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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF773-PPP2R1A (FusionGDB2 ID:102900)

Fusion Gene Summary for ZNF773-PPP2R1A

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF773-PPP2R1A
Fusion gene ID: 102900
HgeneTgene
Gene symbol

ZNF773

PPP2R1A

Gene ID

374928

5518

Gene namezinc finger protein 773protein phosphatase 2 scaffold subunit Aalpha
SynonymsZNF419BMRD36|PP2A-Aalpha|PP2AA|PP2AAALPHA|PR65A
Cytomap

19q13.43

19q13.41

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 773zinc finger protein 419Bserine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoformPP2A subunit A isoform PR65-alphaPP2A subunit A isoform R1-alphamedium tumor antigen-associated 61 KDA proteinprotein phosphatase 2 (formerly 2A), regulatory subunit A (P
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000282292, ENST00000593916, 
ENST00000598770, ENST00000599847, 
ENST00000473455, ENST00000462990, 
ENST00000477989, ENST00000444322, 
ENST00000322088, 
Fusion gene scores* DoF score2 X 3 X 2=1210 X 12 X 4=480
# samples 212
** MAII scorelog2(2/12*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(12/480*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF773 [Title/Abstract] AND PPP2R1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF773(58011481)-PPP2R1A(52705197), # samples:2
Anticipated loss of major functional domain due to fusion event.ZNF773-PPP2R1A seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
ZNF773-PPP2R1A seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ZNF773-PPP2R1A seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
ZNF773-PPP2R1A seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePPP2R1A

GO:0007059

chromosome segregation

16580887


check buttonFusion gene breakpoints across ZNF773 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PPP2R1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-OL-A5RV-01AZNF773chr19

58011481

+PPP2R1Achr19

52705197

+


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Fusion Gene ORF analysis for ZNF773-PPP2R1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000282292ENST00000473455ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
5CDS-3UTRENST00000593916ENST00000473455ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
5CDS-3UTRENST00000598770ENST00000473455ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
5CDS-3UTRENST00000599847ENST00000473455ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
5CDS-5UTRENST00000282292ENST00000462990ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
5CDS-5UTRENST00000593916ENST00000462990ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
5CDS-5UTRENST00000598770ENST00000462990ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
5CDS-5UTRENST00000599847ENST00000462990ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
5CDS-intronENST00000282292ENST00000477989ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
5CDS-intronENST00000593916ENST00000477989ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
5CDS-intronENST00000598770ENST00000477989ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
5CDS-intronENST00000599847ENST00000477989ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
Frame-shiftENST00000282292ENST00000444322ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
Frame-shiftENST00000593916ENST00000444322ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
Frame-shiftENST00000598770ENST00000444322ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
Frame-shiftENST00000599847ENST00000444322ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
In-frameENST00000282292ENST00000322088ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
In-frameENST00000593916ENST00000322088ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
In-frameENST00000598770ENST00000322088ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+
In-frameENST00000599847ENST00000322088ZNF773chr19

58011481

+PPP2R1Achr19

52705197

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000593916ZNF773chr1958011481+ENST00000322088PPP2R1Achr1952705197+33441991661890574
ENST00000598770ZNF773chr1958011481+ENST00000322088PPP2R1Achr1952705197+33241791461870574
ENST00000599847ZNF773chr1958011481+ENST00000322088PPP2R1Achr1952705197+33201751421866574
ENST00000282292ZNF773chr1958011481+ENST00000322088PPP2R1Achr1952705197+33181731401864574

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000593916ENST00000322088ZNF773chr1958011481+PPP2R1Achr1952705197+0.0014182990.99858177
ENST00000598770ENST00000322088ZNF773chr1958011481+PPP2R1Achr1952705197+0.0013516270.99864835
ENST00000599847ENST00000322088ZNF773chr1958011481+PPP2R1Achr1952705197+0.0013737290.99862623
ENST00000282292ENST00000322088ZNF773chr1958011481+PPP2R1Achr1952705197+0.0013701070.9986299

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Fusion Genomic Features for ZNF773-PPP2R1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNF773chr1958011481+PPP2R1Achr1952705196+3.69E-060.9999963
ZNF773chr1958011481+PPP2R1Achr1952705196+3.69E-060.9999963

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZNF773-PPP2R1A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:58011481/chr19:52705197)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015400_58926590.0RegionNote=PP2A subunit C binding
TgenePPP2R1Achr19:58011481chr19:52705197ENST0000032208801547_32126590.0RegionNote=Polyoma small and medium T antigens Binding
TgenePPP2R1Achr19:58011481chr19:52705197ENST0000032208801585_23926590.0RegionNote=SV40 small T antigen binding
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015124_16126590.0RepeatNote=HEAT 4
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015162_20026590.0RepeatNote=HEAT 5
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015201_23926590.0RepeatNote=HEAT 6
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015240_27826590.0RepeatNote=HEAT 7
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015279_32126590.0RepeatNote=HEAT 8
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015322_36026590.0RepeatNote=HEAT 9
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015361_39926590.0RepeatNote=HEAT 10
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015400_43826590.0RepeatNote=HEAT 11
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015439_47726590.0RepeatNote=HEAT 12
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015478_51626590.0RepeatNote=HEAT 13
TgenePPP2R1Achr19:58011481chr19:52705197ENST0000032208801547_8426590.0RepeatNote=HEAT 2
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015517_55526590.0RepeatNote=HEAT 14
TgenePPP2R1Achr19:58011481chr19:52705197ENST00000322088015556_58926590.0RepeatNote=HEAT 15
TgenePPP2R1Achr19:58011481chr19:52705197ENST0000032208801585_12326590.0RepeatNote=HEAT 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF773chr19:58011481chr19:52705197ENST00000282292+1415_8611443.0DomainKRAB
HgeneZNF773chr19:58011481chr19:52705197ENST00000598770+1415_8611442.0DomainKRAB
HgeneZNF773chr19:58011481chr19:52705197ENST00000282292+14191_21311443.0Zinc fingerC2H2-type 1
HgeneZNF773chr19:58011481chr19:52705197ENST00000282292+14219_24111443.0Zinc fingerC2H2-type 2
HgeneZNF773chr19:58011481chr19:52705197ENST00000282292+14247_26911443.0Zinc fingerC2H2-type 3
HgeneZNF773chr19:58011481chr19:52705197ENST00000282292+14275_29711443.0Zinc fingerC2H2-type 4
HgeneZNF773chr19:58011481chr19:52705197ENST00000282292+14303_32511443.0Zinc fingerC2H2-type 5
HgeneZNF773chr19:58011481chr19:52705197ENST00000282292+14331_35311443.0Zinc fingerC2H2-type 6
HgeneZNF773chr19:58011481chr19:52705197ENST00000282292+14359_38111443.0Zinc fingerC2H2-type 7
HgeneZNF773chr19:58011481chr19:52705197ENST00000282292+14387_40911443.0Zinc fingerC2H2-type 8
HgeneZNF773chr19:58011481chr19:52705197ENST00000282292+14415_43711443.0Zinc fingerC2H2-type 9
HgeneZNF773chr19:58011481chr19:52705197ENST00000598770+14191_21311442.0Zinc fingerC2H2-type 1
HgeneZNF773chr19:58011481chr19:52705197ENST00000598770+14219_24111442.0Zinc fingerC2H2-type 2
HgeneZNF773chr19:58011481chr19:52705197ENST00000598770+14247_26911442.0Zinc fingerC2H2-type 3
HgeneZNF773chr19:58011481chr19:52705197ENST00000598770+14275_29711442.0Zinc fingerC2H2-type 4
HgeneZNF773chr19:58011481chr19:52705197ENST00000598770+14303_32511442.0Zinc fingerC2H2-type 5
HgeneZNF773chr19:58011481chr19:52705197ENST00000598770+14331_35311442.0Zinc fingerC2H2-type 6
HgeneZNF773chr19:58011481chr19:52705197ENST00000598770+14359_38111442.0Zinc fingerC2H2-type 7
HgeneZNF773chr19:58011481chr19:52705197ENST00000598770+14387_40911442.0Zinc fingerC2H2-type 8
HgeneZNF773chr19:58011481chr19:52705197ENST00000598770+14415_43711442.0Zinc fingerC2H2-type 9
TgenePPP2R1Achr19:58011481chr19:52705197ENST000003220880158_39926590.0RegionNote=PP2A subunit B binding
TgenePPP2R1Achr19:58011481chr19:52705197ENST000003220880158_4626590.0RepeatNote=HEAT 1


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Fusion Gene Sequence for ZNF773-PPP2R1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102900_102900_1_ZNF773-PPP2R1A_ZNF773_chr19_58011481_ENST00000282292_PPP2R1A_chr19_52705197_ENST00000322088_length(transcript)=3318nt_BP=173nt
CGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCGGGTCTGAGGCTCGGTGGCGGCGCCCA
GGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCACGCTGAGGGACCCCGCTCAGCTTCGCC
TCAACAGCATCAAGAAGCTGTCCACCATCGCCTTGGCCCTTGGGGTTGAAAGGACCCGAAGTGAGCTTCTGCCTTTCCTTACAGATACCA
TCTATGATGAAGATGAGGTCCTCCTGGCCCTGGCAGAACAGCTGGGAACCTTCACTACCCTGGTGGGAGGCCCAGAGTACGTGCACTGCC
TGCTGCCACCGCTGGAGTCGCTGGCCACAGTGGAGGAGACAGTGGTGCGGGACAAGGCAGTGGAGTCCTTACGGGCCATCTCACACGAGC
ACTCGCCCTCTGACCTGGAGGCGCACTTTGTGCCGCTAGTGAAGCGGCTGGCGGGCGGCGACTGGTTCACCTCCCGCACCTCGGCCTGCG
GCCTCTTCTCCGTCTGCTACCCCCGAGTGTCCAGTGCTGTGAAGGCGGAACTTCGACAGTACTTCCGGAACCTGTGCTCAGATGACACCC
CCATGGTGCGGCGGGCCGCAGCCTCCAAGCTGGGGGAGTTTGCCAAGGTGCTGGAGCTGGACAACGTCAAGAGTGAGATCATCCCCATGT
TCTCCAACCTGGCCTCTGACGAGCAGGACTCGGTGCGGCTGCTGGCGGTGGAGGCGTGCGTGAACATCGCCCAGCTTCTGCCCCAGGAGG
ATCTGGAGGCCCTGGTGATGCCCACTCTGCGCCAGGCCGCTGAAGACAAGTCCTGGCGCGTCCGCTACATGGTGGCTGACAAGTTCACAG
AGCTCCAGAAAGCAGTGGGGCCTGAGATCACCAAGACAGACCTGGTCCCTGCCTTCCAGAACCTGATGAAAGACTGTGAGGCCGAGGTGA
GGGCCGCAGCCTCCCACAAGGTCAAAGAGTTCTGTGAAAACCTCTCAGCTGACTGTCGGGAGAATGTGATCATGTCCCAGATCTTGCCCT
GCATCAAGGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCTGCCCTGGCCTCAGTCATCATGGGTCTCTCTCCCATCTTGGGCAAAG
ACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTGAAGGATGAGTGCCCTGAGGTACGGCTGAACATCATCTCTAACCTGG
ACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCCCTGCTCCCTGCCATTGTGGAGCTGGCTGAGGACGCCAAGTGGCGGG
TGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAGCTGGGAGTGGAGTTCTTTGATGAGAAACTTAACTCCTTGTGCATGG
CCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACCAGCAACCTGAAGAAGCTAGTGGAAAAGTTTGGGAAGGAGTGGGCCC
ATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCCAACTACCTGCACCGCATGACTACGCTCTTCTGCATCAATGTGCTGT
CTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCCACGGTTCTGCGCATGGCTGGGGACCCGGTTGCCAATGTCCGCTTCA
ATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAACAGCACCTTGCAGAGTGAAGTCAAGCCCATCCTAGAGAAGCTGACCC
AGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTGACTGTTCTGTCTCTCGCCTGATGCTGGAAGAGGAGCAAACACTGGC
CTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGAGACACTGGGGGGCCTTTGGCTGTCACTCCCTGTGCATGGTCTGACC
CCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGGGAAGATGTCTCACTGTCCACCTCCCAACGGGCTAGGGGAGCACGGG
GTTGGACAGGACAGTGACCTTGGGAGGAAGGGGCTACTCCGCCCACGTCAGGGAGAGATGTGAGCATCCCGGGTCACTGGATCCTGCTGC
TGTAATGGGAACCCCTCCCCCATTTACTTCTCCACCTCCCGTCCTCCCCATCATTGGTTTTTTTTTGTGTGTCAACTGTGCCGTTTTTAT
TTTATTCCTTTTATTTTCCCCCTTTTCACAGAGAAATAAAGGTCTAGAAGTAGTTGGTCCTCTGGCCTTAGTCATCAGCTTGGAGGAGGG
GGCACCACCCCAGAGCCACAACATCTGCGCTTTTCTCTGGAGAAGATCTTGTTACAGGACCCATTATACCCCTATGTCCCGAAAGAATAC
TCTGGGGATCCCCCCAGGAGTGCTGCTGGCCTTTGGGGTAGAGGGTCCATGAGGTGCTCTGGGTGGTGTCCTGTAGTGCAGTTCAGATTC
ATAGATGTCGGCCGAGTATTTGGGGGGTTAAGAGCAGGTGCCTTGGAACCAGACTGCCTGGGTCCAAATTGTGGCTCCTTCAGTTAATAG
ACGTGTGACTAGGAGTAGCTTGTTAAGTCTTTATGAGCTCAGTTTTGTATTGTGTAAAATGAGAGTTACAGTAATACCTAGATTGCAGGG
TGGGTGGCGAGGACCAAGTGAATTAGTACCTGGAAAGTGTGTAACAGTTTCAACATGAGAAGTACACAACATGAGAAGCAGAGTTAGCTG
TACATTGCCAGAGAACCCCCTGTGGGCCATTTCCTGTGTTCTTGAAGAAGACTTGGGCTTGGACCCTGTCCCCAGGAGGTCTCAGAGTAA
TCAGGACGGTACTAGGGAGAGAACTGTGGCAAGATAGATCAGTTATCTCGGTATCTATTCTCCCCTTCCTAATGTAGAAGCTCTGATTTT
TAACTGGGCAGATGACTACATGGATTCAAGGTATTTTCCTAGTGTCTCTTGAAATTAGGTGTGGTATTGTGACCAAATTCTAGCCAAAAA
GATGTTGAACAGAAGTGGTATATGCAGCTTCTAGGAAGTGTTCTTAAGGGGGAAGGCGTCATCCCCCACCTTTCCTCCTTCCTGCACTCT
GGAATGTGGACCAGATGGCTGGAGTAGGAGCTGCCACCTGGGGCCAGAAAATGATCTTAGGCGTGAAGGTCAAGTAAGGCAGGACAAGAG

>102900_102900_1_ZNF773-PPP2R1A_ZNF773_chr19_58011481_ENST00000282292_PPP2R1A_chr19_52705197_ENST00000322088_length(amino acids)=574AA_BP=11
MAAATLRDPAQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVR
DKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKV
LELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVP
AFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKD
ECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSN
LKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNST

--------------------------------------------------------------
>102900_102900_2_ZNF773-PPP2R1A_ZNF773_chr19_58011481_ENST00000593916_PPP2R1A_chr19_52705197_ENST00000322088_length(transcript)=3344nt_BP=199nt
ACTCAGCTTGCCGGAAGCTGGTTGTTCGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCG
GGTCTGAGGCTCGGTGGCGGCGCCCAGGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCAC
GCTGAGGGACCCCGCTCAGCTTCGCCTCAACAGCATCAAGAAGCTGTCCACCATCGCCTTGGCCCTTGGGGTTGAAAGGACCCGAAGTGA
GCTTCTGCCTTTCCTTACAGATACCATCTATGATGAAGATGAGGTCCTCCTGGCCCTGGCAGAACAGCTGGGAACCTTCACTACCCTGGT
GGGAGGCCCAGAGTACGTGCACTGCCTGCTGCCACCGCTGGAGTCGCTGGCCACAGTGGAGGAGACAGTGGTGCGGGACAAGGCAGTGGA
GTCCTTACGGGCCATCTCACACGAGCACTCGCCCTCTGACCTGGAGGCGCACTTTGTGCCGCTAGTGAAGCGGCTGGCGGGCGGCGACTG
GTTCACCTCCCGCACCTCGGCCTGCGGCCTCTTCTCCGTCTGCTACCCCCGAGTGTCCAGTGCTGTGAAGGCGGAACTTCGACAGTACTT
CCGGAACCTGTGCTCAGATGACACCCCCATGGTGCGGCGGGCCGCAGCCTCCAAGCTGGGGGAGTTTGCCAAGGTGCTGGAGCTGGACAA
CGTCAAGAGTGAGATCATCCCCATGTTCTCCAACCTGGCCTCTGACGAGCAGGACTCGGTGCGGCTGCTGGCGGTGGAGGCGTGCGTGAA
CATCGCCCAGCTTCTGCCCCAGGAGGATCTGGAGGCCCTGGTGATGCCCACTCTGCGCCAGGCCGCTGAAGACAAGTCCTGGCGCGTCCG
CTACATGGTGGCTGACAAGTTCACAGAGCTCCAGAAAGCAGTGGGGCCTGAGATCACCAAGACAGACCTGGTCCCTGCCTTCCAGAACCT
GATGAAAGACTGTGAGGCCGAGGTGAGGGCCGCAGCCTCCCACAAGGTCAAAGAGTTCTGTGAAAACCTCTCAGCTGACTGTCGGGAGAA
TGTGATCATGTCCCAGATCTTGCCCTGCATCAAGGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCTGCCCTGGCCTCAGTCATCAT
GGGTCTCTCTCCCATCTTGGGCAAAGACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTGAAGGATGAGTGCCCTGAGGT
ACGGCTGAACATCATCTCTAACCTGGACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCCCTGCTCCCTGCCATTGTGGA
GCTGGCTGAGGACGCCAAGTGGCGGGTGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAGCTGGGAGTGGAGTTCTTTGA
TGAGAAACTTAACTCCTTGTGCATGGCCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACCAGCAACCTGAAGAAGCTAGT
GGAAAAGTTTGGGAAGGAGTGGGCCCATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCCAACTACCTGCACCGCATGAC
TACGCTCTTCTGCATCAATGTGCTGTCTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCCACGGTTCTGCGCATGGCTGG
GGACCCGGTTGCCAATGTCCGCTTCAATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAACAGCACCTTGCAGAGTGAAGT
CAAGCCCATCCTAGAGAAGCTGACCCAGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTGACTGTTCTGTCTCTCGCCTG
ATGCTGGAAGAGGAGCAAACACTGGCCTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGAGACACTGGGGGGCCTTTGGC
TGTCACTCCCTGTGCATGGTCTGACCCCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGGGAAGATGTCTCACTGTCCAC
CTCCCAACGGGCTAGGGGAGCACGGGGTTGGACAGGACAGTGACCTTGGGAGGAAGGGGCTACTCCGCCCACGTCAGGGAGAGATGTGAG
CATCCCGGGTCACTGGATCCTGCTGCTGTAATGGGAACCCCTCCCCCATTTACTTCTCCACCTCCCGTCCTCCCCATCATTGGTTTTTTT
TTGTGTGTCAACTGTGCCGTTTTTATTTTATTCCTTTTATTTTCCCCCTTTTCACAGAGAAATAAAGGTCTAGAAGTAGTTGGTCCTCTG
GCCTTAGTCATCAGCTTGGAGGAGGGGGCACCACCCCAGAGCCACAACATCTGCGCTTTTCTCTGGAGAAGATCTTGTTACAGGACCCAT
TATACCCCTATGTCCCGAAAGAATACTCTGGGGATCCCCCCAGGAGTGCTGCTGGCCTTTGGGGTAGAGGGTCCATGAGGTGCTCTGGGT
GGTGTCCTGTAGTGCAGTTCAGATTCATAGATGTCGGCCGAGTATTTGGGGGGTTAAGAGCAGGTGCCTTGGAACCAGACTGCCTGGGTC
CAAATTGTGGCTCCTTCAGTTAATAGACGTGTGACTAGGAGTAGCTTGTTAAGTCTTTATGAGCTCAGTTTTGTATTGTGTAAAATGAGA
GTTACAGTAATACCTAGATTGCAGGGTGGGTGGCGAGGACCAAGTGAATTAGTACCTGGAAAGTGTGTAACAGTTTCAACATGAGAAGTA
CACAACATGAGAAGCAGAGTTAGCTGTACATTGCCAGAGAACCCCCTGTGGGCCATTTCCTGTGTTCTTGAAGAAGACTTGGGCTTGGAC
CCTGTCCCCAGGAGGTCTCAGAGTAATCAGGACGGTACTAGGGAGAGAACTGTGGCAAGATAGATCAGTTATCTCGGTATCTATTCTCCC
CTTCCTAATGTAGAAGCTCTGATTTTTAACTGGGCAGATGACTACATGGATTCAAGGTATTTTCCTAGTGTCTCTTGAAATTAGGTGTGG
TATTGTGACCAAATTCTAGCCAAAAAGATGTTGAACAGAAGTGGTATATGCAGCTTCTAGGAAGTGTTCTTAAGGGGGAAGGCGTCATCC
CCCACCTTTCCTCCTTCCTGCACTCTGGAATGTGGACCAGATGGCTGGAGTAGGAGCTGCCACCTGGGGCCAGAAAATGATCTTAGGCGT
GAAGGTCAAGTAAGGCAGGACAAGAGAGAAGGAGCCTGCCTCCCCGAGGCTGTGAAGAGCCATGCCAGTACTGTCACCTGGGAGAATTAA

>102900_102900_2_ZNF773-PPP2R1A_ZNF773_chr19_58011481_ENST00000593916_PPP2R1A_chr19_52705197_ENST00000322088_length(amino acids)=574AA_BP=11
MAAATLRDPAQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVR
DKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKV
LELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVP
AFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKD
ECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSN
LKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNST

--------------------------------------------------------------
>102900_102900_3_ZNF773-PPP2R1A_ZNF773_chr19_58011481_ENST00000598770_PPP2R1A_chr19_52705197_ENST00000322088_length(transcript)=3324nt_BP=179nt
GTTGTTCGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCGGGTCTGAGGCTCGGTGGCGG
CGCCCAGGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCACGCTGAGGGACCCCGCTCAGC
TTCGCCTCAACAGCATCAAGAAGCTGTCCACCATCGCCTTGGCCCTTGGGGTTGAAAGGACCCGAAGTGAGCTTCTGCCTTTCCTTACAG
ATACCATCTATGATGAAGATGAGGTCCTCCTGGCCCTGGCAGAACAGCTGGGAACCTTCACTACCCTGGTGGGAGGCCCAGAGTACGTGC
ACTGCCTGCTGCCACCGCTGGAGTCGCTGGCCACAGTGGAGGAGACAGTGGTGCGGGACAAGGCAGTGGAGTCCTTACGGGCCATCTCAC
ACGAGCACTCGCCCTCTGACCTGGAGGCGCACTTTGTGCCGCTAGTGAAGCGGCTGGCGGGCGGCGACTGGTTCACCTCCCGCACCTCGG
CCTGCGGCCTCTTCTCCGTCTGCTACCCCCGAGTGTCCAGTGCTGTGAAGGCGGAACTTCGACAGTACTTCCGGAACCTGTGCTCAGATG
ACACCCCCATGGTGCGGCGGGCCGCAGCCTCCAAGCTGGGGGAGTTTGCCAAGGTGCTGGAGCTGGACAACGTCAAGAGTGAGATCATCC
CCATGTTCTCCAACCTGGCCTCTGACGAGCAGGACTCGGTGCGGCTGCTGGCGGTGGAGGCGTGCGTGAACATCGCCCAGCTTCTGCCCC
AGGAGGATCTGGAGGCCCTGGTGATGCCCACTCTGCGCCAGGCCGCTGAAGACAAGTCCTGGCGCGTCCGCTACATGGTGGCTGACAAGT
TCACAGAGCTCCAGAAAGCAGTGGGGCCTGAGATCACCAAGACAGACCTGGTCCCTGCCTTCCAGAACCTGATGAAAGACTGTGAGGCCG
AGGTGAGGGCCGCAGCCTCCCACAAGGTCAAAGAGTTCTGTGAAAACCTCTCAGCTGACTGTCGGGAGAATGTGATCATGTCCCAGATCT
TGCCCTGCATCAAGGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCTGCCCTGGCCTCAGTCATCATGGGTCTCTCTCCCATCTTGG
GCAAAGACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTGAAGGATGAGTGCCCTGAGGTACGGCTGAACATCATCTCTA
ACCTGGACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCCCTGCTCCCTGCCATTGTGGAGCTGGCTGAGGACGCCAAGT
GGCGGGTGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAGCTGGGAGTGGAGTTCTTTGATGAGAAACTTAACTCCTTGT
GCATGGCCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACCAGCAACCTGAAGAAGCTAGTGGAAAAGTTTGGGAAGGAGT
GGGCCCATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCCAACTACCTGCACCGCATGACTACGCTCTTCTGCATCAATG
TGCTGTCTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCCACGGTTCTGCGCATGGCTGGGGACCCGGTTGCCAATGTCC
GCTTCAATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAACAGCACCTTGCAGAGTGAAGTCAAGCCCATCCTAGAGAAGC
TGACCCAGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTGACTGTTCTGTCTCTCGCCTGATGCTGGAAGAGGAGCAAAC
ACTGGCCTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGAGACACTGGGGGGCCTTTGGCTGTCACTCCCTGTGCATGGT
CTGACCCCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGGGAAGATGTCTCACTGTCCACCTCCCAACGGGCTAGGGGAG
CACGGGGTTGGACAGGACAGTGACCTTGGGAGGAAGGGGCTACTCCGCCCACGTCAGGGAGAGATGTGAGCATCCCGGGTCACTGGATCC
TGCTGCTGTAATGGGAACCCCTCCCCCATTTACTTCTCCACCTCCCGTCCTCCCCATCATTGGTTTTTTTTTGTGTGTCAACTGTGCCGT
TTTTATTTTATTCCTTTTATTTTCCCCCTTTTCACAGAGAAATAAAGGTCTAGAAGTAGTTGGTCCTCTGGCCTTAGTCATCAGCTTGGA
GGAGGGGGCACCACCCCAGAGCCACAACATCTGCGCTTTTCTCTGGAGAAGATCTTGTTACAGGACCCATTATACCCCTATGTCCCGAAA
GAATACTCTGGGGATCCCCCCAGGAGTGCTGCTGGCCTTTGGGGTAGAGGGTCCATGAGGTGCTCTGGGTGGTGTCCTGTAGTGCAGTTC
AGATTCATAGATGTCGGCCGAGTATTTGGGGGGTTAAGAGCAGGTGCCTTGGAACCAGACTGCCTGGGTCCAAATTGTGGCTCCTTCAGT
TAATAGACGTGTGACTAGGAGTAGCTTGTTAAGTCTTTATGAGCTCAGTTTTGTATTGTGTAAAATGAGAGTTACAGTAATACCTAGATT
GCAGGGTGGGTGGCGAGGACCAAGTGAATTAGTACCTGGAAAGTGTGTAACAGTTTCAACATGAGAAGTACACAACATGAGAAGCAGAGT
TAGCTGTACATTGCCAGAGAACCCCCTGTGGGCCATTTCCTGTGTTCTTGAAGAAGACTTGGGCTTGGACCCTGTCCCCAGGAGGTCTCA
GAGTAATCAGGACGGTACTAGGGAGAGAACTGTGGCAAGATAGATCAGTTATCTCGGTATCTATTCTCCCCTTCCTAATGTAGAAGCTCT
GATTTTTAACTGGGCAGATGACTACATGGATTCAAGGTATTTTCCTAGTGTCTCTTGAAATTAGGTGTGGTATTGTGACCAAATTCTAGC
CAAAAAGATGTTGAACAGAAGTGGTATATGCAGCTTCTAGGAAGTGTTCTTAAGGGGGAAGGCGTCATCCCCCACCTTTCCTCCTTCCTG
CACTCTGGAATGTGGACCAGATGGCTGGAGTAGGAGCTGCCACCTGGGGCCAGAAAATGATCTTAGGCGTGAAGGTCAAGTAAGGCAGGA

>102900_102900_3_ZNF773-PPP2R1A_ZNF773_chr19_58011481_ENST00000598770_PPP2R1A_chr19_52705197_ENST00000322088_length(amino acids)=574AA_BP=11
MAAATLRDPAQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVR
DKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKV
LELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVP
AFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKD
ECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSN
LKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNST

--------------------------------------------------------------
>102900_102900_4_ZNF773-PPP2R1A_ZNF773_chr19_58011481_ENST00000599847_PPP2R1A_chr19_52705197_ENST00000322088_length(transcript)=3320nt_BP=175nt
TTCGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCGGGTCTGAGGCTCGGTGGCGGCGCC
CAGGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCACGCTGAGGGACCCCGCTCAGCTTCG
CCTCAACAGCATCAAGAAGCTGTCCACCATCGCCTTGGCCCTTGGGGTTGAAAGGACCCGAAGTGAGCTTCTGCCTTTCCTTACAGATAC
CATCTATGATGAAGATGAGGTCCTCCTGGCCCTGGCAGAACAGCTGGGAACCTTCACTACCCTGGTGGGAGGCCCAGAGTACGTGCACTG
CCTGCTGCCACCGCTGGAGTCGCTGGCCACAGTGGAGGAGACAGTGGTGCGGGACAAGGCAGTGGAGTCCTTACGGGCCATCTCACACGA
GCACTCGCCCTCTGACCTGGAGGCGCACTTTGTGCCGCTAGTGAAGCGGCTGGCGGGCGGCGACTGGTTCACCTCCCGCACCTCGGCCTG
CGGCCTCTTCTCCGTCTGCTACCCCCGAGTGTCCAGTGCTGTGAAGGCGGAACTTCGACAGTACTTCCGGAACCTGTGCTCAGATGACAC
CCCCATGGTGCGGCGGGCCGCAGCCTCCAAGCTGGGGGAGTTTGCCAAGGTGCTGGAGCTGGACAACGTCAAGAGTGAGATCATCCCCAT
GTTCTCCAACCTGGCCTCTGACGAGCAGGACTCGGTGCGGCTGCTGGCGGTGGAGGCGTGCGTGAACATCGCCCAGCTTCTGCCCCAGGA
GGATCTGGAGGCCCTGGTGATGCCCACTCTGCGCCAGGCCGCTGAAGACAAGTCCTGGCGCGTCCGCTACATGGTGGCTGACAAGTTCAC
AGAGCTCCAGAAAGCAGTGGGGCCTGAGATCACCAAGACAGACCTGGTCCCTGCCTTCCAGAACCTGATGAAAGACTGTGAGGCCGAGGT
GAGGGCCGCAGCCTCCCACAAGGTCAAAGAGTTCTGTGAAAACCTCTCAGCTGACTGTCGGGAGAATGTGATCATGTCCCAGATCTTGCC
CTGCATCAAGGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCTGCCCTGGCCTCAGTCATCATGGGTCTCTCTCCCATCTTGGGCAA
AGACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTGAAGGATGAGTGCCCTGAGGTACGGCTGAACATCATCTCTAACCT
GGACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCCCTGCTCCCTGCCATTGTGGAGCTGGCTGAGGACGCCAAGTGGCG
GGTGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAGCTGGGAGTGGAGTTCTTTGATGAGAAACTTAACTCCTTGTGCAT
GGCCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACCAGCAACCTGAAGAAGCTAGTGGAAAAGTTTGGGAAGGAGTGGGC
CCATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCCAACTACCTGCACCGCATGACTACGCTCTTCTGCATCAATGTGCT
GTCTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCCACGGTTCTGCGCATGGCTGGGGACCCGGTTGCCAATGTCCGCTT
CAATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAACAGCACCTTGCAGAGTGAAGTCAAGCCCATCCTAGAGAAGCTGAC
CCAGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTGACTGTTCTGTCTCTCGCCTGATGCTGGAAGAGGAGCAAACACTG
GCCTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGAGACACTGGGGGGCCTTTGGCTGTCACTCCCTGTGCATGGTCTGA
CCCCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGGGAAGATGTCTCACTGTCCACCTCCCAACGGGCTAGGGGAGCACG
GGGTTGGACAGGACAGTGACCTTGGGAGGAAGGGGCTACTCCGCCCACGTCAGGGAGAGATGTGAGCATCCCGGGTCACTGGATCCTGCT
GCTGTAATGGGAACCCCTCCCCCATTTACTTCTCCACCTCCCGTCCTCCCCATCATTGGTTTTTTTTTGTGTGTCAACTGTGCCGTTTTT
ATTTTATTCCTTTTATTTTCCCCCTTTTCACAGAGAAATAAAGGTCTAGAAGTAGTTGGTCCTCTGGCCTTAGTCATCAGCTTGGAGGAG
GGGGCACCACCCCAGAGCCACAACATCTGCGCTTTTCTCTGGAGAAGATCTTGTTACAGGACCCATTATACCCCTATGTCCCGAAAGAAT
ACTCTGGGGATCCCCCCAGGAGTGCTGCTGGCCTTTGGGGTAGAGGGTCCATGAGGTGCTCTGGGTGGTGTCCTGTAGTGCAGTTCAGAT
TCATAGATGTCGGCCGAGTATTTGGGGGGTTAAGAGCAGGTGCCTTGGAACCAGACTGCCTGGGTCCAAATTGTGGCTCCTTCAGTTAAT
AGACGTGTGACTAGGAGTAGCTTGTTAAGTCTTTATGAGCTCAGTTTTGTATTGTGTAAAATGAGAGTTACAGTAATACCTAGATTGCAG
GGTGGGTGGCGAGGACCAAGTGAATTAGTACCTGGAAAGTGTGTAACAGTTTCAACATGAGAAGTACACAACATGAGAAGCAGAGTTAGC
TGTACATTGCCAGAGAACCCCCTGTGGGCCATTTCCTGTGTTCTTGAAGAAGACTTGGGCTTGGACCCTGTCCCCAGGAGGTCTCAGAGT
AATCAGGACGGTACTAGGGAGAGAACTGTGGCAAGATAGATCAGTTATCTCGGTATCTATTCTCCCCTTCCTAATGTAGAAGCTCTGATT
TTTAACTGGGCAGATGACTACATGGATTCAAGGTATTTTCCTAGTGTCTCTTGAAATTAGGTGTGGTATTGTGACCAAATTCTAGCCAAA
AAGATGTTGAACAGAAGTGGTATATGCAGCTTCTAGGAAGTGTTCTTAAGGGGGAAGGCGTCATCCCCCACCTTTCCTCCTTCCTGCACT
CTGGAATGTGGACCAGATGGCTGGAGTAGGAGCTGCCACCTGGGGCCAGAAAATGATCTTAGGCGTGAAGGTCAAGTAAGGCAGGACAAG

>102900_102900_4_ZNF773-PPP2R1A_ZNF773_chr19_58011481_ENST00000599847_PPP2R1A_chr19_52705197_ENST00000322088_length(amino acids)=574AA_BP=11
MAAATLRDPAQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVR
DKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKV
LELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVP
AFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKD
ECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSN
LKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNST

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNF773-PPP2R1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF773-PPP2R1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF773-PPP2R1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource