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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF763-RAD23A (FusionGDB2 ID:102879)

Fusion Gene Summary for ZNF763-RAD23A

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF763-RAD23A
Fusion gene ID: 102879
HgeneTgene
Gene symbol

ZNF763

RAD23A

Gene ID

284390

5886

Gene namezinc finger protein 763RAD23 homolog A, nucleotide excision repair protein
SynonymsZNF|ZNF440LHHR23A|HR23A
Cytomap

19p13.2

19p13.13

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 763DNA-binding proteinzinc finger protein 440 likeUV excision repair protein RAD23 homolog ARAD23, yeast homolog, A
Modification date2020031320200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000538752, ENST00000590798, 
ENST00000591944, ENST00000343949, 
ENST00000358987, ENST00000545530, 
ENST00000592625, 		ENST00000588826, 
ENST00000592268, ENST00000316856, 
ENST00000541222, ENST00000586534, 
Fusion gene scores* DoF score4 X 2 X 4=3213 X 9 X 9=1053
# samples 415
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(15/1053*10)=-2.81147103052984
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF763 [Title/Abstract] AND RAD23A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF763(12036088)-RAD23A(13063503), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRAD23A

GO:0006289

nucleotide-excision repair

9372924

TgeneRAD23A

GO:0032434

regulation of proteasomal ubiquitin-dependent protein catabolic process

12643283


check buttonFusion gene breakpoints across ZNF763 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RAD23A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-HS-A5N9-01AZNF763chr19

12036088

-RAD23Achr19

13063503

+
ChimerDB4SARCTCGA-HS-A5N9-01AZNF763chr19

12036088

+RAD23Achr19

13063503

+


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Fusion Gene ORF analysis for ZNF763-RAD23A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000538752ENST00000588826ZNF763chr19

12036088

+RAD23Achr19

13063503

+
5CDS-intronENST00000538752ENST00000592268ZNF763chr19

12036088

+RAD23Achr19

13063503

+
5CDS-intronENST00000590798ENST00000588826ZNF763chr19

12036088

+RAD23Achr19

13063503

+
5CDS-intronENST00000590798ENST00000592268ZNF763chr19

12036088

+RAD23Achr19

13063503

+
5CDS-intronENST00000591944ENST00000588826ZNF763chr19

12036088

+RAD23Achr19

13063503

+
5CDS-intronENST00000591944ENST00000592268ZNF763chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000538752ENST00000316856ZNF763chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000538752ENST00000541222ZNF763chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000538752ENST00000586534ZNF763chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000590798ENST00000316856ZNF763chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000590798ENST00000541222ZNF763chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000590798ENST00000586534ZNF763chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000591944ENST00000316856ZNF763chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000591944ENST00000541222ZNF763chr19

12036088

+RAD23Achr19

13063503

+
In-frameENST00000591944ENST00000586534ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000343949ENST00000316856ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000343949ENST00000541222ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000343949ENST00000586534ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000358987ENST00000316856ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000358987ENST00000541222ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000358987ENST00000586534ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000545530ENST00000316856ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000545530ENST00000541222ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000545530ENST00000586534ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000592625ENST00000316856ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000592625ENST00000541222ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-3CDSENST00000592625ENST00000586534ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-intronENST00000343949ENST00000588826ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-intronENST00000343949ENST00000592268ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-intronENST00000358987ENST00000588826ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-intronENST00000358987ENST00000592268ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-intronENST00000545530ENST00000588826ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-intronENST00000545530ENST00000592268ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-intronENST00000592625ENST00000588826ZNF763chr19

12036088

+RAD23Achr19

13063503

+
intron-intronENST00000592625ENST00000592268ZNF763chr19

12036088

+RAD23Achr19

13063503

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000590798ZNF763chr1912036088+ENST00000541222RAD23Achr1913063503+69819946477143
ENST00000590798ZNF763chr1912036088+ENST00000316856RAD23Achr1913063503+1052199838395147
ENST00000590798ZNF763chr1912036088+ENST00000586534RAD23Achr1913063503+1071199838395147
ENST00000538752ZNF763chr1912036088+ENST00000541222RAD23Achr1913063503+69819946477143
ENST00000538752ZNF763chr1912036088+ENST00000316856RAD23Achr1913063503+1052199838395147
ENST00000538752ZNF763chr1912036088+ENST00000586534RAD23Achr1913063503+1071199838395147
ENST00000591944ZNF763chr1912036088+ENST00000541222RAD23Achr1913063503+66216310441143
ENST00000591944ZNF763chr1912036088+ENST00000316856RAD23Achr1913063503+1016163802359147
ENST00000591944ZNF763chr1912036088+ENST00000586534RAD23Achr1913063503+1035163802359147

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000590798ENST00000541222ZNF763chr1912036088+RAD23Achr1913063503+0.03506430.9649357
ENST00000590798ENST00000316856ZNF763chr1912036088+RAD23Achr1913063503+0.72796790.27203205
ENST00000590798ENST00000586534ZNF763chr1912036088+RAD23Achr1913063503+0.766963840.23303613
ENST00000538752ENST00000541222ZNF763chr1912036088+RAD23Achr1913063503+0.03506430.9649357
ENST00000538752ENST00000316856ZNF763chr1912036088+RAD23Achr1913063503+0.72796790.27203205
ENST00000538752ENST00000586534ZNF763chr1912036088+RAD23Achr1913063503+0.766963840.23303613
ENST00000591944ENST00000541222ZNF763chr1912036088+RAD23Achr1913063503+0.0359791220.9640209
ENST00000591944ENST00000316856ZNF763chr1912036088+RAD23Achr1913063503+0.68272530.31727463
ENST00000591944ENST00000586534ZNF763chr1912036088+RAD23Achr1913063503+0.71944120.28055882

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Fusion Genomic Features for ZNF763-RAD23A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNF763chr1912036088+RAD23Achr1913063502+1.04E-151
ZNF763chr1912036088+RAD23Achr1913063502+1.04E-151

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZNF763-RAD23A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:12036088/chr19:13063503)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRAD23Achr19:12036088chr19:13063503ENST0000058653469318_358271364.0DomainUBA 2
TgeneRAD23Achr19:12036088chr19:13063503ENST0000059226808161_2010309.0DomainUBA 1
TgeneRAD23Achr19:12036088chr19:13063503ENST00000592268081_810309.0DomainUbiquitin-like
TgeneRAD23Achr19:12036088chr19:13063503ENST0000059226808318_3580309.0DomainUBA 2
TgeneRAD23Achr19:12036088chr19:13063503ENST0000058653469319_363271364.0RegionNote=HIV-1 vpr binding
TgeneRAD23Achr19:12036088chr19:13063503ENST0000059226808319_3630309.0RegionNote=HIV-1 vpr binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF763chr19:12036088chr19:13063503ENST00000343949+144_860398.0DomainKRAB
HgeneZNF763chr19:12036088chr19:13063503ENST00000358987+144_860395.0DomainKRAB
HgeneZNF763chr19:12036088chr19:13063503ENST00000343949+14144_1660398.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF763chr19:12036088chr19:13063503ENST00000343949+14172_1940398.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF763chr19:12036088chr19:13063503ENST00000343949+14200_2220398.0Zinc fingerC2H2-type 3
HgeneZNF763chr19:12036088chr19:13063503ENST00000343949+14228_2500398.0Zinc fingerC2H2-type 4
HgeneZNF763chr19:12036088chr19:13063503ENST00000343949+14256_2780398.0Zinc fingerC2H2-type 5
HgeneZNF763chr19:12036088chr19:13063503ENST00000343949+14284_3060398.0Zinc fingerC2H2-type 6
HgeneZNF763chr19:12036088chr19:13063503ENST00000343949+14312_3340398.0Zinc fingerC2H2-type 7
HgeneZNF763chr19:12036088chr19:13063503ENST00000343949+14340_3620398.0Zinc fingerC2H2-type 8
HgeneZNF763chr19:12036088chr19:13063503ENST00000358987+14144_1660395.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF763chr19:12036088chr19:13063503ENST00000358987+14172_1940395.0Zinc fingerC2H2-type 2%3B degenerate
HgeneZNF763chr19:12036088chr19:13063503ENST00000358987+14200_2220395.0Zinc fingerC2H2-type 3
HgeneZNF763chr19:12036088chr19:13063503ENST00000358987+14228_2500395.0Zinc fingerC2H2-type 4
HgeneZNF763chr19:12036088chr19:13063503ENST00000358987+14256_2780395.0Zinc fingerC2H2-type 5
HgeneZNF763chr19:12036088chr19:13063503ENST00000358987+14284_3060395.0Zinc fingerC2H2-type 6
HgeneZNF763chr19:12036088chr19:13063503ENST00000358987+14312_3340395.0Zinc fingerC2H2-type 7
HgeneZNF763chr19:12036088chr19:13063503ENST00000358987+14340_3620395.0Zinc fingerC2H2-type 8
TgeneRAD23Achr19:12036088chr19:13063503ENST0000058653469161_201271364.0DomainUBA 1
TgeneRAD23Achr19:12036088chr19:13063503ENST00000586534691_81271364.0DomainUbiquitin-like


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Fusion Gene Sequence for ZNF763-RAD23A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102879_102879_1_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000538752_RAD23A_chr19_13063503_ENST00000316856_length(transcript)=1052nt_BP=199nt
ACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCCCGAGAGG
GACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACCCCGGTAC
ATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGGACATCTC
AGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAGCTATAGA
GAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCAACTTCCT
CCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTTTATAAAA
GAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGCTTCCTGT
CCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCCAGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGAAGCTGGC
AGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCTCTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCTCCATCCT
CCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTCTAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGTGGCCCAA
ATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAGGCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAACATCAGC

>102879_102879_1_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000538752_RAD23A_chr19_13063503_ENST00000316856_length(amino acids)=147AA_BP=
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------
>102879_102879_2_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000538752_RAD23A_chr19_13063503_ENST00000541222_length(transcript)=698nt_BP=199nt
ACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCCCGAGAGG
GACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACCCCGGTAC
ATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGGACATCTC
AGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAGCTATAGA
GAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCAACTTCCT
CCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTTTATAAAA
GAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGCTTCCTGT

>102879_102879_2_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000538752_RAD23A_chr19_13063503_ENST00000541222_length(amino acids)=143AA_BP=51
MRGRRLVTGQTSPRGTWCLYPGFCRSVACAMPCCSHRSCREDPGTSESREMQISRHQEQFIQMLNEPPGELADISDVEGEVGAIGEEAPQ

--------------------------------------------------------------
>102879_102879_3_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000538752_RAD23A_chr19_13063503_ENST00000586534_length(transcript)=1071nt_BP=199nt
ACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCCCGAGAGG
GACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACCCCGGTAC
ATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGGACATCTC
AGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAGCTATAGA
GAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCAACTTCCT
CCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTTTATAAAA
GAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGCTTCCTGT
CCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCCAGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGAAGCTGGC
AGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCTCTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCTCCATCCT
CCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTCTAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGTGGCCCAA
ATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAGGCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAACATCAGC

>102879_102879_3_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000538752_RAD23A_chr19_13063503_ENST00000586534_length(amino acids)=147AA_BP=
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------
>102879_102879_4_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000590798_RAD23A_chr19_13063503_ENST00000316856_length(transcript)=1052nt_BP=199nt
ACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCCCGAGAGG
GACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACCCCGGTAC
ATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGGACATCTC
AGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAGCTATAGA
GAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCAACTTCCT
CCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTTTATAAAA
GAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGCTTCCTGT
CCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCCAGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGAAGCTGGC
AGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCTCTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCTCCATCCT
CCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTCTAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGTGGCCCAA
ATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAGGCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAACATCAGC

>102879_102879_4_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000590798_RAD23A_chr19_13063503_ENST00000316856_length(amino acids)=147AA_BP=
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------
>102879_102879_5_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000590798_RAD23A_chr19_13063503_ENST00000541222_length(transcript)=698nt_BP=199nt
ACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCCCGAGAGG
GACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACCCCGGTAC
ATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGGACATCTC
AGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAGCTATAGA
GAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCAACTTCCT
CCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTTTATAAAA
GAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGCTTCCTGT

>102879_102879_5_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000590798_RAD23A_chr19_13063503_ENST00000541222_length(amino acids)=143AA_BP=51
MRGRRLVTGQTSPRGTWCLYPGFCRSVACAMPCCSHRSCREDPGTSESREMQISRHQEQFIQMLNEPPGELADISDVEGEVGAIGEEAPQ

--------------------------------------------------------------
>102879_102879_6_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000590798_RAD23A_chr19_13063503_ENST00000586534_length(transcript)=1071nt_BP=199nt
ACAGTTCATCCGGAAATGGAGGGGGTCGCTTTCCTCACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCCCGAGAGG
GACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGTCGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACCCCGGTAC
ATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCAGGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGGACATCTC
AGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGAGGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAGCTATAGA
GAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGTCATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCAACTTCCT
CCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGAAGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTTTATAAAA
GAAAAAATATATATATATTCATGTTTATTTAAGAAATGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGCTTCCTGT
CCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCCAGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGAAGCTGGC
AGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCTCTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCTCCATCCT
CCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTCTAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGTGGCCCAA
ATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAGGCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAACATCAGC

>102879_102879_6_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000590798_RAD23A_chr19_13063503_ENST00000586534_length(amino acids)=147AA_BP=
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------
>102879_102879_7_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000591944_RAD23A_chr19_13063503_ENST00000316856_length(transcript)=1016nt_BP=163nt
ACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCCCGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGT
CGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACCCCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCA
GGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGGACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGA
GGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAGCTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGT
CATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCAACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGA
AGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTTTATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAA
TGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGCTTCCTGTCCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCC
AGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGAAGCTGGCAGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCT
CTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCTCCATCCTCCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTC
TAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGTGGCCCAAATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAG
GCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAACATCAGCTCATTGTCAAGGCCACCCCCACCCCAGAACAGAACC

>102879_102879_7_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000591944_RAD23A_chr19_13063503_ENST00000316856_length(amino acids)=147AA_BP=
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------
>102879_102879_8_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000591944_RAD23A_chr19_13063503_ENST00000541222_length(transcript)=662nt_BP=163nt
ACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCCCGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGT
CGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACCCCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCA
GGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGGACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGA
GGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAGCTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGT
CATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCAACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGA
AGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTTTATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAA
TGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGCTTCCTGTCCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCC

>102879_102879_8_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000591944_RAD23A_chr19_13063503_ENST00000541222_length(amino acids)=143AA_BP=51
MRGRRLVTGQTSPRGTWCLYPGFCRSVACAMPCCSHRSCREDPGTSESREMQISRHQEQFIQMLNEPPGELADISDVEGEVGAIGEEAPQ

--------------------------------------------------------------
>102879_102879_9_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000591944_RAD23A_chr19_13063503_ENST00000586534_length(transcript)=1035nt_BP=163nt
ACCTTCCTCGCTGCGCGGGCGGCGGTTGGTAACCGGTCAGACCAGCCCGAGAGGGACCTGGTGCCTGTACCCAGGCTTCTGTCGCTCTGT
CGCCTGCGCTATGCCCTGCTGTAGTCACAGGAGCTGTAGAGAGGACCCCGGTACATCTGAAAGCCGGGAAATGCAAATCAGCCGGCACCA
GGAGCAGTTCATCCAGATGCTGAACGAGCCCCCTGGGGAGCTGGCGGACATCTCAGATGTGGAGGGGGAGGTGGGCGCCATAGGAGAGGA
GGCCCCGCAGATGAACTACATCCAGGTGACGCCGCAGGAGAAAGAAGCTATAGAGAGGTTGAAGGCCCTGGGCTTCCCAGAGAGCCTGGT
CATCCAGGCCTATTTCGCGTGTGAAAAAAATGAGAACTTGGCTGCCAACTTCCTCCTGAGTCAGAACTTTGATGACGAGTGATGCCAGGA
AGCCAGGCCACCGAAGCCCCCACCCTACCCTTATTCCATGAAAGTTTTATAAAAGAAAAAATATATATATATTCATGTTTATTTAAGAAA
TGGAAAAAAAAATCAAAAATCTTAAAAAAACAAGCAAACAGTCCAGCTTCCTGTCCTCCTAAAGTGGCCCCTGTTCCCATCTCCCGGGCC
AGACAGCTGTCCCCCCGTCCTCCTCCCCAGCCCAGCCTGCTCAGAGAAGCTGGCAGGACTGGGAGGCGACAGATGGGCCCCTCTTGGCCT
CTGTCCCAGCTCTCTGCAGCCAGACGGAAAGGCGGCTGCTTGCCTCTCCATCCTCCGAAAAACCCCTGAGGACCCCCCCCCATCCTCTTC
TAGGATGAGGGGAAGCTGGAGCCCCAACTTTGATCCTCCATTGGAGTGGCCCAAATCTTTCCATCTAGGGCAAGTCCTGAAAGGCCCAAG
GCCCCCTCCCCAGTCTGGCCTTGGCCTCCAGCCTGGAGAAGGGCTAACATCAGCTCATTGTCAAGGCCACCCCCACCCCAGAACAGAACC

>102879_102879_9_ZNF763-RAD23A_ZNF763_chr19_12036088_ENST00000591944_RAD23A_chr19_13063503_ENST00000586534_length(amino acids)=147AA_BP=
MGGGPQGFFGGWRGKQPPFRLAAESWDRGQEGPICRLPVLPASLSRLGWGGGRGDSCLAREMGTGATLGGQEAGLFACFFKIFDFFFHFL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNF763-RAD23A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF763-RAD23A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF763-RAD23A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource