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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF644-ORC4 (FusionGDB2 ID:102629)

Fusion Gene Summary for ZNF644-ORC4

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF644-ORC4
Fusion gene ID: 102629
HgeneTgene
Gene symbol

ZNF644

ORC4

Gene ID

84146

5000

Gene namezinc finger protein 644origin recognition complex subunit 4
SynonymsBM-005|MYP21|NatF|ZEP-2ORC4L|ORC4P
Cytomap

1p22.2

2q23.1

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 644zinc finger motif enhancer binding protein 2origin recognition complex subunit 4origin recognition complex, subunit 4 homolog
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000337393, ENST00000347275, 
ENST00000361321, ENST00000370440, 
ENST00000467231, 		ENST00000264169, 
ENST00000536575, ENST00000540442, 
ENST00000488761, ENST00000542387, 
ENST00000392857, ENST00000392858, 
ENST00000535373, 
Fusion gene scores* DoF score7 X 7 X 6=2947 X 7 X 5=245
# samples 88
** MAII scorelog2(8/294*10)=-1.877744249949
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/245*10)=-1.61470984411521
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF644 [Title/Abstract] AND ORC4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF644(91447866)-ORC4(148716435), # samples:1
Anticipated loss of major functional domain due to fusion event.ZNF644-ORC4 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ZNF644-ORC4 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
ZNF644-ORC4 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ZNF644 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ORC4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-HC-A632ZNF644chr1

91447866

-ORC4chr2

148716435

-


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Fusion Gene ORF analysis for ZNF644-ORC4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000337393ENST00000264169ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-5UTRENST00000337393ENST00000536575ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-5UTRENST00000337393ENST00000540442ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-5UTRENST00000347275ENST00000264169ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-5UTRENST00000347275ENST00000536575ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-5UTRENST00000347275ENST00000540442ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-5UTRENST00000361321ENST00000264169ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-5UTRENST00000361321ENST00000536575ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-5UTRENST00000361321ENST00000540442ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-5UTRENST00000370440ENST00000264169ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-5UTRENST00000370440ENST00000536575ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-5UTRENST00000370440ENST00000540442ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-intronENST00000337393ENST00000488761ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-intronENST00000337393ENST00000542387ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-intronENST00000347275ENST00000488761ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-intronENST00000347275ENST00000542387ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-intronENST00000361321ENST00000488761ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-intronENST00000361321ENST00000542387ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-intronENST00000370440ENST00000488761ZNF644chr1

91447866

-ORC4chr2

148716435

-
5CDS-intronENST00000370440ENST00000542387ZNF644chr1

91447866

-ORC4chr2

148716435

-
5UTR-3CDSENST00000467231ENST00000392857ZNF644chr1

91447866

-ORC4chr2

148716435

-
5UTR-3CDSENST00000467231ENST00000392858ZNF644chr1

91447866

-ORC4chr2

148716435

-
5UTR-3CDSENST00000467231ENST00000535373ZNF644chr1

91447866

-ORC4chr2

148716435

-
5UTR-5UTRENST00000467231ENST00000264169ZNF644chr1

91447866

-ORC4chr2

148716435

-
5UTR-5UTRENST00000467231ENST00000536575ZNF644chr1

91447866

-ORC4chr2

148716435

-
5UTR-5UTRENST00000467231ENST00000540442ZNF644chr1

91447866

-ORC4chr2

148716435

-
5UTR-intronENST00000467231ENST00000488761ZNF644chr1

91447866

-ORC4chr2

148716435

-
5UTR-intronENST00000467231ENST00000542387ZNF644chr1

91447866

-ORC4chr2

148716435

-
Frame-shiftENST00000337393ENST00000392857ZNF644chr1

91447866

-ORC4chr2

148716435

-
Frame-shiftENST00000337393ENST00000392858ZNF644chr1

91447866

-ORC4chr2

148716435

-
Frame-shiftENST00000337393ENST00000535373ZNF644chr1

91447866

-ORC4chr2

148716435

-
Frame-shiftENST00000370440ENST00000392857ZNF644chr1

91447866

-ORC4chr2

148716435

-
Frame-shiftENST00000370440ENST00000392858ZNF644chr1

91447866

-ORC4chr2

148716435

-
Frame-shiftENST00000370440ENST00000535373ZNF644chr1

91447866

-ORC4chr2

148716435

-
In-frameENST00000347275ENST00000392857ZNF644chr1

91447866

-ORC4chr2

148716435

-
In-frameENST00000347275ENST00000392858ZNF644chr1

91447866

-ORC4chr2

148716435

-
In-frameENST00000347275ENST00000535373ZNF644chr1

91447866

-ORC4chr2

148716435

-
In-frameENST00000361321ENST00000392857ZNF644chr1

91447866

-ORC4chr2

148716435

-
In-frameENST00000361321ENST00000392858ZNF644chr1

91447866

-ORC4chr2

148716435

-
In-frameENST00000361321ENST00000535373ZNF644chr1

91447866

-ORC4chr2

148716435

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000347275ZNF644chr191447866-ENST00000392857ORC4chr2148716435-64432462611331356
ENST00000347275ZNF644chr191447866-ENST00000392858ORC4chr2148716435-26792462611331356
ENST00000347275ZNF644chr191447866-ENST00000535373ORC4chr2148716435-26792462611331356
ENST00000361321ZNF644chr191447866-ENST00000392857ORC4chr2148716435-65413443591429356
ENST00000361321ZNF644chr191447866-ENST00000392858ORC4chr2148716435-27773443591429356
ENST00000361321ZNF644chr191447866-ENST00000535373ORC4chr2148716435-27773443591429356

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000347275ENST00000392857ZNF644chr191447866-ORC4chr2148716435-0.0005259330.9994741
ENST00000347275ENST00000392858ZNF644chr191447866-ORC4chr2148716435-0.000541460.9994585
ENST00000347275ENST00000535373ZNF644chr191447866-ORC4chr2148716435-0.000541460.9994585
ENST00000361321ENST00000392857ZNF644chr191447866-ORC4chr2148716435-0.0005190490.999481
ENST00000361321ENST00000392858ZNF644chr191447866-ORC4chr2148716435-0.0005300580.99946994
ENST00000361321ENST00000535373ZNF644chr191447866-ORC4chr2148716435-0.0005300580.99946994

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Fusion Genomic Features for ZNF644-ORC4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZNF644-ORC4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:91447866/chr2:148716435)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneORC4chr1:91447866chr2:148716435ENST0000053657501167_740353.0Nucleotide bindingATP
TgeneORC4chr1:91447866chr2:148716435ENST0000054044221367_741363.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF644chr1:91447866chr2:148716435ENST00000337393-261038_1060141328.0Zinc fingerC2H2-type 7
HgeneZNF644chr1:91447866chr2:148716435ENST00000337393-26410_432141328.0Zinc fingerC2H2-type 1
HgeneZNF644chr1:91447866chr2:148716435ENST00000337393-26448_470141328.0Zinc fingerC2H2-type 2
HgeneZNF644chr1:91447866chr2:148716435ENST00000337393-26496_518141328.0Zinc fingerC2H2-type 3
HgeneZNF644chr1:91447866chr2:148716435ENST00000337393-26525_548141328.0Zinc fingerC2H2-type 4
HgeneZNF644chr1:91447866chr2:148716435ENST00000337393-26586_609141328.0Zinc fingerC2H2-type 5
HgeneZNF644chr1:91447866chr2:148716435ENST00000337393-26963_987141328.0Zinc fingerC2H2-type 6
HgeneZNF644chr1:91447866chr2:148716435ENST00000347275-241038_10607106.0Zinc fingerC2H2-type 7
HgeneZNF644chr1:91447866chr2:148716435ENST00000347275-24410_4327106.0Zinc fingerC2H2-type 1
HgeneZNF644chr1:91447866chr2:148716435ENST00000347275-24448_4707106.0Zinc fingerC2H2-type 2
HgeneZNF644chr1:91447866chr2:148716435ENST00000347275-24496_5187106.0Zinc fingerC2H2-type 3
HgeneZNF644chr1:91447866chr2:148716435ENST00000347275-24525_5487106.0Zinc fingerC2H2-type 4
HgeneZNF644chr1:91447866chr2:148716435ENST00000347275-24586_6097106.0Zinc fingerC2H2-type 5
HgeneZNF644chr1:91447866chr2:148716435ENST00000347275-24963_9877106.0Zinc fingerC2H2-type 6
HgeneZNF644chr1:91447866chr2:148716435ENST00000361321-241038_10607106.0Zinc fingerC2H2-type 7
HgeneZNF644chr1:91447866chr2:148716435ENST00000361321-24410_4327106.0Zinc fingerC2H2-type 1
HgeneZNF644chr1:91447866chr2:148716435ENST00000361321-24448_4707106.0Zinc fingerC2H2-type 2
HgeneZNF644chr1:91447866chr2:148716435ENST00000361321-24496_5187106.0Zinc fingerC2H2-type 3
HgeneZNF644chr1:91447866chr2:148716435ENST00000361321-24525_5487106.0Zinc fingerC2H2-type 4
HgeneZNF644chr1:91447866chr2:148716435ENST00000361321-24586_6097106.0Zinc fingerC2H2-type 5
HgeneZNF644chr1:91447866chr2:148716435ENST00000361321-24963_9877106.0Zinc fingerC2H2-type 6
HgeneZNF644chr1:91447866chr2:148716435ENST00000370440-261038_1060141328.0Zinc fingerC2H2-type 7
HgeneZNF644chr1:91447866chr2:148716435ENST00000370440-26410_432141328.0Zinc fingerC2H2-type 1
HgeneZNF644chr1:91447866chr2:148716435ENST00000370440-26448_470141328.0Zinc fingerC2H2-type 2
HgeneZNF644chr1:91447866chr2:148716435ENST00000370440-26496_518141328.0Zinc fingerC2H2-type 3
HgeneZNF644chr1:91447866chr2:148716435ENST00000370440-26525_548141328.0Zinc fingerC2H2-type 4
HgeneZNF644chr1:91447866chr2:148716435ENST00000370440-26586_609141328.0Zinc fingerC2H2-type 5
HgeneZNF644chr1:91447866chr2:148716435ENST00000370440-26963_987141328.0Zinc fingerC2H2-type 6
TgeneORC4chr1:91447866chr2:148716435ENST0000026416931467_7475437.0Nucleotide bindingATP
TgeneORC4chr1:91447866chr2:148716435ENST0000039285731467_7475437.0Nucleotide bindingATP
TgeneORC4chr1:91447866chr2:148716435ENST0000039285831467_7475437.0Nucleotide bindingATP
TgeneORC4chr1:91447866chr2:148716435ENST0000053537341567_7475437.0Nucleotide bindingATP


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Fusion Gene Sequence for ZNF644-ORC4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102629_102629_1_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000347275_ORC4_chr2_148716435_ENST00000392857_length(transcript)=6443nt_BP=246nt
CGGGGCGGGCCGAGAGCAGTCACCAACCCCTCTCGTTGAGGCTGCTCGGTTGTGGCCAGAAACGCTGGCTCTGGCATTAACTGTCTACAC
CCCTCCCCTTACTTGGGACAGGACCGCATAGCCCTCCCCTCCCCCCGTCCTGCAAGATCTTATGCGGCTAGGTGCCTGGGAAGTAACAGC
AAGAGGTTTGATTTAATTTTGGATGAGATCGTTCTTGCAGCAAGATGTTAATAAGACAAAATCTAGTTAATAAATCATGCTTTGAAAGAA
CTCATGGAAATAGAAGAAGTGAGTGAAAATGTATTACAAGTTCACTTAAATGGACTGCTGCAGATCAATGACAAAATCGCCCTAAAGGAA
ATCACAAGGCAGTTAAATCTGGAAAATGTAGTTGGAGATAAAGTTTTTGGAAGCTTTGCTGAAAACCTTTCATTTCTTCTGGAAGCTTTA
AAAAAAGGTGACCGAACTAGCAGTTGCCCAGTGATCTTCATATTAGATGAATTTGATCTTTTTGCTCATCATAAAAACCAAACACTTCTC
TATAATCTTTTTGACATTTCTCAGTCTGCACAGACCCCAATAGCAGTTATTGGTCTTACATGTAGATTGGATATTTTGGAACTCTTAGAA
AAAAGAGTGAAGTCAAGATTTTCTCACCGGCAGATACACTTAATGAATTCATTTGGTTTTCCACAGTATGTTAAAATATTTAAAGAACAG
TTATCTCTACCTGCAGAGTTTCCAGACAAGGTTTTTGCTGAGAAGTGGAATGAAAATGTTCAGTATCTCTCAGAAGATAGAAGTGTGCAA
GAAGTACTACAGAAGCATTTCAATATCAGCAAAAACCTGCGGTCATTACACATGCTATTGATGCTTGCTTTAAATCGAGTAACAGCATCG
CACCCATTTATGACTGCCGTAGATCTAATGGAAGCAAGCCAACTGTGTAGCATGGACTCGAAAGCAAATATTGTACATGGTCTATCAGTC
TTGGAAATCTGTCTTATAATAGCAATGAAACATTTAAATGACATCTATGAGGAAGAGCCATTTAATTTTCAAATGGTCTATAATGAGTTT
CAGAAGTTTGTTCAAAGGAAAGCACATTCCGTTTATAATTTTGAAAAACCTGTTGTCATGAAGGCTTTTGAACACTTGCAGCAATTAGAA
TTAATAAAGCCCATGGAAAGAACTTCAGGAAATTCACAGAGAGAGTACCAGCTGATGAAACTGCTTTTGGATAATACTCAAATTATGAAT
GCTCTGCAGAAATATCCCAACTGTCCTACAGATGTGAGGCAGTGGGCAACATCCTCACTAAGCTGGTTATGAATATAACCAGTGACTTCA
ACTTTGGCATTTCATTCATACTTCTGTAGAGAACGGAAAACTATTGTCCATTAACATGATATGCTAAACATTCTATAAACATTCTTGTAT
TTATGTGAGACTTGCCCATCTACTGTCTTGGCTGTGTCTTGCCTTTTAATCATGAACAGTTACATGATTTATAATTTCACTGATTGAGAT
TACTTTGTAAGTAGCTGTTCAGAAGAATAAAATATGACTGTTTTAGGGACTAGACCATGTGCTTTTTTAACACTTATATATATAATGGTC
TATTTGAAGAGCTCACTTCAACCTAACAGCTAGATGTCTTTACAAACCTTAAACCAAAGGAGTAAAAAAAACAATGGTAAGCACTGAAGT
ATAATAAGTAACCTTTGGTACAGCAGGTTTGCTGCAGTGTTTTTTTCTGTCCACATGCAAATTTTGGATTCTATCCCAGACCCAGGTTTT
CTAGTTCAGAAGACTAACCAGCTTAGTCAGAAGATGGTTCCATGGAAGAAAAAGGCCAAGGAGTTTGAAGATTTTTCTTCTAGACATCTC
AAAATGTGGTACTCATACCATCCACATCAGAATCCCTTGTAGGATTTTCTAAAATTACAGATTGTTGAGCCTACCATAGGTCAAAAGGAC
TGGAATTTTCCTTCTTAACAAGTATAGTCATGGCACCACGTAACATTTTGGTCAATGACATTGTATAAAGGGTGGTCTCATAAGATTATA
CCATATTTTTACTGTACCTTTTCTATGTCTAAATATACAAATGTTTTACCATTGTGTTACAGTTGCCTACAGTATGATTACAGTAACATT
CTGTACAGTGCTATAGCTGAAGAGTAATAGGCTAGGCTATCTGTATAGCCTAAGTGTGTAACAGGCTATATACATATCATCAGGGTCTGT
GTAAGTATACTCTGTGATGTTCATACAGTGATGAAATCACCCAAAGACACATTTCTCAGAACGTAGCCCCATCATGAAGTGACGTGACTA
CCAGAGATTTCTGGAAAAGCACTCCCAAAAGTAATGAGATGTGTATGGCAATGTTAACTGAACCTGTTTGTATTAAAAAGTAAATCCCTA
TGAGGAATGTGGAAATGTCCGTCAAAGCATTGTCTTTTAAGTAAGTTCCAAGATCCATGAATTAACAGAGGCATATATTTAAAATGAAAT
TTAATGAGCACTTAGTGACTTCATTTGTTCAAGAATATTTGATTTCCTATTGTGTGCATGGGAGGTTTACAAAAGACAGACTGTCCCTAT
GCTTGTGCAGCTTACAATCTATTTAACTATTAGAGGCCCTGTGAGATGTAGGCAGTTATTTACAGATGAGAAAACTAACACAGCAGTGGC
AATGCTGGGAATGGCCAACAGGCTTGGAATTCAACTCAGTTTAGCACCAAAGCCAGTGCTATTAAGACCTGAAGTTCAACAGTGGATTCC
TTACCAAATAGTTTTTAAAGTATGCTCTAAGGAACAATGTTTTAATGAAATCTTGGATACAAAGTGGAATAAAAGGTTTCTGAGCATAAA
GTAGCTCTTCAGTAGTTACAACCTATTCTTTTGCATACATAGCCTTTCCTTCCCTGCAAAAAGTTAAGCCTGCTAAGTATTCAGATCCCT
GTCATTTACTTCTCAGCAGTCTCATTCAAGCTAAGGCTTGCATACTCAATCTGTGCCGTAGTCTACACATTTTTAGGGGATATTTCACCA
AAATACTTGACATGGTAACATCACTATTATATACTAGAAGCAAGAATTTTACACTTATGCTCTAAGTGATCCTTTTAAAAATTTTCTGAA
CTATTTGAGGAAAGTATTATTTGTCTTAAAGGGTAACAGCCTCATGAAATGACTTGAGGATTCCAATTTCTTATTAGCTTAAGATGTCAC
TTAAAAGCTGACAGCCCTCATCTGTCTCATTGGCTACATAAGAGCTGCAGAAGATCCATCAATAACCAAGTATAAAGAAAGATTTTAAGA
CTAAGTACCAATTGAGGTAAACATGAAACCGTTATAAAGCAAATTAAAAAAAAATACATTAGGAAAAGTTACACAAATGAAGTGTACGCC
TATTATATTCCCAAGGCATTTTTGTGGGGAGGAACAGTGCTGCTTGTTGGCCTTTCCATATTCCCTCATACAAAAATGCTAAAATCTATT
CGCAAGAGTTTTGAGCTAACTTCGTCTCTTAAATTGCTTTAATTGTCATCAATAAAAACAAATATGAAAAACCCTAGTTTAAAAAGCGGT
TCAAGAATAATGTAAACTTATACATATAGCTTATTTTCTTCATTTACTAGAGGAGGAAAAATAGAACCAAAAAATGCATGAACTCCTGCT
TTTCAATCTGATTACCTCAAACTGAAAAGCAGGTGAAAGGAGGAATATTTCAGTGTGTTTTTACATCTGAATCCAAGGGATCCAAGTGGC
CCAGCAGAAACGGAATTCTTGTTAAAATGACTGATTCTCGTGCATGTGAAAGGCTCTGGGGAATGAATACCTGTTTGGTCCAAACTTACT
GTATCATAATGCTGTATATGTTGAAAACGTAATACCTGTTAATGTCCTAATGAATCACGTTTTGCAGAAAACACCGTAAGAAACACTTCA
GTCTTTCTGTAGTTTCCATGCATATTTCACCATGGTTCGCACTCTGATCCTCATCTGGTTTAGAAAGCAATTCAGTTTCTTTCAAACCAC
CATAACCTAAGTGCTGCCCCATCCTTCACCTTTACCCTAGAAAATCTGAGAATCCATTGGTGTGTACTGTGTGACACAATGCCAACAAGC
CTCTGGTTTCTAATACTGGCAGGACCAACACACATACTTTAGTGGGAATATAATCTGTTTAGACGATAATAGAGGGAAATGCCATAATTA
ACAAATCTCCCTTCACTCACCACTATCCTCATTCTTGCAGTTGTCAAGGTGTAAGCCTCACTGTAAGTTACAAAGCTACCACTCCCCTCT
TTAAGAACACATAGCTTAGGATTGCCTTGGCGATGTGGGCTCTTTTTTGGTTCCATATGAACTTAAGTAGTTTTTTCCAATTCTGTGAAG
AAAGTCATTGGTAGCTTGATGGGGATGGCATTGAATCTGTAAATTACCTTGGGCAGTATGGCCATTTTCACAATATTGATTCTTCCTACC
CAAGAGCATGGAATGTTCTTCCATTTGTTTGTATCCTCTTTTATTTCCTTGAGCAGTAGCTTGTAGTTCTCCTTGAAGAGGTCCTTCACA
TCCCTTGTAAGTTGGATTCCTAGGTATTTTATTCTCTTTGAAGCAATTGTGAATGGGAGTTCACTCATGATTTGGCTCTCTGTTTGTCTG
TTGTTGGTGTATAAGAATGCTTGTGATTTTTGTACATTGATTTTGTATCCTGAGACTTTGCTGAAGTTGCTTATCAGCTTAAGGAGATTT
TGGGCTGAGACGATGGGGTTTTCTAGATATACAATCATGTCGTCTGCAAACGGACAATTTGACTTCCTCTTTTCCTAATTGAATACCCTT
TATTTCCTTCTCCTGCCTAATTGCCCTGGCCAGAACTTCCAACACTATGTTGAATACGAGTGGTGAGAGAGGGCATCCCTGTCTTGTGCC
AGTTTTCAAAGGGAATGCTTCCAGTTTTTGCCCATTCAGTATGATATTGGCTGTGGGTTTGTCATAGATAGCTCTTATTATTTTGAAATA
CACCCCATCAATCCCTAATTTATTGAGAGTTTTTAGCATGAAGGGTTGTTGAATTTTGTCAAAGGCTTTTTCTGCATCTATTGAGATAAT
CATGTGTTTTTTGTCTTTGGCTCTGTTTATATGCTGGATTACATTCATTGATTTGCGTATATTGAACCAGCCTTGCATCCCAGGGATGAA
GCCCACTTGATCATGGTGGATAAGCTTTTTGATGTGCTGCTGGATTCGTTTTGCCAGTATTTTATCCAGTTAGAATGGCAATCATTAAAA
AGTCAGGAAACAACAGGTGCTGGAGAGGATGTGGAGAAATAGGAACACTTTCACACTGTTGGTGGGACTGTAAACTAGTTCAACCATTGT
GGAAGTCAGTGTGGCGATTCCTCAGGGATCTAGAACTGGAAACACCATTTGACCCAGCCATCCCATTACTGGGTATATACCCAAAGGACT
ATAAATCATGCTGCTATAAAGACACATGCACACGTATGTTTATTGTGGCATTATTCACAATAGCAAAGACTTGGAACCAACCCAAATGTC
CAACAATGATAGACTGGATTAAGAAAACGTGGCACATATACACCATGGAATACTATGCAGCCATAAAAAATGATGAGTTCATGTCCTTTG
TAGGGACATGGATGAAATTGGAAATCATCATTCTCAGTAAACTATCACAAGAACAAAAAACCAAACACCGCATATTCTCACTCATAGGTG
GGAATTGAACAATGAGATCACATGGACACAGGAAGGGGAATATCACACTCTGGGGACTGTTGTGGGGTGGGGGGATGGGGGAGGGATAGC
ATTAGGAGATATACCTAATGCTAGATGACGAGTTAGTGGGTGCAGCGCACCAGCATGGCACATGTATACCTATGTAACTAACCTGCACAA
TGTGCACATGTACCCTAAAACTTAAAGTATAAAAAAAAAAAAAAACATAGCTAAAGAAAAACTGCATATGCAAATCATACCGTATTCATT
TTTTTATTTAACTTGGGGATGGAATGGGGATAGCATACATTTTATTTGTACAATATTTAACAATCACTTATCCAAGGTGGGGTTTTATGG
GGATTTTAAGCTTTCTGTTAAATACTTGCAGAAAAAATAGCAAGTACGATTTGACAGTAGTACAATAACCTGTGCCCAAAACACAAGAAA
TACAGAGTAAAGCGAAAATAACTGCTTACCAATATTCTGAGAGGTAACAAATGGGATATGGGTTGAGACTGCATAAAAAACGTACTGCTG
GTTGAATATCTGAGGTAAATGATGTTCAATCAAGATGCTACTTGTATCATTTTGCCCATAAATGGATAAATAATTTTATGCATATCATAC

>102629_102629_1_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000347275_ORC4_chr2_148716435_ENST00000392857_length(amino acids)=356AA_BP=
MKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQ
TLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDR
SVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVY

--------------------------------------------------------------
>102629_102629_2_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000347275_ORC4_chr2_148716435_ENST00000392858_length(transcript)=2679nt_BP=246nt
CGGGGCGGGCCGAGAGCAGTCACCAACCCCTCTCGTTGAGGCTGCTCGGTTGTGGCCAGAAACGCTGGCTCTGGCATTAACTGTCTACAC
CCCTCCCCTTACTTGGGACAGGACCGCATAGCCCTCCCCTCCCCCCGTCCTGCAAGATCTTATGCGGCTAGGTGCCTGGGAAGTAACAGC
AAGAGGTTTGATTTAATTTTGGATGAGATCGTTCTTGCAGCAAGATGTTAATAAGACAAAATCTAGTTAATAAATCATGCTTTGAAAGAA
CTCATGGAAATAGAAGAAGTGAGTGAAAATGTATTACAAGTTCACTTAAATGGACTGCTGCAGATCAATGACAAAATCGCCCTAAAGGAA
ATCACAAGGCAGTTAAATCTGGAAAATGTAGTTGGAGATAAAGTTTTTGGAAGCTTTGCTGAAAACCTTTCATTTCTTCTGGAAGCTTTA
AAAAAAGGTGACCGAACTAGCAGTTGCCCAGTGATCTTCATATTAGATGAATTTGATCTTTTTGCTCATCATAAAAACCAAACACTTCTC
TATAATCTTTTTGACATTTCTCAGTCTGCACAGACCCCAATAGCAGTTATTGGTCTTACATGTAGATTGGATATTTTGGAACTCTTAGAA
AAAAGAGTGAAGTCAAGATTTTCTCACCGGCAGATACACTTAATGAATTCATTTGGTTTTCCACAGTATGTTAAAATATTTAAAGAACAG
TTATCTCTACCTGCAGAGTTTCCAGACAAGGTTTTTGCTGAGAAGTGGAATGAAAATGTTCAGTATCTCTCAGAAGATAGAAGTGTGCAA
GAAGTACTACAGAAGCATTTCAATATCAGCAAAAACCTGCGGTCATTACACATGCTATTGATGCTTGCTTTAAATCGAGTAACAGCATCG
CACCCATTTATGACTGCCGTAGATCTAATGGAAGCAAGCCAACTGTGTAGCATGGACTCGAAAGCAAATATTGTACATGGTCTATCAGTC
TTGGAAATCTGTCTTATAATAGCAATGAAACATTTAAATGACATCTATGAGGAAGAGCCATTTAATTTTCAAATGGTCTATAATGAGTTT
CAGAAGTTTGTTCAAAGGAAAGCACATTCCGTTTATAATTTTGAAAAACCTGTTGTCATGAAGGCTTTTGAACACTTGCAGCAATTAGAA
TTAATAAAGCCCATGGAAAGAACTTCAGGAAATTCACAGAGAGAGTACCAGCTGATGAAACTGCTTTTGGATAATACTCAAATTATGAAT
GCTCTGCAGAAATATCCCAACTGTCCTACAGATGTGAGGCAGTGGGCAACATCCTCACTAAGCTGGTTATGAATATAACCAGTGACTTCA
ACTTTGGCATTTCATTCATACTTCTGTAGAGAACGGAAAACTATTGTCCATTAACATGATATGCTAAACATTCTATAAACATTCTTGTAT
TTATGTGAGACTTGCCCATCTACTGTCTTGGCTGTGTCTTGCCTTTTAATCATGAACAGTTACATGATTTATAATTTCACTGATTGAGAT
TACTTTGTAAGTAGCTGTTCAGAAGAATAAAATATGACTGTTTTAGGGACTAGACCATGTGCTTTTTTAACACTTATATATATAATGGTC
TATTTGAAGAGCTCACTTCAACCTAACAGCTAGATGTCTTTACAAACCTTAAACCAAAGGAGTAAAAAAAACAATGGTAAGCACTGAAGT
ATAATAAGTAACCTTTGGTACAGCAGGTTTGCTGCAGTGTTTTTTTCTGTCCACATGCAAATTTTGGATTCTATCCCAGACCCAGGTTTT
CTAGTTCAGAAGACTAACCAGCTTAGTCAGAAGATGGTTCCATGGAAGAAAAAGGCCAAGGAGTTTGAAGATTTTTCTTCTAGACATCTC
AAAATGTGGTACTCATACCATCCACATCAGAATCCCTTGTAGGATTTTCTAAAATTACAGATTGTTGAGCCTACCATAGGTCAAAAGGAC
TGGAATTTTCCTTCTTAACAAGTATAGTCATGGCACCACGTAACATTTTGGTCAATGACATTGTATAAAGGGTGGTCTCATAAGATTATA
CCATATTTTTACTGTACCTTTTCTATGTCTAAATATACAAATGTTTTACCATTGTGTTACAGTTGCCTACAGTATGATTACAGTAACATT
CTGTACAGTGCTATAGCTGAAGAGTAATAGGCTAGGCTATCTGTATAGCCTAAGTGTGTAACAGGCTATATACATATCATCAGGGTCTGT
GTAAGTATACTCTGTGATGTTCATACAGTGATGAAATCACCCAAAGACACATTTCTCAGAACGTAGCCCCATCATGAAGTGACGTGACTA
CCAGAGATTTCTGGAAAAGCACTCCCAAAAGTAATGAGATGTGTATGGCAATGTTAACTGAACCTGTTTGTATTAAAAAGTAAATCCCTA
TGAGGAATGTGGAAATGTCCGTCAAAGCATTGTCTTTTAAGTAAGTTCCAAGATCCATGAATTAACAGAGGCATATATTTAAAATGAAAT
TTAATGAGCACTTAGTGACTTCATTTGTTCAAGAATATTTGATTTCCTATTGTGTGCATGGGAGGTTTACAAAAGACAGACTGTCCCTAT

>102629_102629_2_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000347275_ORC4_chr2_148716435_ENST00000392858_length(amino acids)=356AA_BP=
MKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQ
TLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDR
SVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVY

--------------------------------------------------------------
>102629_102629_3_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000347275_ORC4_chr2_148716435_ENST00000535373_length(transcript)=2679nt_BP=246nt
CGGGGCGGGCCGAGAGCAGTCACCAACCCCTCTCGTTGAGGCTGCTCGGTTGTGGCCAGAAACGCTGGCTCTGGCATTAACTGTCTACAC
CCCTCCCCTTACTTGGGACAGGACCGCATAGCCCTCCCCTCCCCCCGTCCTGCAAGATCTTATGCGGCTAGGTGCCTGGGAAGTAACAGC
AAGAGGTTTGATTTAATTTTGGATGAGATCGTTCTTGCAGCAAGATGTTAATAAGACAAAATCTAGTTAATAAATCATGCTTTGAAAGAA
CTCATGGAAATAGAAGAAGTGAGTGAAAATGTATTACAAGTTCACTTAAATGGACTGCTGCAGATCAATGACAAAATCGCCCTAAAGGAA
ATCACAAGGCAGTTAAATCTGGAAAATGTAGTTGGAGATAAAGTTTTTGGAAGCTTTGCTGAAAACCTTTCATTTCTTCTGGAAGCTTTA
AAAAAAGGTGACCGAACTAGCAGTTGCCCAGTGATCTTCATATTAGATGAATTTGATCTTTTTGCTCATCATAAAAACCAAACACTTCTC
TATAATCTTTTTGACATTTCTCAGTCTGCACAGACCCCAATAGCAGTTATTGGTCTTACATGTAGATTGGATATTTTGGAACTCTTAGAA
AAAAGAGTGAAGTCAAGATTTTCTCACCGGCAGATACACTTAATGAATTCATTTGGTTTTCCACAGTATGTTAAAATATTTAAAGAACAG
TTATCTCTACCTGCAGAGTTTCCAGACAAGGTTTTTGCTGAGAAGTGGAATGAAAATGTTCAGTATCTCTCAGAAGATAGAAGTGTGCAA
GAAGTACTACAGAAGCATTTCAATATCAGCAAAAACCTGCGGTCATTACACATGCTATTGATGCTTGCTTTAAATCGAGTAACAGCATCG
CACCCATTTATGACTGCCGTAGATCTAATGGAAGCAAGCCAACTGTGTAGCATGGACTCGAAAGCAAATATTGTACATGGTCTATCAGTC
TTGGAAATCTGTCTTATAATAGCAATGAAACATTTAAATGACATCTATGAGGAAGAGCCATTTAATTTTCAAATGGTCTATAATGAGTTT
CAGAAGTTTGTTCAAAGGAAAGCACATTCCGTTTATAATTTTGAAAAACCTGTTGTCATGAAGGCTTTTGAACACTTGCAGCAATTAGAA
TTAATAAAGCCCATGGAAAGAACTTCAGGAAATTCACAGAGAGAGTACCAGCTGATGAAACTGCTTTTGGATAATACTCAAATTATGAAT
GCTCTGCAGAAATATCCCAACTGTCCTACAGATGTGAGGCAGTGGGCAACATCCTCACTAAGCTGGTTATGAATATAACCAGTGACTTCA
ACTTTGGCATTTCATTCATACTTCTGTAGAGAACGGAAAACTATTGTCCATTAACATGATATGCTAAACATTCTATAAACATTCTTGTAT
TTATGTGAGACTTGCCCATCTACTGTCTTGGCTGTGTCTTGCCTTTTAATCATGAACAGTTACATGATTTATAATTTCACTGATTGAGAT
TACTTTGTAAGTAGCTGTTCAGAAGAATAAAATATGACTGTTTTAGGGACTAGACCATGTGCTTTTTTAACACTTATATATATAATGGTC
TATTTGAAGAGCTCACTTCAACCTAACAGCTAGATGTCTTTACAAACCTTAAACCAAAGGAGTAAAAAAAACAATGGTAAGCACTGAAGT
ATAATAAGTAACCTTTGGTACAGCAGGTTTGCTGCAGTGTTTTTTTCTGTCCACATGCAAATTTTGGATTCTATCCCAGACCCAGGTTTT
CTAGTTCAGAAGACTAACCAGCTTAGTCAGAAGATGGTTCCATGGAAGAAAAAGGCCAAGGAGTTTGAAGATTTTTCTTCTAGACATCTC
AAAATGTGGTACTCATACCATCCACATCAGAATCCCTTGTAGGATTTTCTAAAATTACAGATTGTTGAGCCTACCATAGGTCAAAAGGAC
TGGAATTTTCCTTCTTAACAAGTATAGTCATGGCACCACGTAACATTTTGGTCAATGACATTGTATAAAGGGTGGTCTCATAAGATTATA
CCATATTTTTACTGTACCTTTTCTATGTCTAAATATACAAATGTTTTACCATTGTGTTACAGTTGCCTACAGTATGATTACAGTAACATT
CTGTACAGTGCTATAGCTGAAGAGTAATAGGCTAGGCTATCTGTATAGCCTAAGTGTGTAACAGGCTATATACATATCATCAGGGTCTGT
GTAAGTATACTCTGTGATGTTCATACAGTGATGAAATCACCCAAAGACACATTTCTCAGAACGTAGCCCCATCATGAAGTGACGTGACTA
CCAGAGATTTCTGGAAAAGCACTCCCAAAAGTAATGAGATGTGTATGGCAATGTTAACTGAACCTGTTTGTATTAAAAAGTAAATCCCTA
TGAGGAATGTGGAAATGTCCGTCAAAGCATTGTCTTTTAAGTAAGTTCCAAGATCCATGAATTAACAGAGGCATATATTTAAAATGAAAT
TTAATGAGCACTTAGTGACTTCATTTGTTCAAGAATATTTGATTTCCTATTGTGTGCATGGGAGGTTTACAAAAGACAGACTGTCCCTAT

>102629_102629_3_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000347275_ORC4_chr2_148716435_ENST00000535373_length(amino acids)=356AA_BP=
MKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQ
TLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDR
SVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVY

--------------------------------------------------------------
>102629_102629_4_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000361321_ORC4_chr2_148716435_ENST00000392857_length(transcript)=6541nt_BP=344nt
GAGAACAGTGGTGCACTGTTTCCGCTGCCCTCGTTTGTCTAATTGGCCCAGACGCTCCACCAGCGCGAAGCTTCCCGGGAGCTCCTCGCT
GGCCACCCCCGCGGCCCGCAGCCCGGCAGAGGCGGGAAAGCAGCGCGCCTGCGCCGTGGGAACCGGGGCTGGAGGCGAAAAGCGGGGAGC
GGAGGGGGGCCGCTGGAGCCGAGTAGCGTACAGAGCGGCGTGTGACGCGGGGACGCCGCGTGCTCCCAACGTCGCCCCGGTTTGACGCAC
ACGGCACCAAACTGTTTGATTTAATTTTGGATGAGATCGTTCTTGCAGCAAGATGTTAATAAGACAAAATCTAGTTAATAAATCATGCTT
TGAAAGAACTCATGGAAATAGAAGAAGTGAGTGAAAATGTATTACAAGTTCACTTAAATGGACTGCTGCAGATCAATGACAAAATCGCCC
TAAAGGAAATCACAAGGCAGTTAAATCTGGAAAATGTAGTTGGAGATAAAGTTTTTGGAAGCTTTGCTGAAAACCTTTCATTTCTTCTGG
AAGCTTTAAAAAAAGGTGACCGAACTAGCAGTTGCCCAGTGATCTTCATATTAGATGAATTTGATCTTTTTGCTCATCATAAAAACCAAA
CACTTCTCTATAATCTTTTTGACATTTCTCAGTCTGCACAGACCCCAATAGCAGTTATTGGTCTTACATGTAGATTGGATATTTTGGAAC
TCTTAGAAAAAAGAGTGAAGTCAAGATTTTCTCACCGGCAGATACACTTAATGAATTCATTTGGTTTTCCACAGTATGTTAAAATATTTA
AAGAACAGTTATCTCTACCTGCAGAGTTTCCAGACAAGGTTTTTGCTGAGAAGTGGAATGAAAATGTTCAGTATCTCTCAGAAGATAGAA
GTGTGCAAGAAGTACTACAGAAGCATTTCAATATCAGCAAAAACCTGCGGTCATTACACATGCTATTGATGCTTGCTTTAAATCGAGTAA
CAGCATCGCACCCATTTATGACTGCCGTAGATCTAATGGAAGCAAGCCAACTGTGTAGCATGGACTCGAAAGCAAATATTGTACATGGTC
TATCAGTCTTGGAAATCTGTCTTATAATAGCAATGAAACATTTAAATGACATCTATGAGGAAGAGCCATTTAATTTTCAAATGGTCTATA
ATGAGTTTCAGAAGTTTGTTCAAAGGAAAGCACATTCCGTTTATAATTTTGAAAAACCTGTTGTCATGAAGGCTTTTGAACACTTGCAGC
AATTAGAATTAATAAAGCCCATGGAAAGAACTTCAGGAAATTCACAGAGAGAGTACCAGCTGATGAAACTGCTTTTGGATAATACTCAAA
TTATGAATGCTCTGCAGAAATATCCCAACTGTCCTACAGATGTGAGGCAGTGGGCAACATCCTCACTAAGCTGGTTATGAATATAACCAG
TGACTTCAACTTTGGCATTTCATTCATACTTCTGTAGAGAACGGAAAACTATTGTCCATTAACATGATATGCTAAACATTCTATAAACAT
TCTTGTATTTATGTGAGACTTGCCCATCTACTGTCTTGGCTGTGTCTTGCCTTTTAATCATGAACAGTTACATGATTTATAATTTCACTG
ATTGAGATTACTTTGTAAGTAGCTGTTCAGAAGAATAAAATATGACTGTTTTAGGGACTAGACCATGTGCTTTTTTAACACTTATATATA
TAATGGTCTATTTGAAGAGCTCACTTCAACCTAACAGCTAGATGTCTTTACAAACCTTAAACCAAAGGAGTAAAAAAAACAATGGTAAGC
ACTGAAGTATAATAAGTAACCTTTGGTACAGCAGGTTTGCTGCAGTGTTTTTTTCTGTCCACATGCAAATTTTGGATTCTATCCCAGACC
CAGGTTTTCTAGTTCAGAAGACTAACCAGCTTAGTCAGAAGATGGTTCCATGGAAGAAAAAGGCCAAGGAGTTTGAAGATTTTTCTTCTA
GACATCTCAAAATGTGGTACTCATACCATCCACATCAGAATCCCTTGTAGGATTTTCTAAAATTACAGATTGTTGAGCCTACCATAGGTC
AAAAGGACTGGAATTTTCCTTCTTAACAAGTATAGTCATGGCACCACGTAACATTTTGGTCAATGACATTGTATAAAGGGTGGTCTCATA
AGATTATACCATATTTTTACTGTACCTTTTCTATGTCTAAATATACAAATGTTTTACCATTGTGTTACAGTTGCCTACAGTATGATTACA
GTAACATTCTGTACAGTGCTATAGCTGAAGAGTAATAGGCTAGGCTATCTGTATAGCCTAAGTGTGTAACAGGCTATATACATATCATCA
GGGTCTGTGTAAGTATACTCTGTGATGTTCATACAGTGATGAAATCACCCAAAGACACATTTCTCAGAACGTAGCCCCATCATGAAGTGA
CGTGACTACCAGAGATTTCTGGAAAAGCACTCCCAAAAGTAATGAGATGTGTATGGCAATGTTAACTGAACCTGTTTGTATTAAAAAGTA
AATCCCTATGAGGAATGTGGAAATGTCCGTCAAAGCATTGTCTTTTAAGTAAGTTCCAAGATCCATGAATTAACAGAGGCATATATTTAA
AATGAAATTTAATGAGCACTTAGTGACTTCATTTGTTCAAGAATATTTGATTTCCTATTGTGTGCATGGGAGGTTTACAAAAGACAGACT
GTCCCTATGCTTGTGCAGCTTACAATCTATTTAACTATTAGAGGCCCTGTGAGATGTAGGCAGTTATTTACAGATGAGAAAACTAACACA
GCAGTGGCAATGCTGGGAATGGCCAACAGGCTTGGAATTCAACTCAGTTTAGCACCAAAGCCAGTGCTATTAAGACCTGAAGTTCAACAG
TGGATTCCTTACCAAATAGTTTTTAAAGTATGCTCTAAGGAACAATGTTTTAATGAAATCTTGGATACAAAGTGGAATAAAAGGTTTCTG
AGCATAAAGTAGCTCTTCAGTAGTTACAACCTATTCTTTTGCATACATAGCCTTTCCTTCCCTGCAAAAAGTTAAGCCTGCTAAGTATTC
AGATCCCTGTCATTTACTTCTCAGCAGTCTCATTCAAGCTAAGGCTTGCATACTCAATCTGTGCCGTAGTCTACACATTTTTAGGGGATA
TTTCACCAAAATACTTGACATGGTAACATCACTATTATATACTAGAAGCAAGAATTTTACACTTATGCTCTAAGTGATCCTTTTAAAAAT
TTTCTGAACTATTTGAGGAAAGTATTATTTGTCTTAAAGGGTAACAGCCTCATGAAATGACTTGAGGATTCCAATTTCTTATTAGCTTAA
GATGTCACTTAAAAGCTGACAGCCCTCATCTGTCTCATTGGCTACATAAGAGCTGCAGAAGATCCATCAATAACCAAGTATAAAGAAAGA
TTTTAAGACTAAGTACCAATTGAGGTAAACATGAAACCGTTATAAAGCAAATTAAAAAAAAATACATTAGGAAAAGTTACACAAATGAAG
TGTACGCCTATTATATTCCCAAGGCATTTTTGTGGGGAGGAACAGTGCTGCTTGTTGGCCTTTCCATATTCCCTCATACAAAAATGCTAA
AATCTATTCGCAAGAGTTTTGAGCTAACTTCGTCTCTTAAATTGCTTTAATTGTCATCAATAAAAACAAATATGAAAAACCCTAGTTTAA
AAAGCGGTTCAAGAATAATGTAAACTTATACATATAGCTTATTTTCTTCATTTACTAGAGGAGGAAAAATAGAACCAAAAAATGCATGAA
CTCCTGCTTTTCAATCTGATTACCTCAAACTGAAAAGCAGGTGAAAGGAGGAATATTTCAGTGTGTTTTTACATCTGAATCCAAGGGATC
CAAGTGGCCCAGCAGAAACGGAATTCTTGTTAAAATGACTGATTCTCGTGCATGTGAAAGGCTCTGGGGAATGAATACCTGTTTGGTCCA
AACTTACTGTATCATAATGCTGTATATGTTGAAAACGTAATACCTGTTAATGTCCTAATGAATCACGTTTTGCAGAAAACACCGTAAGAA
ACACTTCAGTCTTTCTGTAGTTTCCATGCATATTTCACCATGGTTCGCACTCTGATCCTCATCTGGTTTAGAAAGCAATTCAGTTTCTTT
CAAACCACCATAACCTAAGTGCTGCCCCATCCTTCACCTTTACCCTAGAAAATCTGAGAATCCATTGGTGTGTACTGTGTGACACAATGC
CAACAAGCCTCTGGTTTCTAATACTGGCAGGACCAACACACATACTTTAGTGGGAATATAATCTGTTTAGACGATAATAGAGGGAAATGC
CATAATTAACAAATCTCCCTTCACTCACCACTATCCTCATTCTTGCAGTTGTCAAGGTGTAAGCCTCACTGTAAGTTACAAAGCTACCAC
TCCCCTCTTTAAGAACACATAGCTTAGGATTGCCTTGGCGATGTGGGCTCTTTTTTGGTTCCATATGAACTTAAGTAGTTTTTTCCAATT
CTGTGAAGAAAGTCATTGGTAGCTTGATGGGGATGGCATTGAATCTGTAAATTACCTTGGGCAGTATGGCCATTTTCACAATATTGATTC
TTCCTACCCAAGAGCATGGAATGTTCTTCCATTTGTTTGTATCCTCTTTTATTTCCTTGAGCAGTAGCTTGTAGTTCTCCTTGAAGAGGT
CCTTCACATCCCTTGTAAGTTGGATTCCTAGGTATTTTATTCTCTTTGAAGCAATTGTGAATGGGAGTTCACTCATGATTTGGCTCTCTG
TTTGTCTGTTGTTGGTGTATAAGAATGCTTGTGATTTTTGTACATTGATTTTGTATCCTGAGACTTTGCTGAAGTTGCTTATCAGCTTAA
GGAGATTTTGGGCTGAGACGATGGGGTTTTCTAGATATACAATCATGTCGTCTGCAAACGGACAATTTGACTTCCTCTTTTCCTAATTGA
ATACCCTTTATTTCCTTCTCCTGCCTAATTGCCCTGGCCAGAACTTCCAACACTATGTTGAATACGAGTGGTGAGAGAGGGCATCCCTGT
CTTGTGCCAGTTTTCAAAGGGAATGCTTCCAGTTTTTGCCCATTCAGTATGATATTGGCTGTGGGTTTGTCATAGATAGCTCTTATTATT
TTGAAATACACCCCATCAATCCCTAATTTATTGAGAGTTTTTAGCATGAAGGGTTGTTGAATTTTGTCAAAGGCTTTTTCTGCATCTATT
GAGATAATCATGTGTTTTTTGTCTTTGGCTCTGTTTATATGCTGGATTACATTCATTGATTTGCGTATATTGAACCAGCCTTGCATCCCA
GGGATGAAGCCCACTTGATCATGGTGGATAAGCTTTTTGATGTGCTGCTGGATTCGTTTTGCCAGTATTTTATCCAGTTAGAATGGCAAT
CATTAAAAAGTCAGGAAACAACAGGTGCTGGAGAGGATGTGGAGAAATAGGAACACTTTCACACTGTTGGTGGGACTGTAAACTAGTTCA
ACCATTGTGGAAGTCAGTGTGGCGATTCCTCAGGGATCTAGAACTGGAAACACCATTTGACCCAGCCATCCCATTACTGGGTATATACCC
AAAGGACTATAAATCATGCTGCTATAAAGACACATGCACACGTATGTTTATTGTGGCATTATTCACAATAGCAAAGACTTGGAACCAACC
CAAATGTCCAACAATGATAGACTGGATTAAGAAAACGTGGCACATATACACCATGGAATACTATGCAGCCATAAAAAATGATGAGTTCAT
GTCCTTTGTAGGGACATGGATGAAATTGGAAATCATCATTCTCAGTAAACTATCACAAGAACAAAAAACCAAACACCGCATATTCTCACT
CATAGGTGGGAATTGAACAATGAGATCACATGGACACAGGAAGGGGAATATCACACTCTGGGGACTGTTGTGGGGTGGGGGGATGGGGGA
GGGATAGCATTAGGAGATATACCTAATGCTAGATGACGAGTTAGTGGGTGCAGCGCACCAGCATGGCACATGTATACCTATGTAACTAAC
CTGCACAATGTGCACATGTACCCTAAAACTTAAAGTATAAAAAAAAAAAAAAACATAGCTAAAGAAAAACTGCATATGCAAATCATACCG
TATTCATTTTTTTATTTAACTTGGGGATGGAATGGGGATAGCATACATTTTATTTGTACAATATTTAACAATCACTTATCCAAGGTGGGG
TTTTATGGGGATTTTAAGCTTTCTGTTAAATACTTGCAGAAAAAATAGCAAGTACGATTTGACAGTAGTACAATAACCTGTGCCCAAAAC
ACAAGAAATACAGAGTAAAGCGAAAATAACTGCTTACCAATATTCTGAGAGGTAACAAATGGGATATGGGTTGAGACTGCATAAAAAACG
TACTGCTGGTTGAATATCTGAGGTAAATGATGTTCAATCAAGATGCTACTTGTATCATTTTGCCCATAAATGGATAAATAATTTTATGCA

>102629_102629_4_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000361321_ORC4_chr2_148716435_ENST00000392857_length(amino acids)=356AA_BP=
MKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQ
TLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDR
SVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVY

--------------------------------------------------------------
>102629_102629_5_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000361321_ORC4_chr2_148716435_ENST00000392858_length(transcript)=2777nt_BP=344nt
GAGAACAGTGGTGCACTGTTTCCGCTGCCCTCGTTTGTCTAATTGGCCCAGACGCTCCACCAGCGCGAAGCTTCCCGGGAGCTCCTCGCT
GGCCACCCCCGCGGCCCGCAGCCCGGCAGAGGCGGGAAAGCAGCGCGCCTGCGCCGTGGGAACCGGGGCTGGAGGCGAAAAGCGGGGAGC
GGAGGGGGGCCGCTGGAGCCGAGTAGCGTACAGAGCGGCGTGTGACGCGGGGACGCCGCGTGCTCCCAACGTCGCCCCGGTTTGACGCAC
ACGGCACCAAACTGTTTGATTTAATTTTGGATGAGATCGTTCTTGCAGCAAGATGTTAATAAGACAAAATCTAGTTAATAAATCATGCTT
TGAAAGAACTCATGGAAATAGAAGAAGTGAGTGAAAATGTATTACAAGTTCACTTAAATGGACTGCTGCAGATCAATGACAAAATCGCCC
TAAAGGAAATCACAAGGCAGTTAAATCTGGAAAATGTAGTTGGAGATAAAGTTTTTGGAAGCTTTGCTGAAAACCTTTCATTTCTTCTGG
AAGCTTTAAAAAAAGGTGACCGAACTAGCAGTTGCCCAGTGATCTTCATATTAGATGAATTTGATCTTTTTGCTCATCATAAAAACCAAA
CACTTCTCTATAATCTTTTTGACATTTCTCAGTCTGCACAGACCCCAATAGCAGTTATTGGTCTTACATGTAGATTGGATATTTTGGAAC
TCTTAGAAAAAAGAGTGAAGTCAAGATTTTCTCACCGGCAGATACACTTAATGAATTCATTTGGTTTTCCACAGTATGTTAAAATATTTA
AAGAACAGTTATCTCTACCTGCAGAGTTTCCAGACAAGGTTTTTGCTGAGAAGTGGAATGAAAATGTTCAGTATCTCTCAGAAGATAGAA
GTGTGCAAGAAGTACTACAGAAGCATTTCAATATCAGCAAAAACCTGCGGTCATTACACATGCTATTGATGCTTGCTTTAAATCGAGTAA
CAGCATCGCACCCATTTATGACTGCCGTAGATCTAATGGAAGCAAGCCAACTGTGTAGCATGGACTCGAAAGCAAATATTGTACATGGTC
TATCAGTCTTGGAAATCTGTCTTATAATAGCAATGAAACATTTAAATGACATCTATGAGGAAGAGCCATTTAATTTTCAAATGGTCTATA
ATGAGTTTCAGAAGTTTGTTCAAAGGAAAGCACATTCCGTTTATAATTTTGAAAAACCTGTTGTCATGAAGGCTTTTGAACACTTGCAGC
AATTAGAATTAATAAAGCCCATGGAAAGAACTTCAGGAAATTCACAGAGAGAGTACCAGCTGATGAAACTGCTTTTGGATAATACTCAAA
TTATGAATGCTCTGCAGAAATATCCCAACTGTCCTACAGATGTGAGGCAGTGGGCAACATCCTCACTAAGCTGGTTATGAATATAACCAG
TGACTTCAACTTTGGCATTTCATTCATACTTCTGTAGAGAACGGAAAACTATTGTCCATTAACATGATATGCTAAACATTCTATAAACAT
TCTTGTATTTATGTGAGACTTGCCCATCTACTGTCTTGGCTGTGTCTTGCCTTTTAATCATGAACAGTTACATGATTTATAATTTCACTG
ATTGAGATTACTTTGTAAGTAGCTGTTCAGAAGAATAAAATATGACTGTTTTAGGGACTAGACCATGTGCTTTTTTAACACTTATATATA
TAATGGTCTATTTGAAGAGCTCACTTCAACCTAACAGCTAGATGTCTTTACAAACCTTAAACCAAAGGAGTAAAAAAAACAATGGTAAGC
ACTGAAGTATAATAAGTAACCTTTGGTACAGCAGGTTTGCTGCAGTGTTTTTTTCTGTCCACATGCAAATTTTGGATTCTATCCCAGACC
CAGGTTTTCTAGTTCAGAAGACTAACCAGCTTAGTCAGAAGATGGTTCCATGGAAGAAAAAGGCCAAGGAGTTTGAAGATTTTTCTTCTA
GACATCTCAAAATGTGGTACTCATACCATCCACATCAGAATCCCTTGTAGGATTTTCTAAAATTACAGATTGTTGAGCCTACCATAGGTC
AAAAGGACTGGAATTTTCCTTCTTAACAAGTATAGTCATGGCACCACGTAACATTTTGGTCAATGACATTGTATAAAGGGTGGTCTCATA
AGATTATACCATATTTTTACTGTACCTTTTCTATGTCTAAATATACAAATGTTTTACCATTGTGTTACAGTTGCCTACAGTATGATTACA
GTAACATTCTGTACAGTGCTATAGCTGAAGAGTAATAGGCTAGGCTATCTGTATAGCCTAAGTGTGTAACAGGCTATATACATATCATCA
GGGTCTGTGTAAGTATACTCTGTGATGTTCATACAGTGATGAAATCACCCAAAGACACATTTCTCAGAACGTAGCCCCATCATGAAGTGA
CGTGACTACCAGAGATTTCTGGAAAAGCACTCCCAAAAGTAATGAGATGTGTATGGCAATGTTAACTGAACCTGTTTGTATTAAAAAGTA
AATCCCTATGAGGAATGTGGAAATGTCCGTCAAAGCATTGTCTTTTAAGTAAGTTCCAAGATCCATGAATTAACAGAGGCATATATTTAA
AATGAAATTTAATGAGCACTTAGTGACTTCATTTGTTCAAGAATATTTGATTTCCTATTGTGTGCATGGGAGGTTTACAAAAGACAGACT

>102629_102629_5_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000361321_ORC4_chr2_148716435_ENST00000392858_length(amino acids)=356AA_BP=
MKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQ
TLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDR
SVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVY

--------------------------------------------------------------
>102629_102629_6_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000361321_ORC4_chr2_148716435_ENST00000535373_length(transcript)=2777nt_BP=344nt
GAGAACAGTGGTGCACTGTTTCCGCTGCCCTCGTTTGTCTAATTGGCCCAGACGCTCCACCAGCGCGAAGCTTCCCGGGAGCTCCTCGCT
GGCCACCCCCGCGGCCCGCAGCCCGGCAGAGGCGGGAAAGCAGCGCGCCTGCGCCGTGGGAACCGGGGCTGGAGGCGAAAAGCGGGGAGC
GGAGGGGGGCCGCTGGAGCCGAGTAGCGTACAGAGCGGCGTGTGACGCGGGGACGCCGCGTGCTCCCAACGTCGCCCCGGTTTGACGCAC
ACGGCACCAAACTGTTTGATTTAATTTTGGATGAGATCGTTCTTGCAGCAAGATGTTAATAAGACAAAATCTAGTTAATAAATCATGCTT
TGAAAGAACTCATGGAAATAGAAGAAGTGAGTGAAAATGTATTACAAGTTCACTTAAATGGACTGCTGCAGATCAATGACAAAATCGCCC
TAAAGGAAATCACAAGGCAGTTAAATCTGGAAAATGTAGTTGGAGATAAAGTTTTTGGAAGCTTTGCTGAAAACCTTTCATTTCTTCTGG
AAGCTTTAAAAAAAGGTGACCGAACTAGCAGTTGCCCAGTGATCTTCATATTAGATGAATTTGATCTTTTTGCTCATCATAAAAACCAAA
CACTTCTCTATAATCTTTTTGACATTTCTCAGTCTGCACAGACCCCAATAGCAGTTATTGGTCTTACATGTAGATTGGATATTTTGGAAC
TCTTAGAAAAAAGAGTGAAGTCAAGATTTTCTCACCGGCAGATACACTTAATGAATTCATTTGGTTTTCCACAGTATGTTAAAATATTTA
AAGAACAGTTATCTCTACCTGCAGAGTTTCCAGACAAGGTTTTTGCTGAGAAGTGGAATGAAAATGTTCAGTATCTCTCAGAAGATAGAA
GTGTGCAAGAAGTACTACAGAAGCATTTCAATATCAGCAAAAACCTGCGGTCATTACACATGCTATTGATGCTTGCTTTAAATCGAGTAA
CAGCATCGCACCCATTTATGACTGCCGTAGATCTAATGGAAGCAAGCCAACTGTGTAGCATGGACTCGAAAGCAAATATTGTACATGGTC
TATCAGTCTTGGAAATCTGTCTTATAATAGCAATGAAACATTTAAATGACATCTATGAGGAAGAGCCATTTAATTTTCAAATGGTCTATA
ATGAGTTTCAGAAGTTTGTTCAAAGGAAAGCACATTCCGTTTATAATTTTGAAAAACCTGTTGTCATGAAGGCTTTTGAACACTTGCAGC
AATTAGAATTAATAAAGCCCATGGAAAGAACTTCAGGAAATTCACAGAGAGAGTACCAGCTGATGAAACTGCTTTTGGATAATACTCAAA
TTATGAATGCTCTGCAGAAATATCCCAACTGTCCTACAGATGTGAGGCAGTGGGCAACATCCTCACTAAGCTGGTTATGAATATAACCAG
TGACTTCAACTTTGGCATTTCATTCATACTTCTGTAGAGAACGGAAAACTATTGTCCATTAACATGATATGCTAAACATTCTATAAACAT
TCTTGTATTTATGTGAGACTTGCCCATCTACTGTCTTGGCTGTGTCTTGCCTTTTAATCATGAACAGTTACATGATTTATAATTTCACTG
ATTGAGATTACTTTGTAAGTAGCTGTTCAGAAGAATAAAATATGACTGTTTTAGGGACTAGACCATGTGCTTTTTTAACACTTATATATA
TAATGGTCTATTTGAAGAGCTCACTTCAACCTAACAGCTAGATGTCTTTACAAACCTTAAACCAAAGGAGTAAAAAAAACAATGGTAAGC
ACTGAAGTATAATAAGTAACCTTTGGTACAGCAGGTTTGCTGCAGTGTTTTTTTCTGTCCACATGCAAATTTTGGATTCTATCCCAGACC
CAGGTTTTCTAGTTCAGAAGACTAACCAGCTTAGTCAGAAGATGGTTCCATGGAAGAAAAAGGCCAAGGAGTTTGAAGATTTTTCTTCTA
GACATCTCAAAATGTGGTACTCATACCATCCACATCAGAATCCCTTGTAGGATTTTCTAAAATTACAGATTGTTGAGCCTACCATAGGTC
AAAAGGACTGGAATTTTCCTTCTTAACAAGTATAGTCATGGCACCACGTAACATTTTGGTCAATGACATTGTATAAAGGGTGGTCTCATA
AGATTATACCATATTTTTACTGTACCTTTTCTATGTCTAAATATACAAATGTTTTACCATTGTGTTACAGTTGCCTACAGTATGATTACA
GTAACATTCTGTACAGTGCTATAGCTGAAGAGTAATAGGCTAGGCTATCTGTATAGCCTAAGTGTGTAACAGGCTATATACATATCATCA
GGGTCTGTGTAAGTATACTCTGTGATGTTCATACAGTGATGAAATCACCCAAAGACACATTTCTCAGAACGTAGCCCCATCATGAAGTGA
CGTGACTACCAGAGATTTCTGGAAAAGCACTCCCAAAAGTAATGAGATGTGTATGGCAATGTTAACTGAACCTGTTTGTATTAAAAAGTA
AATCCCTATGAGGAATGTGGAAATGTCCGTCAAAGCATTGTCTTTTAAGTAAGTTCCAAGATCCATGAATTAACAGAGGCATATATTTAA
AATGAAATTTAATGAGCACTTAGTGACTTCATTTGTTCAAGAATATTTGATTTCCTATTGTGTGCATGGGAGGTTTACAAAAGACAGACT

>102629_102629_6_ZNF644-ORC4_ZNF644_chr1_91447866_ENST00000361321_ORC4_chr2_148716435_ENST00000535373_length(amino acids)=356AA_BP=
MKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQ
TLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDR
SVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVY

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Fusion Gene PPI Analysis for ZNF644-ORC4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF644-ORC4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF644-ORC4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource