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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF618-MTAP (FusionGDB2 ID:102570)

Fusion Gene Summary for ZNF618-MTAP

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF618-MTAP
Fusion gene ID: 102570
HgeneTgene
Gene symbol

ZNF618

MTAP

Gene ID

114991

4507

Gene namezinc finger protein 618methylthioadenosine phosphorylase
SynonymsFP13169|NEDD10BDMF|DMSFH|DMSMFH|HEL-249|LGMBF|MSAP|c86fus
Cytomap

9q32

9p21.3

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 618neural precursor cell expressed, developmentally down-regulated 10S-methyl-5'-thioadenosine phosphorylase5'-methylthioadenosine phosphorylaseMTA phosphorylaseMTAPaseMeSAdo phosphorylaseepididymis luminal protein 249epididymis secretory sperm binding protein
Modification date2020031320200313
UniProtAcc.

Q13126

Ensembl transtripts involved in fusion geneENST00000288466, ENST00000374126, 
ENST00000470105, 		ENST00000427788, 
ENST00000380172, ENST00000460874, 
ENST00000580900, 
Fusion gene scores* DoF score7 X 4 X 6=1685 X 5 X 4=100
# samples 86
** MAII scorelog2(8/168*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/100*10)=-0.736965594166206
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF618 [Title/Abstract] AND MTAP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF618(116638693)-MTAP(21815432), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMTAP

GO:0006738

nicotinamide riboside catabolic process

19001417


check buttonFusion gene breakpoints across ZNF618 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MTAP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-EJ-A8FO-01AZNF618chr9

116638693

-MTAPchr9

21815432

+
ChimerDB4PRADTCGA-EJ-A8FO-01AZNF618chr9

116638693

+MTAPchr9

21815432

+


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Fusion Gene ORF analysis for ZNF618-MTAP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000288466ENST00000427788ZNF618chr9

116638693

+MTAPchr9

21815432

+
5CDS-3UTRENST00000374126ENST00000427788ZNF618chr9

116638693

+MTAPchr9

21815432

+
In-frameENST00000288466ENST00000380172ZNF618chr9

116638693

+MTAPchr9

21815432

+
In-frameENST00000288466ENST00000460874ZNF618chr9

116638693

+MTAPchr9

21815432

+
In-frameENST00000288466ENST00000580900ZNF618chr9

116638693

+MTAPchr9

21815432

+
In-frameENST00000374126ENST00000380172ZNF618chr9

116638693

+MTAPchr9

21815432

+
In-frameENST00000374126ENST00000460874ZNF618chr9

116638693

+MTAPchr9

21815432

+
In-frameENST00000374126ENST00000580900ZNF618chr9

116638693

+MTAPchr9

21815432

+
intron-3CDSENST00000470105ENST00000380172ZNF618chr9

116638693

+MTAPchr9

21815432

+
intron-3CDSENST00000470105ENST00000460874ZNF618chr9

116638693

+MTAPchr9

21815432

+
intron-3CDSENST00000470105ENST00000580900ZNF618chr9

116638693

+MTAPchr9

21815432

+
intron-3UTRENST00000470105ENST00000427788ZNF618chr9

116638693

+MTAPchr9

21815432

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000374126ZNF618chr9116638693+ENST00000580900MTAPchr921815432+1552132991103334
ENST00000374126ZNF618chr9116638693+ENST00000380172MTAPchr921815432+601513299950283
ENST00000374126ZNF618chr9116638693+ENST00000460874MTAPchr921815432+125713299950283
ENST00000288466ZNF618chr9116638693+ENST00000580900MTAPchr921815432+1552132991103334
ENST00000288466ZNF618chr9116638693+ENST00000380172MTAPchr921815432+601513299950283
ENST00000288466ZNF618chr9116638693+ENST00000460874MTAPchr921815432+125713299950283

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000374126ENST00000580900ZNF618chr9116638693+MTAPchr921815432+0.0042142510.9957858
ENST00000374126ENST00000380172ZNF618chr9116638693+MTAPchr921815432+0.0004284140.9995716
ENST00000374126ENST00000460874ZNF618chr9116638693+MTAPchr921815432+0.0016417180.9983583
ENST00000288466ENST00000580900ZNF618chr9116638693+MTAPchr921815432+0.0042142510.9957858
ENST00000288466ENST00000380172ZNF618chr9116638693+MTAPchr921815432+0.0004284140.9995716
ENST00000288466ENST00000460874ZNF618chr9116638693+MTAPchr921815432+0.0016417180.9983583

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Fusion Genomic Features for ZNF618-MTAP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNF618chr9116638693+MTAPchr921815431+2.48E-111
ZNF618chr9116638693+MTAPchr921815431+2.48E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZNF618-MTAP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:116638693/chr9:21815432)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MTAP

Q13126

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. {ECO:0000255|HAMAP-Rule:MF_03155, ECO:0000269|PubMed:3091600}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMTAPchr9:116638693chr9:21815432ENST0000038017208220_22211284.0RegionNote=Substrate binding
TgeneMTAPchr9:116638693chr9:21815432ENST000003801720860_6111284.0RegionNote=Phosphate binding
TgeneMTAPchr9:116638693chr9:21815432ENST000003801720893_9411284.0RegionNote=Phosphate binding
TgeneMTAPchr9:116638693chr9:21815432ENST0000058090008220_22211335.0RegionNote=Substrate binding
TgeneMTAPchr9:116638693chr9:21815432ENST000005809000860_6111335.0RegionNote=Phosphate binding
TgeneMTAPchr9:116638693chr9:21815432ENST000005809000893_9411335.0RegionNote=Phosphate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF618chr9:116638693chr9:21815432ENST00000288466+114147_16911862.0Zinc fingerC2H2-type 1
HgeneZNF618chr9:116638693chr9:21815432ENST00000288466+114188_21011862.0Zinc fingerC2H2-type 2
HgeneZNF618chr9:116638693chr9:21815432ENST00000288466+114256_27811862.0Zinc fingerC2H2-type 3
HgeneZNF618chr9:116638693chr9:21815432ENST00000288466+114392_41411862.0Zinc fingerC2H2-type 4
HgeneZNF618chr9:116638693chr9:21815432ENST00000374126+115147_16911955.0Zinc fingerC2H2-type 1
HgeneZNF618chr9:116638693chr9:21815432ENST00000374126+115188_21011955.0Zinc fingerC2H2-type 2
HgeneZNF618chr9:116638693chr9:21815432ENST00000374126+115256_27811955.0Zinc fingerC2H2-type 3
HgeneZNF618chr9:116638693chr9:21815432ENST00000374126+115392_41411955.0Zinc fingerC2H2-type 4


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Fusion Gene Sequence for ZNF618-MTAP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102570_102570_1_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000288466_MTAP_chr9_21815432_ENST00000380172_length(transcript)=6015nt_BP=132nt
GGCGGCGGCGGCGGCGGCGGCGGCGGCATTGTGCGCGCACCAGCAGCCCGGCCCGGGAGGAGCAGGACGCGCCGGGGCCGCCTCCTCCCG
CACGGACCCATGAACCAGCCGGGCGGCGCGGCGGCTCCGCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAA
GGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTC
CTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACA
CATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACC
ACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAA
ACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTT
AGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAG
GCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTA
AAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTC
CATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAAT
TCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTG
TAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACA
TGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAACCCACCATTCTCTTCTCCCCCTATTAAATTTGCAACAATAAAGGGTGGAGG
GTAATCTCTACTTTCCTATACTGCCAAAGAATGTGAGGAAGAAATGGGACTCTTTGGTTATTTATTGATGCGACTGTAAATTGGTACAGT
ATTTCTGGAGGGCAATTTGGTAAAATGCATCAAAAGACTTAAAAATACGGACGTACTTTGTGCTGGGAACTCTACATCTAGCAATTTCTC
TTTAAAACCATATCAGAGATGCATACAAAGAATTATATATAAAGAAGGGTGTTTAATAATGATAGTTATAATAATAAATAATTGAAACAA
TCTGAATCCCTTGCAATTGGAGGTAAATTATGTCTTAGTTATAATTAGATTGTGAATCAGCCAACTGAAAATCCTTTTTGCATATTTCAA
TGTCCTAAAAAGACACGGTTGCTCTATATATGAAGTGAAAAAAGGATATGGTAGCATTTTATAGTACTAGTTTTGCTTTAAAATGCTATG
TAAATATACAAAAAAACTAGAAAGAAATATATATAACCTTGTTATTGTATTTGGGGGAGGGATACTGGGATAATTTTTATTTTCTTTGAA
TCTTTCTGTGTCTTCACATTTTTCTACAGTGAATTTAATCAAATAGTAAAGTTGTTGTAAAAATAAAAGTGGATTTAGAAAGATCCAGTT
CTTGAAAACACTGTTTCTGGTAATGAAGCAGAATTTAAGTTGGTAATATTAAGGTGAATGTCATTTAAGGGAGTTACATCTTTATTCTGC
TAAAGAAGAGGATCATTGATTTCTGTACAGTCAGAACAGTACTTGGGTTTGCAACAGCTTTCTGAGAAAAGCTAGGTGTTTAATAGTTTA
ACTGAAAGTTTAACTATTTAAAAGACTAAATGCACATTTTATGGTATCTGATATTTTAAAAAGTAATGTTTGATTCTCCTTTTTATGAGT
TAAATTATTTTATACGAGTTGGTAATTTTTGCTTTTTAATAAAGTGGAAGCTTGCTTTTTTAACTCTTTTTTTATTGTTATTTTATAGAA
ATGCTTTTTGTTGGCCGGGCACAGTTGCTCATCCATGTAATCCCAGCACTGTGGGAGGCCGAGACGGGTGGATCACAAGGTCAGGAGATC
GAGACCATCCTGGCTAATGCGTTGAAACTCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCACCTGTAGTCCCAG
CTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCAGAGCTTGCAGTGAGACGAGCTTGTGCCA
CTGCACTCCAGCCTGGGCAACAGAGTAAGACTCAGTCTCAAAAAAAAAAAAAAGAGTGAAATGCTTTTTGTTTGCTTCAGTTTTTTATCA
TGGGGAGATCTTTTTCCTCAGAATTGTTTTCTTTTCACTGTAGGCTATTACAGGATACTTCAGGATCAAGATACAGAACCTTTTATTTAA
AGAGTTTGTAAAGTCAATGTGTTTGTTTGTGTCTCTGAGATTGACTTCAAGATAATAAGCTGCTAATTGTAAACAAAACAGTTACCCTCC
AGTATTAATATGACTCATTAGTGTGAGCCATTTGGGTCAAGTATGATTATGACCCTTGGACTTCCTGATGTAGTATTAAATTTCAACTCT
GGTTATCCATTAGCAATCTGTAGAGAACTTAATGAACCTGAACCCAGGCTTCTCTAGCTCTGGTAACGTGTGATTGTTTTCACTACAATA
TGATACATAGATGGTACCTTACTTTTCCTCATTCTTAATAGGTGTCTAAGAATGTCAGGGCAAAAGTATGGGCATTTTTCTTGCTATGTT
CAGAAAGTACAGTTCTCTCCAACTTGCAGAGGTACTTTTCTTGATTAAATAGCCTTCTCTAGCAACATCATTTTCAGACTAACTAAATGA
ATGCAGTATACTCTTTTCTTTGTTCTCAATCATTCACTCCTTATGCAAAGCCAATATAATTTTCCTCATACCTTATGCTTGAGGATATTG
TTGAAGAACACTTCCTGGAACACTTCTCACTTGTGATGCTGTACTAATTTTTTTTTTTTAATTTAAGCTAGTATACTAAGTGAACACCAT
GGTCAGTTGTGAGCATTTTGGTTTCCGCAAAGGATGGATGGTGAGCATCATGGGAAAGCTGTAGTTTAGTGACTTAGCCCTTAGTGATTA
ATAGATTTGCATGTACATAGAAGTCTTTGTTGGCCTTATAATCTGCTGTTATATTTGGCATGGATTTTCATGGTTTTGAGAATGACATCC
TGGCCCTGTGGTCCCCGAGGGTCATGGTCCTTGTGACCTGGCCCCTGTTCACTGCCCCCTTCGCTAGCACGAGTTGCTGTGCAGGGCTGG
AGGTAGCTACCATGGCTTGTTTCAAGGAAGGAAACTCTGGTACGGTGGCACCCTCAGGAGTGGAGGACAGTGAACTTCCTTGAAGAGGGA
GTGACTAAGGTGACCTCCAACCTGCCCTGAGCCAGCTGCCCTGCAGGTGCCACGTGAGCCTGCTCTGGCATCCACAGGATGCTCCTGGAG
CCTCTTCTCTGGCTGCTACCTCAGGGCATGGTTGTGGCCCCACCAACACCTATTTTCCAAATAATTATTCATTCTTGTGACAGTGGCCTG
AACATGTTTTTAATTTTCTCAACAAGCATTTAGCCAGCACTTATCCAGTGAAACAATTTGATAAGGTTTCAAGGAGTATCTGATGGGTTA
GGAAGTCACGAAATGAGGAGTTCTTGCCACATTTGCAGAGTCCCTCCTTGATAAGGTTTGGCGGTGTCCCCACCCAAATCTCATGTTGAA
TTGTAGTTCCCATAATCCCCACATGTTGTGGGAGGGACCCAGTGGGAGGTAATTAAATCATGGGGGTGGTTACCCCCACACTGCTGTTCT
CATGATACTGAGTTCTCACAAGTCCTGTTTGTTTTATAAGGGGCTTTTCCCCCTTTTGCTCAACACTTCTTCCTGCCATCATGTGAAGAA
GGACGTGTTTGTTTCCCCTTCTGCCACGATTGTAAGTTTCCTGAGGCCTTCCCAGCTATGTGGAACTGTGAGTTAATTAAACCTCTTTCC
TTTATAAATTACCCAGTCATGGGCAGTCCTTTACAGCAGCATGAGAATGGACTAATACACTCCTCAAATGTTTTGAAGATTGTTGCACCT
TGGAACTACCAGTGTGCACACAATCTGGCTCAATGTATATATTGGCCCAGCAAGGCAAAGAACTGAAGTTCCAGGATGGAAGAACCTGTG
TTCTCCTCATAATAGTATAGAATAATTCAAGATAGGCAAGAAGGACAGCAGTAAATGAAGACCATGGAAGAAAAGAAGGAATGCCAAAGA
TCGAGGAAATCTACCAAGACTAGTAGGGTAGTCCAGAAGAAGCTGTTTCAGGGCCTGTTGCCAGCTATGCCTTTGAGAACCTCGGGATCC
CAAAGAATGAGGGGAATTTCTTCAGAAAGACAATCTCGGCATGCATTATTTCTTTGTTTTGAAGATTCACTCATGTTGCATGCATCTGTA
GCTTGTGCCTTTTTTATTGCCTAGTAGTATTCTGTCATATGCCTATCTTACAATTTGATTATCTATTCACCTGTTGATGAATGTTTGAAT
TTTTTCCATTTGAGGAATTTTATGAATAAAGCTGCTATAAGCATGAAATTACAAGTCTTTTTGTGAACATATTTTCACTTGTGCAAATGC
CTATACTCCCACCAGTAATTTGTAAGAATTCTTGACAAAGCTTGGTATTGTCAGCGTTTTTAATTTTAGCCATTCTATTGGGTATATTTT
GATATCTCGTGGTTTTGATTTGCATTTTTCTGATTAAAGATGTTGAACTTCTTTTCATGTGCTTATTGGCCATTCACATATTTCGTGAAC
TATCTGTACAAATATTTTTGTTTATTAAAAAATTAGATTGTTTTGTTTTATTATTGAATAGTAAGAATTGTTTATATATTCTGGATACAC
TCTTTTTCAGATATGTGTGTTGTGACTATTCTTAGTCTTTAGCTTGCCTTTTCATTTTCTTAATTATGTCTTTCAAAGAACAAGTTTTTC
ATTTTGACGAAGCCTAGTTTATCAATTTTTTTTATGGTTGGTGCTTTTTGTGTGTTCCAAGAAATCTTTGCCTACTCATTTAATTACCTG
TGTGCCCTTGTCAAAATCATTTAATTTTGACTACTCACTTAATTACCTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATTTA
CTGTTTATCTGTGAATCTGGATGATCTATTTATGTCATTTATCTATGTGTCTCTTCTTATGCCAGTACCCCACTGTCTTGATTATTGTGG
CTTTATGGTGTCTTGAAATTAAGTATTGTTAAGCTTTGCAATCTTTTCCAAGATTGTTTTGGCTATAGGTCCTTTCTTTATAAAGTTTAT
ATTAAGCTTCTCCATTTTTCTTTAAGAAAAAATCTGCTGGAATGGCACTGAATTTTTAGGTCGATTTGGGAAGAATTGACAATATTGAAC
CTTTCAATCGATGGACATGGTATGTTTCTGCATTTATTTGGGCCTTTTAAAATTTATCTCAGCAATATTTTGTAGTTTTAGTGAAGAAGT
CTTGTATATATCTTTTGTTAAATGTATTCCTAAATATTTTGTGGAAATGTTACTGTAAATAGTACTTTAATTTCATTTTTAAGTTTATTG

>102570_102570_1_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000288466_MTAP_chr9_21815432_ENST00000380172_length(amino acids)=283AA_BP=11
MNQPGGAAAPQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVI
VTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSR
AESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNL

--------------------------------------------------------------
>102570_102570_2_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000288466_MTAP_chr9_21815432_ENST00000460874_length(transcript)=1257nt_BP=132nt
GGCGGCGGCGGCGGCGGCGGCGGCGGCATTGTGCGCGCACCAGCAGCCCGGCCCGGGAGGAGCAGGACGCGCCGGGGCCGCCTCCTCCCG
CACGGACCCATGAACCAGCCGGGCGGCGCGGCGGCTCCGCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAA
GGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTC
CTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACA
CATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACC
ACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAA
ACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTT
AGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAG
GCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTA
AAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTC
CATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAAT
TCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTG
TAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACA

>102570_102570_2_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000288466_MTAP_chr9_21815432_ENST00000460874_length(amino acids)=283AA_BP=11
MNQPGGAAAPQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVI
VTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSR
AESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNL

--------------------------------------------------------------
>102570_102570_3_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000288466_MTAP_chr9_21815432_ENST00000580900_length(transcript)=1552nt_BP=132nt
GGCGGCGGCGGCGGCGGCGGCGGCGGCATTGTGCGCGCACCAGCAGCCCGGCCCGGGAGGAGCAGGACGCGCCGGGGCCGCCTCCTCCCG
CACGGACCCATGAACCAGCCGGGCGGCGCGGCGGCTCCGCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAA
GGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTC
CTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACA
CATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACC
ACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAA
ACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTT
AGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAG
GCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTA
AAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTC
CATAACCTGAAGATGATCAAGTTCCAGATGATCCTCAGTGAGGGATACCATCCTTTCAATATTCAAGAGTCACCCTTCTACAGAGGACTC
CTAGACTTCCCATCAGTGGGACATGGCAGAGGTGAAATCCTGCCCCTGTCTCCCTTAGACCTGGCTGGATACTGCTTCCAACAACCCATG
CAGCCACCCTGCCCTGACAGCTAGCAAGAGGCCAAGACCCACAGAACAATCACCATCACACCTCTGTCAGCAGGAAGCAGTTACAGAAGA
CTGACCTTCATCCAGTTTCCCAAAGAATTGGGTCATGGATTTTTGCGGGGGAAAATGTTAGAGTAGGTAATTAGGCAGACATGAGTAAGG
GAGGAGAGACCCCCTCCAACTAGGAATGTCAGGTGAGCATCAGATGATCATCAGGTGGTTGTTAAACTCTCTCTCTAAAATAATAATAGG
TTGCAACTGGCAGCAGGGAAAGACAATCTCCCAATAGATAGAAAAGTCCTGAAGCTGGTGATCAGCAGCTTCCTAGTAAGATCTCAGGAT
TTGGGCAAGCAGGCTCAAACATGGGCACTAAGAGGCAAAATCGTGGAGTTTAACTGGTATACAGACTTCCTCTAAAAACACATGACTCAT

>102570_102570_3_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000288466_MTAP_chr9_21815432_ENST00000580900_length(amino acids)=334AA_BP=11
MNQPGGAAAPQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVI
VTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSR
AESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNL

--------------------------------------------------------------
>102570_102570_4_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000374126_MTAP_chr9_21815432_ENST00000380172_length(transcript)=6015nt_BP=132nt
GGCGGCGGCGGCGGCGGCGGCGGCGGCATTGTGCGCGCACCAGCAGCCCGGCCCGGGAGGAGCAGGACGCGCCGGGGCCGCCTCCTCCCG
CACGGACCCATGAACCAGCCGGGCGGCGCGGCGGCTCCGCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAA
GGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTC
CTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACA
CATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACC
ACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAA
ACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTT
AGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAG
GCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTA
AAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTC
CATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAAT
TCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTG
TAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACA
TGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAACCCACCATTCTCTTCTCCCCCTATTAAATTTGCAACAATAAAGGGTGGAGG
GTAATCTCTACTTTCCTATACTGCCAAAGAATGTGAGGAAGAAATGGGACTCTTTGGTTATTTATTGATGCGACTGTAAATTGGTACAGT
ATTTCTGGAGGGCAATTTGGTAAAATGCATCAAAAGACTTAAAAATACGGACGTACTTTGTGCTGGGAACTCTACATCTAGCAATTTCTC
TTTAAAACCATATCAGAGATGCATACAAAGAATTATATATAAAGAAGGGTGTTTAATAATGATAGTTATAATAATAAATAATTGAAACAA
TCTGAATCCCTTGCAATTGGAGGTAAATTATGTCTTAGTTATAATTAGATTGTGAATCAGCCAACTGAAAATCCTTTTTGCATATTTCAA
TGTCCTAAAAAGACACGGTTGCTCTATATATGAAGTGAAAAAAGGATATGGTAGCATTTTATAGTACTAGTTTTGCTTTAAAATGCTATG
TAAATATACAAAAAAACTAGAAAGAAATATATATAACCTTGTTATTGTATTTGGGGGAGGGATACTGGGATAATTTTTATTTTCTTTGAA
TCTTTCTGTGTCTTCACATTTTTCTACAGTGAATTTAATCAAATAGTAAAGTTGTTGTAAAAATAAAAGTGGATTTAGAAAGATCCAGTT
CTTGAAAACACTGTTTCTGGTAATGAAGCAGAATTTAAGTTGGTAATATTAAGGTGAATGTCATTTAAGGGAGTTACATCTTTATTCTGC
TAAAGAAGAGGATCATTGATTTCTGTACAGTCAGAACAGTACTTGGGTTTGCAACAGCTTTCTGAGAAAAGCTAGGTGTTTAATAGTTTA
ACTGAAAGTTTAACTATTTAAAAGACTAAATGCACATTTTATGGTATCTGATATTTTAAAAAGTAATGTTTGATTCTCCTTTTTATGAGT
TAAATTATTTTATACGAGTTGGTAATTTTTGCTTTTTAATAAAGTGGAAGCTTGCTTTTTTAACTCTTTTTTTATTGTTATTTTATAGAA
ATGCTTTTTGTTGGCCGGGCACAGTTGCTCATCCATGTAATCCCAGCACTGTGGGAGGCCGAGACGGGTGGATCACAAGGTCAGGAGATC
GAGACCATCCTGGCTAATGCGTTGAAACTCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCACCTGTAGTCCCAG
CTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCAGAGCTTGCAGTGAGACGAGCTTGTGCCA
CTGCACTCCAGCCTGGGCAACAGAGTAAGACTCAGTCTCAAAAAAAAAAAAAAGAGTGAAATGCTTTTTGTTTGCTTCAGTTTTTTATCA
TGGGGAGATCTTTTTCCTCAGAATTGTTTTCTTTTCACTGTAGGCTATTACAGGATACTTCAGGATCAAGATACAGAACCTTTTATTTAA
AGAGTTTGTAAAGTCAATGTGTTTGTTTGTGTCTCTGAGATTGACTTCAAGATAATAAGCTGCTAATTGTAAACAAAACAGTTACCCTCC
AGTATTAATATGACTCATTAGTGTGAGCCATTTGGGTCAAGTATGATTATGACCCTTGGACTTCCTGATGTAGTATTAAATTTCAACTCT
GGTTATCCATTAGCAATCTGTAGAGAACTTAATGAACCTGAACCCAGGCTTCTCTAGCTCTGGTAACGTGTGATTGTTTTCACTACAATA
TGATACATAGATGGTACCTTACTTTTCCTCATTCTTAATAGGTGTCTAAGAATGTCAGGGCAAAAGTATGGGCATTTTTCTTGCTATGTT
CAGAAAGTACAGTTCTCTCCAACTTGCAGAGGTACTTTTCTTGATTAAATAGCCTTCTCTAGCAACATCATTTTCAGACTAACTAAATGA
ATGCAGTATACTCTTTTCTTTGTTCTCAATCATTCACTCCTTATGCAAAGCCAATATAATTTTCCTCATACCTTATGCTTGAGGATATTG
TTGAAGAACACTTCCTGGAACACTTCTCACTTGTGATGCTGTACTAATTTTTTTTTTTTAATTTAAGCTAGTATACTAAGTGAACACCAT
GGTCAGTTGTGAGCATTTTGGTTTCCGCAAAGGATGGATGGTGAGCATCATGGGAAAGCTGTAGTTTAGTGACTTAGCCCTTAGTGATTA
ATAGATTTGCATGTACATAGAAGTCTTTGTTGGCCTTATAATCTGCTGTTATATTTGGCATGGATTTTCATGGTTTTGAGAATGACATCC
TGGCCCTGTGGTCCCCGAGGGTCATGGTCCTTGTGACCTGGCCCCTGTTCACTGCCCCCTTCGCTAGCACGAGTTGCTGTGCAGGGCTGG
AGGTAGCTACCATGGCTTGTTTCAAGGAAGGAAACTCTGGTACGGTGGCACCCTCAGGAGTGGAGGACAGTGAACTTCCTTGAAGAGGGA
GTGACTAAGGTGACCTCCAACCTGCCCTGAGCCAGCTGCCCTGCAGGTGCCACGTGAGCCTGCTCTGGCATCCACAGGATGCTCCTGGAG
CCTCTTCTCTGGCTGCTACCTCAGGGCATGGTTGTGGCCCCACCAACACCTATTTTCCAAATAATTATTCATTCTTGTGACAGTGGCCTG
AACATGTTTTTAATTTTCTCAACAAGCATTTAGCCAGCACTTATCCAGTGAAACAATTTGATAAGGTTTCAAGGAGTATCTGATGGGTTA
GGAAGTCACGAAATGAGGAGTTCTTGCCACATTTGCAGAGTCCCTCCTTGATAAGGTTTGGCGGTGTCCCCACCCAAATCTCATGTTGAA
TTGTAGTTCCCATAATCCCCACATGTTGTGGGAGGGACCCAGTGGGAGGTAATTAAATCATGGGGGTGGTTACCCCCACACTGCTGTTCT
CATGATACTGAGTTCTCACAAGTCCTGTTTGTTTTATAAGGGGCTTTTCCCCCTTTTGCTCAACACTTCTTCCTGCCATCATGTGAAGAA
GGACGTGTTTGTTTCCCCTTCTGCCACGATTGTAAGTTTCCTGAGGCCTTCCCAGCTATGTGGAACTGTGAGTTAATTAAACCTCTTTCC
TTTATAAATTACCCAGTCATGGGCAGTCCTTTACAGCAGCATGAGAATGGACTAATACACTCCTCAAATGTTTTGAAGATTGTTGCACCT
TGGAACTACCAGTGTGCACACAATCTGGCTCAATGTATATATTGGCCCAGCAAGGCAAAGAACTGAAGTTCCAGGATGGAAGAACCTGTG
TTCTCCTCATAATAGTATAGAATAATTCAAGATAGGCAAGAAGGACAGCAGTAAATGAAGACCATGGAAGAAAAGAAGGAATGCCAAAGA
TCGAGGAAATCTACCAAGACTAGTAGGGTAGTCCAGAAGAAGCTGTTTCAGGGCCTGTTGCCAGCTATGCCTTTGAGAACCTCGGGATCC
CAAAGAATGAGGGGAATTTCTTCAGAAAGACAATCTCGGCATGCATTATTTCTTTGTTTTGAAGATTCACTCATGTTGCATGCATCTGTA
GCTTGTGCCTTTTTTATTGCCTAGTAGTATTCTGTCATATGCCTATCTTACAATTTGATTATCTATTCACCTGTTGATGAATGTTTGAAT
TTTTTCCATTTGAGGAATTTTATGAATAAAGCTGCTATAAGCATGAAATTACAAGTCTTTTTGTGAACATATTTTCACTTGTGCAAATGC
CTATACTCCCACCAGTAATTTGTAAGAATTCTTGACAAAGCTTGGTATTGTCAGCGTTTTTAATTTTAGCCATTCTATTGGGTATATTTT
GATATCTCGTGGTTTTGATTTGCATTTTTCTGATTAAAGATGTTGAACTTCTTTTCATGTGCTTATTGGCCATTCACATATTTCGTGAAC
TATCTGTACAAATATTTTTGTTTATTAAAAAATTAGATTGTTTTGTTTTATTATTGAATAGTAAGAATTGTTTATATATTCTGGATACAC
TCTTTTTCAGATATGTGTGTTGTGACTATTCTTAGTCTTTAGCTTGCCTTTTCATTTTCTTAATTATGTCTTTCAAAGAACAAGTTTTTC
ATTTTGACGAAGCCTAGTTTATCAATTTTTTTTATGGTTGGTGCTTTTTGTGTGTTCCAAGAAATCTTTGCCTACTCATTTAATTACCTG
TGTGCCCTTGTCAAAATCATTTAATTTTGACTACTCACTTAATTACCTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATTTA
CTGTTTATCTGTGAATCTGGATGATCTATTTATGTCATTTATCTATGTGTCTCTTCTTATGCCAGTACCCCACTGTCTTGATTATTGTGG
CTTTATGGTGTCTTGAAATTAAGTATTGTTAAGCTTTGCAATCTTTTCCAAGATTGTTTTGGCTATAGGTCCTTTCTTTATAAAGTTTAT
ATTAAGCTTCTCCATTTTTCTTTAAGAAAAAATCTGCTGGAATGGCACTGAATTTTTAGGTCGATTTGGGAAGAATTGACAATATTGAAC
CTTTCAATCGATGGACATGGTATGTTTCTGCATTTATTTGGGCCTTTTAAAATTTATCTCAGCAATATTTTGTAGTTTTAGTGAAGAAGT
CTTGTATATATCTTTTGTTAAATGTATTCCTAAATATTTTGTGGAAATGTTACTGTAAATAGTACTTTAATTTCATTTTTAAGTTTATTG

>102570_102570_4_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000374126_MTAP_chr9_21815432_ENST00000380172_length(amino acids)=283AA_BP=11
MNQPGGAAAPQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVI
VTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSR
AESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNL

--------------------------------------------------------------
>102570_102570_5_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000374126_MTAP_chr9_21815432_ENST00000460874_length(transcript)=1257nt_BP=132nt
GGCGGCGGCGGCGGCGGCGGCGGCGGCATTGTGCGCGCACCAGCAGCCCGGCCCGGGAGGAGCAGGACGCGCCGGGGCCGCCTCCTCCCG
CACGGACCCATGAACCAGCCGGGCGGCGCGGCGGCTCCGCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAA
GGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTC
CTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACA
CATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACC
ACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAA
ACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTT
AGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAG
GCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTA
AAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTC
CATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAAT
TCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTG
TAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACA

>102570_102570_5_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000374126_MTAP_chr9_21815432_ENST00000460874_length(amino acids)=283AA_BP=11
MNQPGGAAAPQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVI
VTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSR
AESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNL

--------------------------------------------------------------
>102570_102570_6_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000374126_MTAP_chr9_21815432_ENST00000580900_length(transcript)=1552nt_BP=132nt
GGCGGCGGCGGCGGCGGCGGCGGCGGCATTGTGCGCGCACCAGCAGCCCGGCCCGGGAGGAGCAGGACGCGCCGGGGCCGCCTCCTCCCG
CACGGACCCATGAACCAGCCGGGCGGCGCGGCGGCTCCGCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAA
GGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTC
CTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACA
CATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACC
ACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAA
ACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTT
AGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAG
GCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTA
AAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTC
CATAACCTGAAGATGATCAAGTTCCAGATGATCCTCAGTGAGGGATACCATCCTTTCAATATTCAAGAGTCACCCTTCTACAGAGGACTC
CTAGACTTCCCATCAGTGGGACATGGCAGAGGTGAAATCCTGCCCCTGTCTCCCTTAGACCTGGCTGGATACTGCTTCCAACAACCCATG
CAGCCACCCTGCCCTGACAGCTAGCAAGAGGCCAAGACCCACAGAACAATCACCATCACACCTCTGTCAGCAGGAAGCAGTTACAGAAGA
CTGACCTTCATCCAGTTTCCCAAAGAATTGGGTCATGGATTTTTGCGGGGGAAAATGTTAGAGTAGGTAATTAGGCAGACATGAGTAAGG
GAGGAGAGACCCCCTCCAACTAGGAATGTCAGGTGAGCATCAGATGATCATCAGGTGGTTGTTAAACTCTCTCTCTAAAATAATAATAGG
TTGCAACTGGCAGCAGGGAAAGACAATCTCCCAATAGATAGAAAAGTCCTGAAGCTGGTGATCAGCAGCTTCCTAGTAAGATCTCAGGAT
TTGGGCAAGCAGGCTCAAACATGGGCACTAAGAGGCAAAATCGTGGAGTTTAACTGGTATACAGACTTCCTCTAAAAACACATGACTCAT

>102570_102570_6_ZNF618-MTAP_ZNF618_chr9_116638693_ENST00000374126_MTAP_chr9_21815432_ENST00000580900_length(amino acids)=334AA_BP=11
MNQPGGAAAPQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVI
VTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSR
AESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNF618-MTAP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF618-MTAP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF618-MTAP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource