIHTQEQLYKCEQCGKAFTSSRSFRGHLRTHTGEKPYECKQCGKTFTWSSTFREHVRIHTQEQLHKCEHCGKAFTSSRAFQGH

--------------------------------------------------------------
>10245_10245_2_BRE-ZNF57_BRE_chr2_28248287_ENST00000344773_ZNF57_chr19_2915520_ENST00000306908_length(transcript)=2485nt_BP=633nt
GAGTGCGCACGCATCCTGCCCGCGGCGCGCGCGCAGGTCGGTGCGTCTGTCGGGGGCGCGCTCGGGTACCTGTACCCCACGTAGTCGCCG
GTTACCGATCGGACTAAGTTCCAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTC
TCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGC
ACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTGGGATATCATTTTCAAT
GCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTTGCAGAATCTTGCCTCC
TGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATGTAGCCGCCTCCGGGAG
AGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGCTGGGAAAAAAAACAAC
TGGGACTCAGTGGTCTTTGAGGATGTGGCTGTGGACTTCACCCTGGAGGAGTGGGCTTTGCTGGATTCTGCTCAGAGGGACCTCTACAGA
GATGTGATGCTGGAGACCTTCCGGAACCTGGCCTCAGTAGATGATGGGACTCAATTTAAAGCCAATGGGTCAGTTTCTCTGCAGGATATG
TACGGGCAAGAAAAATCTAAGGAACAGACAATACCAAACTTCACAGGAAATAATTCCTGTGCCTACACTTTAGAAAAAAATTGTGAAGGC
TATGGCACTGAAGACCACCACAAAAATCTGAGAAATCATATGGTGGACAGATTCTGTACACATAATGAAGGTAATCAATATGGAGAAGCC
ATCCATCAAATGCCAGATCTTACCCTGCACAAGAAAGTTTCTGCTGGAGAAAAACCATATGAATGCACCAAGTGCAGGACAGTCTTCACG
CATCTTTCTTCTCTTAAAAGGCACGTCAAGTCTCACTGTGGACGAAAAGCACCTCCAGGTGAGGAATGTAAGCAGGCCTGCATTTGTCCC
TCACACCTACACAGTCACGGAAGAACTGACACTGAGGAGAAGCCGTATAAGTGTCAAGCATGTGGGCAAACTTTCCAACATCCTCGTTAC
CTCTCCCACCACGTAAAGACTCACACAGCAGAGAAAACCTACAAATGCGAGCAGTGTCGGATGGCGTTTAATGGGTTCGCAAGCTTCACT
AGACATGTGAGAACTCACACAAAAGACAGGCCATATAAATGTCAGGAATGTGGGAGAGCCTTCATTTATCCCTCGACATTTCAAAGACAC
ATGACAACACACACTGGAGAGAAGCCCTATAAATGTCAGCACTGTGGGAAAGCCTTCACTTACCCCCAGGCTTTTCAAAGACATGAGAAG
ACGCACACGGGAGAGAAGCCCTATGAATGCAAGCAGTGTGGGAAAACATTCAGTTGGTCTGAAACCTTGCGAGTCCACATGAGGATCCAC
ACTGGGGACAAACTCTATAAATGTGAACACTGTGGGAAGGCTTTTACCTCTTCCAGATCATTCCAAGGTCATTTGAGGACGCACACTGGA
GAGAAACCTTATGAGTGTAAACAATGTGGGAAAGCCTTCACTTGGTCCTCAACGTTTAGAGAACATGTGAGAATTCACACGCAAGAGCAG
CTCTATAAATGTGAACAATGTGGGAAGGCTTTTACCTCTTCCAGATCATTCCGAGGTCATTTGAGGACGCACACTGGAGAGAAGCCTTAT
GAGTGTAAACAATGTGGAAAAACCTTCACTTGGTCCTCAACGTTTAGAGAACATGTGAGAATTCACACGCAAGAGCAGCTCCATAAATGT
GAACACTGTGGGAAGGCCTTTACCTCTTCCAGAGCATTCCAAGGTCATTTGAGGATGCACACTGGAGAGAAGCCTTATGAGTGTAAACAA
TGTGGAAAAACCTTCACTTGGTCCTCAACCTTACATAATCATGTGAGGATGCACACTGGAGAGAAACCTCACAAATGTAAACAATGTGGG
ATGTCCTTCAAGTGGCACTCCTCCTTCCGGAACCATCTGAGGATGCACACAGGACAGAAATCCCACGAATGTCAGTCATACTCAAAAGCC
TTCAGTTGCCAAGTCATTCTTTCTAAAACCAGTGAGAGCACACACTAAAGAGAAATTCTATAACTTTAATGGGGTAACCTCACATTAATT
CATGTATAATGCTCCAGAAAATTCACACCAGGAGAGAAATCTTACAAGTATGATATTGTCTTTGTCAATACCTCATTTGTAAAACAGACC

>10245_10245_2_BRE-ZNF57_BRE_chr2_28248287_ENST00000344773_ZNF57_chr19_2915520_ENST00000306908_length(amino acids)=719AA_BP=165
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDA
EFLPDPSALQNLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWDSVVFEDVAVDFTLE
EWALLDSAQRDLYRDVMLETFRNLASVDDGTQFKANGSVSLQDMYGQEKSKEQTIPNFTGNNSCAYTLEKNCEGYGTEDHHKNLRNHMVD
RFCTHNEGNQYGEAIHQMPDLTLHKKVSAGEKPYECTKCRTVFTHLSSLKRHVKSHCGRKAPPGEECKQACICPSHLHSHGRTDTEEKPY
KCQACGQTFQHPRYLSHHVKTHTAEKTYKCEQCRMAFNGFASFTRHVRTHTKDRPYKCQECGRAFIYPSTFQRHMTTHTGEKPYKCQHCG
KAFTYPQAFQRHEKTHTGEKPYECKQCGKTFSWSETLRVHMRIHTGDKLYKCEHCGKAFTSSRSFQGHLRTHTGEKPYECKQCGKAFTWS
STFREHVRIHTQEQLYKCEQCGKAFTSSRSFRGHLRTHTGEKPYECKQCGKTFTWSSTFREHVRIHTQEQLHKCEHCGKAFTSSRAFQGH

--------------------------------------------------------------
>10245_10245_3_BRE-ZNF57_BRE_chr2_28248287_ENST00000361704_ZNF57_chr19_2915520_ENST00000306908_length(transcript)=2421nt_BP=569nt
GGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTCCAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGG
CCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGA
GGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGA
CATTAAAGTGGGATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACC
CCTCAGCTTTGCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACC
AATTCCAATGTAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGG
AAATTTATGCTGGGAAAAAAAACAACTGGGACTCAGTGGTCTTTGAGGATGTGGCTGTGGACTTCACCCTGGAGGAGTGGGCTTTGCTGG
ATTCTGCTCAGAGGGACCTCTACAGAGATGTGATGCTGGAGACCTTCCGGAACCTGGCCTCAGTAGATGATGGGACTCAATTTAAAGCCA
ATGGGTCAGTTTCTCTGCAGGATATGTACGGGCAAGAAAAATCTAAGGAACAGACAATACCAAACTTCACAGGAAATAATTCCTGTGCCT
ACACTTTAGAAAAAAATTGTGAAGGCTATGGCACTGAAGACCACCACAAAAATCTGAGAAATCATATGGTGGACAGATTCTGTACACATA
ATGAAGGTAATCAATATGGAGAAGCCATCCATCAAATGCCAGATCTTACCCTGCACAAGAAAGTTTCTGCTGGAGAAAAACCATATGAAT
GCACCAAGTGCAGGACAGTCTTCACGCATCTTTCTTCTCTTAAAAGGCACGTCAAGTCTCACTGTGGACGAAAAGCACCTCCAGGTGAGG
AATGTAAGCAGGCCTGCATTTGTCCCTCACACCTACACAGTCACGGAAGAACTGACACTGAGGAGAAGCCGTATAAGTGTCAAGCATGTG
GGCAAACTTTCCAACATCCTCGTTACCTCTCCCACCACGTAAAGACTCACACAGCAGAGAAAACCTACAAATGCGAGCAGTGTCGGATGG
CGTTTAATGGGTTCGCAAGCTTCACTAGACATGTGAGAACTCACACAAAAGACAGGCCATATAAATGTCAGGAATGTGGGAGAGCCTTCA
TTTATCCCTCGACATTTCAAAGACACATGACAACACACACTGGAGAGAAGCCCTATAAATGTCAGCACTGTGGGAAAGCCTTCACTTACC
CCCAGGCTTTTCAAAGACATGAGAAGACGCACACGGGAGAGAAGCCCTATGAATGCAAGCAGTGTGGGAAAACATTCAGTTGGTCTGAAA
CCTTGCGAGTCCACATGAGGATCCACACTGGGGACAAACTCTATAAATGTGAACACTGTGGGAAGGCTTTTACCTCTTCCAGATCATTCC
AAGGTCATTTGAGGACGCACACTGGAGAGAAACCTTATGAGTGTAAACAATGTGGGAAAGCCTTCACTTGGTCCTCAACGTTTAGAGAAC
ATGTGAGAATTCACACGCAAGAGCAGCTCTATAAATGTGAACAATGTGGGAAGGCTTTTACCTCTTCCAGATCATTCCGAGGTCATTTGA
GGACGCACACTGGAGAGAAGCCTTATGAGTGTAAACAATGTGGAAAAACCTTCACTTGGTCCTCAACGTTTAGAGAACATGTGAGAATTC
ACACGCAAGAGCAGCTCCATAAATGTGAACACTGTGGGAAGGCCTTTACCTCTTCCAGAGCATTCCAAGGTCATTTGAGGATGCACACTG
GAGAGAAGCCTTATGAGTGTAAACAATGTGGAAAAACCTTCACTTGGTCCTCAACCTTACATAATCATGTGAGGATGCACACTGGAGAGA
AACCTCACAAATGTAAACAATGTGGGATGTCCTTCAAGTGGCACTCCTCCTTCCGGAACCATCTGAGGATGCACACAGGACAGAAATCCC
ACGAATGTCAGTCATACTCAAAAGCCTTCAGTTGCCAAGTCATTCTTTCTAAAACCAGTGAGAGCACACACTAAAGAGAAATTCTATAAC
TTTAATGGGGTAACCTCACATTAATTCATGTATAATGCTCCAGAAAATTCACACCAGGAGAGAAATCTTACAAGTATGATATTGTCTTTG

>10245_10245_3_BRE-ZNF57_BRE_chr2_28248287_ENST00000361704_ZNF57_chr19_2915520_ENST00000306908_length(amino acids)=719AA_BP=165
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDA
EFLPDPSALQNLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWDSVVFEDVAVDFTLE
EWALLDSAQRDLYRDVMLETFRNLASVDDGTQFKANGSVSLQDMYGQEKSKEQTIPNFTGNNSCAYTLEKNCEGYGTEDHHKNLRNHMVD
RFCTHNEGNQYGEAIHQMPDLTLHKKVSAGEKPYECTKCRTVFTHLSSLKRHVKSHCGRKAPPGEECKQACICPSHLHSHGRTDTEEKPY
KCQACGQTFQHPRYLSHHVKTHTAEKTYKCEQCRMAFNGFASFTRHVRTHTKDRPYKCQECGRAFIYPSTFQRHMTTHTGEKPYKCQHCG
KAFTYPQAFQRHEKTHTGEKPYECKQCGKTFSWSETLRVHMRIHTGDKLYKCEHCGKAFTSSRSFQGHLRTHTGEKPYECKQCGKAFTWS
STFREHVRIHTQEQLYKCEQCGKAFTSSRSFRGHLRTHTGEKPYECKQCGKTFTWSSTFREHVRIHTQEQLHKCEHCGKAFTSSRAFQGH

--------------------------------------------------------------
>10245_10245_4_BRE-ZNF57_BRE_chr2_28248287_ENST00000379624_ZNF57_chr19_2915520_ENST00000306908_length(transcript)=2464nt_BP=612nt
GCGGCGCGCGCGCAGGTCGGTGCGTCTGTCGGGGGCGCGCTCGGGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTC
CAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTG
GTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCC
AACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTGGGATATCATTTTCAATGCCCAATACCCAGAACTGCCT
CCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTTGCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAA
TGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATGTAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAA
TACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGCTGGGAAAAAAAACAACTGGGACTCAGTGGTCTTTGAG
GATGTGGCTGTGGACTTCACCCTGGAGGAGTGGGCTTTGCTGGATTCTGCTCAGAGGGACCTCTACAGAGATGTGATGCTGGAGACCTTC
CGGAACCTGGCCTCAGTAGATGATGGGACTCAATTTAAAGCCAATGGGTCAGTTTCTCTGCAGGATATGTACGGGCAAGAAAAATCTAAG
GAACAGACAATACCAAACTTCACAGGAAATAATTCCTGTGCCTACACTTTAGAAAAAAATTGTGAAGGCTATGGCACTGAAGACCACCAC
AAAAATCTGAGAAATCATATGGTGGACAGATTCTGTACACATAATGAAGGTAATCAATATGGAGAAGCCATCCATCAAATGCCAGATCTT
ACCCTGCACAAGAAAGTTTCTGCTGGAGAAAAACCATATGAATGCACCAAGTGCAGGACAGTCTTCACGCATCTTTCTTCTCTTAAAAGG
CACGTCAAGTCTCACTGTGGACGAAAAGCACCTCCAGGTGAGGAATGTAAGCAGGCCTGCATTTGTCCCTCACACCTACACAGTCACGGA
AGAACTGACACTGAGGAGAAGCCGTATAAGTGTCAAGCATGTGGGCAAACTTTCCAACATCCTCGTTACCTCTCCCACCACGTAAAGACT
CACACAGCAGAGAAAACCTACAAATGCGAGCAGTGTCGGATGGCGTTTAATGGGTTCGCAAGCTTCACTAGACATGTGAGAACTCACACA
AAAGACAGGCCATATAAATGTCAGGAATGTGGGAGAGCCTTCATTTATCCCTCGACATTTCAAAGACACATGACAACACACACTGGAGAG
AAGCCCTATAAATGTCAGCACTGTGGGAAAGCCTTCACTTACCCCCAGGCTTTTCAAAGACATGAGAAGACGCACACGGGAGAGAAGCCC
TATGAATGCAAGCAGTGTGGGAAAACATTCAGTTGGTCTGAAACCTTGCGAGTCCACATGAGGATCCACACTGGGGACAAACTCTATAAA
TGTGAACACTGTGGGAAGGCTTTTACCTCTTCCAGATCATTCCAAGGTCATTTGAGGACGCACACTGGAGAGAAACCTTATGAGTGTAAA
CAATGTGGGAAAGCCTTCACTTGGTCCTCAACGTTTAGAGAACATGTGAGAATTCACACGCAAGAGCAGCTCTATAAATGTGAACAATGT
GGGAAGGCTTTTACCTCTTCCAGATCATTCCGAGGTCATTTGAGGACGCACACTGGAGAGAAGCCTTATGAGTGTAAACAATGTGGAAAA
ACCTTCACTTGGTCCTCAACGTTTAGAGAACATGTGAGAATTCACACGCAAGAGCAGCTCCATAAATGTGAACACTGTGGGAAGGCCTTT
ACCTCTTCCAGAGCATTCCAAGGTCATTTGAGGATGCACACTGGAGAGAAGCCTTATGAGTGTAAACAATGTGGAAAAACCTTCACTTGG
TCCTCAACCTTACATAATCATGTGAGGATGCACACTGGAGAGAAACCTCACAAATGTAAACAATGTGGGATGTCCTTCAAGTGGCACTCC
TCCTTCCGGAACCATCTGAGGATGCACACAGGACAGAAATCCCACGAATGTCAGTCATACTCAAAAGCCTTCAGTTGCCAAGTCATTCTT
TCTAAAACCAGTGAGAGCACACACTAAAGAGAAATTCTATAACTTTAATGGGGTAACCTCACATTAATTCATGTATAATGCTCCAGAAAA
TTCACACCAGGAGAGAAATCTTACAAGTATGATATTGTCTTTGTCAATACCTCATTTGTAAAACAGACCCATTAGTCGTGAATTTCCAGC

>10245_10245_4_BRE-ZNF57_BRE_chr2_28248287_ENST00000379624_ZNF57_chr19_2915520_ENST00000306908_length(amino acids)=719AA_BP=165
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDA
EFLPDPSALQNLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWDSVVFEDVAVDFTLE
EWALLDSAQRDLYRDVMLETFRNLASVDDGTQFKANGSVSLQDMYGQEKSKEQTIPNFTGNNSCAYTLEKNCEGYGTEDHHKNLRNHMVD
RFCTHNEGNQYGEAIHQMPDLTLHKKVSAGEKPYECTKCRTVFTHLSSLKRHVKSHCGRKAPPGEECKQACICPSHLHSHGRTDTEEKPY
KCQACGQTFQHPRYLSHHVKTHTAEKTYKCEQCRMAFNGFASFTRHVRTHTKDRPYKCQECGRAFIYPSTFQRHMTTHTGEKPYKCQHCG
KAFTYPQAFQRHEKTHTGEKPYECKQCGKTFSWSETLRVHMRIHTGDKLYKCEHCGKAFTSSRSFQGHLRTHTGEKPYECKQCGKAFTWS
STFREHVRIHTQEQLYKCEQCGKAFTSSRSFRGHLRTHTGEKPYECKQCGKTFTWSSTFREHVRIHTQEQLHKCEHCGKAFTSSRAFQGH

--------------------------------------------------------------
>10245_10245_5_BRE-ZNF57_BRE_chr2_28248287_ENST00000379632_ZNF57_chr19_2915520_ENST00000306908_length(transcript)=2487nt_BP=635nt
GGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTCCAGAAGCAAGAGATAAAGTAATAATGGGTACTGTGGGGAAAAA
CACAGAAGAACAATTCGGTAATATAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGC
TCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCT
GCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTGGGATATCATTTTCA
ATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTTGCAGAATCTTGCCT
CCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATGTAGCCGCCTCCGGG
AGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGCTGGGAAAAAAAACA
ACTGGGACTCAGTGGTCTTTGAGGATGTGGCTGTGGACTTCACCCTGGAGGAGTGGGCTTTGCTGGATTCTGCTCAGAGGGACCTCTACA
GAGATGTGATGCTGGAGACCTTCCGGAACCTGGCCTCAGTAGATGATGGGACTCAATTTAAAGCCAATGGGTCAGTTTCTCTGCAGGATA
TGTACGGGCAAGAAAAATCTAAGGAACAGACAATACCAAACTTCACAGGAAATAATTCCTGTGCCTACACTTTAGAAAAAAATTGTGAAG
GCTATGGCACTGAAGACCACCACAAAAATCTGAGAAATCATATGGTGGACAGATTCTGTACACATAATGAAGGTAATCAATATGGAGAAG
CCATCCATCAAATGCCAGATCTTACCCTGCACAAGAAAGTTTCTGCTGGAGAAAAACCATATGAATGCACCAAGTGCAGGACAGTCTTCA
CGCATCTTTCTTCTCTTAAAAGGCACGTCAAGTCTCACTGTGGACGAAAAGCACCTCCAGGTGAGGAATGTAAGCAGGCCTGCATTTGTC
CCTCACACCTACACAGTCACGGAAGAACTGACACTGAGGAGAAGCCGTATAAGTGTCAAGCATGTGGGCAAACTTTCCAACATCCTCGTT
ACCTCTCCCACCACGTAAAGACTCACACAGCAGAGAAAACCTACAAATGCGAGCAGTGTCGGATGGCGTTTAATGGGTTCGCAAGCTTCA
CTAGACATGTGAGAACTCACACAAAAGACAGGCCATATAAATGTCAGGAATGTGGGAGAGCCTTCATTTATCCCTCGACATTTCAAAGAC
ACATGACAACACACACTGGAGAGAAGCCCTATAAATGTCAGCACTGTGGGAAAGCCTTCACTTACCCCCAGGCTTTTCAAAGACATGAGA
AGACGCACACGGGAGAGAAGCCCTATGAATGCAAGCAGTGTGGGAAAACATTCAGTTGGTCTGAAACCTTGCGAGTCCACATGAGGATCC
ACACTGGGGACAAACTCTATAAATGTGAACACTGTGGGAAGGCTTTTACCTCTTCCAGATCATTCCAAGGTCATTTGAGGACGCACACTG
GAGAGAAACCTTATGAGTGTAAACAATGTGGGAAAGCCTTCACTTGGTCCTCAACGTTTAGAGAACATGTGAGAATTCACACGCAAGAGC
AGCTCTATAAATGTGAACAATGTGGGAAGGCTTTTACCTCTTCCAGATCATTCCGAGGTCATTTGAGGACGCACACTGGAGAGAAGCCTT
ATGAGTGTAAACAATGTGGAAAAACCTTCACTTGGTCCTCAACGTTTAGAGAACATGTGAGAATTCACACGCAAGAGCAGCTCCATAAAT
GTGAACACTGTGGGAAGGCCTTTACCTCTTCCAGAGCATTCCAAGGTCATTTGAGGATGCACACTGGAGAGAAGCCTTATGAGTGTAAAC
AATGTGGAAAAACCTTCACTTGGTCCTCAACCTTACATAATCATGTGAGGATGCACACTGGAGAGAAACCTCACAAATGTAAACAATGTG
GGATGTCCTTCAAGTGGCACTCCTCCTTCCGGAACCATCTGAGGATGCACACAGGACAGAAATCCCACGAATGTCAGTCATACTCAAAAG
CCTTCAGTTGCCAAGTCATTCTTTCTAAAACCAGTGAGAGCACACACTAAAGAGAAATTCTATAACTTTAATGGGGTAACCTCACATTAA
TTCATGTATAATGCTCCAGAAAATTCACACCAGGAGAGAAATCTTACAAGTATGATATTGTCTTTGTCAATACCTCATTTGTAAAACAGA

>10245_10245_5_BRE-ZNF57_BRE_chr2_28248287_ENST00000379632_ZNF57_chr19_2915520_ENST00000306908_length(amino acids)=719AA_BP=165
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDA
EFLPDPSALQNLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWDSVVFEDVAVDFTLE
EWALLDSAQRDLYRDVMLETFRNLASVDDGTQFKANGSVSLQDMYGQEKSKEQTIPNFTGNNSCAYTLEKNCEGYGTEDHHKNLRNHMVD
RFCTHNEGNQYGEAIHQMPDLTLHKKVSAGEKPYECTKCRTVFTHLSSLKRHVKSHCGRKAPPGEECKQACICPSHLHSHGRTDTEEKPY
KCQACGQTFQHPRYLSHHVKTHTAEKTYKCEQCRMAFNGFASFTRHVRTHTKDRPYKCQECGRAFIYPSTFQRHMTTHTGEKPYKCQHCG
KAFTYPQAFQRHEKTHTGEKPYECKQCGKTFSWSETLRVHMRIHTGDKLYKCEHCGKAFTSSRSFQGHLRTHTGEKPYECKQCGKAFTWS
STFREHVRIHTQEQLYKCEQCGKAFTSSRSFRGHLRTHTGEKPYECKQCGKTFTWSSTFREHVRIHTQEQLHKCEHCGKAFTSSRAFQGH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for BRE-ZNF57


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BRE-ZNF57


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BRE-ZNF57


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource