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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF592-UBE2L3 (FusionGDB2 ID:102496)

Fusion Gene Summary for ZNF592-UBE2L3

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF592-UBE2L3
Fusion gene ID: 102496
HgeneTgene
Gene symbol

ZNF592

UBE2L3

Gene ID

9640

7332

Gene namezinc finger protein 592ubiquitin conjugating enzyme E2 L3
SynonymsCAMOS|SCAR5E2-F1|L-UBC|UBCH7|UbcM4
Cytomap

15q25.3

22q11.21

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 592ubiquitin-conjugating enzyme E2 L3E2 ubiquitin-conjugating enzyme L3ubiquitin carrier protein L3ubiquitin conjugating enzyme E2L 3ubiquitin-conjugating enzyme E2-F1ubiquitin-conjugating enzyme UBCH7ubiquitin-protein ligase L3
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000299927, ENST00000560079, 
ENST00000342192, ENST00000458578, 
ENST00000545681, 
Fusion gene scores* DoF score5 X 5 X 3=7520 X 14 X 7=1960
# samples 522
** MAII scorelog2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(22/1960*10)=-3.15527822547791
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF592 [Title/Abstract] AND UBE2L3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF592(85343208)-UBE2L3(21965145), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneUBE2L3

GO:0000209

protein polyubiquitination

10888878|14765125

TgeneUBE2L3

GO:0006355

regulation of transcription, DNA-templated

17003263

TgeneUBE2L3

GO:0016567

protein ubiquitination

9990509|21532592

TgeneUBE2L3

GO:0070979

protein K11-linked ubiquitination

20061386

TgeneUBE2L3

GO:0071385

cellular response to glucocorticoid stimulus

17003263


check buttonFusion gene breakpoints across ZNF592 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across UBE2L3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-8525ZNF592chr15

85343208

+UBE2L3chr22

21965145

+


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Fusion Gene ORF analysis for ZNF592-UBE2L3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000299927ENST00000342192ZNF592chr15

85343208

+UBE2L3chr22

21965145

+
In-frameENST00000299927ENST00000458578ZNF592chr15

85343208

+UBE2L3chr22

21965145

+
In-frameENST00000299927ENST00000545681ZNF592chr15

85343208

+UBE2L3chr22

21965145

+
In-frameENST00000560079ENST00000342192ZNF592chr15

85343208

+UBE2L3chr22

21965145

+
In-frameENST00000560079ENST00000458578ZNF592chr15

85343208

+UBE2L3chr22

21965145

+
In-frameENST00000560079ENST00000545681ZNF592chr15

85343208

+UBE2L3chr22

21965145

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000560079ZNF592chr1585343208+ENST00000458578UBE2L3chr2221965145+4486356124939021217
ENST00000560079ZNF592chr1585343208+ENST00000342192UBE2L3chr2221965145+6268356124939021217
ENST00000560079ZNF592chr1585343208+ENST00000545681UBE2L3chr2221965145+4583356124939021217
ENST00000299927ZNF592chr1585343208+ENST00000458578UBE2L3chr2221965145+422032952236361204
ENST00000299927ZNF592chr1585343208+ENST00000342192UBE2L3chr2221965145+600232952236361204
ENST00000299927ZNF592chr1585343208+ENST00000545681UBE2L3chr2221965145+431732952236361204

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000560079ENST00000458578ZNF592chr1585343208+UBE2L3chr2221965145+0.0015069810.99849296
ENST00000560079ENST00000342192ZNF592chr1585343208+UBE2L3chr2221965145+0.0011106030.9988894
ENST00000560079ENST00000545681ZNF592chr1585343208+UBE2L3chr2221965145+0.0013771070.9986229
ENST00000299927ENST00000458578ZNF592chr1585343208+UBE2L3chr2221965145+0.001206490.9987935
ENST00000299927ENST00000342192ZNF592chr1585343208+UBE2L3chr2221965145+0.0008642550.9991358
ENST00000299927ENST00000545681ZNF592chr1585343208+UBE2L3chr2221965145+0.0011015040.9988985

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Fusion Genomic Features for ZNF592-UBE2L3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNF592chr1585343208+UBE2L3chr2221965145+2.23E-050.9999777
ZNF592chr1585343208+UBE2L3chr2221965145+2.23E-050.9999777

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZNF592-UBE2L3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:85343208/chr22:21965145)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+781013_103610911268.0Zinc fingerC2H2-type 10
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+781043_106910911268.0Zinc fingerC2H2-type 11%3B atypical
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+78587_61210911268.0Zinc fingerC2H2-type 1%3B atypical
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+78615_63910911268.0Zinc fingerC2H2-type 2%3B atypical
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+78711_73110911268.0Zinc fingerC2H2-type 3%3B degenerate
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+78740_76410911268.0Zinc fingerC2H2-type 4
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+78768_79010911268.0Zinc fingerC2H2-type 5%3B atypical
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+78799_82210911268.0Zinc fingerC2H2-type 6
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+78827_85010911268.0Zinc fingerC2H2-type 7
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+78892_91510911268.0Zinc fingerC2H2-type 8
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+78983_100610911268.0Zinc fingerC2H2-type 9
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+10111013_103610911268.0Zinc fingerC2H2-type 10
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+10111043_106910911268.0Zinc fingerC2H2-type 11%3B atypical
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+1011587_61210911268.0Zinc fingerC2H2-type 1%3B atypical
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+1011615_63910911268.0Zinc fingerC2H2-type 2%3B atypical
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+1011711_73110911268.0Zinc fingerC2H2-type 3%3B degenerate
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+1011740_76410911268.0Zinc fingerC2H2-type 4
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+1011768_79010911268.0Zinc fingerC2H2-type 5%3B atypical
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+1011799_82210911268.0Zinc fingerC2H2-type 6
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+1011827_85010911268.0Zinc fingerC2H2-type 7
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+1011892_91510911268.0Zinc fingerC2H2-type 8
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+1011983_100610911268.0Zinc fingerC2H2-type 9

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+781124_114610911268.0Zinc fingerC2H2-type 12%3B atypical
HgeneZNF592chr15:85343208chr22:21965145ENST00000299927+781153_117610911268.0Zinc fingerC2H2-type 13
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+10111124_114610911268.0Zinc fingerC2H2-type 12%3B atypical
HgeneZNF592chr15:85343208chr22:21965145ENST00000560079+10111153_117610911268.0Zinc fingerC2H2-type 13
TgeneUBE2L3chr15:85343208chr22:21965145ENST00000342192142_14941155.0DomainUBC core
TgeneUBE2L3chr15:85343208chr22:21965145ENST00000458578142_14999213.0DomainUBC core
TgeneUBE2L3chr15:85343208chr22:21965145ENST00000545681032_1499123.0DomainUBC core


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Fusion Gene Sequence for ZNF592-UBE2L3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102496_102496_1_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000299927_UBE2L3_chr22_21965145_ENST00000342192_length(transcript)=6002nt_BP=3295nt
CAGCCCTTGCCAGCATCCAGCCATGGGGGATATGAAAACCCCAGATTTTGATGACCTTCTGGCTGCCTTTGACATCCCAGACCCCACCAG
CCTTGATGCCAAGGAGGCCATCCAGACACCCAGTGAGGAGAATGAGAGTCCCCTCAAACCTCCAGGCATATGTATGGATGAAAGTGTGTC
CTTGTCTCACTCAGGATCAGCCCCCGATGTGCCGGCCGTGAGTGTCATTGTCAAGAACACCAGCCGCCAGGAGTCATTTGAAGCGGAGAA
AGACCACATTACTCCCAGTCTCCTACACAATGGATTCCGGGGCTCAGATCTGCCTCCAGATCCCCACAACTGTGGGAAATTTGATTCTAC
TTTTATGAATGGAGACAGTGCCAGGAGTTTCCCTGGCAAACTGGAGCCTCCCAAGTCAGAGCCATTACCCACCTTCAACCAGTTCAGTCC
AATCTCCAGCCCAGAACCTGAGGATCCCATCAAAGATAACGGATTTGGGATAAAGCCCAAACACTCTGACAGTTATTTCCCACCCCCTCT
TGGGTGCGGGGCTGTGGGAGGCCCAGTCCTGGAGGCTCTGGCTAAGTTTCCGGTTCCAGAGCTGCATATGTTTGATCATTTTTGTAAGAA
AGAACCCAAGCCAGAACCCCTGCCCTTGGGGAGCCAGCAGGAACACGAGCAAAGTGGGCAGAACACAGTGGAACCTCACAAGGATCCGGA
TGCCACTCGATTCTTCGGGGAAGCTTTGGAGTTCAACAGCCATCCTAGCAACAGTATTGGAGAGTCCAAGGGGCTTGCCCGGGAGCTTGG
TACCTGCTCATCAGTCCCCCCTAGGCAGCGTCTAAAGCCAGCTCATTCCAAGCTGTCCTCTTGTGTGGCAGCCTTGGTGGCCTTGCAGGC
CAAAAGAGTGGCTAGTGTCACTAAGGAGGATCAGCCTGGCCACACAAAGGATCTCTCAGGGCCCACTAAAGAGAGTTCTAAAGGTAGCCC
CAAAATGCCCAAGTCACCAAAGAGTCCCCGGAGCCCTCTGGAGGCCACTAGAAAAAGTATCAAGCCATCGGACAGCCCTCGTAGCATCTG
CAGTGACAGCAGCAGCAAAGGCTCACCGTCTGTGGCTGCCAGCTCCCCACCAGCAATTCCCAAAGTGAGAATCAAAACCATTAAGACATC
ATCAGGGGAAATCAAACGGACTGTCACAAGGATCCTGCCAGATCCTGATGATCCAAGTAAGTCCCCTGTTGGGTCACCTCTAGGGAGCGC
CATTGCAGAGGCCCCCAGCGAGATGCCAGGGGATGAGGTGCCTGTGGAAGAGCACTTTCCTGAGGCAGGCACAAATTCAGGGAGCCCCCA
GGGGGCCAGGAAAGGGGACGAGAGCATGACAAAGGCCAGTGACTCGTCATCTCCCAGCTGCAGTTCTGGGCCCCGGGTCCCAAAGGGGGC
TGCCCCAGGCTCACAGACAGGCAAGAAGCAACAGAGCACAGCACTGCAGGCATCCACCCTGGCCCCTGCCAACCTCCTGCCCAAAGCCGT
GCACTTGGCCAACCTGAACCTCGTCCCCCACAGTGTTGCTGCATCAGTGACAGCCAAGTCTTCAGTGCAAAGACGGAGCCAGCCACAGCT
TACACAAATGTCGGTGCCCCTGGTCCACCAGGTGAAAAAGGCTGCCCCACTGATTGTAGAGGTCTTCAACAAGGTCCTTCACAGCTCCAA
CCCCGTGCCCCTCTATGCGCCAAATCTCAGCCCGCCTGCGGACAGCAGGATCCACGTGCCGGCCAGTGGGTACTGCTGCCTGGAGTGTGG
AGACGCATTTGCCTTAGAGAAGAGCCTGAGCCAGCACTATGGCCGGCGGAGCGTCCACATTGAGGTACTGTGCACACTGTGCTCCAAGAC
GCTGCTCTTCTTCAACAAGTGCAGCCTGCTCCGGCACGCCCGTGACCACAAGAGCAAGGGGCTCGTCATGCAGTGTTCCCAGCTGCTGGT
GAAGCCTATCTCTGCGGACCAAATGTTCGTGTCGGCCCCTGTGAACTCCACGGCACCAGCAGCCCCAGCCCCTTCATCCTCTCCCAAACA
TGGCCTCACTTCGGGCAGTGCCAGTCCCCCTCCTCCAGCCTTGCCACTCTACCCAGACCCTGTGAGGCTCATCCGGTACTCAATCAAGTG
TCTTGAATGTCACAAGCAGATGCGGGACTACATGGTCCTGGCTGCACATTTCCAGAGGACAACAGAGGAGACAGAGGGGCTGACCTGCCA
GGTATGCCAAATGCTGCTGCCCAACCAGTGCAGTTTCTGTGCCCACCAGCGGATTCATGCACACAAGTCCCCCTACTGCTGCCCGGAGTG
TGGGGTCCTCTGCCGCTCTGCCTACTTCCAGACCCATGTAAAGGAGAATTGCCTGCACTATGCCCGCAAGGTGGGCTACAGGTGCATCCA
CTGTGGTGTCGTCCACCTGACCTTGGCCTTGCTGAAAAGCCACATCCAGGAGCGACACTGCCAGGTTTTCCACAAATGTGCATTCTGCCC
CATGGCCTTCAAGACTGCCAGCAGCACTGCAGACCACAGTGCCACCCAGCACCCCACCCAGCCCCACAGACCCTCCCAGCTCATTTATAA
GTGCTCCTGTGAAATGGTCTTCAACAAGAAGAGGCACATTCAGCAGCATTTTTACCAGAATGTCAGCAAGACGCAGGTGGGCGTCTTCAA
GTGCCCTGAGTGCCCACTCTTGTTCGTGCAGAAGCCGGAGTTGATGCAACACGTCAAGAGCACCCACGGTGTTCCCCGAAATGTGGACGA
GCTGTCAAGCCTCCAGTCTTCAGCGGACACATCCTCAAGCCGCCCTGGCTCTCGAGTTCCCACTGAGCCACCAGCCACTAGTGTGGCTGC
TCGGAGCAGCTCCCTGCCTTCTGGCCGCTGGGGTAGGCCTGAAGCCCACCGCAGGGTGGAAGCCAGGCCGCGGCTGAGGAACACTGGCTG
GACCTGCCAGGAGTGCCAGGAGTGGGTTCCAGATCGGGAGAGCTACGTGTCCCACATGAAAAAGAGCCACGGTCGGACATTGAAGCGGTA
CCCATGCCGGCAGTGTGAACAGTCCTTCCACACCCCCAACAGCCTGCGCAAACACATCCGCAACAACCATGACACAGTAAAGAAGTTCTA
CACCTGCGGGTACTGCACAGAGGACAGCCCCAGCTTTCCTCGGCCCTCCCTTCTGGAGAGCCACATCAGCCTTATGCATGGCATCAGAAA
CCCTGATTTGAGCCAGACGTCCAAAGTGAAACCTCCGGGTGGACATTCCCCTCAGGACAACCCTCCATATGATAAGGGAGCCTTCAGAAT
CGAAATCAACTTTCCAGCAGAGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGG
GCAGGTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGTAATCCAGTCCCTCATAGCACTGGTGAA
TGACCCCCAGCCTGAGCACCCGCTTCGGGCTGACCTAGCTGAAGAATACTCTAAGGACCGTAAAAAATTCTGTAAGAATGCTGAAGAGTT
TACAAAGAAATATGGGGAAAAGCGACCTGTGGACTAAAATCTGCCACGATTGGTTCCAGCAAGTGTGAGCAGAGACCCCGTGCAGTGCAT
TCAGACACCCCGCAAAGCAGGACTCTGTGGAAATTGACACGTGCCACCGCCTGGCGTTCGCTTGTGGCAGTTACTAACTTTCTACAGTTT
TCTTAATCAAAAGTGGTCTAGGTAACCTGTAAAGAAAGGATTAAAAATTTAAGATGTTCTAGTTCTGCTCTCTTTGTTTTAAAAATCACT
GCTTCAATCTACTTCAAAAGAATGGTGTTTCTTTTCTTGTCCAATTTTATCCAAAATCTTCAAGTTACATTTAACCCATAAGGTTTAAAA
AAAAGGAAAAAAAACGGTTGTGGTTCCCTTTCTTCCCTACCCTTGCCACTCCCACTTTCTGGCACCGAGTTTATTTTTCACTTACTTACT
TCCCCAGACCCCGGGCTCGCCTCCACAAAGGAGAAAAGACTGCCCTGGCGGTCCTGGTGGCTTTTCTTAGCATGTGTGGCACTGTTGCCC
AGTGTGGGAGTTGGTTTAAATTCTCCTGACTCCAGTTTATAACATCCTTTTAAAAAATTTAAAAACAAACAGCCACACCCCTCCTCCAGT
CCTTCTCCTCAGTTCTTGTGTGAAACTCCAGCTGATGTTACCACAGTAACATCAGTTAATTGGGCAAGCCCTGATGTCAGTGTGTGTAAC
TGACCTCTGGCCTGGCCTGCACAGAGAAGCCCTATAATCACAGGTCTGTGGTGGCCCCGAAATGGGGGGCCTGCTAGTCAGGAGGATGCT
GTGCACACTGTGTGTGATGAATCTCGCCAGAAAGGCTCCTGAGGTCCCAGGTTGGCACTTCTCCCTGCAGCCATTGTAGAAGATCTGCTG
GTCCTTGCAGGCAAAGCTACAGCCAGAATGTCCGTTTGAAACTCCTAGCTCATCTGTCACCGAGCTTCATCCGAATGTGCCACGGAGCTT
GCTCTCCACTTCCTCCGTGCAGTGGCCCTGCCACAGCCCTCCCTCGGCACACTTTGACCCTTTGTAGGATTGGAATTAGCAGGACTCGGC
TATTTAAAGCACCAGTCTGGGGTCGCCTGGGCCCCTGCTGACCCCCTCCTCCAGAGCAGCCAGCCCAGCCCGGGAACAAGACGGACTTCC
TCTCCCTTCGGACTCACAGCCTTTGCAGAGTCAAGCTCCACTTGAAGCTCACTCAGTAATATCCTTTCAATGTGTTTTATATTGTTTTGA
CTGCCTTTTTTTGTAGAAATAAAAATTGACCTTAGAATTTATCGTCAGATAAACTTGTAAAGATTTGAATATTAATGTCTTTTCAAGGCA
AATGGGATTGTCCCCGCACTAGTAGAGAATCCATGTCGCTCTGACACCCCAAGGAAGCCGACGATCCAAATGCCGTGTGTCACCAACCCC
GCTTCTGCCACTGGCGGCTTCCCTTCTTGGCTCTTGGGGGGGACTAGATCCTGTGGAGAAGATGACTTAAACTTTGCTTTTTGTTTTAAT
TTTAATTCTATAACTTGAGATCTTTCCGGGGCCTACAGGCGTGTAAGACAGCTTGGTCTGGTCTGTGCAGAAGTGGGGAGTGATGGGCAG
GTTCGGCAGCCTAACATTGTTCAGGCGCATGGCCCCTGCGGTGTGTACACGAACTCGGCTTCTTTTGTCCTAGGTACGCCAAGGGCAGGT
TTCTGGAGACTCCCTTGTGCCCGGGATGGCAAGGGCACCGGGCTGGCGTTTCCACATCTGTCTTCATTAGCAGAAAAGTGATGATGGATT
TTATTTCACTCACACTCCAGTTTGTAATAAAATGCCAAATTCTGTCAGCTATCCAAACAAGCCACCATTTGTTCTTGTTGCTTCTCTGGA
TCCAGAAATGTTGCCATTCTTGGAAACTGTCCCATTGCTTCGTATTTCTGCCAACGTAGCTCTGCCTGCCTGTCAACCCCTCACTGCACT
CTGCTCATCACGGGAGGATACCTGTGTGCCGGCAGCCCCTCAGGGACTCTCAGCCCTGGCACTGGCACCCCAGGGTTGGCCCCGTCAGCA
GAGGCTTGGCTTTCGAGCCAGTGGGTGTCTCTCCTTTGGGCCTGGGCGGCTTGCTCCTGCCAGCCATGCCTTCAGGGTAGGCTCTGAGCA
AGCTGGCGAACAGCCCTGGCTGCTCCAAAACCAAAAAGCTGGGTCCTCTGGAGGAGGGGCGAGCTGTGGAGCAGCCACCCACTGCTGCCC
CAAGCTCACTCAGGAATTCACACCCGCCTGGTTTCTTGAAGTGTGCTGGGTCCTTCCCTCTGCTCCCTACTCCCCACCACGGCAGAGAAT

>102496_102496_1_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000299927_UBE2L3_chr22_21965145_ENST00000342192_length(amino acids)=1204AA_BP=1088
MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKPPGICMDESVSLSHSGSAPDVPAVSVIVKNTSRQESFEAEKDHITPSL
LHNGFRGSDLPPDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIKPKHSDSYFPPPLGCGAVGG
PVLEALAKFPVPELHMFDHFCKKEPKPEPLPLGSQQEHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPP
RQRLKPAHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPLEATRKSIKPSDSPRSICSDSSSKG
SPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGARKGDE
SMTKASDSSSPSCSSGPRVPKGAAPGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPHSVAASVTAKSSVQRRSQPQLTQMSVPL
VHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKC
SLLRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSPKHGLTSGSASPPPPALPLYPDPVRLIRYSIKCLECHKQM
RDYMVLAAHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKVGYRCIHCGVVHLT
LALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQPHRPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLL
FVQKPELMQHVKSTHGVPRNVDELSSLQSSADTSSSRPGSRVPTEPPATSVAARSSSLPSGRWGRPEAHRRVEARPRLRNTGWTCQECQE
WVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLSQTS
KVKPPGGHSPQDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP

--------------------------------------------------------------
>102496_102496_2_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000299927_UBE2L3_chr22_21965145_ENST00000458578_length(transcript)=4220nt_BP=3295nt
CAGCCCTTGCCAGCATCCAGCCATGGGGGATATGAAAACCCCAGATTTTGATGACCTTCTGGCTGCCTTTGACATCCCAGACCCCACCAG
CCTTGATGCCAAGGAGGCCATCCAGACACCCAGTGAGGAGAATGAGAGTCCCCTCAAACCTCCAGGCATATGTATGGATGAAAGTGTGTC
CTTGTCTCACTCAGGATCAGCCCCCGATGTGCCGGCCGTGAGTGTCATTGTCAAGAACACCAGCCGCCAGGAGTCATTTGAAGCGGAGAA
AGACCACATTACTCCCAGTCTCCTACACAATGGATTCCGGGGCTCAGATCTGCCTCCAGATCCCCACAACTGTGGGAAATTTGATTCTAC
TTTTATGAATGGAGACAGTGCCAGGAGTTTCCCTGGCAAACTGGAGCCTCCCAAGTCAGAGCCATTACCCACCTTCAACCAGTTCAGTCC
AATCTCCAGCCCAGAACCTGAGGATCCCATCAAAGATAACGGATTTGGGATAAAGCCCAAACACTCTGACAGTTATTTCCCACCCCCTCT
TGGGTGCGGGGCTGTGGGAGGCCCAGTCCTGGAGGCTCTGGCTAAGTTTCCGGTTCCAGAGCTGCATATGTTTGATCATTTTTGTAAGAA
AGAACCCAAGCCAGAACCCCTGCCCTTGGGGAGCCAGCAGGAACACGAGCAAAGTGGGCAGAACACAGTGGAACCTCACAAGGATCCGGA
TGCCACTCGATTCTTCGGGGAAGCTTTGGAGTTCAACAGCCATCCTAGCAACAGTATTGGAGAGTCCAAGGGGCTTGCCCGGGAGCTTGG
TACCTGCTCATCAGTCCCCCCTAGGCAGCGTCTAAAGCCAGCTCATTCCAAGCTGTCCTCTTGTGTGGCAGCCTTGGTGGCCTTGCAGGC
CAAAAGAGTGGCTAGTGTCACTAAGGAGGATCAGCCTGGCCACACAAAGGATCTCTCAGGGCCCACTAAAGAGAGTTCTAAAGGTAGCCC
CAAAATGCCCAAGTCACCAAAGAGTCCCCGGAGCCCTCTGGAGGCCACTAGAAAAAGTATCAAGCCATCGGACAGCCCTCGTAGCATCTG
CAGTGACAGCAGCAGCAAAGGCTCACCGTCTGTGGCTGCCAGCTCCCCACCAGCAATTCCCAAAGTGAGAATCAAAACCATTAAGACATC
ATCAGGGGAAATCAAACGGACTGTCACAAGGATCCTGCCAGATCCTGATGATCCAAGTAAGTCCCCTGTTGGGTCACCTCTAGGGAGCGC
CATTGCAGAGGCCCCCAGCGAGATGCCAGGGGATGAGGTGCCTGTGGAAGAGCACTTTCCTGAGGCAGGCACAAATTCAGGGAGCCCCCA
GGGGGCCAGGAAAGGGGACGAGAGCATGACAAAGGCCAGTGACTCGTCATCTCCCAGCTGCAGTTCTGGGCCCCGGGTCCCAAAGGGGGC
TGCCCCAGGCTCACAGACAGGCAAGAAGCAACAGAGCACAGCACTGCAGGCATCCACCCTGGCCCCTGCCAACCTCCTGCCCAAAGCCGT
GCACTTGGCCAACCTGAACCTCGTCCCCCACAGTGTTGCTGCATCAGTGACAGCCAAGTCTTCAGTGCAAAGACGGAGCCAGCCACAGCT
TACACAAATGTCGGTGCCCCTGGTCCACCAGGTGAAAAAGGCTGCCCCACTGATTGTAGAGGTCTTCAACAAGGTCCTTCACAGCTCCAA
CCCCGTGCCCCTCTATGCGCCAAATCTCAGCCCGCCTGCGGACAGCAGGATCCACGTGCCGGCCAGTGGGTACTGCTGCCTGGAGTGTGG
AGACGCATTTGCCTTAGAGAAGAGCCTGAGCCAGCACTATGGCCGGCGGAGCGTCCACATTGAGGTACTGTGCACACTGTGCTCCAAGAC
GCTGCTCTTCTTCAACAAGTGCAGCCTGCTCCGGCACGCCCGTGACCACAAGAGCAAGGGGCTCGTCATGCAGTGTTCCCAGCTGCTGGT
GAAGCCTATCTCTGCGGACCAAATGTTCGTGTCGGCCCCTGTGAACTCCACGGCACCAGCAGCCCCAGCCCCTTCATCCTCTCCCAAACA
TGGCCTCACTTCGGGCAGTGCCAGTCCCCCTCCTCCAGCCTTGCCACTCTACCCAGACCCTGTGAGGCTCATCCGGTACTCAATCAAGTG
TCTTGAATGTCACAAGCAGATGCGGGACTACATGGTCCTGGCTGCACATTTCCAGAGGACAACAGAGGAGACAGAGGGGCTGACCTGCCA
GGTATGCCAAATGCTGCTGCCCAACCAGTGCAGTTTCTGTGCCCACCAGCGGATTCATGCACACAAGTCCCCCTACTGCTGCCCGGAGTG
TGGGGTCCTCTGCCGCTCTGCCTACTTCCAGACCCATGTAAAGGAGAATTGCCTGCACTATGCCCGCAAGGTGGGCTACAGGTGCATCCA
CTGTGGTGTCGTCCACCTGACCTTGGCCTTGCTGAAAAGCCACATCCAGGAGCGACACTGCCAGGTTTTCCACAAATGTGCATTCTGCCC
CATGGCCTTCAAGACTGCCAGCAGCACTGCAGACCACAGTGCCACCCAGCACCCCACCCAGCCCCACAGACCCTCCCAGCTCATTTATAA
GTGCTCCTGTGAAATGGTCTTCAACAAGAAGAGGCACATTCAGCAGCATTTTTACCAGAATGTCAGCAAGACGCAGGTGGGCGTCTTCAA
GTGCCCTGAGTGCCCACTCTTGTTCGTGCAGAAGCCGGAGTTGATGCAACACGTCAAGAGCACCCACGGTGTTCCCCGAAATGTGGACGA
GCTGTCAAGCCTCCAGTCTTCAGCGGACACATCCTCAAGCCGCCCTGGCTCTCGAGTTCCCACTGAGCCACCAGCCACTAGTGTGGCTGC
TCGGAGCAGCTCCCTGCCTTCTGGCCGCTGGGGTAGGCCTGAAGCCCACCGCAGGGTGGAAGCCAGGCCGCGGCTGAGGAACACTGGCTG
GACCTGCCAGGAGTGCCAGGAGTGGGTTCCAGATCGGGAGAGCTACGTGTCCCACATGAAAAAGAGCCACGGTCGGACATTGAAGCGGTA
CCCATGCCGGCAGTGTGAACAGTCCTTCCACACCCCCAACAGCCTGCGCAAACACATCCGCAACAACCATGACACAGTAAAGAAGTTCTA
CACCTGCGGGTACTGCACAGAGGACAGCCCCAGCTTTCCTCGGCCCTCCCTTCTGGAGAGCCACATCAGCCTTATGCATGGCATCAGAAA
CCCTGATTTGAGCCAGACGTCCAAAGTGAAACCTCCGGGTGGACATTCCCCTCAGGACAACCCTCCATATGATAAGGGAGCCTTCAGAAT
CGAAATCAACTTTCCAGCAGAGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGG
GCAGGTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGTAATCCAGTCCCTCATAGCACTGGTGAA
TGACCCCCAGCCTGAGCACCCGCTTCGGGCTGACCTAGCTGAAGAATACTCTAAGGACCGTAAAAAATTCTGTAAGAATGCTGAAGAGTT
TACAAAGAAATATGGGGAAAAGCGACCTGTGGACTAAAATCTGCCACGATTGGTTCCAGCAAGTGTGAGCAGAGACCCCGTGCAGTGCAT
TCAGACACCCCGCAAAGCAGGACTCTGTGGAAATTGACACGTGCCACCGCCTGGCGTTCGCTTGTGGCAGTTACTAACTTTCTACAGTTT
TCTTAATCAAAAGTGGTCTAGGTAACCTGTAAAGAAAGGATTAAAAATTTAAGATGTTCTAGTTCTGCTCTCTTTGTTTTAAAAATCACT
GCTTCAATCTACTTCAAAAGAATGGTGTTTCTTTTCTTGTCCAATTTTATCCAAAATCTTCAAGTTACATTTAACCCATAAGGTTTAAAA
AAAAGGAAAAAAAACGGTTGTGGTTCCCTTTCTTCCCTACCCTTGCCACTCCCACTTTCTGGCACCGAGTTTATTTTTCACTTACTTACT
TCCCCAGACCCCGGGCTCGCCTCCACAAAGGAGAAAAGACTGCCCTGGCGGTCCTGGTGGCTTTTCTTAGCATGTGTGGCACTGTTGCCC

>102496_102496_2_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000299927_UBE2L3_chr22_21965145_ENST00000458578_length(amino acids)=1204AA_BP=1088
MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKPPGICMDESVSLSHSGSAPDVPAVSVIVKNTSRQESFEAEKDHITPSL
LHNGFRGSDLPPDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIKPKHSDSYFPPPLGCGAVGG
PVLEALAKFPVPELHMFDHFCKKEPKPEPLPLGSQQEHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPP
RQRLKPAHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPLEATRKSIKPSDSPRSICSDSSSKG
SPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGARKGDE
SMTKASDSSSPSCSSGPRVPKGAAPGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPHSVAASVTAKSSVQRRSQPQLTQMSVPL
VHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKC
SLLRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSPKHGLTSGSASPPPPALPLYPDPVRLIRYSIKCLECHKQM
RDYMVLAAHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKVGYRCIHCGVVHLT
LALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQPHRPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLL
FVQKPELMQHVKSTHGVPRNVDELSSLQSSADTSSSRPGSRVPTEPPATSVAARSSSLPSGRWGRPEAHRRVEARPRLRNTGWTCQECQE
WVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLSQTS
KVKPPGGHSPQDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP

--------------------------------------------------------------
>102496_102496_3_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000299927_UBE2L3_chr22_21965145_ENST00000545681_length(transcript)=4317nt_BP=3295nt
CAGCCCTTGCCAGCATCCAGCCATGGGGGATATGAAAACCCCAGATTTTGATGACCTTCTGGCTGCCTTTGACATCCCAGACCCCACCAG
CCTTGATGCCAAGGAGGCCATCCAGACACCCAGTGAGGAGAATGAGAGTCCCCTCAAACCTCCAGGCATATGTATGGATGAAAGTGTGTC
CTTGTCTCACTCAGGATCAGCCCCCGATGTGCCGGCCGTGAGTGTCATTGTCAAGAACACCAGCCGCCAGGAGTCATTTGAAGCGGAGAA
AGACCACATTACTCCCAGTCTCCTACACAATGGATTCCGGGGCTCAGATCTGCCTCCAGATCCCCACAACTGTGGGAAATTTGATTCTAC
TTTTATGAATGGAGACAGTGCCAGGAGTTTCCCTGGCAAACTGGAGCCTCCCAAGTCAGAGCCATTACCCACCTTCAACCAGTTCAGTCC
AATCTCCAGCCCAGAACCTGAGGATCCCATCAAAGATAACGGATTTGGGATAAAGCCCAAACACTCTGACAGTTATTTCCCACCCCCTCT
TGGGTGCGGGGCTGTGGGAGGCCCAGTCCTGGAGGCTCTGGCTAAGTTTCCGGTTCCAGAGCTGCATATGTTTGATCATTTTTGTAAGAA
AGAACCCAAGCCAGAACCCCTGCCCTTGGGGAGCCAGCAGGAACACGAGCAAAGTGGGCAGAACACAGTGGAACCTCACAAGGATCCGGA
TGCCACTCGATTCTTCGGGGAAGCTTTGGAGTTCAACAGCCATCCTAGCAACAGTATTGGAGAGTCCAAGGGGCTTGCCCGGGAGCTTGG
TACCTGCTCATCAGTCCCCCCTAGGCAGCGTCTAAAGCCAGCTCATTCCAAGCTGTCCTCTTGTGTGGCAGCCTTGGTGGCCTTGCAGGC
CAAAAGAGTGGCTAGTGTCACTAAGGAGGATCAGCCTGGCCACACAAAGGATCTCTCAGGGCCCACTAAAGAGAGTTCTAAAGGTAGCCC
CAAAATGCCCAAGTCACCAAAGAGTCCCCGGAGCCCTCTGGAGGCCACTAGAAAAAGTATCAAGCCATCGGACAGCCCTCGTAGCATCTG
CAGTGACAGCAGCAGCAAAGGCTCACCGTCTGTGGCTGCCAGCTCCCCACCAGCAATTCCCAAAGTGAGAATCAAAACCATTAAGACATC
ATCAGGGGAAATCAAACGGACTGTCACAAGGATCCTGCCAGATCCTGATGATCCAAGTAAGTCCCCTGTTGGGTCACCTCTAGGGAGCGC
CATTGCAGAGGCCCCCAGCGAGATGCCAGGGGATGAGGTGCCTGTGGAAGAGCACTTTCCTGAGGCAGGCACAAATTCAGGGAGCCCCCA
GGGGGCCAGGAAAGGGGACGAGAGCATGACAAAGGCCAGTGACTCGTCATCTCCCAGCTGCAGTTCTGGGCCCCGGGTCCCAAAGGGGGC
TGCCCCAGGCTCACAGACAGGCAAGAAGCAACAGAGCACAGCACTGCAGGCATCCACCCTGGCCCCTGCCAACCTCCTGCCCAAAGCCGT
GCACTTGGCCAACCTGAACCTCGTCCCCCACAGTGTTGCTGCATCAGTGACAGCCAAGTCTTCAGTGCAAAGACGGAGCCAGCCACAGCT
TACACAAATGTCGGTGCCCCTGGTCCACCAGGTGAAAAAGGCTGCCCCACTGATTGTAGAGGTCTTCAACAAGGTCCTTCACAGCTCCAA
CCCCGTGCCCCTCTATGCGCCAAATCTCAGCCCGCCTGCGGACAGCAGGATCCACGTGCCGGCCAGTGGGTACTGCTGCCTGGAGTGTGG
AGACGCATTTGCCTTAGAGAAGAGCCTGAGCCAGCACTATGGCCGGCGGAGCGTCCACATTGAGGTACTGTGCACACTGTGCTCCAAGAC
GCTGCTCTTCTTCAACAAGTGCAGCCTGCTCCGGCACGCCCGTGACCACAAGAGCAAGGGGCTCGTCATGCAGTGTTCCCAGCTGCTGGT
GAAGCCTATCTCTGCGGACCAAATGTTCGTGTCGGCCCCTGTGAACTCCACGGCACCAGCAGCCCCAGCCCCTTCATCCTCTCCCAAACA
TGGCCTCACTTCGGGCAGTGCCAGTCCCCCTCCTCCAGCCTTGCCACTCTACCCAGACCCTGTGAGGCTCATCCGGTACTCAATCAAGTG
TCTTGAATGTCACAAGCAGATGCGGGACTACATGGTCCTGGCTGCACATTTCCAGAGGACAACAGAGGAGACAGAGGGGCTGACCTGCCA
GGTATGCCAAATGCTGCTGCCCAACCAGTGCAGTTTCTGTGCCCACCAGCGGATTCATGCACACAAGTCCCCCTACTGCTGCCCGGAGTG
TGGGGTCCTCTGCCGCTCTGCCTACTTCCAGACCCATGTAAAGGAGAATTGCCTGCACTATGCCCGCAAGGTGGGCTACAGGTGCATCCA
CTGTGGTGTCGTCCACCTGACCTTGGCCTTGCTGAAAAGCCACATCCAGGAGCGACACTGCCAGGTTTTCCACAAATGTGCATTCTGCCC
CATGGCCTTCAAGACTGCCAGCAGCACTGCAGACCACAGTGCCACCCAGCACCCCACCCAGCCCCACAGACCCTCCCAGCTCATTTATAA
GTGCTCCTGTGAAATGGTCTTCAACAAGAAGAGGCACATTCAGCAGCATTTTTACCAGAATGTCAGCAAGACGCAGGTGGGCGTCTTCAA
GTGCCCTGAGTGCCCACTCTTGTTCGTGCAGAAGCCGGAGTTGATGCAACACGTCAAGAGCACCCACGGTGTTCCCCGAAATGTGGACGA
GCTGTCAAGCCTCCAGTCTTCAGCGGACACATCCTCAAGCCGCCCTGGCTCTCGAGTTCCCACTGAGCCACCAGCCACTAGTGTGGCTGC
TCGGAGCAGCTCCCTGCCTTCTGGCCGCTGGGGTAGGCCTGAAGCCCACCGCAGGGTGGAAGCCAGGCCGCGGCTGAGGAACACTGGCTG
GACCTGCCAGGAGTGCCAGGAGTGGGTTCCAGATCGGGAGAGCTACGTGTCCCACATGAAAAAGAGCCACGGTCGGACATTGAAGCGGTA
CCCATGCCGGCAGTGTGAACAGTCCTTCCACACCCCCAACAGCCTGCGCAAACACATCCGCAACAACCATGACACAGTAAAGAAGTTCTA
CACCTGCGGGTACTGCACAGAGGACAGCCCCAGCTTTCCTCGGCCCTCCCTTCTGGAGAGCCACATCAGCCTTATGCATGGCATCAGAAA
CCCTGATTTGAGCCAGACGTCCAAAGTGAAACCTCCGGGTGGACATTCCCCTCAGGACAACCCTCCATATGATAAGGGAGCCTTCAGAAT
CGAAATCAACTTTCCAGCAGAGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGG
GCAGGTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGTAATCCAGTCCCTCATAGCACTGGTGAA
TGACCCCCAGCCTGAGCACCCGCTTCGGGCTGACCTAGCTGAAGAATACTCTAAGGACCGTAAAAAATTCTGTAAGAATGCTGAAGAGTT
TACAAAGAAATATGGGGAAAAGCGACCTGTGGACTAAAATCTGCCACGATTGGTTCCAGCAAGTGTGAGCAGAGACCCCGTGCAGTGCAT
TCAGACACCCCGCAAAGCAGGACTCTGTGGAAATTGACACGTGCCACCGCCTGGCGTTCGCTTGTGGCAGTTACTAACTTTCTACAGTTT
TCTTAATCAAAAGTGGTCTAGGTAACCTGTAAAGAAAGGATTAAAAATTTAAGATGTTCTAGTTCTGCTCTCTTTGTTTTAAAAATCACT
GCTTCAATCTACTTCAAAAGAATGGTGTTTCTTTTCTTGTCCAATTTTATCCAAAATCTTCAAGTTACATTTAACCCATAAGGTTTAAAA
AAAAGGAAAAAAAACGGTTGTGGTTCCCTTTCTTCCCTACCCTTGCCACTCCCACTTTCTGGCACCGAGTTTATTTTTCACTTACTTACT
TCCCCAGACCCCGGGCTCGCCTCCACAAAGGAGAAAAGACTGCCCTGGCGGTCCTGGTGGCTTTTCTTAGCATGTGTGGCACTGTTGCCC
AGTGTGGGAGTTGGTTTAAATTCTCCTGACTCCAGTTTATAACATCCTTTTAAAAAATTTAAAAACAAACAGCCACACCCCTCCTCCAGT

>102496_102496_3_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000299927_UBE2L3_chr22_21965145_ENST00000545681_length(amino acids)=1204AA_BP=1088
MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKPPGICMDESVSLSHSGSAPDVPAVSVIVKNTSRQESFEAEKDHITPSL
LHNGFRGSDLPPDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIKPKHSDSYFPPPLGCGAVGG
PVLEALAKFPVPELHMFDHFCKKEPKPEPLPLGSQQEHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPP
RQRLKPAHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPLEATRKSIKPSDSPRSICSDSSSKG
SPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGARKGDE
SMTKASDSSSPSCSSGPRVPKGAAPGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPHSVAASVTAKSSVQRRSQPQLTQMSVPL
VHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKC
SLLRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSPKHGLTSGSASPPPPALPLYPDPVRLIRYSIKCLECHKQM
RDYMVLAAHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKVGYRCIHCGVVHLT
LALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQPHRPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLL
FVQKPELMQHVKSTHGVPRNVDELSSLQSSADTSSSRPGSRVPTEPPATSVAARSSSLPSGRWGRPEAHRRVEARPRLRNTGWTCQECQE
WVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLSQTS
KVKPPGGHSPQDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP

--------------------------------------------------------------
>102496_102496_4_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000560079_UBE2L3_chr22_21965145_ENST00000342192_length(transcript)=6268nt_BP=3561nt
CTGGCCTGCAGTCGCCGCCGCCGCCGCCAGGTGGTGTTTGGACTCTAGACCATGTGCCTAGGTAGAAGTTTTTCCTTTCTCCGCAGCTCT
GCTCCCCTAGCAACGCTCGCCACACCCTTGTTTTGAGATCCTCTCTAAGGAGCGGAGAGTTTAATAGGCAAGAAGGAAGGGAGAAGACAG
AAGGAAGACGCTCCCCCGTACGGAGACAGAGGGAGGGGGGGCTCCAAAGCCGAAAGAGGAGGTCCCTACCTGCCACGGATACCAGTCAGC
CCTTGCCAGCATCCAGCCATGGGGGATATGAAAACCCCAGATTTTGATGACCTTCTGGCTGCCTTTGACATCCCAGACCCCACCAGCCTT
GATGCCAAGGAGGCCATCCAGACACCCAGTGAGGAGAATGAGAGTCCCCTCAAACCTCCAGGCATATGTATGGATGAAAGTGTGTCCTTG
TCTCACTCAGGATCAGCCCCCGATGTGCCGGCCGTGAGTGTCATTGTCAAGAACACCAGCCGCCAGGAGTCATTTGAAGCGGAGAAAGAC
CACATTACTCCCAGTCTCCTACACAATGGATTCCGGGGCTCAGATCTGCCTCCAGATCCCCACAACTGTGGGAAATTTGATTCTACTTTT
ATGAATGGAGACAGTGCCAGGAGTTTCCCTGGCAAACTGGAGCCTCCCAAGTCAGAGCCATTACCCACCTTCAACCAGTTCAGTCCAATC
TCCAGCCCAGAACCTGAGGATCCCATCAAAGATAACGGATTTGGGATAAAGCCCAAACACTCTGACAGTTATTTCCCACCCCCTCTTGGG
TGCGGGGCTGTGGGAGGCCCAGTCCTGGAGGCTCTGGCTAAGTTTCCGGTTCCAGAGCTGCATATGTTTGATCATTTTTGTAAGAAAGAA
CCCAAGCCAGAACCCCTGCCCTTGGGGAGCCAGCAGGAACACGAGCAAAGTGGGCAGAACACAGTGGAACCTCACAAGGATCCGGATGCC
ACTCGATTCTTCGGGGAAGCTTTGGAGTTCAACAGCCATCCTAGCAACAGTATTGGAGAGTCCAAGGGGCTTGCCCGGGAGCTTGGTACC
TGCTCATCAGTCCCCCCTAGGCAGCGTCTAAAGCCAGCTCATTCCAAGCTGTCCTCTTGTGTGGCAGCCTTGGTGGCCTTGCAGGCCAAA
AGAGTGGCTAGTGTCACTAAGGAGGATCAGCCTGGCCACACAAAGGATCTCTCAGGGCCCACTAAAGAGAGTTCTAAAGGTAGCCCCAAA
ATGCCCAAGTCACCAAAGAGTCCCCGGAGCCCTCTGGAGGCCACTAGAAAAAGTATCAAGCCATCGGACAGCCCTCGTAGCATCTGCAGT
GACAGCAGCAGCAAAGGCTCACCGTCTGTGGCTGCCAGCTCCCCACCAGCAATTCCCAAAGTGAGAATCAAAACCATTAAGACATCATCA
GGGGAAATCAAACGGACTGTCACAAGGATCCTGCCAGATCCTGATGATCCAAGTAAGTCCCCTGTTGGGTCACCTCTAGGGAGCGCCATT
GCAGAGGCCCCCAGCGAGATGCCAGGGGATGAGGTGCCTGTGGAAGAGCACTTTCCTGAGGCAGGCACAAATTCAGGGAGCCCCCAGGGG
GCCAGGAAAGGGGACGAGAGCATGACAAAGGCCAGTGACTCGTCATCTCCCAGCTGCAGTTCTGGGCCCCGGGTCCCAAAGGGGGCTGCC
CCAGGCTCACAGACAGGCAAGAAGCAACAGAGCACAGCACTGCAGGCATCCACCCTGGCCCCTGCCAACCTCCTGCCCAAAGCCGTGCAC
TTGGCCAACCTGAACCTCGTCCCCCACAGTGTTGCTGCATCAGTGACAGCCAAGTCTTCAGTGCAAAGACGGAGCCAGCCACAGCTTACA
CAAATGTCGGTGCCCCTGGTCCACCAGGTGAAAAAGGCTGCCCCACTGATTGTAGAGGTCTTCAACAAGGTCCTTCACAGCTCCAACCCC
GTGCCCCTCTATGCGCCAAATCTCAGCCCGCCTGCGGACAGCAGGATCCACGTGCCGGCCAGTGGGTACTGCTGCCTGGAGTGTGGAGAC
GCATTTGCCTTAGAGAAGAGCCTGAGCCAGCACTATGGCCGGCGGAGCGTCCACATTGAGGTACTGTGCACACTGTGCTCCAAGACGCTG
CTCTTCTTCAACAAGTGCAGCCTGCTCCGGCACGCCCGTGACCACAAGAGCAAGGGGCTCGTCATGCAGTGTTCCCAGCTGCTGGTGAAG
CCTATCTCTGCGGACCAAATGTTCGTGTCGGCCCCTGTGAACTCCACGGCACCAGCAGCCCCAGCCCCTTCATCCTCTCCCAAACATGGC
CTCACTTCGGGCAGTGCCAGTCCCCCTCCTCCAGCCTTGCCACTCTACCCAGACCCTGTGAGGCTCATCCGGTACTCAATCAAGTGTCTT
GAATGTCACAAGCAGATGCGGGACTACATGGTCCTGGCTGCACATTTCCAGAGGACAACAGAGGAGACAGAGGGGCTGACCTGCCAGGTA
TGCCAAATGCTGCTGCCCAACCAGTGCAGTTTCTGTGCCCACCAGCGGATTCATGCACACAAGTCCCCCTACTGCTGCCCGGAGTGTGGG
GTCCTCTGCCGCTCTGCCTACTTCCAGACCCATGTAAAGGAGAATTGCCTGCACTATGCCCGCAAGGTGGGCTACAGGTGCATCCACTGT
GGTGTCGTCCACCTGACCTTGGCCTTGCTGAAAAGCCACATCCAGGAGCGACACTGCCAGGTTTTCCACAAATGTGCATTCTGCCCCATG
GCCTTCAAGACTGCCAGCAGCACTGCAGACCACAGTGCCACCCAGCACCCCACCCAGCCCCACAGACCCTCCCAGCTCATTTATAAGTGC
TCCTGTGAAATGGTCTTCAACAAGAAGAGGCACATTCAGCAGCATTTTTACCAGAATGTCAGCAAGACGCAGGTGGGCGTCTTCAAGTGC
CCTGAGTGCCCACTCTTGTTCGTGCAGAAGCCGGAGTTGATGCAACACGTCAAGAGCACCCACGGTGTTCCCCGAAATGTGGACGAGCTG
TCAAGCCTCCAGTCTTCAGCGGACACATCCTCAAGCCGCCCTGGCTCTCGAGTTCCCACTGAGCCACCAGCCACTAGTGTGGCTGCTCGG
AGCAGCTCCCTGCCTTCTGGCCGCTGGGGTAGGCCTGAAGCCCACCGCAGGGTGGAAGCCAGGCCGCGGCTGAGGAACACTGGCTGGACC
TGCCAGGAGTGCCAGGAGTGGGTTCCAGATCGGGAGAGCTACGTGTCCCACATGAAAAAGAGCCACGGTCGGACATTGAAGCGGTACCCA
TGCCGGCAGTGTGAACAGTCCTTCCACACCCCCAACAGCCTGCGCAAACACATCCGCAACAACCATGACACAGTAAAGAAGTTCTACACC
TGCGGGTACTGCACAGAGGACAGCCCCAGCTTTCCTCGGCCCTCCCTTCTGGAGAGCCACATCAGCCTTATGCATGGCATCAGAAACCCT
GATTTGAGCCAGACGTCCAAAGTGAAACCTCCGGGTGGACATTCCCCTCAGGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAA
ATCAACTTTCCAGCAGAGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAG
GTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGTAATCCAGTCCCTCATAGCACTGGTGAATGAC
CCCCAGCCTGAGCACCCGCTTCGGGCTGACCTAGCTGAAGAATACTCTAAGGACCGTAAAAAATTCTGTAAGAATGCTGAAGAGTTTACA
AAGAAATATGGGGAAAAGCGACCTGTGGACTAAAATCTGCCACGATTGGTTCCAGCAAGTGTGAGCAGAGACCCCGTGCAGTGCATTCAG
ACACCCCGCAAAGCAGGACTCTGTGGAAATTGACACGTGCCACCGCCTGGCGTTCGCTTGTGGCAGTTACTAACTTTCTACAGTTTTCTT
AATCAAAAGTGGTCTAGGTAACCTGTAAAGAAAGGATTAAAAATTTAAGATGTTCTAGTTCTGCTCTCTTTGTTTTAAAAATCACTGCTT
CAATCTACTTCAAAAGAATGGTGTTTCTTTTCTTGTCCAATTTTATCCAAAATCTTCAAGTTACATTTAACCCATAAGGTTTAAAAAAAA
GGAAAAAAAACGGTTGTGGTTCCCTTTCTTCCCTACCCTTGCCACTCCCACTTTCTGGCACCGAGTTTATTTTTCACTTACTTACTTCCC
CAGACCCCGGGCTCGCCTCCACAAAGGAGAAAAGACTGCCCTGGCGGTCCTGGTGGCTTTTCTTAGCATGTGTGGCACTGTTGCCCAGTG
TGGGAGTTGGTTTAAATTCTCCTGACTCCAGTTTATAACATCCTTTTAAAAAATTTAAAAACAAACAGCCACACCCCTCCTCCAGTCCTT
CTCCTCAGTTCTTGTGTGAAACTCCAGCTGATGTTACCACAGTAACATCAGTTAATTGGGCAAGCCCTGATGTCAGTGTGTGTAACTGAC
CTCTGGCCTGGCCTGCACAGAGAAGCCCTATAATCACAGGTCTGTGGTGGCCCCGAAATGGGGGGCCTGCTAGTCAGGAGGATGCTGTGC
ACACTGTGTGTGATGAATCTCGCCAGAAAGGCTCCTGAGGTCCCAGGTTGGCACTTCTCCCTGCAGCCATTGTAGAAGATCTGCTGGTCC
TTGCAGGCAAAGCTACAGCCAGAATGTCCGTTTGAAACTCCTAGCTCATCTGTCACCGAGCTTCATCCGAATGTGCCACGGAGCTTGCTC
TCCACTTCCTCCGTGCAGTGGCCCTGCCACAGCCCTCCCTCGGCACACTTTGACCCTTTGTAGGATTGGAATTAGCAGGACTCGGCTATT
TAAAGCACCAGTCTGGGGTCGCCTGGGCCCCTGCTGACCCCCTCCTCCAGAGCAGCCAGCCCAGCCCGGGAACAAGACGGACTTCCTCTC
CCTTCGGACTCACAGCCTTTGCAGAGTCAAGCTCCACTTGAAGCTCACTCAGTAATATCCTTTCAATGTGTTTTATATTGTTTTGACTGC
CTTTTTTTGTAGAAATAAAAATTGACCTTAGAATTTATCGTCAGATAAACTTGTAAAGATTTGAATATTAATGTCTTTTCAAGGCAAATG
GGATTGTCCCCGCACTAGTAGAGAATCCATGTCGCTCTGACACCCCAAGGAAGCCGACGATCCAAATGCCGTGTGTCACCAACCCCGCTT
CTGCCACTGGCGGCTTCCCTTCTTGGCTCTTGGGGGGGACTAGATCCTGTGGAGAAGATGACTTAAACTTTGCTTTTTGTTTTAATTTTA
ATTCTATAACTTGAGATCTTTCCGGGGCCTACAGGCGTGTAAGACAGCTTGGTCTGGTCTGTGCAGAAGTGGGGAGTGATGGGCAGGTTC
GGCAGCCTAACATTGTTCAGGCGCATGGCCCCTGCGGTGTGTACACGAACTCGGCTTCTTTTGTCCTAGGTACGCCAAGGGCAGGTTTCT
GGAGACTCCCTTGTGCCCGGGATGGCAAGGGCACCGGGCTGGCGTTTCCACATCTGTCTTCATTAGCAGAAAAGTGATGATGGATTTTAT
TTCACTCACACTCCAGTTTGTAATAAAATGCCAAATTCTGTCAGCTATCCAAACAAGCCACCATTTGTTCTTGTTGCTTCTCTGGATCCA
GAAATGTTGCCATTCTTGGAAACTGTCCCATTGCTTCGTATTTCTGCCAACGTAGCTCTGCCTGCCTGTCAACCCCTCACTGCACTCTGC
TCATCACGGGAGGATACCTGTGTGCCGGCAGCCCCTCAGGGACTCTCAGCCCTGGCACTGGCACCCCAGGGTTGGCCCCGTCAGCAGAGG
CTTGGCTTTCGAGCCAGTGGGTGTCTCTCCTTTGGGCCTGGGCGGCTTGCTCCTGCCAGCCATGCCTTCAGGGTAGGCTCTGAGCAAGCT
GGCGAACAGCCCTGGCTGCTCCAAAACCAAAAAGCTGGGTCCTCTGGAGGAGGGGCGAGCTGTGGAGCAGCCACCCACTGCTGCCCCAAG
CTCACTCAGGAATTCACACCCGCCTGGTTTCTTGAAGTGTGCTGGGTCCTTCCCTCTGCTCCCTACTCCCCACCACGGCAGAGAATAGGC

>102496_102496_4_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000560079_UBE2L3_chr22_21965145_ENST00000342192_length(amino acids)=1217AA_BP=1101
MPRIPVSPCQHPAMGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKPPGICMDESVSLSHSGSAPDVPAVSVIVKNTSRQE
SFEAEKDHITPSLLHNGFRGSDLPPDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIKPKHSDS
YFPPPLGCGAVGGPVLEALAKFPVPELHMFDHFCKKEPKPEPLPLGSQQEHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKG
LARELGTCSSVPPRQRLKPAHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPLEATRKSIKPSD
SPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGT
NSGSPQGARKGDESMTKASDSSSPSCSSGPRVPKGAAPGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPHSVAASVTAKSSVQR
RSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLC
TLCSKTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSPKHGLTSGSASPPPPALPLYPDPVRLI
RYSIKCLECHKQMRDYMVLAAHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKV
GYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQPHRPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKT
QVGVFKCPECPLLFVQKPELMQHVKSTHGVPRNVDELSSLQSSADTSSSRPGSRVPTEPPATSVAARSSSLPSGRWGRPEAHRRVEARPR
LRNTGWTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISL
MHGIRNPDLSQTSKVKPPGGHSPQDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQS

--------------------------------------------------------------
>102496_102496_5_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000560079_UBE2L3_chr22_21965145_ENST00000458578_length(transcript)=4486nt_BP=3561nt
CTGGCCTGCAGTCGCCGCCGCCGCCGCCAGGTGGTGTTTGGACTCTAGACCATGTGCCTAGGTAGAAGTTTTTCCTTTCTCCGCAGCTCT
GCTCCCCTAGCAACGCTCGCCACACCCTTGTTTTGAGATCCTCTCTAAGGAGCGGAGAGTTTAATAGGCAAGAAGGAAGGGAGAAGACAG
AAGGAAGACGCTCCCCCGTACGGAGACAGAGGGAGGGGGGGCTCCAAAGCCGAAAGAGGAGGTCCCTACCTGCCACGGATACCAGTCAGC
CCTTGCCAGCATCCAGCCATGGGGGATATGAAAACCCCAGATTTTGATGACCTTCTGGCTGCCTTTGACATCCCAGACCCCACCAGCCTT
GATGCCAAGGAGGCCATCCAGACACCCAGTGAGGAGAATGAGAGTCCCCTCAAACCTCCAGGCATATGTATGGATGAAAGTGTGTCCTTG
TCTCACTCAGGATCAGCCCCCGATGTGCCGGCCGTGAGTGTCATTGTCAAGAACACCAGCCGCCAGGAGTCATTTGAAGCGGAGAAAGAC
CACATTACTCCCAGTCTCCTACACAATGGATTCCGGGGCTCAGATCTGCCTCCAGATCCCCACAACTGTGGGAAATTTGATTCTACTTTT
ATGAATGGAGACAGTGCCAGGAGTTTCCCTGGCAAACTGGAGCCTCCCAAGTCAGAGCCATTACCCACCTTCAACCAGTTCAGTCCAATC
TCCAGCCCAGAACCTGAGGATCCCATCAAAGATAACGGATTTGGGATAAAGCCCAAACACTCTGACAGTTATTTCCCACCCCCTCTTGGG
TGCGGGGCTGTGGGAGGCCCAGTCCTGGAGGCTCTGGCTAAGTTTCCGGTTCCAGAGCTGCATATGTTTGATCATTTTTGTAAGAAAGAA
CCCAAGCCAGAACCCCTGCCCTTGGGGAGCCAGCAGGAACACGAGCAAAGTGGGCAGAACACAGTGGAACCTCACAAGGATCCGGATGCC
ACTCGATTCTTCGGGGAAGCTTTGGAGTTCAACAGCCATCCTAGCAACAGTATTGGAGAGTCCAAGGGGCTTGCCCGGGAGCTTGGTACC
TGCTCATCAGTCCCCCCTAGGCAGCGTCTAAAGCCAGCTCATTCCAAGCTGTCCTCTTGTGTGGCAGCCTTGGTGGCCTTGCAGGCCAAA
AGAGTGGCTAGTGTCACTAAGGAGGATCAGCCTGGCCACACAAAGGATCTCTCAGGGCCCACTAAAGAGAGTTCTAAAGGTAGCCCCAAA
ATGCCCAAGTCACCAAAGAGTCCCCGGAGCCCTCTGGAGGCCACTAGAAAAAGTATCAAGCCATCGGACAGCCCTCGTAGCATCTGCAGT
GACAGCAGCAGCAAAGGCTCACCGTCTGTGGCTGCCAGCTCCCCACCAGCAATTCCCAAAGTGAGAATCAAAACCATTAAGACATCATCA
GGGGAAATCAAACGGACTGTCACAAGGATCCTGCCAGATCCTGATGATCCAAGTAAGTCCCCTGTTGGGTCACCTCTAGGGAGCGCCATT
GCAGAGGCCCCCAGCGAGATGCCAGGGGATGAGGTGCCTGTGGAAGAGCACTTTCCTGAGGCAGGCACAAATTCAGGGAGCCCCCAGGGG
GCCAGGAAAGGGGACGAGAGCATGACAAAGGCCAGTGACTCGTCATCTCCCAGCTGCAGTTCTGGGCCCCGGGTCCCAAAGGGGGCTGCC
CCAGGCTCACAGACAGGCAAGAAGCAACAGAGCACAGCACTGCAGGCATCCACCCTGGCCCCTGCCAACCTCCTGCCCAAAGCCGTGCAC
TTGGCCAACCTGAACCTCGTCCCCCACAGTGTTGCTGCATCAGTGACAGCCAAGTCTTCAGTGCAAAGACGGAGCCAGCCACAGCTTACA
CAAATGTCGGTGCCCCTGGTCCACCAGGTGAAAAAGGCTGCCCCACTGATTGTAGAGGTCTTCAACAAGGTCCTTCACAGCTCCAACCCC
GTGCCCCTCTATGCGCCAAATCTCAGCCCGCCTGCGGACAGCAGGATCCACGTGCCGGCCAGTGGGTACTGCTGCCTGGAGTGTGGAGAC
GCATTTGCCTTAGAGAAGAGCCTGAGCCAGCACTATGGCCGGCGGAGCGTCCACATTGAGGTACTGTGCACACTGTGCTCCAAGACGCTG
CTCTTCTTCAACAAGTGCAGCCTGCTCCGGCACGCCCGTGACCACAAGAGCAAGGGGCTCGTCATGCAGTGTTCCCAGCTGCTGGTGAAG
CCTATCTCTGCGGACCAAATGTTCGTGTCGGCCCCTGTGAACTCCACGGCACCAGCAGCCCCAGCCCCTTCATCCTCTCCCAAACATGGC
CTCACTTCGGGCAGTGCCAGTCCCCCTCCTCCAGCCTTGCCACTCTACCCAGACCCTGTGAGGCTCATCCGGTACTCAATCAAGTGTCTT
GAATGTCACAAGCAGATGCGGGACTACATGGTCCTGGCTGCACATTTCCAGAGGACAACAGAGGAGACAGAGGGGCTGACCTGCCAGGTA
TGCCAAATGCTGCTGCCCAACCAGTGCAGTTTCTGTGCCCACCAGCGGATTCATGCACACAAGTCCCCCTACTGCTGCCCGGAGTGTGGG
GTCCTCTGCCGCTCTGCCTACTTCCAGACCCATGTAAAGGAGAATTGCCTGCACTATGCCCGCAAGGTGGGCTACAGGTGCATCCACTGT
GGTGTCGTCCACCTGACCTTGGCCTTGCTGAAAAGCCACATCCAGGAGCGACACTGCCAGGTTTTCCACAAATGTGCATTCTGCCCCATG
GCCTTCAAGACTGCCAGCAGCACTGCAGACCACAGTGCCACCCAGCACCCCACCCAGCCCCACAGACCCTCCCAGCTCATTTATAAGTGC
TCCTGTGAAATGGTCTTCAACAAGAAGAGGCACATTCAGCAGCATTTTTACCAGAATGTCAGCAAGACGCAGGTGGGCGTCTTCAAGTGC
CCTGAGTGCCCACTCTTGTTCGTGCAGAAGCCGGAGTTGATGCAACACGTCAAGAGCACCCACGGTGTTCCCCGAAATGTGGACGAGCTG
TCAAGCCTCCAGTCTTCAGCGGACACATCCTCAAGCCGCCCTGGCTCTCGAGTTCCCACTGAGCCACCAGCCACTAGTGTGGCTGCTCGG
AGCAGCTCCCTGCCTTCTGGCCGCTGGGGTAGGCCTGAAGCCCACCGCAGGGTGGAAGCCAGGCCGCGGCTGAGGAACACTGGCTGGACC
TGCCAGGAGTGCCAGGAGTGGGTTCCAGATCGGGAGAGCTACGTGTCCCACATGAAAAAGAGCCACGGTCGGACATTGAAGCGGTACCCA
TGCCGGCAGTGTGAACAGTCCTTCCACACCCCCAACAGCCTGCGCAAACACATCCGCAACAACCATGACACAGTAAAGAAGTTCTACACC
TGCGGGTACTGCACAGAGGACAGCCCCAGCTTTCCTCGGCCCTCCCTTCTGGAGAGCCACATCAGCCTTATGCATGGCATCAGAAACCCT
GATTTGAGCCAGACGTCCAAAGTGAAACCTCCGGGTGGACATTCCCCTCAGGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAA
ATCAACTTTCCAGCAGAGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAG
GTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGTAATCCAGTCCCTCATAGCACTGGTGAATGAC
CCCCAGCCTGAGCACCCGCTTCGGGCTGACCTAGCTGAAGAATACTCTAAGGACCGTAAAAAATTCTGTAAGAATGCTGAAGAGTTTACA
AAGAAATATGGGGAAAAGCGACCTGTGGACTAAAATCTGCCACGATTGGTTCCAGCAAGTGTGAGCAGAGACCCCGTGCAGTGCATTCAG
ACACCCCGCAAAGCAGGACTCTGTGGAAATTGACACGTGCCACCGCCTGGCGTTCGCTTGTGGCAGTTACTAACTTTCTACAGTTTTCTT
AATCAAAAGTGGTCTAGGTAACCTGTAAAGAAAGGATTAAAAATTTAAGATGTTCTAGTTCTGCTCTCTTTGTTTTAAAAATCACTGCTT
CAATCTACTTCAAAAGAATGGTGTTTCTTTTCTTGTCCAATTTTATCCAAAATCTTCAAGTTACATTTAACCCATAAGGTTTAAAAAAAA
GGAAAAAAAACGGTTGTGGTTCCCTTTCTTCCCTACCCTTGCCACTCCCACTTTCTGGCACCGAGTTTATTTTTCACTTACTTACTTCCC
CAGACCCCGGGCTCGCCTCCACAAAGGAGAAAAGACTGCCCTGGCGGTCCTGGTGGCTTTTCTTAGCATGTGTGGCACTGTTGCCCAGTG

>102496_102496_5_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000560079_UBE2L3_chr22_21965145_ENST00000458578_length(amino acids)=1217AA_BP=1101
MPRIPVSPCQHPAMGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKPPGICMDESVSLSHSGSAPDVPAVSVIVKNTSRQE
SFEAEKDHITPSLLHNGFRGSDLPPDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIKPKHSDS
YFPPPLGCGAVGGPVLEALAKFPVPELHMFDHFCKKEPKPEPLPLGSQQEHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKG
LARELGTCSSVPPRQRLKPAHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPLEATRKSIKPSD
SPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGT
NSGSPQGARKGDESMTKASDSSSPSCSSGPRVPKGAAPGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPHSVAASVTAKSSVQR
RSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLC
TLCSKTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSPKHGLTSGSASPPPPALPLYPDPVRLI
RYSIKCLECHKQMRDYMVLAAHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKV
GYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQPHRPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKT
QVGVFKCPECPLLFVQKPELMQHVKSTHGVPRNVDELSSLQSSADTSSSRPGSRVPTEPPATSVAARSSSLPSGRWGRPEAHRRVEARPR
LRNTGWTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISL
MHGIRNPDLSQTSKVKPPGGHSPQDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQS

--------------------------------------------------------------
>102496_102496_6_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000560079_UBE2L3_chr22_21965145_ENST00000545681_length(transcript)=4583nt_BP=3561nt
CTGGCCTGCAGTCGCCGCCGCCGCCGCCAGGTGGTGTTTGGACTCTAGACCATGTGCCTAGGTAGAAGTTTTTCCTTTCTCCGCAGCTCT
GCTCCCCTAGCAACGCTCGCCACACCCTTGTTTTGAGATCCTCTCTAAGGAGCGGAGAGTTTAATAGGCAAGAAGGAAGGGAGAAGACAG
AAGGAAGACGCTCCCCCGTACGGAGACAGAGGGAGGGGGGGCTCCAAAGCCGAAAGAGGAGGTCCCTACCTGCCACGGATACCAGTCAGC
CCTTGCCAGCATCCAGCCATGGGGGATATGAAAACCCCAGATTTTGATGACCTTCTGGCTGCCTTTGACATCCCAGACCCCACCAGCCTT
GATGCCAAGGAGGCCATCCAGACACCCAGTGAGGAGAATGAGAGTCCCCTCAAACCTCCAGGCATATGTATGGATGAAAGTGTGTCCTTG
TCTCACTCAGGATCAGCCCCCGATGTGCCGGCCGTGAGTGTCATTGTCAAGAACACCAGCCGCCAGGAGTCATTTGAAGCGGAGAAAGAC
CACATTACTCCCAGTCTCCTACACAATGGATTCCGGGGCTCAGATCTGCCTCCAGATCCCCACAACTGTGGGAAATTTGATTCTACTTTT
ATGAATGGAGACAGTGCCAGGAGTTTCCCTGGCAAACTGGAGCCTCCCAAGTCAGAGCCATTACCCACCTTCAACCAGTTCAGTCCAATC
TCCAGCCCAGAACCTGAGGATCCCATCAAAGATAACGGATTTGGGATAAAGCCCAAACACTCTGACAGTTATTTCCCACCCCCTCTTGGG
TGCGGGGCTGTGGGAGGCCCAGTCCTGGAGGCTCTGGCTAAGTTTCCGGTTCCAGAGCTGCATATGTTTGATCATTTTTGTAAGAAAGAA
CCCAAGCCAGAACCCCTGCCCTTGGGGAGCCAGCAGGAACACGAGCAAAGTGGGCAGAACACAGTGGAACCTCACAAGGATCCGGATGCC
ACTCGATTCTTCGGGGAAGCTTTGGAGTTCAACAGCCATCCTAGCAACAGTATTGGAGAGTCCAAGGGGCTTGCCCGGGAGCTTGGTACC
TGCTCATCAGTCCCCCCTAGGCAGCGTCTAAAGCCAGCTCATTCCAAGCTGTCCTCTTGTGTGGCAGCCTTGGTGGCCTTGCAGGCCAAA
AGAGTGGCTAGTGTCACTAAGGAGGATCAGCCTGGCCACACAAAGGATCTCTCAGGGCCCACTAAAGAGAGTTCTAAAGGTAGCCCCAAA
ATGCCCAAGTCACCAAAGAGTCCCCGGAGCCCTCTGGAGGCCACTAGAAAAAGTATCAAGCCATCGGACAGCCCTCGTAGCATCTGCAGT
GACAGCAGCAGCAAAGGCTCACCGTCTGTGGCTGCCAGCTCCCCACCAGCAATTCCCAAAGTGAGAATCAAAACCATTAAGACATCATCA
GGGGAAATCAAACGGACTGTCACAAGGATCCTGCCAGATCCTGATGATCCAAGTAAGTCCCCTGTTGGGTCACCTCTAGGGAGCGCCATT
GCAGAGGCCCCCAGCGAGATGCCAGGGGATGAGGTGCCTGTGGAAGAGCACTTTCCTGAGGCAGGCACAAATTCAGGGAGCCCCCAGGGG
GCCAGGAAAGGGGACGAGAGCATGACAAAGGCCAGTGACTCGTCATCTCCCAGCTGCAGTTCTGGGCCCCGGGTCCCAAAGGGGGCTGCC
CCAGGCTCACAGACAGGCAAGAAGCAACAGAGCACAGCACTGCAGGCATCCACCCTGGCCCCTGCCAACCTCCTGCCCAAAGCCGTGCAC
TTGGCCAACCTGAACCTCGTCCCCCACAGTGTTGCTGCATCAGTGACAGCCAAGTCTTCAGTGCAAAGACGGAGCCAGCCACAGCTTACA
CAAATGTCGGTGCCCCTGGTCCACCAGGTGAAAAAGGCTGCCCCACTGATTGTAGAGGTCTTCAACAAGGTCCTTCACAGCTCCAACCCC
GTGCCCCTCTATGCGCCAAATCTCAGCCCGCCTGCGGACAGCAGGATCCACGTGCCGGCCAGTGGGTACTGCTGCCTGGAGTGTGGAGAC
GCATTTGCCTTAGAGAAGAGCCTGAGCCAGCACTATGGCCGGCGGAGCGTCCACATTGAGGTACTGTGCACACTGTGCTCCAAGACGCTG
CTCTTCTTCAACAAGTGCAGCCTGCTCCGGCACGCCCGTGACCACAAGAGCAAGGGGCTCGTCATGCAGTGTTCCCAGCTGCTGGTGAAG
CCTATCTCTGCGGACCAAATGTTCGTGTCGGCCCCTGTGAACTCCACGGCACCAGCAGCCCCAGCCCCTTCATCCTCTCCCAAACATGGC
CTCACTTCGGGCAGTGCCAGTCCCCCTCCTCCAGCCTTGCCACTCTACCCAGACCCTGTGAGGCTCATCCGGTACTCAATCAAGTGTCTT
GAATGTCACAAGCAGATGCGGGACTACATGGTCCTGGCTGCACATTTCCAGAGGACAACAGAGGAGACAGAGGGGCTGACCTGCCAGGTA
TGCCAAATGCTGCTGCCCAACCAGTGCAGTTTCTGTGCCCACCAGCGGATTCATGCACACAAGTCCCCCTACTGCTGCCCGGAGTGTGGG
GTCCTCTGCCGCTCTGCCTACTTCCAGACCCATGTAAAGGAGAATTGCCTGCACTATGCCCGCAAGGTGGGCTACAGGTGCATCCACTGT
GGTGTCGTCCACCTGACCTTGGCCTTGCTGAAAAGCCACATCCAGGAGCGACACTGCCAGGTTTTCCACAAATGTGCATTCTGCCCCATG
GCCTTCAAGACTGCCAGCAGCACTGCAGACCACAGTGCCACCCAGCACCCCACCCAGCCCCACAGACCCTCCCAGCTCATTTATAAGTGC
TCCTGTGAAATGGTCTTCAACAAGAAGAGGCACATTCAGCAGCATTTTTACCAGAATGTCAGCAAGACGCAGGTGGGCGTCTTCAAGTGC
CCTGAGTGCCCACTCTTGTTCGTGCAGAAGCCGGAGTTGATGCAACACGTCAAGAGCACCCACGGTGTTCCCCGAAATGTGGACGAGCTG
TCAAGCCTCCAGTCTTCAGCGGACACATCCTCAAGCCGCCCTGGCTCTCGAGTTCCCACTGAGCCACCAGCCACTAGTGTGGCTGCTCGG
AGCAGCTCCCTGCCTTCTGGCCGCTGGGGTAGGCCTGAAGCCCACCGCAGGGTGGAAGCCAGGCCGCGGCTGAGGAACACTGGCTGGACC
TGCCAGGAGTGCCAGGAGTGGGTTCCAGATCGGGAGAGCTACGTGTCCCACATGAAAAAGAGCCACGGTCGGACATTGAAGCGGTACCCA
TGCCGGCAGTGTGAACAGTCCTTCCACACCCCCAACAGCCTGCGCAAACACATCCGCAACAACCATGACACAGTAAAGAAGTTCTACACC
TGCGGGTACTGCACAGAGGACAGCCCCAGCTTTCCTCGGCCCTCCCTTCTGGAGAGCCACATCAGCCTTATGCATGGCATCAGAAACCCT
GATTTGAGCCAGACGTCCAAAGTGAAACCTCCGGGTGGACATTCCCCTCAGGACAACCCTCCATATGATAAGGGAGCCTTCAGAATCGAA
ATCAACTTTCCAGCAGAGTACCCATTCAAACCACCGAAGATCACATTTAAAACAAAGATCTATCACCCAAACATCGACGAAAAGGGGCAG
GTCTGTCTGCCAGTAATTAGTGCCGAAAACTGGAAGCCAGCAACCAAAACCGACCAAGTAATCCAGTCCCTCATAGCACTGGTGAATGAC
CCCCAGCCTGAGCACCCGCTTCGGGCTGACCTAGCTGAAGAATACTCTAAGGACCGTAAAAAATTCTGTAAGAATGCTGAAGAGTTTACA
AAGAAATATGGGGAAAAGCGACCTGTGGACTAAAATCTGCCACGATTGGTTCCAGCAAGTGTGAGCAGAGACCCCGTGCAGTGCATTCAG
ACACCCCGCAAAGCAGGACTCTGTGGAAATTGACACGTGCCACCGCCTGGCGTTCGCTTGTGGCAGTTACTAACTTTCTACAGTTTTCTT
AATCAAAAGTGGTCTAGGTAACCTGTAAAGAAAGGATTAAAAATTTAAGATGTTCTAGTTCTGCTCTCTTTGTTTTAAAAATCACTGCTT
CAATCTACTTCAAAAGAATGGTGTTTCTTTTCTTGTCCAATTTTATCCAAAATCTTCAAGTTACATTTAACCCATAAGGTTTAAAAAAAA
GGAAAAAAAACGGTTGTGGTTCCCTTTCTTCCCTACCCTTGCCACTCCCACTTTCTGGCACCGAGTTTATTTTTCACTTACTTACTTCCC
CAGACCCCGGGCTCGCCTCCACAAAGGAGAAAAGACTGCCCTGGCGGTCCTGGTGGCTTTTCTTAGCATGTGTGGCACTGTTGCCCAGTG
TGGGAGTTGGTTTAAATTCTCCTGACTCCAGTTTATAACATCCTTTTAAAAAATTTAAAAACAAACAGCCACACCCCTCCTCCAGTCCTT

>102496_102496_6_ZNF592-UBE2L3_ZNF592_chr15_85343208_ENST00000560079_UBE2L3_chr22_21965145_ENST00000545681_length(amino acids)=1217AA_BP=1101
MPRIPVSPCQHPAMGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKPPGICMDESVSLSHSGSAPDVPAVSVIVKNTSRQE
SFEAEKDHITPSLLHNGFRGSDLPPDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIKPKHSDS
YFPPPLGCGAVGGPVLEALAKFPVPELHMFDHFCKKEPKPEPLPLGSQQEHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKG
LARELGTCSSVPPRQRLKPAHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPLEATRKSIKPSD
SPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGT
NSGSPQGARKGDESMTKASDSSSPSCSSGPRVPKGAAPGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPHSVAASVTAKSSVQR
RSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLC
TLCSKTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSPKHGLTSGSASPPPPALPLYPDPVRLI
RYSIKCLECHKQMRDYMVLAAHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKV
GYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQPHRPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKT
QVGVFKCPECPLLFVQKPELMQHVKSTHGVPRNVDELSSLQSSADTSSSRPGSRVPTEPPATSVAARSSSLPSGRWGRPEAHRRVEARPR
LRNTGWTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISL
MHGIRNPDLSQTSKVKPPGGHSPQDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNF592-UBE2L3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF592-UBE2L3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF592-UBE2L3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource