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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF589-FBXW12 (FusionGDB2 ID:102490)

Fusion Gene Summary for ZNF589-FBXW12

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF589-FBXW12
Fusion gene ID: 102490
HgeneTgene
Gene symbol

ZNF589

FBXW12

Gene ID

51385

285231

Gene namezinc finger protein 589F-box and WD repeat domain containing 12
SynonymsSZF1FBW12|FBXO12|FBXO35
Cytomap

3p21.31

3p21.31

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 589KRAB-zinc finger protein SZF1-1stem cell zinc finger protein 1F-box/WD repeat-containing protein 12F-box and WD-40 domain protein 12F-box and WD-40 domain-containing protein 12F-box only protein 35F-box- and WD40-repeat-containing protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000454212, ENST00000354698, 
ENST00000412564, ENST00000427617, 
ENST00000440261, 		ENST00000296438, 
ENST00000415155, ENST00000445170, 
ENST00000436231, ENST00000468158, 
Fusion gene scores* DoF score6 X 5 X 6=1805 X 5 X 5=125
# samples 88
** MAII scorelog2(8/180*10)=-1.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/125*10)=-0.643856189774725
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF589 [Title/Abstract] AND FBXW12 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF589(48302429)-FBXW12(48414797), # samples:1
ZNF589(48302429)-FBXW12(48416844), # samples:1
ZNF589(48302429)-FBXW12(48415038), # samples:1
Anticipated loss of major functional domain due to fusion event.ZNF589-FBXW12 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneZNF589

GO:0000122

negative regulation of transcription by RNA polymerase II

12097288


check buttonFusion gene breakpoints across ZNF589 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FBXW12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-12-1597-01BZNF589chr3

48302429

+FBXW12chr3

48415038

+
ChimerDB4GBMTCGA-12-3652-01AZNF589chr3

48302429

+FBXW12chr3

48416844

+
ChimerDB4STADTCGA-D7-A4YVZNF589chr3

48302429

+FBXW12chr3

48414797

+


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Fusion Gene ORF analysis for ZNF589-FBXW12

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000454212ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48415038

+
3UTR-3CDSENST00000454212ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48416844

+
3UTR-3CDSENST00000454212ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48414797

+
3UTR-3CDSENST00000454212ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48415038

+
3UTR-3CDSENST00000454212ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48416844

+
3UTR-3CDSENST00000454212ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48414797

+
3UTR-3CDSENST00000454212ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48415038

+
3UTR-3CDSENST00000454212ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48416844

+
3UTR-3CDSENST00000454212ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48414797

+
3UTR-5UTRENST00000454212ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48416844

+
3UTR-intronENST00000454212ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48415038

+
3UTR-intronENST00000454212ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48414797

+
3UTR-intronENST00000454212ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48415038

+
3UTR-intronENST00000454212ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48416844

+
3UTR-intronENST00000454212ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48414797

+
5CDS-5UTRENST00000354698ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48416844

+
5CDS-5UTRENST00000412564ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48416844

+
5CDS-5UTRENST00000427617ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48416844

+
5CDS-5UTRENST00000440261ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48416844

+
5CDS-intronENST00000354698ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48415038

+
5CDS-intronENST00000354698ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48414797

+
5CDS-intronENST00000354698ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48415038

+
5CDS-intronENST00000354698ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48416844

+
5CDS-intronENST00000354698ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48414797

+
5CDS-intronENST00000412564ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48415038

+
5CDS-intronENST00000412564ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48414797

+
5CDS-intronENST00000412564ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48415038

+
5CDS-intronENST00000412564ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48416844

+
5CDS-intronENST00000412564ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48414797

+
5CDS-intronENST00000427617ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48415038

+
5CDS-intronENST00000427617ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48414797

+
5CDS-intronENST00000427617ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48415038

+
5CDS-intronENST00000427617ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48416844

+
5CDS-intronENST00000427617ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48414797

+
5CDS-intronENST00000440261ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48415038

+
5CDS-intronENST00000440261ENST00000436231ZNF589chr3

48302429

+FBXW12chr3

48414797

+
5CDS-intronENST00000440261ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48415038

+
5CDS-intronENST00000440261ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48416844

+
5CDS-intronENST00000440261ENST00000468158ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000354698ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000354698ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000354698ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000354698ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000354698ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000354698ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000412564ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000412564ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000412564ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000412564ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000412564ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000412564ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000427617ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000427617ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000427617ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000427617ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000427617ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000427617ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000440261ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000440261ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000440261ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000440261ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48414797

+
Frame-shiftENST00000440261ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48415038

+
Frame-shiftENST00000440261ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48414797

+
In-frameENST00000354698ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48416844

+
In-frameENST00000354698ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48416844

+
In-frameENST00000354698ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48416844

+
In-frameENST00000412564ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48416844

+
In-frameENST00000412564ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48416844

+
In-frameENST00000412564ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48416844

+
In-frameENST00000427617ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48416844

+
In-frameENST00000427617ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48416844

+
In-frameENST00000427617ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48416844

+
In-frameENST00000440261ENST00000296438ZNF589chr3

48302429

+FBXW12chr3

48416844

+
In-frameENST00000440261ENST00000415155ZNF589chr3

48302429

+FBXW12chr3

48416844

+
In-frameENST00000440261ENST00000445170ZNF589chr3

48302429

+FBXW12chr3

48416844

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000354698ZNF589chr348302429+ENST00000296438FBXW12chr348416844+1470295331403456
ENST00000354698ZNF589chr348302429+ENST00000415155FBXW12chr348416844+1222295331193386
ENST00000354698ZNF589chr348302429+ENST00000445170FBXW12chr348416844+1432295331403456
ENST00000427617ZNF589chr348302429+ENST00000296438FBXW12chr348416844+1470295331403456
ENST00000427617ZNF589chr348302429+ENST00000415155FBXW12chr348416844+1222295331193386
ENST00000427617ZNF589chr348302429+ENST00000445170FBXW12chr348416844+1432295331403456
ENST00000412564ZNF589chr348302429+ENST00000296438FBXW12chr348416844+1469294321402456
ENST00000412564ZNF589chr348302429+ENST00000415155FBXW12chr348416844+1221294321192386
ENST00000412564ZNF589chr348302429+ENST00000445170FBXW12chr348416844+1431294321402456
ENST00000440261ZNF589chr348302429+ENST00000296438FBXW12chr348416844+1464289271397456
ENST00000440261ZNF589chr348302429+ENST00000415155FBXW12chr348416844+1216289271187386
ENST00000440261ZNF589chr348302429+ENST00000445170FBXW12chr348416844+1426289271397456

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000354698ENST00000296438ZNF589chr348302429+FBXW12chr348416844+0.0047716070.9952284
ENST00000354698ENST00000415155ZNF589chr348302429+FBXW12chr348416844+0.0131327370.9868673
ENST00000354698ENST00000445170ZNF589chr348302429+FBXW12chr348416844+0.0047052340.99529475
ENST00000427617ENST00000296438ZNF589chr348302429+FBXW12chr348416844+0.0047716070.9952284
ENST00000427617ENST00000415155ZNF589chr348302429+FBXW12chr348416844+0.0131327370.9868673
ENST00000427617ENST00000445170ZNF589chr348302429+FBXW12chr348416844+0.0047052340.99529475
ENST00000412564ENST00000296438ZNF589chr348302429+FBXW12chr348416844+0.0047853180.9952147
ENST00000412564ENST00000415155ZNF589chr348302429+FBXW12chr348416844+0.013119530.9868804
ENST00000412564ENST00000445170ZNF589chr348302429+FBXW12chr348416844+0.0047040970.99529594
ENST00000440261ENST00000296438ZNF589chr348302429+FBXW12chr348416844+0.0048629270.99513704
ENST00000440261ENST00000415155ZNF589chr348302429+FBXW12chr348416844+0.013132130.9868679
ENST00000440261ENST00000445170ZNF589chr348302429+FBXW12chr348416844+0.0048441720.9951558

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Fusion Genomic Features for ZNF589-FBXW12


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNF589chr348302429+FBXW12chr348415037+4.95E-050.9999505
ZNF589chr348302429+FBXW12chr348414797+5.29E-060.99999475
ZNF589chr348302429+FBXW12chr348416843+2.15E-070.99999976
ZNF589chr348302429+FBXW12chr348415037+4.95E-050.9999505
ZNF589chr348302429+FBXW12chr348414797+5.29E-060.99999475
ZNF589chr348302429+FBXW12chr348416843+2.15E-070.99999976

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZNF589-FBXW12


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:48302429/chr3:48414797)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFBXW12chr3:48302429chr3:48416844ENST00000296438311136_17495465.0RepeatNote=WD 2
TgeneFBXW12chr3:48302429chr3:48416844ENST00000296438311178_21795465.0RepeatNote=WD 3
TgeneFBXW12chr3:48302429chr3:48416844ENST00000296438311222_26395465.0RepeatNote=WD 4
TgeneFBXW12chr3:48302429chr3:48416844ENST00000296438311270_31595465.0RepeatNote=WD 5
TgeneFBXW12chr3:48302429chr3:48416844ENST00000296438311320_36795465.0RepeatNote=WD 6
TgeneFBXW12chr3:48302429chr3:48416844ENST00000296438311370_40795465.0RepeatNote=WD 7
TgeneFBXW12chr3:48302429chr3:48416844ENST00000296438311416_46195465.0RepeatNote=WD 8
TgeneFBXW12chr3:48302429chr3:48416844ENST00000415155310136_17495395.0RepeatNote=WD 2
TgeneFBXW12chr3:48302429chr3:48416844ENST00000415155310178_21795395.0RepeatNote=WD 3
TgeneFBXW12chr3:48302429chr3:48416844ENST00000415155310222_26395395.0RepeatNote=WD 4
TgeneFBXW12chr3:48302429chr3:48416844ENST00000415155310270_31595395.0RepeatNote=WD 5
TgeneFBXW12chr3:48302429chr3:48416844ENST00000415155310320_36795395.0RepeatNote=WD 6
TgeneFBXW12chr3:48302429chr3:48416844ENST00000415155310370_40795395.0RepeatNote=WD 7
TgeneFBXW12chr3:48302429chr3:48416844ENST00000415155310416_46195395.0RepeatNote=WD 8
TgeneFBXW12chr3:48302429chr3:48416844ENST00000445170210136_17476446.0RepeatNote=WD 2
TgeneFBXW12chr3:48302429chr3:48416844ENST00000445170210178_21776446.0RepeatNote=WD 3
TgeneFBXW12chr3:48302429chr3:48416844ENST00000445170210222_26376446.0RepeatNote=WD 4
TgeneFBXW12chr3:48302429chr3:48416844ENST00000445170210270_31576446.0RepeatNote=WD 5
TgeneFBXW12chr3:48302429chr3:48416844ENST00000445170210320_36776446.0RepeatNote=WD 6
TgeneFBXW12chr3:48302429chr3:48416844ENST00000445170210370_40776446.0RepeatNote=WD 7
TgeneFBXW12chr3:48302429chr3:48416844ENST00000445170210416_46176446.0RepeatNote=WD 8
TgeneFBXW12chr3:48302429chr3:48416844ENST0000044517021089_13276446.0RepeatNote=WD 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF589chr3:48302429chr3:48416844ENST00000354698+3435_10874365.0DomainKRAB
HgeneZNF589chr3:48302429chr3:48416844ENST00000354698+34248_27074365.0Zinc fingerC2H2-type 1
HgeneZNF589chr3:48302429chr3:48416844ENST00000354698+34276_29874365.0Zinc fingerC2H2-type 2
HgeneZNF589chr3:48302429chr3:48416844ENST00000354698+34304_32674365.0Zinc fingerC2H2-type 3
HgeneZNF589chr3:48302429chr3:48416844ENST00000354698+34332_35474365.0Zinc fingerC2H2-type 4
TgeneFBXW12chr3:48302429chr3:48416844ENST000002964383111_4595465.0DomainF-box
TgeneFBXW12chr3:48302429chr3:48416844ENST000004151553101_4595395.0DomainF-box
TgeneFBXW12chr3:48302429chr3:48416844ENST000004451702101_4576446.0DomainF-box
TgeneFBXW12chr3:48302429chr3:48416844ENST0000029643831189_13295465.0RepeatNote=WD 1
TgeneFBXW12chr3:48302429chr3:48416844ENST0000041515531089_13295395.0RepeatNote=WD 1


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Fusion Gene Sequence for ZNF589-FBXW12


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102490_102490_1_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000354698_FBXW12_chr3_48416844_ENST00000296438_length(transcript)=1470nt_BP=295nt
CGGTGCGCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAG
CAGCTACTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACT
TTCGAGGATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAA
AATCTCAGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCA
ATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTC
CATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGAC
AGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGC
GATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTA
CACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGA
CCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATA
ACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATC
CAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTT
ACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGG
GTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGC
TGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGG
GTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAATATGGAAACTAACAAAATTGACCTTGCATCATCTTC

>102490_102490_1_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000354698_FBXW12_chr3_48416844_ENST00000296438_length(amino acids)=456AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQ
PCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTF
LPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSI
TGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILV

--------------------------------------------------------------
>102490_102490_2_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000354698_FBXW12_chr3_48416844_ENST00000415155_length(transcript)=1222nt_BP=295nt
CGGTGCGCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAG
CAGCTACTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACT
TTCGAGGATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAA
AATCTCAGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCA
ATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACA
CTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTT
GCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACC
TTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAA
AAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTG
GCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGC
ATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCC
GAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGAT
CACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTG

>102490_102490_2_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000354698_FBXW12_chr3_48416844_ENST00000415155_length(amino acids)=386AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQ
VFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMG
ASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVM

--------------------------------------------------------------
>102490_102490_3_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000354698_FBXW12_chr3_48416844_ENST00000445170_length(transcript)=1432nt_BP=295nt
CGGTGCGCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAG
CAGCTACTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACT
TTCGAGGATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAA
AATCTCAGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCA
ATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTC
CATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGAC
AGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGC
GATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTA
CACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGA
CCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATA
ACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATC
CAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTT
ACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGG
GTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGC
TGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGG

>102490_102490_3_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000354698_FBXW12_chr3_48416844_ENST00000445170_length(amino acids)=456AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQ
PCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTF
LPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSI
TGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILV

--------------------------------------------------------------
>102490_102490_4_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000412564_FBXW12_chr3_48416844_ENST00000296438_length(transcript)=1469nt_BP=294nt
GGTGCGCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAGC
AGCTACTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACTT
TCGAGGATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAAA
ATCTCAGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAA
TCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCC
ATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACA
GGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCG
ATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTAC
ACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGAC
CATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAA
CACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCC
AAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTA
CCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGG
TGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCT
GCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGG
TGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAATATGGAAACTAACAAAATTGACCTTGCATCATCTTCT

>102490_102490_4_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000412564_FBXW12_chr3_48416844_ENST00000296438_length(amino acids)=456AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQ
PCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTF
LPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSI
TGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILV

--------------------------------------------------------------
>102490_102490_5_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000412564_FBXW12_chr3_48416844_ENST00000415155_length(transcript)=1221nt_BP=294nt
GGTGCGCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAGC
AGCTACTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACTT
TCGAGGATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAAA
ATCTCAGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAA
TCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACAC
TGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTG
CATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCT
TTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAA
AGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGG
CAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCA
TCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCG
AGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATC
ACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGG

>102490_102490_5_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000412564_FBXW12_chr3_48416844_ENST00000415155_length(amino acids)=386AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQ
VFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMG
ASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVM

--------------------------------------------------------------
>102490_102490_6_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000412564_FBXW12_chr3_48416844_ENST00000445170_length(transcript)=1431nt_BP=294nt
GGTGCGCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAGC
AGCTACTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACTT
TCGAGGATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAAA
ATCTCAGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAA
TCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCC
ATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACA
GGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCG
ATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTAC
ACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGAC
CATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAA
CACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCC
AAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTA
CCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGG
TGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCT
GCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGG

>102490_102490_6_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000412564_FBXW12_chr3_48416844_ENST00000445170_length(amino acids)=456AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQ
PCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTF
LPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSI
TGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILV

--------------------------------------------------------------
>102490_102490_7_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000427617_FBXW12_chr3_48416844_ENST00000296438_length(transcript)=1470nt_BP=295nt
CGGTGCGCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAG
CAGCTACTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACT
TTCGAGGATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAA
AATCTCAGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCA
ATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTC
CATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGAC
AGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGC
GATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTA
CACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGA
CCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATA
ACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATC
CAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTT
ACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGG
GTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGC
TGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGG
GTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAATATGGAAACTAACAAAATTGACCTTGCATCATCTTC

>102490_102490_7_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000427617_FBXW12_chr3_48416844_ENST00000296438_length(amino acids)=456AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQ
PCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTF
LPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSI
TGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILV

--------------------------------------------------------------
>102490_102490_8_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000427617_FBXW12_chr3_48416844_ENST00000415155_length(transcript)=1222nt_BP=295nt
CGGTGCGCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAG
CAGCTACTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACT
TTCGAGGATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAA
AATCTCAGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCA
ATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACA
CTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTT
GCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACC
TTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAA
AAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTG
GCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGC
ATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCC
GAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGAT
CACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTG

>102490_102490_8_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000427617_FBXW12_chr3_48416844_ENST00000415155_length(amino acids)=386AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQ
VFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMG
ASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVM

--------------------------------------------------------------
>102490_102490_9_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000427617_FBXW12_chr3_48416844_ENST00000445170_length(transcript)=1432nt_BP=295nt
CGGTGCGCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAG
CAGCTACTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACT
TTCGAGGATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAA
AATCTCAGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCA
ATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTC
CATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGAC
AGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGC
GATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTA
CACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGA
CCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATA
ACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATC
CAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTT
ACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGG
GTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGC
TGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGG

>102490_102490_9_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000427617_FBXW12_chr3_48416844_ENST00000445170_length(amino acids)=456AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQ
PCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTF
LPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSI
TGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILV

--------------------------------------------------------------
>102490_102490_10_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000440261_FBXW12_chr3_48416844_ENST00000296438_length(transcript)=1464nt_BP=289nt
GCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAGCAGCTA
CTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACTTTCGAG
GATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAAAATCTC
AGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATT
TGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTC
TCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGAC
GCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCT
GCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGC
TCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCA
GAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTG
ATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCA
TATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGT
GGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGAT
CCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGT
CACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGG
AAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAATATGGAAACTAACAAAATTGACCTTGCATCATCTTCTGCAAT

>102490_102490_10_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000440261_FBXW12_chr3_48416844_ENST00000296438_length(amino acids)=456AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQ
PCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTF
LPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSI
TGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILV

--------------------------------------------------------------
>102490_102490_11_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000440261_FBXW12_chr3_48416844_ENST00000415155_length(transcript)=1216nt_BP=289nt
GCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAGCAGCTA
CTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACTTTCGAG
GATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAAAATCTC
AGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATT
TGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCT
GGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGT
GGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTC
CCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACA
GAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCT
CATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACT
GGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAAC
TCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACA
ACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATG

>102490_102490_11_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000440261_FBXW12_chr3_48416844_ENST00000415155_length(amino acids)=386AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQ
VFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMG
ASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVM

--------------------------------------------------------------
>102490_102490_12_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000440261_FBXW12_chr3_48416844_ENST00000445170_length(transcript)=1426nt_BP=289nt
GCATTCTAATCCGTTTCACACACGGTGCTGCTACCTCGTTTGCTTCGTGCGTGCGTGCGCGCGCAGATGTGGGCCCCGCGGGAGCAGCTA
CTGGGCTGGACTGCGGAAGCTCTGCCTGCCAAGGATTCTGCCTGGCCCTGGGAAGAGAAGCCTAGATATCTGGGACCAGTGACTTTCGAG
GATGTGGCTGTGCTTTTCACTGAGGCAGAGTGGAAGAGACTGAGCCTTGAGCAGAGGAACCTATACAAAGAAGTGATGCTGGAAAATCTC
AGGAATCTGGTCTCATTGGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATT
TGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTC
TCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGAC
GCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCT
GCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGC
TCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCA
GAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTG
ATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCA
TATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGT
GGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGAT
CCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGT
CACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGG

>102490_102490_12_ZNF589-FBXW12_ZNF589_chr3_48302429_ENST00000440261_FBXW12_chr3_48416844_ENST00000445170_length(amino acids)=456AA_BP=1
MLPRLLRACVRAQMWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAFE
TELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQ
PCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTF
LPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSI
TGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNF589-FBXW12


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF589-FBXW12


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF589-FBXW12


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource